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Seki Naohiko  関 直彦

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SEKI Naohiko  関 直彦

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Researcher Number 50345013
Other IDs
Affiliation (Current) 2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 千葉大学, 大学院医学研究院, 准教授
2011 – 2016: 千葉大学, 医学(系)研究科(研究院), 准教授
2013: 千葉大学, 大学院医学研究院, 准教授
2007 – 2012: Chiba University, Graduate School, Dept Genome Sci, Assoc Prof
2010: 千葉大学, 機能ゲノム学, 准教授 … More
2006: Chiba University, School of Medicine, Associate Professor, 医学部, 助教授
2005 – 2006: 千葉大学, 大学院医学研究院, 助教授
2005: 千葉大学, 大学院・医学部研究院, 助教授
2002 – 2005: Chiba University, Graduate School of Medicine, Associate Professor, 大学院・医学研究院, 助教授 Less
Review Section/Research Field
Principal Investigator
Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Thoracic surgery
Except Principal Investigator
Urology / Otorhinolaryngology / Basic Section 53030:Respiratory medicine-related / Basic Section 55020:Digestive surgery-related / Thoracic surgery / Basic Section 55010:General surgery and pediatric surgery-related / Respiratory organ internal medicine … More / Surgical dentistry / Basic Section 56050:Otorhinolaryngology-related / Basic Section 56030:Urology-related / Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Radiation science / Applied health science / Digestive surgery / Orthopaedic surgery / Tumor diagnostics Less
Keywords
Principal Investigator
マイクロRNA / 機能性RNA / 頭頸部扁平上皮癌 / 癌抑制遺伝子 / 治療抵抗性 / スーパーエンハンサー / 口腔扁平上皮癌細胞 / 頭頸部扁平上皮癌細胞 / 癌抑制型マイクロRNA / 頭頸部癌 … More / 発現プロファイル / 転写調節領域 / 薬剤耐性 / H3K27ac / シスプラチン / ATAC-sequence / プロファイル / TCGA / miR-30e-5p / 癌遺伝子 / マイクロRNA発現プロファイル / miR-99a-3p / miR-99a-5p / 受容体 / シグナル伝達 / MET / c-MET / EGFR / 癌促進型マイクロRNA / インテグリン / Lung cancer / Immunotherapy / Chromosome / Gene / Microarray / 肺癌 / 免疫療法 / 染色体 / 遺伝子 / マイクロアレイ / 扁平上皮癌 / ゲノム / 転移 / 分子ネットワーク / 下咽頭癌 / 頭頚部扁平上皮癌 / 機能性核酸 / 癌 … More
Except Principal Investigator
マイクロRNA / microRNA / マイクロアレイ / 治療抵抗性 / 肺癌 / 癌抑制遺伝子 / 頭頸部扁平上皮癌 / マイクロRNA / 前立腺癌 / 膀胱癌 / スーパーエンハンサー / エクソソーム / 機能性RNA / 口腔癌 / ゲノム / オルガノイド / シスプラチン / stathmin / maspin / cDNA microarray / 予後 / 腎細胞癌 / 去勢抵抗性 / 扁平上皮癌 / 発現プロファイル / がん抑制遺伝子 / 癌 / 口腔扁平上皮癌 / 抗癌剤耐性 / 転写因子 / 転写調節領域 / miR-99a-3p / 小細胞肺癌 / 癌遺伝子 / 転移 / 去勢抵抗性前立腺癌 / ナノミセル / 頭頸部癌 / 浸潤 / 遺伝子解析 / NBI / 尿路上皮癌 / cDNA / 遺伝子発現プロファイリング / DNAチップ / ATAC sequence / miR-99a-5p / トリプルネガティブ乳癌 / 乳癌 / 分子細胞呼吸器学 / 肺扁平上皮癌 / 3D培養 / 核酸 / 薬剤耐性 / 腎癌 / 細胞外マトリックス / PET / 抗がん剤 / siRNA / MMP-1 / SNP / p14ARF / p16INK4a / CKS1 / SKP2 / 放射線感受性 / VEGF / COPD / peptide mass fingerprinting / MS / MALDI-TOF / 2D-DIGE / Prognosis / Microarray / Lung cancer / salivary gland tumor / microarray analysis / oral cancer / 唾液腺癌 / マイクロアレイ解析 / cDNAマイクロアレイ / TNF-alpha / knock-out mouse / periostin / fracture repair / bone formation / mouse / gene expression / microarray / 腺癌 / oral squamous cell carcinoma / DNA microarray / 化学療法 / 分子標的薬 / セツキシマブ / 癌抑制型マイクロRNA / 転移抑制 / 癌抑制 / がん / 遺伝子 / 下咽頭癌 / 蛍光電子内視鏡 / 腫瘍マーカー / 外科 / 喫煙 / ATAC-sequenc / 口腔扁平上皮癌細胞 / ノンコーディングRNA / 人工合成環状RNA / non coding RNA / 環状RNA / 消化器癌治療耐性因子 / ATAC-seq / クロマチン変化 / マスター分子 / 膵癌 / 養子免疫療法 / ネオアンチゲン / 脳転移 / HER2陽性 / 癌関連線維芽細胞 / 細胞外小胞 / シークエンス / シークセンス / 血清 / 免疫沈降法 / H3K27ac / ATAC-sequence / 頭頸部扁平上皮癌細胞 / ATACシークエンス / miRNA / 消化器癌 / micro RNA / 分化転換 / 消化器固形癌 / 頭頚部扁平上皮癌 / miR-199 / マクロRNA / がん遺伝子 / 機能性RNAネットワーク / 食道扁平上皮癌 / 大腸癌 / プロファイル / FAM64A / miR-204-5p / AP1S3 / GINS1 / miR-101-5p / トリプルネガティブ / 間質性肺炎合併肺癌 / 間質性肺炎 / 間質性合併肺癌 / CRISPR-Cas9 / ドラッグリポジショニング / MCMファミリー / 治療標的分子 / パッセンジャー鎖 / 3D培養 / Notch / 癌幹細胞 / heterogeneity / 肺線維症 / 特発性肺線維症 / 網羅的解析 / ネットワーク / 次世代シークエンサー / CRPC / ホルモン感受性 / 次世代シーケンサー / DONSON / 核酸医薬 / シグナル伝達 / 治療標的型マイクロRNA / miRNA-223 / miRNA-199 / スニチニブ耐性 / microRNA / 泌尿器癌 / 低酸素 / MET / bronchial dysplasia / high resolution bronchovideoscopy / AFI / 気管支dysplasia / 高解像度気管支ビデオスコープ / Cell cycle / Multi-modality therapy / Radiotherapy / Gene expression / Cisplatin / 放射線 / 細胞周期 / マルチモダリティー治療 / 放射線治療 / 遺伝子発現 / tailor-made treatment / テーラーメイド治療 / Genetherapy / Radiation sensitivity / 遺伝子治療 / joint space width / home-base exercise / knee osteoarethritis / 自然経過 / 有効性 / 運動療法 / 間接裂隙 / ホームエクササイズ / 変形性膝関節症 / DNA methylation / prognosis / invasiveness / Bladder cancer / 再発 / クラスター解析 / DNAマイクロアレイ / DNAメチル化 / 浸潤性 / gene expression profile / radiosensitivity / human squamous cell carcinoma / 遺伝子発現解析 / 消化器扁平上皮癌 / Mouse / Bone Marrow / Endothelial Progenitor Cells / Smoking / Emphysema / マウス / 骨髄 / 肺気腫 / 血管内皮前駆細胞 / profiling of protein expression / petide mass fingerprinting / _2D-DIGE / タンパク発現プロファイリング / タンパク発現プロファイリ / adenoid cystic carcinoma / 唾液腺腫瘍 / 線様嚢胞癌 / 腺様嚢胞癌 / cDNA MICROARRAY / LAMP AMPLIFICATION / SENTINEL LYMPH NODE / MICROMETASTASIS / GASTRIC CANCER / 微小転移診断 / LAMP法遺伝子増幅 / センチネルリンパ節生検 / 微小転移 / 胃癌 / pleomorphic adenoma / squamous cell carcinoma / 遺伝子クローニング / 庸平上皮癌 / 遺伝子機能評価 / 仮骨 / RT-PCR / Northern blotting / in situ hybridization / periostin(ペリオスチン) / 骨折治癒 / risk for malignant grade / risk for micrometastasis / risk for carcinogenesis / diagnosis / 悪性度評価法 / 悪牲度評価 / 悪性度評価 / drug resistance / chemotherapy / 薬剤感受性 / 分子ネットワーク / EGFR / 上皮成長因子受容体 / 治療効果予測因子 / ゲノムシークエンス / microRNA / CDK6 / miR-504 / 膀胱がん / アジュバンド療法 / 先進医療 / アジュバント療法 / 細胞障害性T細胞 / 悪性黒色腫 / 癌免疫療法 / NKT細胞 / 上顎癌 / HDAC1 / miR-874 / 上顎洞癌 / 発癌 / 増殖 / 標的遺伝子 / 細胞増殖 / PC3 / 標的遺伝子解析 / アポトーシス / ニューロテンシン / 神経ペプチド / 蛍光電子視鏡 / 気管支異形成 / 超拡大内視鏡 / 診断マーカー / FSCN1 / -マイクロアレイ / 呼吸器外科学 / 唾液腺 / 飲酒 / 発癌予防法 / 発癌抵抗性 Less
  • Research Projects

    (80 results)
  • Research Products

    (247 results)
  • Co-Researchers

    (115 People)
  •  合成致死性に基づいたKRAS変異陽性肺癌におけるソトラシブ併用新規治療法の開発

    • Principal Investigator
      萩原 陽子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  肺癌細胞が血液脳関門を破錠し、脳転移を可能にする機能性RNAネットワークの解明

    • Principal Investigator
      末次 隆行
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  オープンクロマチン領域を指標とした小細胞肺癌薬物耐性に関する分子機構の解明

    • Principal Investigator
      眞田 宏樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  HER2陽性乳癌細胞が脳転移を可能にする際に関与する機能性RNA分子の解明

    • Principal Investigator
      満枝 怜子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
  •  Future Prospects for Novel Colorectal Cancer Immunotherapy Focusing on Exosome-Derived MicroRNAs

    • Principal Investigator
      和田 真澄
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  膵癌治療抵抗性への挑戦:機能性RNAの「時間的」階層性によるマスター分子の探求

    • Principal Investigator
      伊地知 徹也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  クロマチン変化の時間軸に着目した消化器癌治療耐性因子の解明

    • Principal Investigator
      喜多 芳昭
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  機能性RNA時間的階層性に基づく腎癌細胞の薬剤耐性獲得に関わるマスター分子の探索

    • Principal Investigator
      加藤 繭子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  機能性RNA分子・時間的階層性の理解に基づく、頭頸部癌・薬剤耐性獲得機構の解明Principal Investigator

    • Principal Investigator
      関 直彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  転写調節領域を指標にした抗癌剤耐性獲得に関わる機能性RNAの探索

    • Principal Investigator
      峯村 周
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      National Defense Medical College
  •  治療抵抗性獲得に関与する小細胞肺癌機能性RNA分子アトラスの構築

    • Principal Investigator
      水野 圭子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  トリプルネガティブ乳癌・転写調節領域解析に基づく抗癌剤耐性機構の解明

    • Principal Investigator
      戸田 洋子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
      Fujita Health University
  •  頭頸部扁平上皮癌・スーパーエンハンサー解析に基づく抗癌剤耐性機構の解明

    • Principal Investigator
      吉川 直子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  細胞外小胞を介した口腔扁平上皮癌細胞の悪性化能獲得機構の解明

    • Principal Investigator
      木下 崇
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Elucidation of the mechanism of inhibition of cancer progression and development of new drugs by artificial synthetic cyclic RNAs

    • Principal Investigator
      笠松 厚志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  Basic research for trans-differentiation using 3D culture in gastro-intentional cancer

    • Principal Investigator
      Kita Yoshiaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Identification of super-enhancer and master genes involved in treatment resistance of urothelial cancer

    • Principal Investigator
      KATO MAYUKO
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  The study of transcriptional regulation of functional RNAs involved in drug resistance in head and neck cancerPrincipal Investigator

    • Principal Investigator
      関 直彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  Exploration Study of Molecular Pathways and Novel Therapies in Lung Squamous Cell Carcinoma Initiated by MicroRNAs

    • Principal Investigator
      Uchida Akifumi
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  Devising drug repositioning based on functional RNA integration analysis of small cell lung cancer.

    • Principal Investigator
      Mizuno Keiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  Exploration of molecular pathways for lung cancer with interstitial pneumonia and development of new treatments based on understanding of functional RNA integration

    • Principal Investigator
      Sanada Hiroki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kagoshima University
  •  Elucidation of therapeutic target molecular pathway by understanding tripli negative breast cancer and functional RNA integration

    • Principal Investigator
      Toda Hiroko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Fujita Health University
      Kagoshima University
  •  Diagnostic and identification of therapeutic target molecules based on functional RNA network search in colorectal cancer.

