YAMAMOTO Masatatsu 山本雅達

… Alternative Names

山本雅逹ヤマモトマサタツ

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Researcher Number	40404537
External Links
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help	2015 – 2025: 鹿児島大学, 医歯学域医学系, 助教 2017: 鹿児島大学, 医学部, 助教 2011 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 助教 2007 – 2009: 鹿児島大学, 大学院・医歯学総合研究科, 助教 2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology / Carcinogenesis Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 50010:Tumor biology-related / Basic Section 38020:Applied microbiology-related / Risk sciences of radiation and chemicals / Tumor biology / Biological Sciences
Keywords	Principal Investigator ABCB10 / 腫瘍学発ガン / 好中球 / RNAseq / 浸潤性小葉癌 / TGFシグナリング / がん微小環境 / ANKRD35 / 代謝 / 鉄 … More / tumor-initiating cells / 活性酸素 / TIC / Ros / ROS / 腫瘍学発癌 / PPIX / Abcb10 … More Except Principal Investigator DDS / ビフィズス菌 / オートファジー / 肺がん / BHLHE41 / 前臨床試験 / cytosine deaminase / 5FC（フルシトシン） / バイオDDS / がん / 糖鎖 / 微生物学 / サイトカイン / 免疫学的安全性 / 固形腫瘍 / 腫瘍発生 / アポトーシス / MYC / オートファジ― / BAX / 細胞死 / 非小細胞肺癌 / エイコサペンタエン酸 / 機能性乳酸菌 / 遺伝子改変 / ゲノム組込型ベクター / in vivo excision システム / ゲノム組み込み型宿主―ベクター / 乳酸菌の遺伝子改変技術 / ゲノム組み込み型ベクター / EPA / ゲノム改変 / 乳酸菌 / 水銀蓄積 / 水銀代謝 / HiCEP解析 / 肝臓 / 水銀 / フイリマングース / エピゲノム制御 / ゲノム不安定性 / 遺伝子修復 / 抗がん剤耐性 / 遺伝子コピー数変化 / がん抑制遺伝子 / 薬剤耐性 / ゲノムj / コピー数 / コピー数変化 / コピー数変異 / RRM1 / 遺伝子増幅 / survivin / Arsenite / p38 / Apoptosis / Akt / PI3K / 2-deoxy-L-ribose / MMP-9 / Thymidine phosphorylase / fibroblast / c-myc / EGR1 / TSP1 / 5FU / apoptosis / drug resistance / thymdine phosphorylase / 線維芽細胞 / マイクロDNA / 5-Fu / BNIP3 / HIF-1 / IkB / β / IKKα / NF-κB / TP / 血管新生阻害効果 / GBL / NADPHオキシダーゼTegafur / Thymidine phosphorylase (TP) / 5-FU / TSP-1 / NFκB / ROS / IL-8 / 2-deoxy-D-ribose / thymidine phosphorylase Less

ビフィズス菌による腫瘍局所5FU産生と選択圧を生じるプラスミド安定保持株の作製Principal Investigator
- Principal Investigator
  
  山本雅達
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Selective antitumor molecule production system in solid tumors by Bifidobacteria-the Immunological advantages and safety
- Principal Investigator
  
  谷口俊一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
β-グルクロニダーゼ発現・分泌ビフィズス菌株樹立と固形がん治療への応用
- Principal Investigator
  
  下川倫子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Challenge to refractory cervical cancer using a foci-specific anticancer drug production biosystem
- Principal Investigator
  
  小林裕明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kagoshima University
がん微小環境のANKRD35-TGFβ1作用性のN1/N2好中球リモデリングPrincipal Investigator
- Principal Investigator
  
  山本雅達
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagoshima University
Mechanisms analysis of lung cancer suppression and cell death by an autophagy inducible gene BHLHE41.
- Principal Investigator
  
  Tatsuhiko Furukawa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagoshima University
Establishment of a novel genome modification technology to produce functional lactic acid bacteria
- Principal Investigator
  
  Kashige Nobuhiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Fukuoka University
Construction of tumor-development mice model using Abcb10 knock out mice exhibiting PPIX accumulationPrincipal Investigator
- Principal Investigator
  
  Yamamoto Masatatsu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagoshima University
Evaluation of moleclar bases for suppression of gene amplification
- Principal Investigator
  
  Furukawa Tatsuhiko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kagoshima University
Identify and database creation of gene expression related mercury in liver of the small Indian mongoose using HiCEP analysis
- Principal Investigator
  
  Horai Sawako
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tottori University
Construction of tumor-development mice model using Abcb10 knock out mice exhibiting PPIX accumulationPrincipal Investigator
- Principal Investigator
  
