TAKEUCHI Tsutomu 竹内勤

Researcher Number	50179610
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022: 慶應義塾大学, 医学部(信濃町), 特任教授 2021 – 2022: 慶應義塾大学, 医学部(信濃町), 名誉教授 2017 – 2020: 慶應義塾大学, 医学部(信濃町), 教授 2009 – 2016: Keio University, 医学部, 教授 1997 – 2009: SAITAMA MEDICAL SCHOOL,SCHOOL OF MEDICINE,PROFESSOR, 医学部, 教授 … More 2002: 埼玉医科大学, 総合医療センター, 教授 1992 – 1997: Saitama Medical Center 2nd Department of Medicine Associate Professor, 医学部, 助教授 1991: 埼玉医科大学, 医学部, 教授 1991: 埼玉医科大学, 医学部, 講師 1989: Saitama Medical Center 2nd Dep. Int. Med. Assistant Professor, 総合医療センター第2内科, 講師 1989: 埼玉医科大学, 総合医療センター・第2内科, 講師 1988: 助手 Less
Review Section/Research Field	Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology / Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology
Keywords	Principal Investigator SLE / autoimmunity / LFA-1 / VLA-4 / シグナル伝達 / インテグリン / 自己免疫 / Integrins / 関節リウマチ / CD103 … More / 自己免疫疾患 / 自己抗体 / TCRζ chain / BAFF / シェーグレン症候群 / apoptosis / adhesion / epithelial cells / pp125FAK / チロシンリン酸化 / Signal transduction / Vasculitis / 血管炎 / 血管内皮細胞 / リンパ球 / FAM20A / カドヘリン / 上皮障害 / 残存分子シグネチャー / 診断前継時コホート / 寛解、分子病態、網羅的解析 / リウマチ因子 / 肺胞洗浄液 / 抗翻訳後修飾蛋白抗体 / 抗シトルリン化タンパク質抗体 / 抗原特異性 / 間質性肺炎 / シングルセル解析 / レパトア解析 / 全身性強皮症 / 自己抗原 / 抗セントロメア抗体 / B細胞 / integrin / adherin / epithelial injuries / microarray / splicing variants / autoantibody / 3'untranslated region / splicing / 3' untranslated region / T lymphocytes / tyrosine phosphorylation / CD3 zeta chain / lupus / T cell receptor / signaal transduction / T細胞リセプター / TCRζ鎖 / E-cadherin / シェ-グレン症候群 / アポトーシス / 組織障害 / E-カドヘリン / E-cadherins / Tyrosine phosphorylation / p125FAK / Endothelial cells / Fibronectin / 接着分子 / フィブロネクチン / HUVEC / Lymphocytes / LFAー1 / VLAー4 / リウマチ内科学 / 膠原病・アレルギー内科学 / 分泌型キナーゼ / キナーゼ / PTPN1 / JMJD1A / 機能解析 / 末梢血 / 14-3-3zeta / 発現異常 / mRNA / 病態形成 / 網羅的遺伝子解析 / 遺伝子発現 / DNAマイクロアレイ / CDIO3 … More Except Principal Investigator alternative splicing / signal transduction / mRNA 3'UTR / 慢性関節リウマチ / 全身性エリテマトーデス / syndecan / EXTL2 / Systemic lupus erythematosus / mRNA3'UTR / MA5.8 / TCRζ鎖 / VCAM-1 / VLA / rheumatoid arthritis / 関節リウマチ / シグナル伝達 / 単球 / T細胞 / フローサイトメトリー / ノックアウトマウス / 末梢血 / MS4A4A / anti-idiotypic antibody / bacterial infection / rheumatoid factor / 微生物 / プロテインA / 関節症状 / Fc結合蛋白 / 抗イデイオタイプ抗体 / 肺炎球菌 / リウマトイド因子 / TCR ζ / exon deletion / syndecan-1 / cDNA microarray / ヘパラン硫酸 / signla transduction / シンデカン / Syndecan / TCRζ / 半定量PCR法 / dimerization / In vitro translation / apoptosis / lymphocytes / systemic lupus erythematosus (SLE) / c-Jun N-terminal kinase-1 (JNK-1) / Ultraviolet / 光線過敏症 / アポトーシス / リンパ球 / SLE / JNK-1 / 紫外線 / Synovium / Fibronectin / Rheumatoid Arthritis / 活性化 / チロシンリン酸化 / 形態変化 / 滑膜細胞フィブロネクチン / フイブロネクチン / 滑膜 / フィブロネクチン / CD44 antigen / zata chain / PDGF / T cell phosphorylation / 燐酸化 / CD3分子 / 血小板由来増殖因子 / 線維芽様細胞 / CD44抗原 / 抗DR抗体 / 破骨活性 / 多核巨細胞 / 滑膜細胞 / 関節エコー / 低侵襲検査 / 滑膜生検 / 低侵襲検査法 / 臨床研究 / 滑膜組織 / BAFF受容体 / リン酸化 / 阻害剤 / JAK3 / IL-6 / 細胞シグナル伝達 / BAFF / シェーグレン症候群 / サイトカイン / 膠原病学 / 免疫寛容 / アイソフォーム / アイソフォーム免疫寛容 / FOXP3 / 制御性T細胞 / 関節炎 / 発熱 / データベース / アンケート / 成人発症スティル病 Less

Molecular signatures in pre-RA patients by multi-omics analysisPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Keio University
Function and clinical application of MS4A4A involved in pathology of rheumatoid arthritis
- Principal Investigator
  
  Yamaoka Kunihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
Multiomics analysis of auto reactive immune cells in the inflammatory sites in autoimmune diseases.Principal Investigator
- Principal Investigator
  
  Takeuchi Tsutomu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Keio University
Investigation of regulatory mechanism of secretary protein kinase and its application for treatment of rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Takeuchi Tsutomu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Keio University
Clinical studies on the development of new minimum invasive diagnostic test for rheumatoid arthritis
- Principal Investigator
  
  Suzuki Katsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Keio University
Identification and characterization of pathogenesis related molecules in early rheumatoid arthritis by DNA microarrayPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Search for BAFF signaling inhibitors as novel drugs for the treatment of Sjogren's syndrome.
- Principal Investigator
  
  YOSHIMOTO Keiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Analysis on signal transduction pathway through CD103 moleculePrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saitama Medical University
FOXP3 isoform expression in the regulatory T cells in systemic lupus erythematosus patients and its role in the mechanism of the immue suppression
- Principal Investigator
  
  SUZUKI Katsuya
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saitama Medical University
Molecular mechanism and its regulation of heterophilic adhesion between α E 3 7 (CD103) and E-cadherin in autoimmune epithelial injuryPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saitama Medical University
Decreased expression of TCRζ and signal transduction due to the aberrantexpression of the TCR mRNA in SLE patient T cells
- Principal Investigator
  
  TSUZAKA Kensei
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saitama Medical University
成人発症スティル病の診断・治療・予後に関する集学的研究
- Principal Investigator
  
  江口勝美
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Nagasaki University
Molecular mechanism and possible therapeutic target of BAFF upregulation in SLEPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
Analysis of the aberrant TCRζ mRNA 3'UTR in SLE patient T cells
- Principal Investigator
  
  TSUZAKA Kensei
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
全身性エリテマトーデス患者T細胞に発現されるTCRζ鎖の異常に関する研究Principal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
Role of alphaEbeta7 on tissue destruction of autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
PATHOGENETIC SIGNIFICANCE OF PROTEIN KINASE JNK-1 INDUCED BY ULTRAVIOLET IN PERIPHERAL BLOOD LYMPHOCYTES FROM SLE PATIENTS
- Principal Investigator
  
  AMANO Koichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  SAITAMA MEDICAL SCHOOL
Study on signal transduction pathway via integrins in autoimmune T cellsPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
Structure of upregulated VLA-4 antigen expressed on PBL from SLEPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
The role of VLA proteins and fibronectin in the activation of synovial cells from rheumatoid arthritis.
- Principal Investigator
  
  MATSUYAMA Takami
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kagoshima University
  Saitama Medical University
Studies on the pathogenesis of rheumatoid arthritis
- Principal Investigator
  
  ABE Tohru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical Center, Saitama Medical School
Molecular immunological study on the pathogenesis of vasculitis in SLEPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tsutomu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical School
Studies on the mechanism of rheumatoid factor production
- Principal Investigator
  
  ABE Tohru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical Center, Saitama Medical School

[Journal Article] Distinct gene signatures of monocytes and B cells in patients with giant cell arteritis: a longitudinal transcriptome analysis2023
- Author(s)
  Kotaro Matsumoto, Katsuya Suzuki, Hiroto Yoshida, Mayu Magi, Yoshihiro Matsumoto, Mariko Noguchi-Sasaki, Keiko Yoshimoto, Tsutomu Takeuchi, Yuko Kaneko
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 25 Issue: 1 Pages: 1-1
- DOI
  10.1186/s13075-022-02982-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08527, KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K16306
[Journal Article] Longitudinal monitoring of circulating immune cell phenotypes in anti-neutrophil cytoplasmic antibody-associated vasculitis2023
- Author(s)
  Matsumoto Kotaro、Suzuki Katsuya、Yasuoka Hidekata、Hirahashi Junichi、Yoshida Hiroto、Magi Mayu、Noguchi-Sasaki Mariko、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: 22 Issue: 3 Pages: 103271-103271
- DOI
  10.1016/j.autrev.2023.103271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K16306
[Journal Article] Reduced versus maximum tolerated methotrexate dose concomitant with adalimumab in patients with rheumatoid arthritis (MIRACLE): a randomised, open-label, non-inferiority trial2023
- Author(s)
  Tamai Hiroya、Tsutomu Takeuchi et al.
- Journal Title
  
