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Ishigami Akihito  石神 昭人

… Alternative Names

ISHIGAMI Akihito  石神 昭人

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Researcher Number 50270658
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7875-7482
External Links
Affiliation (Current) 2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 副所長
Affiliation (based on the past Project Information) *help 2021 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 副所長
2013 – 2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
2017: 東京都健康長寿医療センター研究所, 老化制御研究チーム, 研究部長
2016: 東京都健康長寿医療センター研究所, 老化制御研究チーム分子老化制御, 研究副部長
2014 – 2015: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 … More
2011 – 2014: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長
2013: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究副部長
2011 – 2013: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, その他
2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 研究副部長
2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 老化制御研究チーム 分子老化制御, 研究副部長
2011: 東京都健康長寿医療センター研究所, 分子老化制御部門, 研究副部長
2008 – 2010: 東邦大学, 薬学部, 准教授
2007: 東京都老人総合研究所, 主任研究員
2007: 財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所, 主任研究員
2007: Tokyo Metropolitan Institute of Gerontology, Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Senior research scientist
2005 – 2006: Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Research scientist, 東京都老人総合研究所, 主任研究員
2004: Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Research scientist, 福祉振興財団・東京都老人総合研究所, 研究員
2003: (財)東京都高齢者研究・福祉振興財団, 東京都老人総合研究所・加齢臓器障害研究グループ, 研究員
2003: 財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所・加齢臓器障害研究グループ, 研究員
2002: 東京都老人総合研究所, 加齢臓器障害研究グループ, 研究員
1994 – 1996: (財)東京都老人総合研究所, 分子老化学研究系・細胞化学部門, 研究員 Less
Review Section/Research Field
Principal Investigator
Human pathology / Basic Section 59040:Nutrition science and health science-related / Food science / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Experimental pathology / Respiratory organ internal medicine
Except Principal Investigator
Human pathology / Circulatory organs internal medicine / Metabolomics / Respiratory organ internal medicine … More / Basic Section 59040:Nutrition science and health science-related / Basic Section 59010:Rehabilitation science-related / Basic Section 49030:Experimental pathology-related / Rehabilitation science/Welfare engineering / 細胞死(アポトーシス) / Functional biochemistry / Collagenous pathology/Allergology / Drug development chemistry / Food science / 老化(加齢) Less
Keywords
Principal Investigator
老化 / 神経変性疾患 / アルツハイマー病 / 老化細胞 / astrocyte / citrullinated protein / Alzheimer's disease / neurodegenerative disorder / アストロサイト / シトルリン化蛋白質 … More / ビタミンC / 再生医療 / 脂肪幹細胞 / 老化制御 / 1細胞解析 / Senolytic薬 / シングルセル遺伝子発現解析 / トランスクリプトーム解析 / 老化関連遺伝子 / 食品 / 脳神経疾患 / arginine / calcium / apoptosis / neuron / アルギニン / カルシウム / アポトーシス / ニューロン / proteome / aging / myelin basic protein / peptidylarginine deiminase / グリア細胞 / チュブリン / シトルリン / 脱イミノ化蛋白質 / 蛋白質脱イミノ化酵素 / プロテオーム / ミエリン塩基性蛋白質 / ペプチジルアルギニンデイミナーゼ / シトルリン化タンパク質 / 臨床検査試薬 / 認知症 / ビタミンC / 加齢疾患 / 発生 / アスコルビン酸 / 肺疾患 / COPD / 慢性閉塞性肺疾患 / 閉塞性肺疾患 … More
Except Principal Investigator
老化 / SMP30 / 酸化ストレス / ビタミンC / アポトーシス / アルツハイマー病 / 炎症 / 運動 / aging / Akt / アミロイドベータ / 遺伝子操作マウス / 心不全 / 加齢 / PAD / 糖尿病 / 喫煙 / ノックアウトマウス / フィラグリン / ケラチン / 角化 / 表皮細胞 / 脱イミノ化タンパク質 / ペプチジルアルギニンデイミナーゼ / 発がん / 代謝 / がん / DNA修復 / 栄養 / 食餌 / 肥満 / 老化関連疾患 / インスリンシグナル / カロリー制限 / ゲノム編集 / 脂肪肝 / MASH / siRNA / NASH / 肥満症 / 閉経 / サルコぺニア / DNAメチル化 / 筋肥大 / レジスタンストレーニング / 筋サテライト細胞 / エピゲノム / 性差 / サルコペニア / SICM / 半月体形成性腎炎 / SCG/Kj / 自然発症マウス / 抗好中球細胞質自己抗体 / RNAシークエンス / 位置的候補遺伝子 / ANCA / Quantitative trait loci / SICMマウス / Man-1 / NETs / SCG/Kjマウス / ANCA関連血管炎 / MPO-ANCA / SMP30ノックアウトマウス / NF-kB / COPD増悪 / タバコ煙抽出液 / 気道上皮細胞 / 気管支洗浄液 / エクソソーム / IL-8 / COX-2 / miR-146a / 慢性閉塞性肺疾患(COPD) / microRNA / 理学療法学 / 虚血モデルマウス / 血管新生因子 / glial cell / astrocyte / neuron / citrullinated protein / arginine / Alzheimer's disease / neurodegenerative disorder / ペプジルアルギニンデイミナーゼ / グリア細胞 / アストロサイト / ニューロン / シトルリン化蛋白質 / アルギニン / 神経変性疾患 / gluconolactonase / vitamin C / knockout mice / liver / apoptosis / アクチノマイシンD / TNF-α / グルコノラクトナーゼ / 肝臓 / filaggrin / keratins / cornification / keratinocytes / deiminated proteins / peptidylarginine deiminase / ペプチジルアルギニンデミナーゼ / PAD4 / 安全性予測因子 / 治療反応性予測因子 / 機能的多型 / PPID / 低疾患活動性を目標とした治療 / PAD4 / 全エクソン領域関連解析 / 核内タンパク質シトルリン化酵素 / 疾患感受性遺伝子 / 身体機能 / 治療戦略 / 高齢者 / 関節リウマチ / シトルリン化タンパク質 / ドキソルビシン / NADPH / ROS / heart failure / signal transduction / oxidative stress / doxorubcin / 繊維化阻害 / ホスホン酸 / 有機合成 / 多価フェノール / グルコサミン酸 / ベンゾフラン / 繊維化阻害剤 / 凝集阻害剤 / アルツハイマー / 糖尿病合併症 / 尿細管障害 / 糖尿病腎症 / アンジオテンシンII / 診断薬 / プロテオーム / シトルリン化 / 脳・神経 / インスリン / 生体分子 / エネルギー・糖質代謝異常 / 肺気腫 / COPD / 肺 / 呼吸器 / AChR / 神経筋シナプス / モデル動物 / MuSK / 重症筋無力症 / ストレス / コラーゲン / ノックアウト / 活性酸素 / アスコルビン酸 / カルニチン Less
  • Research Projects

    (30 results)
  • Research Products

    (335 results)
  • Co-Researchers

    (57 People)
  •  超高齢社会における高齢者の安全な再生医療を実現化するための挑戦的基礎研究Principal Investigator

    • Principal Investigator
      石神 昭人
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  老化細胞の特定と老化細胞死誘導剤Senolytic薬による老化制御の達成Principal Investigator

    • Principal Investigator
      石神 昭人
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  運動による骨格筋幹細胞のエピゲノム記憶の解明と女性のサルコペニア予防への応用

    • Principal Investigator
      町田 修一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Juntendo University
  •  Molecular Mechanisms of Age-Related Disease Prevention through Diet and Exercise Interventions Applying Genome Editing Technology

    • Principal Investigator
      Chiba Takuya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Waseda University
  •  Identification of senescent cells in the tissues of aged animals and the effect of their removal on prolonging individual life span.Principal Investigator

    • Principal Investigator
      Ishigami Akihito
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Analysis of the vascular protective genes identified by a newly established animal model of ANCA associated vasculitis.

    • Principal Investigator
      Hamano Yoshitomo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Juntendo University
  •  Development of early clinical reagents for Alzheimer's disease using citrullinated proteins as indexPrincipal Investigator

    • Principal Investigator
      Ishigami Akihito
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Effects of simultaneous deficiency of vitamins C and E on memory, learning behavior, lipid metabolism, aging and age-associated diseasePrincipal Investigator

    • Principal Investigator
      Ishigami Akihito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  アルツハイマー型認知症の発症や神経細胞傷害に及ぼす蛋白質シトルリン化の病理解析

    • Principal Investigator
      加賀美 弥生
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Establishment of treatment strategy of elderly rheumatoid arthritis based on treat-to-target strategy, Peptidylarginine Deiminase 4, and single nucleotide polymorphisms

    • Principal Investigator
      Sugihara Takahiko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Influences of Exercise after Arterial Ligation on Oxidative Stress and Pro-angiogenic Factors - Using a Mouse Model of Lower limb Ischemia -

    • Principal Investigator
      Maruoka Hiroshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Saitama Prefectural University
  •  MicroRNAs associated with smoking-induced pulmonary emphysema in senescence marker protein-30 knockout mice

    • Principal Investigator
      Sato Tadashi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Juntendo University
  •  Effect of vitamin C deficiency on the fetal growth and agingPrincipal Investigator

    • Principal Investigator
      ISHIGAMI Akihito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Development of amyloid beta aggregation inhibitor for therapeutics of Alzheimer disease

    • Principal Investigator
      SUZUKI Hideharu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Teikyo Heisei University
      Toho University
  •  A novel strategy for heart failure by anti-aging

    • Principal Investigator
      TAKEISHI Yasuchika
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Fukushima Medical University
  •  Development of diagnostic agent for dementiaPrincipal Investigator

    • Principal Investigator
      ISHIGAMI Akihito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  The role of senescence marker protein-30 (SMP30) in the progression of diabetic nephropathy

    • Principal Investigator
      HASEGAWA Goji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Pathological analysis of PAD and citrullinated proteins that triggers the onset of Alzheimer's disease

    • Principal Investigator
      HANDA Setsuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Role of SMP30 in the development of heart failure

    • Principal Investigator
      TAKEISHI Yasuchika
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Fukushima Medical University
  •  Pathogenesis and drug development using a mouse model of chronic obstructive pulmonary diseasePrincipal Investigator

    • Principal Investigator
      ISHIGAMI Akihito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所)
      Toho University
  •  Role of Senescence Marker Protein-30in Glucose Homeostasis

    • Principal Investigator
      HASEGAWA Goji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Influence of vitamin C deficiency exerts on aging, nervous system, energy metabolism and lipid metabolism

    • Principal Investigator
      HANDA Setsuko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Analysis of pathogenic mechanisms of myasthenia gravis.

    • Principal Investigator
      KUBO Sachiho
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Elucidation of the mechanism for the development of chronic obstructive pulmonary disease (COPD) by using vitamin C deficient mice

    • Principal Investigator
      SHIMADA Nobuko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  The elucidation of onset mechanism of Alzheimer's disease.Principal Investigator

    • Principal Investigator
      ISHIGAMI Akihito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Pathological analysis of abnormal activation for peptidylarginine deiminase in brain

    • Principal Investigator
      KUBO Sachiho
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare
  •  The elucidation of the apoptosis inhibitory action of SMP30.

    • Principal Investigator
      HANDA Setsuko
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      細胞死(アポトーシス)
    • Research Institution
      Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare
  •  Molecular pathological analysis of citrullinated proteins in the brain from neurodegenerative disorder patients.Principal Investigator

    • Principal Investigator
      ISHIGAMI Akihito
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Functional Significance of Protein Deimination during the Cornification of Epidermis

    • Principal Investigator
      SENSHU Tatsuo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  皮膚の防御機能の老化とタンパク質の脱イミノ化

    • Principal Investigator
      SENSHU Tatsuo
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      老化(加齢)
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology

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All Journal Article Presentation Book Patent Other

  • [Book] 寿命と成長『動物の事典』2020

    • Author(s)
      石神昭人
    • Total Pages
      746
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Book] Update on Deimination in Alzheimer’s Disease. In: Protein Deimination in Human Health and Disease.2017

    • Author(s)
      Kondo, Y., Choi, E.K., Kim, Y.S., Ishigami, A.
    • Total Pages
      466
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Book] Deimination in Prion Diseases. In: Protein Deimination in Human Health and Disease.2014

    • Author(s)
      Choi, E.K., Jang, B., Ishigami, A., Maruyama, N., Carp, R.I.,Kim, Y.K.
    • Total Pages
      433
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Book] 第11章 皮膚老化とビタミンC;” 美肌科学の最前線”2014

    • Author(s)
      石神昭人
    • Total Pages
      271
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Book] Chapter16 ビタミンC,『最新栄養学 第10版』2014

    • Author(s)
      石神昭人
    • Total Pages
      1133
    • Publisher
      建帛社
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Book] 第6章タンパク質と老化『老化の生物学 その分子メカニズムから寿命延長まで(石井直明・丸山直記 編)』2014

    • Author(s)
      後藤佐多良、石神昭人
    • Total Pages
      351
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Book] 15章 抗酸化物質・抗酸化酵素『老化の生物学 その分子メカニズムから寿命延長まで(石井直明・丸山直記 編)』2014

    • Author(s)
      石神昭人、岸本祐樹、丸山直記
    • Total Pages
      351
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Book] 老いの話題辞典2014

    • Author(s)
      石神昭人(監修)、中野展子(著者)
    • Total Pages
      234
    • Publisher
      東京堂出版
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Book] ビタミンCの事典2011

    • Author(s)
      石神昭人
    • Publisher
      東京堂出版
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice2023

    • Author(s)
      Doshida Yuta、Hashimoto Shinichi、Iwabuchi Sadahiro、Takino Yuka、Ishiwata Toshiyuki、Aigaki Toshiro、Ishigami Akihito
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 14186-14186

    • DOI

      10.1038/s41598-023-41352-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K21266, KAKENHI-PROJECT-23K24804
  • [Journal Article] Dispersant-free supra single-walled carbon nanotubes for simultaneous and highly sensitive biomolecule sensing in ex vivo mouse tissues2023

    • Author(s)
      Manikandan Ramalingam、Kim Jaehoon、Ishigami Akihito、Cho Joon Young、Kim Jung Hoon、Han Joon Tark、Lee Jaewon、Chang Seung-Cheol
    • Journal Title

      Carbon

      Volume: 213 Pages: 118275-118275

    • DOI

      10.1016/j.carbon.2023.118275

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Journal Article] Release of SMP30 in Extracellular Vesicles under Conditions of Ascorbic Acid Deficiency Is Involved with Acute Phase Response in ODS Rat2023

    • Author(s)
      Kohta Arakawa, Hirofumi Inoue, Akihito Ishigami, Ayami Sato, Yuka Takino, Miori Tanaka, Hiromu Morimoto, Nobuyuki Takahashi, Mariko Uehara
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 69 Issue: 6 Pages: 420-427

