Ogi Kazuhiro 荻和弘

… Alternative Names

荻和弘オギカズヒロ

OGI Kazuhiro 荻和弘

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Researcher Number	40433114
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 札幌医科大学, 医学部, 講師 2019 – 2023: 札幌医科大学, 医学部, 講師 2014 – 2017: 札幌医科大学, 医学部, 講師 2013: 札幌医科大学, 医学部, 助教 2012: 札幌医科大学, 医学部, 訪問研究員 2007 – 2011: Sapporo Medical University, School of Medicine, Dept Oral Surgery, Instructor 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 口腔癌 / がん免疫環境 / 遺伝子変異 / 免疫チェックポイント阻害剤 / 再発口腔がん / がん微小環境 / NF-kB / 血管新生因子 / HIF-1 alpha / 遺伝子変異量 … More / 免疫チェックポイント阻害薬 / 再発口腔癌 / gene mutation / squamous cell carcinoma / Immunotherapy / 放射線治療 / 代謝調節 / DNA修復能 / 放射線耐性 / 糖代謝 / GLUT-1 / 糖代謝阻害剤 / グルコーストランスポーター / 糖代謝阻害薬 / CHFR / メチル化阻害薬 / NF-kappa B / 転写因子 / NF-kappaB / HIF1 / RNAi / 低酸素応答 / LCM / 低酸素環境 … More Except Principal Investigator 遺伝子 / p53 / 口腔癌 / 細胞周期 / 歯学 / 癌 / 口腔扁平上皮癌 / cell cycle / 口腔がん / シグナル伝達 / エピジェネティクス / 臨床腫瘍学 / チェックポイント / ユビキチンリガーゼ / 薬剤感受性 / 微小管阻害剤 / トランスレーショナルリサーチ / トランスクリプトーム / 機能獲得変異 / 腫瘍微小環境 / tumor budding / 癌微小環境 / Tumor Budding / RAS signaling / genomics / oral cancer / 細胞接着 / translationalresearch / checkpoint / ubiquitinliease / microtubule inhibitor / drug sensitivity / トランスレーショナルリサーチ / 幹細胞 / ワクチン / ALDH1 / がんワクチン / がん幹細胞 / HIF-1 / がん発育先進部 / 化学療法 / EMT / NF-κB/p65 / GLUT-1 / 上皮-間葉転換 / 低酸素 / βカテニン / ゲノム / トランスレーションリサーチ / PARP-1 / PARP-1阻害剤 / CHFR Less

口腔癌における免疫チェックポイント阻害薬の治療効果因子としてのNotch1変異の意義Principal Investigator
- Principal Investigator
  
  荻和弘
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Sapporo Medical University
p53の機能獲得変異は口腔扁平上皮癌の治療標的となり得るか
- Principal Investigator
  
  松田亜沙実
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Sapporo Medical University
遺伝子変異とがん免疫環境は口腔癌の免疫チェックポイント阻害薬の奏効率の指標となるPrincipal Investigator
- Principal Investigator
  
  荻和弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Sapporo Medical University
The estimation of the efficacy of immuno-checkpoint inhibitor in gene mutation for recurrent oral cancerPrincipal Investigator
- Principal Investigator
  
  Ogi Kazuhiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Sapporo Medical University
The elucidation of tumor microenvironment in invasive front of oral cancer and its application to therapy
- Principal Investigator
  
  Hiratsuka Hiroyoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
A novel design of metabolic target therapy in oral cancer cellsPrincipal Investigator
- Principal Investigator
  
  Ogi Kazuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Development of a novel cancer vaccine that targets oral cancer stem cells
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Expression analysis of DKK gene and development of a molecular targeted therapy for oral cancer
- Principal Investigator
  
  SOGABE Yohei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Analysis of the β catenin gene abnormality and therapeutic application for oral cancer.
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Expression analysis of SFRP family genes for development of molecular targeted therapy for oral cancer
- Principal Investigator
  