  The Lancet Rheumatology
  
  Volume: 5 Issue: 4 Pages: e215-e224
- DOI
  10.1016/s2665-9913(23)00070-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-22K08527
[Journal Article] Successful treatment of IgG4-related disease with tocilizumab monotherapy2023
- Author(s)
  Akiyama Mitsuhiro、Hayashi Yutaro、Suzuki Koji、Takeuchi Tsutomu、Kaneko Yuko
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: 22 Issue: 4 Pages: 103296-103296
- DOI
  10.1016/j.autrev.2023.103296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and pharmacokinetics of ozoralizumab, an anti-TNFα NANOBODY compound, in patients with rheumatoid arthritis: 52-week results from the OHZORA and NATSUZORA trials2023
- Author(s)
  Takeuchi Tsutomu、Chino Yukihiro、Kawanishi Masafumi、Nakanishi Megumi、Watase Hirotaka、Mano Yoko、Sato Yuri、Uchida Saeko、Tanaka Yoshiya
- Journal Title
  
  Arthritis Research and Therapy
  
  Volume: 25 Issue: 1
- DOI
  10.1186/s13075-023-03036-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and tolerability of subcutaneously administered methotrexate including dose escalation in long-term treatment of rheumatoid arthritis in a Japanese population2022
- Author(s)
  Tanaka Yoshiya、Okuda Kosuke、Takeuchi Yohei、Katayama Kou、Haji Yoichiro、Yamanishi Yuji、Tribanek Michael、Guimbal-Schmolck Cecile、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 4 Pages: 680-689
- DOI
  10.1093/mr/roac103
- Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and safety of the anti-TNF multivalent NANOBODY compound ozoralizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: A 52-week result of a Phase II/III study (OHZORA trial)2022
- Author(s)
  Tanaka Yoshiya、Kawanishi Masafumi、Nakanishi Megumi、Yamasaki Hironori、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 5 Pages: 883-890
- DOI
  10.1093/mr/roac119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Immune evasion and chronological decrease in titer of neutralizing antibody against SARS-CoV-2 and its variants of concerns in COVID-19 patients2022
- Author(s)
  Takeshita Masaru、Nishina Naoshi、Moriyama Saya、Takahashi Yoshimasa、Ishii Makoto、Saya Hideyuki、Kondo Yasushi、Kaneko Yuko、Suzuki Katsuya、Fukunaga Koichi、Takeuchi Tsutomu
- Journal Title
  
  Clinical Immunology
  
  Volume: 238 Pages: 108999-108999
- DOI
  10.1016/j.clim.2022.108999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17450, KAKENHI-PROJECT-20H03720
[Journal Article] Nation-wide cohort study of remission induction therapy using rituximab in Japanese patients with antineutrophil cytoplasmic antibody associated vasculitis: Effectiveness and safety in the first 6 months2022
- Author(s)
  Nagasaka Kenji、Amano Koichi、Dobashi Hiroaki、Nagafuchi Hiroko、Sada Ken-Ei、Komagata Yoshinori、Yamamura Masahiro、Kato Masaru、Endo Tomomi、Nakaya Izaya、Takeuchi Tsutomu、et al.
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 6 Pages: 1117-1124
- DOI
  10.1093/mr/roac150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results2022
- Author(s)
  Tanaka Yoshiya、Matsubara Tsukasa、Tsutomu Takeuchi, et al.
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 4 Pages: 668-679
- DOI
  10.1093/mr/roac084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
[Journal Article] Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis2022
- Author(s)
  Kerschbaumer Andreas、Sepriano Alexandre、Bergstra Sytske Anne、Smolen Josef S、van der Heijde D、Caporali Roberto、Edwards Christopher John、Verschueren Patrick、de Souza Savia、Pope Janet E、Takeuchi Tsutomu、Hyrich Kimme L、Winthrop Kevin L、Aletaha Daniel、Stamm Tanja A、Schoones Jan W、Landew Robert B M
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Issue: 1 Pages: 95-106
- DOI
  10.1136/ard-2022-223365
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years2022
- Author(s)
  Ishiguro Naoki、Tanaka Yoshiya、Matsubara Tsukasa、Atsumi Tatsuya、Amano Koichi、Sugiyama Eiji、Yamaoka Kunihiro、Winthrop Kevin、Kivitz Alan、Burmester Gerd R、Gottenberg Jacques-Eric、Genovese Mark C、Matzkies Franziska、Guo Ying、Jiang Deyuan、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 33 Issue: 1 Pages: 64-72
- DOI
  10.1093/mr/roac020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
[Journal Article] Long-term safety and effectiveness of mycophenolate mofetil in adults with lupus nephritis: a real-world study in Japan2022
- Author(s)
  Takeuchi Tsutomu、Hashimoto Hideyuki、Matsumoto Mika
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 4 Pages: 746-754
- DOI
  10.1093/mr/roab076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 1)2022
- Author(s)
  Tanaka Yoshiya、Matsubara Tsukasa、Atsumi Tatsuya、Amano Koichi、Ishiguro Naoki、Sugiyama Eiji、Yamaoka Kunihiro、Sundy John S、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 2 Pages: 263-272
- DOI
  10.1093/mr/roab030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Impact of age on the efficacy and safety of peficitinib (ASP015K) for the treatment of rheumatoid arthritis2022
- Author(s)
  Tanaka Yoshiya、Takeuchi Tsutomu、Kato Daisuke、Kaneko Yuichiro、Fukuda Musashi、Miyatake Daisuke
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 4 Pages: 696-707
- DOI
  10.1093/mr/roab058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Longitudinal monitoring of circulating immune cell phenotypes in large vessel vasculitis2022
- Author(s)
  Matsumoto Kotaro、Suzuki Katsuya、Yoshida Hiroto、Magi Mayu、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: 21 Issue: 10 Pages: 103160-103160
- DOI
  10.1016/j.autrev.2022.103160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K16306
[Journal Article] Correction: Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases RA as a role model2022
- Author(s)
  Takeuchi Tsutomu
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1
- DOI
  10.1186/s41232-022-00250-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Safety and effectiveness of baricitinib for rheumatoid arthritis in Japanese clinical practice: 24-week results of all-case post-marketing surveillance2022
- Author(s)
  Takagi Michiaki、Atsumi Tatsuya、Matsuno Hiroaki、Tamura Naoto、Fujii Takao、Okamoto Nami、Takahashi Nobunori、Nakajima Atsuo、Nakajima Ayako、Tsujimoto Naoto、Nishikawa Atsushi、Ishii Taeko、Takeuchi Tsutomu、Kuwana Masataka
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 4 Pages: 647-656
- DOI
  10.1093/mr/roac089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update2022
- Author(s)
  Smolen Josef S、Landew Robert B M、、Tsutomu Takeuchi, et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Issue: 1 Pages: 3-18
- DOI
  10.1136/ard-2022-223356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] A systematic literature review informing the consensus statement on efficacy and safety of pharmacological treatment with interleukin-6 pathway inhibition with biological DMARDs in immune-mediated inflammatory diseases2022
- Author(s)
  Kastrati Kastriot、Aletaha Daniel、Burmester Gerd R、Chwala Eva、Dejaco Christian、Dougados Maxime、McInnes Iain B、Ravelli Angelo、Sattar Naveed、Stamm Tanja A、Takeuchi Tsutomu、Trauner Michael、van der Heijde D、Voshaar Marieke J H、Winthrop Kevin、Smolen Josef S、Kerschbaumer Andreas
- Journal Title
  
  RMD Open
  
  Volume: 8 Issue: 2 Pages: e002359-e002359
- DOI
  10.1136/rmdopen-2022-002359
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] ‘Not at target’: prevalence and consequences of inadequate disease control in systemic lupus erythematosus-A multinational observational cohort study2022
- Author(s)
  Kandane-Rathnayake Rangi、Louthrenoo Worawit、Hoi AlbertaKatsumata Yasuhiro、Harigai MasayoKikuchi Jun、Takeuchi TsutomuFor the Asia-Pacific Lupus Collaboration
- Journal Title
  