    • DOI

      10.3177/jnsv.69.420

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2023-12-31
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17697, KAKENHI-PROJECT-23K24804
  • [Journal Article] Renal Function in Aged C57BL/6J Mice Is Impaired by Deposition of Age-Related Apolipoprotein A-II Amyloid Independent of Kidney Aging2023

    • Author(s)
      Li Ying、Dai Jian、Kametani Fuyuki、Yazaki Masahide、Ishigami Akihito、Mori Masayuki、Miyahara Hiroki、Higuchi Keiichi
    • Journal Title

      The American Journal of Pathology

      Volume: - Issue: 6 Pages: 725-739

    • DOI

      10.1016/j.ajpath.2023.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16215, KAKENHI-PROJECT-21K06884, KAKENHI-PROJECT-23K10607, KAKENHI-PROJECT-23K24804
  • [Journal Article] Resveratrol Upregulates Senescence Marker Protein 30 by Activating AMPK/Sirt1-Foxo1 Signals and Attenuating H<sub>2</sub>O<sub>2</sub>-Induced Damage in FAO Rat Liver Cells2023

    • Author(s)
      Inoue H, Shimizu Y, Yoshikawa H, Arakawa K, Tanaka M, Morimoto H, Sato A, Takino Y, Ishigami A, Takahashi N, Uehara M.
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 69 Issue: 5 Pages: 388-393

    • DOI

      10.3177/jnsv.69.388

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2023-10-31
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H02938, KAKENHI-PROJECT-23K24804
  • [Journal Article] Effects of heated tobacco product aerosol extracts on DNA methylation and gene transcription in lung epithelial cells2023

    • Author(s)
      Ayami Sato, Akihito Ishigami
    • Journal Title

      Toxicology and Applied Pharmacology

      Volume: 475 Pages: 116637-116637

    • DOI

      10.1016/j.taap.2023.116637

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17697, KAKENHI-PROJECT-23K24804
  • [Journal Article] Time to Onset of Gemcitabine-induced Thrombotic Microangiopathy in a Japanese Population: A Case Series and Large-scale Pharmacovigilance Analysis2023

    • Author(s)
      TAKIGAWA MASAKI、TANAKA HIROYUKI、WASHIASHI HIROMI、ONODA TOSHIHISA、ISHIGAMI AKIHITO、ISHII TOSHIHIRO
    • Journal Title

      Cancer Diagnosis &amp; Prognosis

      Volume: 3 Issue: 1 Pages: 115-123

    • DOI

      10.21873/cdp.10188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Journal Article] Accuracy of Therapeutic Drug Monitoring of Teicoplanin at the Onset of Febrile Neutropenia2023

    • Author(s)
      Takigawa Masaki、Tanaka Hiroyuki、Suwa Junichi、Obara Tomoya、Maeda Yohei、Sato Mamoru、Shimazaki Yoshitomo、Onoda Toshihisa、Ishigami Akihito、Ishii Toshihiro
    • Journal Title

      Medicina

      Volume: 59 Issue: 4 Pages: 758-758

    • DOI

      10.3390/medicina59040758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Journal Article] Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age2023

    • Author(s)
      Kondo Yoshitaka、Aoki Hitoshi、Masuda Masato、Nishi Hiroki、Noda Yoshihiro、Hakuno Fumihiko、Takahashi Shin-Ichiro、Chiba Takuya、Ishigami Akihito
    • Journal Title

      GeroScience

      Volume: 45 Issue: 4 Pages: 2707-2726

    • DOI

      10.1007/s11357-023-00797-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05485, KAKENHI-PROJECT-23K23793, KAKENHI-PROJECT-23K24804
  • [Journal Article] Oxidative Stress Inhibits Endotoxin Tolerance and May Affect Periodontitis2023

    • Author(s)
      Yamaguchi T.、Yamamoto Y.、Egashira K.、Sato A.、Kondo Y.、Saiki S.、Kimura M.、Chikazawa T.、Yamamoto Y.、Ishigami A.、Murakami S.
    • Journal Title

      Journal of Dental Research

      Volume: 102 Issue: 3 Pages: 331-339

    • DOI

      10.1177/00220345221138523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Journal Article] Influence of oestrogen on satellite cells and myonuclear domain size in skeletal muscles following resistance exercise2022

    • Author(s)
      Hung Yung‐Li、Sato Ayami、Takino Yuka、Ishigami Akihito、Machida Shuichi
    • Journal Title

      Journal of Cachexia, Sarcopenia and Muscle

      Volume: 13 Issue: 5 Pages: 2525-2536

    • DOI

      10.1002/jcsm.13031

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K11333, KAKENHI-PROJECT-19K22820, KAKENHI-PROJECT-19K19887, KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-23K24804, KAKENHI-PROJECT-23K21588
  • [Journal Article] Compartmentalized citrullination in Muller glial endfeet during retinal degeneration2022

    • Author(s)
      Palko Sarah I.、Saba Nicholas J.、Mullane Elias、Nicholas Benjamin D.、Nagasaka Yosuke、Ambati Jayakrishna、Gelfand Bradley D.、Ishigami Akihito、Bargagna-Mohan Paola、Mohan Royce
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 9

    • DOI

      10.1073/pnas.2121875119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-23K24804
  • [Journal Article] Vitamin C Is Essential for the Maintenance of Skeletal Muscle Functions2022

    • Author(s)
      Takisawa Shoko、Takino Yuka、Lee Jaewon、Machida Shuichi、Ishigami Akihito
    • Journal Title

      Biology

      Volume: 11 Issue: 7 Pages: 955-955

    • DOI

      10.3390/biology11070955

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K11333, KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-23K21588, KAKENHI-PROJECT-23K24804
  • [Journal Article] Determination of tissue-specific interaction between vitamin C and vitamin E <i>in vivo</i> using senescence marker protein-30 knockout mice as a vitamin C synthesis deficiency model2021

    • Author(s)
      Sato Ayami、Takino Yuka、Yano Tomohiro、Fukui Koji、Ishigami Akihito
    • Journal Title

      British Journal of Nutrition

      Volume: - Issue: 6 Pages: 1-11

    • DOI

      10.1017/s0007114521004384

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17697, KAKENHI-PROJECT-22K11333, KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-23K24804
  • [Journal Article] Ascorbic acid during the suckling period is required for proper DNA demethylation in the liver2020

    • Author(s)
      Kawahori Kenichi、Kondo Yoshitaka、Yuan Xunmei、Kawasaki Yuki、Hanzawa Nozomi、Tsujimoto Kazutaka、Wada Fumiko、Kohda Takashi、Ishigami Akihito、Yamada Tetsuya、Ogawa Yoshihiro、Hashimoto Koshi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 21228-21228

    • DOI

      10.1038/s41598-020-77962-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-19H04043
  • [Journal Article] Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis2020

    • Author(s)
      Doshida Yuta、Sano Haruka、Iwabuchi Sadahiro、Aigaki Toshiro、Yoshida Masayuki、Hashimoto Shinichi、Ishigami Akihito
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 11 Pages: e0242171-e0242171

    • DOI

      10.1371/journal.pone.0242171

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Vimentin citrullination probed by a novel monoclonal antibody serves as a specific indicator for reactive astrocytes in neurodegeneration2020

    • Author(s)
      Jang B.、Kim M.J.、Lee Y.J.、Ishigami A.、Kim Y.S.、Choi E.K.
    • Journal Title

      Neuropathology and Applied Neurobiology

      Volume: 46 Issue: 7 Pages: 751-769

    • DOI

      10.1111/nan.12620

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Radiation-induced gastrointestinal syndrome is exacerbated in vitamin C insufficient SMP30/GNL knockout mice2020

    • Author(s)
      Saga R, Uchida T, Takino Y, Kondo Y, Kobayashi H, Kinoshita M, Saitoh D, Ishigami A, Makishima M
    • Journal Title

      Nutrition

      Volume: 81 Pages: 1-8

    • DOI

      10.1016/j.nut.2020.110931

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02907, KAKENHI-PROJECT-19H04043
  • [Journal Article] Decreased ADAM17 expression in the lungs of α-Klotho reduced mouse.2020

    • Author(s)
      Keiko Akasaka-Manya, Hiroshi Manya, Satomi Nadanaka, Hiroshi Kitagawa , Yoshitaka Kondo, Akihito Ishigami and Tamao Endo
    • Journal Title

      J. Biochem.

      Volume: - Issue: 5 Pages: 483-493

    • DOI

      10.1093/jb/mvz113

    • NAID

      40022226796

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07353, KAKENHI-PROJECT-19K07883, KAKENHI-PROJECT-20H03386, KAKENHI-PROJECT-19H04043
  • [Journal Article] Acerola (<i>Malpighia emarginata</i> DC.) Promotes Ascorbic Acid Uptake into Human Intestinal Caco-2 Cells via Enhancing the Gene Expression of Sodium-Dependent Vitamin C Transporter 12020

    • Author(s)
      TAKINO Yuka、AOKI Hitoshi、KONDO Yoshitaka、ISHIGAMI Akihito
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 66 Issue: 4 Pages: 296-299

    • DOI

      10.3177/jnsv.66.296

    • NAID

      130007893269

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2020-08-31
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Age-related dysfunction of p53-regulated phagocytic activity in macrophages2020

    • Author(s)
      Yamaguchi Yohko、Kaida Kohei、Suenaga Yusuke、Ishigami Akihito、Kobayashi Yoshiro、Nagata Kisaburo
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 529 Issue: 2 Pages: 462-466

    • DOI

      10.1016/j.bbrc.2020.05.121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Vitamin C deficiency causes muscle atrophy and a deterioration in physical performance.2019

    • Author(s)
      Takizawa, S., Funakoshi, T., Yatsu, T., Nagata, K., Aigaki, T., Machida, S., and Ishigami. A
    • Journal Title

      Sci. Rep.

      Volume: 9 Issue: 1 Pages: 4702-4702

    • DOI

      10.1038/s41598-019-41229-7

    • NAID

      130007919173

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07183, KAKENHI-PROJECT-15K01392, KAKENHI-PROJECT-16K12940, KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-16H03205
  • [Journal Article] Age-dependent changes in vancomycin-induced nephrotoxicity in mice2019

    • Author(s)
      Takigawa Masaki、Masutomi Hirofumi、Shimazaki Yoshitomo、Arai Tomio、Lee Jaewon、Ishii Toshihiro、Mori Yoshiko、Ishigami Akihito
    • Journal Title

      Journal of Toxicologic Pathology

      Volume: 32 Issue: 1 Pages: 57-66

    • DOI

      10.1293/tox.2018-0036

    • NAID

      130007575089

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] High-Dose Vitamin C Preadministration Reduces Vancomycin-Associated Nephrotoxicity in Mice2019

    • Author(s)
      TAKIGAWA Masaki、YATSU Tomofumi、TAKINO Yuka、MATSUMOTO Shigekiyo、KITANO Takaaki、LEE Jaewon、ARAI Tomio、TANAKA Hiroyuki、ISHII Toshihiro、MORI Yoshiko、ISHIGAMI Akihito
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 65 Issue: 5 Pages: 399-404

    • DOI

      10.3177/jnsv.65.399

    • NAID

      130007738899

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2019-10-31
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis2018

    • Author(s)
      Kim Sung-Eun、Park Ji Won、Kim Mo-Jong、Jang Byungki、Jeon Yong-Chul、Kim Hee-Jun、Ishigami Akihito、Kim Hyoung Su、Suk Ki Tae、Kim Dong Joon、Park Choong Kee、Choi Eun-Kyoung、Jang Myoung-Kuk
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 8 Pages: e0201744-e0201744

    • DOI

      10.1371/journal.pone.0201744

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017

    • Author(s)
      Suzuki Yohei、Sato Tadashi、Sugimoto Masataka、Baskoro Hario、Karasutani Keiko、Mitsui Aki、Nurwidya Fariz、Arano Naoko、Kodama Yuzo、Hirano Shin-ichi、Ishigami Akihito、Seyama Kuniaki、Takahashi Kazuhisa
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 492 Issue: 1 Pages: 74-81

    • DOI

      10.1016/j.bbrc.2017.08.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08604, KAKENHI-PROJECT-17K09668, KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-26461199
  • [Journal Article] Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies.2017

    • Author(s)
      Nakabo S, Hashimoto M, Ito S, Furu M, Ito H, Fujii T, Yoshifuji H, Imura Y, Nakashima R, Murakami K, Kuramoto N, Tanaka M, Satoh J, Ishigami A, Morita S, Mimori T, Ohmura K.
    • Journal Title

      Rheumatology (Oxford)

      Volume: in press Issue: 7 Pages: 1217-1226

    • DOI

      10.1093/rheumatology/kex088

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460649, KAKENHI-PROJECT-16K09901, KAKENHI-PROJECT-15K15104
  • [Journal Article] Bone degeneration and its recovery in SMP30/GNL-knockout mice2017

    • Author(s)
      Nishijima Kazutoshi、Ohno T.、Amano A.、Kishimoto Y.、Kondo Y.、Ishigami A.、Tanaka S.
    • Journal Title

      The journal of nutrition, health & aging

      Volume: 21 Issue: 5 Pages: 573-578

    • DOI

      10.1007/s12603-016-0841-8

    • NAID

      130007537588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] Anti-cyclic citrullinated glucose-6-phosphate isomerase peptide-7 (CCG-7) antibodies were suppressed by biologics treatment and deposited to citrullinated proteins in CD68-positive cells in the RA synovium2017

    • Author(s)
      Umeda Naoto、Matsumoto Isao、Tanaka Yuki、Kawaguchi Hoshimi、Ebe Hiroshi、Kagami Yayoi、Ishigami Akihito、Sumida Takayuki
    • Journal Title

      Modern Rheumatology

      Volume: 27 Issue: 5 Pages: 914-916

    • DOI

      10.1080/14397595.2016.1270388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells2017

    • Author(s)
      Jang Byungki、Ishigami Akihito、Kim Yong-Sun、Choi Eun-Kyoung
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 18 Issue: 11 Pages: 2258-2258

    • DOI

      10.3390/ijms18112258

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Acerola (Malpighia emarginata DC.) Juice Intake Suppresses UVB-Induced Skin Pigmentation in SMP30/GNL Knockout Hairless Mice2017

    • Author(s)
      Sato Yasunori、Uchida Eriko、Aoki Hitoshi、Hanamura Takayuki、Nagamine Kenichi、Kato Hisanori、Koizumi Takeshi、Ishigami Akihito
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 1 Pages: 0170438-0170438

    • DOI

      10.1371/journal.pone.0170438

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] Induction of peptidylarginine deiminase 2 and 3 by dibutyryl cAMP via cAMP-PKA signaling in human astrocytoma U-251MG cells2017

    • Author(s)
      Masutomi Hirofumi、Kawashima Saki、Kondo Yoshitaka、Uchida Yoshiaki、Jang Byungki、Choi Eun-Kyoung、Kim Yong-Sun、Shimokado Kentaro、Ishigami Akihito
    • Journal Title

      Journal of Neuroscience Research

      Volume: 95 Issue: 7 Pages: 1503-1512

    • DOI

      10.1002/jnr.23959

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Hypoxia-induced production of peptidylarginine deiminases and citrullinated proteins in malignant glioma cells.2016

    • Author(s)
      Sase T, Arito M, Onodera H, Omoteyama K, Kurokawa MS, Kagami Y, Ishigami A, Tanaka Y, Kato T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 482 Issue: 1 Pages: 50-56

    • DOI

      10.1016/j.bbrc.2016.10.154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15104, KAKENHI-PROJECT-16K10228
  • [Journal Article] Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease, asthma-COPD overlap syndrome, and bronchial asthma2016

    • Author(s)
      Kodama Y, Kishimoto Y, Muramatsu Y, Tatebe J, Yamamoto Y, Hirota N, Itoigawa Y, Atsuta R, Koike K, Sato T, Aizawa K, Takahashi K, Morita T, Homma S, Seyama K, Ishigami A.
    • Journal Title

      Clin Respir J

      Volume: ー Issue: 6 Pages: 1-10

    • DOI

      10.1111/crj.12436

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461199, KAKENHI-PROJECT-14J07562, KAKENHI-PROJECT-15H04505
  • [Journal Article] Involvement of senescence marker protein-30 in glucose metabolism disorder and nonalchoholic fatty liver disease.2016

    • Author(s)
      Kondo Y, Ishigami A.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: Suppl 1 Issue: S1 Pages: 4-16

    • DOI

      10.1111/ggi.12722

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] Senescence marker protein-30 deficiency impairs angiogenesis under ischemia.2016

    • Author(s)
      Yamauchi H, Miura S, Owada T, Saitoh S, Machii H, Yamada S, Ishigami A, Takeishi Y.
    • Journal Title

      Free Radic Biol Med.

