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Saigo Kazumasa  西郷 和真

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… Alternative Names

西郷 和真  サイゴウ カズマサ

SAIGOH Kazumasa  西郷 和真

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Researcher Number 50319688
Other IDs
Affiliation (Current) 2025: 近畿大学, 大学病院, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 近畿大学, 大学病院, 教授
2015 – 2018: 近畿大学, 理工学部, 准教授
2010 – 2015: 近畿大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related / Environmental physiology (including Physical medicine and Nutritional physiology)
Except Principal Investigator
Neurology / Medical pharmacy / Environmental physiology(including physical medicine and nutritional physiology)
Keywords
Principal Investigator
レビ-小体型認知症 / 酸化型 DJ-1 / 鑑別 / バイオマーカー / パーキンソン症候群 / パーキンソン病 / アルツハイマー型認知症 / レビー小体型認知症 / 多系統萎縮症(MSA) / 進行性核上性麻痺(PSP) … More / パーキンソン病(PD) / レビ-小体型認知症(DLB) / アルツハイマー型認知症(AD)を / 血液バイオマーカー / 認知症 / DJ-1 / 糖鎖転移酵素遺伝子群 / α-2,8-sialyltransferase8 / 視交叉上核 / ST8Sia II / α-2,8-sialyltransferase 8 / 視交叉上核(SCN) / ST8Sia VI / ST8SiaII / sialyltransferase8 / 概日リスム / 視交叉上核 (SCN) / シアル酸転移酵素 / ST8SiaVI 遺伝子 / 糖鎖遺伝子 / 概日リズム / 睡眠障害 / 睡眠・覚醒 … More
Except Principal Investigator
脳神経疾患 / 自己抗体 / ギラン・バレー症候群 / ガングリオシド / 糖脂質 / 糖鎖 / iPS細胞 / 抗がん剤 / 治療薬開発 / ALS / ERBB4 / 筋萎縮性側索硬化症 / リン酸化阻害剤 / 免疫学 / 神経科学 / 脳・神経 / 脳脊髄炎 / 末梢神経障害 / 免疫性神経疾患 / 酸化DJ-1 / ドパミン神経 / ELISA / 早期診断 / モノクローナル抗体 / バイオマーカー / DJ-1 / 酸化ストレス / パーキンソン病 / 発光イメージング / Sik3 ノックアウトマウス / タンパク質分解 / アストロサイト / リン酸化 / PER2 / SIK3 / 時計タンパク質 / ノックアウトマウス / 代謝 / リン酸化酵素 / 概日リズム / ミエリン / シアル酸 / 脱髄 / 硫酸化糖脂質 / 神経疾患 / 自己免疫 Less
  • Research Projects

    (7 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (19 People)
  •  The Blood Diagnostic Markers in Dementia with Lewy BodiesPrincipal Investigator

    • Principal Investigator
      西郷 和真
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Kindai University
  •  Clarification of pathomechanism via amyotrophic lateral sclerosis-causing ERBB4 and effectiveness of anti-cancer medicine.

    • Principal Investigator
      HIRANO Makito
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kindai University
  •  Analysis of target antigens and pathogenetic mechanisms of neuroimmunological diseases using glycoarray

    • Principal Investigator
      KUSUNOKI Susumu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kindai University
  •  A novel kinase signaling involved in the dual regulation of behavior and metabolism

    • Principal Investigator
      Hayasaka Naoto
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Nagoya University
      Yamaguchi University
  •  Development of diagnosis and treatment of Parkinson disease at early stage using novel biomarker oxidized DJ-1

    • Principal Investigator
      Yoshiro Saito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Doshisha University
  •  Analysis of negative regulators of B lymphocyte responses to glycoconjugates in neuroimmunological diseases

    • Principal Investigator
      KUSUNOKI Susumu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kinki University
  •  The glycosyltransferase gene cluster associated with the circadian rhythm expression change in the suprachiasmatic nucleusPrincipal Investigator

    • Principal Investigator
      SAIGOH Kazumasa
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Kinki University

All 2023 2022 2019 2018 2017 2016 2014 2013 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Memantine administration prevented chorea movement in Huntington’s disease: a case report2023

    • Author(s)
      Saigoh Kazumasa、Hirano Makito、Mitsui Yoshiyuki、Oda Itsuki、Ikegawa Atsuko、Samukawa Makoto、Yoshikawa Keisuke、Yamagishi Yuko、Kusunoki Susumu、Nagai Yoshitaka
    • Journal Title

