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Chiba Natsuko  千葉 奈津子

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CHIBA Natuko  千葉 奈津子

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Researcher Number 50361192
Other IDs
Affiliation (Current) 2025: 東北大学, 加齢医学研究所, 教授
Affiliation (based on the past Project Information) *help 2014 – 2025: 東北大学, 加齢医学研究所, 教授
2007 – 2013: Tohoku University, 加齢医学研究所, 准教授
2004 – 2006: 東北大学, 加齢医学研究所, 助手
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / General surgery / Tumor biology / Tumor therapeutics / Tumor biology / Laboratory medicine
Except Principal Investigator
Basic Section 50010:Tumor biology-related / Biological Sciences / Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery
Keywords
Principal Investigator
がん / BRCA1 / 中心体 / がん関連分子 / 癌 / DNA損傷 / 細胞分裂 / 乳がん / DNA修復 / 家族性乳癌 … More / がん治療 / ゲノム不安定性 / DNA損傷応答 / ゲノム安定性維持 / ユビキチン化 / 抗がん剤感受性 / 家族性乳がん / 細胞分裂制御 / バイオマーカー / 標的分子 / 化学療法 / 乳癌 / 遺伝子診断 … More
Except Principal Investigator
BRCA1 / 中心体 / 遺伝性乳がん / がん抑制遺伝子 / MLH1 / MYH / p53 / 機能解析 / 組織特異性 / 発がん予防 / estrogen / carcinogenesis / FACS / HBOC / BRCA / 局在制御 / 翻訳後修飾 / 乳がん / 中心小体 / RACK1 / BAP1 / 癌化 / 脱ユビキチン化 / BAP1遺伝子 / 食道扁平上皮癌 / 変異 / TP53 / 腫瘍関連遺伝子 / がん関連遺伝子 / BRCA2 / 機能診断 / PTEN / missense mutation / ミスセンス変異 / 遺伝子変異 Less
  • Research Projects

    (15 results)
  • Research Products

    (184 results)
  • Co-Researchers

    (22 People)
  •  新たな中心体標的療法の開発のためのがん関連分子による中心体応答制御の統合的理解Principal Investigator

    • Principal Investigator
      千葉 奈津子
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  中心小体複製の組織特異性に基づくBRCA1関連乳がんの発がん機構の解明

    • Principal Investigator
      吉野 優樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  末梢血リンパ球でのHBOCの診断、発がん予防、予測システムの開発

    • Principal Investigator
      渡部 剛
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tohoku Medical and Pharmaceutical University
  •  Development of cancer therapy targeting genome instability by centrosome dysregulation and DNA damagePrincipal Investigator

    • Principal Investigator
      千葉 奈津子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  Tissue-specific carcinogenesis due to dysregulation of centrosome duplication by BRCA1 complex

    • Principal Investigator
      Yoshino Yuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  Development of Targeting therapy for centrosome dysregulation in cancerPrincipal Investigator

    • Principal Investigator
      Chiba Natsuko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  Elucidation of regulatory mechanism to maintain genome stability by novel BRCA1-interacting molecules and development of cancer therapyPrincipal Investigator

    • Principal Investigator
      CHIBA Natsuko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Tohoku University
  •  Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma; survey for molecular targeted medicine

    • Principal Investigator
      Mori Takahiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Elucidation of regulatory mechanism of DNA repair factor to overcome intractable breast cancerPrincipal Investigator

    • Principal Investigator
      Chiba Natsuko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Tohoku University
  •  Function of the novel tumor suppressor in cell division and carcinogenesisPrincipal Investigator

    • Principal Investigator
      Chiba Natsuko
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Tohoku University
  •  Analysis of a novel BRCA1-associated protein for new cancer therapyPrincipal Investigator

    • Principal Investigator
      CHIBA Natsuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Identifcataion of new molecular targets by analysis of multiple DNA repair activity of familial breast cancer susceptibility genePrincipal Investigator

    • Principal Investigator
      CHIBA Natsuko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Development of functional assays for tumor-related genes

    • Principal Investigator
      ISHIOKA Chikashi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  プロテオミクス解析を利用した家族性乳癌原因遺伝子BRCA1の機能診断法の開発Principal Investigator