  SOGABE Yohei
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Analysis of the role of transcription factor in the formation of tumor microvassel in oral cancerPrincipal Investigator
- Principal Investigator
  
  OGI Kazuhiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Functional analysis of CHFR: Diagnostic and therapeutic application for oral squamous cell cancer
- Principal Investigator
  
  TOKINO Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
The analysis of gene induced at tumor angiogenesis in oral cancer and the establishment of molecular target therapyPrincipal Investigator
- Principal Investigator
  
  OGI Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Diagnostic and therapeutic application of cell-cycle checkpoint genes for oral squamous cell cancer.
- Principal Investigator
  
  TOKINO Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
EVALUATION OF GRANDE OF MALLIGNANCY ON THE BASIS OF CELL CYCLE ADHESION MOLECULESIN ORAL SQUAMOUS CELL CARCUNOMA
- Principal Investigator
  
  YAMAGUCHI Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University

[Book] Precision Medicine　2020年12月号　口腔癌に対する免疫療法: 個別化・複合免疫療法の臨床応用に向けての研究2020
- Author(s)
  宮﨑　晃亘, 荻　和弘, 小池　和茂, 岡本　準也, 出張　裕也, 中井　裕美
- Total Pages
  94
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-19K10337
[Book] Anatomy, Kinematics and Diseases2012
- Author(s)
  Nakamori K, Dehari H, Miyazaki A, Ogi K, Anbo N, Shimanishi M, Kaneko T, Hiratsuka H
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] Notch signaling genes and <scp>CD8</scp><sup>+</sup> T‐cell dynamics: Their contribution to immune‐checkpoint inhibitor therapy in oral squamous cell carcinoma: A retrospective study2024
- Author(s)
  Ogi Kazuhiro、Iwamoto Takahiro、Sasaya Takashi、Nishiyama Koyo、Tokura Takaaki、Sasaki Takanori、Dehari Hironari、Arihara Yohei、Murase Kazuyuki、Saito Masato、Someya Masanori、Takada Kohichi、Miyazaki Akihiro
- Journal Title
  
  Cancer Medicine
  
  Volume: 13 Issue: 5
- DOI
  10.1002/cam4.6985
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16160, KAKENHI-PROJECT-22K10197, KAKENHI-PROJECT-21K07680, KAKENHI-PROJECT-23K27794
[Journal Article] DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes2021
- Author(s)
  Hatanaka Yui、Niinuma Takeshi、Kitajima Hiroshi、Nishiyama Koyo、Maruyama Reo、Ishiguro Kazuya、Toyota Mutsumi、Yamamoto Eiichiro、Kai Masahiro、Yorozu Akira、Sekiguchi Shohei、Ogi Kazuhiro、Dehari Hironari、Idogawa Masashi、Sasaki Yasushi、Tokino Takashi、Miyazaki Akihiro、Suzuki Hiromu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20438-20438
- DOI
  10.1038/s41598-021-99736-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19239, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-19K10337, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846
[Journal Article] Prognostic value of CD45Ro＋ T-cell expression in patients with oral squamous cell carcinoma2021
- Author(s)
  Koike Kazushige, Nishiyama Koyo, Dehari Hironari, Ogi Kazuhiro, Sasaki Takanori, Shimizu Shota, Sasaya Takashi, Tsuchihashi Kei, Sonoda Tomoko, Hasegawa Tadashi, Hiratsuka Hiroyoshi, Miyazaki Akihiro.
- Journal Title
  
  Anticancer Res.
  
