TASAKA Keiichi 田坂慶一

… Alternative Names

田坂慶一タサカケイイチ

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Researcher Number	50155058
Other IDs
Affiliation (based on the past Project Information) *help	2008: 大阪大学, 医学系研究科, 准教授 2000 – 2006: 大阪大学, 医学系研究科, 助教授 1997: Osaka University Medical School, Lecturer, 医学部, 講師 1997: 阪大, 医学部, 助手 1992 – 1996: 大阪大学, 医学部, 助手 1988: 大阪大学, 医学部, 助手 1986: 大阪大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences
Keywords	Principal Investigator GnRH / Rho / 下垂体 / GH / PRL / LH / FSH / TRH / hypoxia-inducible factor / 卵巣癌 … More / ゴナドトロピン / Rab / Rabphilin / SNAP-25 / FRET / アクチビン / CRH / GHRH / 細胞内カルシウムイオン / activin / エストロゲン / 脂質代謝 / Lipoprotein Lipase / ERα / マトリツクスメタロプロテイネース / マトリックスメタロプロテイネー / 肥満 / 動脈硬化 / LPL / Estrogen / lipoprotein lipase / ER-α / matrix metalloproteinase / 胞胚 / 絨毛 / 低酸素 / 播種 / hypoxia-inducible factor 1α / ES細胞 / 卵 / グリーンマウス / マトリゲル / blastcyst / chirion / low-oxygen condition / ovarian cancer / dissemination / トランスフォ-ミング成長因子α / 上皮成長因子 / 上皮成長因子受容体 / ノザン解析 / 免疫組織化学 / 層細胞培養 / オ-トクライン増殖制御機構 / TGFα / EGF receptor / autocrine growth / nudeマウス / 顎下腺 / sialoadenectomy / EGF受容体 / メッセンジャ-RNA / ノ-ザンブロッティング / 成長因子(grouth factor) / ガン遺伝子(oncogene) / v-erb-B / pE7 / Dot blotting / Transforming growth factor alpha / Epidermal growth factor / Epidermal growth factor receptor / Northern analysis / Immunocytochemistry / Monolayer cell culture / Autocrine growth mechanism … More Except Principal Investigator 絨毛細胞 / 転写制御 / エストロゲン / lipoprotein lipase / LH / 転写因子 / Id-1 / EGF / estrogen / trophoblast / Rho-kinase / プロラクチン / 胎盤 / インテグリン / マイクロアレイ / ラロキシフェン / HUVEC / プロモーターマイクロアレイ / エストロゲン受容体 / アポトーシス / SOD / 子宮筋 / 肥満 / deletion mutants / 変異遺伝子 / 閉経 / 脂質代謝 / obesity / transcriptional regulation / transcription factor / CINC / FS cell / Chemokine / TtT / Oct3 / 4 / hCG / GLUT1 / HIF / BMP-4 / RhoA / apoptosis / survival factor / ERα / Akt / Rho / TRH / ドーパミン / TRHレセプター / 視床下部 / インターロイキン8 / 下垂体 / マウス / Activin / Inhibin / sIL-6R / Leptin / cAMP / 細胞分化 / 転写調節機構 / SP-1 / NF-1 / シスプラチン耐性 / タキソール耐性 / マウス卵巣癌モデル / シグナル伝達関連因子 / アポトーシス関連因子 / ERK経路 / Akt経路 / BAD / 浸潤能 / PKC(protein kinase C) / CRE(cyclic AMP responsive element) / 選択的エストロゲン受容体調節薬 / siRNA / co-regulator / MCF-7細胞 / ヒト血管平滑筋細胞 / CHIP / Co-activator / Co-repressor / co-activator / co-repressor / 乳腺 / 血管内皮 / 血管平滑筋 / 卵巣癌 / 薬剤反応性 / シグナル伝達 / トランスレーショナルリサーチ / 癌 / シスプラチン / タキソール / NFkB / SiRNA / IAPファミリー / アデノウイルス / ス-パオキシド / プロスタグランディン / 細胞内カルシウムイオン / 細胞内マグネシウムイオン / TGFα / スーパーオキシド / 羊膜 / 脱落膜 / プロスタグランヂン / 細胞内カルシウム / スーパーオキシト / カルシウム / マグネシウム / pH / superoxide / prostaglandin / calcium / magnesium / TGF-alpha / カルシウム依存性ホルモン分泌 / 細胞骨格 / アクチン / ファロイジン / ファイロジン / Exocytosis / Cytoskeleton / Actin / Phalloidin / 卵巣摘除マウス / Acyl CoA Synthetase / 上皮成長因子 / 分化 / Nothern blot / mutants / menopause / MAP kinase / TiT / GF細胞 / プロラクチン分泌 / TIT / chemokine / 濾胞星状細胞 / 免疫細胞化学 / GF cells / Immunocytochemistry / 細胞浸潤 / 上皮成長因子(EGF) / ケモカイネーシス / 細胞外マトリックス / プロモーター / MAPキナーゼ系 / JAK-STAT系 / 増殖因子 / サイトカイン / integrin / placenta / invasion / epidermal growth factor / chemokinasis / 脂肪細胞 / 転写抑制 / lipid metabolism / adipocyte / estrogen receptor / ES細胞 / trohoblast / BMP4 / ES cell / 羊膜絨毛膜炎 / 早産 / 低分子量Gタンパク / Rho A / Rho-kinase経路 / Y-27632 / chorioamnionitis / preterm delivery / cervical ripening / 血管内皮能 / Brachial artery flow-mediated dilatation / 内皮細胞損傷修復 / 血管内皮機能 / 両側卵巣摘出術 / Survival factor / 血管内皮細胞 / raloxifene / vasodilatation / atherosclerosis / 妊娠中毒症 / 血管攣縮 / 血管内皮障害 / 低分子量G蛋白 / preeclampsia / vasoconstriction / endothelial dysfunction / monomeric G protein / 下垂体前葉細胞 / CTH_3細胞 / プロクラチン / ホスファチジールイノシトール / アラキドン酸 / Cキナーゼ / TRH,LH-RH / PMA / 5-HETE / Prolactin / Pituitary cells / Calcium / GH_3 cells / Protein kinase C / Phosphatidyl inositol Less