      Volume: 94 Pages: 66-73

    • DOI

      10.1016/j.freeradbiomed.2016.02.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15K09143
  • [Journal Article] マウス下肢虚血の運動が酸化ストレスと血管新生因子に与える影響2016

    • Author(s)
      松本純一、金村尚彦、村田健児、亀田光宏、石神昭人、丸岡弘
    • Journal Title

      理学療法-臨床・教育・研究

      Volume: 23 Pages: 16-20

    • NAID

      130005138247

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350623
  • [Journal Article] Citrullination of glial intermediate filaments is an early response in retinal injury.2016

    • Author(s)
      Wizeman JW, Nicholas AP, Ishigami A, Mohan R.
    • Journal Title

      Mol Vis.

      Volume: 22 Pages: 1137-1155

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Vitamin C impacts anxiety-like behavior and stress-induced anorexia relative to social environment in SMP30/GNL knockout mice.2016

    • Author(s)
      Koizumi M, Kondo Y, Isaka A, Ishigami A, Suzuki E.
    • Journal Title

      Nutr Res.

      Volume: 36 Issue: 12 Pages: 379-1391

    • DOI

      10.1016/j.nutres.2016.11.006

    • NAID

      130007537603

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15K12335
  • [Journal Article] Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.2016

    • Author(s)
      Shuto T, Kamei S, Nohara H, Fujikawa H, Tasaki Y, Sugahara T, Ono T, Matsumoto C, Sakaguchi Y, Maruta K, Nakashima R, Kawakami T, Suico MA, Kondo Y, Ishigami A, Takeo T, Tanaka KI, Watanabe H, Nakagata N, Uchimura K, Kitamura K, Li JD, Kai H.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 39305-39305

    • DOI

      10.1038/srep39305

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15J09420, KAKENHI-PROJECT-16K15163
  • [Journal Article] Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice.2016

    • Author(s)
      Takahashi R, Ishigami A, Kobayashi Y, Nagata K.
    • Journal Title

      Cell Immunol.

      Volume: 304-305 Pages: 44-48

    • DOI

      10.1016/j.cellimm.2016.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15K07949
  • [Journal Article] Deficiency of Senescence Marker Protein 30 Exacerbates Cardiac Injury after Ischemia/Reperfusion.2016

    • Author(s)
      Kadowaki S, Shishido T, Sasaki T, Sugai T, Narumi T, Honda Y, Otaki Y, Kinoshita D, Takahashi T, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Ishigami A, Takeishi Y, Kubota I.
    • Journal Title

      Int J Mol Sci.

      Volume: 17 Issue: 4 Pages: 542-542

    • DOI

      10.3390/ijms17040542

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15K09143, KAKENHI-PROJECT-26461121
  • [Journal Article] Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases.2016

    • Author(s)
      Umeda N, Matsumoto I, Kawaguchi H, Kurashima Y, Kondo Y, Tsuboi H, Ogishima H, Suzuki T, Kagami Y, Sakyu T, Ishigami A, Maruyama N, Sumida T.
    • Journal Title

      Clin Rheumatol.

      Volume: 35 Issue: 5 Pages: 1181-1188

    • DOI

      10.1007/s10067-015-3082-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] High dietary intake of vitamin C suppresses age-related thymic atrophy and contributes to maintenance of immune cells in vitamin C-deficient SMP30 knockout mice.2015

    • Author(s)
      Uchio, R., Hirose, Y., Murosaki, S., Yamamoto, Y., Ishigami, A.
    • Journal Title

      Br. J. Nutr.

      Volume: 113 Issue: 4 Pages: 603-609

    • DOI

      10.1017/s0007114514003857

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] Two chalcones, 4-hydroxyderricin and xanthoangelol, stimulate GLUT4-dependent glucose uptake through the LKB1/AMP-activated protein kinase signaling pathway in 3T3-L1 adipocytes2015

    • Author(s)
      Ohta, Mitsuhiro; Fujinami, Aya; Kobayashi, Norihiro; Amano, Akiko; Ishigami, Akihito; Tokuda, Harukuni; Suzuki, Nobutaka; Ito, Fumitake; Mori, Taisuke; Sawada, Morio;
    • Journal Title

      Nutrition Research

      Volume: 35(7) Issue: 7 Pages: 618-625

    • DOI

      10.1016/j.nutres.2015.05.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-15K10726, KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-25460709
  • [Journal Article] Mass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains.2015

    • Author(s)
      Ishigami, A., Masutomi, H., Handa, S., Nakamura, M., Nakaya, S., Uchida, Y., Saito, Y., Murayama, S., Jang, B., Jeon, Y.C., Choi, E.K., Kim, Y.S., Kasahara, Y., Maruyama, N., Toda, T.
    • Journal Title

      J. Neurosci. Res.

      Volume: 93 Issue: 11 Pages: 1664-1674

    • DOI

      10.1002/jnr.23620

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Anti-inflammatory activity of SMP30 modulates NF-κB through protein tyrosine kinase/phosphatase balance.2015

    • Author(s)
      Jung, K.J., Lee, E.K., Kim, S.J., Song, C.W., Maruyama, N., Ishigami, A., Kim, N.D., Im, D.S,, Yu, B.P., Chung, H.Y.
    • Journal Title

      J. Mol. Med.

      Volume: 6 Issue: 3 Pages: 35-43

    • DOI

      10.1007/s00109-014-1219-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] アルツハイマー病とシトルリン化蛋白質2015

    • Author(s)
      石神昭人
    • Journal Title

      医学のあゆみ

      Volume: 255 Pages: 889-893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Journal Article] Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice2015

    • Author(s)
      1.Takahashi, R., Totsuka, S., Ishigami, A., Kobayashi Y., and Nagata, K.
    • Journal Title

      Geriatr. Gerontol. Internal.

      Volume: 17 Issue: 1 Pages: 1111-1111

    • DOI

      10.1111/ggi.12436

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590100, KAKENHI-PROJECT-15K07949, KAKENHI-PROJECT-15H04505
  • [Journal Article] Senescence marker protein-30/gluconolactonase deficiency exacerbates diabetic nephropathy through tubular injury in a mouse model of type 1 diabetes.2015

    • Author(s)
      Okada, H., Senmaru, T., Fukui, M., Kondo, Y., Ishigami, A., Maruyama, N., Obayashi, H., Yamazaki, M., Nakamura, N., Hasegawa, G.
    • Journal Title

      J. Diabetes. Invest.

      Volume: 6 Issue: 1 Pages: 35-43

    • DOI

      10.1111/jdi.12252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Journal Article] Age-associated decrease of senescence marker protein-30/gluconolactonase in individual mouse liver cells: Immunohistochemistry and immunofluorescence.2015

    • Author(s)
      Ishigami, A., Masutomi, H., Handa, S., Maruyama, N.
    • Journal Title

      Geriatr. Gerontol. Int.

      Volume: 15 Issue: 6 Pages: 804-810

    • DOI

      10.1111/ggi.12347

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15104, KAKENHI-PROJECT-15H04505
  • [Journal Article] Vitamin C Prevents Cigarette Smoke-Induced Pulmonary Emphysema in Mice and Provides Pulmonary Restoration.2014

    • Author(s)
      Koike K, Ishigami A, Sato Y, Hirai T, Yuan Y, Kobayashi E, Tobino K, Sato T, Sekiya M, Takahashi K, Fukuchi Y, Maruyama N, Seyama K.
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 50 Issue: 2 Pages: 347-357

    • DOI

      10.1165/rcmb.2013-0121oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790922, KAKENHI-PROJECT-24380073, KAKENHI-PROJECT-26461199
  • [Journal Article] Potato chip intake increases ascorbic acid levels and decreases reactive oxygen species in SMP30/GNL knockout mouse tissues2014

    • Author(s)
      Kondo, Y., Sakuma, R., Ichisawa, M., Ishihara, K., Kubo, M., Handa, S., Mugita, H., Maruyama, N., Koga, H., Ishigami, A.
    • Journal Title

      J Agric Food Chem

      Volume: 62(38) Issue: 38 Pages: 9286-95

    • DOI

      10.1021/jf502587j

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Effect of ascorbic acid deficiency on catecholamine synthesis in adrenal glands of SMP30/GNL knockout mice.2014

    • Author(s)
      Amano, A., Tsunoda, M., Aigaki, T., Maruyama, N., Ishigami, A.
    • Journal Title

      Eur J Nutr

      Volume: 53(1) Issue: 1 Pages: 177-85

    • DOI

      10.1007/s00394-013-0515-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Ascorbic acid prevents protein oxidation in livers of senescence marker protein-30/gluconolactonase knockout mice.2014

    • Author(s)
      Sato, Y., Amano, A., Kishimoto, Y., Takahashi, K., Handa, S., Maruyama, N., Ishigami, A.
    • Journal Title

      Geriatr Gerontol Int

      Volume: 14(4) Issue: 4 Pages: 989-95

    • DOI

      10.1111/ggi.12162

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Senescence marker protein-30 / gluconolactonase deficiency exacerbates diabetic nephropathy through tubular injury in a mouse model of type 1 diabetes2014

    • Author(s)
      Okada H, Senmaru T, Fukui M, Kondo Y, Ishigami A, Maruyama N, Obayashi H, Yamazaki M, Nakamura N, Hasegawa G
    • Journal Title

      J Diabetes Invest

      Volume: (受理、印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Journal Article] Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice2014

    • Author(s)
      Takahashi, K., Kishimoto, Y., Konishi, T., Fujita, Y., Ito, M., Shimokado, K., Maruyama, N., Ishigami, A.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1840(7) Issue: 7 Pages: 2289-98

    • DOI

      10.1016/j.bbagen.2014.03.019

    • NAID

      110009930120

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Senescence marker protein-30/Superoxide dismutase 1 double knockout mice exhibits increased oxidative stress and hepatic steatosis2014

    • Author(s)
      Kondo, Y., Masutomi, H., Noda, Y., Ozawa, Y., Takahashi, T., Handa, S., Maruyama, N., Shimizu, T., and Ishigami, A
    • Journal Title

      FEBS Open Bio

      Volume: 4 Issue: 1 Pages: 522-532

    • DOI

      10.1016/j.fob.2014.05.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23790122, KAKENHI-PROJECT-24380073
  • [Journal Article] Senescence Marker Protein-30/Gluconolactonase Expression in the Mouse Ovary during Gestation2013

    • Author(s)
      Kagami Y., Kondo Y., Handa S., Maruyama N. and Ishigami A.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 36 Issue: 12 Pages: 2005-2008

    • DOI

      10.1248/bpb.b13-00309

    • NAID

      130003382055

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790122, KAKENHI-PROJECT-24380073
  • [Journal Article] Senescence marker protein 30 has a cardio-protective role in doxorubicin-induced cardiac dysfunction2013

    • Author(s)
      Miyata M, Suzuki S, Misaka T, Shishido T, Saitoh S, Ishigami A, Kubota I, Takeishi Y
    • Journal Title

      PLoS One

      Volume: 8 Issue: 12 Pages: e79093-e79093

    • DOI

      10.1371/journal.pone.0079093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100, KAKENHI-PROJECT-24659380, KAKENHI-PROJECT-25870584
  • [Journal Article] Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction2013

    • Author(s)
      Misaka T, Suzuki S, Miyata M, Kobayashi A, Ishigami A, Shishido T, Saitoh S, Kubota I, Takeishi Y
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 439 Issue: 1 Pages: 142-147

    • DOI

      10.1016/j.bbrc.2013.08.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100, KAKENHI-PROJECT-24659380, KAKENHI-PROJECT-25870584
  • [Journal Article] Peptidylarginine deiminase and protein citrullination in prion diseases: Strong evidence of neurodegeneration.2013

    • Author(s)
      Jang, B., Ishigami, A., Maruyama, N., Carp, R.I., Kim, Y.S., Choi, E.K.
    • Journal Title

      Prion

      Volume: 7 Issue: 1 Pages: 42-46

    • DOI

      10.4161/pri.22380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590441, KAKENHI-PROJECT-24659169
  • [Journal Article] Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice.2013

    • Author(s)
      Kishimoto, Y., Kanai, T., Sato, K., Lee, J., Jeong, K.S., Shimokado, K., Maruyama, N., Ishigami, A.
    • Journal Title

      Pediatr. Res.

      Volume: 73 Issue: 5 Pages: 578-584

    • DOI

      10.1038/pr.2013.22

    • NAID

      110009674991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24380073, KAKENHI-PROJECT-24591073
  • [Journal Article] Effects of Ascorbic Acid Deficiency on Protein and Lipid Oxidation in Livers from SMP30/GNL Knockout Mice2013

    • Author(s)
      Amano, A., Sato, Y., Kishimoto, Y., Takahashi, K., Handa, S., Aigaki, T., Maruyama, N., Ishigami, A.
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 59 Issue: 6 Pages: 489-495

    • DOI

      10.3177/jnsv.59.489

    • NAID

      130003393744

    • ISSN
      0301-4800, 1881-7742
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Age-related changes of dopamine, noradrenaline, and adrenaline in adrenal glands of mice.2013

    • Author(s)
      Amano, A., Tsunoda, M., Aigaki, T., Maruyama, N., Ishigami, A.
    • Journal Title

      Geriatr. Gerontol. Int.

