KUNO Takayoshi 久野高義

Researcher Number	50144564
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2013: 神戸大学, 大学院医学研究科, 教授 2012: 神戸大学, 医学(系)研究科(研究院), 教授 2012: 神戸大学, 医学研究科, 特命教授 2010 – 2011: 神戸大学, 医学研究科, 教授 2010: 神戸大学, 大学院・医学研究科, 教授 … More 2008: 神戸大, 医学(系)研究科(研究院), 教授 2001 – 2007: 神戸大学, 大学院・医学系研究科, 教授 2005 – 2006: 神戸大学, 大学院医学系研究科, 教授 2004: 神戸大学, 医学系研究科, 教授 2001 – 2002: 神戸大学, 医学系研究科, 教授 2001: 神戸大学, 大学院・医学研究科, 教授 1995 – 2000: Kobe University School of Medicine Dept.pharmacol.Professor, 医学部, 教授 1991 – 1994: Kobe Univ. Sch. Med., Associate Professor, 医学部, 助教授 1986 – 1990: 神戸大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General pharmacology / General pharmacology / Neurochemistry/Neuropharmacology / Cell biology Except Principal Investigator Biological Sciences / General pharmacology / General pharmacology / Cell biology / Physical pharmacy / Functional biochemistry / 広領域
Keywords	Principal Investigator カルシニューリン / マップキナーゼ / 分裂酵母 / 細胞内輸送 / 免疫抑制薬 / 蛋白質燐酸化反応 / 細胞質分裂 / 細胞増殖 / カルシウム / バルプロ酸 … More / Rab / 転写因子 / MAP kinase / リン脂質 / GPIアンカー / ユビキチン / ストレス応答 / calcineurin / モデル生物 / ファルネシルトランスフェラーゼ / ファルネシル化 / Cキナーゼ / がん遺伝子 / rab / 低分子量Gタンパク質 / RNA / シグナル伝達 / リン酸化 / RNA結合蛋白質 / 蛋白質燐酸化 / ミオシン重鎖 / スクリーニング / イノシトールりん脂質 / 燐酸化酵素 / ストレス応答機構 / ホスファターゼ / 脱燐酸化酵素 / MAPキナーゼ / 細胞内情報伝達 / 遺伝子 / ストレス蛋白質 / サブタイプ / 免疫組織化学 / カルシニュ-リン / サイクリックAMP / phospholipid / valproic acid / farnesyltransferase / immunosuppressant / アダプチン / 免疫抑制約 / ホスホリパーゼ / イノシトールリン脂質 / 小胞輸送 / 副作用 / GDI / 感受性遺伝子 / マップキナー / phosphatidylinositol / GPI anchor / myosin / intracellular traffic / cytokinesis / immunosuppressants / SIN pathway / Cdc7 / ホスファチジルイノシトール / ミオシン / fission yeast / screening / protein phosphatase / protein phosphorylation / immunosuprressant / プロテインフォスファターゼ / スクリーニング系 / 酸化ストレス / グアニンヌクレオチド交換因子 / 低分子量GTP結合タンパク質 / チャネル / 細胞内カルシウム / 薬剤感受性 / 薬剤耐性 / アゾール系 / コバルト / コレステロール / スタチン / 抗真菌薬 / 薬物スクリーニング / Ras / Rho / 抗がん薬 / 阻害薬 / がん / タンパク質リン酸化 / 低分子量GTP結合たんぱく質 / 制御因子 / ジアシルグリセロール / PI4P5キナーゼ / 細胞内小胞輸送 / GTP結合タンパク質 / 免役抑制薬 / がん転移 / 分子標的薬 / ノックアウト / 細胞形態 / 転写調節 / RNA代謝 / 蛋白質分解 / TypeII ミオシン / Cdc7 kinase / 蛋白質脱リン酸化酵素 / Septation Initiation Network(SIN) / 分裂酵母モデル系 / WDリピート / GTP結合蛋白質 / クロライドイオン / 脱燐酸化反応 / SSE / 出芽酵母 / 蛋白質脱燐酸化酵素 / カルシウムイオン / 神経伝達 / 分子シャペロン / 発芽酵母 / cDNAクローニング / visinin / カルシウム結合蛋白質 / 免疫抑制剤 / 蛋白質脱燐酸化反応 / cDNAクロ-ニング / in situ hybridization / タンパク質脱燐酸化酵素 / プロテインフォスファタ-ゼ / グアニル酸シクラ-ゼ / サイクリックGMP / プロテインキナ-ゼA / 遺伝子工学 / 蛋白質燐酸化酵素 … More Except Principal Investigator カルシニューリン / 免疫抑制薬 / 細胞内輸送 / 分裂酵母 / プロテインキナーゼC / サブタイプ / 細胞質分裂 / プロテインキナ-ゼC / 分子遺伝学 / 酵母モデル生物 / MAPキナーゼ / 分裂酵母モデル系 / NVP / 細胞内情報伝達 / Calcineurin / 免疫組織化学 / Protein kinase C / 低分子量Gタンパク質 / タンパク質リン酸化 / 特異的免疫抑制薬 / GPIアンカー / 蛋白質リン酸化反応 / カルシニュ-リン / Cloning / 制御サブユニット / クローニング / cytokinesis / fission yeast / immunosuppressants / calcineurin / SHP-2 / SHPS-1 / オカダ酸 / エンドサイトーシス / FK506 / 長期増強 / Protein phosphatase / Protein Kinase / 神経細胞 / cDNAクロ-ニング / 脱燐酸化反応 / 蛋白質燐酸化反応 / アダプチン / モデル生物 / 薬物感受性 / バルプロ酸 / カルシウムシグナル / RNA結合タンパク質 / シグナル伝達 / 蛋白質脱リン酸化 / MAPキナーゼホスファターゼ / タンパク質脱燐酸化酵素 / SIN / 低分子量GTP結合タンパク質 / イノシトールリン脂質 / リピッドキナーゼ / cDNAクローニング / アルツハイマー病 / GABA_B受容体 / プロテインキナ-ゼ / Electron microscopy / Immunocytochemistry / Central nervous system / Subspecies / 電子顕微鏡 / 中枢神経系 / クロ-ニング / Immunohistochemistry / Cellular signal transduction / Neurotransmission / Synaptic transmission / cAMP-dependent protein kinase / cAMP結合部位 / cAMP依存性プロテインキナーゼ / 神経情報伝達 / シナプス伝達 / cAMP依存性プロテインキナ-ゼ / Peptide / Corneum / Drug Delivery System(DDS) / Cyclosporin A / Insulin / Percutaneous Absorption / Scrotum / ドラッグデリバリーシステム / 角質層 / ペプチドの投与法 / DDS / エイゾン / シクロスポリンA / インスリン / 経皮吸収 / 陰嚢 / subtype cAMP-dependent protein kinase / Protein kinaseC / molecular biology / Neuropeptide / Dopamine / 組換えDNA / in situ mRNA cDNA hybridization / ノザーンブロット / アンギオテンシノーゲンcDNA / アンギオテンシノーゲン / サイクリックAMP依存生蛋白質燐酸化酵素 / 遺伝子工学 / ニューロペプチド / ドパミン / small GTPase / adaptin / membrane traffic / tacrolimus / ENTHドメイン / エンドゾーム / ゴルジ体 / Mn^<2+>ホメオスタシス / Mn^<2+>-ATPase / Ca^<2+> / Rho / ホスフォリパーゼC / グルカン合成酵素阻害薬 / PI4P5K / エンドソーム / ゴルジ / Ypt3 / Ryh1 / イオンホメオスタシス / トランスポーター / MAP kinase / RNA-binding protein / membrane trafficking / phosphorylation / immunosuppressant / 免疫抑制薬FK506 / 低分子量GTP結合蛋白質 / 転写因子 / マップキナーゼ / ゲノム薬理学 / 変異体 / タンパク質脱リン酸化 / lipid kinase / cell wall integrity / vesicular trafficking / protein dephosphorylation / 細胞壁形成 / タンパク質脱リン酸化酵素 / B cell antigen receptor / Tautomycin / Tyrosine protein phosphatase / threonine protein phosphatase / Serine / Signal transduction / CD45 / ノジュラリン / B細胞抗原受容体 / トウトマイシン / チロシンホスファターゼ / トレオニンホスファターゼ / セリン / プロテインホスファターゼ / neurocalcin / recoverin / Hippocalcin / S-modulin / Neuron / calcium-binding proteins / 神経 / リン酸化 / カルモジュリン / S-モジュリン / ニューロカルシン / カルモジェリン / リカバリン / ヒポカルシン / S-モジェリン / カルシウム結合蛋白質 / Neural visinin-like calcium-binding proteins / Endocytosis / Lipid kinase / Adaptin / Long-term potentiation / GABA transporter / 脱燐酸化酵素阻害薬 / カリクリン-A / NVP-1 / visinin / カルシウム動員 / NG108-15細胞 / CA1 / セロトニン遊離 / カリクリンA / Ca^<2+>結合蛋白質 / リピットキナーゼ / GΛT / Subtype / Expression / GABA_B receptor / Protein Kinase A / Protein Kinase C / 大量発現 / プロテインフォスファターゼ / 発現 / プロテインキナーゼA / プロテインキナーゼ / cDNA Cloning / Neurotransmitter / Synapse Formation / Dephosphorylation / Protein Phosphorylation / 蛋白質脱燐酸化酵素 / 蛋白質燐酸化酵素 / 神経伝達物質 / シナプス形成 / 薬物相互作用 / 薬物副作用 / 細胞膜輸送 / メンブレン・トラフィック / 薬物耐性 / Golgi / AP-1複合体 / phosphatidyl inositol transfer protein / Rab GDI / 低分子量Gタンパク質Rab / セプチン / がん化抑制因子 / 減数分裂 / mRNA安定性 / RNA結合蛋白質 / Type II ミオシン / Cdc7 kinase / 低分子量GTP結合蛋白質Rab / Septation Initiation Network (SIN) / プロテオミクス / PIP2 / GPIアンカー合成酵素 / 蛋白質脱リン酸化酵素 / イノシトール代謝 / β-アダプチン / 細胞内小胞輸送 / its変異株 / FK506(タクロリムス) / ロイジンジッパー / J領域 / 分子シャペロン / ストレス蛋白質 / DnaJファミリー / PGP9.5 / Levy小体 / ユビキチンC末端加水分解酵素 / paired helical filament / ユビキチン / プロテインホスファタ-ゼ / 神経細胞死 / 細胞内Ca^<2+>濃度 Less

