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NAKAHARA Kenji
中原 健次
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Alternative Names
中原 健次 ナカハラ ケンジ
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Researcher Number
80250934
Affiliation (based on the past Project Information)
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2007: Yamagata University, Faculty of Medicine, Associate Professor
1999 – 2006: Dep Ob-Gyn, School of Medicine, Yamagata University, Assist. Professor, 医学部, 講師
2004: 国立大学法人山形大学, 医学部, 講師
1996 – 1998: Yamagata Univ.OB/GYN Assistant, 医学部, 助手
1994: 山形大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
/
Obstetrics and gynecology
/
Biological Sciences
Keywords
Principal Investigator
顆粒膜細胞 / 卵巣 / アポトーシス / 卵胞閉鎖 / APOPTOSIS / OVARY / ATRESIA OF FOLLICLE / GRANULOSA CELL / INTRACELLULAR SIGNAL TRANSDUCTION / Steroidgenesis
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/ NO / growth hormone / 卵胞発育 / マクロファージ / マウス / 細胞内シグナル伝達 / 卵の質 / シグナル伝達 / 卵胞
…
More
Except Principal Investigator
エストロゲン受容体 / エストロゲン / 上皮成長因子(EGF) / 転写制御 / 卵胞 / CD44 / MAPキナーゼ / 細胞周期 / テロメラーゼ / アポトーシス / cyclin D1 / シスプラチン耐性 / タキソール耐性 / マウス卵巣癌モデル / シグナル伝達関連因子 / アポトーシス関連因子 / ERK経路 / Akt経路 / BAD / インスリン様増殖因子(IGF)-1 / 欠失変異 / シグナル伝達 / 核内分布 / GFPキメラ蛋白 / 変異遺伝子 / AF-2ドメイン / 蛍光顕微鏡 / 共焦点レーザー顕微鏡 / 受精 / 胚発育 / 卵管特異糖蛋白 / カルシウム オスシレーション / 顕微受精 / カルシウムオスシレーション / 顕微授精 / 透明帯 / 卵管分泌性糖蛋白 / 卵の糖代謝 / steroidogenesis / 細胞内カルシウム / アポト-ジス / 卵子 / 精子 / 卵管因子 / 子宮筋gap junction / fertilization / embryo / oviduct glycoprotein / Ca-oscillation / microinsemination / 顆粒膜細胞 / steroid産生 / アポトージス / 卵透明帯 / Ovarian follicle / Granulosa Cell / Steroidogenesis / Apoptosis / 繊毛細胞 / 接着因子 / 浸潤能 / 遊走能 / インテグリン / 絨毛細胞 / 細胞接着因子 / 上皮成長因子 (EGF) / 細胞浸潤能 / ケモタキシス / 細胞浸潤 / 転写因子 / trophoblast / adhesion molecule / invasion / chemokinesis / integrin / epidermal growth factor (EGF) / gene transcription / 卵の質 / 酸化ストレス / 8-OHdG / グルタチオンリダクターゼ / 卵 / 胚 / 凍結 / ヒアルロン酸 / quality of oocyte / oxidative stress / cell cycle / 8 OhdG / glutathione reductase / 動脈硬化 / リン酸化 / MAPキナーゼ経路 / 選択的エストロゲン受容体修飾薬 / 乳がん / ラロキシフェン / 血管平滑筋 / PI3K / Akt / NFκB経路 / nongenomicな作用 / 増殖 / サイクリンD1 / Rb蛋白 / プロモーター / p38経路 / 細胞内情報伝達 / estrogen receptor / atherosclerosis / apoptosis / phosphorylation / MAP kinase pathway / selective estrogen receptor modulator / mammary carcinoma / 卵巣癌 / 分子標的治療 / EGF受容体 / シグナル伝達経路 / 抗癌剤 / EGF受容体(EGFR) / DNA損傷 / ovanan cancer / molecular tareeted therapy / EGF receptor / sienal transduction / anti cancer drug
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Research Projects
(
12
results)
Research Products
(
2
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Study for the development of molecular therapy targeting the signal transduction pathway through epidermal growth factor receptor
Principal Investigator
KURACHI Hirohisa
Project Period (FY)
2005 – 2007
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
卵巣癌の薬剤耐性化機構の解明と耐性化に関与する分子を標的とする治療法の開発
Principal Investigator
OUMICHI Masahide
Project Period (FY)
2004
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Osaka University
リガンド依存性・非依存性のエストロゲン受容体活性化と核内分布変化を可視化する試み
Principal Investigator
倉智 博久
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
Antiatherogenic action of estrogen through inhibition of pathological proliferation in vascular smooth muscle sells
Principal Investigator
KURACHI Hirohisa
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
EVALUATION OF OOCYTES QUALITY THOROUGH ANALYSIS OF APOPTOTIC SIGNAL TRANSDUCTION IN FOLLICLES.