Analysis of chemo-resistance genes with promoter micro-array in ovarian cancer
- Principal Investigator
  
  OHMICHI Masahide
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
選択的エストロゲン受容体調節薬の組織特異的な分子制御機構
- Principal Investigator
  
  大道正英
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
  Osaka University
卵巣癌の薬剤耐性化機構の解明と耐性化に関与する分子を標的とする治療法の開発
- Principal Investigator
  
  大道正英
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
絨毛細胞の浸潤能、遊走能制御機構の解明
- Principal Investigator
  
  西尾幸浩
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
A possible role of monomeric GTPase Rho family in the pathogenesis of preeclampsia-New approach to analyse the pathogenesis of preeclampsia-
- Principal Investigator
  
  TAHARA Masahiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
絨毛細胞の分化を制御する転写因子の解析
- Principal Investigator
  
  武田卓
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
FRETを用いたエキソサイトーシス時のリガンド、受容体の細胞内移動の解析Principal Investigator
- Principal Investigator
  
  田坂慶一
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of the interaction between fetal cells and maternal cells in placenta formation using green-mouse embryosPrincipal Investigator
- Principal Investigator
  
  TASAKA Keiichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Trophoblast cells differentiation during placenta development is defined by many transcription factors that act as molecular switches to activate or repress specific gene expressions
- Principal Investigator
  
  SAKATA Masahiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Involvement of RhoA/Rho-kinase pathway in the mechanisms regulating uterine muscle contraction. -Rho-kinase as a possible therapeutic target for prevention of preterm delivery -
- Principal Investigator
  
  TAHARA Masahiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Cardioprotective effect of estrogen and raloxifene
- Principal Investigator
  
  OHMICHI Masahide
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
  Yamagata University
Regulation mechanism of lipid metabolism related gene by estrogen βPrincipal Investigator
- Principal Investigator
  
  TASAKA Keiichi, 山本敏也
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Trophoblast cell invasiveness and the mechanisms of its regulation
- Principal Investigator
  
  KURACHI Hirohisa, 三宅侃
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Molecular mechanism of estrogen action to inhibit obesity
- Principal Investigator
  
  KURACHI Hirohisa
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
胎盤とサイトカイン、成長因子に関する研究
- Principal Investigator
  
  山口正明
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
下垂体細胞顆粒放出における低分子量G蛋白の役割に関する研究Principal Investigator
- Principal Investigator
  
  田坂慶一
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Molecular mechanism of estrogen action to inhibit obesity
- Principal Investigator
  
  KURACHI Hirohisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
The influence of chemokine on hypothalamo-pituitary system
- Principal Investigator
  
  IKEGAMI Hiromasa
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
インターロイキン8の間脳・下垂体・卵巣系に及ぼす影響
- Principal Investigator
  