  Arthritis Research and Therapy
  
  Volume: 24 Issue: 1
- DOI
  10.1186/s13075-022-02756-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Safety of baricitinib for the treatment of rheumatoid arthritis over a median of 4.6 and up to 9.3 years of treatment: final results from long-term extension study and integrated database2022
- Author(s)
  Taylor Peter C、Takeuchi Tsutomu、Burmester Gerd R、Durez Patrick、Smolen Josef S、Deberdt Walter、Issa Maher、Terres Jorge Ross、Bello Natalia、Winthrop Kevin L
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 3 Pages: 335-343
- DOI
  10.1136/annrheumdis-2021-221276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Lupus low disease activity state within 12 months is associated with favourable outcomes in severely active systemic lupus erythematosus2022
- Author(s)
  Kikuchi Jun、Hanaoka Hironari、Saito Shuntaro、Oshige Tatsuhiro、Hiramoto Kazuoto、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 9 Pages: 3777-3791
- DOI
  10.1093/rheumatology/keac002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08889, KAKENHI-PROJECT-19K17892, KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and safety of filgotinib alone and in combination with methotrexate in Japanese patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 3)2022
- Author(s)
  Atsumi Tatsuya、Tanaka Yoshiya、Matsubara Tsukasa、Amano Koichi、Ishiguro Naoki、Sugiyama Eiji、Yamaoka Kunihiro、Westhovens Ren、Ching Daniel W.T、Messina Osvaldo Daniel、Burmester Gerd R、Bartok Beatrix、Pechonkina Alena、Kondo Akira、Yin Zhaoyu、Guo Ying、Tasset Chantal、Sundy John S、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 2 Pages: 273-283
- DOI
  10.1093/mr/roab021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy, duration of use and safety of glucocorticoids: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis2022
- Author(s)
  Bergstra Sytske Anne、Sepriano Alexandre、Kerschbaumer Andreas、van der Heijde D、Caporali Roberto、Edwards Christopher John、Verschueren Patrick、de Souza Savia、Pope Janet E、Takeuchi Tsutomu、Hyrich Kimme L、Winthrop Kevin L、Aletaha Daniel、Stamm Tanja A、Schoones Jan W、Smolen Josef S、Landew Robert B M
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Issue: 1 Pages: 81-94
- DOI
  10.1136/ard-2022-223358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Thymus variants on imaging of patients with primary Sjogren’s syndrome and polymyositis/dermatomyositis: clinical and immunological significance2022
- Author(s)
  Murata Okinori、Suzuki Katsuya、Takeuchi Tsutomu
- Journal Title
  
  Immunological Medicine
  
  Volume: 46 Issue: 1 Pages: 25-31
- DOI
  10.1080/25785826.2022.2129371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Efficacy and safety of abatacept in biologic-naive patients with active rheumatoid arthritis by background methotrexate dose: <i>post hoc</i> analysis of a randomized, placebo-controlled, phase 4 study2022
- Author(s)
  Tanaka Yoshiya、Matsubara Tsukasa、Hashizume Koichi、Amano Norihito、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 3 Pages: 500-507
- DOI
  10.1093/mr/roab029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study2022
- Author(s)
  Kandane-Rathnayake Rangi、Golder Vera、Tsutomu Takeuchi, et al.
- Journal Title
  
  The Lancet Rheumatology
  
  Volume: 4 Issue: 12 Pages: e822-e830
- DOI
  10.1016/s2665-9913(22)00304-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years2022
- Author(s)
  Winthrop Kevin L、Tanaka Yoshiya、Takeuchi Tsutomu、Kivitz Alan、Matzkies Franziska、Genovese Mark C、Jiang Deyuan、Chen Kun、Bartok Beatrix、Jahreis Angelika、Besuyen Robin、Burmester Gerd R、Gottenberg Jacques-Eric
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 2 Pages: 184-192
- DOI
  10.1136/annrheumdis-2021-221051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Benefit of Filgotinib, a JAK1 Preferential Inhibitor, in Rheumatoid Arthritis Patients with Previous Rapid Radiographic Progression: Post Hoc Analysis of Two Trials2022
- Author(s)
  Tanaka Yoshiya、Atsumi Tatsuya、Aletaha Daniel、Bartok Beatrix、Pechonkina Alena、Han Ling、Emoto Kahaku、Kano Shungo、Rajendran Vijay、Takeuchi Tsutomu
- Journal Title
  
  Rheumatology and Therapy
  
  Volume: NA
- DOI
  10.1007/s40744-022-00503-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Rheumatoid arthritis with nontuberculous mycobacterial pulmonary disease: a retrospective, single-centre cohort study2022
- Author(s)
  Takei Hiroshi、Nishina Naoshi、Namkoong Ho、Suzuki Katsuya、Uwamino Yoshifumi、Hasegawa Naoki、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 3 Pages: 534-540
- DOI
  10.1093/mr/roab032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] The efficacy and safety of anifrolumab in Japanese patients with systemic lupus erythematosus: TULIP-2 subanalysis2022
- Author(s)
  Tanaka Yoshiya、Atsumi Tatsuya、Okada Masato、Miyamura Tomoya、Ishii Tomonori、Nishiyama Susumu、Matsumura Ryutaro、Hayashi Nobuya、Abreu Gabriel、Tummala Raj、Morand Eric F、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 33 Issue: 1 Pages: 134-144
- DOI
  10.1093/mr/roac010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Disease-specific expansion of CD29+IL-17RA+ T effector cells possessing multiple signalling pathways in spondyloarthritis2022
- Author(s)
  Akiyama Mitsuhiro、Yoshimoto Keiko、Ishigaki Sho、Suzuki Katsuya、Takeuchi Tsutomu、Kaneko Yuko
- Journal Title
  
  Rheumatology
  
  Volume: 62 Issue: 3 Pages: 1296-1305
- DOI
  10.1093/rheumatology/keac391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16292, KAKENHI-PROJECT-20H03720
[Journal Article] Real-world safety and efficacy of CT-P13, an infliximab biosimilar, in Japanese rheumatoid arthritis patients naive to or switched from biologics2022
- Author(s)
  Takeuchi Tsutomu、Nishikawa Kiyohiro、Yamada Fumika、Ohshima Shiro、Inoue Makoto、Yoshioka Yutaka、Yamanaka Hisashi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 4 Pages: 718-727
- DOI
  10.1093/mr/roab068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Association between the patterns of large-vessel lesions and treatment outcomes in patients with large-vessel giant cell arteritis2022
- Author(s)
  Sugihara Takahiko、Uchida Haruhito A、Yoshifuji Hajime、Maejima Yasuhiro、Naniwa Taio、Katsumata Yasuhiro、Okazaki Takahiro、Ishizaki Jun、Murakawa Yohko、Ogawa Noriyoshi、Dobashi Hiroaki、Horita Tetsuya、Tanaka Yoshiya、Furuta Shunsuke、Takeuchi Tsutomu、Komagata Yoshinori、Nakaoka Yoshikazu、Harigai Masayoshi
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 6 Pages: 1145-1153
- DOI
  10.1093/mr/roac122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With <scp>Long‐Term</scp> Clinical Outcomes: A <scp>Five‐Year</scp> Prospective Study2022
- Author(s)
  Connelly Kathryn、Kandane‐Rathnayake Rangi、Tsutomu Takeuchi, et al.
- Journal Title
  
  Arthritis and Rheumatology
  
  Volume: 75 Issue: 3 Pages: 401-410
- DOI
  10.1002/art.42350
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Safety of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis2022
- Author(s)
  Sepriano Alexandre、Kerschbaumer Andreas、Bergstra Sytske Anne、Smolen Josef S、van der Heijde D、Caporali Roberto、Edwards Christopher J、Verschueren Patrick、de Souza Savia、Pope Janet、Takeuchi Tsutomu、Hyrich Kimme、Winthrop Kevin L、Aletaha Daniel、Stamm Tanja、Schoones Jan W、Landew Robert B M
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Issue: 1 Pages: 107-118
- DOI
  10.1136/ard-2022-223357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] A pooled analysis of serious infections and herpes zoster-related disease in Asian patients with rheumatoid arthritis treated with peficitinib (ASP015K) over a median of 3 years2022
- Author(s)
  Tanaka Yoshiya、Takeuchi Tsutomu、Kato Daisuke、Kaneko Yuichiro、Fukuda Musashi、Izutsu Hiroyuki、Rokuda Mitsuhiro
- Journal Title
  
  Modern Rheumatology
  
  Volume: 32 Issue: 4 Pages: 708-717
- DOI
  10.1093/mr/roab069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] T follicular helper cells mediate local production of allergen-specific IgE and IgG42022
- Author(s)
  Akiyama Mitsuhiro、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 150 Issue: 5 Pages: 1045-1047
- DOI
  10.1016/j.jaci.2022.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16292, KAKENHI-PROJECT-20H03720
[Journal Article] Differences in the strength of inhibition of interleukin-6 signalling by subcutaneous sarilumab and tocilizumab in rheumatoid arthritis patients2022
- Author(s)
  Saito Shuntaro、Suzuki Katsuya、Yoshimoto Keiko、Kondo Yasushi、Kikuchi Jun、Hanaoka Hironari、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: ー Pages: 1451-1455
- DOI
  10.55563/clinexprheumatol/k0ctlf
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-22K08527
[Journal Article] Relative Impact of Pain and Disease Activity on Improvements in Fatigue2022
- Author(s)
  Fautrel Bruno、Wu Jianmin、Wang Duzhe、Haladyj Ewa、van de Laar Mart A. F. J.、Takeuchi Tsutomu
- Journal Title
  
  JCR: Journal of Clinical Rheumatology
  
  Volume: 29 Pages: 139-144
- DOI
  10.1097/rhu.0000000000001924
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] <i>Post hoc</i> analysis of clinical characteristics of patients with radiographic progression in a Japanese phase 3 trial of peficitinib and methotrexate treatment (RAJ4)2022
- Author(s)
  Tanaka Yoshiya、Takeuchi Tsutomu、Kato Daisuke、Kaneko Yuichiro、Fukuda Musashi、Izutsu Hiroyuki、Rokuda Mitsuhiro、van der Heijde D
- Journal Title
  