      Volume: 13 Issue: 2 Pages: 490-496

    • DOI

      10.1111/j.1447-0594.2012.00929.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Senescence marker protein-30 (SMP30) deficiency impairs Myocardium-induced dilation of coronary arterioles associated with reactive oxygen species2013

    • Author(s)
      Mizukami H, Saitoh S, Machii H, Yamada S, Hoshino Y, Misaka T, Ishigami A, Takeishi Y
    • Journal Title

      International Journal of Molecular Science

      Volume: 14 Issue: 5 Pages: 9408-9423

    • DOI

      10.3390/ijms14059408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100
  • [Journal Article] Coronary artery spasm related to thiol oxidation and senescence marker protein-30 in aging2013

    • Author(s)
      Yamada S, Saitoh S, Machii H, Mizukami H, Hoshino Y, Misaka T, Ishigami A, Takeishi Y
    • Journal Title

      Antioxidants & Redox Signaling

      Volume: 19 Issue: 10 Pages: 1063-1073

    • DOI

      10.1089/ars.2012.4903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100
  • [Journal Article] Deficiency of senescence marker protein 30 exacerbates angiotensin II-induced cardiac remodelling2013

    • Author(s)
      Misaka T, Suzuki S, Miyata M, Kobayashi A, Shishido T, Ishigami A, Saitoh S, Hirose M, Kubota I, Takeishi Y
    • Journal Title

      Cardiovascular Research

      Volume: 9 Issue: 3 Pages: 461-470

    • DOI

      10.1093/cvr/cvt122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100, KAKENHI-PROJECT-24659380, KAKENHI-PROJECT-25870584
  • [Journal Article] Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts.2013

    • Author(s)
      Kishimoto, Y., Saito, N., Kurita, K., Shimokado, K., Maruyama, N. Ishigami, A.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 430 Issue: 2 Pages: 579-584

    • DOI

      10.1016/j.bbrc.2012.11.110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Journal Article] Structural basis of the γ-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase.2013

    • Author(s)
      Aizawa, S., Senda, M., Harada, A., Maruyama, N., Ishida, T., Aigaki, T., Ishigami, A., Senda, T.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 1 Pages: e53706-e53706

    • DOI

      10.1371/journal.pone.0053706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24380073, KAKENHI-PROJECT-24657079, KAKENHI-PLANNED-22121005
  • [Journal Article] Lepr(db/db) Mice with Senescence Marker Protein-30 Knockout (Lepr(db/db)Smp30(Y/-) ) Exhibit increases in small dense-LDL and severe fatty liver despite being fed a standard diet.2013

    • Author(s)
      Kondo Y, Hasegawa G, Okada H, Senmaru T, Fukui M, Nakamura N, Sawada M, Kitawaki J, Okanoue T, Kishimoto Y, Amano A, Maruyama N, Obayashi H, Ishigami A
    • Journal Title

      PLoS One

      Volume: 8 Issue: 6 Pages: 65698-65698

    • DOI

      10.1371/journal.pone.0065698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591317, KAKENHI-PROJECT-23790122, KAKENHI-PROJECT-24380073
  • [Journal Article] Two novel sandwich ELISAs identify PAD4 levels and PAD4 autoantibodies in patients with rheumatoid arthritis.2013

    • Author(s)
      Ishigami, A., Uchida, Y., Miyazaki, T., Handa, S., Choi, E.K,, Kim, Y.S,, Kasahara, Y., Maruyama, N.
    • Journal Title

      Mod Rheumatol.

      Volume: 23 Issue: 4 Pages: 794-803

    • DOI

      10.1007/s10165-012-0748-0

    • NAID

      10031189176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590441, KAKENHI-PROJECT-24390228, KAKENHI-PROJECT-24659169
  • [Journal Article] Age-related oxidant stress with senescence marker protein-30 deficiency plays a pivotal role in coronary artery spasm2013

    • Author(s)
      Hoshino Y, Yamada S, Saitoh S, Machii H, Mizukami H, Miyata M, Misaka T, Ishigami A, Takeishi Y
    • Journal Title

      Coronary Artery Disease

      Volume: 24 Issue: 2 Pages: 110-118

    • DOI

      10.1097/mca.0b013e32835c8f96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100
  • [Journal Article] Synthesis and Evaluation of 4-Aryl-2(1H)-quinolinones as Potent Amyloid β Fibrillogenesis Inhibitors2012

    • Author(s)
      Yoko Shimokawa
    • Journal Title

      Heterocycles

      Volume: 85 Issue: 8 Pages: 1933-1940

    • DOI

      10.3987/com-12-12506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590022, KAKENHI-PROJECT-24590147
  • [Journal Article] Pancreatic insulin release in vitamin C-deficient senescence marker protein-30/gluconolactonase knockout mice2012

    • Author(s)
      Senmaru T, Yamazaki M, Okada H, Asano M, Fukui M, Nakamura N, Obayashi H, Kondo Y, Maruyama N, Ishigami A, Hasegawa G
    • Journal Title

      J Clin Biochem Nutr

      Volume: 50 Pages: 114-118

    • NAID

      130004466678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Journal Article] Development of a New Distyrylbenzene-Derivative Amyloid-&#946;-aggregation and Fibril Formation Inhibitor2012

    • Author(s)
      Hideharu Suzuki, Akihito Ishigami, Ayako Orimoto, Akihiro Matsuyama, Setsuko Handa, Naoki Maruyama, Yuusaku Yokoyama,a Hiroaki Okuno, and Masamichi Nakakoshi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 60 Issue: 9 Pages: 1164-1170

    • DOI

      10.1248/cpb.c12-00365

    • NAID

      130001852537

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Journal Article] Two novel sandwich ELISAs identify PAD4 levels and PAD4 autoantibodies in patients with rheumatoid arthritis.2012

    • Author(s)
      Ishigami et al.
    • Journal Title

      Mod Rheumatol.

      Volume: in press

    • NAID

      10031189176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Journal Article] Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination : links between altered multifunction of enolase and neurodegenerative diseases2012

    • Author(s)
      Jang, B., Jeon, Y. C., Choi, J. K., Park, M., Kim, J. I., Ishigami, A., Maruyama, N. Carp, R. I., Kim, Y. S., Choi, E. K
    • Journal Title

      Biochem. J

      Volume: 445 Issue: 2 Pages: 183-192

    • DOI

      10.1042/bj20120025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice2011

    • Author(s)
      Coudane, F., Mechin, M. C., Huchenq, A., Henry, J., Nachat, R., Ishigami, A., Adoue, V., Sebbag, M., Serre, G., Simon, M
    • Journal Title

      Eur. J. Dermatol

      Volume: 21 Pages: 376-384

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21697043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] 17beta-Estradiol attenuates saturated fatty acid diet-induced liver injury in ovariectomized mice by up-regulating hepatic senescence marker protein-302011

    • Author(s)
      Fukui, M., Senmaru, T., Hasegawa, G., Yamazaki, M., Asano, M., Kagami, Y., Ishigami, A., Maruyama, N., Iwasa, K., Kitawaki, J., Itoh, Y., Okanoue, T., Ohta, M., Obayashi, H., Nakamura, N
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 415 Pages: 252-257

    • URL

      http://dx.doi.org/10.1016/j.bbrc.2011.10.02

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Establishment and characterization of hepatocytes from an Immortomouse/SMP30/GNL knockout mouse hybrid lacking vitamin C to study vitamin C transport2011

    • Author(s)
      Amano, A., Handa, S., Aigaki, T., Shigemoto, K., Maruyama, N., Ishigami, A.
    • Journal Title

      Journal of biochemistry

      Volume: 150 Issue: 6 Pages: 671-678

    • DOI

      10.1093/jb/mvr109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04778, KAKENHI-PROJECT-21200023, KAKENHI-PROJECT-21590974, KAKENHI-PROJECT-21591102, KAKENHI-PROJECT-23791009, KAKENHI-PROJECT-24390228
  • [Journal Article] Time course of vitamin C distribution and absorption after oral administration in SMP30/GNL knockout mice2011

    • Author(s)
      Iwama, M., Shimokado, K., Maruyama, N., Ishigami, A
    • Journal Title

      Nutrition

      Volume: 27 Issue: 4 Pages: 471-478

    • DOI

      10.1016/j.nut.2010.04.010

    • NAID

      110008762053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice : nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins2011

    • Author(s)
      Jang, B., Shin, HY., Choi, JK., Nguyen, du PT., Jeong, BH., Ishigami, A., Maruyama, N., Carp, RI., Kim, YS., and Choi, EK
    • Journal Title

      J. Neuropathol. Exp. Neurol

      Volume: 70 Issue: 2 Pages: 116-124

    • DOI

      10.1097/nen.0b013e318207559e

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Involvement of peptidylarginine deiminase-mediated posttranslational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease2010

    • Author(s)
      Jang, B., Jin, JK., Jeon, YC., Cho, HJ., Ishigami, A., Choi, KC. Carp, RI
    • Journal Title

      Acta Neuropatho

      Volume: 119 Issue: 2 Pages: 199-210

    • DOI

      10.1007/s00401-009-0625-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Importance of research on peptidylarginine deiminase and citrullinated proteins in age related disease2010

    • Author(s)
      Ishigami, et al.
    • Journal Title

      Geriatr.Gerontol.Int.

      Volume: 10(Sup.1)

    • NAID

      10027273021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] (REVIEW ARTICLE) Importance of research on peptidylarginine deiminase and citrullinated proteins in age-related disease2010

    • Author(s)
      Ishigami, A. and Maruyama, N
    • Journal Title

      Geriatr : Gerontol. Int

      Volume: 10 Issue: s1 Pages: 53-58

    • DOI

      10.1111/j.1447-0594.2010.00593.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice2010

    • Author(s)
      Koike, K., Kondo, Y., Sekiya, M., Sato, Y., Tobino, K., Iwakami, S. I., Goto, S., Takahashi, K., Maruyama, N., Seyama, K., Ishigami, A
    • Journal Title

      Am. J. Physiol. Lung Cell Mol. Physiol

      Volume: 298 Issue: 6 Pages: 784-792

    • DOI

      10.1152/ajplung.00256.2009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty diease.2010

    • Author(s)
      Park H, Ishigami A, Shima T, Mizuno M, Maruyama N, Yamaguchi K, Mitsuyoshi H, Minami M, Yasui K, Itoh Y, Yoshikawa T, Fukui M, Hasegawa G, Nkamura N, Ohta M, Obayashi H, Okanoue T.
    • Journal Title

      J Gastroenterol 45(4)

      Pages: 426-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Journal Article] Senescence Marker Protein-30/Gluconolactonase deletion worsens glucose tolerance through impairment of acute insulin secretion.2010

    • Author(s)
      Hasegawa G, Yamasaki M, Kadono M, Tanaka M, Asano M, Senmaru T, Kondo Y, Fukui M, Obayashi H, Maruyama N, Nakamura N, Ishigami A.
    • Journal Title

      Endocrinologyl 51(2)

      Pages: 529-536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Journal Article] Vitamin C deficiency attenuates liver fibrosis by way of up-regulated peroxisome proliferator-activated receptor-gamma expression in senescence marker protein 30 knockout mice2010

    • Author(s)
      Park, J. K., Ki, M. R., Lee, H. R., Hong, I. H., Ji, A. R., Ishigami, A., Park, S. I., Kim, J. M., Chung, H. Y., Yoo, S. E., Jeong, K. S
    • Journal Title

      Hepatology

      Volume: 51 Issue: 5 Pages: 1766-1777

    • DOI

      10.1002/hep.23499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Pathophysiological significance of senescence marker protein-302010

    • Author(s)
      Maruyama, N., Ishigami, A., Kondo, Y
    • Journal Title

      Geriatr. Gerontol. Int

      Volume: 10 Issue: s1 Pages: 88-98

    • DOI

      10.1111/j.1447-0594.2010.00586.x

    • NAID

      10027273261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Over-expression of Senescence Marker Protein-30 Decreases Reactive Oxygen Species in Human Hepatic Carcinoma Hep G2 cells2009

    • Author(s)
      Handa, S., Maruyama, N. and Ishigami, A.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 32 Pages: 1645-1648

    • NAID

      130000116921

    • URL

      http://dx.doi.org/10.1248/bpb.32.1645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Senescence marker protein 30 is up-regulated in kainate-induced hippocampal damage through ERK-mediated astrocytosis2009

    • Author(s)
      Son, T. G., Park, H. R., Kim, S. J., Kim, K., Kim, MS., Ishigami, A., Handa, S., Maruyama, N. Chung, H. Y. and Lee, J
    • Journal Title

      J. Neurosci. Res

      Volume: 87 Issue: 13 Pages: 2890-2897

    • DOI

      10.1002/jnr.22122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392, KAKENHI-PROJECT-21590974
  • [Journal Article] 老化肺・慢性閉塞性肺疾患(COPD)モデルマウス2009

    • Author(s)
      小池建吾, 石神昭人, 瀬山邦明
    • Journal Title

      ファルマシア 45

      Pages: 1082-1086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease2009

    • Author(s)
      Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N. and Ishigami, A
    • Journal Title

      Biomed. Res

      Volume: 30 Pages: 227-233

    • NAID

      130004903756

    • URL

      http://dx.doi.org/10.2220/biomedres.30.227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Journal Article] Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease.2009

    • Author(s)
      Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N. and Ishigami, A.
    • Journal Title

      Biomed. Res.

