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Migita Makoto  右田 真

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… Alternative Names

右田 真  ミギタ マコト

MIGITA Makoto  右田 真

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Researcher Number 50256963
Other IDs
Affiliation (Current) 2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2017: 日本医科大学, 医学部, 助教授
2014 – 2016: 日本医科大学, 医学部, 准教授
2010 – 2012: 日本医科大学, 医学部, 准教授
2007: Nippon Medical School, 医学部, Associate Professor
2004 – 2006: Nippon Medical School, Associate professor, 医学部, 助教授
2000 – 2003: Nippon Medical Univ, Dept.of Biochemistry, Assistant Professor, 医学部, 講師
1997 – 1999: 日本医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatrics / Hematology
Except Principal Investigator
Pediatrics / Pediatrics / Neurology / Human genetics
Keywords
Principal Investigator
造血幹細胞 / 臍帯血移植 / 骨髓生着 / SDF-1 / Dextran sulfate / 骨髄生着 / 遺伝子導入 / 異染性白質ジストロフィー / Gaucher病 / 細胞移植治療 … More / 先天性酵素欠損症 / 羊膜細胞 / GFP / CD24 / レトロウイルスベクター / FACS / AAVベクター … More
Except Principal Investigator
遺伝子治療 / 造血幹細胞 / AAVベクター / CXCR4 / SDF-1 / 異染性白質ジストロフィー / リソゾーム病 / Gene therapy / AAV vector / ARJP / ウイルスベクター / 幹細胞 / 人工骨髄 / パーキンソン病 / 異染性ロイコジストロフィー / Metachromatic leukodystrophy / Mannose-6 phosp[hate receptor / Lysosomal diseases / Blood brain barrier / Viral vector / トランスサイトーシス / マンノース6リン酸 / アリルスルファターゼ / マンノース-6-リン酸受容体 / 血液脳関門 / Homing of HSCs / Dextran Sulfate / 遺伝子導入 / SDF1 / Dextran sulfate / CXCR-4 / 臍帯血移植 / neural stem cells / stem cells / lysosomal disorders / cell therapy / gene therapy / 多能性骨髄幹細胞 / HIVベクター / 脂肪組織由来幹細胞 / 多能性幹細胞 / アリルサルファターゼ / 神経幹細胞 / 細胞治療 / Parkin gene / Parkinson's disease / 常染色体劣性遺伝若年性パーキンソン病 / パーキン遺伝子 / アデノ随伴ウイルスベクター / Hematopoietic stem cells / Gaucher disease / Viral vectors / Gene Therapy / フィブロネクチン / 骨髄ストローマ細胞 / Gancher病 / レトロウィルスベクター / Gaucher病 / ゴーシェ病 / MSC / 再生医療 / 血管炎 / 人口骨髄 / 脂肪由来間葉系幹細胞 / 間葉系幹細胞 / NOGマウス / 白血病幹細胞 / ニッチ / 脂肪幹細胞 / 白血球幹細胞 / 小児血液学 / 遺伝病 / 遺伝子 / TH遺伝子 / ヒト羊膜細胞 / Parkinson病 / 細胞移植治療 / 羊膜細胞 / MLD / 選択レトロウィルスベクター Less
  • Research Projects

    (13 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (19 People)
  •  Analysis of Regenerated Bone Marrow by Adipose-derived stromal cells grown on a hydroxyapatite scaffold

    • Principal Investigator
      UEDA TAKAHIRO
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Perinatal gene therapy for severe genetic diseases

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Analysis of Human Regenerated Bone Marrow and Hematopoietic StemCell/Leukemic Stem Cell Niche

    • Principal Investigator
      UEDA Takahiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Non-invasive gene therapy for inherited neurodegenerative disorders (How to cross the BBB?)