  Modern Rheumatology
  
  Volume: 33 Issue: 1 Pages: 73-80
- DOI
  10.1093/mr/roac021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update2022
- Author(s)
  Aletaha Daniel、Kerschbaumer Andreas、Tsutomu Takeuchi, et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: ー Issue: 6 Pages: 773-787
- DOI
  10.1136/ard-2022-222784
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Selection of treatment regimens based on shared decision-making in patients with rheumatoid arthritis on remission in the FREE-J study2022
- Author(s)
  Tanaka Yoshiya、Yamaguchi Ayako、Miyamoto Toshiaki、Tanimura Kazuhide、Iwai Hideyuki、Kaneko Yuko、Takeuchi Tsutomu、Amano Koichi、Iwamoto Naoki、Kawakami Atsushi、Murakami Miho、Nishimoto Norihiro、Atsumi Tatsuya、Sumida Takayuki、Ohmura Koichiro et al.
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 11 Pages: 4273-4285
- DOI
  10.1093/rheumatology/keac075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-20H03720
[Journal Article] Long-term safety and efficacy of filgotinib treatment for rheumatoid arthritis in Japanese patients naive to MTX treatment (FINCH 3)2022
- Author(s)
  Atsumi Tatsuya、Tanaka Yoshiya、Matsubara Tsukasa、Amano Koichi、Ishiguro Naoki、Sugiyama Eiji、Yamaoka Kunihiro、Westhovens Ren、Ching Daniel W T、Messina Osvaldo Daniel、Burmester Gerd R、Genovese Mark、Bartok Beatrix、Pechonkina Alena、Kondo Akira、Yin Zhaoyu、Gong Qi、Tasset Chantal、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 4 Pages: 657-667
- DOI
  10.1093/mr/roac083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
[Journal Article] Interleukin-4 as an emerging therapeutic target for IgG4-related disease2022
- Author(s)
  Akiyama Mitsuhiro、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 2 Pages: e28-e28
- DOI
  10.1136/annrheumdis-2020-216961
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Associations of improvement in laboratory tests with clinical outcomes in patients with active systemic lupus erythematosus: a multinational longitudinal cohort study2022
- Author(s)
  Connelly Kathryn、Kandane-Rathnayake Rangi、、Tsutomu Takeuchi, et al.
- Journal Title
  
  The Lancet Rheumatology
  
  Volume: 4 Issue: 12 Pages: e831-e841
- DOI
  10.1016/s2665-9913(22)00307-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Abatacept ameliorates both glandular and extraglandular involvements in patients with Sjogren’s syndrome associated with rheumatoid arthritis: Findings from an open-label, multicentre, 1-year, prospective study: The ROSE (Rheumatoid Arthritis with Orencia Trial Toward Sj?gren’s Syndrome Endocrinopathy) and ROSE II trials2022
- Author(s)
  Tsuboi H, Toko H, Honda F, Abe S, Takahashi H, Yagishita M, Hagiwara S, Ohyama A, Kondo Y, Nakano K, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Fujieda Y, Atsumi T, Suzuki Y, Kawano M, Nishina N, Kaneko Y, Takeuchi T, Kobayashi H, Takei M, Ogasawara M, Tamura N, Takasaki Y, Yokota K, Akiyama Y, Mimura T, et al.
- Journal Title
  
  Modern Rheumatology
  
  Volume: 33 Issue: 1 Pages: 160-168
- DOI
  10.1093/mr/roac011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07326, KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-20K08767
[Journal Article] Efficacy and safety of anti-TNF multivalent NANOBODY compound ‘ozoralizumab’ without methotrexate co-administration in patients with active rheumatoid arthritis: A 52-week result of phase III, randomised, open-label trial (NATSUZORA trial)2022
- Author(s)
  Tanaka Yoshiya、Kawanishi Masafumi、Nakanishi Megumi、Yamasaki Hironori、Takeuchi Tsutomu
- Journal Title
  
  Modern Rheumatology
  
  Volume: ー Issue: 5 Pages: 875-882
- DOI
  10.1093/mr/roac126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Role of interferons (IFNs) in the differentiation of T peripheral helper (Tph) cells: : 1. Type I IFNs promote the differentiation of interleukin-21-producing Tph-like cells2022
- Author(s)
  Shuhei Tanemura, Hideto Tsujimoto, Noriyasu Seki, Shinji Kojima, Fumihiko Miyoshi, Kunio Sugahara, Keiko Yoshimoto, Katsuya Suzuki, Yuko Kaneko, Kenji Chiba, Tsutomu Takeuchi
- Journal Title
  
  Int Immunol
  
  Volume: 34(10) Issue: 10 Pages: 519-532
- DOI
  10.1093/intimm/dxac026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08527, KAKENHI-PROJECT-20H03720
[Journal Article] Should we consider the definition of elderly-onset rheumatoid arthritis in an aging society?2022
- Author(s)
  Uchiyama S, Takanashi S, Takeno M, Gono T, Takeuchi T, Kaneko Y, and Kuwana M.
- Journal Title
  
  Mod Rheum
  
  Volume: 32 Pages: 322-329
- Open Access
- Data Source
  KAKENHI-PROJECT-20H03720
[Journal Article] Serum cytokines and bone metabolic markers in patients with rheumatoid arthritis treated with biological disease modifying anti-rheumatic drugs2022
- Author(s)
  Tamai Hiroya、Nishina Naoshi、Kikuchi Jun、Izumi Keisuke、Otomo Kotaro、Yoshimoto Keiko、Yamaoka Kunihiro、Takeuchi Tsutomu、Kaneko Yuko
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 42 Issue: 3 Pages: 721-730
- DOI
  10.1007/s10067-022-06390-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
[Journal Article] Distinct Expression of Coinhibitory Molecules on Alveolar T Cells in Patients With Rheumatoid Arthritis Associated and Idiopathic Inflammatory Myopathy Associated Interstitial Lung Disease2021
- Author(s)
  Nakazawa Maho、Suzuki Katsuya、Takeshita Masaru、Inamo Jun、Kamata Hirofumi、Ishii Makoto、Oyamada Yoshitaka、Oshima Hisaji、Takeuchi Tsutomu
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 73 Issue: 4 Pages: 576-586
- DOI
  10.1002/art.41554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17430, KAKENHI-PROJECT-20H03720
[Journal Article] Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus2021
- Author(s)
  Suetsugu Hiroyuki、Kim Kwangwoo、Yamamoto Takuaki、Bang So-Young、Sakamoto Yuma、Shin Jung-Min、Sugano Nobuhiko、Kim Ji Soong、Mukai Masaya、Lee Yeon-Kyung、Ohmura Koichiro、Park Dae Jin、Takahashi Daisuke、Ahn Ga-Young、Karino Kohei、Kwon Young-Chang、Miyamura Tomoya、Kim Jihye、Nakamura Junichi、et al
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 31 Issue: 7 Pages: 1082-1095
- DOI
  10.1093/hmg/ddab306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10954, KAKENHI-PROJECT-21H03057, KAKENHI-PROJECT-20H03720
[Journal Article] Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease2021
- Author(s)
  Takeshita Masaru、Suzuki Katsuya、Nakazawa Maho、Kamata Hirofumi、Ishii Makoto、Oyamada Yoshitaka、Oshima Hisaji、Takeuchi Tsutomu
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 121 Pages: 102661-102661
- DOI
  10.1016/j.jaut.2021.102661
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17430, KAKENHI-PROJECT-20H03720
[Journal Article] Immunoglobulin G4?related disease and idiopathic multicentric Castleman’s disease: confusable immune-mediated disorders2021
- Author(s)
  Sasaki Takanori、Akiyama Mitsuhiro、Kaneko Yuko、Takeuchi Tsutomu
- Journal Title
  
  Rheumatology
  
  Volume: 61 Issue: 2 Pages: 490-501
- DOI
  10.1093/rheumatology/keab634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16292, KAKENHI-PROJECT-20H03720
[Journal Article] Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands2019
- Author(s)
  Takeshita Masaru、Suzuki Katsuya、Kaneda Yukari、Yamane Humitsugu、Ikeura Kazuhiro、Sato Hidekazu、Kato Shin、Tsunoda Kazuyuki、Arase Hisashi、Takeuchi Tsutomu
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 79 Issue: 1 Pages: 150-158
- DOI
  10.1136/annrheumdis-2019-215862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11853, KAKENHI-PROJECT-18K19450, KAKENHI-PUBLICLY-19H04808, KAKENHI-PROJECT-18H05279, KAKENHI-PROJECT-17H04216
[Journal Article] Clinical and immunological features of anti-centromere antibody-positive sjogren’s syndrome.2018
- Author(s)
  Tsukamoto M, Suzuki K, and Takeuchi T
- Journal Title
  
  Rheumatol Ther,
  
  Volume: 5 Pages: 499-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04216
[Journal Article] Initial presenting determines clinical entity in patients with anti-centromere antibody positivity.2018
- Author(s)
  Tsukamoto M, Suzuki K, and Takeuchi T.
- Journal Title
  
