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AKASHI MASAYA  明石 昌也

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AKASHI Masaya  明石 昌也

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Researcher Number 40597168
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 神戸大学, 医学研究科, 教授
2017 – 2018: 神戸大学, 医学研究科, 講師
2013 – 2017: 神戸大学, 医学部附属病院, 助教
2011 – 2012: 神戸大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Medium-sized Section 90:Biomedical engineering and related fields
Keywords
Principal Investigator
リンパ管 / 口腔癌 / 顎骨壊死 / 口腔感染症 / リンパ管新生 / 血管新生 / 歯性感染症 / 骨髄炎 / 細胞接着 / リンパ節 … More / 悪性腫瘍 / リンパ節転移 / 放射線治療 / 内皮細胞 / 細胞間接着 / 癌 / 国際情報交換 / 炎症性サイトカイン / 細胞間接着複合体 / リンパ管内皮細胞 … More
Except Principal Investigator
口腔がん / 口腔癌 / 炭酸ガス / 咀嚼機能評価 / メタボローム解析 / 自己免疫疾患モデ ル / 好中球 / 自己免疫疾患モデル / ESSDAI / シェーグレン症候群 / インスリン抵抗性 / ミトコンドリア機能不全 / 筋肉量減少 / がん悪液質 / 癌関連線維芽細胞 / 酸化チタニウム / 頭頚部がん / ルチン修飾 / 植物成分 / 放射線照射 / 酸化チタン / ポリフェノール修飾 / 過酸化水素 / 二酸化チタンナノ粒子 / 扁平上皮癌 / GC/MS / オミックス / メタボローム / 口腔リハビリテーション / グミゼリー / 付着性 / 粘着力 / 顎骨切除 / 咀嚼指数 / オーラルフレイル / 総義歯咀嚼能率判定表 / 咀嚼機能 / 凝集性 / 硬さ / テクスチャーアナライザー / 副作用 / 放射線抵抗性 / 低酸素環境 / 放射線治療 / 治療抵抗性 / 放射線 / 口腔顎顔面再建外科学 / 歯学 / 咀嚼筋 / 口腔癌再建患者 / 筋機能MRI / 顎骨切除後再建 / 筋機能MRI / ARONJ / LED / 顎骨壊死 / 低出力レーザー治療 Less
  • Research Projects

    (13 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (23 People)
  •  がん悪液質を想定した筋肉量減少に対するミトコンドリア機能改善を介した新規治療法

    • Principal Investigator
      武田 大介
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  顎骨壊死に対する腐骨分離促進療法の探索Principal Investigator

    • Principal Investigator
      明石 昌也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  好中球に着眼したシェーグレン症候群の新規病理分類提案と治療薬探索

    • Principal Investigator
      後藤 育子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  ミトコンドリアの正常化と癌関連線維芽細胞の再教育を目指した新規口腔癌治療法の開発

    • Principal Investigator
      長谷川 巧実
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  統合オミックス解析による口腔がん制御機構の解明と創薬標的の網羅的探索

    • Principal Investigator
      木本 明
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  Development of treatment system for periodontal disease and oral cancer using bio-compatible titanium dioxide

    • Principal Investigator
      OGINO CHIAKI
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Kobe University
  •  Development of a new evaluation method for chewing function applying basic food science and its ripple effect on oral flail

    • Principal Investigator
      渋谷 恭之
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nagoya City University
  •  Elucidation of the mechanisms of transition from odontogenic infection to osteomyelitis of the jaw focusing on angiogenesis and lymphangiogenesisPrincipal Investigator

    • Principal Investigator
      Akashi Masaya
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  Development of cancer therapies to improve resistance and reduce side effects

    • Principal Investigator
      Hasegawa Takumi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  Low-level laser therapy: A novel therapy for ARONJ with metabolomic analysis

    • Principal Investigator
      Hiroaki Suzuki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kobe University
  •  Myofunction MRI analysis of the oral cancer reconstruction case