  Volume: 41(9) Issue: 9 Pages: 4515-4522
- DOI
  10.21873/anticanres.15262
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18675, KAKENHI-PROJECT-19K10337
[Journal Article] Prognostic value of HLA class Ⅰ expression in patients with oral squamous cell carcinoma2020
- Author(s)
  Koike K, Dehari H, Shimizu S, Nishiyama K, Sonoda T, Ogi K, Kobayashi J, Sasaki T, Sasaya T, Tsuchihashi K, Tsukahara T, Hasegawa T, Torigoe T, Hiratsuka H, Miyazaki A
- Journal Title
  
  Cancer Sci
  
  Volume: in press Issue: 5 Pages: 1491-1499
- DOI
  10.1111/cas.14388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10292, KAKENHI-PROJECT-19K10337, KAKENHI-PROJECT-20K18675, KAKENHI-PROJECT-20K18732
[Journal Article] Prognostic value of FoxP3 and CTLA-4 expression in patients with oral squamous cell carcinoma2020
- Author(s)
  Koike Kazushige、Dehari Hironari、Ogi Kazuhiro、Shimizu Shota、Nishiyama Koyo、Sonoda Tomoko、Sasaki Takanori、Sasaya Takashi、Tsuchihashi Kei、Hasegawa Tadashi、Torigoe Toshihiko、Hiratsuka Hiroyoshi、Miyazaki Akihiro
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 8 Pages: e0237465-e0237465
- DOI
  10.1371/journal.pone.0237465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10292, KAKENHI-PROJECT-19K10337, KAKENHI-PROJECT-20K18675
[Journal Article] Chemotherapy after progression on nivolumab is essential for responders with genetic alterations of driver gene: Review of two recurrent/metastatic squamous cell carcinoma patients2020
- Author(s)
  荻　和弘
- Journal Title
  
  Oral Oncology
  
  Volume: 102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10337
[Journal Article] Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of invasion2018
- Author(s)
  清水翔太, 宮﨑晃亘, 園田智子, 小池和茂, 荻　和弘, 小林淳一, 金子　剛, 五十嵐友彦, 上田　愛, 出張裕也, 宮川　明, 長谷川匡, 平塚博義
- Journal Title
  
  PLOS ONE
  
  Volume: 13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15827
[Journal Article] Low-grade mucoepidermoid carcinoma with regional lymph node metastasis: A case report and genetic review of criteria for grading2016
- Author(s)
  中垣貴文, 荻　和弘
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 28 Issue: 2 Pages: 189-192
- DOI
  10.1016/j.ajoms.2015.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670872
[Journal Article] Silencing of GLUT-1 inhibits sensitization of oral cancer cells to cisplatin during hypoxia.2013
- Author(s)
  Shimanishi M, Ogi K, Sogabe Y, Kaneko T, Dehari H, Miyazaki A, Hiratsuka H.
- Journal Title
  
  J Oral Pathol Med.
  
  Volume: 42(5) Issue: 5 Pages: 382-8
- DOI
  10.1111/jop.12028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-24659901
[Journal Article] Suppression of NF-κB/p65 inhibits the proliferation in oral squamous cancer cells.2013
- Author(s)
  Naoki Anbo, Kazuhiro Ogi, Yohei Sogabe, Makoto Shimanishi, Takeshi Kaneko, Hironari Dehari, Akihiro Miyazaki, Hiroyoshi Hiratsuka.
- Journal Title
  
  Journal of Cancer Therapy
  
  Volume: 04 Issue: 04 Pages: 891-897
- DOI
  10.4236/jct.2013.44100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] A case of extensive mandibular osteomyelitis in a patient receiving hemodialysis2010
- Author(s)
  Kazuhiro Ogi
- Journal Title
  
  Asian journal of Oral and Maxillofacial Surgery
  
  Volume: 22巻 Pages: 233-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] A case of extensive mandibular osteomyelitis in a patient receiving hemodialysis2010
- Author(s)
  Ogi K
- Journal Title
  
  Asian J Oral Maxillofac Surg
  
  Volume: 22 Pages: 233-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792022
[Journal Article] CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappa B.2009
- Author(s)
  Kashima L, Toyota M, Mita H, Suzuki H, Ogi K, Tokino T
- Journal Title
  
  Oncogene. 28(29)(有)
  
  Pages: 2643-2643
- Data Source
  KAKENHI-PROJECT-21792022
[Journal Article] CHFR, a potential tumor suppressor, downregulates interleukin-8 via inhibition of NF-kB.2009
- Author(s)
  Kashima L, Toyota M, Mita H, Suzuki H, Idogawa M, Ogi K, Sasaki Y, Tokino T
- Journal Title
  