      Pages: 0-0

    • NAID

      130004903756

    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] カルニチン生合成系へのビタミンCの関与2009

    • Author(s)
      古澤元、佐藤安訓、田中康一、井内陽子、天野晶子、岩間水輝、近藤嘉高、半田節子、村田晃、錦見盛光、後藤佐多良、丸山直記、高橋良哉、石神昭人
    • Journal Title

      ビタミン 83

      Pages: 287-289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] 瀬山邦明老化肺性閉塞性肺疾患(COPD)モデルマウス2009

    • Author(s)
      小池建吾、石神昭人
    • Journal Title

      ファルマシア

      Volume: 45 Pages: 1082-1086

    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Over-expression of Senescence Marker Protein-30 Decreases Reactive Oxygen Species in Human Hepatic Carcinoma Hep G2 cells2009

    • Author(s)
      Handa, S., Maruyama, N. and Ishigami, A
    • Journal Title

      Biol. Pharm. Bull

      Volume: 32 Pages: 1645-1648

    • NAID

      130000116921

    • URL

      http://dx.doi.org/10.1248/bpb.32.1645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008

    • Author(s)
      Kondo, Y., Sasaki, T., Sato, Y., Amano, A., Iwama, M., Handa, S., Shimada, N., Fukuda, M., Akita, M., Lee, J., Jeong, KS., Maruyama, N. and Ishigami, A.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 291-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.2008

    • Author(s)
      Kondo, Y., Sasaki, T., Sato, Y., Amano, A., Iwama, M., Handa, S., Shimada, N., Fukuda, M., Akita, M., Lee, J., Jeong, KS., Maruyama, N. and Ishigami, A.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 291-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める.2008

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める.2008

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める2008

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める.2008

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める.2008

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Vitamin C is not essential for carnitine biosynthesis in vivo: Verification in vitamin C-depleted SMP30/GNL knockout mice.2008

    • Author(s)
      Furusawa, H., Sato, Y., Tanaka, Y., Inai, Y., Amano, A., Iwama, M., Kondo, Y., Handa, S., Murata, A., Nishikimi, M., Goto, S., Maruyama, N., Takahashi, R. and Ishigami, A.
    • Journal Title

      Biol. Pharm. Bull. 31

      Pages: 1673-1679

    • NAID

      110007338150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] Hepatoprotective effect of Arazyme on CCl_4-induced acute hepatic injury in SMP30 knock-out mice.2008

    • Author(s)
      Park, JK., Jeong, DH., Park, HY., Son, KH., Shin, DH., Do, SH., Yang, HJ., Yuan, DW., Hong, IH., Goo, MJ., Lee, HR., Ki, MR., Ishigami, A, and Jeong, KS.
    • Journal Title

      Toxicology 256

      Pages: 132-141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice.2008

    • Author(s)
      Sato, Y., Kajiyama, S., Amano, A., Kondo, Y., Sasaki, T., Handa, S., Takahashi, R., Fukui, M., Hasegawa, G., Nakamura, N., Fujinawa, H., Mori, T., Ohta, M., Obayashi, H., Maruyama, N. and Ishigami, A.
    • Journal Title

      Biochem. Biophys. Res. Commun. 375

      Pages: 346-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] Hepatoprotective effect of Arazyme on CCl_4-induced acute hepatic injury in SMP30 knock-out mice.2008

    • Author(s)
      Park, JK., Jeong, DH., Park, HY., Son, KH., Shin, DH., Do, SH., Yang, HJ., Yuan, DW., Hong, IH., Goo, MJ., Lee, HR., Ki, MR., Ishigami A., and Jeong, KS.
    • Journal Title

      Toxicology 256

      Pages: 132-142

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める2008

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 82

      Pages: 39-42

    • NAID

      110006571397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] Hepatoprotective effect of Arazyme on CCl_4-induced acute hepatic injury in SMP30 knock-out mice.2008

    • Author(s)
      Park, JK., Jeong, DH., Park, HY., Son, KH., Shin, DH., Do, SH., Yang, HJ., Yuan, DW., Hong, IH., Goo, MJ., Lee, HR., Ki, MR., Ishigami, A, and Jeong, KS.
    • Journal Title

      Toxicology 256

      Pages: 132-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A., et. al.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響.2007

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] (REVIEW ARTICLE) Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A. and Maruyama, N.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響.2007

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] Microglial expression of peptidylarginine deiminase 2 in prenatal rat brain.2007

    • Author(s)
      Asaga, H. and Ishigami, A.
    • Journal Title

      Cell. Mol. Biol. Lett. 12

      Pages: 536-544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Significance of SMP30 in gerontology2007

    • Author(s)
      Ishigami A, Maruyama N.
    • Journal Title

      Geriatrics and Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Data Source
      KAKENHI-PROJECT-19590374
  • [Journal Article] Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A., et. al.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響.2007

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響.2007

    • Author(s)
      石神 昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A, et. al.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Significance of SMP30 in Gerontology2007

    • Author(s)
      Ishigami, A. and Maruyama, N.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] expression of peptidylarginine deiminase 2 in prenatal rat brain2007

    • Author(s)
      Asaga, H. and Ishigami, A
    • Journal Title

      Cell.Mol.Biol.Lett. 12

      Pages: 536-544

    • Data Source
      KAKENHI-PROJECT-19590374
  • [Journal Article] (REVIEW ARTICLE) Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A. and Maruyama, N.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] Significance of SMP30 in Gerontology.2007

    • Author(s)
      Ishigami, A., et. al.
    • Journal Title

      Geriatrics & Gerontology International 7

      Pages: 316-325

    • NAID

      10020020578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響2007

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Journal Article] ビタミンCの不足が老化に及ぼす影響2007

    • Author(s)
      石神昭人
    • Journal Title

      ビタミン 81

      Pages: 303-308

    • NAID

      110006368521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Journal Article] Accelerated tubular cell senescence in SMP30 knockout mice.2006

    • Author(s)
      Yumura, W., Imasawa, T., Suganuma, S., Ishigami. A., Handa, S., Kubo, S. and Maruyama, N.
    • Journal Title

      Histol. Histopathol. 21

      Pages: 1151-1156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Senescence Marker Protein-30 Protects Mice Lungs from Oxidative Stress, Aging and Smoking2006

    • Author(s)
      Sato, T., Seyama, K., Sato, Y., Mon, H., Souma, S., Akiyoshi, T., Kodama, Y., Mori, T., Goto, S., Takahashi, K., Fukuchi, Y., Maruyama, N., and Ishigami, A.
    • Journal Title

      Am. J. Respir. Crit. Care Med 174

      Pages: 530-237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] The redox-sensitive DNA binding sites responsible for age-related downregulation of SMP30 by ERK pathway and reversal by calorie restriction.2006

    • Author(s)
      Jung, K.J., Maruyama, N., Ishigami, A., Yu, BP. and Chung, H.Y.
    • Journal Title

      Antioxid. Redox Signal. 8

      Pages: 671-680

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] The increased protein oxidation and the altered expression of Ca^<2+> regulatory proteins in senescence marker protein 30 deficient brain.2006

    • Author(s)
      Son, T.G., Zou, Y., Jung, K.J., Je, J.H., Yu, B.P., Ishigami, A., Maruyama, N. and Lee, J.
    • Journal Title

      Mech. Aging Dev. 127

      Pages: 451-457

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] A selective NFkappaB inhibitor, DHMEQ, reduced atherosclerosis in apoE-deficient mice.2006

    • Author(s)
      Chiba, T., Kondo, Y., Shinozaki, S., Kaneko, E., Ishigami, A., Maruyama, N., Umezawa, K. and Shimokado, K.
    • Journal Title

      J. Atheroscler Thromb. 6

      Pages: 308-313

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Senescence Marker Protein 30 Functions as Gluconolactonase in L-Ascorbic Acid Biosynthesis and Its Knockout Mice Are Prone to Scurvy.2006

    • Author(s)
      Kondo Y, Inai Y, Sato Y, Handa S, Kubo S, Shimokado K, Goto S, Nishikimi M, Maruyama N, Ishigami A.
    • Journal Title

      Proc.Nat.Acad.Sci.USA 103

      Pages: 5723-5728

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Senescence Marker Protein 30 Functions as Gluconolactonase in L-Ascorbic Acid Biosynthesis and Its Knockout Mice Are Prone to Scurvy.2006

    • Author(s)
      Kondo, Y., Inai, Y., Sato, Y., Handa, S., Kubo, S., Shimokado, K., Goto, S., Nishikimi, M., Maruyama, N., and Ishigami, A.
    • Journal Title

      Proc. Nat. Acad. Sci. USA 103

      Pages: 5723-5728

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Journal Article] Senescence Marker Protein-30 (SMP30) induces formation of microvilli and bile canaliculi in Hep G2 cells.2005

    • Author(s)
      Ishigami, A., Fujita, T., Inoue, H., Handa, S., Kubo, S., Kondo, Y., Maruyama, N.
    • Journal Title

      Cell & Tissue Res. 320

      Pages: 243-249

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Abnormal accumulation of deiminated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami, A., Ohsawa, T., Hiratsuka, M., Taguchi, H.et al.
    • Journal Title

      J.Neurosci.Res. (in press)

    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Abnormal accumulation of deiminated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami, A, Ohsawa, T, Hiratsuka, M, Taguchi, H, Kobayashi, S, Saito, Y, Murayama, S, Asaga, H, Toda, T, Kimura, N.Maruyama, N.
    • Journal Title

      J.Neurosci.Res. 80

      Pages: 120-128

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] アルツハイマー病でのシトルリン化蛋白質の異常な蓄積2005

    • Author(s)
      石神昭人 他
    • Journal Title

      日本未病システム学会雑誌 11

      Pages: 84-85

    • NAID

      130004185736

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] アルツハイマー病でのシトルリン化蛋白質の異常な蓄積2005

    • Author(s)
      石神昭人 他
    • Journal Title

      日本未病システム学会雑誌 1

      Pages: 84-85

    • NAID

      130004185736

    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami A. et al.
    • Journal Title

      J. Neurosci. Res. 80

      Pages: 120-128

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Abnormal accumulation of deiminated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami, A., Ohsawa, T., Hiratsuka, M., Taguchi, H., Kobayashi, S., Saito, Y., Murayama, S., Asaga, H., Toda, T., Kimura, N., Maruyama, N.
    • Journal Title

      J.Neurosci.Res. 80

      Pages: 120-128

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] 蛋白質のシトルリン化と病態2005

    • Author(s)
      丸山直記, 石神昭人
    • Journal Title

      最新医学 60

      Pages: 2498-2501

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Senescence Marker Protein-30 (SMP30) induces formation of microvilli and bile canaloculi in hep G2 cells.2005

    • Author(s)
      Ishigami et al.
    • Journal Title

      Cell & Tissue Res. 320

      Pages: 243-249

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Abnormal accumulation of deiminated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami, A., Ohsawa, T.et al.
    • Journal Title

      J.Neurosci.Res. 80

      Pages: 120-128

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Immunohistochemical localization of senescence marker protein-30 (SMP30) in the submandibular gland and ultrastructural changes of the granular duct cells in SMP30 knockout mice.2005

    • Author(s)
      Ishii, K., Tsubaki, T., Fujita, K., Ishigami, A., Maruyama, N., Akita, M.
    • Journal Title

      Histol.Histopathol. 20

      Pages: 761-768

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Citrullination preferentially proceeds in glomerular Bowman's capsule and increases in obstructive nephropathy.2005

    • Author(s)
      Feng D, Imasawa T, Nagano T, Kikkawa M, Takayanagi K, Ohsawa T, Akiyama K, Ishigami A, Toda T, Mitarai T, Machida T, Maruyama N.
    • Journal Title

      Kidney Int. 68

      Pages: 84-95

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.2005

    • Author(s)
      Ishigami A. et al.
    • Journal Title

      J.Neurosci.Res. 80

      Pages: 120-128

    • Data Source
      KAKENHI-PROJECT-17590326
  • [Journal Article] Senescence Marker Protein-30(SMP30) induces formation of microvilli and bile canaliculi in Hep G2 cells.2005

    • Author(s)
      Ishigami et al.
    • Journal Title

      Cell & Tissue Res. 320

      Pages: 243-249

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span.2004

    • Author(s)
      Ishigami, A., Kondo, Y., Nanba, R., Ohsawa, T., Handa, S.et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 315

      Pages: 575-580

    • NAID

      40006236477

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Modulation of gene expression of SMP-30 by LPS and calorie restriction during aging process.2004

    • Author(s)
      Jung, K.J., Ishigami, A., Maruyama, N., Takahashi, R.et al.
    • Journal Title

      Exp.Gerontol. 39

      Pages: 1169-1177

    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Senescence Marker Protein-30 Knockout Mouse as an Aging Model.2004

    • Author(s)
      Maruyama, N., Ishigami, A., Kuramoto.M..Handa.S.et al.
    • Journal Title

      Ann.NY Acad.Sci. 1019

      Pages: 383-387

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span.2004

    • Author(s)
      Ishigami, A., Kondo, Y., Nanba, R., Ohsawa, T., Handa, S.et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 315

      Pages: 575-580

    • NAID

      40006236477

    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] シトルリン化蛋白質と関節リウマチ2004

    • Author(s)
      石神昭人, 丸山直記
    • Journal Title

      医学のあゆみ 211

      Pages: 253-254

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Modulation of gene expression of SMP-30 by LPS and calorie restriction during aging process.2004

    • Author(s)
      Jung, K.J., Ishigami, A., Maruyama, N., Takahashi, R.et al.
    • Journal Title

      Exp.Gerontol. 39

      Pages: 1169-1177

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate (DFP) in the liver.2004

    • Author(s)
      Kondo, Y., Ishigami, A., Kubo, S., Handa, S.et al.
    • Journal Title

      FEBS Lett. 570

      Pages: 57-62

    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Senescence marker protein-30 knockout mouse as a novel murine model of senile lung.2004

    • Author(s)
      Mori, T., Ishigami, A., Seyama, K., Onai, R., Kubo, S.et al.
    • Journal Title

      Pathol.Int. 54

      Pages: 167-173

    • NAID

      10013056213

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate (DFP) in the liver.2004

    • Author(s)
      Kondo, Y., Ishigami, A., Kubo, S., Handa, S.et al.
    • Journal Title

      FEBS Lett. 570

      Pages: 57-62

    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] Senescence Marker Protein-30 Knockout Mouse as an Aging Model.2004

    • Author(s)
      Maruyama, N., Ishigami, A., Kuramoto, M., Handa, S.et al.
    • Journal Title

      Ann.NY Acad.Sci. 1019

      Pages: 383-387

    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I.2003

    • Author(s)
      Guerrin, M., Ishigami, A., Mechin, MC., Nachat, R., Valmary, S., Sebbag, M., Simon, M., Senshu, T., Serre, G.
    • Journal Title

      Biochem.J. 370

      Pages: 167-174

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I2003

    • Author(s)
      Guerrin, M., Ishigami, A.et al.
    • Journal Title

      Biochem.J. 370

      Pages: 167-174

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Protein deimination and peptidylarginine deiminase expression during cornification of rat epidermal keratinocytes.2002

    • Author(s)
      Ishigami, A., Asaga, H., Ohsawa, T., Akiyama, K., Maruyama, N.
    • Journal Title

      Biomed.Res. 23

      Pages: 145-151

    • NAID

      130004713403

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Human peptidylarginine deiminase type II : Molecular cloning, gene organization and expression in human skin.2002

    • Author(s)
      Ishigami, A., Ohsawa, T.et al.
    • Journal Title

      Arch.Biochem.Biophys. 407

      Pages: 25-31

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Human peptidylarginine deiminase type II : Molecular cloning, gene organization and expression in human skin.2002

    • Author(s)
      Ishigami, A., Ohsawa, T., Asaga, H., Akiyama, K, Kuramoto, M., Maruyama, N.
    • Journal Title

      Arch.Biochem.Biophys. 407

      Pages: 25-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Protein deimination and peptidylarginine deiminase expression during cornification of rat epidermal keratinocytes.2002

    • Author(s)
      Ishigami, A., Asaga, H., et al.
    • Journal Title

      Biomed.Res. 23

      Pages: 145-151

    • NAID

      130004713403

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Increased and type II-specific expression of peptidylarginine deiminase in activated microglia but not hyperplastic astrocytes following kainic acid-evoked neurodegeneration in the rat brain.2002

    • Author(s)
      Asaga, H., Akiyama, K., Ohsawa, T., Ishigami, A.
    • Journal Title

      Neurosci.Lett. 326

      Pages: 129-132

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570210
  • [Journal Article] Accelerated tubular cell senescence in SMP30 knockout mice.