  Yamamoto Masatatsu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kagoshima University
Generation of malignant tumor model by heme synthesis failure using mice with Abcb10 deficientPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Masatatsu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Kagoshima University
Molecular targeting agents that suppress invasion and metastasis of cancer cells
- Principal Investigator
  
  AKIYAMA Shinichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University

[Journal Article] Approach to Functions of BHLHE41/DEC2 in Non-Small Lung Cancer Development2023
- Author(s)
  Furukawa Tatsuhiko、Mimami Kentaro、Nagata Toshiyuki、Yamamoto Masatasu、Sato Masami、Tanimoto Akihide
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 14 Pages: 11731-11731
- DOI
  10.3390/ijms241411731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08324, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-21K07129
[Journal Article] Nucleolar Stress Response via Ribosomal Protein L11　Regulates Topoisomerase Inhibitor Sensitivity of p53-Intact Cancers2022
- Author(s)
  Ishihara Y, Nakamura K, Nakagawa S, Okamoto Y, Yamamoto M, Furukawa T, Kawahara　K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 24 Pages: 15986-15986
- DOI
  10.3390/ijms232415986
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K07103, KAKENHI-PROJECT-21K07129, KAKENHI-PROJECT-22K15900, KAKENHI-PROJECT-22H04922
[Journal Article] Metabolic reprograming of cancer as a therapeutic target.2022
- Author(s)
  Furukawa T, Tabata S, Minami K, Yamamoto M, Kawahara K, Tanimoto A
- Journal Title
  
  Biochim Biophys Acta Gen Subj
  
  Volume: 1867 Issue: 3 Pages: 130301-130301
- DOI
  10.1016/j.bbagen.2022.130301
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K07103, KAKENHI-PROJECT-21K07129, KAKENHI-PROJECT-22K07150, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-17KK0199
[Journal Article] Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS2021
- Author(s)
  Kogaki T, Ohshio I, Ura H, Iyama S, Kitae K, Morie T, Fujii S, Sato S, Nagata T, Takeda AH, Aoki M, Ueda K, Minami K, Yamamoto M, Kawahara K, Furukawa T, Sato M, Ueda Y, Jingushi K, Tozuka Z, Saigusa D, Hase H, Tsujikawa K.
- Journal Title
  
  J Pharm Biomed Anal.
  
  Volume: 197 Pages: 113943-113954
- DOI
  10.1016/j.jpba.2021.113943
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K07129
[Journal Article] ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer.2021
- Author(s)
  Kentaro Jingushi,Masaya Aoki,Kazuhiro Ueda,Takahiro Kogaki,Masaya Tanimoto,Yuya Monoe,Masayuki Ando,Takuya Matsumoto,Kentaro Minami,Yuko Ueda,Kaori Kitae,Hiroaki Hase,Toshiyuki Nagata,Aya Harada-Takeda,Masatatsu Yamamoto,Kohichi Kawahara,Kazuhiro Tabata,Tatsuhiko Furukawa,Masami Sato,Kazutake Tsujikawa
- Journal Title
  
  Scientific reports
  
  Volume: 11 Issue: 1 Pages: 8677-8677
- DOI
  10.1038/s41598-021-87763-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K07129, KAKENHI-PROJECT-19K22566
[Journal Article] BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma.2021
- Author(s)
  Toshiyuki Nagata, Kentaro Minami, Masatatsu Yamamoto, Tsubasa Hiraki, Masashi Idogawa, Katsumi Fujimoto, Shun Kageyama, Kazuhiro Tabata, Kohichi Kawahara, Kazuhiro Ueda, Ryuji Ikeda, Yukio Kato, Masaaki Komatsu, Akihide Tanimoto, Tatsuhiko Furukawa, Masami Sato
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 22 Issue: 21 Pages: 11509-11509
- DOI
  10.3390/ijms222111509
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-18K09638, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-20K09181, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K07129, KAKENHI-PROJECT-19K22566
[Journal Article] FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer2020
- Author(s)
  Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Yamamoto M, Minami K, Shimokawa M, Arigami T, Yanagita S, Matushita D, Uenosono Y, Ishigami S, Kijima Y, Maemura K, Kitazono I, Tanimoto A, Furukawa T, Natsugoe S
- Journal Title
  
  Oncogenesis
  
  Volume: 9 Issue: 2 Pages: 13-13
- DOI
  10.1038/s41389-020-0190-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] Combination of hydroxyurea and tranilast suppresses gemcitabine resistance induced by ribonucleotide reductase M1 in gemcitabine-resistant cells2020
- Author(s)
  Shinagawa N, Minami K, Ishida T, Hijioka H, Yamamoto M, Kawahara K, Furukawa T, Nakamura N
- Journal Title
  