  Oncogene Vol.28, No.29
  
  Pages: 2643-2653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.2008
- Author(s)
  Sogabe Y, Suzuki H, Toyota M, Ogi K, Imai T, Nojima M, Sasaki Y, Hiratsuka H, Tokino T.
- Journal Title
  
  Int J Oncol. 32(6)
  
  Pages: 1253-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791534
[Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008
- Author(s)
  Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
- Journal Title
  
  Cancer Sci Vol.99, No.5
  
  Pages: 958-966
- NAID
  10024006089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008
- Author(s)
  Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T.
- Journal Title
  
  Cancer Sci. 99(5)
  
  Pages: 958-966
- NAID
  10024006089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791534
[Journal Article] Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.2008
- Author(s)
  Sogabe Y, Suzuki H, Toyata M, Ogi K, Imai T, Nojima M, Sasaki Y, Hiratsuka H, Tokino T
- Journal Title
  
  Int J Oncology Vol.32, No.6
  
  Pages: 1253-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.2007
- Author(s)
  Ricci MS, Kim SH, Ogi K
- Journal Title
  
  Cancer Cell 12(1)
  
  Pages: 66-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] NOTCHシグナル伝達系の遺伝子変異は再発口腔癌における免疫チェックポイント阻害剤の治療効果に影響する.2023
- Author(s)
  荻　和弘，岩本空大，笹谷　聖，都倉尭明，佐々木敬則，出張裕也，平塚博義，宮﨑晃亘.
- Organizer
  第47回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-22K10197
[Presentation] 口腔癌細胞株を用いたNotchシグナル異常とがん免疫環境との関連性の解明.2023
- Author(s)
  岩本空大, 荻和弘, 西山廣陽, 宮崎晃亘.
- Organizer
  第77回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-22K10197
[Presentation] Predictive assesment of ctDNA monitoring of tongue carcinoma patient with nivolumab responder2022
- Author(s)
  荻　和弘、岩本空大、西山廣陽、高田弘一、染谷正則、宮﨑晃亘
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] Predictive assesment of ctDNA monitoring of tongue carcinoma patient with nivolumab responder2022
- Author(s)
  荻　和弘、岩本空大、西山廣陽、高田弘一、染谷正則、宮﨑晃亘
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K10197
[Presentation] 再発口腔癌におけるPD-L1, CD8の発現の意義とNOTCHシグナルを介したがん免疫機構の解析2022
- Author(s)
  荻　和弘，岩本空大，笹谷　聖，小池和茂，岡本準也，金子　剛，佐々木敬則，出張裕也，中井裕美，宮﨑晃亘
- Organizer
  第46回日本頭頸部癌学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K10197
[Presentation] 再発口腔癌におけるPD-L1, CD8の発現の意義とNOTCHシグナルを介したがん免疫機構の解析2022
- Author(s)
  荻　和弘，岩本空大，笹谷　聖，小池和茂，岡本準也，金子　剛，佐々木敬則，出張裕也，中井裕美，宮﨑晃亘
- Organizer
  第46回日本頭頸部癌学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] 全エクソーム解析によるがん遺伝子変異と臨床効果との関連性が示唆された舌癌の１例2021
- Author(s)
  荻　和弘、岩本空大、笹谷　聖、西山廣陽、岡本準也、金子　剛、佐々木敬則、出張裕也、中井裕美、宮﨑晃亘
- Organizer
  第40回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] 口腔扁平上皮癌における腫瘍浸潤リンパ球の局在と予後との関連性についての研究2020
- Author(s)
  小池和茂、出張裕也、荻　和弘、西山廣陽、佐々木敬則、土橋　恵、笹谷　聖、中井裕美、岡本準也、宮﨑晃亘
- Organizer
  第65回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] 再発または遠隔転移を有する口腔癌に対しニボルマブ投与は遺伝子変異が指標となるか2020
- Author(s)
  荻　和弘、小林淳一、西山廣陽、小池和茂、高田弘一、染谷正則、宮﨑晃亘
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] Prognostic impact of HLA class I expression and its association with CD8 T-cell density in patients with oral squamous cell carcinoma2020
- Author(s)
  Koike K, Dehari H, Ogi K, Shimizu S, Nishiyama K, Sonoda T, Sasaki T, Sasaya T, Tsuchihashi K, Hasegawa T, Torigoe T, Hiratsuka H, Miyazaki A
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] IgG関連疾患が疑われる頸部リンパ節腫大の1症例2019
- Author(s)
  千種　達也、荻　和弘ら
- Organizer
  第45回日本口腔外科学会北日本支部学術集会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] 口腔扁平上皮癌における制御性T細胞の発現に関する免疫組織化学的検討2019
- Author(s)
  小池和茂、荻　和弘ら
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K10337
[Presentation] がん微小環境において解糖系阻害薬を併用した放射線増感効果に関する研究.2016
- Author(s)
  荻　和弘
- Organizer
  第61回日本口腔外科学会総会・学術大会