Elucidation of the molecular mechanism by which valproic acid affects intracellular membrane traffic
- Principal Investigator
  
  MA YAN
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Pharmacogenomic study on the drug-sensitive genes using model organismsPrincipal Investigator
- Principal Investigator
  
  KUNO Takayoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Identification of Molecular Targets for Valproic Acid in Membrane Transport System Using Fission Yeast Model Organism
- Principal Investigator
  
  MA Yan
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
がん細胞増殖シグナル制御機構の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
モデル生物を用いた薬物感受性遺伝子に関するゲノム薬理学的研究Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
マップキナーゼ経路の新規制御因子・阻害薬の分子遺伝学的スクリーニングPrincipal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
マップキナーゼ経路の新規制御神子・阻害薬の分子遺伝学的スクリーニングPrincipal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
カルシウムシグナルによるタンパク質の産生・輸送・分解の制御機構Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
カルシニューリンとの拮抗的関係を利用したマップキナーゼ経路の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
カルシウムシグナルによる細胞質分裂制御機構の解明
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
細胞内輸送に関わるカルシウムシグナル伝達経路の分子遺伝学的解析
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
Genomic analysis of calcineurin using fission yeast as a model system
- Principal Investigator
  
  SHUNTOH Hisato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe Gakuin University
  Kobe University
カルシニューリンとの拮抗的関係を利用したマップキナーゼ経路の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
RNA結合タンパク質を介したMAPキナーゼシグナルの制御に関する分子遺伝学的研究
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
  Kobe University
カルシウムシグナルによるタンパク質の産生・輸送・分解の制御機構Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Identification of immunosuppressant-sensitive genes: a study using model organismsPrincipal Investigator
- Principal Investigator
  
  KUNO Takayoshi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
モデル生物を用いたカルシニューリン経路の分子機構に関する機能ゲノム学的解析
- Principal Investigator
  
  春藤久人
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
カルシニューリンとの拮抗的関係を利用したマップキナーゼ経路の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
分裂酵母モデル系を用いた細胞質分裂制御機構の解明
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
RNA結合蛋白質を介した新規シグナル伝達系の分子遺伝学的研究
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
カルシウムシグナルによるユビキチン系制御機構の分子遺伝学的解明Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Functional analysis of calcineurin-mediated signalling pathways using fission yeast as a model organism
- Principal Investigator
  
  SUGIURA Reiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kinki University
  Kobe University
分裂酵母モデル系を用いた細胞質分裂制御機構の解明Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
モデル生物を用いたカルシニューリン経路の分子機構に関する機能ゲノム学的解析
- Principal Investigator
  
  春藤久人
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
分裂酵母モデル系を用いたマップキナーゼ制御機構の解明Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
モデル生物を用いたカルシニューリン経路の分子機構に関する機能ゲノム学的解析
- Principal Investigator
  
  春藤久人
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
分裂酵母モデル系を用いたマップキナーゼ制御機構の解明Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
分裂酵母モデル系を用いたカルシニューリンシグナル伝達機構と標的遺伝子群の機能解析
- Principal Investigator
  
  杉浦麗子
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
Pharmacogenomic research on the immunosuppressant sensitivity using model organismsPrincipal Investigator
- Principal Investigator
  
  KUNO Takayoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Functional analysis of calcineurin using fission yeast as a model system
- Principal Investigator
  
  SHUNTOH Hisato
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
分裂酵母モデル系を用いたストレス応答機構の解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
分裂酵母モデル系を用いたストレス応答機構の解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
分裂酵母モデル系を用いたストレス応答機構の解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
ESTABLISHMENT OF HIGH-THROUGHPUT SCREENING FOR IMMUNOSUPPRESSANTS USING YEAST MODEL SYSTEMPrincipal Investigator
- Principal Investigator
  
  KUNO Takayoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
免疫抑制薬の新しい作用点に関する分子遺伝学的研究
- Principal Investigator
  
  春藤久人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
カルシニューリンと機能的に関連する遺伝子の探索、同定及び解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
Physiological significance of protein phosphatases on cellular signal transduction
- Principal Investigator
  
  TAKEDA Masao
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIROSHIMA UNIVERSITY
新しい酵母ストレス蛋白質SSE1の機能解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
細胞質分裂におけるカルシニューリンの機能と関連遺伝子の単離Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Structure and Function of Novel Neuron-specific Calcium-binding Proteins
- Principal Investigator
  
