TAKEDA YOSHITO 武田吉人

Researcher Number	40452388
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 大阪大学, 大学院医学系研究科, 准教授 2020 – 2021: 大阪大学, 医学系研究科, 准教授 2018 – 2019: 大阪大学, 医学系研究科, 講師 2016 – 2017: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 大学院医学系研究科, 助教 … More 2012 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2011: 大阪大学, 大学院・医学系研究科, 助教 2010 – 2011: 大阪大学, 医学系・研究科, 助教 2008 – 2011: 大阪大学, 医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Basic Section 52040:Radiological sciences-related / Biomedical engineering/Biological material science
Keywords	Principal Investigator エクソソーム / プロテオミクス / バイオマーカー / COPD / バイオインフォマティクス / マルチオミクス / 間質性肺炎 / PF-ILD / システムバイオロジー / PRISM … More / AI / IPF / PPF / 呼吸器疾患 / オミクス / 慢性炎症性呼吸器疾患 / トランスクリプトーム / メタボローム / 創薬開発 / トランスオミクス / 個別化医療 / exosome / 喘息 / proteomics / 閉塞性肺疾患 / adiponectin / imaging / イメージング / ＣＯＰＤ / 超編極ガスXe-MRI / CT / アディポネクチン / 上皮細胞 / CD9 / 肺線維症 / CD151 / インテグリン、CD9 / テトラスパニン / 特発性肺線維症 … More Except Principal Investigator バイオマーカー / プロテオミクス / エクソソーム / テトラスパニン / 免疫療法 / ペプチドワクチン / 癌免疫療法 / 肺癌 / WT1 / 細胞外小胞 / LAM / リンパ脈管筋腫症 / 癌抗原 / マクロファージ / CD9 / 癌ワクチン / 癌免疫 / 臍帯血 / シングルセルレパトア解析 / 抗GM-CSF抗体 / 病原性抗体 / 自己免疫性肺胞蛋白症 / 気管支喘息 / アミロイドーシス / 免疫染色 / 希少疾患 / 肺アミロイドーシス / 治療効果予測 / SUVmax / FDG集積 / 糖代謝 / 癌の免疫微小環境 / FDG-PET/CT / 予後予測 / 治療効果判定 / 免疫チェックポイント阻害剤 / FDG-PET / 呼吸器難病 / miRNA / 腫瘍 / 小胞輸送 / Lymphangioleiomyomatosis / TSC / 結節性硬化症 / 間質性肺炎 / 肺線維症疾患モデルマウス / 特発性肺線維症 / 肺線維症 / 病態モデル / MRS / 生体磁気共鳴計測 / 超偏極希ガス / 超偏極 / 前臨床評価系 / 慢性閉塞性肺疾患 / イメージング / 難治性肺疾患 / 新薬探索 / 前臨床評価 / 肺機能診断 / MRI / 超偏極キセノン / 癌免疫動態 / 胸腺腫瘍 / 胸腺悪性腫瘍 / 胸部悪性腫瘍 / 肺がん / がんワクチン / 胸部悪性疾患 / ヘルパー / ヘルパーペプチド / ヘルパーTリンパ球 / Th17 / CTL / T細胞レセプター / 悪性腫瘍 / 免疫治療 / ラフト / CD14 / スタチン / COPD / 胸腺腫 / CD151 / リンパ管新生 / 血管新生 / 炎症 / LPS / 閉塞性肺疾患 Less

個別化医療を目指した進行性肺線維症の病態解明と新規治療法開発Principal Investigator
- Principal Investigator
  
  武田吉人
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Osaka
エクソソームのマルチオミクスが紐解く気管支喘息の新規BM開発と病態解明
- Principal Investigator
  
  平田陽彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka University
自己免疫性肺胞蛋白症の末梢血B細胞シングルセル解析による病態解明と新規治療開発
- Principal Investigator
  
  二見真史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka University
Treatment response and prognosis prediction of immune checkpoint inhibitors by FDG-PET/CT: A Japanese multicenter prospective study
- Principal Investigator
  
  北島一宏
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hyogo Medical University
次世代プロテオミクスが紐解く個別化医療に有用なPF-ILDの新規BM開発Principal Investigator
- Principal Investigator
  
  武田吉人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka University
最新プロテオミクスによる肺アミロイドーシスのバイオマーカーの探索
- Principal Investigator
  
  滝本宜之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  NHO Kinki Chuo Chest Medical Center(Clinical Research Center)
Identification of novel biomarkers for lymphangioleiomyomatosis from extracellular vesicles by comprehensive approach .
- Principal Investigator
  
  Takimoto Takayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  NARIONAL HOSPITAL ORGANIZATION KINKI-CHUO CHEST MEDICAL CENTER
Discovery of novel BM and pathogenesis in COPD by trans-omicsPrincipal Investigator
- Principal Investigator
  
  Takeda Yoshito
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka University
Exploration of innovative biomarkers in pulmonary fibrosis by quantitative proteomics of exosomes
- Principal Investigator
  
  HIRATA HARUHIKO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Elucidation of the roles of tetraspanins and vesicle transport in the tumor progression of lymphanigoleiomyomatosis.
- Principal Investigator
  
  Takimoto Takayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  NARIONAL HOSPITAL ORGANIZATION KINKI-CHUO CHEST MEDICAL CENTER
  Osaka University
Analysis of immune response against cancer, which may lead to establishment of WT1 peptide-based immunotherapy for the conventional treatment-resistant malignancies in the respiratory medicine field
- Principal Investigator
  
  OKA YOSHIHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Proteomics of peripheral exosome identifies novel biomarkers for COPDPrincipal Investigator
- Principal Investigator
  
  Takeda Yoshito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Role of adiponectin in COPDPrincipal Investigator
- Principal Investigator
  
  TAKEDA Yoshito
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
テトラスパニンに作用するＣＯＰＤ治療薬の探索
- Principal Investigator
  
  立花功
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of WT1 peptide-based immunotherapy for inoperable thoracic malignant tumors, and analysis of immunodynamics of the novel therapy
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of preclinical system based on pulmonary functional imaging by hyperpolarized Xe MRI
- Principal Investigator
  
  Kimura Atsuomi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University
Cancer antigen WT1-targeting peptide vaccine therapy for lung cancer
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Functional analysis of tetraspanins(CD9, CD151) in lung fibrosisPrincipal Investigator
- Principal Investigator
  
  TAKEDA Yoshito
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Mechanisms of lung inflammation in tetraspanin-knockout mice
- Principal Investigator
  
  TACHIBANA Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Role or tetraspanins in angiogenesis and lymphangiogenesis
- Principal Investigator
  
  TAKAHASHI Ryo, 川瀬一郎
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of WT1 peptide cancer vaccine targeting lung cancer
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University

[Book] Efficacy and safety of pirfenidone for idiopathic pulmonary fibrosis.2014
- Author(s)
  Takeda Y, Tsujino K, Kijima T, Kumanogoh A.
- Total Pages
  8
- Publisher
  Patient Preference and Adherence
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer2024
- Author(s)
  Hirai Takashi、Naito Yujiro、Koyama Shohei、Aoshi Taiki、Villa Jordan Kelly、Yamashita Kazuo、Enokida Tomohiro、Hoshi Yuta、Matsuura Kazuto、Tahara Makoto、Takamatsu Hyota、Takeda Yoshito、Inohara Hidenori、Kumanogoh Atsushi
- Journal Title
  