    • Principal Investigator
      千葉 奈津子
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tohoku University
  •  がん関連遺伝子変異の検出および機能評価法の開発

    • Principal Investigator
      ISHIOKA Chikashi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] New functions of BRCA1/2 in regulating carcinogenesis and drug sensitivity. Practical Guide to Hereditary Breast and Ovarian cancer - Annual meeting of the Japanese Organization of Hereditary Breast and Ovarian Cancer2023

    • Author(s)
      Fang Zhenzhou、Yoshino Yuki、Chiba Natsuko
    • Total Pages
      17
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Book] 疾患の原因遺伝子・タンパク質の解析と診断/治療技術の開発 5章 がんの発症原因となる変異遺伝子・タンパク質とその診断・治療への活用2022

    • Author(s)
      本成登貴和, 千葉奈津子
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Book] Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice, Variants of uncertain significances in hereditary breast and ovarian cancer2021

    • Author(s)
      Yuki Yoshino and Natsuko Chiba
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Book] インフォームドコンセントのための図説シリーズ 抗悪性腫瘍薬-分子標的治療薬-改訂版2015

    • Author(s)
      吉野優樹、千葉奈津子
    • Total Pages
      120
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Book] 最新遺伝性腫瘍・家族性腫瘍研究と遺伝カウンセリング2015

    • Author(s)
      藤田拡樹、千葉奈津子
    • Total Pages
      300
    • Publisher
      メディカル ドゥ
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Book] BRCA1 is involved in the transcription-coulpled repair of UV lesions. Nano-Biomedical Engineering 20112012

    • Author(s)
      Chiba N and Wei L
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] Identification of a novel BARD1-interacting protein and an analysis of its function in the regulation of mitosis. Nano-Biomedical Engineering 20112012

    • Author(s)
      Matsuzawa A, Wei L, Kashiwagi R, Shibata S, Mochiduki H, Maseki E, Furukawa Y, Kato K, Shiono M, and Chiba N.
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] Regulation of BRCA1 and BARD1 expression levels in Response to DNA damageNano-Biomedical Engineering 20112012

    • Author(s)
      Maseki E, Shiono M, Matsuzawa A, Wei L, Kashiwagi R, Furukawa Y, Shibata S, Mochiduki H, Kato K, and Chiba N.
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] Nano-Biomedical Engineering 2011, Proceeding of the Tohoku University Global Centre of Excellence Programme, Global Nano-Biomedical Engineering Education and Research Network Centre2012

    • Author(s)
      Natsuko Chiba
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] BRCA1 responds to DNA damage induced by laser-irradiation. Nano-Biomedical Engineering 20112012

    • Author(s)
      Wei L, Kashiwagi R, Furukawa Y, Kato K, and Chiba N.
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] Analysis of BRCA1 Accumulation at DNA Double-Strand Breaks Using a Molecular Imaging technique, Nano-Biomedical Engineering 20092009

    • Author(s)
      Wei L and Chiba N
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Book] Analysis of Tumor Suppressor Gene Using Molecular Imaging for Personalized Medicine, Nano-Biomedical Engineering 20092009

    • Author(s)
      Chiba N and Wei L
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] Knockout of Brca1-interacting factor Ola1 in female mice induces tumors with estrogen suppressible centrosome amplification2024

    • Author(s)
      Yoshino Yuki、Ogoh Honami、Iichi Yudai、Sasaki Tomohiro、Yoshida Takahiro、Ichimura Shiori、Nakayama Masahiro、Xi Wu、Fujita Hiroki、Kikuchi Megumi、Fang Zhenzhou、Li Xingming、Abe Takaya、Futakuchi Mitsuru、Nakamura Yasuhiro、Watanabe Toshio、Chiba Natsuko
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

      Volume: 1870 Issue: 5 Pages: 167138-167138

    • DOI

      10.1016/j.bbadis.2024.167138

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Journal Article] The centrosome: a critical hub for cell cycle regulation2024

    • Author(s)
      Yoshino Yuki、Fang Zhenzhou、Chiba Natsuko
    • Journal Title

      Trends in Cell Biology

      Volume: - Issue: 6 Pages: 437-439

    • DOI

      10.1016/j.tcb.2024.04.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Journal Article] Protocol to detect OLA1 polyubiquitination by Aurora A in vivo and in vitro2024