  KAWAMURA Satoru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Graduate School of Science, Osaka University
新しい酵母ストレス蛋白質遺伝子SSEIの機能解析Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
哺乳動物のDnaJホモローグのクローニングと生理機能の解明
- Principal Investigator
  
  SHUNTOH Hisato
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
神経情報伝達におけるカルシニューリン分子多様性の意義Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kobe University
新しい神経特異的カルシウム結合蛋白質(NVP遺伝子ファミリー)の構造と機能Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kobe University
Screening of drugs for neurodegenerative disorders using neurotransmitter release machinery expressed in Xenopus oocytes
- Principal Investigator
  
  SHUNTOH Hisato
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
アルツハイマー病脳内蓄積物質形成におけるユビキチンC末端加水分解酵素の役割
- Principal Investigator
  
  田中千賀子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
カルシニューリンを介した蛋白質脱燐酸化反応の細胞内情報伝達における役割の解明Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
MPTPおよび興奮性アミノ酸による神経細胞死とその防御機構に関する研究
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
神経情報伝達におけるカルシニュ-リンサブタイプの役割に関する研究Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Establishment of cell lines which specifically express a subtype of protein kinases and protein phosphatases and its application
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University School of Medicine
cAMPによる細胞内Ca濃度調節機構:Aキナ-ゼ変異体を用いた細胞工学的研究Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
The Role of Protein Phosphorylation and dephosphorylation in Neuronal Signal Transduction
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
細胞内セカンドメッセンジャ-間相互作用の遺伝子工学的研究Principal Investigator
- Principal Investigator
  
  久野高義
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Structure and Function of Protein Kinases: Molecular Mechanism of Neuronal Signal Transduction
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University School of Medicine
Electron microscopic immunocytochemistry of protein kinase C using subspecies-specific anti-peptide antibody
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University School of Medicine
Drug Delivery System of Insulin and Calcitonin through the Scrotum of Rats.
- Principal Investigator
  
  OKUMURA Katsuhiko
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kobe University
Molecular biologocal studies on the regulation of neuropeptide synthesis by dopamine
- Principal Investigator
  
  TNAKA Chikako
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University

All 2013 2012 2011 2010 2009 2006 2005 2004 2003 2002

All Journal Article Presentation Patent

[Journal Article] A Genome-Wide Screening of Potential Target Genes to Enhance the Antifungal Activity of Micafungin in Schizosaccharomyces pombe2013
- Author(s)
  Xin Zhou, Yan Ma, Yue Fang, Wugan gerile, Wurentuya Jaiseng, Yuki Yamada, Takayoshi Kuno
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 5 Pages: e65904-e65904
- DOI
  10.1371/journal.pone.0065904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790251
[Journal Article] A Genome-Wide Screening of Potential Target Genes to Enhance the Antifungal Activity of Micafungin in Schizosaccharomyces pombe2013
- Author(s)
  Xin Zhou, Yan Ma, Yue Fang, Wugan gerile, Wurentuya Jaiseng, Yuki Yamada, and Takayoshi Kuno
- Journal Title
  
  PLoS ONE
  
  Volume: 8(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790251
[Journal Article] A Genetic and Pharmacological Analysis of Isoprenoid Pathway by LC-MS/MS in Fission Yeast2012
- Author(s)
  Tomonori Takami
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 11 Pages: e49004-e49004
- DOI
  10.1371/journal.pone.0049004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390048, KAKENHI-PROJECT-24790251
[Journal Article] Genetic screening for regulators of Prz1, a transcriptional factor acting downstream of calcineurin in fission yeast2012
- Author(s)
  Atsushi Koike, Toshiaki Kato, Reiko Sugiura, Yan Ma, Yuki Tabata, Koji Ohmoto, Susie O. Sio, Takayoshi Kuno
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 23 Pages: 19294-19303
- DOI
  10.1074/jbc.m111.310615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390048, KAKENHI-PROJECT-23390021, KAKENHI-PROJECT-24790251
[Journal Article] A measurable activation of the bZIP transcription factor Atf1 in a fission yeast strain devoid of stress-activated and cell-integrity MAPK activities2012
- Author(s)
  Xin Zhou, Yan Ma, Toshiaki Kato, and Takayoshi Kuno
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287(28) Pages: 23434-23439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790251
[Journal Article] A measurable activation of the bZIP transcription factor Atf1 in a fission yeast strain devoid of stress-activated and cell-integrity MAPK activities.2012
- Author(s)
  Xin Zhou, Yan Ma, Toshiaki Kato, and Takayoshi Kuno
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 28 Pages: 23434-23439
- DOI
  10.1074/jbc.c111.338715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790251
[Journal Article] Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast2012
- Author(s)
  Ryuko S, Ma Y, Ma N, Sakaue M, Kuno T
- Journal Title
  
  Mol Genet Genomics
  
  Volume: 287(8):651-62 Issue: 8 Pages: 651-62
- DOI
  10.1007/s00438-012-0705-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300262, KAKENHI-PROJECT-22390048, KAKENHI-PROJECT-24650495, KAKENHI-PROJECT-24790251
[Journal Article] Studies on the Roles of Clathrin-Mediated Membrane Trafficking and Zinc Transporter Cis4 in the Transport of GPI-Anchored Proteins in Fission Yeast2012
- Author(s)
  Jaiseng W, Fang Y, Ma Y, Sugiura R, Kuno T
- Journal Title
  