    • Author(s)
      Yumura, W, Imasawa, T., Suganuma, S., Ishigami, A., Handa, S., Kubo, S., Maruyama, N.
    • Journal Title

      Histol.Histopathol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] The increased protein oxidation and the altered expression of Ca2+ regulatory proteins in senescence marker protein 30 deficient brain.

    • Author(s)
      Son, T.G., Zou, Y., Jung, K.J., Je, J.H., Yu, B.P., Ishigami, A., Maruyama, N., Lee, J.
    • Journal Title

      Mech.Aging Dev. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Journal Article] The redox-sensitive DNAbinding sites responsible for the age-related down-regulation of SMP30 by the ERK pathway and its reversal by calorie restriction.

    • Author(s)
      Jung, K.J., Maruyama, N., Ishigami, A., Yu, B.P., Chung, H.Y.
    • Journal Title

      Antioxidants & Redox Signaling (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603010
  • [Patent] アルツハイマー病の診断を補助する方法及びアルツハイマー病の診断薬2017

    • Inventor(s)
      石神昭人、近藤嘉高、佐久拓弥、内田好昭
    • Industrial Property Rights Holder
      石神昭人、近藤嘉高、佐久拓弥、内田好昭
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] Epigenetic changes due to smoking and aging: What is the impact of heated tobacco products?2023

    • Author(s)
      Ayami Sato, Akihito Ishigami
    • Organizer
      The 40th Korean Society for Gerontology and Korea-Japan Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] ドキソルビシンによる老化誘導が老化関連遺伝子の発現に及ぼす影響.2023

    • Author(s)
      土志田裕太、橋本真一、岩淵禎弘、滝野有花、石渡俊行、相垣敏郞、石神昭人
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] 喫煙によるエピジェネティクス変化と老化 -加熱式たばこの影響は?.2023

    • Author(s)
      佐藤綾美、石神昭人
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effect of ascorbate on histone demethylation during C2C12 cells differentiation.2023

    • Author(s)
      Noritsugu Osakabe, Ayami Sato, Jaewon Lee, Shuichi Machida, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Identification of age-associated genes in liver of aged mice.2023

    • Author(s)
      Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino, Toshiyuki Ishiwata, Toshiro Aigaki, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effect of heated tobacco products aerosol extracts on DNA methylation in lung derived cells.2023

    • Author(s)
      Ayami Sato, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effects of resistance training on cellular senescence in aging skeletal muscle.2023

    • Author(s)
      Yung-Li HUNG, Ayami SATO, Yuka TAKINO, Akihito ISHIGAMI, Shuichi MACHIDA
    • Organizer
      第100回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] 加齢および性差が骨格筋リボソーム量に及ぼす影響.2023

    • Author(s)
      賦舩翔太、洪永豊、佐藤綾美、滝野有花、石神昭人、町田修一
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] マウス肝臓実質細胞におけるp16INK4a過剰発現による影響.2023

    • Author(s)
      下田友貴、土志田裕太、Jaewon Lee、石神昭人
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] 老化指標DNAメチル化に影響を及ぼす因子の評価.2023

    • Author(s)
      佐藤綾美、石神昭人
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effect of p16INK4a overexpression in primary cultured hepatocytes from young mice.2023

    • Author(s)
      Tomoki Shimoda, Yuta Doshida, Jaewon Lee, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] 筋力トレーニングによる筋サテライト細胞の増加に及ぼす加齢および性差の影響.2023

    • Author(s)
      洪永豊、佐藤綾美、滝野有花、石神昭人、町田修一
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] シングルセル解析を用いた老齢マウス肝臓での老化肝細胞の指標となる遺伝子の同定.2023

    • Author(s)
      土志田裕太、橋本真一、岩淵禎弘、滝野有花、石渡俊行、相垣敏郎、石神昭人
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] itamin C is essential for the maintenance of skeletal muscle functions.2023

    • Author(s)
      Yuka Takino, Jaewon Lee, Shuichi Machida, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] ビタミンCによる表皮角化過程でのエピジェネティクス制御2022

    • Author(s)
      佐藤綾美、松井美緒、滝野有花、佐藤安訓、斉藤紀克、大澤肇、石神昭人
    • Organizer
      日本ビタミン学会第74回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Aldo-keto-reductase family 1, member c6 (Akr1c6)の機能解析.2022

    • Author(s)
      新村柚里香、土志田裕太、滝野有花、佐藤綾美、祖父江郁也、福井浩二、石神昭人
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] アスコルビン酸とその塩類の保存安定性について.2022

    • Author(s)
      田村元、滝野有花、石神昭人
    • Organizer
      第167回ビタミンC研究委員会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effects of estrogen on resistance training induced myosin heavy chain isoform shifts in female rat skeletal muscle.2022

    • Author(s)
      Yung-Li HUNG, Ayami SATO, Yuka TAKINO, Akihito ISHIGAMI, Shuichi MACHIDA
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] たばこ煙抽出液によるエピジェネティクスの変化に及ぼすビタミンCの影響.2022

    • Author(s)
      前田菜々子、佐藤綾美、滝野有花、石神昭人
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Epigenetic regulation by vitamin C in epidermal keratinization.2022

    • Author(s)
      Ayami SATO, Mio MATSUI, Nanako MAEDA, Yuka Takino, Akihito ISHIGAMI
    • Organizer
      日本基礎老化学会第45回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Effects of aging and sex differences on IGF-2 and myostatin gene expressions in rat skeletal muscle following resistance training.2022

    • Author(s)
      HUNG Yung-Li, SATO Ayami, TAKINO Yuka, ISHIGAMI Akihito, MACHIDA Shuichi
    • Organizer
      日本基礎老化学会第45回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Identification of Akr1c6 gene associated with SMP30 gene expression in mouse liver.2022

    • Author(s)
      Yurika NIIMURA, Yuta DOSHIDA, Fumiya SOBUE, Koji FUKUI, Toshiro AIGAKI, Sadahiro IWABUCHI, Shinichi HASHIMOTO, Jaewon LEE, Akihito ISHIGAMI
    • Organizer
      日本基礎老化学会第45回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] ビタミンCの新しい健康機能-新型コロナウイルスに対するCの効果を考える-2020

    • Author(s)
      石神昭人
    • Organizer
      第59回日本栄養・食糧学会近畿支部大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 皮膚におけるビタミンCの働き-皮膚でのエピジェネティクス研究も含めて-2020

    • Author(s)
      石神昭人
    • Organizer
      第38回日本美容皮膚科学会総会・学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] グルコノラクトナーゼ遺伝子破壊マウスを用いたビタミンCに関する諸問題へのアプローチ2020

    • Author(s)
      石神昭人
    • Organizer
      日本ビタミン学会第72回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 誰もが望む健康長寿の達成に欠かせないビタミンC2020

    • Author(s)
      石神昭人
    • Organizer
      2020年度ライフイノベーション研究所シンポジウム, 東洋大学ライフイノベーション研究所(Web開催)
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] タミンCの長期的な不足は寿命を短縮する2019

    • Author(s)
      石神昭人
    • Organizer
      第66回 日本栄養改善学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 老化研究における老年医学研究者からみた、技術者の貢献2019

    • Author(s)
      石神昭人
    • Organizer
      平成30年度日本実験動物技術者協会関東支部総会 第44回懇話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 健康寿命と食生活:健康寿命を延ばすためのビタミンC研究、基礎から臨床まで2019

    • Author(s)
      石神昭人
    • Organizer
      第46回東京成長ホルモン成長因子セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] ビタミンC合成不全マウスを用いた老化研究 -健康長寿を目指して-2019

    • Author(s)
      石神昭人
    • Organizer
      第1回 ビタミンC研究委員会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 漢方薬の抗酸化作用~ビタミンCの話題も交えて~2019

    • Author(s)
      石神昭人
    • Organizer
      日本東洋医学会茨城地方部会 第26回茨城県部会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] ビタミンCによる老化制御の可能性2019

    • Author(s)
      石神昭人
    • Organizer
      第31回日本老年学会総会(合同大会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Presentation] 新しいANCA関連血管炎自然発症モデルSICMの組織学的解析.2018

    • Author(s)
      濱野慶朋,伊藤 吹夕,鈴木章一,鈴木治,古浦美奈子,樋野興夫,湯村和子,石神昭人,亀岡洋祐,鈴木和男
    • Organizer
      日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07047
  • [Presentation] Vitamin C deficiency in skeletal muscle switches muscle fiber types from slow to fast2017

    • Author(s)
      Kondo Y, Takisawa S, Noda Y, Machida S, Aigaki T, Ishigami A.
    • Organizer
      ICFSR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Vitamin C deficiencr leads to skeletal muscle atrophy.2017

    • Author(s)
      Ishigami, A.
    • Organizer
      2017 Aging Seminar between Korea and Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] COPDモデルマウスを用いたビタミンC治療による肺胞修復メカニズムの遺伝子学的解析2017

    • Author(s)
      荒野直子、佐藤匡、烏谷惠子、Hario Baskoro、鈴木洋平、三井亜樹、児玉裕三、近藤嘉高、石神昭人、瀬山邦明、高橋和久
    • Organizer
      第57回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-26461199
  • [Presentation] Vitamin C Deficiency Leads to Skeletal Muscle Atrophy and Muscle Fiber Transformation2017

    • Author(s)
      Kondo Y, Takisawa S, Noda Y, Machida S, Aigaki T, Ishigami A.
    • Organizer
      IAGG 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Peptidylarginine deiminase 2 (PAD2) in mouse skeletal muscle.2017

    • Author(s)
      成田昂平、近藤嘉高、野田義博、町田修一、吉田雅幸、石神昭人
    • Organizer
      日本基礎老化学会第40回大会
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] アルツハイマー病診断薬の開発2017

    • Author(s)
      近藤嘉高、石神昭人
    • Organizer
      TOBIRA第6回研究交流フォーラム
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] 抗酸化ビタミンC, Eによるアンチエイジング2017

    • Author(s)
      石神昭人
    • Organizer
      日本ビタミン学会第69回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] 虚血モデルマウスにおける血管新生やミトコンドリアから見た運動の影響2017

    • Author(s)
      丸岡弘、金村尚彦、田中健一、林 弘之、善田聡史、小川明宏、石神昭人
    • Organizer
      第23回日本心臓リハビリテーション学術集会
    • Place of Presentation
      岐阜・長良川国際会議場
    • Year and Date
      2017-07-15
    • Data Source
      KAKENHI-PROJECT-26350623
  • [Presentation] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017

    • Author(s)
      Yohei Suzuki, Tadashi Sato, Masataka Sugimoto, Hario Baskoro, Keiko Karasutani, Aki Mitsui, Yuzo Kodama, Mitsuaki Sekiya, Akihito Ishigami, Kuniaki Seyama, Kazuhisa Takahashi
    • Organizer
      American Thoracic Society International Conference 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461199
  • [Presentation] SMP30/SOD1-double knockout mice manifest increased oxidative stress, hepatic steatosis, and premature death2017

    • Author(s)
      Ishigami A, Kasahara Y, Kondo Y.
    • Organizer
      Asian Society of Aging Research Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] ダブルノックアウトマウスは酸化ストレスが増加して脂肪肝を呈する2016

    • Author(s)
      近藤嘉高、増冨裕文、野田義博、小澤裕介、高橋経太、半田節子、丸山直記、清水孝彦、石神昭人
    • Organizer
      日本基礎老化学会第39回大会
    • Place of Presentation
      神奈川県伊勢原市民文化会館(小ホール), 伊勢原市, 神奈川県
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Citrullinated glial fibrillary acidic protein in Alzheimer’s diseased brains.2016

    • Author(s)
      Ishigami, A.
    • Organizer
      2016 Spring International Conference of the Korean Society for Gerontology and the 15th Korea-Japan Gerontologist Joint Meeting
    • Place of Presentation
      Hotel Laonzena, Convention Hall, Daegu, Korea
    • Year and Date
      2016-06-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] 経皮吸収したビタミンCによる紫外線(UVB)細胞傷害の抑制効果2016

    • Author(s)
      河島早紀、永田喜三郎、吉田雅幸、斉藤紀克、大澤肇、栗田克己、石神昭人
    • Organizer
      日本ビタミン学会第68回大会
    • Place of Presentation
      富山国際会議場, 富山市, 富山県
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] シトルリン化タンパク質を検出する臨床検査試薬の開発2016

    • Author(s)
      天野晶子、近藤嘉高、石神昭人
    • Organizer
      TOBIRA第5回研究交流フォーラム
    • Place of Presentation
      ソラシティカンファレンスセンター内ソラシティホール, 文京区, 東京都
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] Abnormal protein citrullination in Alzheimer’s disease.2016

    • Author(s)
      Ishigami, A.
    • Organizer
      11th Asia-Pacific Microscopy Conference (APMC11)
    • Place of Presentation
      Phuket Graceland Resort and Spa, Phuket, Thailand
    • Year and Date
      2016-05-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] ヒト培養表皮を用いた紫外線照射によるビタミンCの細胞傷害抑制効果2016

    • Author(s)
      河島早紀、永田喜三郎、佐藤安訓、吉田雅幸、石神昭人
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜, 横浜市, 神奈川県
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] 虚血モデルマウスにおける血管新生から見た運動やビタミンC摂取の影響2016

    • Author(s)
      丸岡弘、金村尚彦、国分貴徳、田中健一、村田健児、松本純一、善田聡史、石神昭人
    • Organizer
      第22回日本心臓リハビリテーション学術集会
    • Place of Presentation
      東京・東京国際フォーラム
    • Year and Date
      2016-07-16
    • Data Source
      KAKENHI-PROJECT-26350623
  • [Presentation] マウス骨格筋におけるペプチジルアルギニンデイミナーゼ2(PAD2)の生化学的解析2016

    • Author(s)
      成田昂平、近藤嘉高、増冨裕文、吉田雅幸、石神昭人
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜, 横浜市, 神奈川県
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] 新規に開発した抗化学修飾シトルリン化モノクローナル抗体を用いた脳におけるシトルリン化タンパク質の検出2016

    • Author(s)
      近藤嘉高、成田昂平、石神昭人
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜, 横浜市, 神奈川県
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] Dibutyryl-cAMP induced PAD expressions via PKA pathway in human astrocytoma U-251MG cells.2016

    • Author(s)
      Masutomi, H., Kawashima, S., Shimokado, K., Ishigami, A.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜, 横浜市, 神奈川県
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] マウス臓器、血漿中のα-トコフェロール量及び肝臓α-トコフェロール輸送タンパク質の加齢変化.2015

    • Author(s)
      高橋経太、下門顕太郎、河野 望、新井 洋由、石神昭人
    • Organizer
      日本ビタミン学会第67回大会
    • Place of Presentation
      奈良春日野国際フォーラム甍、奈良市、奈良
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Abnormal protein citrullination in Alzheimer’s disease.2015