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  造血幹細胞の生着のメカニズムの解明Principal Investigator

    • Principal Investigator
      右田 真
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Therapeutic strategies for inherited neurodegerative disorders using gene transfer and stem-cell transplantation technologies

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Dextran sulfate and stromal cell derived factor-1 enhance the expression of CXCR4 and improve the homing efficiency of hematopoletic stem cells in bone marrow

    • Principal Investigator
      FUKUNAGA Yoshitaka
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  TH遺伝子を導入したヒト羊膜細胞を用いたパーキンソン病に対する細胞移植治療

    • Principal Investigator
      北村 伸
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nippon Medical School
  •  ヒト羊膜細胞をキャリアーとする酵素欠損症に対する遺伝子導入細胞移植治療の検討Principal Investigator

    • Principal Investigator
      右田 真
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  Reseach for Gene therapy of ARJP

    • Principal Investigator
      MOCHIZUKI Hideki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Neurology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  造血幹細胞移植による異染性ロイコジストロフィーの遺伝子治療法の開発

    • Principal Investigator
      大木 由加志
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  FACSによる選択性を有するウイルスベクターを用いた造血幹細胞への遺伝子導入Principal Investigator

    • Principal Investigator
      右田 真
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Nippon Medical School
  •  Hematopoietic stem cell mediated gene therapy for Gaucher disease

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Human genetics
    • Research Institution
      Nippon Medical School

All 2014 2012 2010 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

  • [Journal Article] Adipose-derived stromal cells grown on a hydroxyapatite scaffold can support hematopoiesis in regenerated bone marrow in vivo.2014

    • Author(s)
      Ueda T, Fujita A, Ogawa R, Itoh Y, Fukunaga Y, Shimada T, MigitaM.
    • Journal Title

      Cell Biologyl International

      Volume: 38 Issue: 6 Pages: 790-798

    • DOI

      10.1002/cbin.10254

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461595
  • [Journal Article] Successful gene therapy in utero for lethal murine hypophosphatasia.2012

    • Author(s)
      Sugano, H., Matsumoto, T., Miyake, K., Watanabe, A., Iijima, O., Migita, M., Narisawa, S., Millan, J.L., Fukunaga, Y., Shimada, T.
    • Journal Title

      Hum. Gene Ther.

      Volume: 23 Pages: 399-406

    • Data Source
      KAKENHI-PROJECT-22390212
  • [Journal Article] Hematopoiesis in regenerated bone marrow within hydroxyapatite scaffold.2010

    • Author(s)
      Fujita, A., Migita, M., Ueda, T., Ogawa, R., Fukunaga, Y., Shimada, T.
    • Journal Title

      Pediatr. Res.

      Volume: 68 Pages: 35-40

    • Data Source
      KAKENHI-PROJECT-22390212
  • [Journal Article] AAV1 mediated co-expression of formylglycine-generating enzyme and arylsulfatase A efficiently corrects sulfatide storage in a mouse model of mitachromatic leukodystrophy2007

    • Author(s)
      Kurai, T., Hisayasu, S., Kitagawa, R., Migita, M., Suzuki, H., Hirai, Y., Shimada, T.
    • Journal Title

      Mol.Ther. 15

      Pages: 38-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Ex vivo cell-mediated gene therapy for metachromatic leukodystrophy using neurospheres2006

    • Author(s)
      Kawabata, K., Migita, M., et al
    • Journal Title

      Brain Res. 1094

      Pages: 13-23

    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Ex vivo cell-mediated gene therapy for metachromatic leukodystrophy using neurospheres2006

    • Author(s)
      Kawabata, K., Migita, M., Mochizuki, H., Miyake, K., Igarashi, T., Fukunaga, Y., Shimada, T.
    • Journal Title

      Brain Res. 1094

      Pages: 13-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] An asymptomatic heterozygous female with Fabry disease : implications for enzyme replacement therapy2005

    • Author(s)
      Inagaki, S., Migita, M., Hayakawa, M., Yoshida, J., Ishizaki, M., Kotani, M., Sakuraba, H., Shimada, T., Murakami, M., Fukunaga, Y.
    • Journal Title