    • Principal Investigator
      FURUDOI SHUNGO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kobe University
  •  Analysis of characteristics of lymphatic microcirculation within metastatic lymph nodes focusing on endothelial cell junctional complexPrincipal Investigator

    • Principal Investigator
      Akashi Masaya
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kobe University
  •  Characterization of junctional complex of lymphatic endothelial cells in caner lymphangiogenesisPrincipal Investigator

    • Principal Investigator
      AKASHI Masaya
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kobe University

All 2023 2022 2021 2020 2019 2018 2014 2012 2011

All Journal Article Presentation

  • [Journal Article] Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model2023

    • Author(s)
      Tadokoro Yoshiaki、Takeda Daisuke、Murakami Aki、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
    • Journal Title

      PLOS ONE

      Volume: 18 Issue: 8 Pages: e0290357-e0290357

    • DOI

      10.1371/journal.pone.0290357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10193
  • [Journal Article] Relationship of Mitochondrial-Related Protein Expression with the Differentiation, Metastasis, and Poor Prognosis of Oral Squamous Cell Carcinoma2023

    • Author(s)
      Murakami Aki、Takeda Daisuke、Hirota Junya、Saito Izumi、Amano-Iga Rika、Yatagai Nanae、Arimoto Satomi、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
    • Journal Title

      Cancers

      Volume: 15 Issue: 16 Pages: 4071-4071

    • DOI

      10.3390/cancers15164071

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10193
  • [Journal Article] The Efficacy of Carbon Dioxide Paste in Alleviating Pain in Patients After Neck Dissection: Protocol for a Double-Blinded, Randomized Controlled Trial2023

    • Author(s)
      Tadokoro Yoshiaki、Takeda Daisuke、Saito Izumi、Yatagai Nanae、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
    • Journal Title

      JMIR Research Protocols

      Volume: 12 Pages: e50500-e50500

    • DOI

      10.2196/50500

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-22K10193
  • [Journal Article] Exploratory clinical trial to evaluate the efficacy and safety of carbon dioxide paste in healthy people2022

    • Author(s)
      Yatagai Nanae、Hasegawa Takumi、Kyotani Katsusuke、Noda Tomohiro、Amano Rika、Saito Izumi、Arimoto Satomi、Takeda Daisuke、Kakei Yasumasa、Akashi Masaya
    • Journal Title

      Medicine

      Volume: 101 Issue: 29 Pages: e29511-e29511

    • DOI

      10.1097/md.0000000000029511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K10193, KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-19K19156
  • [Journal Article] Local application of a transcutaneous carbon dioxide paste prevents excessive scarring and promotes muscle regeneration in a bupivacaine‐induced rat model of muscle injury2022

    • Author(s)
      Hirota Junya、Hasegawa Takumi、Inui Atsuyuki、Takeda Daisuke、Amano‐Iga Rika、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Akashi Masaya
    • Journal Title

      International Wound Journal

      Volume: 20 Issue: 4 Pages: 1151-1159

    • DOI

      10.1111/iwj.13974

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10193, KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-19K19156
  • [Journal Article] Bacterial Colonization of the Condyle in Patients with Advanced Mandibular Osteoradionecrosis: Analysis of Hemimandibulectomy Specimens2021

    • Author(s)
      Takeda Daisuke、Hashikawa Kazunobu、Shigeoka Manabu、Kanzawa Maki、Yatagai Nanae、Arimoto Satomi、Kusumoto Junya、Hasegawa Takumi、Terashi Hiroto、Akashi Masaya
    • Journal Title

      International Journal of Dentistry

      Volume: 2021 Pages: 1-8

    • DOI

      10.1155/2021/9998397

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10331
  • [Journal Article] Local Application of Transcutaneous Carbon Dioxide Paste Decreases Inflammation and Accelerates Wound Healing2021

    • Author(s)
      Amano-Iga Rika、Hasegawa Takumi、Takeda Daisuke、Murakami Aki、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Kakei Yasumasa、Sakakibara Akiko、Akashi Masaya
    • Journal Title