  Int J Rheum Dis
  
  Volume: ー
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04216
[Journal Article] Identification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study2016
- Author(s)
  Nakamura S, Suzuki K, Iijima H, Hata Y, Lim CR, Ishizawa Y, Kameda H, Amano K, Matsubara K, Matoba R, Takeuchi T
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 18 Issue: 1 Pages: 159-159
- DOI
  10.1186/s13075-016-1052-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09535, KAKENHI-PROJECT-26293233
[Journal Article] CD247 variants and single nucleotide polymorphisms observed in systemic lupus erythematosus patients.2013
- Author(s)
  Takeuchi Takeuchi
- Journal Title
  
  Rheumatology(Oxford)
  
  Volume: Mar 22. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] 特集自己免疫疾患の最近の話題と展望マイクロアレイを用いた自己免疫疾患の解析2013
- Author(s)
  倉沢隆彦, 鈴木勝也, 竹内勤, 他
- Journal Title
  
  Pharma Medica
  
  Volume: vol. 31 No. 1 Pages: 23-26
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] CD3 ζ defects in systemic lupus erythematosus2012
- Author(s)
  Takeuchi T
- Journal Title
  
  Ann Rheum Dis (Suppl)
  
  Volume: 71 Pages: i78-i81
- DOI
  10.1136/annrheumdis-2011-200641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591268, KAKENHI-PROJECT-22591084
[Journal Article] CD3 Zeta Defects in Systemic Lupus Erythematosus.2012
- Author(s)
  Takeuchi Takeuchi
- Journal Title
  
  Ann Rheum Dis
  
  Volume: Apr;71 Suppl 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Baseline tumor necrosis factor alpha levels predict the necessity for dose escalation of infliximab therapy in patients with rheumatoid arthritis2011
- Author(s)
  Takeuchi T, Miyasaka N, Tatsuki Y, Yano T, Yoshinari T, Abe T, Koike T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Pages: 1208-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Efficacy of tocilizumab for rheumatoid arthritis patients in daily practice in Japan-message from REACTION study2011
- Author(s)
  Yamanaka H, Tanaka Y, Inoue E, Hoshi D, Momohara S, Hanami K, Yunoue N, Saito K, Amano K, Kameda H, Takeuchi T
- Journal Title
  
  Modern Rheum
  
  Volume: 21 Pages: 122-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Clinical, radiographic, and functional effectiveness of tocilizumab for rheumatoid arthritis patients-REACTION-52 weeks study2011
- Author(s)
  Takeuchi T, Tanaka Y, Amano K, Hoshi D, Nawata M, Nagasawa H, Satoh E, Saitao K, Kaneko Y, Fukuyo S, Kurasawa T, Hanami K, Kameda H, Yamanaka H
- Journal Title
  
  Rheumatology
  
  Volume: 50 Pages: 1908-1915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Decreased mRNA expression of two Foxp3 isoforms in peripheral blood mononuclear cells from patients with rheumatoid arthritis and systemic lupus erythematosus2011
- Author(s)
  Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T
- Journal Title
  
  Int J Immunopathol and Pharmacology
  
  Volume: 24 Pages: 7-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Sensitivity and Specificity of 2010 Rheumatoid Arthritis Classification Criteria2011
- Author(s)
  Kaneko Y, Kuwana M, Kameda H, Takeuchi T., et al
- Journal Title
  
  Rheumatology
  
  Volume: 50 Pages: 1268-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Humanized anti-interieukin 6 receptor antibody (tocilizumab) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomakers, radiography, and BMI : data from the SAMURAI study2011
- Author(s)
  Hashimoto J, Garnero P, van der Heijde, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T., et al
- Journal Title
  
  Modern Rheum
  
  Volume: 21 Pages: 10-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Effectiveness and safety of adalimumab in Japanese patients with rheumatoid arthritis : Retrospective analyses of data collected during the first year of adalimumab treatment in routine clinical practice (HARMONY study)2011
- Author(s)
  Takeuchi T, Tanaka Y, Kaneko Y, Kameda H, Amano K, Yamanaka H., et.al
- Journal Title
  
  Mod Rheum
  
  Volume: 6,Sep(Online) Issue: 3 Pages: 327-38
- DOI
  10.1007/s10165-011-0516-6
- NAID
  10030782043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259, KAKENHI-PROJECT-23791120
[Journal Article] Continuation of Methotrexate resulted in better clinical and radiographic outcomes than discontinuation upon starting etanercept in patients with Rheumatoid Arthritis : 52-Week results from the JESMR Study2011
- Author(s)
  Kameda H, Tanaka Y, Yamanaka H, Takeuchi T., et.al
- Journal Title
  
  J Rheum
  
  Volume: 38 Pages: 1585-1592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Postmarketing surveillance of safety and effectiveness of etanercept in Japanese patients with Rheumatoid Arthritis2011
- Author(s)
  Koike T, Harigai M, Takeuchi T, Tanaka Y, Yamanaka H, Suzukawa M., et.al
- Journal Title
  
  Mod Rheum
  
  Volume: 21 Pages: 343-351
- NAID
  10029512752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Fc gamma receptor IIIb polymorphism and usage of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis2011
- Author(s)
  Okuyama A, Nagasawa H, Suzuki K, Kameda H, Kondo H, Amano K, Takeuchi T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Pages: 299-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Concise report : Postmarketing surveillance of tocilizumab for rheumatoid arthritis in Japan : interim analysis of 3881 patients2011
- Author(s)
  Koike T, Harigai M, Takeuchi T, Yamanaka H., et.al
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Pages: 2148-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Incidence and risk factors for serious infection in rheumatoid arthritis patients treated with tumor necrosis factor (TNF) inhibitors : a report from the registry of Japanese Rheumatoid Arthritis Patients for Long-Term Safety2011
- Author(s)
  Komano Y, Koike T, Eguchi K, Tanaka Y, Takeuchi T, Miyasana N, Harigai M., et al
- Journal Title
  
  J Rheum
  
  Volume: 38 Pages: 1258-1264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] Treating Rheumatoid Arthritis to Target : multinational recommendatios assessment questionnaire2011
- Author(s)
  Haraoui B, Smolen JS, Emery P, Takeuchi T, van der Heijde D, the Treat to Target Taskforce., et.al
- Journal Title
  
  Ann Rheum
  
  Volume: 70 Issue: 11 Pages: 1999-2002
- DOI
  10.1136/ard.2011.154179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Journal Article] IgG4-positive multi-organ lymphoproliferative syndrome manifesting as chronic symmetrical sclerosing dacryo-sialo-adenitis with subsequent secondary portal hypertension and remarkable IgG4-linked IL-4 elevation.2010
- Author(s)
  Suzuki K, Tamaru J, Okuyama A, Kameda H, Amano K, Nagasawa H, Nishi, E, Yoshimoto K, Setoyama Y, Kaneko K, Osada H, Honda N, Yasaki Y, Itoyama S, Tsuzaka K, Takeuchi T.
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1789-1791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] The comparison of efficacy and safety between continuation and discontinuation of methotrexate(MTX)at the commencement of etanercept in patients with active rheumatoid arthritis despite MTX therapy : 24-week results from the JESMR study.2010
- Author(s)
  Kameda H, Ueki Y, Saito K, Nagaoka S, Hidaka T, Atsumi T, Tsukano M, Kasama T, Shiozawa S, Tanaka Y, Takeuchi T, Japan Biological Agent Integrated Consortium(J-BASIC).
- Journal Title
  
  Rheumatology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Single Center Prospective Study of Tacrolimus Efficacy and Safety in Treatment of Various Manifestations in Systemic Lupus Erythematosus2010
- Author(s)
  Suzuki K, Kameda H, Amano K, Nagasawa H, Takei H, Nishi E, Okuyama A, Tsuzaka K, Takeuchi T
- Journal Title
  
  Rheumatology int
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] Efficacy and safety of cyclosporine A in patients with refractory systemic lupus erythematosus in a daily clinical practice.2010
- Author(s)
  Ogawa H, Kameda H, Amano K, Takeuchi, T.
- Journal Title
  
  Lupus 19
  
  Pages: 162-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Reduced expression of TCR zeta is involved in the abnormal production of cytokines by peripheral T cells of patients with systemic lupus erythematosus.2010
- Author(s)
  Yoshimoto K, Setoyama Y, Tsuzaka K, Abe T, Takeuchi T.
- Journal Title
  
  J Biomed Biotechnol
  
  Volume: Article ID 509021 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] 新薬展望2010抗リウマチ薬2010
- Author(s)
  鈴木勝也, 竹内勤
- Journal Title
  
  医薬ジャーナル増刊号(医薬ジャーナル社) Vol.46S-1
  
  Pages: 217-21
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] ADAMTS5 is a biomarker for prediction of the response to Infliximab in patients with rheumatoid arthritis.2010
- Author(s)
  Tsuzaka K, Itami Y, Takeuchi T, Shinozaki N, Morishita T
- Journal Title
  
  J Rheumatol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Efficacy and safety of cyclosporine A in patients with refractory systemic lupuserythematosus in a daily clinical practice.2010
- Author(s)
  Ogawa H, Kameda H, Amano K, Takeuchi T.
- Journal Title
  
  Lupus
  
  Volume: 19 Pages: 162-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] IgG4-related systemic disease manifesting as Mikulicz disease with subsequent secondary portal hypertension and remarkable IgG4-linked IL-4 elevation2010
- Author(s)
  Suzuki K, Tamaru J, Okuyama A, Kameda H, Amano K, Nagasawa H, Nish E, Yoshimoto K, Setoyama Y, Kaneko K, Osada H, Honda N, Sasaki Y, Itoyama S, Tsuzaka K, Takeuchi T
- Journal Title
  