  Oral Sci Int
  
  Volume: - Issue: 3 Pages: 1-9
- DOI
  10.1002/osi2.1096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K07129
[Journal Article] Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5?FU2020
- Author(s)
  Kawahata T, Kawahara K, Shimokawa M, Sakiyama A, Shiraishi T, Minami K, Yamamoto M, Shinsato Y, Arima K, Hamada T, Furukawa T.
- Journal Title
  
  Oncology Letters
  
  Volume: 19 Pages: 2258-2264
- DOI
  10.3892/ol.2020.11352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K06732, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-17J05291, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis2019
- Author(s)
  Higa N, Shinsato Y, Kamil M, Hirano T, Takajo T, Shimokawa M, Minami K, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 24 Pages: 6355-6355
- DOI
  10.3390/ijms20246355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-18K16590, KAKENHI-PROJECT-16H06276
[Journal Article] MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-22019
- Author(s)
  Hirono T, Jingushi K, Nagata T, Sato M, Minami K, Aoki M, Takeda AH, Umehara T, Egawa H, Nakatsuji Y, Kitae K, Ueda Y, Hase H, Yamamoto M, Shinsato Y, Kawahara K, Furukawa T, Tsujikawa K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 6956-6956
- DOI
  10.1038/s41598-019-43355-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-17H04125, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-17K10796
[Journal Article] High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme2019
- Author(s)
  Kamil M, Shinsato Y, Higa N, Hirano T, Idogawa M, Takajo T, Minami K, Shimokawa M, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K.
- Journal Title
  
  Br J Cancer
  
  Volume: 120 Issue: 8 Pages: 819-826
- DOI
  10.1038/s41416-019-0413-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10871, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16K09285
[Journal Article] 5-Aza-2-deoxycytidine Enhances the Sensitivity of 5-Fluorouracil by Demethylation of the Thymidine Phosphorylase Promoter2019
- Author(s)
  Nishizawa Y, Ikeda R, Yamamoto M, Kawahara K, Shinsato Y, Minami K, Nitta M, Terazono H, Akiyama SI, Furukawa T, Takeda Y
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 8 Pages: 4129-4136
- DOI
  10.21873/anticanres.13571
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K06788, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] Thymidine phosphorylase in cancer aggressiveness and　chemoresistance2018
- Author(s)
  Furukawa T, Tabata S, Yamamoto M, Kawahara K, Shinsato Y, Minami K, Shimokawa M, Akiyama SI.
- Journal Title
  
  Pharmacological Research
  
  Volume: 28 Pages: 15-20
- DOI
  10.1016/j.phrs.2018.03.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-18K15248
[Journal Article] Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells2018
- Author(s)
  Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Toyoda Y, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama S
- Journal Title
  
  Scientific Reports
  
  Volume: 印刷中
- NAID
  120006875668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] Thymidine Catabolism as a Metabolic Strategy for Cancer Survival2017
- Author(s)
  Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama SI
- Journal Title
  
  Cell Rep
  
  Volume: 19 Issue: 7 Pages: 1313-1321
- DOI
  10.1016/j.celrep.2017.04.061
- NAID
  120007001420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460201, KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-16H05309, KAKENHI-PROJECT-16K14619, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-15K21364, KAKENHI-PROJECT-16K07121
[Journal Article] Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.2017
- Author(s)
  Tanabe K, Shinsato Y, Furukawa T, Kita Y, Hatanaka K, Minami K, Kawahara K, Yamamoto M, Baba K, Mori S, Uchikado Y, Maemura K, Tanimoto A, Natsugoe S.
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 4 Pages: 6353-6363
- DOI
  10.18632/oncotarget.14087
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293306, KAKENHI-PROJECT-26670160, KAKENHI-PROJECT-15K10108, KAKENHI-PROJECT-16K10510, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-16K07121
[Journal Article] Oral aversion to dietary sugar, ethanol and glycerol correlates with alterations in specific hepatic metabolites in a mouse model of human citrin deficiency.2017
- Author(s)
  Saheki T, Inoue K, Ono H, Fujimoto Y, Furuie S, Yamamura KI, Kuroda E, Ushikai M, Asakawa A, Inui A, Eto K, Kadowaki T, Moriyama M, Sinasac DS, Yamamoto T, Furukawa T, Kobayashi K.
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 120 Issue: 4 Pages: 306-316
- DOI
  10.1016/j.ymgme.2017.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-15K01623, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-19K22566
[Journal Article] ATP7B expression confers multidrug resistance through drug sequestration2016
- Author(s)
  Moinuddin FM, Shinsato Y, Komatsu M, Mitsuo R, Minami K, Yamamoto M, Kawahara K, Hirano H, Arita K, Furukawa T.
- Journal Title
  
  Oncotarget.
  