    • Author(s)
      Ishigami, A.
    • Organizer
      The 10th IAGG Asia/Oceania Regional Congress (IAGG 2015)
    • Place of Presentation
      The International Convention and Exhibition Centre, Chiang Mai, Thailand
    • Year and Date
      2015-10-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] 虚血モデルマウスにおけるビタミンC摂取が血管新生や酸化ストレスにおよぼす影響2015

    • Author(s)
      丸岡弘、金村尚彦、木戸聡史、井上和久、松本純一、石神昭人、関貴之、金子幸輝
    • Organizer
      第50 回日本理学療法学術大会
    • Place of Presentation
      東京・東京国際フォーラム
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26350623
  • [Presentation] Senescence marker protein-30/Superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis.2015

    • Author(s)
      Ishigami, A., Kondo, Y., Masutomi, H., Noda, Y., Ozawa, Y., Takahashi, K., Maruyama, N., Shimizu, T.
    • Organizer
      The 10th IAGG Asia/Oceania Regional Congress (IAGG 2015)
    • Place of Presentation
      The International Convention and Exhibition Centre, Chiang Mai, Thailand
    • Year and Date
      2015-10-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Vitamin C study using SMP30/GNL knockout mice.2015

    • Author(s)
      Ishigami, A.
    • Organizer
      ACN2015
    • Place of Presentation
      PACIFICO Yokohama, Yokohama, Japan
    • Year and Date
      2015-05-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] マウスの様々な臓器、血漿中のα-トコフェロール量及び肝臓でのα-トコフェロール輸送タンパク質(α-TTP)の加齢変化.2015

    • Author(s)
      石神昭人、高橋経太、河野望、新井洋由
    • Organizer
      第18回Vitamin E Update Forum
    • Place of Presentation
      如水会館、千代田区、東京
    • Year and Date
      2015-08-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] Abnormal accumulation of citrullinated proteins in Alzheimer’s disease.2015

    • Author(s)
      Ishigami, A.
    • Organizer
      The 19th Thai Neuroscience Society Conference 2015
    • Place of Presentation
      Mahidol University, Salaya, Nakhonpathom, Thailand
    • Year and Date
      2015-10-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] 胎児の発生や小児の成長におけるビタミンCの必要性.2015

    • Author(s)
      石神昭人
    • Organizer
      第39回日本産科婦人科栄養・代謝研究会
    • Place of Presentation
      東京医科歯科大学、文京区、東京
    • Year and Date
      2015-08-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04505
  • [Presentation] ヒトアストロサイトーマ細胞株U-251MG細胞でのcAMPによるPADs誘導、及びシトルリン化タンパク質の増加.2015

    • Author(s)
      増冨裕文、下門顕太郎、石神昭人
    • Organizer
      第38回日本基礎老化学会大会
    • Place of Presentation
      パシフィコ横浜、横浜、神奈川
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] シトルリン化タンパク質特異的モノクローナル抗体の確立.2015

    • Author(s)
      加賀美弥生、増冨裕文、丸山直記、石神昭人
    • Organizer
      第38回日本基礎老化学会大会
    • Place of Presentation
      パシフィコ横浜、横浜、神奈川
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] Detection of citrullinated proteins in the postmortem brain from wild-type and PAD2-knockout mice using newly developed anti-modified citrulline monoclonal antibodies.2015

    • Author(s)
      Kagami, Y. Masutomi, H., Choi, E.K., Kim, Y.S., Maruyama, N., Ishigami, A.
    • Organizer
      The 10th IAGG Asia/Oceania Regional Congress (IAGG 2015)
    • Place of Presentation
      The International Convention and Exhibition Centre, Chiang Mai, Thailand
    • Year and Date
      2015-10-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15104
  • [Presentation] ビタミンCと老化2014

    • Author(s)
      石神昭人
    • Organizer
      第16回 抗加齢歯科医学研究会主催講習会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 女性の高齢期におけるビタミンCの必要性2014

    • Author(s)
      石神昭人
    • Organizer
      第29回日本女性医学学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 脂質代謝異常と加齢指標タンパク質30(SMP30)2014

    • Author(s)
      石神昭人、近藤嘉高
    • Organizer
      第14回日本抗加齢医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンCで健康長寿、老化のスピードを遅らせる2014

    • Author(s)
      石神昭人
    • Organizer
      日本ビタミン学会市民公開講座
    • Place of Presentation
      松山
    • Year and Date
      2014-11-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] PADI4測定系の確立と臨床応用2014

    • Author(s)
      石神昭人
    • Organizer
      第58回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] ビタミンCトランスポーター研究の現状と展望2014

    • Author(s)
      石神昭人
    • Organizer
      日本ビタミン学会第66回大会
    • Place of Presentation
      姫路
    • Year and Date
      2014-06-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ヒト皮膚線維芽細胞での1型コラーゲン遺伝子発現に及ぼすアスコルビン酸の効果.2013

    • Author(s)
      岸本祐樹、下門顕太郎、丸山直記、石神昭人
    • Organizer
      日本ビタミン学会第65回大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Senescence Marker Protein-30欠乏は尿細管間質線維化により糖尿病腎症進展に関与する2013

    • Author(s)
      岡田博史、千丸貴史、石神昭人、近藤嘉高、尾林博、浅野麻衣、山崎真裕、福井道明、長谷川剛二、中村直登
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] ヒト皮膚線維芽細胞におけるビタミンC、コラーゲンペプチド、CoQ10、ナイアシンのコラーゲン及びビタミンC輸送体遺伝子発現に及ぼす効果.2013

    • Author(s)
      岸本祐樹、飯島みゆき、泉澤勝弘、阿部皓一、石神昭人
    • Organizer
      第67回日本栄養・食糧学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Vitamin C and aging. Presidential Symposium “Nutritional Intervention in Ageing”2013

    • Author(s)
      Ishigami, A.
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics (IAGG 2013)
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Peptidylarginine deiminase 2-mediat ed protein citrullinati on in prion disease.2013

    • Author(s)
      Kim, H.J., Jang, B., Jin, J.K., Jeon, Y.C., Ishigami, A., Maruyama, N., Carp, R.I., Kim, Y.S., Choi, E.K.
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics (IAGG 2013)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] Relationship between plasma carotenoid levels and physical performance among Japanese elderly.2013

    • Author(s)
      Saito, K., Ishigami, A., Kishimoto, Y., Maruyama, M., Oubuchi, S., Kim, M.
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics (IAGG 2013)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ペントースリン酸副経路で働くヒトおよびマウスにおけるグルコン酸キナーゼの同定.2013

    • Author(s)
      近藤嘉高、半田節子、丸山直記、石神昭人
    • Organizer
      第86回日本生化学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] SMP30/GNLノックアウトマウスを用いたアスコルビン酸摂取量の違いによる寿命への影響.2013

    • Author(s)
      天野晶子、岸本祐樹、相垣敏郎、丸山直記、石神昭人
    • Organizer
      第36回日本基礎老化学会大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 長期的なアスコルビン酸欠乏が肝臓の遺伝子発現及び脂質代謝に及ぼす影響.2013

    • Author(s)
      高橋経太、岸本祐樹、小西智一、下門顕太郎、丸山直記、石神昭人
    • Organizer
      日本ビタミン学会第65回大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Senescence marker protein-30 deficiency accelerates diabetic renal injury through tubulointerstitial fibrosis in a mouse model of type 1 diabetes2013

    • Author(s)
      Okada H, Senmaru T, Kondo Y, Ishigami A, Obayashi H, Asano M, Yamazaki M, Fukui M, Hasegawa G, Nakamura N
    • Organizer
      73th annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] SMP30を欠損したLeprdb/dbマウスはsmall dense LDLが高く脂肪肝を呈する.2013

    • Author(s)
      近藤嘉高、長谷川剛二、千丸貴史、福井道明、中村直登、丸山直記、尾林博、石神昭人
    • Organizer
      第36回 日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンCによる慢性閉塞性肺疾患(COPD)治療効果の検討.2013

    • Author(s)
      石神昭人
    • Organizer
      第142回ビタミンC研究委員会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 酸化ストレスとビタミンC.2013

    • Author(s)
      石神昭人
    • Organizer
      健康医科学産業協議会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 胎児の発生や小児の成長、高齢期におけるビタミンCの必要性.2013

    • Author(s)
      石神昭人
    • Organizer
      日本ビタミン学会第65回大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンCの不足が胎児の発生や成長、老化や老年病に及ぼす影響.2013

    • Author(s)
      石神昭人
    • Organizer
      第30回日本微量栄養素学会学術集会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Age-related changes of peptidylarginine deiminase 2 in the mouse brain.2013

    • Author(s)
      Kagami, Y., Shimada, N., Handa, S., Choi, E.K., Kim, Y.S., Ito, H., Maruyama, N., Ishigami, A.
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics (IAGG 2013)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] Age-related change of protein degradation in mouse liver parenchymal cells.2013

    • Author(s)
      Kishimoto, Y., Amano, A., Maruyama, N., Ishigami, A.
    • Organizer
      The American Aging Association's 42nd Annual Meeting
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 高用量ビタミンC の長期摂取は加齢に伴う胸腺の萎縮や免疫細胞数の低下を抑制する.2013

    • Author(s)
      内尾隆正、広瀬義隆、室崎伸二、山本佳弘、石神昭人
    • Organizer
      第35 回日本臨床栄養学会総会・第34回日本臨床栄養協会総会 第11回大連合大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Senescence marker protein-30 deficiency accelerates diabetic renal injury through tubulointerstitial fibrosis in a mouse model of type 1 diabetes2013

    • Author(s)
      Okada H, Senmaru T, Kondo Y, Ishigami A, Obayashi H, Asano M, Yamazaki M, Fukui M, Hasegawa G, Nakamura N
    • Organizer
      73th annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] 肝臓の遺伝子発現及び脂質代謝に及ぼすアスコルビン酸欠乏の影響2012

    • Author(s)
      石神昭人、高橋経太
    • Organizer
      第139回ビタミンC研究委員会
    • Place of Presentation
      奈良
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンC欠乏は糖尿病性腎症の尿細管病変の発症に関与する:SMP30 KOマウスを用いての検討2012

    • Author(s)
      岡田博史、千丸貴史、石神昭人、近藤嘉高、尾林博、浅野麻衣、山崎真裕、福井道明、長谷川剛二、中村直登
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] .ビタミンC欠乏は糖尿病性腎症の尿細管病変の発症に関与する:SMP30 KOマウスを用いての検討2012

    • Author(s)
      岡田博史、千丸貴史、石神昭人、近藤嘉高、尾林博、浅野麻衣、山崎真裕、福井道明、長谷川剛二、中村直登
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] タンパク質分解系の加齢変化2012

    • Author(s)
      石神昭人、丸山直記
    • Organizer
      第66回日本栄養・食糧学会大会
    • Place of Presentation
      仙台(招待講演)
    • Year and Date
      2012-05-20
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] Differential effect of vitamin C deficiency on the pathogenesis of diabetic nephropathy2012

    • Author(s)
      Okada H, Senmaru T, Kondo Y, Ishigami A, Obayashi H, Asano M, Yamazaki M, Fukui M, Hasegawa G, Nakamura N
    • Organizer
      72th annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] ビタミンCとAnti-aging2012

    • Author(s)
      石神昭人
    • Organizer
      第35回日本美容外科学会総会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンCの抗老化作用2012

    • Author(s)
      石神昭人
    • Organizer
      近畿大学サイエンスフォーラム
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ビタミンCと老化、老化関連疾患2011

    • Author(s)
      石神昭人
    • Organizer
      日本基礎老化学会
    • Place of Presentation
      千葉
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] ビタミンCの体内動態とその抗酸化能力2011

    • Author(s)
      石神昭人
    • Organizer
      第65回日本栄養・食糧学会大会シンポジウム「微量栄養素と生体機能との相互作用」
    • Place of Presentation
      東京
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] ビタミンC不足と寿命との関係2011

    • Author(s)
      石神昭人
    • Organizer
      平成23年度「ビタミンの日」記念講演会,日本バイオファクター協会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] Smp30/Sod1ダブルノックアウトマウスにおける肝臓の組織学的解析2011

    • Author(s)
      岩間水輝、野田義博、清水孝彦、近藤嘉高、丸山直記、石神昭人
    • Organizer
      日本ビタミン学会第63回大会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] 特別シンポジウム「これからの基礎老化研究を考える」2011

    • Author(s)
      石神昭人
    • Organizer
      第34回日本基礎老化学会大
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] アルツハイマー病治療薬を指向したアミロイドベータ凝集阻害剤の開発:アリールベンゾフラン誘導体2011

    • Author(s)
      鈴木英治、今井雅之、松山明弘、奥野友哉梨、中越雅道、石神昭人、氷川英正、横山祐作
    • Organizer
      第131回日本薬学会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Presentation] ビタミンC欠乏がカテコールアミン生合成系に及ぼす影響2011

    • Author(s)
      天野晶子、角田誠、相垣敏郎、丸山直記、石神昭人
    • Organizer
      日本ビタミン学会第63回大会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] ビタミンC不足と寿命との関係2011

    • Author(s)
      石神昭人
    • Organizer
      日本バイオファクター協会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] Insulin Release from Pancreatic Islet in Vitamin C-Deficient Senescence Marker Protein-30/Gluconolactonase Knockout Mice2011

    • Author(s)
      Senmaru T, Hasegawa G, Ishigami A, Kondo Y, Okada H, Asano M, Yamazaki M, Fukui M, Nakamura N
    • Organizer
      71th annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      SanDiego
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] ヒトSMP30のX線結晶構造解析2011

    • Author(s)
      相澤真悟、千田美紀、相垣敏郎、丸山直記、石神昭人、千田俊哉
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] ビタミンCのインスリン分泌における役割:SMP30/GNLノックアウトマウスを用いての検討2011

    • Author(s)
      千丸貴史、長谷川剛二、石神昭人、近藤嘉高、尾林博、岡田博史、浅野麻衣、山崎真裕、福井道明、中村直登
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] Insulin Release from Pancreatic Islet in Vitamin C-Deficient Senescence Marker Protein-30/Gluconolactonase Knockout Mice2011

    • Author(s)
      Senmaru T, Hasegawa G, Ishigami A, Kondo Y, Okada H, Asano M, Yamazaki M, Fukui M, Nakamura N
    • Organizer
      71th annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      SanDiego, USA
    • Data Source
      KAKENHI-PROJECT-23591317
  • [Presentation] ビタミンCの体内動態とその抗酸化能力2011

    • Author(s)
      石神昭人
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] Deficiency of senescence marker protein 30 exacerbates angiotensin II-induced cardiac remodeling2011

    • Author(s)
      Misaka T, Suzuki S, Miyata M, Kobayashi A, Saitoh S, Ishigami A, Takeishi Y
    • Organizer
      Congress of the European Society of Cardiology
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-21590935
  • [Presentation] ビタミンC欠乏マウスにおける活性酸素種は増加する2011