  PLoS ONE
  
  Volume: 7(7) Issue: 7 Pages: 19294-19303
- DOI
  10.1371/journal.pone.0041946
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20112008, KAKENHI-PROJECT-22390048, KAKENHI-PROJECT-23390021, KAKENHI-PROJECT-24790251
[Journal Article] Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast2012
- Author(s)
  Sayomi Ryuko, Yan Ma, Ning Ma, Motoyoshi Sakaue, and Takayoshi Kuno
- Journal Title
  
  Mol Genet Genomics
  
  Volume: 287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790251
[Journal Article] Genome-Wide Screening for Genes Associated with FK506 Sensitivity in Fission Yeast2011
- Author(s)
  Yan Ma, Weijuan Jiang, Qingbin Liu, Sayomi Ryuko, Takayoshi Kuno
- Journal Title
  
  PLoS ONE
  
  Volume: 6(8) Issue: 8 Pages: e23422-e23422
- DOI
  10.1371/journal.pone.0023422
- NAID
  120005468181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390048
[Journal Article] MAPKKK-dependent and -independent activation of Sty1 stress MAPK in fission yeast.2010
- Author(s)
  Xin Zhou, Yan Ma, Reiko Sugiura, Daiki Kobayashi, Masahiro Suzuki, Lu Deng, Takayoshi Kuno
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 32818-32823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.2010
- Author(s)
  Yan Ma, Reiko Sugiura, Lili Zhang, Xin Zhou, Mai Takeuchi, Yi He, Takayoshi Kuno
- Journal Title
  
  Mol.Genet.Genomics 284(3)
  
  Pages: 161-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.2010
- Author(s)
  Yan Ma, Reiko Sugiura, Lili Zhang, Xin Zhou, Mai Takeuchi, Yi He, Takayoshi Kuno
- Journal Title
  
  Mol.Genet.Genomics
  
  Volume: 284 Pages: 161-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] MAPKKK-dependent and -independent activation of Sty1 stress MAPK in fission yeast.2010
- Author(s)
  Xin Zhou, Yan Ma, Reiko Sugiura, Daiki Kobayashi, Masahiro Suzuki, Lu Deng, Takayoshi Kuno
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 32818-32823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast.2009
- Author(s)
  Yan Ma, Mai Takeuchi, Reiko Sugiura, Susie O.Sio, Takayoshi Kuno
- Journal Title
  
  Genes Cells 14
  
  Pages: 1015-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] Deletion mutants of of AP-1 adaptin subunits display distinct phenotypes in fission yeast2009
- Author(s)
  Yan Ma, Mai Takeuchi, Reiko Sugiura, Susie O.Sio, Takayoshi Kuno
- Journal Title
  
  Genes to Cells 14
  
  Pages: 1015-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790241
[Journal Article] Genetic and Functional Interaction between Ryh1 and Ypt3 : two Rab GTPases that Function in S.pombe Secretory Pathway.2006
- Author(s)
  Yi He, Reiko Sugiura, Yan Ma, Ayako Kita, Lu Deng, Kaoru Takegawa, Hisato Shuntoh, Takayoshi Kuno
- Journal Title
  
  Genes-Cells (in press.)
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] Genetic and Functional Interaction between Ryh1 and Ypt3 : two Rab GTPases that Function in S.pombe Secretory Pathway.2006
- Author(s)
  Yi He, Reiko Sugiura, Yan Ma, Ayako Kita, Lu Deng, Kaoru Takegawa, Hisato Shuntoh, Takayoshi Kuno
- Journal Title
  
  Genes-Cells (in press.)
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] Comparison of Toxicity and Toxicokinetics/Pharmacokinetics of an α1L-adrenoceptor Agonist in Rats and Rhesus monkeys.2005
- Author(s)
  Matsumaru T, Sugiura R, Sakai K, Igarashi T, Kuno T
- Journal Title
  
  J.Pharmacol.Sci. 97(2)
  
  Pages: 273-283
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] Comparison of Toxicity and Toxicokinetics/Pharmacokinetics of an α1L-adrenoceptor Agonist in Rats and Rhesus monkeys.2005
- Author(s)
  Matsumaru T, Sugiura R, Sakai K, Igarashi T, Kuno T
- Journal Title
  
  J.Pharmacol.Sci. 97(2)
  
  Pages: 273-283
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] Phosphatidylinositol-4-phosphate-5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway.2005
- Author(s)
  Lu Deng, Reiko Sugiura, Kazuki Ohta, Kazuki Tada, Masahiro Suzuki, Masato Hirata, Hisato Shuntoh, Takayoshi Kuno
- Journal Title
  
  J.Biol.Chem. 280(30)
  
  Pages: 27561-27568
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity.2005
- Author(s)
  Sio SO, Suehiro T, Sugiura R, Takeuchi M, Mukai H, Kuno T
- Journal Title
  