  JCI Insight
  
  Volume: 9 Issue: 3 Pages: 1-2
- DOI
  10.1172/jci.insight.166349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-21K07252, KAKENHI-PROJECT-22K16361
[Journal Article] Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology2024
- Author(s)
  Hanako Yoshimura et al.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 153 Issue: 5 Pages: 1268-1281
- DOI
  10.1016/j.jaci.2023.12.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2494, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-20K17180, KAKENHI-PROJECT-22K16361
[Journal Article] A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth2023
- Author(s)
  Miyake Kotaro、Costa Cruz Pedro Henrique、Nagatomo Izumi、Kato Yuki、Motooka Daisuke、Satoh Shingo、Adachi Yuichi、Takeda Yoshito、Kawahara Yukio、Kumanogoh Atsushi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 7 Pages: 112688-112688
- DOI
  10.1016/j.celrep.2023.112688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12109, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-23K27267
[Journal Article] Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity2023
- Author(s)
  Japan COVID-19 Task Force
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 5 Pages: 753-767
- DOI
  10.1038/s41588-023-01375-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16624, KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-23K11300, KAKENHI-PROJECT-21K09068, KAKENHI-PROJECT-22K15493, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K27671
[Journal Article] A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients2023
- Author(s)
  S?ndergaard Jonas N?rskov、Tulyeu Janyerkye、Edahiro Ryuya、Shirai Yuya、Yamaguchi Yuta、Murakami Teruaki、Morita Takayoshi、Kato Yasuhiro、Hirata Haruhiko、Takeda Yoshito、Okuzaki Daisuke、Sakaguchi Shimon、Kumanogoh Atsushi、Okada Yukinori、Wing James Badger
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 4
- DOI
  10.1073/pnas.2217902120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-21J12329, KAKENHI-PROJECT-23K27671
[Journal Article] Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease2023
- Author(s)
  Niitsu Takayuki、Fukushima Kiyoharu、Komukai Sho、Takata So、Abe Yuko、Nii Takuro、Kuge Tomoki、Iwakoshi Shinichi、Shiroyama Takayuki、Miyake Kotaro、Tujino Kazuyuki、Tanizaki Satoshi、Iwahori Kota、Hirata Haruhiko、Miki Keisuke、Yanagawa Masahiro、Takeuchi Noriyuki、Takeda Yoshito、Kida Hiroshi、Kumanogoh Atsushi
- Journal Title
  
  RMD Open
  
  Volume: 9 Issue: 1 Pages: e002667-e002667
- DOI
  10.1136/rmdopen-2022-002667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08194, KAKENHI-PROJECT-21K16118, KAKENHI-PROJECT-19K08650
[Journal Article] Tumor-derived semaphorin 4A improves PD-1 blocking antibody efficacy by enhancing CD8+ T-cell cytotoxicity and proliferation2023
- Author(s)
  Naito Y et al
- Journal Title
  
  Science Advances
  
  Volume: - Issue: 20 Pages: 1-2
- DOI
  10.1126/sciadv.ade0718
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07252, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-23K06696, KAKENHI-PROJECT-22K16361, KAKENHI-PROJECT-23K27671
[Journal Article] Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells2022
- Author(s)
  Yamaguchi Yuta et al.
- Journal Title
  
  JCI Insight
  
  Volume: 7 Issue: 22 Pages: 393-393
- DOI
  10.1172/jci.insight.163347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-21J12329, KAKENHI-PROJECT-19K08650
[Journal Article] Peripheral T cell cytotoxicity predicts the efficacy of anti-PD-1 therapy for advanced non-small cell lung cancer patients2022
- Author(s)
  Iwahori Kota、Uenami Takeshi、Yano Yukihiro、Ueda Toshihiko、Tone Mari、Naito Yujiro、Suga Yasuhiko、Fukushima Kiyoharu、Shiroyama Takayuki、Miyake Kotaro、Koyama Shohei、Hirata Haruhiko、Nagatomo Izumi、Kida Hiroshi、Mori Masahide、Takeda Yoshito、Kumanogoh Atsushi、Wada Hisashi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 393-393
- DOI
  10.1038/s41598-022-22356-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-19K08650
[Journal Article] CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis by proteomics of serum extracellular vesicles.2022
- Author(s)
  Futami Y, Takeda Y, KobaT, Narumi R, Nojima Y, Ito M, Nakayama M, Ishida M,Yoshimura H, Naito Y, Fukushima K, Takimoto T, Edahiro R, Matsuki T, Nojima S, Hirata H, Koyama S, Iwahori K, Nagatomo I, Shirai Y, Suga Y, Satoh S, Futami S, Miyake K, Shiroyama T, Inoue Y, Adachi J, Tomonaga T, Ueda K, Kumanogoh A.
- Journal Title
  
  International immunology
  
  Volume: - Issue: 6 Pages: 1-1
- DOI
  10.1093/intimm/dxac009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08642, KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-20K15422, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-22K08299, KAKENHI-PROJECT-20K17180
[Journal Article] Impact of the Treatment Line on the Risks and Benefits of Immune Checkpoint Inhibitors in Patients With Non-Small Cell Lung Cancer and Interstitial Lung Disease2022
- Author(s)
  Matsumoto Kinnosuke、Shiroyama Takayuki、Yamamoto Yuji、Miyake Kotaro、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Chest
  
  Volume: 162 Issue: 1 Pages: e67-e69
- DOI
  10.1016/j.chest.2022.02.053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-19K08650
[Journal Article] Quantitative evaluation of emphysema for predicting immunotherapy response in patients with advanced non-small-cell lung cancer2022
- Author(s)
  Noda Yoshimi、Shiroyama Takayuki、Masuhiro Kentaro、Amiya Saori、Enomoto Takatoshi、Adachi Yuichi、Hara Reina、Niitsu Takayuki、Naito Yujiro、Miyake Kotaro、Koyama Shohei、Hirata Haruhiko、Nagatomo Izumi、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1332-1341
- DOI
  10.1038/s41598-022-13131-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component2022
- Author(s)
  Shirai Y, Nakanishi Y, Suzuki A, Konaka H, Nishikawa R, Sonehara K, Namba S, Tanaka H, Masuda T, Yaga M, Satoh S, Izumi M, Mizuno Y, Jo T, Maeda Y, Nii T, Oguro-Igashira E, Morisaki T, Kam, Nakayamada S, Nishigori C, Tanaka Y, Takeda Y, Yamamoto K, Kumanogoh A, Okada Y, The Biobank Japan Project
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 9 Pages: 1301-1312
- DOI
  10.1136/annrheumdis-2022-222460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-19K08650
[Journal Article] Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-192022
- Author(s)
  Kawasaki Takahiro、Takeda Yoshito、Edahiro Ryuya、Shiroyama Takayuki、Hirata Haruhiko、Adachi Jun、Okada Yukinori、Kumanogoh Atsushi
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 393-393
- DOI
  10.1186/s41232-022-00243-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-20K17180, KAKENHI-PROJECT-22K16193, KAKENHI-PROJECT-21J12329, KAKENHI-PROJECT-19K08650
[Journal Article] A case of synchronous triple autoimmune disorders secondary to thymoma: Pure red cell aplasia, Good's syndrome, and thymoma-associated multi-organ autoimmunity2022
- Author(s)
  Nakagawa Yuta、Matsumoto Kinnosuke、Yamamoto Makoto、Hirata Haruhiko、Shiroyama Takayuki、Miyake Kotaro、Yamamoto Yuji、Kuge Tomoki、Yoneda Midori、Naito Yujiro、Suga Yasuhiko、Fukushima Kiyoharu、Koyama Shohei、Iwahori Kota、Nagatomo Izumi、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Respiratory Medicine Case Reports
  