    • Principal Investigator
      吉満 工平
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
  •  Elucidation of molecular pathogenesis of esophageal squamous cell carcinoma based on comprehensive functional RNA analysis

    • Principal Investigator
      Wada Masumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kagoshima University
  •  Drug repositioning strategy of head and neck squamous cell carcinoma after treatment failure based on microRNA analysis

    • Principal Investigator
      Kikkawa Naoko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  食道扁平上皮癌オルガノイド・マイクロRNA解析による治療抵抗性分子経路の解明

    • Principal Investigator
      下之薗 将貴
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  The basic research about cancer heterogeneity using 3D and co-culture for precision medicine

    • Principal Investigator
      KITA YOSHIAKI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Molecular signature of head and neck squamous cell carcinoma after treatment failure based on functional RNA analysisPrincipal Investigator

    • Principal Investigator
      SEKI NAOHIKO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  浸潤性膀胱癌・オルガノイド培養系を用いた機能性RNA解析と術前化学療法の最適化

    • Principal Investigator
      菅原 翔
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  Development of innovative therapy for treatment-resistant small cell lung cancer based on functional RNA network analysis

    • Principal Investigator
      KUMAMOTO TOMOHIRO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kagoshima University
  •  Elucidate the functional RNA network in castration-resistant prostate cancer and therapeutic approach

    • Principal Investigator
      Kojima Satoko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Teikyo University
  •  Identification of drug-resistance related RNA networks in head and neck squamous cell carcinoma cells

    • Principal Investigator
      HANAZAWA TOYOYUKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Elucidation of the microRNA-mediated RNA networks in castration resistant prostate cancer and development of innovative treatments

    • Principal Investigator
      Ichikawa Tomohiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Chiba University
  •  Exploring molecular network of functional nucleic acid and developing therapeutic innovations in drug-resistant renal cell carcinoma

    • Principal Investigator
      NAKAGAWA Masayuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Development of the innovative treatment based on the search of microRNA blocking growth signals in urothelial carcinoma

    • Principal Investigator
      YOSHINO Hirofumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Identification of activated molecular pathways involved in treatment-resistant head and neck squamous cell carcinoma

    • Principal Investigator
      KIKKAWA NAOKO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Development of nuclear acid medicine by using tumor suppressive microRNA conjugated with high molecular nano-micelle

    • Principal Investigator
      TATARANO Shuichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Investigation of the common RNA networks in lung cancer and idiopathic pulmonary fibrosis for the new strategy of the diseases.

    • Principal Investigator
      MATAKI Hiroko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kagoshima University
  •  Elucidation of extracellular matrix molecular pathway regulated by metastasis-suppressing microRNAs in prostate cancer.

    • Principal Investigator
      KATO MAYUKO
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Chiba University
  •  Elucidation of the extracellular matrix signal mechanism controled by tumor suppressor microRNAs in head and neck cancer

    • Principal Investigator
      Ichiro Fukumoto
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Southen Tohoku Research Institute for Neuroscience
      Chiba University
  •  Development of novel therapeutic strategies in head and neck squamous cell carcinoma based on microRNA-mediated cancer pathwaysPrincipal Investigator

    • Principal Investigator
      SEKI NAOHIKO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Development of novel nucleic acid treatment through nano-micelles delivering tumor suppressive microRNA in bladder cancer

    • Principal Investigator
      ENOKIDA Hideki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Study for elucidating tumor suppressive microRNA that has anti proliferation and prevent metastasis by using metastasis model mouse in bladder cancer

    • Principal Investigator
      ITESAKO Toshihiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Analysis of functional RNA networks and investigation of their target genes in castration-resistant prostate cancer (CRPC).

    • Principal Investigator
      Kojima Satoko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Teikyo University
  •  Investigation into the predictor of cetuximab effect based on microRNA in head and neck squamous cell carcinoma

    • Principal Investigator
      Hanazawa Toyoyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Investigation of hypoxia resistance in renal cell carcinoma based on functional RNA network analyses

    • Principal Investigator
      Chiyomaru Takeshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Clarification of microRNA functional networks and development of novel tools for diagnosis and treatment of castration-resistant prostate cancer

    • Principal Investigator
      Ichikawa Tomohiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Chiba University
  •  Development of novel tumor markers for renal cell carcinoma by evaluating small nuclear acid in blood

    • Principal Investigator
      tatarano shuichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kagoshima University
  •  Order made therapy for bladder cancer by investigating functional RNAs associated molecular networks

    • Principal Investigator
      Nakagawa Masayuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Development of new therapeutic strategies of hypopharyngeal cancer based on the RNA network analysis

    • Principal Investigator
      KIKKAWA Naoko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Development of adjuvant therapy for head and neck cancer by activation of NKT cells via nasal mucosa

    • Principal Investigator
      Okamoto Yoshitaka
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Identification of tumor-suppressive microRNAs regulating metastatic pathways in HNSCCPrincipal Investigator

    • Principal Investigator
      SEKI Naohiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Analysis of gene regulation networks controlled by microRNA in castration resistant prostate cancer

    • Principal Investigator
      KOJIMA Satoko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Teikyo University
  •  Identification of tumor suppressive nucleic acid medicine in maxillary sinus squamous cell carcionma

    • Principal Investigator
      HANAZAWA Toyoyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Anti-proliferative miRNA expression in squamous cell carcinoma of the lung: Pursue for the common therapeutic targets of the tobacco-related cancer

    • Principal Investigator
      MORIYA Yasumitsu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
      Chiba University
  •  Identification of differentially expressed microRNAs in head and neck squamous cell carcinoma based on microRNA expression signaturePrincipal Investigator

    • Principal Investigator
      SEKI Naohiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Analysis of function and the target genes of micro-RNAs in prostate cancer

    • Principal Investigator
      KOJIMA Satoko
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Teikyo University
  •  Developing new treatment modalities of urothelial carcinoma through regulating microRNA expression

    • Principal Investigator
      NAKAGAWA Masayuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  新しい超拡大内視鏡システムとマイクロアレイによる気管支異形成遺伝子発現の解析

    • Principal Investigator
      渋谷 潔
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Role of Neuropeptide Signals Induced Metastasis of Hypopharyngeal Cancer

    • Principal Investigator
      HANAZAWA Toyoyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer

    • Principal Investigator
      IYODA Akira
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kitasato University
      Chiba University
  •  Screening and validation of target molecules involved in mechanism of multi-modality therapy

    • Principal Investigator
      TAKIGUCHI Yuichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Chiba University
  •  The treatment strategy of bronchial dysplasia using a novel autofluorescence imaging bronchovideoscope system and microarray

    • Principal Investigator
      SHIBUYA Kiyoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Efficacy and natural course of therapeutic exercise for patients with knee osteoarthritis : Analysis by SNP

    • Principal Investigator
      KUROSAWA Hisashi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Juntendo University
  •  The development of the novel genetherapy to enhance the radiation sensitivity.

    • Principal Investigator
      NIMURA Yoshinori
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  The strategy based on gene expression profiling using microarray for tailor-made treatment in patients with lung cancer

    • Principal Investigator
      IYODA Akira
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Development of cancer immunotherapy using cancer-specific peptide based on genome analysisPrincipal Investigator

    • Principal Investigator
      SEKI Naohiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Identification of proteins associated with oral cancer by global proteomic approach.

    • Principal Investigator
      TANZAWA Hideki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Role of Endothelial progenitor Cell in the pathogenesis of COPD

    • Principal Investigator
      KASAHARA Yasunori
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Chiba University
  •  Construction of in-house cDNA microarrays for identifying radiotherapeutic molecular markers in human aquamous cell carcinoma

    • Principal Investigator
      UZAWA Katsuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Establishment of prediction system for the prognosis of patients with bladder cancer

    • Principal Investigator
      NAKAGAWA Masayuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  唾液腺組織のcDNAライブラリー作成と唾液腺疾患用DNAチップの開発作製

    • Principal Investigator
      丹沢 秀樹
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Search for oral cancer specific genes and molecular cloning using in-house cDNA microaray

    • Principal Investigator
      SHIBA Masashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  ESTABLISHMENT OF AN INTRA-OPERATIVE TECHNIQUE FOE DETECTION OF MICROMETASTASES IN GASTRIC CANCER SURGERY USING LAMP GENE AMPLIFICATION.

    • Principal Investigator
      HAYASHI Hedeki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  Gene expression profiling in primary lung cancer with oligonucleotide microarray.

    • Principal Investigator
      IYODA Akira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Gene profiling in adenoid cystic carcinoma cells using in-house cDNA microaray

    • Principal Investigator
      YOKOE Hidetaka
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  独自に開発したDNAチップを用いた発癌因子抵抗性評価および発癌予防法の開発

    • Principal Investigator
      宮川 昌久
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Development of the method to select the most effective anti-cancer chemotherapy using in-house cDNA microarray

    • Principal Investigator
      UZAWA Katsuhiro, 宮川 昌久
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Development of the diagnostic method to evaluate the risks for carcinogenesis, micro-metastasis, and malignant grade of oral cancer using in-house cDNA microarray

    • Principal Investigator
      TANZAWA Hideki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Identification of novel genes regulating fracture healing and their functional analyzes

    • Principal Investigator
      YAMAZAKI Masashi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation Patent Other

  • [Journal Article] Coronin 1C, Regulated by Multiple microRNAs, Facilitates Cancer Cell Aggressiveness in Pancreatic Ductal Adenocarcinoma2023

    • Author(s)
      Fukuda Kosuke、Seki Naohiko、Yasudome Ryutaro、Mitsueda Reiko、Asai Shunichi、Kato Mayuko、Idichi Tetsuya、Kurahara Hiroshi、Ohtsuka Takao
    • Journal Title

      Genes

      Volume: 14 Issue: 5 Pages: 995-995

    • DOI

      10.3390/genes14050995

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16426, KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-21K08783, KAKENHI-PROJECT-21K09367
  • [Journal Article] MiR-15b-5p inhibits castration-resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM32023

    • Author(s)
      Shunichi Asai, Yusuke Goto, Kengo Tanigawa, Yuya Tomioka, Mayuko Kato, Keiko Mizuno, Shinichi Sakamoto, Naohiko Seki
    • Journal Title

      FEBS Letter

      Volume: - Issue: 8 Pages: 1164-1175

    • DOI

      10.1002/1873-3468.14598

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09367, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-21K16753
  • [Journal Article] Identification of MicroRNAs Associated with Histological Grade in Early-Stage Invasive Breast Cancer2023

    • Author(s)
      Kurozumi Sasagu、Seki Naohiko、Narusawa Eriko、Honda Chikako、Tokuda Shoko、Nakazawa Yuko、Yokobori Takehiko、Katayama Ayaka、Mongan Nigel P.、Rakha Emad A.、Oyama Tetsunari、Fujii Takaaki、Shirabe Ken、Horiguchi Jun
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 1 Pages: 35-35

    • DOI

      10.3390/ijms25010035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09577
  • [Journal Article] Oncogenic Targets Regulated by Tumor-Suppressive miR-30c-1-3p and miR-30c-2-3p: TRIP13 Facilitates Cancer Cell Aggressiveness in Breast Cancer2023

    • Author(s)
      Mitsueda Reiko、Toda Hiroko、Shinden Yoshiaki、Fukuda Kosuke、Yasudome Ryutaro、Kato Mayuko、Kikkawa Naoko、Ohtsuka Takao、Nakajo Akihiro、Seki Naohiko
    • Journal Title

      Cancers

      Volume: 15 Issue: 16 Pages: 4189-4189

    • DOI

      10.3390/cancers15164189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K08705, KAKENHI-PROJECT-22K09679, KAKENHI-PROJECT-21K08783, KAKENHI-PROJECT-21K09367
  • [Journal Article] The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma2023

    • Author(s)
      Tomioka Yuya、Suetsugu Takayuki、Seki Naohiko、Tanigawa Kengo、Hagihara Yoko、Shinmura Masahiro、Asai Shunichi、Kikkawa Naoko、Inoue Hiromasa、Mizuno Keiko
    • Journal Title

      Cells

      Volume: 12 Issue: 14 Pages: 1885-1885

    • DOI

      10.3390/cells12141885

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679
  • [Journal Article] Minichromosome maintenance proteins in lung adenocarcinoma: Clinical significance and therapeutic targets2023

    • Author(s)
      Tanigawa Kengo、Tomioka Yuya、Misono Shunsuke、Asai Shunichi、Kikkawa Naoko、Hagihara Yoko、Suetsugu Takayuki、Inoue Hiromasa、Mizuno Keiko、Seki Naohiko
    • Journal Title

      FEBS Open Bio

      Volume: 13 Issue: 9 Pages: 1737-1755

    • DOI

      10.1002/2211-5463.13681

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16196, KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679
  • [Journal Article] Molecular Pathogenesis of Colorectal Cancer: Impact of Oncogenic Targets Regulated by Tumor Suppressive miR-139-3p.2022

    • Author(s)
      Yasudome R, Seki N, Asai S, Goto Y, Kita Y, Hozaka Y, Wada M, Tanabe K, Idichi T, Mori S, Ohtsuka T.
    • Journal Title

      Int J Mol Sci.