  J.Biol.Chem. 280(13):
  
  Pages: 12231-12238
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] Phosphatidylinositol-4-phosphate-5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway.2005
- Author(s)
  Lu Deng, Reiko Sugiura, Kazuki Ohta, Kazuki Tada, Masahiro Suzuki, Masato Hirata, Hisato Shuntoh, Takayoshi Kuno
- Journal Title
  
  J.Biol.Chem. 280(30)
  
  Pages: 27561-27568
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity.2005
- Author(s)
  Sio SO, Suehiro T, Sugiura R, Takeuchi M, Mukai H, Kuno T
- Journal Title
  
  J.Biol.Chem. 280(13):
  
  Pages: 12231-12238
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] Loss of Apm1, the AP-1 Clathrin-Adaptor mul Subunit, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast2004
- Author(s)
  Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO, Takegawa K, Sakaue M, Shuntoh H, Kuno T
- Journal Title
  
  Mol Biol Cell. 15.6
  
  Pages: 2920-2931
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Upregulation of mRNA in MAPK Signaling Transcriptional Activation or mRNA Stabilization?2004
- Author(s)
  Sugiura R, Kita A, Kuno T.
- Journal Title
  
  Cell Cycle. 3(3) Mar
  
  Pages: 286-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Lubl Participates in Ubiquitin Homeostasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T
- Journal Title
  
  Mol Cell Biol. 24.6
  
  Pages: 2324-2331
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Lub1 Participates in Ubiquitin Homeostasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T
- Journal Title
  
  Mol Cell Biol. 24.6
  
  Pages: 2324-2331
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] Pmrl, a P-type ATPase, and Pdt1, an Nramp Homolog, Cooperatively Regulate Cell Morphogenesis in Fission Yeast : The Importance of Mn2+ Homeostasis.2004
- Author(s)
  Maeda-T, Sugiura-R, Kita-A, Saito-M, Deng-L, He-Y, Lu-Y, Fujita-Y, Takegawa-K, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells 9(1)
  
  Pages: 71-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Lub1 Participates in Ubiquitin Homeostasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T
- Journal Title
  
  Mol Cell Biol. 24.6
  
  Pages: 2324-2331
- Data Source
  KAKENHI-PROJECT-15030229
[Journal Article] Loss of Apm1,the AP-1 Clathrin-Adaptor mu1 Subunit, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast2004
- Author(s)
  Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO, Takegawa K, Sakaue M, Shuntoh H, Kuno T
- Journal Title
  
  Mol Biol Cell. 15.6
  
  Pages: 2920-2931
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] Loss of Apm1,the AP-1 Clathrin-Adaptor mu1 Subunit, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast2004
- Author(s)
  Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio So, Takegawa K, Sakaue M, Shuntoh H, Kuno T
- Journal Title
  
  Mol Biol Cell. 15.6
  
  Pages: 2920-2931
- Data Source
  KAKENHI-PROJECT-16026221
[Journal Article] Loss of Apm1, the AP-1 Clathrin-Adaptor mu1 Subunit, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast2004
- Author(s)
  Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO, Takegawa K, Sakaue M, Shuntoh H, Kuno T
- Journal Title
  
  Mol Biol Cell. 15(6) Jun
  
  Pages: 2920-2931
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Upregulation of mRNA in MAPK Signaling : Transcriptional Activation or mRNA Stabilization?2004
- Author(s)
  Sugiura R, Kita A, Kuno T.
- Journal Title
  
  Cell Cycle 3(3)
  
  Pages: 286-288
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Loss of Apm1, the AP-1 Clathrin-Adaptor mu1 Subunit, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast2004
- Author(s)
  Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO, Takegawa K, Sakaue M, Shuntoh H, Kuno T
- Journal Title
  
  Mol Biol Cell. 15.6
  
  Pages: 2920-2931
- Data Source
  KAKENHI-PROJECT-15030229
[Journal Article] Lub1 Participates in Ubiquitin Homeostasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T
- Journal Title
  
  Mol Cell Biol. 24.6
  
  Pages: 2324-2331
- Data Source
  KAKENHI-PROJECT-16044231
[Journal Article] Pmr1, a P-type ATPase, and Pdt1, an Nramp Homolog, Cooperatively Regulate Cell Morphogenesis in Fission Yeast : The Importance of Mn2+ Homeostasis.2004
- Author(s)
  Maeda-T, Sugiura-R, Kita-A, Saito-M, Deng-L, He-Y, Lu-Y, Fujita-Y, Takegawa-K, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells 9(1) Jan
  
  Pages: 71-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Calcineurin phosphatase in signal transduction : lessons from fission yeast.2004
- Author(s)
  Sugiura-R, Sio-SO, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells 7(7)
  
  Pages: 619-627
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Lub1 Participates in Ubiquitin Homeostasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T.
- Journal Title
  