- Place of Presentation
  幕張メッセ国際会議場・国際展示場（千葉県千葉市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26670872
[Presentation] DNA double-strand breaks in hypoxic but not in normoxicconditions determine different radiosensitivity of tumors2015
- Author(s)
  荻　和弘
- Organizer
  アメリカ癌学会
- Place of Presentation
  米国・フィラデルフィア
- Year and Date
  2015-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670872
[Presentation] DNA double strand breaks in hypoxic but not in normoxic conditions determine different radiosensitivity of tumors in oral squamous cell carcinoma2015
- Author(s)
  荻　和弘
- Organizer
  アメリカ癌学会
- Place of Presentation
  米国・フィラデルフィア
- Year and Date
  2015-04-21
- Data Source
  KAKENHI-PROJECT-26670872
[Presentation] 低酸素環境下でのHIFの活性化とGLUT-1ノックダウンによる細胞死の誘導2012
- Author(s)
  荻和弘
- Organizer
  第１０回がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Sliencing of GLUT1 inhibits sensitizes oral cancer cells to CDDP during hypixia2012
- Author(s)
  荻　和弘
- Organizer
  第71回　日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] 低酸素環境下でのHIFの活性化とNF-kappaB　経路の検討2012
- Author(s)
  荻和弘
- Organizer
  第57回　日本口腔外科学会総会・学術大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Silencing of GLUT1 inhibits sensitizes oral cancer cells to CDDP during hypoxia2012
- Author(s)
  荻和弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Silencing of GLUT1 inhibits sensitizes oral cancer cells to CDDP during hypoxia2012
- Author(s)
  Kazuhiro Ogi, Makoto Shimanishi, Takeshi Kaneko, Hironari Dehari, Akihiro Miyazaki, Hiroyoshi Hiratsuka.
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Identification of epigenetic change of genes that mediates hypoxic adaptation using HIF regulated cDNA plate array2011
- Author(s)
  Kazuhiro Ogi, et al
- Organizer
  第70回日本癌学会総会・学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 関連診療科(脳神経外科、耳鼻咽喉科、形成外科)との合同手術により救命し得た舌癌頸部再発の1例2011
- Author(s)
  荻和弘, 他
- Organizer
  第37回日本口腔外科学会北日本地方会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Analysis of cDNA plate array between CDDP sensitive and CDDP resistant. Oral squamous cancer cell line ; HIF-1 can regulate NF-κB under hypoxia2011
- Author(s)
  Naoki Anbo, Makoto Shimanishi, Kazuhiro Ogi, Hiroyoshi Hiratsuka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Identification of epigenetic change of genes that mediates hypoxic adaptation using HIF regulated cDNA plate array.2011
- Author(s)
  Kazuhiro Ogi, Makoto Shimanishi, Naoki Anbo, Tsuyoshi Kaneko, Yohei sogabe, Hironari Dahari, Hiroyoshi Hiratsuka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌における癌低酸素領域での血管新生因子に関する臨床的意義2010
- Author(s)
  荻和弘
- Organizer
  日本癌学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌における低酸素領域での血管新生因子に関する臨床的意義2010
- Author(s)
  荻和弘
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21792022
[Presentation] 口腔癌における癌低酸素領域での血管新生因子に関する臨床的意義2010
- Author(s)
  荻和弘、仲盛健治、宮崎晃亘、島西真琴、安保直樹、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 癌低酸素領域での血管新生因子およびリンパ管新生因子の発現の検討2010
- Author(s)
  荻和弘、仲盛健治, ら
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21792022
[Presentation] Clinical Significance of Cortactin and Cyclin D1 Expression in Squamous Cell Carcinomas of the Tongue2010
- Author(s)
  Kenji Nakamori, Hironari Dehari, Takashi Imai, Akihiro Miyazaki, Kazuhiro Ogi, Naoki Anbo, Makoto Shimanishi, Hiroyoshi Hiratsuka
- Organizer
  20th European Association for Cranio-Maxillo-facial Surgery
- Place of Presentation
  ベルギー
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌に対するサバイビン2Bペプチドワクチン療法の第I臨床試験2010
- Author(s)
  宮崎晃亘、小林淳一、鳥越俊彦、廣橋良彦、山本崇、道振義貴、浅沼広子、荻和弘、山口晃、佐藤昇志、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] hMHL1, hMSH2の口腔扁平上皮癌の抗癌剤耐性獲得への関与に関する研究2010
- Author(s)