  Volume: 7 Pages: 22779-90
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors2015
- Author(s)
  Minami K, Shinsato Y, Yamamoto M, Takahashi H, Zhang S, Nishizawa Y, Tabata S, Ikeda R, Kawahara K, Tsujikawa K, Chijiiwa K, Yamada K, Akiyama S, Torras S, Pastor-Anglada M, Furukawa T, Yasuo T.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 127 Issue: 3 Pages: 319-325
- DOI
  10.1016/j.jphs.2015.01.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430114, KAKENHI-PROJECT-25461703, KAKENHI-PROJECT-26870576, KAKENHI-PROJECT-26890020, KAKENHI-PROJECT-26670160
[Journal Article] ATP7B expression confers multidrug resistance through drug sequestration2015
- Author(s)
  Moinuddin FM, Shinsato Y, Komatsu M, Mitsuo R, Minami K, Yamamoto M, Kawahara K, Hirano H, Arita K, Furukawa T
- Journal Title
  
  Oncotarget
  
  Volume: NA Issue: 16 Pages: 22779-22790
- DOI
  10.18632/oncotarget.8059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670160, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-25430114, KAKENHI-PROJECT-16K07875
[Journal Article] Expression of ABCB6 Is Related to Resistance to 5-FU, SN-38 and Vincristine., Anticancer Res2014
- Author(s)
  Minami K, Kamijo Y, Nishizawa Y, Tabata S, Horikuchi F, Yamamoto M, Kawahara K, Shinsato Y, Tachiwada T, Chen ZS, Tsujikawa K, Nakagawa M, Seki N, Akiyama S, Arima K, Takeda Y, Furukawa T
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Pages: 4767-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose.2014
- Author(s)
  Ikeda R, Tabata S, Tajitsu Y, Nishizawa Y, Minami K, Furukawa T, Yamamoto M, Shinsato Y, Akiyama S, Yamada K, Takeda Y
- Journal Title
  
  Oncol Rep
  
  Volume: 3 Issue: 3 Pages: 1444-8
- DOI
  10.3892/or.2013.2572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037, KAKENHI-PROJECT-25430114
[Journal Article] Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs2014
- Author(s)
  Nakao S, Mabuchi M, Shimizu T, Itoh Y, Takeuchi Y, Ueda M, Mizuno H, Shigi N, Ohshio I, Jinguji K, Ueda Y, Yamamoto M, Furukawa T, Aoki S, Tsujikawa K, Tanaka A.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: Vol.24,No.3 Pages: 1071-1074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Recombinant fusion protein of cholera toxin B subunit with YVAD secreted by Lactobacillus casei inhibits lipopolysaccharide-induced caspase-1 activation and subsequent IL-1 beta secretion in Caco-2 cells2014
- Author(s)
  Yukihiro Hiramatsu, Masatatsu Yamamoto, Tomomitsu Satho, Keiichi Irie, Akiko Kai, Saori Uyeda, Yuki Fukumitsu, Akihisa Toda, Takeshi Miyata, Fumio Miake, Takeshi Arakawa and Nobuhiro Kashige
- Journal Title
  
  BMC Biotechnology
  
  Volume: 14 Issue: 1 Pages: 1-9
- DOI
  10.1186/1472-6750-14-38
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Abcb10 role in heme biosynthesis in vivo : Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation2014
- Author(s)
  Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, Kanekura T, Nakagawa M, Akiyama S, Furukawa T
- Journal Title
  
  Mol Cell Biol.
  
  Volume: Vol.34,No.6 Pages: 1077-1084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.2014
- Author(s)
  Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, Kanekura T, Nakagawa M, Akiyama S, Furukawa T
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 6 Issue: 6 Pages: 1077-84
- DOI
  10.1128/mcb.00865-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037, KAKENHI-PROJECT-25430114, KAKENHI-PROJECT-25461702
[Journal Article] Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma.2014
- Author(s)
  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Kawahara K, Yamamoto M, Hirano H, Tokimura H, Arita K
- Journal Title
  
  Oncotarget.
  