  Volume: 36 Pages: 101619-101619
- DOI
  10.1016/j.rmcr.2022.101619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Impact of treatment line on risks and benefits of immune checkpoint inhibitor in patients with advanced non-small cell lung cancer and interstitial lung disease: a systematic review and meta-analysis of cohort studies2022
- Author(s)
  Matsumoto Kinnosuke、Shiroyama Takayuki、Kuge Tomoki、Miyake Kotaro、Yamamoto Yuji、Yoneda Midori、Yamamoto Makoto、Naito Yujiro、Suga Yasuhiko、Fukushima Kiyoharu、Koyama Shohei、Iwahori Kota、Hirata Haruhiko、Nagatomo Izumi、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 11 Issue: 9 Pages: 1835-1846
- DOI
  10.21037/tlcr-22-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Longitudinal alterations of the gut mycobiota and microbiota on COVID-19 severity2022
- Author(s)
  Maeda Yuichi、Motooka Daisuke、Kawasaki Takahiro、Oki Hiroya、Noda Yoshimi、Adachi Yuichi、Niitsu Takayuki、Okamoto Shota、Tanaka Kentaro、Fukushima Kiyoharu、Amiya Saori、Hara Reina、Oguro-Igashira Eri、Matsuki Takanori、Hirata Haruhiko、Takeda Yoshito、Kida Hiroshi、Kumanogoh Atsushi、Nakamura Shota、Takeda Kiyoshi
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 22 Issue: 1 Pages: 572-572
- DOI
  10.1186/s12879-022-07358-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08505, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-21H05043, KAKENHI-PROJECT-20K20595
[Journal Article] Leucine-rich a-2 glycoprotein as a potential biomarker of idiopathic multicentric Castleman disease with pulmonary involvement: a single-center case-control study from Japan2022
- Author(s)
  Takata So、Takeda Yoshito、Hirata Haruhiko、Shirai Yuya、Morita Takayoshi、Futami Yu、Naito Yujiro、Masuhiro Kentaro、Shiroyama Takayuki、Miyake Kotaro、Naka Tetsuji、Kumanogoh Atsushi
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 14 Issue: 5 Pages: 1332-1341
- DOI
  10.21037/jtd-21-1973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer2022
- Author(s)
  Masuhiro Kentaro、Tamiya Motohiro、Fujimoto Kosuke
- Journal Title
  
  JCI Insight
  
  Volume: 1 Issue: 9 Pages: 1-1
- DOI
  10.1172/jci.insight.157915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-21K07252, KAKENHI-PROJECT-21K07112, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-22H00477, KAKENHI-PROJECT-21H03538, KAKENHI-PROJECT-21K19495
[Journal Article] Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres.2021
- Author(s)
  Koba, Takeda, Narumi, Shiromizu, Nojima, Ito, Kuroyama, Futami, Takimoto, Matsuki, Edahiro, Nojima, Hayama, Fukushima, Hirata, Koyama, Iwahori, Nagatomo, Suzuki, Shirai, Murakami, Nakanishi, Nakatani, Suga, Miyake, Shiroyama, Kida, Sasaki, Ueda, Mizuguchi, Adachi, Tomonaga, Kumanogoh
- Journal Title
  
  ERJ open research.
  
  Volume: 7(1) Issue: 1 Pages: 00658-2020
- DOI
  10.1183/23120541.00658-2020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08642, KAKENHI-PROJECT-20K15422, KAKENHI-PROJECT-20K17180, KAKENHI-PROJECT-18K17923, KAKENHI-PROJECT-19K16557, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-19K08650
[Journal Article] Impact of treatment timing and sequence of immune checkpoint inhibitors and anti-angiogenic agents for advanced non-small cell lung cancer: A systematic review and meta-analysis2021
- Author(s)
  Matsumoto Kinnosuke、Shiroyama Takayuki、Kuge Tomoki、Miyake Kotaro、Yamamoto Yuji、Yoneda Midori、Yamamoto Makoto、Naito Yujiro、Suga Yasuhiko、Fukushima Kiyoharu、Koyama Shohei、Iwahori Kota、Hirata Haruhiko、Nagatomo Izumi、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Lung Cancer
  
  Volume: 162 Pages: 175-184
- DOI
  10.1016/j.lungcan.2021.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Cytomegalovirus infection in critically ill patients with COVID-192021
- Author(s)
  Niitsu Takayuki、Shiroyama Takayuki、Hirata Haruhiko、Noda Yoshimi、Adachi Yuichi、Enomoto Takatoshi、Hara Reina、Amiya Saori、Uchiyama Akinori、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Journal of Infection
  
  Volume: 83 Issue: 4 Pages: 496-522
- DOI
  10.1016/j.jinf.2021.07.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Predicting recurrence of respiratory failure in critically ill patients with COVID-19: A preliminary study2021
- Author(s)
  Adachi Yuichi、Shiroyama Takayuki、Yamaguchi Yuta、Murakami Teruaki、Hirata Haruhiko、Amiya Saori、Niitsu Takayuki、Noda Yoshimi、Hara Reina、Enomoto Takatoshi、Morita Takayoshi、Kato Yasuhiro、Uchiyama Akinori、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Journal of Infection
  
  Volume: 82 Issue: 5 Pages: e33-e35
- DOI
  10.1016/j.jinf.2021.01.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-19K08650
[Journal Article] Greater reductions in blood flow after anti-angiogenic treatment in non-small cell lung cancer patients are associated with shorter progression-free survival2021
- Author(s)
  Katayama Daisuke、Yanagawa Masahiro、Matsunaga Keiko、Watabe Hiroshi、Watabe Tadashi、Kato Hiroki、Kijima Takashi、Takeda Yoshito、Kumanogoh Atsushi、Shimosegawa Eku、Hatazawa Jun、Tomiyama Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-2
- DOI
  10.1038/s41598-021-86405-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese2020
- Author(s)
  Shirai Yuya、Honda Suguru、Ikari Katsunori、Kanai Masahiro、Takeda Yoshito、Kamatani Yoichiro、Morisaki Takayuki、Tanaka Eiichi、Kumanogoh Atsushi、Harigai Masayoshi、Okada Yukinori
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 79 Issue: 10 Pages: 1305-1309
- DOI
  10.1136/annrheumdis-2020-217256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Pulmonary metastases of lung adenocarcinoma mimicking COVID-19 pneumonia2020
- Author(s)
  Shiroyama Takayuki、Hirata Haruhiko、Nagatomo Izumi、Takeda Yoshito、Kumanogoh Atsushi
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 12 Issue: 10 Pages: 6125-6126
- DOI
  10.21037/jtd-20-2393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-18H05282
[Journal Article] Integrative Analysis Reveals Common and Unique Roles of Tetraspanins in Fibrosis and Emphysema2020
- Author(s)
  Tripathi Lokesh P.、Itoh Mari N.、Takeda Yoshito、Tsujino Kazuyuki、Kondo Yasushi、Kumanogoh Atsushi、Mizuguchi Kenji
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 11 Pages: 1-2
- DOI
  10.3389/fgene.2020.585998
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650
[Journal Article] Metabolomic analysis of fibrotic mice combined with public RNA‐Seq human lung data reveal potential diagnostic biomarker candidates for lung fibrosis2020
- Author(s)
  Nojima Yosui、Takeda Yoshito、Maeda Yohei、Bamba Takeshi、Fukusaki Eiichiro、Itoh Mari N.、Mizuguchi Kenji、Kumanogoh Atsushi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 10 Issue: 11 Pages: 2427-2436
- DOI
  10.1002/2211-5463.12982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-20K15422
[Journal Article] Monitoring Antibody Binding to T Cells in a Pembrolizumab-Treated Patient With Lung Adenocarcinoma on Hemodialysis2019
- Author(s)
  Akio Osa, Takeshi Uenami, Yujiro Naito, Haruhiko Hirata, Shohei Koyama, Takayuki Takimoto, Takayuki Shiroyama, Shinji Futami, Saeko Nakatsubo, Nobuhiko Sawa, Yukihiro Yano, Izumi Nagatomo, Yoshito Takeda, Masahide Mori, Hiroshi Kida, Atsushi Kumanogoh
- Journal Title
  
  Thorac Cancer
  
  Volume: 11 Issue: 11 Pages: 2183-2187
- DOI
  10.1111/1759-7714.13197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-16K09537
[Journal Article] A lung abscess caused by secondary syphilis - the utility of polymerase chain reaction techniques in transbronchial biopsy: a case report.2019
- Author(s)
  Futami S, Takimoto T, Nakagami F, Satoh S, Hamaguchi M, Kuroyama M, Miyake K, Koyama S, Iwahori K, Hirata H, Nagatomo I, Takeda Y, Kida H, Kumanogoh A.
- Journal Title
  
  BMC Infect Dis.
  