    • Author(s)
      Fang Zhenzhou、Li Xingming、Yoshino Yuki、Chiba Natsuko
    • Journal Title

      STAR Protocols

      Volume: 5 Issue: 2 Pages: 103008-103008

    • DOI

      10.1016/j.xpro.2024.103008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14584, KAKENHI-PROJECT-23K24157
  • [Journal Article] 中心体のDNA損傷応答によるがん抑制. Tumor suppression by DNA damage response of centrosome2023

    • Author(s)
      千葉奈津子
    • Journal Title

      BIOClinica

      Volume: 38 Pages: 44-48

    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Journal Article] Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation2023

    • Author(s)
      Fang Zhenzhou、Li Xingming、Yoshino Yuki、Suzuki Moe、Qi Huicheng、Murooka Hinari、Katakai Riko、Shirota Matsuyuki、Mai Pham Thi Anh、Matsuzawa Ayako、Otsuka Kei、Ishioka Chikashi、Mori Takahiro、Chiba Natsuko
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 8 Pages: 112850-112850

    • DOI

      10.1016/j.celrep.2023.112850

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14584, KAKENHI-PROJECT-22K12241, KAKENHI-PROJECT-23K24157
  • [Journal Article] <scp>BRCA1</scp> transports the <scp>DNA</scp> damage signal for <scp>CDDP</scp> ‐induced centrosome amplification through the centrosomal Aurora A2022

    • Author(s)
      Qi Huicheng、Kikuchi Megumi、Yoshino Yuki、Fang Zhenzhou、Ohashi Kazune、Gotoh Takato、Ideta Ryo、Ui Ayako、Endo Shino、Otsuka Kei、Shindo Norihisa、Gonda Kohsuke、Ishioka Chikashi、Miki Yoshio、Iwabuchi Tokuro、Chiba Natsuko
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 12 Pages: 4230-4243

    • DOI

      10.1111/cas.15573

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07143, KAKENHI-PROJECT-23K24157
  • [Journal Article] Roles of RACK1 in centrosome regulation and carcinogenesis2022

    • Author(s)
      Yoshino Y and Chiba N
    • Journal Title

      Cellular Signalling

      Volume: 90 Pages: 110207-110207

    • DOI

      10.1016/j.cellsig.2021.110207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03493, KAKENHI-PROJECT-21K07143
  • [Journal Article] DNA修復機構の基礎知識2021

    • Author(s)
      遠藤栞乃, 千葉奈津子
    • Journal Title

      産婦人科の実際

      Volume: 70(5) Pages: 479-483

    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Journal Article] BRCA1/ATF1-mediated transactivation is involved in resistance to PARP inhibitors and cisplatin2021

    • Author(s)
      Endo S, Yoshino Y, Shirota M, Watanabe G, and Chiba N
    • Journal Title

      Cancer Research Communications

      Volume: 1(2) Issue: 2 Pages: 90-105

    • DOI

      10.1158/2767-9764.crc-21-0064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Journal Article] Dysregulation of the centrosome induced by BRCA1 deficiency contributes to tissue‐specific carcinogenesis2021

    • Author(s)
      Yoshino Yuki、Fang Zhenzhou、Qi Huicheng、Kobayashi Akihiro、Chiba Natsuko
    • Journal Title

      Cancer Science

      Volume: - Issue: 5 Pages: 1679-1687

    • DOI

      10.1111/cas.14859

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15233, KAKENHI-PROJECT-19H03493, KAKENHI-PROJECT-21K07143
  • [Journal Article] The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK12020

    • Author(s)
      Otsuka Kei、Yoshino Yuki、Qi Huicheng、Chiba Natsuko
    • Journal Title

      Genes

      Volume: 11 Issue: 8 Pages: 842-842

    • DOI

      10.3390/genes11080842

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18020, KAKENHI-PROJECT-19H03493, KAKENHI-PROJECT-18K15233
  • [Journal Article] RACK1 regulates centriole duplication through the activation of polo-like kinase 1 by Aurora A.2020

    • Author(s)
      Yoshino Y*, Kobayashi A*, Qi H, Endo S, Fang Z, Shindo K, Kanazawa R, Chiba N
    • Journal Title