  Volume: 12 Pages: 2261-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Establishment of a primary hepatocyte culture from the small Indian mongoose (Herpestes auropunctatus) and distribution of mercury in liver tissue2014
- Author(s)
  Horai S, Yanagi K, Kaname T, Yamamoto M, Watanabe I, Ogura G, Abe S, Tanabe S, Furukawa T
- Journal Title
  
  Ecotoxicology
  
  Volume: 23 Issue: 9 Pages: 1681-9
- DOI
  10.1007/s10646-014-1307-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430114, KAKENHI-PROJECT-26430194
[Journal Article] Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells.2014
- Author(s)
  Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che XF, Sumizawa T, Nitta M, Yamaguchi T, Yamamoto M, Tabata S, Akiyama S, Yamada K, Furukawa T, Takeda Y
- Journal Title
  
  Int J Mol Med
  
  Volume: 3 Issue: 3 Pages: 703-8
- DOI
  10.3892/ijmm.2013.1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037, KAKENHI-PROJECT-25430114
[Journal Article] Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells2014
- Author(s)
  Tabata S, Ikeda R, Yamamoto M, Shimaoka S, Mukaida N, Takeda Y, Yamada K, Soga T, Furukawa T, Akiyama S
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 10473-10485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs.2014
- Author(s)
  S. Nakao, M. Mabuchi, T.Shimizu, Y. Itoh, Y. Takeuchi, M. Ueda, H. Mizuno, N. Shigi, I. Ohshio, K. Jinguji, Y. Ueda, M. Yamamoto, T. Furukawa, S. Aoki, K. Tsujikawa, A. Tanaka
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 24 Issue: 4 Pages: 1071-1074
- DOI
  10.1016/j.bmcl.2014.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510284, KAKENHI-PROJECT-23701037, KAKENHI-PROJECT-25430114
[Journal Article] VEGF expression is augmented by hypoxia-induced PGIS in human fibroblasts.2013
- Author(s)
  Wang J, Ikeda R, Che XF, Ooyama A, Yamamoto M, Furukawa T, Hasui K, Zheng CL, Tajitsu Y, Oka T, Tabata S, Nishizawa Y, Eizuru Y, Akiyama S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 3 Issue: 3 Pages: 746-54
- DOI
  10.3892/ijo.2013.1994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma.2013
- Author(s)
  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Kawahara K, Yamamoto M, Hirano H, Tokimura H, Arita K.
- Journal Title
  
  Oncotarget.
  
  Volume: １２ Pages: 2261-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Influence of gefitinib and erlotinib on apoptosis and c-MYC expression in H23 lung cancer cells.2013
- Author(s)
  Suenaga M, Yamamoto M, Tabata S, Itakura S, Miyata M, Hamasaki S, Furukawa T.
- Journal Title
  
  Anticancer Res.
  
  Volume: 4 Pages: 1547-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430114
[Journal Article] Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells2013
- Author(s)
  Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che XF, Sumizawa T, Nitta M, Yamaguchi T, Yamamoto M, Tabata S, Akiyama S, Yamada K, Furukawa T, Takeda Y
- Journal Title
  
  Int J Mol Med.
  
  Volume: Vol.32,No.3 Pages: 703-708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Influence of gefitinib and erlotinib on apoptosis and c-MYC expression in H23 lung cancer cells2013
- Author(s)
  Suenaga M, Yamamoto M, Tabata S, Itakura S, Miyata M, Hamasaki S, Furukawa T
- Journal Title
  
  Anticancer Res
  
  Volume: Vol.33,No.4 Pages: 1547-1554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] VEGF expression is augmented by hypoxia-induced PGIS in human fibroblasts2013
- Author(s)
  Wang J, Ikeda R, Che XF, Ooyama A, Yamamoto M, Furukawa T, Hasui K, Zheng CL, Tajitsu Y, Oka T, Tabata S, Nishizawa Y, Eizuru Y, Akiyama S
- Journal Title
  
  Int J Oncol.
  
  Volume: Vol.43,No.3 Pages: 746-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose2013
- Author(s)
  Ikeda R, Tabata S, Tajitsu Y, Nishizawa Y, Minami K, Furukawa T, Yamamoto M, Shinsato Y, Akiyama S, Yamada K, Takeda Y
- Journal Title
  
  Oncol Rep.
  
  Volume: Vol.30,No.3 Pages: 1444-1448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Influence of gefitinib and erlotinib on apoptosis and c-MYC expression in H23 lung cancer cells.2013
- Author(s)
  Suenaga M, Yamamoto M, Tabata S, Itakura S, Miyata M, Hamasaki S, Furukawa T
- Journal Title
  
  Anticancer Res
  
  Volume: 4 Pages: 1547-54
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma2013
- Author(s)
  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Kawahara K, Yamamoto M, Hirano H, Tokimura H, Arita K
- Journal Title
  
  Oncotarget.
  
  Volume: Vol.4,No.12 Pages: 2261-2270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells2012
- Author(s)
  Tabata S1, Ikeda R, Yamamoto M, Furukawa T, Kuramoto T, Takeda Y, Yamada K, Haraguchi M, Nishioka Y, Sone S, Akiyama S
- Journal Title
  
  Oncol Rep.
  