      J.Nippon Med.Sch. 72

      Pages: 387-390

    • NAID

      130004146823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] An asymptomatic heterozygous female with Fabry disease : implications for enzyme replacement therapy.2005

    • Author(s)
      Inagaki, S., Migita, M., Hayakawa, M., Yoshida, J., Ishizaki, M., Kotani, M., Sakuraba, H., Shimada, T., Murakami, M., Fukunaga, Y.
    • Journal Title

      J.Nippon Med.Sch. 72

      Pages: 387-390

    • NAID

      130004146823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Role of bone marrow cells in the healing process of mouse experimental glomerulonephritis.2005

    • Author(s)
      Hayakawa, M., Ishizaki, M., Hayakawa, J., Migita, M., Nurakami, M., Shimada, T., Fukunaga, Y.
    • Journal Title

      Ped.Research 58

      Pages: 323-328

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Osteogenic and Chondrogenic Differentiation by Adipose-derived Stem Cells Harvested from GFP Transgenic Mice.2004

    • Author(s)
      Ogawa, R., Mizuno, H., Watanabe, A., Migita, A., Shimada, T., Hyakusoku, H.
    • Journal Title

      Biochem.Biophys.Res.Commun. 23

      Pages: 871-877

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Adipogenic defferentiation by adipose-derived stem cells harvested from GEP transgenic mice -including relationship of sex differences-.2004

    • Author(s)
      Ogawa, R., Mizuno, H., Watanabe, A., Migita, M., Hyakusoku, H., Shimada, T.
    • Journal Title

      Biochem.Biophys.Res.Commun. 319

      Pages: 511-517

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Recipient non-hematopoietic bone marrow cells in the intestinal graft after fetal small intestinal transplantation.2004

    • Author(s)
      Kato, Y., Yamataka, A., Miyahara, K., Sueyoshi, N., Hayakawa, J., Hayashida, M., Migita, M., Shimada, T., Kobayashi, H., Lane, G.J., Miyano, T.
    • Journal Title

      Pediatr.Surg.Int. 20

      Pages: 1-4

    • NAID

      10018938349

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Chondrogenic and osteogenic differentiation of adipose-derived stem cells isolated from GFP transgenic mice.2004

    • Author(s)
      Ogawa, R., Mizuno, H., Hyakusoku, H.Watanabe, A., Migita, M., Shimada, T.
    • Journal Title

      J.Nippon Med.Sch. 71

      Pages: 240-241

    • NAID

      130004146741

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Home treatment with enzyme replacement therapy for Gaucher disease.2003

    • Author(s)
      Migita, M., et al.
    • Journal Title

      Pediatr. Int. 45

      Pages: 363-365

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Migration of EGFP expressing bone marrow-derived microglia/macrophage into the mice brain following permanent focal ischemia.2003

    • Author(s)
      Tanaka, R., Komine-Kobayashi, M., Mochizuki, H., Yamada, M., Furuya, T., Migita, M., Shimada, T., Mizuno, Y., Urabe, T.
    • Journal Title

      Neuroscience 117

      Pages: 531-539

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Home treatment with enzyme replacement therapy for Gaucher disease.2003

    • Author(s)
      Migita, M., Shimada, T., Hayakawa, J., Morita, T., Fukunaga, Y.
    • Journal Title

      Pediatr.Int. 45

      Pages: 363-365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta-cells.2003

    • Author(s)
      Choi, J.B., Uchino, H., Azuma, K., Iwashita, N., Tanaka, Y., Mochizuki, H., Migita, M., Shimada, T., Kawamori, R., Watada, H.
    • Journal Title

      Diabetologia 46

      Pages: 1366-1374

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders.2003

    • Author(s)
      Furuya, T., Tanaka, R., Urabe, T., Hayakawa, J., Migita, M., Shimada, T., Mizuno, Y., Mochizuki, H.
    • Journal Title