      Journal of Cell Science

      Volume: 133 Issue: 17 Pages: 238931-238931

    • DOI

      10.1242/jcs.238931

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03493, KAKENHI-PROJECT-18K15233
  • [Journal Article] Relationship among DNA double-strand break (DSB), DSB repair, and transcription prevents genome instability and cancer.2020

    • Author(s)
      Ui A, Chiba N, and Yasui A.
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 5 Pages: 1443-1451

    • DOI

      10.1111/cas.14404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Journal Article] Interaction between transcription and DSB repair to prevent genome instability and cancer.2020

    • Author(s)
      Ui A, Chiba N, and Yasui A.
    • Journal Title

      Cancer Science

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Journal Article] RACK1 regulates centriole duplication by controlling localization of BRCA1 to the centrosome in mammary tissue-derived cells.2019

    • Author(s)
      Yoshino Y, Qi H, Kanazawa R, Sugamata M, Suzuki K, Kobayshi A, Shindo K, Matsuzawa A, Shibata S, Endo S, Miyanishi Y, Shimaoka T, Ishioka C, Kanno S, Yasui A, and Chiba N.
    • Journal Title

      Oncogene

      Volume: 印刷中 Issue: 16 Pages: 3077-3092

    • DOI

      10.1038/s41388-018-0647-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-19H03493
  • [Journal Article] BRCA1-interacting protein OLA1 requires interaction with BARD1 to regulate centrosome number.2018

    • Author(s)
      Yoshino Y, Qi H, Fujita H, Shirota M, Abe S, Komiyama Y, Shindo K, Nakayama M, Matsuzawa A, Kobayashi A, Ogoh H, Watanabe T, Ishioka C and Chiba N.
    • Journal Title

      Molecular Cancer Research

      Volume: 6(10) Issue: 10 Pages: 1499-1511

    • DOI

      10.1158/1541-7786.mcr-18-0269

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-16K07296
  • [Journal Article] Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis2018

    • Author(s)
      Gou Watanabe, Natsuko Chiba, Tadashi Nomizu, Akihiko Furuta, Kaolu Sato, Minoru Miyashita, Hiroshi Tada, Akihiko Suzuki, Noriaki Ohuchi, Takanori Ishida
    • Journal Title

      Cancer Science

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Journal Article] 1.Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis.2018

    • Author(s)
      Watanabe G, Chiba N, Nomizu T, Furuta A, Sato K, Miyashita M, Tada H, Suzuki A, Ohuchi N, Ishida T.
    • Journal Title

      Cancer Science

      Volume: in press Issue: 6 Pages: 2027-2035

    • DOI

      10.1111/cas.13595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15006, KAKENHI-PROJECT-16H04690
  • [Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras G12D -driven tumor promotion2018

    • Author(s)
      Kurosawa Koreyuki、Inoue Yui、Kakugawa Yoichiro、Yamashita Yoji、Kanazawa Kosuke、Kishimoto Kazuhiro、Nomura Miyuki、Momoi Yuki、Sato Ikuro、Chiba Natsuko、Suzuki Mai、Ogoh Honami、Yamada Hidekazu、Miura Koh、Watanabe Toshio、Tanuma Nobuhiro、Tachi Masahiro、Shima Hiroshi
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 7 Pages: 2178-2187

    • DOI

      10.1111/cas.13638

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-18K16043, KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K16358, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-18K09243, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K19620
  • [Journal Article] Efficacy and safety of gemcitabine plus docetaxel in Japanese patients with unresectable or recurrent bone and soft tissue sarcoma: Results from a single-institutional analysis.2017

    • Author(s)
      Takahashi M, Komine K, Imai H, Okada Y, Saijo K, Takahashi M, Shirota H, Ohori H, Takahashi S, Chiba N, Mori T, Shimodaira H, Ishioka C.
    • Journal Title

      PLoS One.