      Journal of Medical Case Reports

      Volume: 17 Pages: 4311-4315

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07547
  • [Journal Article] CANVAS-related RFC1 mutations in patients with immune-mediated neuropathy2023

    • Author(s)
      Hirano Makito、Kuwahara Motoi、Yamagishi Yuko、Samukawa Makoto、Fujii Kanako、Yamashita Shoko、Ando Masahiro、Oka Nobuyuki、Nagano Mamoru、Matsui Taro、Takeuchi Toshihide、Saigoh Kazumasa、Kusunoki Susumu、Takashima Hiroshi、Nagai Yoshitaka
    • Journal Title

      Scientific Reports

      Volume: 13 Pages: 178011-178016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07547
  • [Journal Article] PSP-Phenotype in SCA8: Case Report and Systemic Review2019

    • Author(s)
      Samukawa M, Hirano M, Saigoh K, Kawai S, Hamada Y, Takahashi D, Nakamura Y, Kusunoki S.
    • Journal Title

      Cerebellum

      Volume: 18 Issue: 1 Pages: 76-84

    • DOI

      10.1007/s12311-018-0955-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Journal Article] Noncoding repeat expansions for ALS in Japan are associated with the ATXN8OS gene.2018

    • Author(s)
      Hirano M, Samukawa M, Isono C, Saigoh K, Nakamura Y, Kusunoki S.
    • Journal Title

      Neurol Genet

      Volume: 4 Issue: 4

    • DOI

      10.1212/nxg.0000000000000252

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Journal Article] Diagnosis of Parkinson's disease and the level of oxidized DJ-1 protein.2018

    • Author(s)
      Yamagishi Y, Saigoh K, Saito Y, Ogawa I, Mitsui Y, Hamada Y, Samukawa M, Suzuki H, Kuwahara M, Hirano M, Noguchi N, Kusunoki S.
    • Journal Title

      Neurosci Res.

      Volume: なし Pages: 58-62

    • DOI

      10.1016/j.neures.2017.06.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09705, KAKENHI-PROJECT-17H03821
  • [Journal Article] The novel de novo mutation of KIF1A gene as the cause for Spastic paraplegia 30 in a Japanese case.2018

    • Author(s)
      Yoshikawa K, Kuwahara M, Saigoh K, Ishiura H, Yamagishi Y, Hamano Y, Samukawa M, Suzuki H, Hirano M, Mitsui Y, Tsuji S, Kusunoki S.
    • Journal Title

      eNeurologicalSci

      Volume: 2018 Pages: 34-37

    • DOI

      10.1016/j.ensci.2018.11.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Journal Article] Novel mutation in the SOD1 gene in a patient with early-onset, rapidly progressive amyotrophic lateral sclerosis2017

    • Author(s)
      Okazaki Masahiro、Suzuki Hidekazu、Takahashi Yuji、Ishiura Hiroyuki、Goto Jun、Hirano Makito、Saigoh Kazumasa、Nakamura Yusaku、Naruse Hiroya、Mitsui Jun、Tsuji Shoji、Kusunoki Susumu
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 5 Issue: 6 Pages: 189-191

    • DOI

      10.1111/ncn3.12153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Journal Article] Time Course of Radiological Imaging and Variable Interindividual Symptoms in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Associated with p.Arg487His Mutation in the VCP Gene2017

    • Author(s)
      Hirano Makito、Yamagishi Yuko、Yanagimoto Satoshi、Saigoh Kazumasa?、Nakamura Yusaku、Kusunoki Susumu
    • Journal Title

      European Neurology

      Volume: 78 Issue: 1-2 Pages: 78-83

    • DOI

      10.1159/000478906

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Journal Article] Chondroitin sulfate β-1,4-N-acetylgalactosaminyltransferase-1 (ChGn-1) polymorphism; association with progression of multiple sclerosis.2016

    • Author(s)
      Saigoh, K., Yoshimura, S., Izumikawa, T., Miyata, S., Tabara, Y., Matsushita, T., Miki, T., Miyamoto, K., Hirano, M., Kitagawa, H., Kita, J., and Kusunoki, S.
    • Journal Title

      Neurosci. Res.