      Volume: 23 Issue: 19 Pages: 11616-11616

    • DOI

      10.3390/ijms231911616

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08783, KAKENHI-PROJECT-21K16426, KAKENHI-PROJECT-22K16514
  • [Journal Article] Identification of Antitumor miR-30e-5p Controlled Genes; Diagnostic and Prognostic Biomarkers for Head and Neck Squamous Cell Carcinoma2022

    • Author(s)
      Chikashi Minemura, Shunichi Asai, Ayaka Koma, Naoko Kikkawa, Mayuko Kato, Atsushi Kasamatsu, Katsuhiro Uzawa, Toyoyuki Hanazawa, Naohiko Seki
    • Journal Title

      Genes(Basel)

      Volume: 13 Issue: 7 Pages: 1-21

    • DOI

      10.3390/genes13071225

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09367, KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679
  • [Journal Article] Impact of miR-1/miR-133 Clustered miRNAs: PFN2 Facilitates Malignant Phenotypes in Head and Neck Squamous Cell Carcinoma2022

    • Author(s)
      Asai Shunichi、Koma Ayaka、Nohata Nijiro、Kinoshita Takashi、Kikkawa Naoko、Kato Mayuko、Minemura Chikashi、Uzawa Katsuhiro、Hanazawa Toyoyuki、Seki Naohiko
    • Journal Title

      Biomedicines

      Volume: 10 Issue: 3 Pages: 663-663

    • DOI

      10.3390/biomedicines10030663

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
  • [Journal Article] Genome-Wide Super-Enhancer-Based Analysis: Identification of Prognostic Genes in Oral Squamous Cell Carcinoma2022

    • Author(s)
      Saito Tomoaki、Asai Shunichi、Tanaka Nozomi、Nohata Nijiro、Minemura Chikashi、Koma Ayaka、Kikkawa Naoko、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 16 Pages: 9154-9154

    • DOI

      10.3390/ijms23169154

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679, KAKENHI-PROJECT-20H03883
  • [Journal Article] MicroRNA signature of small‐cell lung cancer after treatment failure: impact on oncogenic targets by miR‐30a‐3p control2022

    • Author(s)
      Tanigawa Kengo、Misono Shunsuke、Mizuno Keiko、Asai Shunichi、Suetsugu Takayuki、Uchida Akifumi、Kawano Minami、Inoue Hiromasa、Seki Naohiko
    • Journal Title

      Molecular Oncology

      Volume: 17 Issue: 2 Pages: 328-343

    • DOI

      10.1002/1878-0261.13339

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16196, KAKENHI-PROJECT-21K09577
  • [Journal Article] Impact of miR-1/miR-133 clustered miRNAs: PFN2 facilitates malignant phenotypes in head and neck squamous cell carcinoma2022

    • Author(s)
      Shunichi Asai, Ayaka Koma, Nijiro Nohata, Takashi Kinoshita, Naoko Kikkawa, Mayuko Kato, Chikashi Minemura, Katsuhiro Uzawa, Toyoyuki Hanazawa, Naohiko Seki
    • Journal Title

      Biomedicines

      Volume: 10 Pages: 1-19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09367
  • [Journal Article] Molecular Pathogenesis and Regulation of the miR-29-3p-Family: Involvement of ITGA6 and ITGB1 in Intra-Hepatic Cholangiocarcinoma2021

    • Author(s)
      Hozaka Yuto、Seki Naohiko、Tanaka Takako、Asai Shunichi、Moriya Shogo、Idichi Tetsuya、Wada Masumi、Tanoue Kiyonori、Kawasaki Yota、Mataki Yuko、Kurahara Hiroshi、Ohtsuka Takao
    • Journal Title

      Cancers

      Volume: 13 Issue: 11 Pages: 2804-2804

    • DOI

      10.3390/cancers13112804

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09077, KAKENHI-PROJECT-21K16453
  • [Journal Article] Impact of Oncogenic Targets Controlled by Tumor-Suppressive <i>miR-30a-5p</i> in Pancreatic Ductal Adenocarcinoma2021

    • Author(s)
      NEPAL PRAMOD、HOZAKA YUTO、TANAKA TAKAKO、WADA MASUMI、ASAI SHUNICHI、MINEMURA CHIKASHI、IDICHI TETSUYA、ARIGAMI TAKAAKI、KURAHARA HIROSHI、SEKI NAOHIKO、OHTSUKA TAKAO
    • Journal Title

      Anticancer Research

      Volume: 41 Issue: 10 Pages: 4821-4836

    • DOI

      10.21873/anticanres.15297

    • Data Source
      KAKENHI-PROJECT-19K09077, KAKENHI-PROJECT-21K16426
  • [Journal Article] Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma2021

    • Author(s)
      Koma Ayaka、Asai Shunichi、Minemura Chikashi、Oshima Sachi、Kinoshita Takashi、Kikkawa Naoko、Koshizuka Keiichi、Moriya Shogo、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 18 Pages: 9947-9947

    • DOI

      10.3390/ijms22189947

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
  • [Journal Article] Identification of miR-199-5p and miR-199-3p Target Genes: Paxillin Facilities Cancer Cell Aggressiveness in Head and Neck Squamous Cell Carcinoma2021

    • Author(s)
      Tanaka Nozomi、Minemura Chikashi、Asai Shunichi、Kikkawa Naoko、Kinoshita Takashi、Oshima Sachi、Koma Ayaka、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
    • Journal Title

      Genes

      Volume: 12 Issue: 12 Pages: 1910-1910

    • DOI

      10.3390/genes12121910

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
  • [Journal Article] RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by miR-490-3p2021

    • Author(s)
      Hozaka Yuto、Kita Yoshiaki、Yasudome Ryutaro、Tanaka Takako、Wada Masumi、Idichi Tetsuya、Tanabe Kan、Asai Shunichi、Moriya Shogo、Toda Hiroko、Mori Shinichiro、Kurahara Hiroshi、Ohtsuka Takao、Seki Naohiko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 18 Pages: 9876-9876

    • DOI

      10.3390/ijms22189876

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09049, KAKENHI-PROJECT-19K09077, KAKENHI-PROJECT-21K08783
  • [Journal Article] Molecular Signature of Small Cell Lung Cancer after Treatment Failure: The MCM Complex as Therapeutic Target2021

    • Author(s)
      Misono Shunsuke、Mizuno Keiko、Suetsugu Takayuki、Tanigawa Kengo、Nohata Nijiro、Uchida Akifumi、Sanada Hiroki、Okada Reona、Moriya Shogo、Inoue Hiromasa、Seki Naohiko
    • Journal Title

      Cancers

      Volume: 13 Issue: 6 Pages: 1187-1187

    • DOI

      10.3390/cancers13061187

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08627, KAKENHI-PROJECT-19K08656, KAKENHI-PROJECT-19K17640
  • [Journal Article] Molecular Pathogenesis of the Coronin Family: CORO2A Facilitates Migration and Invasion Abilities in Oral Squamous Cell Carcinoma2021

    • Author(s)
      Kase-Kato Ikuko、Asai Shunichi、Minemura Chikashi、Tsuneizumi Kenta、Oshima Sachi、Koma Ayaka、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 23 Pages: 12684-12684

    • DOI

      10.3390/ijms222312684

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09577
  • [Journal Article] Regulation of Oncogenic Targets by Tumor-Suppressive miR-150-3p in Lung Squamous Cell Carcinoma2021

    • Author(s)
      Mizuno Keiko、Tanigawa Kengo、Misono Shunsuke、Suetsugu Takayuki、Sanada Hiroki、Uchida Akifumi、Kawano Minami、Machida Kentaro、Asai Shunichi、Moriya Shogo、Inoue Hiromasa、Seki Naohiko
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 12 Pages: 1883-1883

    • DOI

      10.3390/biomedicines9121883

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08627, KAKENHI-PROJECT-19K08656, KAKENHI-PROJECT-21K09577
  • [Journal Article] Molecular pathogenesis of breast cancer: impact of miR-99a-5p and miR-99a-3p regulation on oncogenic genes2020

    • Author(s)
      Shinden Yoshiaki、Hirashima Tadahiro、Nohata Nijiro、Toda Hiroko、Okada Reona、Asai Shunichi、Tanaka Takako、Hozaka Yuto、Ohtsuka Takao、Kijima Yuko、Seki Naohiko
    • Journal Title

      Journal of Human Genetics

      Volume: 66 Issue: 5 Pages: 519-534

    • DOI

      10.1038/s10038-020-00865-y

    • Data Source
      KAKENHI-PROJECT-19K09049
  • [Journal Article] Regulation of aberrantly expressed SERPINH1 by antitumor miR-148a-5p inhibits cancer cell aggressiveness in gastric cancer.2020

    • Author(s)
      Kawagoe K, Wada M, Idichi T, Okada R, Yamada Y, Moriya S, Okubo K, Matsushita D, Arigami T, Kurahara H, Maemura K, Natsugoe S, Seki N.
    • Journal Title

      J Hum Genet

      Volume: - Issue: 8 Pages: 647-656

    • DOI

      10.1038/s10038-020-0746-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08687
  • [Journal Article] Molecular Pathogenesis of Pancreatic Ductal Adenocarcinoma: Impact of miR-30c-5p and miR-30c-2-3p Regulation on Oncogenic Genes.2020

    • Author(s)
      Tanaka T, Okada R, Hozaka Y, Wada M, Moriya S, Satake S, Idichi T, Kurahara H, Ohtsuka T, Seki N.
    • Journal Title

      Cancers

      Volume: 12 Issue: 10 Pages: 2731-2731

    • DOI

      10.3390/cancers12102731

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08626, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-18K16322
  • [Journal Article] FAM64A: A Novel Oncogenic Target of Lung Adenocarcinoma Regulated by Both Strands of miR-99a (miR-99a-5p and miR-99a-3p)2020

    • Author(s)
      Mizuno Keiko、Tanigawa Kengo、Nohata Nijiro、Misono Shunsuke、Okada Reona、Asai Shunichi、Moriya Shogo、Suetsugu Takayuki、Inoue Hiromasa、Seki Naohiko
    • Journal Title

      Cells

      Volume: 9 Issue: 9 Pages: 2083-2083

    • DOI

      10.3390/cells9092083

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09338
  • [Journal Article] Regulation of Oncogenic Targets by miR-99a-3p (Passenger Strand of miR-99a-Duplex) in Head and Neck Squamous Cell Carcinoma2019

    • Author(s)
      Okada Reona、Koshizuka Keiichi、Yamada Yasutaka、Moriya Shogo、Kikkawa Naoko、Kinoshita Takashi、Hanazawa Toyoyuki、Seki Naohiko
    • Journal Title

      Cells

      Volume: 8 Issue: 12 Pages: 1535-1535

    • DOI

      10.3390/cells8121535

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-19K18795, KAKENHI-PROJECT-17K11375
  • [Journal Article] Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma.2019

    • Author(s)
      Yamada Y, Arai T, Kato M, Kojima S, Sakamoto S, Komiya A, Naya Y, Ichikawa T, Seki N.
    • Journal Title

      American Journal of Clinical and Experimental Urology

      Volume: 7 Pages: 11-30

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05462
  • [Journal Article] Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 Regulation.2019

    • Author(s)
      Khalid M, Idichi T, Seki N, Wada M, Yamada Y, Fukuhisa H, Toda H, Kita Y, Kawasaki Y, Tanoue K, Kurahara H, Mataki Y, Maemura K, Natsugoe S.
    • Journal Title

      Cancers (Basel)

      Volume: 11 Issue: 3 Pages: 327-327

    • DOI

      10.3390/cancers11030327

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K19945, KAKENHI-PROJECT-18K08626, KAKENHI-PROJECT-18K15219
  • [Journal Article] Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS8.2019

    • Author(s)
      Fukuhisa H, Seki N, Idichi T, Kurahara H, Yamada Y, Toda H, Kita Y, Kawasaki Y, Tanoue K, Mataki Y, Maemura K, Natsugoe S.
    • Journal Title

      J Hum Genet.

      Volume: - Issue: 6 Pages: 521-534

    • DOI

      10.1038/s10038-019-0584-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K19945, KAKENHI-PROJECT-18K08626, KAKENHI-PROJECT-18K15219
  • [Journal Article] Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR 145 3p on gene regulation.2019

    • Author(s)
      Shimonosono M, Idichi T, Seki N, Yamada Y, Arai T, Arigami T, Sasaki K, Omoto I, Uchikado Y, Kita Y, Kurahara H, Maemura K, Natsugoe S.
    • Journal Title

      Int J Oncol.