      Cureus

      Volume: 13

    • DOI

      10.7759/cureus.19518

    • NAID

      120007179182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09788, KAKENHI-PROJECT-19K19156
  • [Journal Article] Transcutaneous Carbon Dioxide Decreases Immunosuppressive Factors in Squamous Cell Carcinoma In Vivo2021

    • Author(s)
      Yatagai Nanae、Hasegawa Takumi、Amano Rika、Saito Izumi、Arimoto Satomi、Takeda Daisuke、Kakei Yasumasa、Akashi Masaya
    • Journal Title

      BioMed Research International

      Volume: 5568428 Issue: 1 Pages: 1-9

    • DOI

      10.1155/2021/5568428

    • NAID

      120007125723

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09788, KAKENHI-PROJECT-19K19156
  • [Journal Article] JCAD expression and localization in human blood endothelial cells.2020

    • Author(s)
      Shigeoka M, Arimoto S, Akashi M.
    • Journal Title

      Heliyon.

      Volume: 6 Issue: 10 Pages: e05121-e05121

    • DOI

      10.1016/j.heliyon.2020.e05121

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10331, KAKENHI-PROJECT-19K19157
  • [Journal Article] Ionizing radiation enhances paracellular permeability through alteration of intercellular junctions in cultured human lymphatic endothelial cells2018

    • Author(s)
      Megumi Kishimoto, Masaya Akashi, Yasumasa Kakei, Junya Kusumoto, Akiko Sakakibara, Takumi Hasegawa, Shungo Furudoi, Ryohei Sasaki, Takahide Komori
    • Journal Title

      Lymphatic Research and Biology

      Volume: 印刷中 Issue: 4 Pages: 390-396

    • DOI

      10.1089/lrb.2017.0072

    • NAID

      120006543332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20522, KAKENHI-PROJECT-18K07752, KAKENHI-PROJECT-16K15581, KAKENHI-PROJECT-17K16442
  • [Journal Article] Four-Dimensional Computed Tomography Evaluation of Condylar Movement in a Patient With Temporomandibular Joint Osteoarthritis2018

    • Author(s)
      Akashi Masaya、Hasegawa Takumi、Takahashi Satoru、Komori Takahide
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 76 Issue: 2 Pages: 304-313

    • DOI

      10.1016/j.joms.2017.10.012

    • NAID

      120006541952

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11907, KAKENHI-PROJECT-16K10278
  • [Journal Article] Computed Tomographic Evaluation of Posttreatment Soft-Tissue Changes by Using a Lymphedema Scoring System in Patients with Oral Cancer2018

    • Author(s)
      Akashi Masaya、Teraoka Shun、Kakei Yasumasa、Kusumoto Junya、Hasegawa Takumi、Minamikawa Tsutomu、Hashikawa Kazunobu、Komori Takahide
    • Journal Title

      Lymphatic Research and Biology

      Volume: 16 Issue: 2 Pages: 147-153

    • DOI

      10.1089/lrb.2016.0063

    • NAID

      120006543331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11907
  • [Journal Article] 薬剤関連顎骨壊死の転帰に影響する因子についての検討2018

    • Author(s)
      古土井春吾,岩田英治,岸本恵美,高橋淳子,楠元順哉,明石昌也,古森孝英
    • Journal Title

      日本口腔感染症学会雑誌

      Volume: 25 Pages: 71-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11907
  • [Journal Article] Alteration of cell-cell junctions in cultured human lymphatic endothelial cells with inflammatory cytokine stimulation.2014

    • Author(s)
      Kakei Y, Akashi M, Shigeta T, Hasegawa T, Komori T.
    • Journal Title

      Lymphatic Research and Biology

      Volume: 12 Issue: 3 Pages: 136-143

    • DOI

      10.1089/lrb.2013.0035

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23792340
  • [Journal Article] p16 overexpression in malignant and premalignant lesions of the oral and esophageal mucosa following allogeneic hematopoietic stem cell transplantation2012