  Mol Cell Biol. 15;24(6) Mar
  
  Pages: 2324-2331
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Lub1 Participates in Ubiquitin Homeoslasis and Stress Response via Maintenance of Cellular Ubiquitin Contents in Fission Yeast.2004
- Author(s)
  Ogiso Y, Sugiura R, Kamo T, Yanagiya S, Lu Y, Okazaki K, Shuntoh H, Kuno T.
- Journal Title
  
  Mol Cell Biol 15(6)
  
  Pages: 2324-2331
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Feedback regulation of MAPK signalling by an RNA-binding protein.2003
- Author(s)
  Sugiura-R, Kita-A, Shimizu-Y, Shuntoh-H, Sio-SO, Kuno-T.
- Journal Title
  
  Nature 424(6951) August
  
  Pages: 961-965
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] IDENTIFICATION OF DISTINCT BRANCHES OF CALCINEURIN SIGNALING PATHWAY IN FISSION YEAST.2003
- Author(s)
  Hirayama-S, Sugiura-R, Lu-Y, Maeda-T, Kawagishi-K, Yokoyama-M, Tohda-H, Giga-Hama-Y, Shuntoh-H, Kuno-T.
- Journal Title
  
  J-Biol-Chem. 278(20) May
  
  Pages: 18078-18084
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Zinc Finger Protein Prz1 Regulates Ca2+ but Not Cl- Homeostasis in Fission Yeast.2003
- Author(s)
  Hirayama-S, Sugiura-R, Lu-Y, Maeda-T, Kawagishi-K, Yokoyama-M, Tohda-H, Giga-Hama-Y, Shuntoh-H, Kuno-T.
- Journal Title
  
  J-Biol-Chem 278(20)
  
  Pages: 18078-18084
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Feedback regulation of MAPK signalling by an RNA-binding protein.2003
- Author(s)
  Sugiura-R, Kita-A, Shimizu-Y, Shuntoh-H, Sio-SO, Kuno-T.
- Journal Title
  
  Nature 424(6951)
  
  Pages: 961-965
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Calcineurin is implicated in the regulation of the septation initiation network in fission yeast.2002
- Author(s)
  Lu-Y, Sugiura-R, Yada-T, Cheng-H, Sio-SO, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells. 7(10) Oct
  
  Pages: 1009-1019
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Calcineurin phosphatase in signal transduction : lessons from fission yeast.2002
- Author(s)
  Sugiura-R, Sio-SO, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells 7(7) Jul
  
  Pages: 619-627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Calcineurin is implicated in the regulation of the septation initiation network in fission yeast.2002
- Author(s)
  Lu-Y, Sugiura-R, Yada-T, Cheng-H, Sio-SO, Shuntoh-H, Kuno-T
- Journal Title
  
  Genes-Cells 7(10)
  
  Pages: 1009-1019
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Genetic interaction between calcineurin and type 2 myosin and their involvement in the regulation of cytokinesis and chloride ion homeostasis in fission yeast.2002
- Author(s)
  Fujita-M, Sugiura-R, Lu-Y, Xu-L, Xia-Y, Shuntoh-H, Kuno-T
- Journal Title
  
  Genetics 161 Jul
  
  Pages: 971-981
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway, and its connection to calcineurin function.2002
- Author(s)
  Cheng-H, Sugiura-R, Wu-W, Fujita-M, Lu-Y, Sio-SO, Kawai-R, Takegawa-K, Shuntoh-H, Kuno-T
- Journal Title
  
  Mol-Biol-Cell 13(6)
  
  Pages: 2963-2976
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Journal Article] Genetic interaction between calcineurin and type 2 myosin and their involvement in the regulation of cytokinesis and chloride ion homeostasis in fission yeast.2002
- Author(s)
  Sugiura R, Kita A, Kuno T.
- Journal Title
  
  Genetics 161(3)
  