      Volume: 54 Pages: 673-688

    • DOI

      10.3892/ijo.2018.4657

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K10510, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17H04285
  • [Journal Article] Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma2019

    • Author(s)
      Yasutaka Yamada,Takayuki Arai, Mayuko Kato,Satoko Kojima, Shinichi Sakamoto, Akira Komiya, Yukio Naya, Tomohiko Ichikawa, and Naohiko Seki
    • Journal Title

      Am J Clin Exp Urol

      Volume: 7 Pages: 11-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Journal Article] Regulation of KIF2A by Antitumor miR-451a Inhibits Cancer Cell Aggressiveness Features in Lung Squamous Cell Carcinoma2019

    • Author(s)
      Uchida Akifumi、Seki Naohiko、Mizuno Keiko、Yamada Yasutaka、Misono Shunsuke、Sanada Hiroki、Kikkawa Naoko、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
    • Journal Title

      Cancers

      Volume: 11 Issue: 2 Pages: 258-258

    • DOI

      10.3390/cancers11020258

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-18K09338
  • [Journal Article] RNA‐sequence‐based microRNA expression signature in breast cancer: tumor‐suppressive miR‐101‐5p regulates molecular pathogenesis2019

    • Author(s)
      Toda Hiroko、Seki Naohiko、Kurozumi Sasagu、Shinden Yoshiaki、Yamada Yasutaka、Nohata Nijiro、Moriya Shogo、Idichi Tetsuya、Maemura Kosei、Fujii Takaaki、Horiguchi Jun、Kijima Yuko、Natsugoe Shoji
    • Journal Title

      Molecular Oncology

      Volume: 14 Issue: 2 Pages: 426-446

    • DOI

      10.1002/1878-0261.12602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09049, KAKENHI-PROJECT-18K16322
  • [Journal Article] Molecular Pathogenesis of Gene Regulation by the miR-150 Duplex: miR-150-3p Regulates TNS4 in Lung Adenocarcinoma2019

    • Author(s)
      Misono Shunsuke、Seki Naohiko、Mizuno Keiko、Yamada Yasutaka、Uchida Akifumi、Sanada Hiroki、Moriya Shogo、Kikkawa Naoko、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
    • Journal Title

      Cancers

      Volume: 11 Issue: 5 Pages: 601-601

    • DOI

      10.3390/cancers11050601

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09338
  • [Journal Article] Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma2018

    • Author(s)
      Yamada Y, Koshizuka K, Hanazawa T, Kikkawa N, Okato A, Idichi T, Arai T, Sugawara S, Katada K, Okamoto Y, Seki N.
    • Journal Title

      International Journal of Oncology

      Volume: 52 Pages: 166-178

    • DOI

      10.3892/ijo.2017.4190

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229, KAKENHI-PROJECT-18K09338
  • [Journal Article] Impact of novel oncogenic pathways regulated by antitumor miR-451a in renal cell carcinoma2018

    • Author(s)
      Yamada Yasutaka、Arai Takayuki、Sugawara Sho、Okato Atsushi、Kato Mayuko、Kojima Satoko、Yamazaki Kazuto、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      Cancer Sci

      Volume: 印刷中 Issue: 4 Pages: 1239-1253

    • DOI

      10.1111/cas.13526

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-17K16778
  • [Journal Article] Pirin: a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p2018

    • Author(s)
      Arai Takayuki、Kojima Satoko、Yamada Yasutaka、Sugawara Sho、Kato Mayuko、Yamazaki Kazuto、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      Molecular Oncology

      Volume: 13 Issue: 2 Pages: 322-337

    • DOI

      10.1002/1878-0261.12405

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-18K16724, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K11160
  • [Journal Article] Involvement of dual-strand of the miR-144 duplex and their targets in the pathogenesis of lung squamous cell carcinoma2018

    • Author(s)
      Uchida Akifumi、Seki Naohiko、Mizuno Keiko、Misono Shunsuke、Yamada Yasutaka、Kikkawa Naoko、Sanada Hiroki、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 1 Pages: 420-432

    • DOI

      10.1111/cas.13853

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-18K09338
  • [Journal Article] Dual strands of the miR-223 duplex (miR-223-5p and miR-223-3p) inhibit cancer cell aggressiveness: targeted genes are involved in bladder cancer pathogenesis2018

    • Author(s)
      Sugawara Sho、Yamada Yasutaka、Arai Takayuki、Okato Atsushi、Idichi Tetsuya、Kato Mayuko、Koshizuka Keiichi、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      J Hum Genet

      Volume: 印刷中 Issue: 5 Pages: 657-668

    • DOI

      10.1038/s10038-018-0437-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
  • [Journal Article] Downregulation of matrix metalloproteinase 14 by the antitumor miRNA, miR-150-5p, inhibits the aggressiveness of lung squamous cell carcinoma cells2018

    • Author(s)
      Suetsugu Takayuki、Koshizuka Keiichi、Seki Naohiko、Mizuno Keiko、Okato Atsushi、Arai Takayuki、Misono Shunsuke、Uchida Akifumi、Kumamoto Tomohiro、Inoue Hiromasa
    • Journal Title

      International Journal of Oncology

      Volume: 52 Pages: 913-924

    • DOI

      10.3892/ijo.2017.4232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09338
  • [Journal Article] Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance2018

    • Author(s)
      Yamada, Y. Arai, T. Kojima, S. Sugawara, S. Kato, M. Okato, A. Yamazaki, K. Naya, Y. Ichikawa, T. Seki, N.
    • Journal Title

      Cancer Sci

      Volume: 109 (9) Issue: 9 Pages: 2919-2936

    • DOI

      10.1111/cas.13722

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-18K16723, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
  • [Journal Article] Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs.2017

    • Author(s)
      Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Okamoto Y, Seki N.
    • Journal Title

      Oncotarget

      Volume: 印刷中 Issue: 18 Pages: 30288-30304

    • DOI

      10.18632/oncotarget.16327

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
  • [Journal Article] Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma2017

    • Author(s)
      Okato Atsushi、Arai Takayuki、Yamada Yasutaka、Sugawara Sho、Koshizuka Keiichi、Fujimura Lisa、Kurozumi Akira、Kato Mayuko、Kojima Satoko、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 18 Issue: 9 Pages: 1969-1969

    • DOI

      10.3390/ijms18091969

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-17K16778, KAKENHI-PROJECT-16H05462
  • [Journal Article] Involvement of aberrantly expressed microRNAs in the pathogenesis of head and neck squamous cell carcinoma2017

    • Author(s)
      Koshizuka Keiichi、Hanazawa Toyoyuki、Arai Takayuki、Okato Atsushi、Kikkawa Naoko、Seki Naohiko
    • Journal Title

      Cancer Metastasis Rev

      Volume: 36 Issue: 3 Pages: 525-545

    • DOI

      10.1007/s10555-017-9692-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893
  • [Journal Article] Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.2017

    • Author(s)
      Kato M, Kurozumi A, Goto Y, Matsushita R, Okato A, Nishikawa R, Fukumoto I, Koshizuka K, Ichikawa T, Seki N.
    • Journal Title

      Journal of Human genetics

      Volume: 62 Pages: 123-132

    • NAID

      40021036352

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Journal Article] Inhibition of integrin &#x3B2;1-mediated oncogenic signalling by the antitumor <i>microRNA-29</i> family in head and neck squamous cell carcinoma2017

    • Author(s)
      Koshizuka Keiichi、Kikkawa Naoko、Hanazawa Toyoyuki、Yamada Yasutaka、Okato Atsushi、Arai Takayuki、Katada Koji、Okamoto Yoshitaka、Seki Naohiko
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 3 Pages: 3663-3676

    • DOI

      10.18632/oncotarget.23194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
  • [Journal Article] Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma.2017

    • Author(s)
      Koshizuka, K., T. Hanazawa, N. Kikkawa, K. Katada, A. Okato, T. Arai, T. Idichi, Y. Osako, Y. Okamoto and N. Seki
    • Journal Title

      Auris Nasus Larynx

      Volume: - Issue: 4 Pages: 854-865

    • DOI

      10.1016/j.anl.2017.11.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17K16778
  • [Journal Article] Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer2017

    • Author(s)
      Goto Yusuke、Kurozumi Akira、Arai Takayuki、Nohata Nijiro、Kojima Satoko、Okato Atsushi、Kato Mayuko、Yamazaki Kazuto、Ishida Yasuo、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      British Journal of Cancer

      Volume: 117 Issue: 3 Pages: 409-420

    • DOI

      10.1038/bjc.2017.191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-16K20125
  • [Journal Article] Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma.2017

    • Author(s)
      Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Matsushita R, Mataki H, Mizuno K, Okamoto Y, Seki N.
    • Journal Title

      Journal of Human Genetics

      Volume: 62 Issue: 1 Pages: 113-121

    • DOI

      10.1038/jhg.2016.47

    • NAID

      40021036343

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
  • [Journal Article] The microRNA signatures: aberrantly expressed microRNAs in head and neck squamous cell carcinoma.2017

    • Author(s)
      Keiichi Koshizuka, Toyoyuki Hanazawa, Ichiro Fukumoto, Naoko Kikkawa, Yoshitaka Okamoto, Naohiko Seki.
    • Journal Title

      Journal of Human Genetics

      Volume: 62 Issue: 1 Pages: 3-13

    • DOI

      10.1038/jhg.2016.105

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-15K10800
  • [Journal Article] Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer2017

    • Author(s)
      Koshizuka Keiichi、Hanazawa Toyoyuki、Kikkawa Naoko、Arai Takayuki、Okato Atsushi、Kurozumi Akira、Kato Mayuko、Katada Koji、Okamoto Yoshitaka、Seki Naohiko
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 8 Pages: 1681-1692

    • DOI

      10.1111/cas.13298

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
  • [Journal Article] The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes2017

    • Author(s)
      Mizuno Keiko、Mataki Hiroko、Arai Takayuki、Okato Atsushi、Kamikawaji Kazuto、Kumamoto Tomohiro、Hiraki Tsubasa、Hatanaka Kazuhito、Inoue Hiromasa、Seki Naohiko
    • Journal Title

      Journal of Human Genetics

      Volume: 62 Issue: 7 Pages: 671-678

    • DOI

      10.1038/jhg.2017.27

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19458
  • [Journal Article] Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer.2016

    • Author(s)
      Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Matsushita R, Ichikawa T, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 114 Issue: 10 Pages: 1135-1144

    • DOI

      10.1038/bjc.2016.95

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071
  • [Journal Article] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma2016

    • Author(s)
      Ichiro Fukumoto, Naoko Kikkawa, Ryosuke Matsushita, Mayuko Kato, Akira Kurozumi, Rika Nishikawa, Yusuke Goto, Keiichi Koshizuka, Toyoyuki Hanazawa, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Journal Title

      Journal of Human Genetics

      Volume: 61(2) Issue: 2 Pages: 109-118

    • DOI

      10.1038/jhg.2015.120

    • NAID

      40020742209

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596
  • [Journal Article] Regulation of LOXL2 and SERPINH1 by antitumor microRNA-29a in lung cancer with idiopathic pulmonary fibrosis.2016

    • Author(s)
      Kamikawaji K, Seki N, Watanabe M, Mataki H, Kumamoto T, Takagi K, Mizuno K, Inoue H.
    • Journal Title

      J Hum GenetJ Hum Genet.

      Volume: 12 Pages: 985-993

    • NAID

      40021022822

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19458
  • [Journal Article] Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer.2016

    • Author(s)
      Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Matsushita R, Ichikawa T, Seki N.
    • Journal Title

      British journal of cancer

      Volume: 114 Pages: 1135-44

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Journal Article] 新前立腺癌学 -最新の基礎研究と診断・治療- VI. 臨床応用を目指した基礎研究:バイオマーカーの開発:microRNA,2016

    • Author(s)
      26.小島聡子、関直彦
    • Journal Title

      医学書院

      Volume: 74(3) Pages: 201-204

    • Data Source
      KAKENHI-PROJECT-26462430
  • [Journal Article] Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer2016

    • Author(s)
      Okato A, Goto Y, Kurozumi A, Kato M, Kojima S, Matsushita R, Yonemori M, Miyamoto K, Ichikawa T, Seki N.
    • Journal Title

      International journal of oncology

      Volume: 49 Pages: 111-22

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Journal Article] Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer2016

    • Author(s)
      Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
    • Journal Title

      British Journal of Cancer

      Volume: 115 Issue: 3 Pages: 354-363

    • DOI

      10.1038/bjc.2016.179

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
  • [Journal Article] Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer.2016

    • Author(s)
      Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
    • Journal Title

      Cancer Science

      Volume: 107 Issue: 9 Pages: 1233-1242

    • DOI

      10.1111/cas.13002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
  • [Journal Article] The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma.2016

    • Author(s)
      Fukumoto I, Koshizuka K, Hanazawa T, Kikkawa N, Matsushita R, Kurozumi A, Kato M, Okato A, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 49(3) Issue: 3 Pages: 1119-29

    • DOI

      10.3892/ijo.2016.3602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
  • [Journal Article] Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer.2016

    • Author(s)
      Okato A, Goto Y, Kurozumi A, Kato M, Kojima S, Matsushita R, Yonemori M, Miyamoto K, Ichikawa T, Seki N.
    • Journal Title

      Int J Oncol

      Volume: 49 Issue: 1 Pages: 111-122

    • DOI

      10.3892/ijo.2016.3522

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071
  • [Journal Article] MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways.2015

    • Author(s)
      Fukumoto I, Hanazawa T, Kinoshita T, Kikkawa N, Koshizuka K, Goto Y, Nishikawa R, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 112 Issue: 5 Pages: 891-900

    • DOI

      10.1038/bjc.2015.19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-26462596
  • [Journal Article] Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C2015

    • Author(s)
      Mataki H, Enokida H, Chiyomaru T, Mizuno K, Matsushita R, Goto Y, Nishikawa R, Higashimoto I, Samukawa T, Nakagawa M, Inoue H, Seki N.
    • Journal Title