  Volume: 19(1):598. Issue: 1 Pages: 598-598
- DOI
  10.1186/s12879-019-4236-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08642, KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-16K09537
[Journal Article] WT1 peptide-based immunotherapy for advanced thymic epithelial malignancies2018
- Author(s)
  Oji Y、Inoue M、Takeda Y、Hosen N、Shintani Y、Kawakami M、Harada T、Murakami Y、Iwai M、Fukuda M、Nishida S、Nakata J、Nakae Y、Takashima S、Shirakata T、Nakajima H、Hasegawa K、Kida H、Kijima T、Morimoto S、Fujiki F、Tsuboi A、Morii E、Morita S、Sakamoto J、Kumanogoh A、Oka Y、Okumura M、Sugiyama H
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 11 Pages: 2375-2382
- DOI
  10.1002/ijc.31253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-17K07215, KAKENHI-PROJECT-17K07216, KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-15K09476
[Journal Article] Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging2018
- Author(s)
  Jin Y, Takeda Y, Kondo Y, Tripathi LP, Kang S, Takeshita H, Kuhara H, Maeda Y, Higashiguchi M, Miyake K, Morimura O、Koba T、Hayama Y、Koyama S、Nakanishi K、Iwasaki T、Tetsumoto Si、Tsujino K、Kuroyama M、Iwahori K、Hirata H、Takimoto Ti、Suzuki M、Nagatomo I、Sugimoto K、Fujii Y、Kida H、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5145-5145
- DOI
  10.1038/s41598-018-23338-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K09580, KAKENHI-PROJECT-17K07268, KAKENHI-PROJECT-15K09219, KAKENHI-PROJECT-16K19451
[Journal Article] Rapid intracranial response to osimertinib, without radiotherapy, in nonsmall cell lung cancer patients harboring the EGFR T790M mutation: Two Case Reports2017
- Author(s)
  Koba T, Kijima T, Takimoto T, Hirata H, Naito Y, Hamaguchi M, Otsuka T, Kuroyama M, Nagatomo I, Takeda Y, Kida H, Kumanogoh A
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 96 Issue: 6 Pages: 6087-6087
- DOI
  10.1097/md.0000000000006087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461157, KAKENHI-PROJECT-15K09219, KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K09580, KAKENHI-PROJECT-16K19451
[Journal Article] Classification of idiopathic interstitial pneumonias using anti-myxovirus resistance-protein 1 autoantibody2017
- Author(s)
  Hamano Y, Kida H, Ihara S, Murakami A, Yanagawa M, Ueda K, Honda O, Tripathi LP, Arai T, Hirose M, Hamasaki T, Yano Y, Kimura T, Kato Y, Takamatsu H, Otsuka T, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Mori M, Nishikawa H, Mizuguchi K, Kijima T, Kitaichi T, Tomiyama N, Inoue Y, Kumanogoh A
- Journal Title
  
  Scientific Reports
  
  Volume: 23 Issue: 1 Pages: 43201-43201
- DOI
  10.1038/srep43201
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461157, KAKENHI-PROJECT-15K09203, KAKENHI-PROJECT-15K09219, KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K09580, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-17H06162
[Journal Article] Epiplakin is a paraneoplastic pemphigus autoantigen and related to bronchiolitis obliterans in Japanese patients.2016
- Author(s)
  (2)Tsuchisaka A, Numata S, Teye K, Natsuaki Y, Kawakami T, Takeda Y, Wang W, Ishikawa K, Goto M, Koga H, Sogame R, Ishii N, Takamori S, Hoshino T, Brandt O, Pas HH, Fujiwara S, Hashimoto T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database.2016
- Author(s)
  Higashiguchi M, Nagatomo I, Kijima T, Morimura O, Miyake K, Minami T, Koyama S, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A
- Journal Title
  
  FEBS Lett.
  
  Volume: 590 Pages: 4275-4286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09580
[Journal Article] COPDにおける慢性炎症2016
- Author(s)
  玄山宗到、平田陽彦、武田吉人
- Journal Title
  
  呼吸と循環
  
  Volume: 164 Pages: 137-143
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database2016
- Author(s)
  Higashiguchi M, Nagatomo I, Kijima T, Morimura O, Miyake K, Minami T, Koyama S, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A
- Journal Title
  
  FEBS letters
  
  Volume: 590 Issue: 23 Pages: 4275-4286
- DOI
  10.1002/1873-3468.12449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461157, KAKENHI-PROJECT-15K09219, KAKENHI-PROJECT-16K09537
[Journal Article] COPDにおける慢性炎症2016
- Author(s)
  玄山宗到、武田吉人
- Journal Title
  
  最新医学
  
  Volume: 71 Pages: 2326-2333
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] Transcriptomics Identify CD9 as a marker of murine IL-10-competent regulatory B cells.2015
- Author(s)
  (5)Sun J, Wang J, Pefanis E, Chao J, Rothschild G, Tachibana I, Chen JK, Ivanov II, Rabadan R, Takeda Y, Basu U.
- Journal Title
  
  Cell Rep.
  
  Volume: 10
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] Preventive Role of Tetraspanin CD9 in Systemic Inflammation of Chronic Obstructive Pulmonary Disease.2015
- Author(s)
  Takeda Y, Suzuki M, Jin Y, Tachibana I.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 53 Pages: 751-760
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] 呼吸器疾患における新規メッセンジャー：エクソソーム2015
- Author(s)
  武田吉人
- Journal Title
  
  分子呼吸器病
  
  Volume: 19 Pages: 13-16
- Data Source
  KAKENHI-PROJECT-15K09219
[Journal Article] 6.Development of microscopic polyangiitis-related pulmonary fibrosis in a patient with autoimmune pulmonary alveolar proteinosis.2014
- Author(s)
  Kinehara Y, Kida H, Inoue Y, Hirose M, Nakabayashi A, Takeuchi Y, Hayama Y, Fukushima K, Hirata H, Inoue K, Minami T, Nagatomo I, Takeda Y, Funakoshi T, Kijima T, Kumanogoh A.
- Journal Title
  
  BMC Pulm Med.
  
  Volume: 4 Pages: 172-172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] 7.A Retrospective Study of Prognostic Factors in Patients with Interstitial Pneumonia Receiving Long-Term Oxygen Therapy.2014
- Author(s)
  Higashiguchi M, Kijima T, Sumikawa H, Honda O, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Kida H, Tomiyama N, Kumanogoh A.
- Journal Title
  
  Lung
  
  Volume: 5 Pages: 210-214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] 8.Efficacy and Safety of Pirfenidone for Idiopathic Pulmonary Fibrosis.2014
- Author(s)
  Takeda Y, Tsujino K, Kijima T, Kumanogoh A
- Journal Title
  
  Patient Prefer Adherence.
  