    • Author(s)
      近藤嘉高、加賀美弥生、半田節子、石神昭人、丸山直記
    • Organizer
      第65回日本栄養・食糧学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] Senescence Marker Protein-30 deficient mice exhibit impaired insulin secretion due to dysfunction of the distal portion of secretion pathway.2010

    • Author(s)
      千丸貴史, 長谷川剛二, 石神昭人, 近藤嘉高, 田中武兵, 山崎真裕, 福井道明, 中村直登
    • Organizer
      70^<th> annual meeting and scientific sessions of American Diabetes Association.
    • Place of Presentation
      Orland, USA.
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] Senescence Marker Protein-30 deficient mice exhibit impaired acute insulin secretion due to dysfunction of the distal portion of secretion pathway.2010

    • Author(s)
      千丸貴史, 長谷川剛二, 石神昭人, 近藤嘉高, 田中武兵, 山崎真裕, 福井道明, 中村直登
    • Organizer
      8^<th> international diabetes federation western pacific region congress.
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] Senescence Marker protein-30 (SMP30)の減少は早期インスリン分泌を障害する2010

    • Author(s)
      千丸貴史、長谷川剛二、石神昭人、近藤嘉高、田中武兵、山崎真裕、福井道明、中村直登
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] Senescence Marker Protein-30 deletion worsens glucose tolerance through impairment of acute insulin secretion.2010

    • Author(s)
      長谷川剛二, 石神昭人, 近藤嘉高, 田中武兵, 千丸貴史, 山崎真裕, 福井道明, 中村直登
    • Organizer
      14^<th> international congress of endocrinology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] 慢性閉塞性肺疾患(COPD)とビタミンC2010

    • Author(s)
      石神昭人
    • Place of Presentation
      東京
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] ストレスによるマウス血漿総抗酸化能、抗酸化物質濃度の変化2010

    • Author(s)
      人見嘉哲、辻本藤太郎、石神昭人、近藤嘉高、神林康弘、弘田量二、日比野由利、柴田亜樹、中村裕之
    • Organizer
      第9回分子予防環境医学研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Presentation] 慢性閉塞性肺疾患(COPD)とビタミンC2010

    • Author(s)
      石神昭人
    • Organizer
      抗加齢医学フォーラム
    • Place of Presentation
      目黒雅叙園(東京都)
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] SMP30/GNL遺伝子破壊マウスを用いたビタミンCと老化、疾患研究2009

    • Author(s)
      石神昭人
    • Organizer
      第56回日本実験動物学会総会シンポジウムモデルマウスを用いた老化への分子遺伝学的アプローチ
    • Place of Presentation
      大宮
    • Year and Date
      2009-05-16
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] 関節リウマチにおける血漿ペプチジルアルギニンデイミナーゼ4(PAD4)及び抗PAD4抗体2009

    • Author(s)
      木村直樹、杉原毅彦、石神昭人
    • Organizer
      第53回日本リウマチ学会総会・学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590392
  • [Presentation] 加齢指標蛋白質SMP30の糖代謝における役割2009

    • Author(s)
      千丸貴史、長谷川剛二、石神昭人、近藤嘉高、山崎真裕、田中武兵、浅野麻衣、福井道明、中村直登
    • Organizer
      第82回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] SMP30/GNL遺伝子破壊マウスを用いたビタミンCと老化、疾患研究2009

    • Author(s)
      石神昭人
    • Organizer
      第56回日本実験物学会総会
    • Place of Presentation
      大宮ソニックシティー(埼玉)
    • Year and Date
      2009-05-16
    • Data Source
      KAKENHI-PROJECT-21590974
  • [Presentation] 弱酸性域に至適pHを持つベータガラクトシダーゼ活性を用いた老化度測定法の開発2008

    • Author(s)
      五味恵子、島田信子、福田貢、榊原達哉、半田節子、高橋良哉、丸山直記、石神昭人
    • Organizer
      第48回日本臨床化学会
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 生体内におけるカルニチン合成へのビタミンCの関与2008

    • Author(s)
      古澤元、佐藤安訓、高橋良哉、石神昭人
    • Organizer
      第128回日本薬学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] カルニチン合成系へのビタミンCの関与2008

    • Author(s)
      石神昭人、古澤元、佐藤安訓、井内陽子、錦見盛光、村田晃、半田節子、島田信子、福田貢、高橋良哉
    • Organizer
      第60回日本ビタミン学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 脳におけるビタミンCの活性酸素消去能の検討2008

    • Author(s)
      近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
    • Organizer
      第60回日本ビタミン学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] マウス肝臓におけるSMP30/GNLの組織学的加齢変化2008

    • Author(s)
      半田節子、島田信子、天野晶子、福田貢、近藤嘉高、丸山直記、石神昭人
    • Organizer
      第31回日本分子生物学会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Presentation] 脳におけるビタミンCの活性酸素消去能の解析2008

    • Author(s)
      近藤嘉高、佐々木徹、佐藤安訓、天野晶子、岩間水輝、半田節子、島田信子、福田貢、丸山直記、石神昭人
    • Organizer
      第31回日本基礎老化学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] マウス肝臓におけるSMP30/GNLの組織学的加齢変化2008

    • Author(s)
      半田節子、島田信子、天野晶子、福田貢、近藤嘉高、丸山直記、石神昭人
    • Organizer
      第31回日本分子生物学会・第81回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] アルツハイマー病早期臨床検査試薬としてのシトルリン化GFAPサンドイッチELISA法の確立2008

    • Author(s)
      石神昭人、半田節子、島田信子、丸山直記、真鍋幸子、高橋良哉、内田好昭
    • Organizer
      第48回日本臨床化学会
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 未病における肺疾患とビタミンCの関係2008

    • Author(s)
      石神昭人
    • Organizer
      第15回日本未病システム学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミンC生合成経路で働く酵素グルコノラクトナーゼ (SMP30/GNL)の加齢変化2008

    • Author(s)
      天野晶子、近藤嘉高、岩間水輝、佐藤安訓、半田節子、相垣敏郎、石神昭人
    • Organizer
      第62回日本栄養・食糧学会
    • Place of Presentation
      埼玉
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Presentation] Role of senescence marker protein-30 in glucose homeostasis.2008

    • Author(s)
      Hasegawa G, Ishigami A, Kondo Y, Kadono M, Asano M, Tanaka M, Hosoda H, Yamasaki M, Fukui M, Nakamura N
    • Organizer
      68^<th> annual meeting and scientific sessions of American Diabetes Association
    • Place of Presentation
      San Francisco, USA.
    • Data Source
      KAKENHI-PROJECT-20591066
  • [Presentation] 慢性閉塞性肺疾患(COPD)モデルマウスの開発.2008

    • Author(s)
      石神 昭人, 他
    • Organizer
      第128回日本薬学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミン C 欠乏による SVCT1 および SVCT2 発現調節の検討2008

    • Author(s)
      天野晶子、島田信子、岩間水輝、福田貢、半田節子、丸山直記、相垣敏郎、石神昭人
    • Organizer
      第60回日本ビタミン学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 生体内におけるカルニチン合成へのビタミンCの関与2008

    • Author(s)
      古澤元、佐藤安訓、高橋良哉、石神昭人
    • Organizer
      第128回日本薬学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Presentation] ビタミンCの不足は慢性閉塞性肺疾患(COPD)発症リスクを高める.2007

    • Author(s)
      石神 昭人, 他
    • Organizer
      第61回日本栄養・食糧学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] デジタル老化説-マウス肝臓におけるSMP30の加齢変化-2007

    • Author(s)
      半田節子、久保幸穂、福田貢、丸山直記、石神昭人
    • Organizer
      第30回日本基礎老化学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19580156
  • [Presentation] デジタル老化説-マウス肝臓におけるSMP30の加齢変化-2007

    • Author(s)
      半田節子、久保幸穂、福田貢、丸山直記、石神昭人
    • Organizer
      第30回日本基礎老化学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミンCの不足は慢性閉塞性肺疾患(COPD)発症リスクを高める2007

    • Author(s)
      石神昭人、佐藤匡、佐藤安訓、近藤嘉高、瀬山邦明、丸山直記
    • Organizer
      第61回日本栄養・食糧学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 細胞老化関連遺伝子TARSH/Abi3bpの発現量低下と発癌の機能的関連2007

    • Author(s)
      上川奈都子、島田信子、石神昭人、杉本昌隆、丸山直記、丸山光生
    • Organizer
      第30回日本基礎老化学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める2007

    • Author(s)
      石神昭人、佐藤匡、佐藤安訓、近藤嘉高、瀬山邦明、丸山直記
    • Organizer
      第59回日本ビタミン学会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミンC不足は慢性閉塞性肺疾患の発症リスクを高める.2007

    • Author(s)
      石神 昭人, 他
    • Organizer
      第59回日本ビタミン学会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] 脳におけるペプチジルアルギニンデイミナーゼ2(PAD2)の加齢変化2007

    • Author(s)
      島田信子、朝倉(遊長)由希、半田節子、町田武生、石神昭人
    • Organizer
      第30回日本基礎老化学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] ビタミンC不足は老化を加速2007

    • Author(s)
      石神昭人、佐藤安訓、近藤嘉高、古澤元、天野晶子、島田信子、福田貢、半田節子、久保幸穂、丸山直記
    • Organizer
      第127回日本薬学会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-19590925
  • [Presentation] Increased citrullinated proteins in the brains of scrarpie-infected mice.2006

    • Author(s)
      Jang, B., Kim, E., Choi, JK., Jin, JK., Ishigami, A., Choi, EK.
    • Organizer
      2006 Conference of the Korea Society for Gerontology and Institute of Pharmaceutical Science
    • Place of Presentation
      Kangwon National University, Chuncheon, Korea
    • Year and Date
      2006-06-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590355
  • [Presentation] ヒトグリオーマ細胞株U-251MG細胞でのPAD2誘導に伴うシトルリン化タンパク質の増加

    • Author(s)
      増冨裕文、下門顕太郎、石神昭人
    • Organizer
      第37回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] シトルリン化タンパク質特異的モノクローナル抗体の作製と特異性の解析

    • Author(s)
      加賀美弥生、丸山直記、石神昭人
    • Organizer
      第37回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] ビタミンC 生合成不全マウスにおける社会的環境の違いによるストレス応答の差異

    • Author(s)
      小泉美和子、近藤嘉高、伊坂亜友美、石神昭人、鈴木恵美子
    • Organizer
      第68回日本栄養・食糧学会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-30 – 2014-06-01
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] マウス肝臓における加齢指標タンパク質30(SMP30)の組織学的加齢変化

    • Author(s)
      増冨裕文、下門顕太郎、丸山直記、石神昭人
    • Organizer
      第37回日本基礎老化学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-06-26 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] 社会的環境において惹起される抑うつ様行動に対するビタミンCの働き

    • Author(s)
      小泉美和子、近藤嘉高、伊坂亜友美、石神昭人、鈴木恵美子
    • Organizer
      日本ビタミン学会第66回大会
    • Place of Presentation
      姫路
    • Year and Date
      2014-06-13 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-24380073
  • [Presentation] ヒトグリオーマ細胞株U-251MG細胞におけるcAMPによるPAD2の誘導

    • Author(s)
      増冨裕文、下門顕太郎、丸山直記、石神昭人
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24659169
  • [Presentation] アミロイドβ凝集阻害・繊維溶解作用をもつジアリルベンゾフラン誘導体

    • Author(s)
      鈴木英治,矢島聖也,山口勇樹, 佐々木雄大,中越雅道,石神昭人,津吹政可,横山祐作
    • Organizer
      第30回メディシナルケミストリーシンポジウム
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-24590147
  • [Presentation] シトルリン化タンパク質特異的モノクローナル抗体の作製と特異性の解析

    • Author(s)
      加賀美弥生,丸山直記,石神昭人
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26460448
  • []

  • []

  • 1.  HANDA Setsuko (30360697)
    # of Collaborated Projects: 6 results
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  • 2.  MARUYAMA Naoki (00115940)
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  • 3.  KUBO Sachiho (00280769)
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  • 4.  SENSHU Tatsuo (60072998)
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  • 5.  AKIYAMA Kyoichi (10110024)
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  • 6.  HASEGAWA Goji (00295643)
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  • 7.  TAKEISHI Yasuchika (40272067)
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  • 8.  OHSAWA Takako (20073017)
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  • 9.  ASAGA Hiroaki (80231877)
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  • 10.  橋本 真一 (00313099)
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  • 11.  SHIMADA Nobuko (60158962)
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  • 12.  SAITOH Shu-ichi (20274962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  FUKUI Michiaki (30247829)
    # of Collaborated Projects: 1 results
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  • 14.  YAMAZAKI Masahiro (50309134)
    # of Collaborated Projects: 1 results
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  • 15.  SUZUKI Hideharu (40187753)
    # of Collaborated Projects: 1 results
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  • 16.  OIKAWA Masayoshi (30457775)
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  • 17.  SUZUKI Satoshi (60536944)
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  • 18.  Sugihara Takahiko (00716441)
    # of Collaborated Projects: 1 results
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  • 19.  Maruoka Hiroshi (80325985)
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  • 20.  Kanemura Naohiko (20379895)
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    # of Collaborated Products: 4 results
  • 21.  Tanaka Kenichi (20281313)
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    # of Collaborated Products: 2 results
  • 22.  Sato Tadashi (10596993)
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  • 23.  Hamano Yoshitomo (10281354)
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  • 24.  Chiba Takuya (40336152)
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  • 25.  加賀美 弥生 (80557661)
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  • 26.  南木 敏宏 (00282749)
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  • 27.  針谷 正祥 (20238207)
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  • 28.  石崎 達郎 (30246045)
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  • 29.  田中 雅嗣 (60155166)
    # of Collaborated Projects: 1 results
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  • 30.  瀬山 邦明 (10226681)
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  • 31.  高橋 史行 (70327823)
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  • 32.  小浦 美奈子 (10370967)
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  • 33.  伊藤 吹夕 (20415079)
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  • 34.  鈴木 治 (70235935)
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  • 35.  町田 修一 (40421226)
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  • 36.  川西 範明 (00706533)
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  • 37.  近藤 嘉高 (20507397)
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  • 38.  Matumoto Jyunichi
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  • 39.  SUZUKI Yohei
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  • 40.  MITSUI Aki
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  • 41.  RENNARD Stephen I.
    # of Collaborated Projects: 1 results
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  • 42.  SUGIMOTO Masataka
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  • 43.  SUGIMOTO Kazushi
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  • 44.  HASHIMOTO Kohshi
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  • 45.  OHMURA Koichiro
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  • 46.  NAKABO Shuichiro
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  • 47.  KINOSHITA Manabu
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  • 48.  SAITOH Daizoh
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  • 49.  NADANAKA Satomi
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  • 50.  土志田 裕太
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  • 51.  小林 典裕
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  • 52.  永田 喜三郎
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  • 53.  宮原 大貴
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  • 54.  佐藤 綾美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 55.  小林 芳郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  増田 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  西 宏起
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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