      Journal of Human Genetics

      Volume: 60 Issue: 2 Pages: 53-61

    • DOI

      10.1038/jhg.2014.111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-24659407, KAKENHI-PROJECT-25293192
  • [Journal Article] MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker.2015

    • Author(s)
      Goto Y, Kojima S, Nishikawa R, Kurozumi A, Kato M, Enokida H, Matsushita R, Yamazaki K, Ishida Y, Nakagawa M, Naya Y, Ichikawa T, Seki N
    • Journal Title

      Br J Cancer

      Volume: 113 Issue: 7 Pages: 1055-1065

    • DOI

      10.1038/bjc.2015.300

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071, KAKENHI-PROJECT-25293333
  • [Journal Article] Tumor-suppressive microRNA-218 inhibits cancer cell migration and invasion via targeting of LASP1 in prostate cancer.2014

    • Author(s)
      Nishikawa R, Goto Y, Sakamoto S, Chiyomaru T, Enokida H, Kojima S, Kinoshita T, Yamamoto N, Nakagawa M, Naya Y, Ichikawa T, Seki N.
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 7 Pages: 802-811

    • DOI

      10.1111/cas.12441

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
  • [Journal Article] The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster.2014

    • Author(s)
      Itesako T, Seki N, Yoshino H, Chiyomaru T, Yamasaki T, Hidaka H, Yonezawa T, Nohata N, Kinoshita T, Nakagawa M, Enokida H.
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462490
  • [Journal Article] The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer.2014

    • Author(s)
      Goto Y, Kojima S, Nishikawa R, Enokida H, Chiyomaru T, Kinoshita T, Nakagawa M, Naya Y, Ichikawa T, Seki N.
    • Journal Title

      Oncotarget

      Volume: 5 Pages: 7748-7759

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014

    • Author(s)
      Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol

      Volume: 44 Pages: 2085-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462676
  • [Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer.2014

    • Author(s)
      Kojima S, Enokida H, Yoshino H, Itesako T, Chiyomaru T, Kinoshita T, Fuse M, Nishikawa R, Goto Y, Naya Y, Nakagawa M, Seki N.
    • Journal Title

      J Hum Genet.

      Volume: 59(2) Issue: 2 Pages: 78-87

    • DOI

      10.1038/jhg.2013.121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791636, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
  • [Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer2014

    • Author(s)
      Satoko Kojima, Hideki Enokida, Hirofumi Yoshino, Toshihiko Itesako, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Rika Nishikawa, Yusuke Goto, Yukio Naya, Masayuki Nakagawa and Naohiko Seki
    • Journal Title

      J Hum Genet

      Volume: 59(2) Pages: 78-87

    • NAID

      40019987497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014

    • Author(s)
      Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 44(6) Issue: 6 Pages: 2085-92

    • DOI

      10.3892/ijo.2014.2349

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25861528
  • [Journal Article] 1. Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via2014

    • Author(s)
      Nishikawa R, Goto Y, Kojima S, Enokida H, Chiyomaru T, Kinoshita T, Sakamoto S, Fuse M, Nakagawa M, Naya Y, Ichikawa T, Seki N
    • Journal Title

      Int J Oncol.

      Volume: 45(1) Issue: 1 Pages: 401-410

    • DOI

      10.3892/ijo.2014.2437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791636, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
  • [Journal Article] The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer.2014

    • Author(s)
      Goto Y, Kojima S, Nishikawa R, Enokida H, Chiyomaru T, Kinoshita T, Nakagawa M, Naya Y, Ichikawa T, Seki N.
    • Journal Title

      Oncotarget

      Volume: 5(17) Pages: 7748-7759

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Journal Article] Identification of tumour suppressive microRNA-451a in hypopharyngeal squamous cell carcinoma based on microRNA expression signature2014

    • Author(s)
      Fukumoto I, Kinoshita T, Hanazawa T, Kikkawa N, Chiyomaru T, Enokida H, Yamamoto N, Goto Y, Nishikawa R, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      British Journal of Cancer

      Volume: 111 Issue: 2 Pages: 386-394

    • DOI

      10.1038/bjc.2014.293

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528
  • [Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer.2014

    • Author(s)
      Satoko Kojima, Hideki Enokida, Hirofumi Yoshino, Toshihiko Itesako, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Rika Nishikawa, Yusuke Goto, Yukio Naya, Masayuki Nakagawa and Naohiko Seki.
    • Journal Title

      J Hum Genet.

      Volume: 59(2) Pages: 78-87

    • NAID

      40019987497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Journal Article] Tumour-suppressive microRNA-24-1 inhibits cancer cell proliferation through targeting FOXM1 in bladder cancer.2014

    • Author(s)
      Inoguchi S, Seki N, Chiyomaru T, Ishihara T, Matsushita R, Mataki H, Itesako T, Tatarano S, Yoshino H, Goto Y, Nishikawa R, Nakagawa M, Enokida H.
    • Journal Title

      FEBS letter

      Volume: 588 Issue: 17 Pages: 3170-3179

    • DOI

      10.1016/j.febslet.2014.06.058

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416
  • [Journal Article] Epithelial-mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma.2013

    • Author(s)
      Hirofumi Yoshino, Hideki Enokida, Toshihiko Itesako, Shuichi Tatarano, Takashi Kinoshita, Miki Fuse, Satoko Kojima, Masayuki Nakagawa and Naohiko Seki.
    • Journal Title

      J Hum Genet.

      Volume: 58(8) Issue: 8 Pages: 508-516

    • DOI

      10.1038/jhg.2013.31

    • NAID

      10031195279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592351, KAKENHI-PROJECT-24791636
  • [Journal Article] Tumor-suppressive microRNA-1291 directly regulates glucose transporter 1 in renal cell carcinoma.2013

    • Author(s)
      Yamasaki T, Seki N, Yoshino H, Itesako T, Yamada Y, Tatarano S, Hidaka H, Yonezawa T, Nakagawa M, Enokida H.
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 1411-1419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430137
  • [Journal Article] MicroRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway.2013

    • Author(s)
      Yamasaki T, Seki N, Yoshino H, Itesako T, Hidaka H, Yamada Y, Tatarano S, Yonezawa T, Kinoshita T, Nakagawa M, Enokida H.
    • Journal Title

      Journal of Urology

      Volume: 190 Pages: 1059-2068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430137
  • [Journal Article] The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type-1 and type-2 cells.2013

    • Author(s)
      Tumes, D. J., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., Motohashi, S., and Nakayama, T.
    • Journal Title

      Immunity

      Volume: 39 Issue: 5 Pages: 819-32

    • DOI

      10.1016/j.immuni.2013.09.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790460, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-25860352
  • [Journal Article] Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma.2013

    • Author(s)
      Hirofumi Yoshino, Hideki Enokida, Toshihiko Itesako, Satoko Kojima, Takashi Kinoshita, Shuichi Tatarano, Takeshi Chiyomaru, Masayuki Nakagawa and Naohiko Seki.
    • Journal Title

      Cancer Sci.

      Volume: 104(12) Issue: 12 Pages: 1567-1574

    • DOI

      10.1111/cas.12280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Journal Article] Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma.2013

    • Author(s)
      Yoshino H, Enokida H, Itesako T, Kojima S, Kinoshita T, Tatarano S, Chiyomaru T, Nakagawa M, Seki N.
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 1567-1574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430137
  • [Journal Article] Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma.2013

    • Author(s)
      Yamada Y, Hidaka H, Seki N, Yoshino H, Yamasaki T, Itesako T, Nakagawa M, Enokida H.
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 304-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430137
  • [Journal Article] Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma.2013

    • Author(s)
      Kinoshita T, Nohata N, Hanazawa T, Kikkawa N, Yamamoto N, Yoshino H, Itesako T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 109 Issue: 10 Pages: 2636-2645

    • DOI

      10.1038/bjc.2013.607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25670694, KAKENHI-PROJECT-25861528
  • [Journal Article] Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma.2013

    • Author(s)
      Nohata N, Hanazawa T, Kinoshita T, Inamine A, Kikkawa N, Itesako T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 108 Issue: 8 Pages: 1648-1658

    • DOI

      10.1038/bjc.2013.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592575, KAKENHI-PROJECT-25861528
  • [Journal Article] Epithelial-mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma.2013

    • Author(s)
      Yoshino H, Enokida H, Itesako T, Tatarano S, Kinoshita T, Fuse M, Kojima S, Nakagawa M, Seki N.
    • Journal Title

      Journal of Human Genetics

      Volume: 58 Pages: 1059-1068

    • NAID

      10031195279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430137
  • [Journal Article] Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.2012

    • Author(s)
      Kinoshita T, Nohata N, Fuse M, Hanazawa T, Kikkawa N, Fujimura L, Takano H, Yamada Y, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 418 Pages: 1821-1830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma2012

    • Author(s)
      Moriya Y, Yoshino I, Seki N et al.
    • Journal Title

      Journal of Human Genetics

      Volume: 57 Pages: 38-45

    • NAID

      10030662337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591559
  • [Journal Article] microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.2012

    • Author(s)
      Nohata N, Hanazawa T, Enokida H, Seki N
    • Journal Title

      Oncotarget

      Volume: 3 Pages: 9-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Journal Article] Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma2012

    • Author(s)
      Kinoshita T, Nohata N, Yoshino H, Hanazawa T, Kikkawa N, Fujimura L, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol

      Volume: 40 Pages: 185-93

    • DOI

      10.3892/ijo.2011.1196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
  • [Journal Article] Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma2012

    • Author(s)
      Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
    • Journal Title

      Int. J. Oncol

      Volume: (印刷中) Pages: 1770-8

    • DOI

      10.3892/ijo.2012.1390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790688, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
  • [Journal Article] Tumor suppressive microRNA-133a regulates novel targets : moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma2012

    • Author(s)
      Takashi Kinoshita
    • Journal Title

      Biochemical and biophysical research communications

      Volume: 418 Issue: 2 Pages: 378-83

    • DOI

      10.1016/j.bbrc.2012.01.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
  • [Journal Article] Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.2012

    • Author(s)
      Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 40 Pages: 1770-1778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma.2012

    • Author(s)
      Kinoshita T, Hanazawa T, Nohata N, Kikkawa N, Enokida H, Yoshino H, Yamasaki T, Hidaka H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Oncotarget

      Volume: 3 Pages: 1386-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Journal Article] The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.2012

    • Author(s)
      Kinoshita T, Hanazawa T, Nohata N, Okamoto Y, Seki N
    • Journal Title

      J Hum Genet.

      Volume: 57 Issue: 9 Pages: 556-63

    • DOI

      10.1038/jhg.2012.75

    • NAID

      10031056783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24592590
  • [Journal Article] Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012

    • Author(s)
      Kojima S, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nohata N, Fuse M, Ichikawa T, Naya Y, Nakagawa M, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 106(2) Issue: 2 Pages: 405-413

    • DOI

      10.1038/bjc.2011.462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390420, KAKENHI-PROJECT-23592351, KAKENHI-PROJECT-24592590
  • [Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma.2011

    • Author(s)
      Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
    • Journal Title

      Int J Oncol. 38(1)

      Pages: 209-217

    • Data Source
      KAKENHI-PROJECT-20592011
  • [Journal Article] Mir-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma : correlation with stage and grade, and comparison with urinary cytology.2011

    • Author(s)
      Yasutoshi Yamada, Hideki Enokida, Satoko Kojima, Kazumori Kawakami, Takeshi Chiyomaru, Shuichi Tatarano, Hirofumi Yoshino, Kazuya Kawahara, Kenryu Nishiyama, Naohiko Seki, Masayuki Nakagawa.
    • Journal Title

      Cancer Sci 102(3)

      Pages: 522-529

    • NAID

      10029290902

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Journal Article] LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling.2011

    • Author(s)
      Matsuda R, Enokida H, Chiyomaru T, Kikkawa N, Sugimoto T, Kawakami K, Tatarano S, Yoshino H, Toki K, Uchida Y, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
    • Journal Title

      Br J Cancer. 104

      Pages: 376-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines.2011

    • Author(s)
      Yoshitomi T, Kawakami K, Enokida H, Chiyomaru T, Kagara I, Tatarano S, Yoshino H, Arimura H, Nishiyama K, Seki N, Nakagawa M.
    • Journal Title

      Oncol Rep. 25

      Pages: 1661-1668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer.2011

    • Author(s)
      Tatarano S, Chiyomaru T, Kawakami K, Enokida H, Yoshino H, Hidaka H, Yamasaki T, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
    • Journal Title

      Int J Oncol. 39

      Pages: 13-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011

    • Author(s)
      Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Sasaki K, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
    • Journal Title

      Int J Oncol

      Volume: 39 Pages: 1099-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology.2011

    • Author(s)
      Yamada Y et al.
    • Journal Title

      Cancer Science

      Volume: 102 Issue: 3 Pages: 522-529

    • DOI

      10.1111/j.1349-7006.2010.01816.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501298, KAKENHI-PROJECT-23592351
  • [Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011