  Pages: 971-981
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580698
[Patent] 新規栄養要求性分裂酵母2004
- Inventor(s)
  久野高義, 杉浦麗子, 斉藤真理子, 小池敦資
- Industrial Property Rights Holder
  財団法人新産業創造研究機構
- Industrial Property Number
  2004-310061
- Filing Date
  2004-10-25
- Data Source
  KAKENHI-PROJECT-16022241
[Patent] 新規栄養要求性分裂酵母2004
- Inventor(s)
  久野高義, 杉浦麗子, 斉藤真理子, 小池敦資
- Industrial Property Rights Holder
  財団法人新産業創造研究機構
- Industrial Property Number
  2004-310061
- Filing Date
  2004-10-25
- Data Source
  KAKENHI-PROJECT-15209010
[Patent] 新規栄養要求性分裂酵母2004
- Inventor(s)
  久野高義, 杉浦麗子, 斉藤真理子, 小池敦資
- Industrial Property Rights Holder
  財団法人新産業創造研究機構
- Industrial Property Number
  2004-310061
- Filing Date
  2004-10-25
- Data Source
  KAKENHI-PROJECT-15032231
[Presentation] ラパマイシン標的分子Tor2制御におけるNpr2の役割：ゲノムワイド解析による解明2013
- Author(s)
  馬艶、馬寧、劉慶彬、張麗麗、福間久友、西島数人、久野高義
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] ラパマイシン標的分子Tor2制御におけるNpr2の役割 : ゲノムワイド解析による解明2013
- Author(s)
  馬艶, 馬寧, 劉慶彬, 張麗麗, 福間久友, 西島数人, 久野高義
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] Feedback regulation of TORC1 signaling by Npr2, but not by Tsc22013
- Author(s)
  Yan Ma, Ning Ma, Qingbin Liu, Lili Zhang, Elizabeth Henske, Takayoshi Kuno
- Organizer
  EMBO Conference on Fission Yeast: pombe 2013, 7th International Fission Yeast Meeting
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] Feedback regulation of TORC1 signaling by Npr2, but not by Tsc22013
- Author(s)
  Yan Ma, Ning Ma, Qingbin Liu, Lili Zhang, Elizabeth Henske, Takayoshi Kuno
- Organizer
  EMBO Conference on Fission Yeast : pombe 2013, 7th International Fission Yeast Meeting
- Place of Presentation
  London, United Kingdom
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母ノックアウトライブラリーを用いた亜鉛感受性及び耐性遺伝子のゲノムワイドスクリーニング2012
- Author(s)
  長谷川よしの, 柳幸佐代美, 馬艶, 久野高義
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母におけるDNA 損傷応答メカニズムの解明2012
- Author(s)
  山田優希、烏干格日楽、Xin Zhou、馬艶、久野高義
- Organizer
  第122回　日本薬理学会近畿部会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母ノックアウトライブラリーを用いたバルプロ酸感受性遺伝子の探索と解析2012
- Author(s)
  張麗麗、馬艶、馬寧、劉慶彬、久野高義
- Organizer
  第122回　日本薬理学会近畿部会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母ノックアウトライブラリーを用いた亜鉛感受性及び耐性遺伝子のゲノムワイドスクリーニング2012
- Author(s)
  長谷川よしの、柳幸佐代美、馬艶、久野高義
- Organizer
  第122回　日本薬理学会近畿部会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母におけるNO応答転写調節メカニズムの解明2012
- Author(s)
  烏干格日楽, 山田優希, 加藤俊明, Xin Zhou, 馬艶, 久野高義
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母におけるNO応答転写調節メカニズムの解明2012
- Author(s)
  烏干格日楽、山田優希、加藤俊明、Xin Zhou、馬艶、久野高義
- Organizer
  第122回　日本薬理学会近畿部会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母ノックアウトライブラリーを用いたバルプロ酸感受性遺伝子の探索と解析2012
- Author(s)
  張麗麗, 馬艶, 馬寧, 劉慶彬, 久野高義
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 分裂酵母におけるDNA損傷応答メカニズムの解明2012
- Author(s)
  山田優希, 烏干格日楽, Xin Zhou, 馬艶, 久野高義
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790251
[Presentation] 低グルコースで活性化される転写因子Rst2の転写活性のリアルタイムモニタリング2012
- Author(s)
  加藤俊明, 馬艶, 久野高義
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24790251

1. SHUNTOH Hisato (70206259)

# of Collaborated Projects: 30 results

# of Collaborated Products: 27 results
2. SUGIURA Reiko (90294206)

# of Collaborated Projects: 20 results

# of Collaborated Products: 35 results
3. TANAKA Chikako (20025571)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. SAITO Naoaki (60178499)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. TANIYAMA Kohtaro (70030898)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. MA Yan (70457050)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
7. 石渡俊二 (20301054)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 喜多綾子 (00388498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. MUKAI Hideyuki (80252758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWAMURA Satoru (80138122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIDAKA Hiroyoshi (80100171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIKI Naomasa (40094445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOKUNAGA Fumio (80025452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAMATSU Ken (90154898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKEDA Masao (40030853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAKURA Hidetaka (60166486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KASUGA Masato (50161047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIYAMOTO Eishichi (50109659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAMURA Shinri (20124604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KIKUCHI Kunimi (20006117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. OKUMURA Katsuhiko (60025707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NISHIZUKA Yasutomi (10025546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 日野田裕治 (10165128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 渡邊利雄 (60201208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KASE Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. TAMURA Kouichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 坂上元祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUNO Takayoshi 久野 高義

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Pharmacogenomic study on the drug-sensitive genes using model organismsPrincipal Investigator

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がん細胞増殖シグナル制御機構の分子遺伝学的解析Principal Investigator

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モデル生物を用いた薬物感受性遺伝子に関するゲノム薬理学的研究Principal Investigator

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マップキナーゼ経路の新規制御因子・阻害薬の分子遺伝学的スクリーニングPrincipal Investigator

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マップキナーゼ経路の新規制御神子・阻害薬の分子遺伝学的スクリーニングPrincipal Investigator

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カルシウムシグナルによるタンパク質の産生・輸送・分解の制御機構Principal Investigator

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カルシニューリンとの拮抗的関係を利用したマップキナーゼ経路の分子遺伝学的解析Principal Investigator

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カルシニューリンとの拮抗的関係を利用したマップキナーゼ経路の分子遺伝学的解析Principal Investigator

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KUNO Takayoshi 久野高義