  Rheumatology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] IgG4-positive mufti-organ lymphoproliferative syndrome manife sting as chronic symmetrical sclerosing dacryo-sialo-adenitis with subsequent secondary portal hypertension and remarkable IgG4-linked IL-4 elevation.2010
- Author(s)
  Suzuki K, Tamaru J, Okuyama A, Kameda H, Amano K, Nagasawa H, Nishi, E, Yoshimoto K, Setoyama Y, Kaneko K, Osada H, Honda N, Yasaki Y, Itoyama S, Tsuzaka K, Takeuchi T.
- Journal Title
  
  Rheumatology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] 新薬展望2010抗リウマチ薬2010
- Author(s)
  鈴木勝也, 竹内勤
- Journal Title
  
  医薬ジャーナル増刊号(医薬ジャーナル社) 46S-1
  
  Pages: 217-21
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] 特集臨床でわかったエビデンスType 1インターフェロンはループスだけの特徴か2009
- Author(s)
  鈴木勝也, 竹内勤
- Journal Title
  
  分子リウマチ治療 vol.2,No.3
  
  Pages: 119-22
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] Long-term safety and efficacy of tocilizumab, an anti-interleuk in(IL)-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis(the STREAM study) : evidence of safety and efficacy in a 5-year extension study.2009
- Author(s)
  Nishimoto N, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Azuma J.
- Journal Title
  
  Ann Rheum Dis 68
  
  Pages: 1580-1584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Two cases of acute exacerbation of lupus manifestation after re-treatment with rituximab in phase I/II clinical trial for refractory systemic lupus erythe matosus.2009
- Author(s)
  Suzuki K, Kameda H, Kondo K, Tanaka Y, Takeuchi T.
- Journal Title
  
  Rheumatology 48
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Single Center Prospective Study for Efficacy and Safety of Tacrolimus in Rheumatoid Arthritis.2009
- Author(s)
  Suzuki K, Kameda H, Amano K, Nagasawa H, Sekiguchi H, Nishi E, Ogawa H, Tsuzaka K, Takeuchi T.
- Journal Title
  
  Rheumatology Int 29
  
  Pages: 431-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Single Center Prospective Study of Tacrolimus Efficacy and Safety in Treatment of Rheumatoid Arthritis2009
- Author(s)
  Suzuki K, Kameda H, Amano K, Nagasawa H, Takei H, Sekiguchi N, Nishi E, Ogawa H, Tsuzaka K, Takeuchi T
- Journal Title
  
  Rheum. Int 29(4)
  
  Pages: 431-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] Impact to through serum level on Radiographic and Clinical Response to Infliximab plus Methotrexate in Patients with Rheumatoid Arthriti : results from the RISING Study.2009
- Author(s)
  Takeuchi T, Miyasaka N, Inoue K, Abe T, Koike T
- Journal Title
  
  Mod Rheumatology 19
  
  Pages: 478-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transc riptome analysis of white blood cells.2009
- Author(s)
  Tanino M, Matoba R, Nakamura S, Kameda H, Amano K, Okayama T, Nagasawa H, Suzuki K, Matsubara K, Takeuchi T.
- Journal Title
  
  Biochem Biophys Research Comm 387
  
  Pages: 261-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Sever acute thrombotic exacerbation in two cases with of anti-phospholipid syndrome after retreatment with rituximab in phase I/II clinical trial for refractory syystemic lupus erythematosus.2009
- Author(s)
  Suzuki K, Kameda H, Kondo K, Tanaka Y, Takeuchi T.
- Journal Title
  
  Rheumatology 48巻
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Severe acute thrombotic exacerbation in two cases with anti-phospholipid syndrome after retreatment with rituximab in phase I/II clinical trial for refractory systemic lupus erythematosus2009
- Author(s)
  Suzuki K, Nagasawa H, Kameda H, Amano K, Kondo T, Itoyama S, Tanaka Y, Takeuchi T
- Journal Title
  
  Rheumatology 48(2)
  
  Pages: 198-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] Two cases of acut e exacerbation of lupus manifestation a fter re-treatment with rituximab in pha se I/II clinical trial for refractory s ystemic lupus erythematosus.2009
- Author(s)
  Suzuki K, Kameda H, Kondo K, Tanaka Y, Takeuchi T.
- Journal Title
  
  Rheumato logy
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Sever acute thrombotic exacerbation in two cases with of anti-phospholipid syndrome after retreatment with rituximab in phase I/II clinical trial for refractory syystemic lupus erythematosus. .2009
- Author(s)
  Suzuki K, Kameda H, Kondo K, Tanaka Y, Takeuchi T.
- Journal Title
  
  Rheumatology 48
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] The conservative sequences in 3'UTR of TCRζ mRNA regulate the production of TCRζ and TCR/CD3 complex in SLE T cells.2008
- Author(s)
  Tsuzaka K, Itami Y, Kumazawa C, Suzuki M, Setoyama Y, Yoshimoto K, Suzuki K, Abe T, Takeuchi T.
- Journal Title
  
  Biochemical Biophysical Research Communications 367
  
  Pages: 311-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Effect of Interleukin 2 on synthesis of B cell activating factor belonging to the tumor necrosis factor family (BAFF) in human peripheral blood mononuclear cells.2008
- Author(s)
  Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T.
- Journal Title
  
  Cytokine 44巻
  
  Pages: 44-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Effect of Interleukin 2 on synthesis of B cell activating factor belonging to the tumor necrosis factor family (BAFF)in human peripheral blood mononuclear cells.2008
- Author(s)
  Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T
- Journal Title
  
  Cytokine 44
  
  Pages: 44-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Effect of Interleukin 2 on synthesis of B cell activating factor belonging to the tumor necrosis factor family (BAFF) in human peripheral blood mononuclear cells2008
- Author(s)
  Suzuki K, Setoyama Y, Yoshimoto K, Tsuzaka K, Abe T, Takeuchi T
- Journal Title
  
  Cytokine 44(1)
  
  Pages: 44-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] T The conservative sequences in 3' UTR of TCRtξ mRNA regulate the production of TCRξ and TCR/CD3 complex in SLE T cells.2008
- Author(s)
  Tsuzaka, K, Itami, Y, Kumazawa, C, Suzuki, M, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
- Journal Title
  
  BBRC 367
  
  Pages: 311-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] 特集リウマチ性疾患における腎障害ループス腎炎に対するタクロリムスの有用性2008
- Author(s)
  鈴木勝也, 竹内勤
- Journal Title
  
  リウマチ科 40(6)
  
  Pages: 604-7
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] The conservative sequences in 3'UTR of TCRζ mRNA regulate the production of TCRζ and TCR/CD3 complex in SLE T cells.2008
- Author(s)
  Tsuzaka K, Itami Y, Kumazawa C, Suzuki M, Setoyama Y, Yoshimoto K, Suzuki K, Abe T, Takeuchi T.
- Journal Title
  
  Biochemical Biophysical Research Communications 367巻
  
  Pages: 311-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591193
[Journal Article] Prospective study of low dose cyclosporine A in patients with refractory lupus nephritis2007
- Author(s)
  Ogawa, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Takei, H, Tsuzaka, K, Amano, K, d Takeuchi, T
- Journal Title
  
  Mod Rheum 17
  
  Pages: 92-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Down-regulation of Fas-ligand mRNA Shogren' syndrome patients with enlarged exocrine glands2007
- Author(s)
  Tsuzaka, K, Matsumoto, Y, Sasaki, Y, Abe, T, Tsubota, K, Takeuchi, T
- Journal Title
  
  Autoimmunity 40
  
  Pages: 497-502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] A muticenter phase I/II trial of rituximab for refractory systemic lupus erythematosus2007
- Author(s)
  Tanaka, Y, Yamamoto, K, Takeuchi, T, Nishimoto, N, Miyasaka, N, Sumida, T, Shima, Y, Takada, K, Matsumoto, I, Saito, K, Koike, T
- Journal Title
  
  Mod Rheum 17
  
  Pages: 191-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Efficacy and Safety of Tacrolimus in Patients with rheumatoid arthritis in clinical practice : Significant role of blood concentration measurement for preventing severe adverse events2007
- Author(s)
  Suzuki, K, Takei, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Nishi, E, Ogawa, H, Tsuzaka, K, Amano, K, Takeuchi, T
- Journal Title
  
  Arthritis Rheum S 35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] 話題クラスター分類の最新の情報2007
- Author(s)
  鈴木勝也, 瀬戸山由美子, 竹内勤
- Journal Title
  
  臨床検査 51(9)
  
  Pages: 983-5
- Data Source
  KAKENHI-PROJECT-19591177
[Journal Article] Platelet-Derived Growth Factor as a Therapeutic Target for systemic autoimmune diseases2007
- Author(s)
  Kameda, H, Takeuchi, T
- Journal Title
  
  Drug Target Insight 2
  
  Pages: 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] DNA microarray gene expression profile of T cells with splice variants of TCRz mRNA observed in SLE2006
- Author(s)
  Tsuzaka, K, Nozaki, K, Kumazawa, C, Shiraishi, K, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
- Journal Title
  