Principal Investigator
Principal Investigator
NAKAHARA Kenji
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
YAMAGATA UNIVERSITY
Study of factors regulating the development of follicles, oocytes and embryos
Principal Investigator
SAITO Hidekazu
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
ELUCIDATION OF MAKING ATRETIC FOLLICLES VIA APOPTOSIS AND MECHANISM OF INTRACELLULAR APOPTOTIC SIGNALS
Principal Investigator
Principal Investigator
NAKAHARA Kenji
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
YAMAGATA UNIVERSITY
Differentiation- dependent regulation of adhesion molecules in trophoblast cells
Principal Investigator
KURACHI Hirohisa
,
西尾 幸浩
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
Osaka University
Studies on the regulatory mechanism of interaction between the development of ovulatry follicle and ovum in the ovary.
Principal Investigator
HIROI Masahiko
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
YAMAGATA UNIVERSITY
卵胞発育・閉鎖機構における免疫機序および黄体退縮機序の解明
Principal Investigator
Principal Investigator
中原 健次
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
亜鉛及び銅イオン動態がステロイドホルモン・レセプター動態に及ぼす影響
Principal Investigator
Principal Investigator
中原 健次
Project Period (FY)
1994
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
Mechanism of fertilization and embryo development
Principal Investigator
HIROI Masahiko
Project Period (FY)
1993 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Obstetrics and gynecology
Research Institution
Yamagata University
All
2006
All
Journal Article
[Journal Article] Clinical outcome and risk factors for recurrence in borderline ovarian tumours.
2006
Author(s)
Yokoyama Y, Moriya T, Takano T, Shoji T, Takahasi O, Nakahara K, Yamada H, Yaegashi N, Okamura K, Izutsu T, Sugiyama T, Tanaka T, Kurachi H, Sato A, Tase T, Mizunuma H.
Journal Title
Br J Cancer 94(11)
Pages
: 1586-1591
Data Source
KAKENHI-PROJECT-17390445
[Journal Article] Usefulness of intraovarian artery pulsatility and resistance indices measurement on the day of follicle aspiration for the assessment of oocyte quality.
2006
Author(s)
Du B, Takahashi K, Ishida GM, Nakahara K, Saito H, Kurachi H.
Journal Title
Fertil Steril 85(2)
Pages
: 366-370
Data Source
KAKENHI-PROJECT-17390445
# of Projects (Dsc)
# of Projects (Asc)
1.
KURACHI Hirohisa
(40153366)
# of Collaborated Projects:
7 results
# of Collaborated Products:
2 results
2.
SAITO Hidekazu
(90125766)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
TAKAHASHI Kazuhiro
(20292427)
# of Collaborated Projects:
4 results
# of Collaborated Products:
1 results
4.
SAITO Takakazu
(00272071)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
OUMICHI Masahide
(10283764)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
TANAKA Eiichi
(20322000)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
HIROI Masahiko
(60018364)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
SAKATA Masahiro
(10260639)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
TEZUKA Naohiro
(60261690)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
TAKAHASHI Toshifumi
(20302292)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
KAWACHIYA Satoshi
(30322001)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
ARAKI Yoshihiko
(70250933)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
HIRAYAMA Toshio
(60238392)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
ITOH Mariko
(40292429)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
YAMAMOTO Toshiya
(80283787)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
MORISHIGE Kenichirou
(90283788)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
TUTUMI Seiji
(50323168)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
ABE Akiko
(30359567)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
HAYASAKA Tadashi
(10375339)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
田坂 慶一
(50155058)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
五十嵐 秀樹
(80333970)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
小宮 雄一
(70234888)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
川越 慎之助
(10018880)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
太田 信彦
(40301072)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
西尾 幸浩
(30303952)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
清野 朝史
(00311580)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
吉田 雅人
(20312738)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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