  Volume: 21 Pages: 361-370
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Deletion of Tetraspanin CD9 Diminishes Lymphangiogenesis in Vivo and in Vitro.2013
- Author(s)
  (10) Iwasaki T, Takeda Y, Maruyama K, Yokosaki Y, Tsujino K, Tetsumoto S, Kuhara H, Nakanishi K, Otani Y, Jin Y, Kohmo S, Hirata H, Takahashi R, Suzuki M, Inoue K, Nagatomo I, Goya S, Kijima T, Kumagai T, Tachibana I, Kawase I, Kumanogoh A.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 2118-2131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Calretinin mediates apoptosis in small cell lung cancer cells expressing tetraspanin CD92013
- Author(s)
  (2) He P, Kuhara H, Tachibana I, Jin Y, Takeda Y, Tetsumoto S, Minami T, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Naka T, Morii E, Kawase I, Kumanogoh A
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 10 Pages: 225-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.2013
- Author(s)
  (9) Jin Y, Tachibana I, Takeda Y, He P, Kang S, Suzuki M, Kuhara H, Tetsumoto S, Tsujino K, Minami T, Iwasaki T, Nakanishi K, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Ito M, Saya H, Kumanogoh A.
- Journal Title
  
  PLoS One
  
  Volume: 9 Pages: 737-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Validation of non-invasive morphological and diffusion imaging in mouse emphysema by micro-CT and hyperpolarized ^129Xe MRI2013
- Author(s)
  Satoshi Tetsumoto, Yoshioto Takeda, Hirohiko Imai, et al.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 掲載決定 Issue: 4 Pages: 592-600
- DOI
  10.1165/rcmb.2012-0350oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163, KAKENHI-PROJECT-25461386
[Journal Article] Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.2013
- Author(s)
  (8) Minami T, Kijima T, Kohmo S, Arase H, Otani Y, Nagatomo I, Takahashi R, Miyake K, Higashiguchi M, Morimura O, Ihara S, Tsujino K, Hirata H, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Pages: 2669-2669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro. J Biol Chem.2013
- Author(s)
  Iwasaki T, Takeda Y, Maruyama K, Yokosaki Y, Tsujino K
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Pages: 2118-2131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Validation of noninvasive morphological and diffusion imaging in mouse emphysema by micro-computed tomography and hyperpolarized (129)Xe magnetic resonance imaging.2013
- Author(s)
  (11) Tetsumoto S, Takeda Y, Imai H, Kimura A, Jin Y, Nakanishi K, Maeda Y, Kuhara H, Tsujino K, Iwasaki T, Shigeta H, Kondo Y, Ito M, Minami T, Hirata H, Takahashi R, Kohmo S, Nagatomo I, Inoue K, Kida H, Kijima T, Tachibana I, Maeda N, Funahashi T, Shimomura I, Fujiwara H, Kumanogoh A.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 49 Pages: 592-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Early[ 18F] fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung2012
- Author(s)
  Takahashi R, Hirata H, Tachibana I, Shimosegawa E, Inoue A, Nagatomo I, Takeda Y, Kida H, Goya S, Kijima T, Yoshida M, Kumagai T, Kumanogoh A, Okumura M, Hatazawa J, Kawase I.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(1) Pages: 220-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] アディポネクチンとCOPD2012
- Author(s)
  中西香織，武田吉人
- Journal Title
  
  Angiology Frontier
  
  Volume: 11 Pages: 48-56
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] HER2 as therapeutic target for overcoming ATP-Binding cassette transporter-mediated chemoresistance in small cell lung cancer.2012
- Author(s)
  Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogho A
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11 Pages: 830-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] A Novel Link Between Adipocytes and COPD2012
- Author(s)
  Takeda Y, Nakanishi K, Tachibana I, Kumanogoh A
- Journal Title
  
  Vitam Horm
  
  Volume: 90 Pages: 419-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity2012
- Author(s)
  Kazuyuki Tsujino, Yoshito Takeda, Toru Arai, Yasushi Shintani, Ryosaku Inagaki, Hiroyuki Saiga, Takeo Iwasaki, Satoshi Tetsumoto, Yingji Jin, Shoichi Ihara, Toshiyuki Minami, Mayumi Suzuki, Izumi Nagatomo, Koji Inoue, Hiroshi Kida, Takashi Kijima, Mari Ito, Masanori Kitaichi, Yoshikazu Inoue, Isao Tachibana, Kiyoshi Takeda, Meinoshin Okumura, Martin E. Hemler, Atsushi Kumanogoh
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] 4-Hydroxy-2-nonenal induces chronic obstructive pulmonary disease-like histopathologic changes in mice2012
- Author(s)
  Takimoto T, Yoshida M, Hirata H, Kashiwa Y, Takeda Y, Goya S, Kijima T, Kumagai T, Tachibana I, Kawase I.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420(1) Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity.2012
- Author(s)
  Tsujino K, Takeda Y, Arai T, Shintani Y
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 186 Pages: 170-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] アディポネクチンとCOPD2012
- Author(s)
  武田吉人
- Journal Title
  
  分子呼吸器病
  
  Volume: 16 Pages: 16-20
- Data Source
  KAKENHI-PROJECT-24591129
[Journal Article] Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib2012
- Author(s)
  Tetsumoto S, Osa A, Kijima T, Minami T, Hirata H, Takahashi R, Kuhara H, Nagatomo I, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 17(2) Pages: 155-9
- NAID
  10030626570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] HER2 As Therapeutic Target for Overcoming ATP-Binding Cassette Transporter-Mediated Chemoresistance in Small Cell Lung Cancer2012
- Author(s)
  Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] CXCL12 as a biological marker for the diagnosis of tuberculous pleurisy2012
- Author(s)
  Kohmo S, Kijima T, Mori M, Minami T, Namba Y, Yano Y, Yoneda T, Takeda Y, Kitada S, Yamaguchi T, Tachibana I, Yokota S.
- Journal Title
  
  Tuberculosis(Edinb)
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Diminished metastasis in Tetraspanin CD151 Knockout mice2011
- Author(s)
  Yoshito Takeda, Qinglin Li, Alexander R. Kazarov, Mathieu Epardaud, Kutlu Elpek, Shannon J. Turley, Martin E. Hemler
- Journal Title
  
  Blood
  
  Volume: 118(2) Pages: 464-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice : implications for therapy2011
- Author(s)
  中西香織、武田吉人
- Journal Title
  
  Am J Respir Criti Care Med
  
  Volume: 183 Issue: 9 Pages: 1164-1175
- DOI
  10.1164/rccm.201007-1091oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992, KAKENHI-PROJECT-22590979
[Journal Article] Diminished metastasis in Tetraspanin CD151 Knockout mice2011
- Author(s)
  Takeda Y et al
- Journal Title
  
  Blood
  
  Volume: 118(2) Pages: 464-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer2011
- Author(s)
  Kijima T, Takeuchi K, Tetsumoto S, Shimada K, Takahashi R, Hirata H, Nagatomo I, Hoshino S, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1602-4
- NAID
  10030242650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Diminished metastasis in tetraspanin CD151-knockout mice2011
- Author(s)
  武田吉人
- Journal Title
  
  Blood
  
  Volume: 118 Issue: 2 Pages: 464-472
- DOI
  10.1182/blood-2010-08-302240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity : difference in metabolism as a possible mechanism2011
- Author(s)
  Takashi Kijima, Tomohito Shimizu, Shinpei Nonen, Mitsugi Furukawa, Yasushi Otani, Toshiyuki Minami, Ryo Takahashi, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida, Sho Goya, Yasushi Fujio, Junichi Azuma, Isao Tachibana, Ichiro Kawase
- Journal Title
  
  J Clin Oncol
  
  Volume: 29(19)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Involvement of Endothelial Apoptosis Underlying COPD-Like Phenotype in Adiponectin-Null Mice : Implications for Therapy2011
- Author(s)
  Nakanishi K, Takeda Y(equally first author), Tetsumoto S, Iwasaki T, Tsujino K, Kuhara H, Jin Y, Nagatomo I, Kida H, Goya S, Kijima T, Maeda N, Funahashi T, Shimomura I, Tachibana I, Kawase I.
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 183(9) Pages: 1164-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Cell surface tetraspanin CD9 mediates chemoresistance in small cell lung cancer2010
- Author(s)
  Kohmo S, Kijima T, Otani Y, Mori M, Minami T, Takahashi R, Nagatomo I, Takeda Y, Kida H, Goya S, Yoshida M, Kumagai T, Tachibana I, Yokota S, Kawase I.
- Journal Title
  
  Cancer Res
  
  Volume: 70(20) Pages: 8025-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] COPDにおけるテトラスパニンの役割.2010
- Author(s)
  武田吉人、鈴木真優美、立花功
- Journal Title
  
  The Lung perspective 18
  
  Pages: 291-298
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] COPDにおけるテトラスパニンの役割2010
- Author(s)
  武田吉人、鈴木真優美、立花功
- Journal Title
  