    • Author(s)
      Nijiro Nohata
    • Journal Title

      British journal of cancer

      Volume: 105 Issue: 6 Pages: 833-41

    • DOI

      10.1038/bjc.2011.311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
  • [Journal Article] Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC)2011

    • Author(s)
      Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Sakurai D, Fujimura L, Kawakami K, Chiyomaru T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
    • Journal Title

      J Hum Genet

      Volume: 56 Pages: 595-601

    • NAID

      40018947302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma2011

    • Author(s)
      Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
    • Journal Title

      Int J Oncol

      Volume: 38 Pages: 209-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma : correlation with stage and grade, and comparison with urinary cytology.2011

    • Author(s)
      Yamada Y, Enokida H, Kojima S, Kawakami K, Chiyomaru T, Tatarano S, Yoshino H, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
    • Journal Title

      Cancer Sci. 102

      Pages: 522-529

    • NAID

      10029290902

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] MiR-133a induces apoptosis through direct regulation of GSTP1 in bladder cancer cell lines.2011

    • Author(s)
      Uchida Y, Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
    • Journal Title

      Urol Oncol. [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011

    • Author(s)
      Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Fujimura L, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Katayama A, Harabuchi Y, Okamoto Y, Seki N
    • Journal Title

      Br J Cancer

      Volume: 105 Pages: 833-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1.2011

    • Author(s)
      Miki Fuse, Nijiro Nohata, Satoko Kojima, Shinichi Sakamoto, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Journal Title

      Int.J.Oncol. 38

      Pages: 1093-1011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Journal Article] The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer.2011

    • Author(s)
      Yoshino H, Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Nishiyama K, Nohata N, Seki N, Nakagawa M.
    • Journal Title

      Br J Cancer. 104

      Pages: 808-818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma2011

    • Author(s)
      Nohata N, Sone Y, Hanazawa T, Fuse M, Kikkawa N, Yoshino H, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Shozu M, Okamoto Y, Seki N
    • Journal Title

      Oncotarget

      Volume: 2 Pages: 29-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] 前立腺がんにおけるマイクロRNA発現プロファイル2011

    • Author(s)
      小島聡子、納谷幸男、市川智彦、関直彦
    • Journal Title

      日本臨床 増刊号 前立腺癌(第2版)

      Volume: 24(8) Pages: 92-95

    • Data Source
      KAKENHI-PROJECT-23592351
  • [Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011

    • Author(s)
      Nijiro Nohata
    • Journal Title

      International journal of oncology

      Volume: 39 Pages: 1099-107

    • DOI

      10.3892/ijo.2011.1096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
  • [Journal Article] miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer.2010

    • Author(s)
      Chiyomaru T, Enokida H, Tatarano S, Kawahara K, Uchida Y, Nishiyama K, Fujimura L, Kikkawa N, Seki N, Nakagawa M.
    • Journal Title

      Br J Cancer. 102

      Pages: 883-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)2010

    • Author(s)
      Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N
    • Journal Title

      Br J Cancer

      Volume: 103 Pages: 877-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Journal Article] マイクロRNA(miR-145、miR-133a・b)の頭頸部扁平上皮癌における増殖・浸潤抑制機能と標的遺伝子の同定2010

    • Author(s)
      花澤豊行, 吉川直子, 野畑二次郎, 堅田浩司, ムラディル・ムラリフ, 鈴木誉, 佐々木慶太, 茶薗英明, 堀口茂俊, 岡本美孝, 関直彦
    • Journal Title

      頭頸部癌 36(1)

      Pages: 1-8

    • NAID

      10029079202

    • Data Source
      KAKENHI-PROJECT-20592011
  • [Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC).2010

    • Author(s)
      Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer. 7;103(6)

      Pages: 877-884

    • Data Source
      KAKENHI-PROJECT-20592011
  • [Journal Article] Identification of novel microRNA targets based on microRNA signatures in bladder cancer.2009

    • Author(s)
      Ichimi T, Enokida H, Okuno Y, Kunimoto R, Chiyomaru T, Kawamoto K, Kawahara K, Toki K, Kawakami K, Nishiyama K, Tsujimoto G, Nakagawa M, Seki N.
    • Journal Title

      Int J Cancer. 125

      Pages: 345-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Journal Article] Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer2009

    • Author(s)
      Moriya Y, Iyoda A, Kasai Y, Sugimoto T, Hashida J, Nimura Y, Kato M, Takiguchi M, Fujisawa T, Seki N, Yoshino I
    • Journal Title

      Lung Cancer 64

      Pages: 86-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591610
  • [Journal Article] The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.2009

    • Author(s)
      Sugimoto T, Seki N, Shimizu S, Kikkawa N, Tsukada J, Shimada H, Sasaki K, Hanazawa T, Okamoto Y, Hata A
    • Journal Title

      Genes Chromosomes Cancer. 48(2)

      Pages: 132-142

    • Data Source
      KAKENHI-PROJECT-20592011
  • [Journal Article] Identification of a novel therapeutic target for head and neck squamous cell carcinomas : A role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway.2008

    • Author(s)
      Shimizu S, Tsukada J, Sugimoto T, Kikkawa N, Sasaki K, Chazono H, Hanazawa T, Okamoto Y, Seki N
    • Journal Title

      Int J Cancer. 15;123(8)

      Pages: 1816-1823

    • Data Source
      KAKENHI-PROJECT-20592011
  • [Journal Article] Identification of differentially expressed genes in human bladder cancer through genome-wide gene expression profiling2006

    • Author(s)
      Kawakami K, Enokida H, Tachiwada T, Gotanda T, Tsuneyoshi K, Kubo H, Nishiyama K, Takiguchi M, Nakagawa, M, Seki N.
    • Journal Title

      Oncology Reports (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591603
  • [Journal Article] WISP-2 expression in human salivary gland tumors2006

    • Author(s)
      Kouzu Y, Uzawa K, Kato M, Higo M, Nimura Y, Harada K, Numata T, Seki N, Sato M, Tanzawa H
    • Journal Title

      Int J Mol Med 17

      Pages: 567-573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209059
  • [Journal Article] Identification of candidate radioresistant genes in human squamous cell carcinoma cells through gene expression analysis using DNA microarrays.2005

    • Author(s)
      Higo M, Uzawa K, Kouzu Y, Bukawa H, Nimura Y, Seki N, Tanzawa H.
    • Journal Title

      Oncol Rep. 14

      Pages: 1293-1298

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591189
  • [Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003

    • Author(s)
      Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M
    • Journal Title

      Int J Mol Med. 12

      Pages: 429-435

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390608
  • [Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003

    • Author(s)
      Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M, Tanzawa H.
    • Journal Title

      Int J Mol Med 12

      Pages: 429-435

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390608
  • [Patent] microRNA発現プロファイリングに基づく尿路上皮癌の検出方法2010

    • Inventor(s)
      関直彦、榎田英樹、中川昌之
    • Industrial Property Rights Holder
      国立大学法人千葉大学、国立大学法人鹿児島大学
    • Industrial Property Number
      2010-159384
    • Filing Date
      2010-07-14
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Patent] microRNA発現プロファイリングに基づく膀胱癌の検出方法2009

    • Inventor(s)
      関直彦, 中川昌之
    • Industrial Property Rights Holder
      千葉大学、鹿児島大学
    • Patent Publication Number
      2009-100687
    • Filing Date
      2009-05-14
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Patent] microRNA発現プロファイリングに基づく尿路上皮癌の検出方法2007

    • Inventor(s)
      関直彦、榎田英樹、中川昌之
    • Industrial Property Rights Holder
      国立大学法人千葉大学、国立大学法人鹿児島大学
    • Industrial Property Number
      2007-276191
    • Filing Date
      2007-10-24
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] 癌抑制型microRNA-144 の制御する腎癌分子ネットワークの探索2019

    • Author(s)
      山田康隆、菅原翔、新井隆之、岡東篤、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第107回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 転移性前立腺癌における遠隔リンパ節の予後因子としての重要性2019

    • Author(s)
      小島聡子、加藤智規、増田広、荒木千裕、巣山貴仁、芳生旭辰、大塚耕太郎、三神功亮、関根啓太、納谷幸男
    • Organizer
      第107回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型マイクロRNA-99a-3p を起点とした去勢抵抗性前立腺癌・治療標的分子の探索2019

    • Author(s)
      新井隆之、小島聡子、山田康隆、菅原翔、岡東篤、納谷幸男、市川智彦、関直彦
    • Organizer
      第107回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型 microRNA-451a の制御する腎癌分子ネットワークの探索2018

    • Author(s)
      山田 康隆、菅原 翔、新井 隆之、岡東 篤、 小島 聡子、納谷 幸男、市川 智彦、関 直彦
    • Organizer
      第 106 回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] Antitumor miR-451a regulatory network is associated with poor prognosis of renal cell carcinoma2018

    • Author(s)
      Y. Yamada, S. Sugawara, T. Arai, A. Okato, S. Kojima, Y. Naya, T. Ichikawa, N. Seki.
    • Organizer
      AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型マイクロ RNA(miR-10a-5p) が制御する治療抵抗性腎癌・新規分子ネットワークの探索2018

    • Author(s)
      新井 隆之、岡東 篤、小島 聡子、黒住 顕、 加藤 繭子、納谷 幸男、市川 智彦、関 直彦
    • Organizer
      第 106 回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型マイクロRNAにより制御される細胞周期関連遺伝子NCAPGは、去勢知恵構成前立腺癌の治療法的分子である2018

    • Author(s)
      新井隆之、岡東篤、山田康隆、菅原翔、黒住顕、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第27回 泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] Regulation of NCAPG by miR-99a-3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC2018

    • Author(s)
      T. Arai, A. Okato, Y. Yamada, S. Sugawara, A. Kurozumi, S. Kojima, Y. Naya, T. Ichikawa, N. Seki.
    • Organizer
      AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 腎細胞癌・マイクロ RNA 発現プロファイルに基づく、機能性 RNA ネットワークの探索2018

    • Author(s)
      岡東 篤、新井 隆之、山田 康隆、菅原 翔、 黒住 顕、加藤 繭子、小島 聡子、納谷 幸男、 市川 智彦、関 直彦
    • Organizer
      第 106 回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型microRNA-451の制御する腎癌分子ネットワークの探索2018

    • Author(s)
      山田康隆、菅原翔、新井隆之、岡東篤、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第27回 泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 治療抵抗性腎癌細胞で発現低下を認めるmiR-10aの機能解析と新規機能性RNA分子ネットワークの探索2017

    • Author(s)
      新井隆之、五島悠介、岡東篤、黒住顕、加藤繭子、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第105回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 癌抑制型microRNA-320aが制御する前立腺癌分子ネットワークの探索2017

    • Author(s)
      岡東篤、五島悠介、黒住顕、加藤繭子、新井隆之、小島聡子、市川智彦、関直彦
    • Organizer
      第105回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 新規癌抑制型マイクロRNA(miR-145-3p)を基点とした去勢抵抗性前立腺癌・治療標的分子の探索2017

    • Author(s)
      黒住顕、五島悠介、野畑二次郎、小島聡子、新井隆之、岡東篤、加藤繭子、納谷幸男、市川智彦、関直彦
    • Organizer
      第26回泌尿器科分子・細胞研究会
    • Place of Presentation
      全労済ソレイユ (大分)
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly regulate metastasis-promoting LOXL2 in prostate cancer2017

    • Author(s)
      Mayuko Kato, Akira Kurozumi, Yusuke Goto, Ryosuke Matsushita, Ichiro Fukumoto, Atsushi Okato, Rika Nishikawa, Shinichi Sakamoto, Tomohiko Ichikawa, Naohiko Seki
    • Organizer
      American Association for Cancer Research Annual meeting 2016
    • Place of Presentation
      Ernest N. Morial Convention Center New Orleans, Louisiana, USA
    • Year and Date
      2017-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Presentation] Impact of antitumore microRNA-145-3p regulated RNA networks in castration-resistant prostate cancer.2017

    • Author(s)
      Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Satoko Kojima, Takayuki Arai, Atsushi Okato, Mayuko Kato, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Urology Association 2017 in Boston
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] MicroRNA expression signature of patients with tyrosine kinase inhibitors failure: miR-10a-5p inhibits cancer cell aggressiveness in renal cell carcinoma.2017

    • Author(s)
      Takayuki Arai, Atsushi Okato, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Keiichi Koshizuka, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] miR-150前駆体から派生する2種類のマイクロRNA(miR-150-5p, miR-150-3p)は前立腺癌において癌抑制機能を有する2017

    • Author(s)
      岡東篤、新井隆之、黒住顕、加藤繭子、五島悠介、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第26回泌尿器科分子・細胞研究会
    • Place of Presentation
      全労済ソレイユ (大分)
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) are involved in castration-resistant prostate cancer pathogenesis.2017

    • Author(s)
      Mayuko Kato, Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Takayuki Arai, Atsushi Okato, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 前立腺癌ゲノムシークエンスにより明らかとなった新規癌抑制型マイクロRNA (miR-150-5p/miR-150-3p)の機能解析2017