  Volume: Vol.3 Pages: 895-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701037
[Journal Article] Thymidine phosphorylase inhibits the expression of proapoptic protein BNIP3. Biochem.2008
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama, Katsushi Yamada, (他11名15番目)
- Journal Title
  
  Biophys. Res. Commun. 370
  
  Pages: 220-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Anti-angiogenic effect of 5-fluorouracil-based drugs against human colon cancer xenografts.2008
- Author(s)
  Akio Ooyama, Masatatsu Yamamoto, Shin-ichi Akiyama, Masakazu Fukushima, (他2名5番目)
- Journal Title
  
  Cancer Lett. 267
  
  Pages: 26-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in KM12C cells.2008
- Author(s)
  Hong-Ye Zhao, Masatatsu Yamamoto, Tatsuhiko Furukawa, Michihiko Kuwano, Shin-ichi Akiyama, (他10名15番目)
- Journal Title
  
  Cancer Lett. 270
  
  Pages: 156-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.2008
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Katsushi Yamada, Shin-ichi Akiyama., (他14名19番目)
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 3017-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU.2008
- Author(s)
  Hong-Ye Zhao, Masatatsu Yamamoto, Tatsuhiko Furukawa, Michihiko Kuwano, Shin-ichi Akiyama, (他10名15番目)
- Journal Title
  
  Cancer Res. 68
  
  Pages: 7035-7041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Copper-Transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer.2007
- Author(s)
  Saruski Owatari, Masatatsu Yamamoto, Shin-ichi Akiyama, Tatsuhiko Furukawa, (他11名14番目)
- Journal Title
  
  Cancer Res. 67
  
  Pages: 4860-4868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Isolation and characterization of arsenite-resistant human epidermoid carcinoma KB cells.2007
- Author(s)
  Tokushi Tachiwada, Tatsuhiko Furukawa, Masatatsu Yamamoto, Masayuki Nakagawa, Shin-ichi Akiyama:, (他8名13番目)
- Journal Title
  
  Oncol. Rep. 8
  
  Pages: 721-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] A functional role of intracellular loops of human multidrug resistance protein 1.2006
- Author(s)
  Xiao-Qin Ren, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama:, (他3名7番目)
- Journal Title
  
  J. Biochem (Tokyo) 140
  
  Pages: 313-318
- NAID
  10018841960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] 2-Deoxy-D-ribose inhibits hypoxiainduced apoptosis by suppressing the phosphorylation of p38 MAPK. Biochem.2006
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama:, (他10名14番目)
- Journal Title
  
  Biophys. Res. Commun. 342
  
  Pages: 280-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] 2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylaseoverexpressing tumors by suppressing matrix metalloprotease-9.2006
- Author(s)
  Yuichi Nakajima, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他3名7番目)
- Journal Title
  
  Int. J. Cacncer 119
  
  Pages: 1710-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Overexpression of survivin in primary ATL cells and sodium arsenite induces apoptosis by down-regulating survivin expression in ATL cell lines.2006
- Author(s)
  Xiao-Fang Che, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他8名12番目)
- Journal Title
  
  Blood 15
  
  Pages: 4880-4887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-flurouracil in human carcinoma cells.
- Author(s)
  Shigeto Matushita, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他13名17番目)
- Journal Title
  