  The Lung perspective
  
  Volume: 18 Pages: 291-298
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] A clear correlation between WT1-specific Th response and clinical response in WT1 CTL epitope vaccination2010
- Author(s)
  Fujiki F., Oka Y., Kawakatsu M., Tsuboi A., Harada Y., Hosen N., Nishida S., Shirakata T., Nakajima H., Tatsumi N., Hashimoto N., Taguchi T., Ueda S., Nonomura N., Takeda Y., Ito T., Myoui A., Izumoto Izumoto S., Maruno M., Yoshimine T., Noguchi S., Okuyama A., Kawase I., Oji Y., Sugiyama H
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 2247-2254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] マクロファージの活性化におけるCD9(tetraspanin)の役割.2010
- Author(s)
  立花功、鈴木真優美、武田吉人, 他
- Journal Title
  
  臨床免疫・アレルギー科 53
  
  Pages: 214-220
- NAID
  40017012899
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] COPDにおけるテトラスパニンの役割2010
- Author(s)
  武田吉人、鈴木真優美、立花功
- Journal Title
  
  The Lung perspective
  
  Volume: 18 Pages: 291-298
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] マクロファージの活性化におけるCD9(tetraspanin)の役割2010
- Author(s)
  立花功、鈴木真優美、武田吉人, 他
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 53 Pages: 214-220
- NAID
  40017012899
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients : an important role of bone marrow as a secondary lymhpoid organ2010
- Author(s)
  Murao A., Oka Y., Tsuboi A., Elisseeva O. A., Harada Y., Fujiki F., Nakajima H., Nishida S., Hosen N., Shirakata T., Hashimoto N., Myoui A., Ueda T., Takeda Y., Osaki T., Enomoto T., Yoshikawa H., Kimura T., Oji Y., Kawase I., Sugiyama H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 848-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人, 立花功, 川瀬一郎
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation2009
- Author(s)
  Suzuki M, Tachibana I, Takeda Y et al
- Journal Title
  
  J Immunol
  
  Volume: 182 Pages: 6485-6493
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation2009
- Author(s)
  Mayumi Suzuki, Isao Tachibana, Yoshito Takeda, Ping He, Seigo Minami, Takeo Iwasaki, Sho Goya, Takashi Kijima, Toru Kumagai, Mitsuhiro Yoshida, Tadashi Osaki, and Ichiro Kawase
- Journal Title
  
  J Immunol
  
  Volume: 182(10) Pages: 6485-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation.2009
- Author(s)
  鈴木真優美, 立花功, 武田吉人, et. al.
- Journal Title
  
  J Immunol 182
  
  Pages: 6485-6493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析.2009
- Author(s)
  武田吉人
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] COPDモデルとしてのテトラスパニンCD9/ CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人
- Journal Title
  
  International Review of Asthma & COPD
  
  Volume: 11 Pages: 31-36
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-20590897
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人, 立花功, 川瀬一郎
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation2009
- Author(s)
  Suzuki M, Tachibana I, Takeda Y
- Journal Title
  
  J Immunol. 15
  
  Pages: 6485-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation2009
- Author(s)
  Suzuki M, Tachibana I, Takeda Y
- Journal Title
  
  J Immunol. 15
  
  Pages: 6485-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] Doubot i 1hrone deficiencyot tetraspanins CD9 and CD81 alters cell mty and protease prouduction of macrophages and causes Ccobst ruetive pulmonary disease-like pheno type in mice2008
- Author(s)
  Takeda Y, He P, Tach ibana l, et al
- Journal Title
  