      Volume: 印刷中 Pages: 55-59

    • DOI

      10.1016/j.neures.2016.01.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23110003, KAKENHI-PUBLICLY-26110721, KAKENHI-PROJECT-15H04845, KAKENHI-PROJECT-25293014, KAKENHI-PROJECT-16K09705, KAKENHI-PROJECT-16H05088
  • [Journal Article] A new mouse allele of glutamate receptor delta 2 with cerebellar atrophy and progressive ataxia2014

    • Author(s)
      Miyoshi, Y., Yoshioka, Y., Suzuki, K., Miyazaki, T., Koura, M., Saigoh, K., Kajimura, N., Monobe,Y., Kusunoki, S., Matsuda, J., Watanabe, M. and Hayakawa, N.
    • Journal Title

      PLoS ONE

      Volume: 9 (9) Issue: 9 Pages: 1-12

    • DOI

      10.1371/journal.pone.0107867

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-25293053, KAKENHI-PROJECT-26460250
  • [Journal Article] The significance of oxidized DJ-1 protein (oxDJ-1) as a biomarker for Parkinson’s disease.2014

    • Author(s)
      Ikuko Ogawa, Yoshiro Saito, Kazumasa Saigoh, Yoshie Hosoi, Yoshiyuki Mitsui, Noriko Noguchi, and Susumu Kusunoki
    • Journal Title

      Brain and Nerve

      Volume: 66 Pages: 471-477

    • NAID

      40020069623

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25670084
  • [Journal Article] Circadian expression and specific localization of a sialyltransferase gene in the suprachiasmatic nucleus.2013

    • Author(s)
      Hamada Y, Saigoh K, Masumoto KH, Nagano M, Kusunoki S, Shigeyoshi Y.
    • Journal Title

      Neurosci Lett.

      Volume: 22;535 Pages: 12-7

    • DOI

      10.1016/j.neulet.2012.12.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590232, KAKENHI-PROJECT-23590248, KAKENHI-PROJECT-23790277, KAKENHI-PROJECT-25860181
  • [Journal Article] Chondroitin beta-1, 4-N-acetylgalactosaminyltransferase-1 missense mutations are associated with neuropathies2011

    • Author(s)
      Saigoh K, et al
    • Journal Title

      Journal of Human Genetics

      Volume: 56(2) Pages: 143-146

    • NAID

      10030657886

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Journal Article] Chondroitin-1,4-N-acetylgalactosaminyltransferase -1 missense mutations are associated with neuropathies.2011

    • Author(s)
      Saigoh K, Izumikawa T, Koike T, Shimizu J, Kitagawa H, Kusunoki S.
    • Journal Title

      J Hum Genet.

      Volume: 56(2) Issue: 2 Pages: 143-6

    • DOI

      10.1038/jhg.2010.148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Journal Article] Chondroitin beta-1, 4-N-acetylgalactosaminyltransferase-1 missense mutations are associated with neuropathies.2010

    • Author(s)
      Saigoh K, et al.
    • Journal Title

      Journal of Human Genetics

    • NAID

      10030657886

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Presentation] パーキンソン病関連タンパク質DJ-1の新規修飾の同定2023

    • Author(s)
      松田康平1、三田雄一郎2、浦野泰臣1、西郷和真3、伊藤慎二4、斎藤芳郎5、野口範子
    • Organizer
      第76回日本酸化ストレス学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07547
  • [Presentation] Unknown modification of DJ-1 is increased in red blood cells from Unmedicated patients with Parkinson’s disease2022

    • Author(s)
      Matsuda K, Mita Y, Urano Y, Saigoh K, Ito S, Saito Y, Ogochi N
    • Organizer
      SfRBM(Society for Redox Biology and Medicine)29th Annual Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07547
  • [Presentation] Significant relationship of CTA/CTG repeat sizes with age at onset and phenotype in SCA82018

    • Author(s)
      Makoto Samukawa, Makito Hirano, Kazumasa Saigoh, Shigeru Kawai, Yukihiro Hamada, Daisuke Takahashi, Yusaku Nakamura, Susumu Kusunoki
    • Organizer
      American Neurological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] Analyses of non-coding repeat expansions in Japanese patients with amyotrophic lateral sclerosis reveals mutations in the ATXN8OS gene.2018

    • Author(s)
      Makito Hirano, Makoto Samukawa, Chiharu Isono, Kazumasa Saigoh,, Yusaku Nakamura, Susumu Kusunoki
    • Organizer
      American Neurological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] Mutations in the COQ2 gene in atypical phenotypes of neurodegenerative diseases and supplementation of coenzyme Q102017

    • Author(s)
      Makito Hirano, Yusaku Nakamura, Kazumasa Saigoh, Makoto Samukawa, Susumu Kusunoki
    • Organizer
      American Neurological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] Comparison of clinical features between a patient with intermediate CTA/CTG repeats and patients with 80 of longer CTA/CTG repeats in Spinocerebellar ataxia type 82017