      Volume: 12(5) Issue: 5 Pages: e0176972-e0176972

    • DOI

      10.1371/journal.pone.0176972

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07106, KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-15K08962, KAKENHI-PROJECT-16K10488
  • [Journal Article] Regulation of centrosome cycle2016

    • Author(s)
      Hiroki Fujita, Yuki Yoshino , and Natsuko Chiba
    • Journal Title

      Molecular & Cellular Oncology

      Volume: 3 Issue: 2 Pages: e1075643-e1075643

    • DOI

      10.1080/23723556.2015.1075643

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Journal Article] ΔNp63α induces quiescence and downregulates the BRCA1 pathway in estrogen receptor-positive luminal breast cancer cell line MCF7 but not in other breast cancer cell lines.2016

    • Author(s)
      Amin R, Morita-Fujimura Y, Tawarayama H, Semba K, Chiba N, Fukumoto M, Ikawa S
    • Journal Title

      Molecular Oncology

      Volume: 10 Issue: 4 Pages: 575-593

    • DOI

      10.1016/j.molonc.2015.11.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06733, KAKENHI-PROJECT-16H04690
  • [Journal Article] OLA1 gene sequencing in patients with BRCA1/2 mutation-negative suspected hereditary breast and ovarian cancer.2016

    • Author(s)
      Takahashi M*, Chiba N*, Shimodaira H, Yoshino Y, Mori T, Sumii M, Nomizu T, Ishioka C.
    • Journal Title

      Breast Cancer

      Volume: 24(2) Issue: 2 Pages: 336-340

    • DOI

      10.1007/s12282-016-0709-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-26460958
  • [Journal Article] Regulation of centrosome cycle2016

    • Author(s)
      Hiroki Fujita , Yuki Yoshino, and Nastuko Chiba
    • Journal Title

      Molecular & Cellular Oncology

      Volume: 3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] BRCA1結合分子OLA1の中心体制御能とゲノム安定性の維持機構2015

    • Author(s)
      千葉奈津子
    • Journal Title

      生化学

      Volume: 87 Pages: 741-743

    • NAID

      40020687424

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Journal Article] Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma2015

    • Author(s)
      Mori T, Sumii M, Fujishima F, Ueno K, Emi M, Nagasaki M, Ishioka C, Chiba N
    • Journal Title

      Cancer Sci.

      Volume: 106 (9) Issue: 9 Pages: 1118-1129

    • DOI

      10.1111/cas.12722

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462010
  • [Journal Article] BRCA1結合分子OLA1の中心体制御能とゲノム安定性の維持機構2015

    • Author(s)
      千葉奈津子
    • Journal Title

      生化学

      Volume: 87 Pages: 741-743

    • NAID

      40020687424

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] The BRCA1/BARD1-interacting protein OLA1 functions in centrosome regulation.2014

    • Author(s)
      Matsuzawa A, Kanno S, Nakayama M, Mochiduki H, Wei L, Shimaoka T, Furukawa Y, Kato K, Shibata S, Yasui A, Ishioka C, Chiba N.
    • Journal Title

      Mol Cell

      Volume: 53 Issue: 1 Pages: 101-114

    • DOI

      10.1016/j.molcel.2013.10.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22131005, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-24300327, KAKENHI-PROJECT-24310037
  • [Journal Article] BRCA1とその新規結合分子OLA1による中心体制御能と乳がん発症機構2014

    • Author(s)
      千葉奈津子
    • Journal Title

      実験医学

      Volume: 32(6) Pages: 908-910

    • Data Source
      KAKENHI-PROJECT-25640086
  • [Journal Article] 家族性乳がん原因遺伝子産物BRCA1の新規結合分子OLA1の中心体制御機構2014

    • Author(s)
      松澤綾子、千葉奈津子
    • Journal Title

      細胞工学

      Volume: 33 Pages: 432-433

    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] BRCA1とその新規結合分子OLA1による中心体制御能と乳がん発症機構2014

    • Author(s)
      千葉奈津子
    • Journal Title

      実験医学

      Volume: 32(6) Pages: 908-910

    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] Analysis of BRCA1 variants in double strand break repair by homologous recombination and single strand annealing.2013

    • Author(s)
      Towler W I, Zhang J, Ransburgh D, Toland A, Ishioka C, Chiba N, and Parvin J D.
    • Journal Title

      Human Mutation

      Volume: 34 Pages: 439-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Journal Article] Analysis of BRCA1 variants in double strand break repair by homologous recombination and single strand annealing.2013

    • Author(s)
      Towler W I, Zhang J, Ransburgh D, Toland A, Ishioka C, Chiba N, and Parvin J D.
    • Journal Title

      Human Mutation

      Volume: 34 Pages: 439-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] Analysis of Tumor Suppressor BRCA1 using Molecular Imaging2012