    • Author(s)
      岡東篤、五島悠介、黒住顕、加藤繭子、新井隆之、小島聡子、市川智彦、関直彦
    • Organizer
      第105回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] TKI治療抵抗性腎細胞癌・マイクロRNA発現プロファイル:microRNA-10a-5pの機能解析と標的分子の探索2017

    • Author(s)
      新井隆之、岡東篤、黒住顕、加藤繭子、五島悠介、小島聡子、納谷幸男、市川智彦、関直彦
    • Organizer
      第26回泌尿器科分子・細胞研究会
    • Place of Presentation
      全労済ソレイユ (大分)
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] 前立腺疾患機能性RNA解析に基づく前立腺癌特異的分子ネットワークの探索2017

    • Author(s)
      岡東篤、小島聡子、市川智彦、関直彦
    • Organizer
      第33回前立腺シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] 次世代シークエンサーを用いた頭頸部扁平上皮癌・マイクロRNA発現プロファイルに基づく新規癌抑制型マイクロRNAの探索2017

    • Author(s)
      吉川直子 越塚慶一 花澤豊行 福本一郎 岡本美孝 関直彦
    • Organizer
      第41回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-16K11224
  • [Presentation] Impact of microRNA expression signature of patients with TKI failure:regulation of miR-10a-5p pathways in renal cell carcinoma.2017

    • Author(s)
      Takayuki Arai, Atsushi Okato, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Urology Association 2017 in Boston
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] Dual-strands pre-microRNA-150 (miR-150-5p and miR-150-3p) acts as tumor suppressor in prostate cancer.2017

    • Author(s)
      Atsushi Okato, Takayuki Arai, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] miR-452 inhibits migration and invasion of prostate cancer cells by targeting E3 ubiquitin ligase-1 (WWP1).2017

    • Author(s)
      Satoko Kojima, Yusuke Goto, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Takayuki Arai, Tomohiko Ichikawa, Yukio Naya, Naohiko Seki.
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] Tumor-suppressive microRNA-26a-5p/-26b-5p inhibit cancer cell migration and invasion through targeting PLOD2 that is a potential prognostic maker in bladder cancer.2017

    • Author(s)
      Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Sakaguchi T, Sugita S, Enokida H, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Boston (USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293354
  • [Presentation] The microRNA expression signature of patients with renal cell carcinoma: Tumor suppressive miR-149-5p targeting FOXM1.2017

    • Author(s)
      Atsushi Okato, Takayuki Arai, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Urology Association 2017 in Boston
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11160
  • [Presentation] Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) are involved in castration-resistant prostate cancer pathogenesis2017

    • Author(s)
      Mayuko Kato, Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Takayuki Arai, Atsushi Okato, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Presentation] 機能性RNAネットワークの解析に基づく去勢抵抗性前立腺癌治療標的分子の同定2016

    • Author(s)
      黒住顕、五島悠介、小島聡子、市川智彦、関直彦
    • Organizer
      第32回前立腺シンポジウム
    • Place of Presentation
      東京コンファレンスセンター (品川)
    • Year and Date
      2016-12-10
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] 頭頸部扁平上皮癌において癌抑制型miR-1/206はEGFRとc-METを制御する.2016

    • Author(s)
      11.越塚 慶一, 花澤 豊行, 福本 一郎, 吉川 直子, 松下 良介, 俣木 浩子, 水野 圭子, 岡本 美孝, 関 直彦.
    • Organizer
      第75回日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-26462596
  • [Presentation] Dual-strands of microRNA-139 (miR-139-5p and miR-139-3p) targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016

    • Author(s)
      Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K11015
  • [Presentation] Identification of dual tumorsuppressors (miR-225p/miR-223p) based on microRNA expression signature by deep sequencing of CRPC.2016

    • Author(s)
      Yusuke Goto, Satoko Kojima, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Yukio Naya, Hideki Enokida, Ryosuke Matsushita, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Urology Association
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2016-05-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Dual tumor-suppressors (miR-145-5p/miR-145-3p) inducing cancer cell apoptosis via direct targeting UHRF1 in bladder cancer2016

    • Author(s)
      Matsushita R, Seki N, Yoshino H, Miyamoto K, Yonemori M, Kurozumi A, Goto Y, Enokida H, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      San Diego (USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293354
  • [Presentation] 全ゲノムCRPC機能性RNA発現解析に基づくCRPC活性化分子経路の探索2016

    • Author(s)
      五島悠介、小島聡子、松下良介、黒住顕、加藤繭子、西川里佳、坂本信一、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
    • Organizer
      第104回日本泌尿器科学会総会
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2016-04-23
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Tumor suppressive miRNA-26a/b inhibit cell migration and invasion through targeting a prognostic marker, Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) in bladder cancer.2016

    • Author(s)
      Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
    • Organizer
      第68回西日本泌尿器科学会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2016-11-24
    • Data Source
      KAKENHI-PROJECT-16K11015
  • [Presentation] Regulation of UHRF1mediated pathways by tumorsuppressive microRNA101 in molecular targeted therapy resistant renal cell carcinoma.2016

    • Author(s)
      Yusuke Goto, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Satoko Kojima, Ryosuke Matsushita, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Urology Association
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2016-05-06
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Dual tumor-suppressors miR-139-5p/-3p derived from pre-miR-139 via targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016

    • Author(s)
      Yonemori M, Seki N, Matsushita R, Miyamoto K, Yoshino H, Goto Y, Kato M, Kurozumi A, Nakagawa M, Enokida H
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      San Diego (USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293354
  • [Presentation] microRNA-320aはLAMP1の発現を抑制して前立腺癌細胞の遊走・浸潤を制御する2016

    • Author(s)
      岡東篤、五島悠介、黒住顕、加藤繭子、小島聡子、坂本信一、松下良介、榎田英樹、中川昌之、市川智彦、関直彦
    • Organizer
      第25回泌尿器科分子・細胞研究会
    • Place of Presentation
      ハイアットリージェンシー大阪(大阪府大阪市)
    • Year and Date
      2016-02-26
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] 全ゲノムシークエンス解析によって明らかとなった去勢抵抗性前立腺癌・癌抑制型マイクロRNAクラスター(miR-221/222)の機能解析2016

    • Author(s)
      五島悠介、黒住顕、小島聡子、加藤繭子、岡等篤、坂本信一、松下良介、榎田英樹、中川昌之、市川智彦、関直彦
    • Organizer
      第25回泌尿器科分子・細胞研究会
    • Place of Presentation
      ハイアットリージェンシー大阪(大阪府大阪市)
    • Year and Date
      2016-02-26
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Identification of dual tumor-suppressors (miR-222-5p/miR-222-3p) based on microRNA expression signature by deep sequencing of CRPC.2016

    • Author(s)
      Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Sakamoto S, Naya Y, Enokida H, Matsushita R, Nakagawa M, Ichikawa T, Seki N.
    • Organizer
      AUA annual meeting 2016
    • Place of Presentation
      San Diego Convention Center, San Diego, 米国 カリフォルニア州
    • Year and Date
      2016-05-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05462
  • [Presentation] Dual tumor-suppressors (miR-145-5p/miR-145-3p) inducing cancer cell apoptosis via direct targeting UHRF1 in bladder cancer2016

    • Author(s)
      Matsushita R, Seki N, Yoshino H, Miyamoto K, Yonemori M, Kurozumi A, Goto Y, Enokida H, and Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      San Diego(USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462416
  • [Presentation] Targeting multiple functions of E3 ubiquitin ligase-1 (WWP1) signaling by miR-452 inhibits cancer cell migration and invasion in prostate cancer.2015

    • Author(s)
      Goto Y, Kurozumi A, Nishikawa R, Kato M, Sakamoto S, Kojima S, Naya Y Enokida H, Nakagawa M, Ichikawa T, Seki N.
    • Organizer
      AUA annual meeting 2015
    • Place of Presentation
      New Orleans Morial Convention Center, New Orleans, 米国 ルイジアナ州
    • Year and Date
      2015-05-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] GOLM1は複数の癌抑制型microRNAによって制御される前立腺癌の新規癌遺伝子である2015

    • Author(s)
      五島悠介、小島聡子、黒住顕、西川里佳、加藤繭子、千代丸剛、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
    • Organizer
      第103回日本泌尿器科学会総会
    • Place of Presentation
      ホテル日航金沢(石川県、金沢市)
    • Year and Date
      2015-04-18
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] 去勢抵抗性前立腺癌マイクロRNA発現プロファイルに基づく新規分子ネットワークの解析.2015

    • Author(s)
      小島聡子、五島悠介、西川里佳、黒住顕、千代丸剛、榎田英樹、中川昌之、市川智彦、山崎一人、石田康生、関直彦、納谷幸男
    • Organizer
      第103回日本泌尿器科学会総会
    • Place of Presentation
      ホテル日航金沢(石川県、金沢市)
    • Year and Date
      2015-04-18
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] CRPC臨床検体を用いた機能性RNA発見解析に基づくCRPC治療標的活性化経路の探索2015

    • Author(s)
      五島悠介、小島聡子、市川智彦、関直彦
    • Organizer
      第31回前立腺シンポジウム
    • Place of Presentation
      東京コンファレンスセンター・品川(東京都、港区)
    • Year and Date
      2015-12-12
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] 去勢抵抗性前立腺癌マイクロRNA発現プロファイルに基づいた癌抑制型miR-22/222クラスターの機能解析2015

    • Author(s)
      五島悠介、小島聡子、西川里佳、松下良介、福本一郎、坂本信一、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県、名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Targeting multiple functions of E3 ubiquitin ligase-1 (WWP1) signaling by miR-452 inhibits cancer cell migration and invasion in prostate cancer.2015

    • Author(s)
      Yusuke Goto, Akira Kurozumi, Rika Nishikawa, Mayuko Kato, Shinichi Sakamoto, Satoko Kojima, Yukio Naya, Hideki Enokida, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      AUA 2015 (米国泌尿器科学会)
    • Place of Presentation
      ニューオーリンズ(アメリカ合衆国)
    • Year and Date
      2015-05-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Tumor suppressive microRNA-218 inhibites cancer cell migration and invasion via targeting LASP1 in prostate cancer2014

    • Author(s)
      Nishikawa R, Goto Y, Kinoshita T, Sakamoto S, Chiyomaru T, Enokida H, Kojima S, Nakagawa M, Naya Y, Ichikawa T, Seki N.
    • Organizer
      AACR 2014 annual meeting
    • Place of Presentation
      San Diego Convention Center (San Diego, USA)
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] 癌抑制型microRNAによって制御されるGOLM1は前立腺癌の新規癌遺伝子である2014

    • Author(s)
      西川里佳、五島悠介、坂本信一、千代丸 剛、榎田英樹、小島聡子、中川昌之、納谷幸男、市川智彦、関 直彦
    • Organizer
      第23回泌尿器科分子・細胞研究会
    • Place of Presentation
      山形テルサ(山形県山形市)
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] 複数の癌抑制型microRNAによって制御されるGOLM1は前立腺癌の新規癌遺伝子である2014

    • Author(s)
      五島悠介、西川里佳、坂本信一、千代丸 剛、榎田英樹、小島聡子、中川昌之、納谷幸男、市川智彦、関 直彦
    • Organizer
      第23回泌尿器科分子・細胞研究会
    • Place of Presentation
      山形テルサ(山形県山形市)
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] 下咽頭癌においてmiR-504はCDK6の制御を介して細胞増殖を抑制する2014

    • Author(s)
      吉川直子 花澤豊行 木下崇 福本一郎 岡本美孝 関直彦
    • Organizer
      第38回 日本頭頸部癌学会
    • Place of Presentation
      東京ファッションタウンビル(東京都江東区)
    • Year and Date
      2014-06-12
    • Data Source
      KAKENHI-PROJECT-25462676
  • [Presentation] 癌抑制型microRNAが制御する前立腺癌転移機構の解明2013

    • Author(s)
      五島悠介、西川里佳、坂本信一、小島聡子、市川智彦、関 直彦
    • Organizer
      第29回前立腺シンポジウム
    • Place of Presentation
      東京コンファレンスセンター品川(東京都港区)
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] Expression signature of tumor-suppressive miRNA and control of cancer associated molecular pathways in prostate cancer.2013

    • Author(s)
      5) Satoko Kojima, Hideki Enokida, Hirohumi Yoshino, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Yukio Naya, Masayuki Nakagawa, Naohiko Seki
    • Organizer
      第104回AUA Annual Meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Expression signature of tumor-suppressive miRNA and control of cancer associated molecular pathways in prostate cancer2013

    • Author(s)
      Satoko Kojima, Hideki Enokida, Hirohumi Yoshino, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Yukio Naya, Masayuki Nakagawa, Naohiko Seki
    • Organizer
      第104回AUA Annual Meeting 2013
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma2013

    • Author(s)
      Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Noriko Yamamoto, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      AACR Annual 104th Meeting
    • Place of Presentation
      Washington, DC, USA)
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] Identification of pureine nucleoside phosphorylase (PNP) as a novel target of tumor suppressors miR-1 and MiR-133a in prostate cancer2012

    • Author(s)
      Satoko Kojima, Takeshi Chiyomaru, Hirofumi Yoshino, Hideki Enokida, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
    • Organizer
      第103回AUA annual meeting
    • Place of Presentation
      Atlanta, GA USA(Abstract No 487)
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012