    • Author(s)
      Yasumasa Kakei, Masaya Akashi, Hideki Komatsubara, Tsutomu Minamikawa, Takahide Komori
    • Journal Title

      Head & Neck Oncology

      Volume: 4 Issue: 1 Pages: 1-4

    • DOI

      10.1186/1758-3284-4-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792340
  • [Journal Article] Phosphorylation state regulates the localization of Scribble at2011

    • Author(s)
      Ken Yoshihara, Junichi Ikenouchi, Yasushi Izumi, Masaya Akashi, Shoichiro Tsukita, Mikio Furuse
    • Journal Title

      Experimental Cell Research

      Volume: 317 Pages: 413-422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792340
  • [Journal Article] A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions2011

    • Author(s)
      Masaya Akashi, Tomohito Higashi, Sayuri Masuda, Takahide Komori, Mikio Furuse
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 413 Pages: 224-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792340
  • [Presentation] 口腔扁平上皮癌におけるミトコンドリア関連タンパク質発現と分化、転移、予後との関係.2023

    • Author(s)
      村上明希,長谷川巧実,武田大介,廣田純也,黒澤 泉,伊賀利香,八谷奈苗,有本智美,筧 康正,明石昌也
    • Organizer
      第68回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-22K10193
  • [Presentation] がん関連線維芽細胞マーカーの発現抑制に着目した炭酸ガス吸収療法による抗腫瘍効果の検討.2023

    • Author(s)
      田所慶誠, 長谷川巧実, 廣田純也, 村上明希, 佐々木亜紀, 武田大介, 筧 康正, 明石昌也.
    • Organizer
      第68回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-22K10193
  • [Presentation] 局所的炭酸ガス投与による口腔扁平上皮癌の腫瘍免疫抑制に対する改善効果2022

    • Author(s)
      八谷奈苗,長谷川巧実,武田大介,筧 康正,榊原晶子,明石昌也.
    • Organizer
      第76回日本口腔科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-22K10193
  • [Presentation] 血漿メタボローム解析による担癌マウスモデルと口腔扁平上皮癌臨床検体の比較検討2020

    • Author(s)
      山下淳也,木本 明,八谷奈苗,榎本由依,明石昌也
    • Organizer
      第65回 日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-17K11835
  • [Presentation] シンポジウム11「ゴールから始める顎再建」:顎再建―それぞれの患者・それぞれのゴール2020

    • Author(s)
      明石昌也
    • Organizer
      第65回 日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-17K11835
  • [Presentation] 炭酸ガスを使用した効率的な低酸素環境改善による口腔癌の新規治療法の開発と治療抵抗性の改善効果2019

    • Author(s)
      長谷川巧実、武田大介、斉藤 泉、岩田英治、筧康正、榊原晶子、明石昌也、南川勉、古森孝英
    • Organizer
      第37回日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-18K09788
  • [Presentation] 効率的な低酸素環境改善による口腔癌の新規治療法の開発と治療抵抗性の改善効果2018

    • Author(s)
      長谷川巧実、武田大介、斉藤泉、岩田英治、筧 康正、榊原晶子、明石昌也、南川勉、古森孝英
    • Organizer
      第63回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K09788
  • 1.  Hasegawa Takumi (50546497)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 2.  木本 明 (30597167)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  筧 康正 (70772896)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 4.  武田 大介 (80755637)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 5.  古森 孝英 (50251294)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  重岡 学 (20778716)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  Hiroaki Suzuki (10397812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  FURUDOI SHUNGO (00397803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  OGINO CHIAKI (00313693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  近津 大地 (30343122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  渋谷 恭之 (90335430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  高岡 素子 (60310463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  桐田 忠昭 (70201465)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  梅田 正博 (60301280)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  栗田 浩 (10273103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  前田 道徳 (60636546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  榎本 由依 (70823045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  西村 勇哉 (40728218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  有本 智美 (20841042)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  榊原 晶子 (00569866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  後藤 育子 (20757348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  西村 啓佑 (20771497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  明石 健吾 (60792637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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