  Int. J. Oncol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] オートファジ―誘導遺伝子BHLHE41の抗腫瘍活性2022
- Author(s)
  古川龍彦、南謙太朗、永田俊之、山本雅達、河原康一、蔭山　俊、小松勝明、佐藤雅美
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-21K07129
[Presentation] インテグリンβ５阻害剤はFARP1-CDC42経路を通じて胃がんの浸潤性を低下させる2022
- Author(s)
  古川龍彦、南　謙太朗、河原康一、山本雅達
- Organizer
  第95回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K07129
[Presentation] インテグリンβ5-FARP1-CDC42経路を通じた胃癌細胞の浸潤性の制御とその阻害2022
- Author(s)
  古川龍彦、山本雅達、河原康一、南謙太朗
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07129
[Presentation] FARP1はインテグリンαvβ5に結合し、その発現上昇は進行胃がんの予後に関わる2021
- Author(s)
  古川龍彦、南　謙太朗、山本雅達、河原康一
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07129
[Presentation] 遺伝子増幅を制御する分子による抗癌剤耐性の克服2019
- Author(s)
  南謙太朗、中岡博史、山本雅達、新里能成、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] BHLHE41/DEC2によって遺伝子増幅は減少する2019
- Author(s)
  南謙太朗、山本雅達、中岡博史、落合博、下川倫子、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] DEC2は肺腺癌においてオートファジー細胞死を誘導する2019
- Author(s)
  南謙太朗, 山本雅達, 新里能成, 河原康一, 佐藤雅美, 古川龍彦
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 腫瘍抑制因子BHLHE41のユビキチンプロテアゾーム経路による分解2018
- Author(s)
  南謙太郎、山本雅達、新里能成、河原康一、関原和正、佐藤雅美、古川龍彦,
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] Thymidine catabolism and cancer2018
- Author(s)
  古川龍彦, 田畑祥、山本雅達、南謙太郎、河原康一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] TP発現による解糖系を介した低栄養適応性の賦与2018
- Author(s)
  古川龍彦, 田畑祥、山本雅達、南謙太郎
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] ATP7B is involved in doxorubicine relocalization from nuclei to late endosome and anticancer agent resistance2017
- Author(s)
  古川龍彦、新里能成、小松正治、南謙太朗、永田俊行、山本雅達、河原康一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 細胞分裂の異常を監視する核小体の新たな役割2017
- Author(s)
  川畑拓斗、河原康一、下川倫子、上條陽平、白石岳大、朝日汰一、山本雅達、新里能成、南謙太朗、武井孝行、吉田昌弘、有馬一成、濱田季之、古川龍彦
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体の再編成により細胞分裂を制御する新たなストレス応答と癌治療薬の開発2016
- Author(s)
  下川倫子, 河原康一, 川畑拓斗, 上條陽平, 白石岳大, 山本雅達, 新里能成, 南謙太朗, 有馬一成, 濱田季之, 古川龍彦
- Organizer
  第８９回生化学会大会
- Place of Presentation
  仙台国際センター東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体ストレス応答による細胞分裂監視機構とこれを利用した抗がん剤の開発2016
- Author(s)
  河原康一、川畑拓斗、下川倫子、上條陽平、白石岳大、山本雅達、新里能成、南謙太朗、有馬一成、濱田季之、古川龍彦
- Organizer
  日本ケミカルバイオロジー学会　第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] エネルギー代謝を制御する核小体ストレス応答の分裂期チェックポイント機構としての新たな役割の解明2016
- Author(s)
  川畑　拓斗、河原　康一、下川　倫子、山本　雅達、新里　能成、南　謙太朗、有馬　一成、濱田　季之、古川　龍彦
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 『遺伝子組換え乳酸菌を用いた腸管内DDSの開発と腸管疾患への応用に向けて』2015
- Author(s)
  山本雅達
- Organizer
  霧島神経薬理フォーラム
- Place of Presentation
  鹿児島県霧島市霧島国際ホテル
- Year and Date
  2015-08-16
- Invited
- Data Source
  KAKENHI-PROJECT-25430114
[Presentation] KB3-1細胞における5-aza-2-deoxycytidine (5-AZ)による 5-fluorouracil (5-FU)の抗腫瘍効果増強作用2014
- Author(s)
  西澤由紀彦、池田龍二、田實裕介、河原康一、山本雅達、新里能成、南謙太郎、古川龍彦、武田泰生
- Organizer
  日本薬理学会本会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10 knockout mice causes anemia with protoporphyrin IX and iron accumulation : Abcb10 is essential for heme biosynthesisin vivo2014
- Author(s)
  山本雅達
- Organizer
  生体制御・創薬研究ワークショップ
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10 knockout mice causes anemia with protoporphyrin IX and iron accumulation: Abcb10 is essential for heme biosynthesis in vivo.2014
- Author(s)
  山本雅達
- Organizer
  生体制御・創薬研究ワークショップ
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25430114
[Presentation] Abcb10 knockout mice causes anemia with protoporphyrin IX and iron accumulation: Abcb10 is essential for heme biosynthesis in vivo.2014
- Author(s)
  山本雅達
- Organizer
  生体制御・創薬研究ワークショップ
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはProtoporphyrin IXと鉄の高蓄積と血球分化不全を示す2013
- Author(s)
  山本雅達
- Organizer
  第8回トランスポーター研究会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはProtoporphyrin IXと鉄の高蓄積と血球分化不全を示す2013
- Author(s)
  山本雅達、有村　博史、福重　智子、河原　康一、中川　昌之、金蔵　拓郎、古川龍彦
- Organizer
  第８回トランスポーター研究会年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Gemcitabine耐性膵癌細胞MGEM6で増加した RRM1のノックダウンはgemcitabineの細胞内蓄積量を増加させる2013
- Author(s)
  南謙太朗、山本雅達、新里能成、河原康一、小松政治、池田龍二、西澤由紀彦、田畑祥、秋山伸一、山田勝士、古川龍彦、武田泰生
- Organizer
  日本薬理学会西南部会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはProtoporphyrin IXと鉄の高蓄積と血球分化不全を示す2013
- Author(s)
  山本雅達、有村　博史、福重　智子、河原　康一、中川　昌之、金蔵　拓郎、古川龍彦
- Organizer
  第８回トランスポーター研究会年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-25430114
[Presentation] ヒト癌細胞の ROS産生および生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥,池田龍二,山本雅達,古川龍彦,倉本卓哉,後東久嗣,埴淵昌毅,西岡安彦,曽根三郎,秋山伸一
- Organizer
  第16回日本がん分子標的治療学会学術集会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはヒトErythropoietic protoporphyriaと類似の病態を示す2012
- Author(s)
  山本雅達
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] CNT1とRRM1の発現変化がGemcitabine耐性膵癌細の耐性に関与している2012
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、池田龍二、山本雅達、武田泰生
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10, the gene knockout mice exhibit similar to human Erythropoietic protoporphyria, is essential for Heme synthesis2012
- Author(s)
  山本雅達、有村博史、福重智子、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第7回トランスポーター研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] ヒト癌細胞の生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥,池田龍二,山本雅達,古川龍彦,倉本卓哉,後東久嗣,埴淵昌毅,西岡安彦,曽根三郎,秋山伸一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] シンポジウム2S13生体遷移金属のパラダイムシフト : 生体内シグナル分子としての機能『Abcb10はHeme合成に必須であって、その欠損マウスはヒトErythropoietic protoporphyriaと類似の病態を示す』2012
- Author(s)
  山本雅達
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはヒトErythropoietic protoporphyriaと類似の病態を示す2011
- Author(s)
  山本雅達、有村博史、福重智子、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] 癌細胞での 5-FU依存的 early growthresponse protein-1およびthrombospondin-1発現亢進におけるthymidinephosphorylaseの役割2011
- Author(s)
  西澤由紀彦、池田龍二、松下茂人、田畑祥、山本雅達、南謙太郎、山口辰哉、秋山伸一、古川龍彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Gemcitabine耐性膵臓癌細胞のCNT1とRRM1の耐性機構への関与2011
- Author(s)
  南謙太朗、古川龍彦、山本雅達、西澤由紀彦、田畑祥、池田龍二、小松正治、秋山伸一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23701037
[Presentation] Abcb10はHeme合成に必須であって、その欠損マウスはヒトErythropoietic protoporphyriaと類似の病態を示す。2011
- Author(s)
  山本雅達，有村博史，福重智3，中川昌之，金蔵拓郎，古川龍彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23701037