  J Immunol 176
  
  Pages: 949-56
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] TCRz mRNA splice variant forms observed in peripheral blood T cells from systemic lupus erythematosus patients2006
- Author(s)
  Tsuzaka, K, Nozaki, K, Kumazawa, C, Shiraishi, K, Setoyama, Y, Yoshimoto, K, Abe, T, Takeuchi, T
- Journal Title
  
  Springer Seminars in Immunopathology 28
  
  Pages: 185-93
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Molecular abnormalities of T cells in systemic lupus erythematosus2006
- Author(s)
  Takeuchi, T, Tsuzaka, T, Kameda, H, Amano, K
- Journal Title
  
  APLAR journal of Rheum 9
  
  Pages: 365-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Imatinib mesylate inhibits proliferation of rheumatoid synovial fibloblast-like cells and phosphorylation of Gab adaptor proteins activated by platelet-derived growth factor2006
- Author(s)
  Kameda, H, Ishigami, H, Suzuki, M, Abe, T, Takeuchi, T
- Journal Title
  
  Clin Exp Immunol 144
  
  Pages: 335-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Aberrant expression of BAFF in T cells of systemic lupus erythematosus, which is recapitulated by a human T cell line, Loucy2006
- Author(s)
  Yoshimoto, K, Takahashi, Y, Ogasawara, M, Setoyama, Y, Suzuki, K, Tsuzaka, K, Abe, T, Takeuchi, T
- Journal Title
  
  Int Immunol 18
  
  Pages: 1189-96
- NAID
  10020618413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] Recent advance in the treatment of interstitial lung disease in patients with polymyositis/dermatomyositis2006
- Author(s)
  Kameda, H, Takeuchi, T
- Journal Title
  
  Endocrine, metabolic & Immune disorders- Drug Targets 6
  
  Pages: 409-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Journal Article] T cell abnormalities in systemic lupus erythematosus2005
- Author(s)
  Takeuchi, T, Tsuzaka, K, Abe, T, et. al.
- Journal Title
  
  Autoimmunity 38
  
  Pages: 339-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] Therapeutic targets in misguided T cells in systemic lupus erythematosus.2005
- Author(s)
  Takeuchi T, Tsuzaka K, Kameda H, et al.
- Journal Title
  
  Current Drug Target 4
  
  Pages: 295-298
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] Therapeutic targets in misguided T cells in systemic lupus erythematosus2005
- Author(s)
  Takeuchi, T, Tsuzaka, K, Kameda, H, et. al.
- Journal Title
  
  Current Drug Target 4
  
  Pages: 295-298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] T cell abnormalities in systemic lupus erythematosus.2005
- Author(s)
  Takeuchi T, Tsuzaka K, Abe T, et al.
- Journal Title
  
  Autoimmunity 38
  
  Pages: 339-346
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] Altered expression of the T cell receptor-CD3 complex in systemic lupus erythematosus.2004
- Author(s)
  Takeuchi T, Tsuzaka K, Abe T
- Journal Title
  
  Int Rev Immunol 23
  
  Pages: 273-291
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] SLE発症前の自己抗体2004
- Author(s)
  津坂憲政, 竹内勤
- Journal Title
  
  内科 93
  
  Pages: 972-973
- Data Source
  KAKENHI-PROJECT-16590993
[Journal Article] Structural damages disturb functional improvement in patients with rheumatoid arthritis treated with etanercept
- Author(s)
  Tanaka Y, Yamanaka H, Amano K, Takeuchi T., et.al
- Journal Title
  