  小池浩司
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Determination of the target cells of activins and the mechanisms of FSH secretion stimulated by activinsPrincipal Investigator
- Principal Investigator
  
  TASAKA Keiichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
視床下部ドーパミンニューロンの制御機構の解明
- Principal Investigator
  
  IKEGAMI Hiromasa
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Studies on the mechanisms of infection-induced prematuer delivery and its treatment
- Principal Investigator
  
  MIYAKE Akira
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Biochemical Investigation of the Changes of Cytoskeletons during the Exocytosis
- Principal Investigator
  
  NISHIZAKI Takamichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Expression of EGF Receptor and its mRNA in Human Ovarian CancersPrincipal Investigator
- Principal Investigator
  
  KOMURA Hiroko, 田坂慶一
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Molecular mechanism of gonadotropin and prolactin release from pituitary cells
- Principal Investigator
  
  AONO Toshihiro
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokushima
  Osaka University

All 2005 2003

All Journal Article

[Journal Article] Molecular Mechanism of Action of Selective Estrogen Receptor Modulator in Target Tissues2005
- Author(s)
  Ohmichi M, Tasaka K, Kurachi H, Murata Y.
- Journal Title
  
  Endocr.J. 52(2)
  
  Pages: 161-167
- NAID
  10015548851
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571560
[Journal Article] Molecular Mechanism of Action of Selective Estrogen Receptor Modulator in Target Tissues.2005
- Author(s)
  Ohmichi, M., Tasaka, K., Kurachi, H., Murata, Y.
- Journal Title
  
  Endocr J. 52(2)
  
  Pages: 161-167
- NAID
  10015548851
- Data Source
  KAKENHI-PROJECT-17659516
[Journal Article] エストロゲンと血管作用-血管内皮2005
- Author(s)
  大道正英, 早川潤, 佐々木浩, 磯部晶, 田坂慶一, 村田雄二
- Journal Title
  
  Hormone Frontier In Gynecology 12
  
  Pages: 17-21
- Data Source
  KAKENHI-PROJECT-17659516
[Journal Article] Rapid changes of flow-mediated dilatation after surgical Menopause2003
- Author(s)
  Ohmichi M, Kanda Y, Hisamoto K, Morishige K, Takahashi K, Sawada K, Minekawa R, Tasaka K, Murata Y.
- Journal Title
  
  Maturitas 44(2)
  
  Pages: 125-131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571560

1. SAKATA Masahiro (10260639)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. OHMICHI Masahide (10283764)

# of Collaborated Projects: 10 results

# of Collaborated Products: 4 results
3. TAHARA Masahiro (00294091)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
4. KURACHI Hirohisa (40153366)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. TAKEDA Takashi (20301260)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. MIYAKE Akira (90093468)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. MORISHIGE Kenichiro (90283788)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. NISHIO Yukihiro (30303952)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. IKEGAMI Hiromasa (10184409)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. HIROTA Kenji (00189888)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. MINEKAWA Ryoko (10359838)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. TAKAHASHI Kazuhiro (20292427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. TAKEHARA Mikio (40298766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KANEMURA Masanori (40298782)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. HAYAKAWA Jun (80397736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. HASHOMOTO Namiko (60379253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. NISHIZAKI Takamichi (20237689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. KOMURA Hiroko (80195685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 小池浩司 (70225340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 山本敏也 (80283787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 寺川直樹 (90135690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. TERAI Yoshito (90278531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAMASHITA Yoshiki (50268207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANABE Akiko (70454543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SASAKI Hiroshi (80432491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KAMEGAI Hideki (30204639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YOSHIMOTO Yasuhiro (10182833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. AONO Toshihiro (50028445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. AZUMA Keijiro (20192958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. IRAHARA Minoru (20160070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 山口正明 (70273662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 中原健次 (80250934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 楢原敬二郎 (60368074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 奥田喜代司 (90131325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 吉田雅人 (20312738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 堤博久 (40135710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TASAKA Keiichi 田坂 慶一

田坂 慶一 タサカ ケイイチ

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FRETを用いたエキソサイトーシス時のリガンド、受容体の細胞内移動の解析Principal Investigator

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Analysis of the interaction between fetal cells and maternal cells in placenta formation using green-mouse embryosPrincipal Investigator

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Regulation mechanism of lipid metabolism related gene by estrogen βPrincipal Investigator

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TASAKA Keiichi 田坂慶一

田坂慶一タサカケイイチ