    • Author(s)
      Satoko Kojima, Takeshi Chiyomaru, Hideki Enokida, Kazumori Kawakami, Hirofumi Yoshino, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
    • Organizer
      27^<th> EAU
    • Place of Presentation
      Paris(abstract No 842)
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature2012

    • Author(s)
      Toyoyuki Hanazawa, Nijiro Nohata, Takashi Kinoshita,Naoko Kikkawa,Miki Fuse, Takeshi Chiyomaru, Hirofumi Yoshinoi, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      AACR 103rd Annual Meeting
    • Place of Presentation
      Chicago, IL, USA
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] 前立腺癌におけるmicro-RNA発現プロファイルと遺伝子制御の探索2012

    • Author(s)
      小島聡子、布施美樹、千代丸剛、野畑二次郎、木下崇、吉野裕史、榎田英樹、中川昌之、市川智彦、納谷幸男、関直彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012

    • Author(s)
      花澤豊行、野畑二次郎、木下崇、吉川直子、堅田浩司、茶薗英明、岡本美孝、関直彦
    • Organizer
      第36回日本頭頸部癌学会学術講演会
    • Place of Presentation
      島根県民会館島根
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] MicroRNAs detection in urine as diagnostic markers and predictors of recurrence of non-muscle invasive bladder cancer.2012

    • Author(s)
      Hideki Enokida, Yasutoshi Yamada, Hirofumi Yoshino, Shuichi Tatarana, Hideo Hidaka, Takeshi Yamasaki, Takeshi Chiyomaru, Satoko Kojima, Naohiko Seki, Masayuki Nakagawa.
    • Organizer
      第103回 米国泌尿器科学会AUA annual meeting
    • Place of Presentation
      アトランタ
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Tumor suppressive microRNA-1 and microRNA-133a cluster regulating molecular targets in head and neck squamous cell carcinoma2012

    • Author(s)
      Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Daiju Sakurai, Miki Fuse, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      8th International Conference on Head and Neck Cancer
    • Place of Presentation
      Toronto, ON, Canada
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012

    • Author(s)
      Satoko Kojima, Takeshi Chiyomaru, Hideki Enokida, Kazumori Kawakami, Hirofumi Yoshino,Nijiro Nohata3, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
    • Organizer
      27th Annual EAU congress
    • Place of Presentation
      Paris France
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Identification of pureine nucleoside phosphorylase (PNP) as a novel target of tumor suppressors miR-1 and MiR-133a in prostate cancer.2012

    • Author(s)
      Satoko Kojima, Takeshi Chiyomaru, Hirofumi Yoshino, Hideki Enokida, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
    • Organizer
      第103回 米国泌尿器科学会AUA annual meeting
    • Place of Presentation
      アトランタ
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012

    • Author(s)
      花澤豊行、 野畑二次郎、 木下崇、 吉川直子、 堅田浩司、 茶薗英明、 岡本美孝、関直彦
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      島根県民会館(島根)
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] Tumor suppressive microRNA-1/-133a regulates multiple oncogenes in maxillary sinus squamous cell carcinoma2011

    • Author(s)
      Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Muradil Mutallip, Takeshi Chiyomaru, Kazumori Kawakami, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Presentation] The tumor suppressive miRNA cluster of miR-1 and miR-133a targets oncogenic TAGLN2 gene in bladder cancer.2011

    • Author(s)
      Yoshino H, Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2011-05-16
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] 前立腺癌におけるmiR-1およびmiR-133aの機能解析と標的遺伝子PNPの同定2011

    • Author(s)
      小島聡子、千代丸剛、川上一盛、榎田英樹、野畑二次郎、布施美樹、吉野裕史、稲原昌彦、中川昌之、納谷幸男、関直彦
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      京都(P-2101)
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] Functional role of LASP1 in bladder cancer cell viability and its regulation by microRNAs.2011

    • Author(s)
      Chiyomaru T, Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2011-05-15
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] Identification of tumor suppressive micro RNAs in maxillary sinus squamous cell carcinoma based on micro RNA expression signature2011

    • Author(s)
      Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      AACR 102nd Annual Meeting
    • Place of Presentation
      Orlando, Florida
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Presentation] miR-218 on the genomic loss region of chromosome 4P15.31 functions as a tumor suppressor in bladder cancer.2011

    • Author(s)
      Tatarano S, Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2011-05-15
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] miR-133a as a tumor suppressive microRNA targeting multiple oncogenes in head neck squamous cell carcinoma2011

    • Author(s)
      Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Miki Fuse, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      AACR 102nd Annual Meeting
    • Place of Presentation
      Orlando, Florida
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Presentation] Tumor suppressive microRNA-375 targeting multiple oncogenes in maxillary sinus squamous cell carcinoma (MSSCC)2011

    • Author(s)
      Takashi Kinoshita, Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Mutallip Muradil, Hirofumi Yoshino, Kazumori Kawakami, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場名古屋
    • Data Source
      KAKENHI-PROJECT-21592187
  • [Presentation] Identification of tumor suppressive microRNAs in maxillary sinus squamous cell carcinoma based on microRNA expression signature2011

    • Author(s)
      Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
    • Organizer
      AACR 102nd Annual Meeting
    • Place of Presentation
      Orlando, Florida, USA
    • Data Source
      KAKENHI-PROJECT-23592505
  • [Presentation] 前立腺癌におけるmiR-1およびmiR-133aの機能解析と標的遺伝子PNPの同定2011

    • Author(s)
      小島聡子、千代丸剛、川上一盛、榎田英樹、野畑二次郎、布施美樹、吉野裕史、稲原昌彦、中川昌之、納谷幸男、関直彦
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23592351
  • [Presentation] MicroRNAs (miR-96 and miR-183) detection serves as urine markers in patients with urothelial carcinoma.2011

    • Author(s)
      Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2011-05-15
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines.2011

    • Author(s)
      Yoshitomi T, Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2011-05-16
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] 前立腺癌におけるmiR-200 familyおよびmiR-205の機能解析2010

    • Author(s)
      小島聡子、榎田英樹、千代丸剛、中川昌之、稲原昌彦、納谷幸男、関直彦
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Presentation] 進行前立腺癌におけるmicroRNAのプロファイル解析2010

    • Author(s)
      小島聡子、榎田英樹、千代丸剛、稲原昌彦、中川昌之、納谷幸男、関直彦
    • Organizer
      第19回泌尿器分子・細胞研究会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Presentation] MiR-133a functions as a tumor suppressor and directly regulates GSTP1 expression in bladder cancer.2010

    • Author(s)
      Uchida Y, Enokida H, Seki N, Nakagawa M.
    • Organizer
      American Urological Association (AUA) annual meeting.
    • Place of Presentation
      San Francisco
    • Year and Date
      2010-05-31
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] miR-145 and miR-133a function as tumor suppressors and directly regulate FSCN1 expression in bladder cancer.2010

    • Author(s)
      Chiyomaru T, Enokida H, Seki N, Nakagawa M.
    • Organizer
      European Association of Urology (EAU) annual meeting
    • Place of Presentation
      Barcelona
    • Year and Date
      2010-04-19
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation]2009

    • Author(s)
      Satoko Kojima, Ryoko Watanabe, Jun Tsukada, Yuzo Furuya, Naohiko Seki.
    • Organizer
      The 100^<th> AUA annual meeting MiR-15a functions as a tumor suppressor for prostate cancer by targeting multiple oncogenes.
    • Place of Presentation
      Chicago, Illinois, USA.
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Presentation] MiR-15a functions as a tumor suppressor for prostate cancer by targeting multiple oncogenes.2009

    • Author(s)
      Satoko Kojima, Ryoko Watanabe, Jun Tsukada, Yuzo Furuya, Naohiko Seki
    • Organizer
      EUA The 24^<th> annual congress of European association of urology, 17-21 march 2009 Stockholm, Sweden Abstract 777.
    • Place of Presentation
      Stockholm, Sweden.
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Presentation] 進行前立腺癌におけるmicroRNAの発現解析2009

    • Author(s)
      小島聡子、有馬雅史、榎田英樹、千代丸剛、中川昌之、稲原昌彦、関直彦
    • Organizer
      第68回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21791530
  • [Presentation] Identification of differentially expressed mature microRNAs in bladder cancer.2008

    • Author(s)
      Enokida H, Seki N, Nakagawa M.
    • Organizer
      23rd Annual European Association of Urology Congress(EAU)
    • Place of Presentation
      Milan
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-20390427
  • [Presentation] The functional significance and its regulated molecular targets of microRNA-23b/27b/24-1 cluster in prostate cancer.

    • Author(s)
      Goto Y, Nishikawa R, Kojima S, Sakamoto S, Kawamura K, Imamoto T, Chiyomaru T, Enokida H, Kinoshita T, Naya Y, Nakagawa M, Ichikawa T, Seki N.
    • Organizer
      American Urological Association annual meeting 2014
    • Place of Presentation
      米国フロリダ州オーランド市 Orange County Convention Center
    • Year and Date
      2014-05-16 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25293333
  • [Presentation] マイクロRNA-143/145クラスターは前立腺癌において、GOLM1を標的とし、癌抑制遺伝子として機能する

    • Author(s)
      小島聡子、榎田英樹、吉野裕史、井出迫俊彦、千代丸剛、木下崇、五島悠介、布施美紀、西川里佳、納谷幸男、中川昌之、関直彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      (パシフィコ横浜)横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Tumour suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOKM1 in prostate cancer

    • Author(s)
      S.Kojima, H.Enomoto, H.Yoshino, T.Itesako, T.Chiyomaru, T.Kinoshita, M.Fuse, Y.Goto, R.Nishikawa, Y.Naya, M.Nakagawa, N Seki
    • Organizer
      29th Annual EAU Congress
    • Place of Presentation
      Stockholm(スウェーデン)
    • Year and Date
      2014-04-11 – 2014-04-15
    • Data Source
      KAKENHI-PROJECT-26462430
  • [Presentation] Tumor suppressive microRNA-224 inhibits cancer cell migration and invasion via targeting TPD52 in prostate cancer.

    • Author(s)
      Goto Y, Nishikawa R, Kojima S, Sakamoto S, Kawamura K, Imamoto T, Chiyomaru T, Enokida H, Kinoshita T, Naya Y, Nakagawa M, Ichikawa T, Seki N.
    • Organizer
      American Urological Association annual meeting 2014
    • Place of Presentation
      米国フロリダ州オーランド市 Orange County Convention Center
    • Year and Date
      2014-05-16 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25293333
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  • 1.  HANAZAWA Toyoyuki (90272327)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 37 results
  • 2.  Mizuno Keiko (50531414)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 4 results
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    # of Collaborated Products: 2 results
  • 4.  ENOKIDA Hideki (80347103)
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    # of Collaborated Products: 30 results
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    # of Collaborated Products: 2 results
  • 6.  NAKAGAWA Masayuki (90164144)
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    # of Collaborated Products: 29 results
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  • 62.  YAMAZAKI Masashi (50281712)
    # of Collaborated Projects: 1 results
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  • 63.  OKAWA Akihiko (30312945)
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  • 64.  SHIBA Masashi (20301096)
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  • 65.  HAYASHI Hedeki (20312960)
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  • 77.  SUZUKI Makoto (80312940)
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  • 79.  NAKAJIMA Takahiro (20400913)
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  • 80.  MATAKI Hiroko (60750750)
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    # of Collaborated Products: 2 results
  • 81.  Inoue Hiromasa (30264039)
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  • 82.  OKATO ATSUSHI (90756719)
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  • 83.  ARAI TAKAYUKI (40793055)
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  • 84.  KOSHIZUKA KEIICHI (00791609)
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  • 86.  Uchida Akifumi (40707923)
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  • 87.  星野 英久 (90507188)
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  • 88.  岡本 龍郎 (80568626)
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  • 89.  櫻井 大樹 (10375636)
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  • 90.  飯笹 俊彦 (10272303)
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  • 91.  田辺 寛 (40814306)
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  • 92.  大迫 祐作 (80791532)
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  • 93.  吉満 工平 (70836113)
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  • 94.  佐竹 霜一 (20866438)
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  • 95.  野田 昌宏 (40836128)
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  • 96.  田中 貴子 (50866415)
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  • 97.  保坂 優斗 (70866425)
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  • 98.  木下 崇 (00648462)
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  • 99.  萩原 陽子 (30992226)
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  • 100.  満枝 怜子 (80992479)
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  • 101.  中条 哲浩 (20404486)
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  • 102.  又木 雄弘 (10444902)
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  • 103.  川崎 洋太 (90770420)
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  • 104.  山崎 洋一 (80912857)
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  • 105.  馬場 研二 (30642615)
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  • 106.  鶴田 祐介 (70812767)
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  • 107.  笠松 厚志 (60375730)
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  • 108.  中嶋 大 (50431747)
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  • 109.  峯村 周 (00972457)
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  • 110.  KIJIMA Yuko
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    # of Collaborated Products: 2 results
  • 111.  KURAHARA Hiroshi
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    # of Collaborated Products: 1 results
  • 112.  滝口 正樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 113.  布施 美樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 114.  高野 晴子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 115.  美園 俊祐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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