  Mod Rheumatology
  
  Volume: (In press)
- NAID
  10030614929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390259
[Patent] 自己免疫疾患の検出剤となるタンパク質複合体、及びその使用2019
- Inventor(s)
  竹下　勝、竹内　勤、鈴木　勝也
- Industrial Property Rights Holder
  竹下　勝、竹内　勤、鈴木　勝也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-107179
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H04216
[Patent] 関節リウマチ活動性指標を同定する方法及びそれに用いるバイオマーカー2011
- Inventor(s)
  竹内勤, 天野宏一, 石澤洋平, 中村誠二, 谷野元彦, 羽田裕子
- Industrial Property Rights Holder
  学校法人慶應義塾, 学校法人埼玉医科大学, 株式会社DNAチップ研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2011-11-17
- Overseas
- Data Source
  KAKENHI-PROJECT-23390259
[Patent] 関節リウマチ活動性指標を同定する方法及びそれに用いるバイオマーカー2011
- Inventor(s)
  竹内勤(慶應義塾大学), 天野宏一(埼玉医科大学), 石澤洋平, 中村誠二, 谷野元彦, 羽田裕子((株)DNAチップ研究所)
- Industrial Property Rights Holder
  学校法人慶應義塾, 学校法人埼玉医科大学, 株式会社DNAチップ研究所
- Filing Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] Transcriptome analysis of alveolar macrophages identifies involvement of PD-1/PD-Ls in pathogenesis of rheumatoid arthritis-associated interstitial lung disease.2021
- Author(s)
  Maho Nakazawa, Katsuya Suzuki, Masaru Takeshita, Jun Inamo, Tsutomu Takeuchi.
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03720
[Presentation] Differences of coinhibitory molecule expression on lung T cells from patients with rheumatoid arthritis- and idiopathic inflammatory myopathies-associated interstitial lung disease.2020
- Author(s)
  Maho Nakazawa, Masaru Takeshita, Katsuya Suzuki, Hisaji Oshima, Tsutomu Takeuchi.
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03720
[Presentation] Antigen-driven autoantibody production in lung lesion of systemic autoimmune diseases.2020
- Author(s)
  Masaru Takeshita, Katsuya Suzuki, Maho Nakazawa, Tsutomu Takeuchi.
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03720
[Presentation] シェーグレン症候群の病変局所における自己抗体産生から明らかになった抗セントロメア抗体の疾患分類上の意義について2019
- Author(s)
  竹下　勝、鈴木　勝也、金田　由加梨、山根　史嗣、池浦　一裕、佐藤　秀和、加藤　伸、角田　和之、荒瀬　尚、竹内　勤
- Organizer
  第6回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-17H04216
[Presentation] Reactivity of antibodies in the salivary glands of Sjögren's syndrome reveals affinity maturation in disease lesion and the significance of anti-centromere “complex” antibody in disease classification.2019
- Author(s)
  Masaru Takeshita, Katsuya Suzuki, Tsutomu Takeuchi.
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-17H04216
[Presentation] シェーグレン症候群の唾液腺における自己抗体産生2018
- Author(s)
  竹下　勝、鈴木　勝也、竹内　勤
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04216
[Presentation] DNAマイクロアレイ解析を用いた生物学的製剤のテーラーメイド医療へのアプローチ2014
- Author(s)
  鈴木勝也、竹内　勤
- Organizer
  第29回日本臨床リウマチ学会
- Place of Presentation
  福岡国際会議場３F　メインホール
- Year and Date
  2014-11-30
- Data Source
  KAKENHI-PROJECT-26293233
[Presentation] トランスクリプトミクスのリウマチ性疾患への応用2013
- Author(s)
  鈴木勝也、竹内勤
- Organizer
  第8回北海道ヤングアカデミー
- Place of Presentation
  北海道　北広島
- Invited
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] トランスクリプトミクスのリウマチ性疾患への応用2013
- Author(s)
  鈴木勝也, 竹内勤
- Organizer
  第8回北海道ヤングアカデミー
- Place of Presentation
  北広島
- Year and Date
  2013-07-19
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] DNAマイクロアレイを用いた関節リウマチ新規活動性マーカーの探索2013
- Author(s)
  鈴木勝也、中村誠二、谷野元彦、竹下勝、吉本桂子、亀田秀人、天野宏一、竹内勤
- Organizer
  第56回日本リウマチ学会学術集会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] DNAマイクロアレイを用いた関節リウマチ新規活動性マーカーの探索2013
- Author(s)
  鈴木勝也, 中村誠二, 谷野元彦, 竹下勝, 吉本桂子, 亀田秀人, 天野宏一, 竹内勤
- Organizer
  第56回日本リウマチ学会学術集会
- Place of Presentation
  東京
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] 関節リウマチの新たなバイオマーカー2012
- Author(s)
  鈴木勝也, 竹下勝, 竹内勤
- Organizer
  第2回TNF療法研究会
- Place of Presentation
  東京
- Year and Date
  2012-10-18
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] 関節リウマチの治療と新たな分子標的の探索2012
- Author(s)
  竹内勤, 鈴木勝也
- Organizer
  基盤研究所セミナー
- Place of Presentation
  大阪
- Year and Date
  2012-01-12
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] Application of transcriptomics for systemic lupus erythematosus pathogenesis analysis2012
- Author(s)
  鈴木勝也, 竹内勤
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] RA患者における日常診療下でのTocilizumabの有効性と安全性-the REACTION study 52週と全例調査報告から-イブニングセミナー2011
- Author(s)
  竹内勤
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] 生物学的製剤スイッチングの意義イブニングセミナー2011
- Author(s)
  竹内勤
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] RAの治療:新しい生物学的製剤治療抵抗性関節リウマチに対するゴリムマブ(GLM:ヒト抗TNFαモノクローナル抗体)単剤療法:52週までの有効性/安全性の解析結果ワークショップ112011
- Author(s)
  竹内勤
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] Golimumab, a human anti-TNF-α monoclonal antibody administered subcutaneously every four weeks as monotherapy in patients with active rheumatoid arthritis despitemethotrexate therapy : 4 week results of clinical and radiographic assessments2011
- Author(s)
  Tanaka Y, Harigai M, Takeuchi T, Yamanaka H, Ishiguro N, Yamamoto K, et al
- Organizer
  The annual European congress of rheumatology 2011
- Place of Presentation
  London, England
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] Targeting interferon-alpha and IL-17 in systemic autoimmune diseases. Main Symposium 1.[Novel targets for the treatment of inflammatory diseases]2011
- Author(s)
  Takeuchi T.
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] アバタセプトの最新知見-国内外の臨床試験成績から-スポンサードシンポジウム2011
- Author(s)
  竹内勤
- Organizer
  第55回日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] 免疫難病における新しいターゲット分子と制御2009
- Author(s)
  竹内勤
- Organizer
  第37回日本臨床免疫学会総会シンポジウム3
- Place of Presentation
  東京
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20591193
[Presentation] The expression of an integrin α Eβ7 may induce abnormal T cell activation.2008
- Author(s)
  K. Yoshimoto, C. Kumazawa, K. Tsuzaka, T. Abe, T. Takeuchi.
- Organizer
  9th annual meeting for European League Aginst Rheumatisam
- Place of Presentation
  フランス(パジ)
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20591193
[Presentation] The expression of an integrin αEβ7 may induce abnormal T cell activation.2008
- Author(s)
  K. Yoshimoto, C. Kumazawa, K. Tsuzaka, T. Abe, T. Takeuchi
- Organizer
  9th annual meeting for European League Aginst Rheumatisam
- Place of Presentation
  フランス(パリ)
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20591193
[Presentation] 14-kd protein binds to the conservative region in TCR zeta mRNA 3' UTR and regulates the production of TCR zeta and TCR/CD3 complex2007
- Author(s)
  Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
- Organizer
  American College of Rheumatology 71st Annual Meeting
- Place of Presentation
  Boston, U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Reguratory T cells and FOXP3 isoform expression in patients with systemic lupus erythematosus and rheumatoid arthritis2007
- Author(s)
  Suzuki K, Setoyama Y, Suzuki M, Yoshimoto K, Kameda H, Tsuzaka K, Amano K, Takeuchi T
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19591177
[Presentation] A negative role of a unique integrin alphaEbeta7 on proliferative capability of human T cell line2007
- Author(s)
  Kumazawa, C, Shiraishi, K, Tsuzaka, K, Takeuchi, T
- Organizer
  The EULAR annual congress of rheumatology
- Place of Presentation
  Barcelona, Spain
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Possible involvement of MMP in the production of soluble BAFF in human T cells2007
- Author(s)
  Yoshimoto, K, Takahashi, Y, Setoyama, Y, Suzuki, K, Tsuzaka, K, Abe, T, Takeuchi, T
- Organizer
  The EULAR annual congress of rheumatology, Barcelona
- Place of Presentation
  Spain
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Efficacy and safety of tacrolimus in patients with rheumatic disease : Appropriate clinical application for various rheumatic conditions2007
- Author(s)
  Suzuki, K, Kameda, H, Amano, K, Nagasawa, H, Sekiguchi, N, Takei, H, Nishi, E, Okuyama, A, Ogawa, H, Tsuzaka, K, Takeuchi, T
- Organizer
  American College of Rheumatology 71st Annual Meeting
- Place of Presentation
  Boston, U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Signaling defects and the consequences in Lupus T cells2007
- Author(s)
  Tsutomu, Takeuchi
- Organizer
  2007 CIS School in Systemic Autoimmune Diseases
- Place of Presentation
  Santa Fe, New Mexico
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Decreased expression of the glycosylated syndecan 4 accompanied with down-regulation of TCR zeta in SLE patient T cells2007
- Author(s)
  Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
- Organizer
  American College of Rheumatology 71st Annual Meeting
- Place of Presentation
  Boston, U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] TCR ξ and TCR/CD3 expression from the TCR C mRNA with deleted form of the conservative sequences in 3' UTR is down-regulated due to its instability2007
- Author(s)
  Tsuzaka, K, Itami, Y, Kumazawa, C, Setoyama, Y, Yoshimoto, K, Suzuki, K, Abe, T, Takeuchi, T
- Organizer
  37th Japanese society for Immunology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Possible involvement of MMP-9 in the production of BAFF in T cells2007
- Author(s)
  Yoshimoto, K, Setoyama, Y, Tsuzaka, K, Ogawa, Y, Tsubota, K, Abe, T, Takeuchi, T
- Organizer
  American uollege of Nheumatology Ylst Annual Meeting
- Place of Presentation
  Boston, U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Efficacy and Safety of Tacrolimus in Patients With Rheumatoid Arthritis in Clinical Practice : Significant Role of Blood Concentration Measurement for Preventing Severe Adverse Events2006
- Author(s)
  Suzuki, K, Takei, H, Kameda, H, Nagasawa, H, Sekiguchi, N, Nishi, E, Ogawa, H, Tsuzaka, K, Amano, K, Takeuchi, T
- Organizer
  70th Annual Meeting, Washington
- Place of Presentation
  D. C., U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Responsible region in 3'UTR of TCRz mRNA for producing TCR/CD3 including TCRz in SLE T cells2006
- Author(s)
  Tsuzaka, K, Nozaki, K, Kumazawa, C, Setoyama, Y, Shiraishi, K, Abe, T, Takeuchi, T
- Organizer
  16th European Congress of Immunology
- Place of Presentation
  Paris, France
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Aberrant expression of BAFF in SLE T cells2006
- Author(s)
  Yoshimoto, K, Takahashi, Y, Setoyama, Y, Suzuki. K, Tsuzaka. K, Abe. T, Takeuchi, T
- Organizer
  The EULAR annual congress of rheumatology
- Place of Presentation
  Amsterdam, Holland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Responsible regin in 3'UTR of TCRz mRNA for producing TCR/CD3 inclluding TCRa in SLE T cells2006
- Author(s)
  Tsutomu, Takeuchi
- Organizer
  16th European Congress off Immunology
- Place of Presentation
  SLE T cells
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Efficacy and Safety of Tacrolimus in Patients with rheumatoid arthritis in clinical practice : Significant role of blood concentration measurement for preventing severe adverse events2006
- Author(s)
  Tsutomu, Takeuchi
- Organizer
  American College of Rheumatology 70th ACR Annual Meeting
- Place of Presentation
  Washington DC, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591122
[Presentation] Identification of transcriptomewide gene expression signature on peripheral blood mononuclear cells from systemic lupus erythematosus and rheumatoid arthritis patients by high-throughput DNA sequencer
- Author(s)
  Suzuki K, Yoshimoto K, Takeshita M,Takeuchi T
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23390259
[Presentation] SLE末梢血におけるトランスクリプトームワイドの遺伝子発現解析
- Author(s)
  鈴木勝也、吉本桂子、倉沢隆彦、竹下勝、竹内勤
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390259
[]

1. TSUZAKA Kensei (00245490)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. AMANO Koichi (00175928)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
3. SUZUKI Katsuya (70306695)

# of Collaborated Projects: 6 results

# of Collaborated Products: 38 results
4. ABE Tohru (60051207)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. YOSHIMOTO Keiko (20383292)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
6. TAKESHITA Masaru (10571135)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
7. KOIDE Jun (70178193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. MATSUYAMA Takami (30145479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KAMEDA Hideto (00265795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. NAGASAWA Hayato (20306343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MORI Sigehisa (10190993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HOSONO Osamu (50190210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKANO Makoto (90101021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Yamaoka Kunihiro (20425317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 江口勝美 (30128160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐々木毅 (50110656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小池隆夫 (80146795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 長澤浩平 (00108721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 宮坂信之 (30157622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中川種昭 (00227745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 仲哲治 (30303936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 白石清之 (10383291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 浅川修一 (30231872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 近藤泰 (50626380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
25. 金子祐子 (60317112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
26. IWAMOTO Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 津坂憲政

# of Collaborated Projects: 0 results

# of Collaborated Products: 25 results
28. 角田和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 花岡洋成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 中村順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 秋山光浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
32. 川上純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 三村俊英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEUCHI Tsutomu 竹内 勤

Research Projects

Research Products

Co-Researchers

Molecular signatures in pre-RA patients by multi-omics analysisPrincipal Investigator

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Multiomics analysis of auto reactive immune cells in the inflammatory sites in autoimmune diseases.Principal Investigator

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Investigation of regulatory mechanism of secretary protein kinase and its application for treatment of rheumatoid arthritisPrincipal Investigator

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Identification and characterization of pathogenesis related molecules in early rheumatoid arthritis by DNA microarrayPrincipal Investigator

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Principal Investigator

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Analysis on signal transduction pathway through CD103 moleculePrincipal Investigator

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Molecular mechanism and its regulation of heterophilic adhesion between α E 3 7 (CD103) and E-cadherin in autoimmune epithelial injuryPrincipal Investigator

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Molecular mechanism and possible therapeutic target of BAFF upregulation in SLEPrincipal Investigator

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TAKEUCHI Tsutomu 竹内勤