  安保直樹、島西真琴、荻和弘、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌における癌低酸素領域での血管新生因子およびリンパ管新生因子の発現の臨床的意義2009
- Author(s)
  荻和弘、仲盛健治, ら
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21792022
[Presentation] 口腔癌における癌低酸素領域での血管新生因子に関する臨床的検討2008
- Author(s)
  荻和弘、仲盛健治ら
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] Clinical investigation of the roles of angiogenic factors in hypoxic regions of oral cancer2008
- Author(s)
  荻和弘
- Organizer
  アメリカ癌学会2008年年次総会
- Place of Presentation
  アメリカ(サンディエゴ)
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] 口腔癌は克服できたか-癌浸潤様式4C、4D型症例の治療成績2008
- Author(s)
  宮崎晃亘、山口晃、荻和弘ら
- Organizer
  日本癌治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] 口腔がんにおける低酸素領域での血管新生因子に関する臨床検討2008
- Author(s)
  荻和弘、仲盛健治ら
- Organizer
  日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] Clinical investigation of the roles of angiogenic factors in hypoxic regions of oral cancer2008
- Author(s)
  Ogi K, Kenji N.
- Organizer
  アメリカ癌学会総会
- Place of Presentation
  サンディエゴ、米国
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] El-deiry ; Silencing of NF-kappaB p65 subunit inhibits HIF-1 alpha expression during hypoxia and sensitizing HCT116 colon cancer cells to CPT11 but not TRAIL2007
- Author(s)
  Ogi K. Wafik S
- Organizer
  アメリカ癌学会総会
- Place of Presentation
  ロスアンゼルス、米国
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] Silencing of the NF-kB p65 subunit inhibits HIF1-alpha expression during hypoxia and sensitizes HCT116 colon cancer cells to CPT11 but not TRAIL2007
- Author(s)
  荻和弘
- Organizer
  アメリカ癌学会2007年年次総会
- Place of Presentation
  アメリカ(ロサンゼルス)
- Year and Date
  2007-04-15
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] 口腔扁平上皮癌におけるRAS関連遺伝子の異常の解析2007
- Author(s)
  今井崇、荻和弘ら
- Organizer
  日本口腔外科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] 口腔扁平上皮癌におけるRAS関連遺伝子のジェネティックおよびエピジェネティックな解析の解析2007
- Author(s)
  今井崇、秋野公臣、荻和弘ら
- Organizer
  日本口腔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19791534
[Presentation] Immunotherapeutic benefit of α-interferon in survivin2B-derived peptide vaccination for patients with oral cancer.
- Author(s)
  Akihiro　Miyazaki,　Junichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Takanori Sasaki, Sho Miyamoto, Kazuhiro Ogi, Hironari Dehari, Noriyuki Sato, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Identification of long non-coding RNAs potentially involved in oral squamous cell carcinoma.
- Author(s)
  Koyo Nishiyama, Reo Maruyama, Kosuke Takeda, Takahumi Nakagaki, Takeshi Niinuma, Kazuhiro Ogi, Hironari Dehari, Akihiro Miyazaki, Masahiro Kai, Yasushi Sasaki, Takeshi Tokino, Hiromu Suzuki, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 family target
- Author(s)
  Kousuke Takeda，Yasushi Sasaki , Takafumi Nakagaki, Miyuki Tamura, Masashi Idogawa , Kazuhiro Ogi, Hiroyoshi Hiratsuka, Takashi Tokino
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Wnt/β-catenin signaling pathway directly controls hypoxia induced epithelial mesenchymal transition in oral cancer
- Author(s)
  Takeshi Kaneko, Hironari Dehari, Kazuhiro Ogi, Kousuke Takeda, Junichi Kobayashi, Akihiro Miyazaki, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] 口腔がんに対するサバイビン２Bペプチドワクチン・インターフェロン併用療法の臨床試験
- Author(s)
  宮崎晃亘、小林淳一、鳥越俊彦、廣橋良彦、佐々木敬則、宮本昇、出張裕也、荻和弘、佐藤昇志、平塚博義
- Organizer
  第５２回日本癌治療学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] A next-Generation Sequencing Screen for Mutational Hotspots in 50 Cancer-Related Genes using Semiconductor Sequencer.
- Author(s)
  Takafumi　Nakagaki, Yasushi Sasaki, Masashi Idogawa, Kousuke Takeda, Miyuki Tamura, Tomoko Ohashi, Kazuhiro Ogi, Hiroyoshi Hiratsuka, Takashi Tokino
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901