  J Biol Chem 283
  
  Pages: 26089-26097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590897
[Patent] 特許願2018
- Inventor(s)
  滝本　宜之、武田　吉人、熊ノ郷　淳、井上　義一
- Industrial Property Rights Holder
  滝本　宜之、武田　吉人、熊ノ郷　淳、井上　義一
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] Identification of novel biomarkers for malignant pleural mesothelioma by proteomics of serum exosomes2021
- Author(s)
  Yuko Abe, Yoshito Takeda, Hanako Yoshimura, Taro Koba, Yasuhiko Suga, Kiyoharu Fukushima, Takayuki Shiroyama, Syohei Koyama, Haruhiko Hirata, Kota Iwahori, Izumi Nagatomo, Atsushi Kumanogoh
- Organizer
  第80回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] Leucine-Rich a2-Glycoprotein as a Potential Biomarker for multicentric Castleman disease with pulmonary involvement2021
- Author(s)
  So Takata1、Yoshito Takeda1、Haruhiko Hirata1、Takayoshi Morita1、Yu Futami1、Yujiro Naito1、Kentaro Masuhiro1、Mana Nakayama1、Tetsuji Naka2、Atsushi Kumanogoh1.
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] Discovery of novel biomarkers of small cell lung cancer by proteomics of exosomes2021
- Author(s)
  Hanako Yoshimura, Yoshito Takeda, Taro Koba, Yasuhiko Suga, Kiyoharu Fukushima, Takayuki Shiroyama, Haruhiko Hirata, Shohei Koyama, Izumi Nagatomo, Kota Iwahori, Mari Itoh, Atsushi Kumanogoh
- Organizer
  ATS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 次世代プロテオミクスによる進行性線維化を伴う間質性肺疾患の新規バイオマーカー探索2021
- Author(s)
  榎本貴俊, 武田吉人, 足立雄一, 網屋沙織, 野田成美, 白井雄也, 福島清春, 白山敬之, 三宅浩太郎, 平田陽彦, 足立淳, 夏目やよい, 伊藤眞里, 熊ノ郷淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 気管支肺胞洗浄液を用いた肺癌微小環境の免疫解析によるニボルマブ効果予測因子の探索2021
- Author(s)
  内藤　祐二朗、田宮　基裕、益弘　健太朗、小山　正平、白山　敬之、井上　貴子、西野　和美、鈴木　秀和、岡本　紀雄、平島　智徳、熊谷　融、武田　吉人、熊ノ郷　淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 「PRISM」データから見えてきた新たな線維化バイオマーカー2021
- Author(s)
  白井雄也、武田吉人、足立雄一、榎本貴俊、網屋沙織、野田成美、福島清春、白山敬之、三宅浩太郎、平田陽彦、足立淳、夏目やよい、伊藤眞里、熊ノ郷淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 次世代プロテオミクスによる進行性線維化を伴う間質性肺疾患の新規バイオマーカー探索2021
- Author(s)
  榎本貴俊, 武田吉人, 白井雄也, 足立淳, 伊藤眞里, 夏目やよい, 熊ノ郷淳
- Organizer
  第8回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 次世代プロテオミクスとバイオインフォマティクスが紐解くIPFとNSIPの病態解明2021
- Author(s)
  足立雄一　武田吉人　榎本貴俊　網屋沙織　野田成美　原伶奈　新津敬之　白井雄也　福島清春　白山敬之　三宅浩太郎　平田晴彦　夏目やよい足立淳伊藤眞里熊ノ郷淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] エクソソームの次世代プロテオミクスによるサルコイドーシスの新規バイオマーカー探索2021
- Author(s)
  網屋沙織，武田吉人，足立雄一，榎本貴俊，新津敬之，野田成美，原　伶奈，白井雄也，白山敬之，三宅浩太郎，平田陽彦，足立　淳，伊藤眞里，夏目やよい，熊ノ郷淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] エクソソームの次世代プロテオミクスによる悪性胸膜中皮腫の新規バイオマーカー開発2021
- Author(s)
  安部祐子, 武田吉人, 木庭太郎, 福島清春, 白山敬之,平田陽彦, 足立淳, 伊藤眞里, 横井　崇, 南　俊行, 栗林　康造, 木島　貴志, 熊ノ郷淳
- Organizer
  第61回呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 血清エクソソームの最新プロテオミクスによる新規喘息・COPDバイオマーカーの探索2019
- Author(s)
  木庭太郎、武田吉人、玄山宗到、木田博、熊ノ郷淳
- Organizer
  日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] Proteomic Profiling of Serum Exosomes to Identify Novel Biomarkers for COPD2019
- Author(s)
  T. Koba, Y. Takeda, R. Narumi
- Organizer
  アメリカ胸部学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] Proteomic profiling of serum exosomes to identify novel biomarkers for lymphangioleiomyomatosis2019
- Author(s)
  Takayuki Takimoto1, Yoshito Takeda1, Takashi Shiromizu2
- Organizer
  アメリカ胸部学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 血清エクソソームの最新プロテオミクスによる新規COPDバイオマーカーの同定2019
- Author(s)
  木庭太郎、武田吉人、玄山宗到、木田博、熊ノ郷淳
- Organizer
  日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] Proteomic profiling of serum exosomes to find novel biomarkers in sarcoidosis2019
- Author(s)
  Yu Nishijima-Futami 1Yoshito Takeda, 2Ryohei Narumi
- Organizer
  アメリカ胸部学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 分子オーガナイザー：テトラスパニン　～肺の恒常性維持から老化まで～2019
- Author(s)
  武田吉人
- Organizer
  日本細胞生物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08650
[Presentation] 血清エクソソームのプロテオミクスによるリンパ脈管筋腫症のバイオマーカー探索2018
- Author(s)
  滝本宜之，武田　吉人，鳴海　良平, 白水　崇，木庭　太郎, 玄山　宗到，平田　陽彦, 広瀬　雅樹, 木田　博，南　正人,　伊藤　眞理, 井上　義一, 朝長　毅, 熊ノ郷　淳
- Organizer
  第3回　LAM研究会
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] Discovery of novel COPD biomarker from peripheral exosomes by Quantitative proteomics2018
- Author(s)
  武田吉人、木庭太郎、葉山善友、玄山宗到、滝本宜之、木田博、熊ノ郷淳、白水崇、朝長毅
- Organizer
  米国胸部疾患学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] Identification of novel biomarkers for lymphangioleiomyomatosis by proteomics from serum exosomes.2018
- Author(s)
  Takayuki Takimoto, Yoshito Takeda, Takashi Shiromizu, Ryohei Narumi, Taro Koba, Takanori Matsuki, Muneyoshi Kuroyama, Hiroshi Kida, Masaki Hirose, Yoshikazu Inoue, Takeshi Tomonaga, Atsushi Kumanogoh
- Organizer
  ATS 2018 米国胸部疾患学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] 肺リンパ脈管筋腫症におけるエクソソームの最新プロテオーム解析2018
- Author(s)
  滝本　宜之，武田　吉人，木庭太郎, 玄山　宗到，木田　博, 広瀬　雅樹, 井上　義一, 鳴海　良平, 朝長　毅, 熊ノ郷　淳,
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] 最新プロテオミクスによる肺リンパ脈管筋腫症の新規バイオマーカーの探索2017
- Author(s)
  滝本　宜之，武田　吉人，白水崇、平田　陽彦，玄山　宗到，木田　博，木島　貴志，朝長　毅、熊ノ郷　淳
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] Discovery of novel COPD biomarker from peripheral exosomes by Quantitative proteomics2017
- Author(s)
  武田吉人、木庭太郎、葉山善友、玄山宗到、滝本宜之、木田博、熊ノ郷淳、白水崇、朝長毅
- Organizer
  呼吸器学会総会
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 当院におけるリンパ脈管筋腫症（LAM）に対する薬物治療の検討2017
- Author(s)
  滝本宜之，平田陽彦，木庭太郎, 玄山宗到，大塚倫之、長友泉, 武田吉人，木田博，木島貴志，熊ノ郷淳
- Organizer
  第40回日本呼吸器内視鏡学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] 血清エクソソームのプロテオミクスによる肺リンパ脈管筋腫症の病態解明2017
- Author(s)
  滝本　宜之, 武田　吉人，白水　崇，木庭　太郎, 玄山　宗到，平田　陽彦, 広瀬　雅樹, 木田　博，南　正人, 伊藤　眞理, 井上　義一, 朝長　毅, 熊ノ郷　淳
- Organizer
  第2回　LAM研究会
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] エクソソームの最新プロテオミクスによる喘息の新規バイオマーカー探索2017
- Author(s)
  武田吉人1・玄山宗到1・木庭太郎1・滝本宣之1・木田博1・植田幸嗣2・熊ノ郷淳1
- Organizer
  プロテオーム学会総会
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 分子オーガナイザー：テトラスパニン～肺の恒常性維持から老化まで～2016
- Author(s)
  武田吉人
- Organizer
  第39回　日本分子生物学会総会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 当院におけるLAM診療の現状と展望2016
- Author(s)
  滝本宜之，平田陽彦，玄山宗到，武田吉人，木田博，木島貴志，熊ノ郷淳
- Organizer
  第1回　LAM研究会
- Place of Presentation
  CIVI研修センター（東京都・千代田区）
- Year and Date
  2016-10-09
- Data Source
  KAKENHI-PROJECT-16K09581
[Presentation] Tetraspanins: Markers for exosomes? or Molecular organizers?2016
- Author(s)
  武田吉人
- Organizer
  第3回日本細胞外小胞学会
- Place of Presentation
  広島
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] エクソソームの最新プロテオミクスによる新規COPDバイオマーカーの探索2016
- Author(s)
  武田吉人、玄山宗到、葉山善友、金英姫、木島貴志、熊ノ郷　淳
- Organizer
  第56回　日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] Proteomic profiling of peripheral exosomes leads to the identification of novel biomarker candidates for emphysema.2016
- Author(s)
  武田吉人、葉山善友、平田陽彦、木島貴志、朝長　毅、熊ノ郷　淳
- Organizer
  2016 　米国胸部疾患学会
- Place of Presentation
  サンフランシスコ（米国）
- Year and Date
  2016-04-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 分子オーガナイザー：テトラスパニン～肺の恒常性維持から老化まで～2016
- Author(s)
  武田吉人
- Organizer
  第56回　日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 炎症性呼吸器疾患の病態解明と新規治療法開発を目指したマウスモデル作成2015
- Author(s)
  武田吉人
- Organizer
  第５５回　日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] 様々な老化表現型を示す新規老化モデルマウスの開発と病態解明2015
- Author(s)
  武田吉人
- Organizer
  第１５回　日本抗加齢医学会総会　　第５回抗加齢奨励賞受賞者講演
- Place of Presentation
  福岡
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] CD9/CD81 double knock out mice as a novel mouse model for accelerated senescence.2015
- Author(s)
  武田吉人，金英姫，杉本研，近藤康，伊藤眞里，藤井雄太，水口賢治，Lokesh P. Tripathi，熊ノ郷淳
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] エクソソームのプロテオミクスによる慢性炎症マーカーの探索2015
- Author(s)
  武田吉人，金英姫，葉山善友，木島貴志，熊ノ郷淳，久米秀明，朝長毅
- Organizer
  第５５回　日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09219
[Presentation] Tetraspanins CD9 and CD81 Double-Knockout mice spontaneously develop not only COPD-like phenotype, but also multiple aging phenotypes.2014
- Author(s)
  武田吉人，近藤　康、金英姫，立花功，木島貴志，熊ノ郷淳
- Organizer
  American Thoracic Society International Conference 2014
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2014-05-21
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] Double deletion of tetraspanins CD9 and CD81 in mice causes not only COPD-like phenotypte, but also a syndrome resembling aging2014
- Author(s)
  武田吉人、金　英姫，長友泉
- Organizer
  第５４回　日本呼吸器学会学術講演会
- Place of Presentation
  大阪
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] COPDにおけるエクソソーム:慢性炎症の視点から2014
- Author(s)
  武田吉人
- Organizer
  第５４回　日本呼吸器学会学術講演会
- Place of Presentation
  大阪
- Year and Date
  2014-04-27
- Invited
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 肺の生活習慣病：COPDにおける慢性炎症2014
- Author(s)
  武田吉人
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 超偏極 129 Xe MRIによる新たなマウス気腫評価法の確立2013
- Author(s)
  鉄本訓史，武田吉人，金英姫，中西香織，前田陽平，井上幸治，長友泉，木田博，
- Organizer
  第５３回　日本呼吸器学会学術講演会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 超偏極129XeMRIによる新たなマウス肺気腫評価法確立2013
- Author(s)
  鉄本訓史　武田吉人　金、中西、前田　井上幸治　長友泉　木田博　木島貴志　立花功　熊ノ郷　淳
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] Validation of non-invasive morphological and diffusion imaging in mouse emphysema by micro-CT and hyperpolarized 129Xe MRI2013
- Author(s)
  Satoshi Tetsumoto, Yoshito Takeda
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  フィラデルフィア
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] Double deletion of tetraspanins CD9 and CD81 in mice spontaneously develops not only COPD-like phenotype, but also multiple aging phenotypes.2013
- Author(s)
  武田吉人，金英姫，辻野和之，立花功，熊ノ郷淳
- Organizer
  American Thoracic Society International Conference 2013
- Place of Presentation
  フィラデルフィア（アメリカ）
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 新たな老化モデルとしてのテトラスパニンCD9/CD81二重欠損マウス2013
- Author(s)
  武田吉人，金英姫，立花功，杉本研，楽木宏実，熊ノ郷淳
- Organizer
  第５５回日本老年医学会学術集会総会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 新たな老化モデルとしてのテトラスパニンCD9/CD81二重欠損マウス2013
- Author(s)
  武田吉人，近藤康，金英姫，立花功，杉本研，楽木宏実，熊ノ郷淳
- Organizer
  第３６回日本分子生物学会総会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 肺胞上皮細胞のintegrityを担うテトラスパニンCD1512013
- Author(s)
  武田吉人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] テトラスパニンCD9/CD81はSIRT 1の制御によりアンチエイジング作用を示す2013
- Author(s)
  武田吉人，金英姫，井上幸治，木田博，木島貴志，伊藤真里，立花功，熊ノ郷淳
- Organizer
  第５３回　日本呼吸器学会学術講演会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] 肺胞上皮細胞のintegrityを担うテトラスパニンCD1512013
- Author(s)
  武田吉人
- Organizer
  第５３回　日本呼吸器学会学術講演会シンポジウム
- Place of Presentation
  東京都
- Invited
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] CD151は肺胞上皮の安定化を介して肺の線維化を制御する2012
- Author(s)
  辻野和之、武田吉人、金英姫、鉄本訓史、鈴木真優美、木田博、木島貴志、立花功、熊ノ郷淳
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  神戸
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-21590992
[Presentation] Double deletion of CD9 and CD81 in mice leads to a syndrome resembling aging．2012
- Author(s)
  Takeda Y, Jin Y, Tachibana I, Kumanogoh A．
- Organizer
  Keystone Symposia
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] Deletion of tetraspanin CD151 in mice spontaneously leads to pulmonary fibrosis with age through epithelial disintegrity2012
- Author(s)
  Yoshito Takeda, Kazuyuki Tsujino, Isao Tachibana, Atsushi Kumanogoh
- Organizer
  アメリカ胸部疾患学会
- Place of Presentation
  サンフランシスコ米国
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-21590992
[Presentation] Deletion of tetraspanin CD151 in mice spontaneously leads to pulmonary fibrosis with age through epithelial disintegrity．2012
- Author(s)
  Takeda Y, Tsujino K, Tachibana I, Kumanogoh A．
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] テトラスパニンCD9/CD81二重欠損マウスはCOPDモデル？それとも老化モデル？2012
- Author(s)
  武田吉人，金英姫，立花　功，熊ノ郷　淳．
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591129
[Presentation] Tetraspanin CD9 link VEGFR-3 and integrins in physiological and pathological lymphangiogenesis2011
- Author(s)
  武田吉人
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] CD151 KO mice spontaneously develop lung fibrosis, hepatic fibrosis and skin fibrosis via augmented TGF-β signaling2011
- Author(s)
  武田吉人
- Organizer
  FASEB Meeting
- Place of Presentation
  Vermont (USA)(招待講演)
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-21590992
[Presentation] Tetraspanin CD9 functions as" linkers" of VEGFR-3 signaling in the regulation of physiological and pathological lymphangiogenesis2011
- Author(s)
  武田吉人
- Organizer
  FASEB Summer Research Conference
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] CD151 KO mice spontaneously develop lung fibrosis, hepatic fibrosis and skin fibrosis via augmented TGF-signaling2011
- Author(s)
  Yoshito Takeda, Kazuyuki Tsujino, Isao Tachibana, Atsushi Kumanogoh
- Organizer
  FASEB Meeting
- Place of Presentation
  Vermont(USA)
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-21590992
[Presentation] Tetraspanin CD9 functions as" linkers" of VEGFR-3 signaling in the regulation of physiological and pathological lymphangiogenesis2010
- Author(s)
  武田吉人
- Organizer
  第4回Tetraspanins Meeting
- Place of Presentation
  London
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] Tetraspanin CD9 link VEGFR-3 and integrins in physiological and pathological lymphangiogenesis2010
- Author(s)
  武田吉人
- Organizer
  日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] リンパ管新生におけるCD9の役割2010
- Author(s)
  武田吉人
- Organizer
  第4回ヨーロッパテトラスパニンミーティング
- Place of Presentation
  バーミンガム大学(イギリス)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] COPD患者の末梢血単球における tetraspanin の発現解析2009
- Author(s)
  周博, 武田吉人
- Organizer
  第49回日本呼吸器学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-21
- Data Source
  KAKENHI-PROJECT-20590922
[Presentation] COPD患者の末梢血単球における tetraspanin の発現解析2009
- Author(s)
  周博, 武田吉人
- Organizer
  第49回日本呼吸器学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-21
- Data Source
  KAKENHI-PROJECT-21590992
[Presentation] 大腸癌、膵癌に対するWT1ペプチドワクチン療法2008
- Author(s)
  岡芳弘、西田純幸、武田裕、尾路祐介ら(岡芳弘 : 10人中1番目、尾路祐介 : 10人中5番目)
- Organizer
  第21回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  東京
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19590894