1. FURUKAWA Tatsuhiko (40219100)

# of Collaborated Projects: 4 results

# of Collaborated Products: 30 results
2. 谷口俊一郎 (60117166)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 小林裕明 (70260700)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 河原康一 (00400482)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
5. 下川倫子 (50843611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. AKIYAMA Shinichi (60117413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. Horai Sawako (60512689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Kashige Nobuhiro (80185751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 井ノ上逸朗 (00192500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 南謙太朗 (20735956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
11. 佐藤朝光 (90369025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 肥田重明 (10345762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 戸上真一 (20644769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 簗詰伸太郎 (40623343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 水野美香 (50588837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IKEDA Ryuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. UCHIKADO Yasuto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. NAGATA Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. OKAMOTO Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 夏越祥次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 盛真一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 森山光章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 辻川和丈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 青木俊二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAMOTO Masatatsu 山本 雅達

山本 雅逹 ヤマモト マサタツ

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ビフィズス菌による腫瘍局所5FU産生と選択圧を生じるプラスミド安定保持株の作製Principal Investigator

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がん微小環境のANKRD35-TGFβ1作用性のN1/N2好中球リモデリングPrincipal Investigator

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Construction of tumor-development mice model using Abcb10 knock out mice exhibiting PPIX accumulationPrincipal Investigator

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Construction of tumor-development mice model using Abcb10 knock out mice exhibiting PPIX accumulationPrincipal Investigator

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Generation of malignant tumor model by heme synthesis failure using mice with Abcb10 deficientPrincipal Investigator

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[Journal Article] Approach to Functions of BHLHE41/DEC2 in Non-Small Lung Cancer Development2023

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YAMAMOTO Masatatsu 山本雅達

山本雅逹ヤマモトマサタツ

[Journal Article] Nucleolar Stress Response via Ribosomal Protein L11　Regulates Topoisomerase Inhibitor Sensitivity of p53-Intact Cancers2022

[Journal Article] Thymidine phosphorylase in cancer aggressiveness and　chemoresistance2018