    • Author(s)
      Makoto Samukawa, Makito Hirano, Kazumasa Saigoh, Susumu Kusunoki
    • Organizer
      American Neurological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] Genetic analyses and counselling of sporadic amyotrophic lateral sclerosis in Japan2016

    • Author(s)
      Makito Hirano, Yusaku Nakamura, Kazumasa Saigoh, Hikaru Sakamoto, Shuichi Ueno, Hidekazu Suzuki, Susumu Kusunoki
    • Organizer
      Annual Meeting of American Neurological Association
    • Place of Presentation
      ボルチモアマリオットホテル(米国ボルチモア)
    • Year and Date
      2016-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] Novel mutations and genetic counseling in sporadic amyotrophic lateral sclerosis2016

    • Author(s)
      Makito Hirano, Yusaku Nakamura, Kazumasa Saigoh, Hikaru Sakamoto, Shuichi Ueno, Hidekazu Suzuki, Susumu Kusunoki
    • Organizer
      日本神経学会総会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09705
  • [Presentation] 血中の酸化型DJ-1異常高値の臨床的意義2014

    • Author(s)
      西郷和真、斎藤芳郎、小川郁子、細井幸恵、三井良之、花田一志、上田昌美、石井一成、野口範子、楠進
    • Organizer
      第67回日本酸化ストレス学会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-04
    • Data Source
      KAKENHI-PROJECT-25670084
  • [Presentation] PDの診断マーカーである血中oxDJ-1の異常高値を示したDLBの4例2014

    • Author(s)
      西郷和真、斎藤芳郎、小川郁子、細井幸恵、三井良之、花田一志、上田昌美、石井一成、野口範子、楠進
    • Organizer
      第33回日本認知症学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-12-01
    • Data Source
      KAKENHI-PROJECT-25670084
  • [Presentation] Circadian Expression and Specific Localization of ST8 α-2,8-Sialyltransferase 6 mRNA in Mouse of Suprachiasmatic Nucleus2012

    • Author(s)
      saigoh k
    • Organizer
      NEUROSCIENCE 2012
    • Place of Presentation
      America New orleans
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Presentation] Circadian Expression and Specific Localization of ST8 α-2,8-Sialyltransferase 6 mRNA in Mouse of Suprachiasmatic Nucleus.2012

    • Author(s)
      Kazumasa Saigoh, Yoshiyuki Hamada, Susumu Kusunoki, Masumoto Kohei, Mamoru Nagano, Naoto Hayasaka, Yasufumi Shigeyoshi
    • Organizer
      Neuroscience 2012, SfN's 42nd annual meeting
    • Place of Presentation
      in New Orleans
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Presentation] コンドロイチン硫酸糖鎖合成酵素遺伝子の一塩基変異のみられたニューロパチーの検討(会議録)2011

    • Author(s)
      西郷和真(近畿大学医学部附属病院 神経内科), 泉川友美, 小池敏靖,清水 潤,北川 裕之, 楠 進
    • Organizer
      臨床神経学(0009-918X)51 巻12 号 Page1455
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Presentation] 運動ニューロン疾患と多巣性運動ニューロパチーとの抗糖脂質抗体における検討(会議録)2010

    • Author(s)
      西郷和真(近畿大学医学部神経内科), 桑原基, 塩山実章, 宮本勝一, 青松宏美,高田和男,三井良之,楠進
    • Organizer
      臨床神経学(0009-918X)50 巻12 号 Page1084
    • Data Source
      KAKENHI-PROJECT-22590232
  • [Presentation] 運動ニューロン疾患と多巣性運動ニューロバチーとの抗糖脂質抗体における検討2010

    • Author(s)
      西郷和真, 他
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590232
  • 1.  KUSUNOKI Susumu (90195438)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  HAYASAKA Naoto (80368290)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  HIRANO Makito (50347548)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 4.  MIYAMOTO Katsuichi (50388526)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Yoshiro Saito (70357060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  SHIGEYOSHI Yasufumi (20275192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  TSUBATA Takeshi (80197756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NOGUCHI Noriko (40198578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  徳田 功 (00261389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  吉岡 芳親 (00174897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  竹森 洋 (90273672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  篠田 晃 (40192108)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  桑原 基 (40460860)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  永井 義隆 (60335354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  山岸 裕子 (80826040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  三田 雄一郎 (70609122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  MIYATA Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  北川 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  鈴木 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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