1. OKA Yoshihiro (20273691)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. TACHIBANA Isao (60324761)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
3. 井上義一 (90240895)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
4. TAKAHASHI Ryo (10546865)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. Takimoto Takayuki (60767854)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
6. OTSUKA Tomoyuki (20730576)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HIRATA HARUHIKO (30546867)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 川瀬一郎 (10161324)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. OJI YUSUKE (20294100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. OSAKI TADASHI (50324778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGATOMO Izumi (10570583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kimura Atsuomi (70303972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUJIWARA Hideaki (90107102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IMAI Hirohiko (40506466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 植田幸嗣 (10509110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 北島一宏 (80448860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山門亨一郎 (20263022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 甲斐田勇人 (40299425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大崎洋充 (90392349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渡部直史 (90648932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 木島貴志 (90372614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 南俊行 (00705113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 高濱隆幸 (90716359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 清水重喜 (30336672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 二見真史 (50975191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KATO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. KIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
28. KUMANOGOH Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
29. MOTOOKA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 田中良哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 岡田随象

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 熊郷淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 福島清春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEDA YOSHITO 武田 吉人

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個別化医療を目指した進行性肺線維症の病態解明と新規治療法開発Principal Investigator

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次世代プロテオミクスが紐解く個別化医療に有用なPF-ILDの新規BM開発Principal Investigator

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Discovery of novel BM and pathogenesis in COPD by trans-omicsPrincipal Investigator

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Proteomics of peripheral exosome identifies novel biomarkers for COPDPrincipal Investigator

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Role of adiponectin in COPDPrincipal Investigator

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TAKEDA YOSHITO 武田吉人