1. HIRATSUKA Hiroyoshi (50165180)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. MIYAZAKI Akihiro (10305237)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. SOGABE Yohei (50468104)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. TOKINO Takashi (40202197)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. DEHARI Hironari (00381260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. NAKAMORI Kenji (60295334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. KOBAYASHI Jyunichi (80404739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 西山廣陽 (60749563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. SASAKI Takanori (50548732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAMOTO Takashi (50448594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SHIMANISHI Makoto (10516561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. MICHIFURI Yoshitaka (00457722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAGUCHI Akira (10210353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 上田愛 (80568105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 宮本昇 (80749565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松田亜沙実 (30897533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 佐々木泰史 (70322328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 笹谷聖 (10815715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. 岩本空大 (90894048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. 土橋恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 畠中柚衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 小池和茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogi Kazuhiro 荻 和弘

荻 和弘 オギ カズヒロ

OGI Kazuhiro 荻 和弘

Research Projects

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口腔癌における免疫チェックポイント阻害薬の治療効果因子としてのNotch1変異の意義Principal Investigator

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遺伝子変異とがん免疫環境は口腔癌の免疫チェックポイント阻害薬の奏効率の指標となるPrincipal Investigator

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The estimation of the efficacy of immuno-checkpoint inhibitor in gene mutation for recurrent oral cancerPrincipal Investigator

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A novel design of metabolic target therapy in oral cancer cellsPrincipal Investigator

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Analysis of the role of transcription factor in the formation of tumor microvassel in oral cancerPrincipal Investigator

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The analysis of gene induced at tumor angiogenesis in oral cancer and the establishment of molecular target therapyPrincipal Investigator

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Ogi Kazuhiro 荻和弘

荻和弘オギカズヒロ

OGI Kazuhiro 荻和弘

[Book] Precision Medicine　2020年12月号　口腔癌に対する免疫療法: 個別化・複合免疫療法の臨床応用に向けての研究2020