      NeuroReport 14

      Pages: 629-631

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Cardiomyocyte regeneration from circulating bone marrow cells in mice.2003

    • Author(s)
      Kuramochi, Y., Fukazawa, R., Migita, M., Hayakawa, J., Hayashida, M., Uchikoba, Y., Fukumi, D., Shimada, T., Ogawa, S.
    • Journal Title

      Pediatr.Res. 54

      Pages: 319-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Generation of a chimeric mouse reconstituted with green fluorescent protein-positive bone marrow cells : a useful model for studying the behavior of bone marrow cells in regeneration in vivo.2003

    • Author(s)
      Hayakawa, J., Migita, M., Ueda, T., Shimada, T., Fukunaga, Y.
    • Journal Title

      Int.J.Hematol. 77

      Pages: 456-462

    • NAID

      50000861650

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Glucocerebrosidase level in the cerebrospinal fluid during enzymereplacement therapy - unsuccessful treatment to the neurological abnormality of type 2 Gaucher disease.2003

    • Author(s)
      Migita M., Hamada, H., et al.
    • Journal Title

      Eur.J.Paed. 162

      Pages: 524-525

    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Home treatment with enzyme replacement therapy for Gaucher disease.2003

    • Author(s)
      Migita, M., Shimada, T., et al.
    • Journal Title

      Pediatr.Int. 45

      Pages: 363-365

    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Glucocerebrosidase level in the cerebrospinal fluid during enzymereplacement therapy -unsuccessful treatment to the neurological abnormality of type 2 Gaucher disease.2003

    • Author(s)
      Migita M., et al.
    • Journal Title

      Eur. J. Paed. 162

      Pages: 524-525

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Glucocerebrosidase level in the cerebrospinal fluid during enzymereplacement therapy -unsuccessful treatment to the neurological abnormality of type 2 Gaucher disease.2003

    • Author(s)
      Migita M., Hamada, H., Fujimura, J., Watanabe, A., Shimada, T., Fukunaga, Y.
    • Journal Title

      Eur.J.Paed. 162

      Pages: 524-525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Generation of a chimeric mouse reconstituted with green fluorescent protein-positive bone marrow cells: a useful model for studying the behaviour of bone marrow cells in regeneration in vivo.2003

    • Author(s)
      Hayakawa, J., Migita, M., et al.
    • Journal Title

      Int.J.Hematol. 77

      Pages: 456-462

    • Data Source
      KAKENHI-PROJECT-14370253
  • [Journal Article] Long-term systemic therapy of Fabry disease in a knockout mouse by adeno-associated virus-mediated muscle-directed gene transfer.2002

    • Author(s)
      Takahashi, H., Hirai, Y., Migita, M., Seino, Y., Fukuda, Y., Sakuraba, H., Kase, R., Kobayashi, T., Hashimoto, Y., Shimada, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 99

      Pages: 13777-13782

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370253
  • [Presentation] Hematopoiesis in regenerated bone marrow from adipose-derived stromal cells on the hydroxyapatite scaffold2010

    • Author(s)
      T. Ueda, A. Fujita, M. Migita, et al.
    • Organizer
      日本血液学会
    • Data Source
      KAKENHI-PROJECT-22591169
  • 1.  SHIMADA Takashi (20125074)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 2.  MOCHIZUKI Hideki (90230044)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 3.  UEDA Takahiro (20322505)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 4.  MIYAKE Koichi (90267211)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  WATANABE Atsushi (10307952)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  YAMAMOTO Masao (60089662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HATTORI Nobutaka (80218510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  URABE Takao (60291663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MIZUNO Yoshikuni (30049043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NISHI Katsunori (00138257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  FUKUNAGA Yoshitaka (50097036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大木 由加志 (20160442)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  北村 伸 (40161492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  早川 潤 (10386196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  平井 幸彦 (10089617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  鈴木 聡 (70246940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  塙 秀樹 (10256977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  久安 早苗 (00089616)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAYAKAWA Jun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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