    • Author(s)
      Natsuko Chiba
    • Journal Title

      Tohoku University Global COE Program, Global Nano-Biomedical Engineering Education and Research Network Centre, Annals of nanoBME

      Volume: Vol.5 Pages: 211-220

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] Functional differences among BRCA1 missense mutations in the control of centrosome duplication.2012

    • Author(s)
      Kais Z, Chiba N, Ishioka C, Parvin J D
    • Journal Title

      Oncogene

      Volume: 31(6) Issue: 6 Pages: 799-804

    • DOI

      10.1038/onc.2011.271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591656, KAKENHI-PROJECT-24300327
  • [Journal Article] 個別化医療のための分子イメージング技術を用いた癌関連分子の機能解析2012

    • Author(s)
      千葉奈津子
    • Journal Title

      東北大学グローバルCOEプログラム新世紀世界の成長焦点に築くナノ医工学拠点ナノ医工学年報

      Volume: Vol.5 Pages: 231-240

    • NAID

      40019250290

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] 新規乳癌関連分子の細胞分裂制御能の解析による発癌機構の解明と治療法の開発2012

    • Author(s)
      千葉奈津子
    • Journal Title

      癌と人

      Volume: 39 Pages: 48-49

    • NAID

      120004852415

    • Data Source
      KAKENHI-PROJECT-24300327
  • [Journal Article] Identifying the effect of BRCA1 mutations on homologous recombination using cells that express endogenous wild-type2011

    • Author(s)
      Parvin J D, Chiba N, and Ransburgh D
    • Journal Title

      BRCA1

      Volume: 48 Issue: 48

    • DOI

      10.3791/2468

    • URL

      http://www.jove.com/index/Details.stp?ID=2468J.Vis.Exp

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein.2011

    • Author(s)
      Wei L, Lan L, Yasui A, Tanaka K, Saijo M, Matsuzawa A, Kashiwagi R, Maseki E, Hu Y, Parvin J D, Ishioka C and Chiba N
    • Journal Title

      Cancer Science

      Volume: 102(10) Issue: 10 Pages: 1840-7

    • DOI

      10.1111/j.1349-7006.2011.02037.x

    • NAID

      10030243954

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591656, KAKENHI-PLANNED-22131009
  • [Journal Article] Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination.2010

    • Author(s)
      Ransburgh D, Chiba N, Ishioka C, Toland A, and Parvin J D
    • Journal Title

      Cancer Research

      Volume: 70(3) Pages: 988-95

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20103620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] 個別化医療のための分子イメージング技術を用いた癌抑制遺伝子の機能解析2010

    • Author(s)
      千葉奈津子
    • Journal Title

      東北大学グローバルCOEプログラム 新世紀世界の成長焦点に築くナノ医工学拠点 ナノ医工学年報

      Volume: Vol.4 Pages: 222-231

    • NAID

      40017238541

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination2010

    • Author(s)
      Ransburgh, D.J., Chiba, N., Ishioka, C., Toland, A.E., Parvin, J. D
    • Journal Title

      Cancer Res 70

      Pages: 988-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17015002
  • [Journal Article] 個別化医療のための分子イメージング技術を用いた癌抑制遺伝子の機能解析2009

    • Author(s)
      千葉奈津子
    • Journal Title

      東北大学グローバルCOEプログラム 新世紀世界の成長焦点に築くナノ医工学拠点 ナノ医工学年報 Vol.3

      Pages: 211-220

    • NAID

      40017238541

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] Analysis of Tumor Suppressor Gene Using Molecular Imaging for Personalized Medicine2009

    • Author(s)
      千葉奈津子
    • Journal Title

      Tohoku University Global COE Program, Global Nano-Biomedical Engineering Education and Research Network Centre, Annals of nanoBME Vol.3

      Pages: 209-218

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article]2009

    • Author(s)
      Natsuko Chiba
    • Journal Title

      Proceeding of the Tohoku University Global Centre of Excellence Programme, Global Nano-Biomedical Engineering Education and Research Network Centre(Imperial College Press)

      Pages: 339-349

    • Data Source
      KAKENHI-PROJECT-21591656
  • [Journal Article] Rapid Recruitment of BRCA1 to DNA Double-Strand Breaks Is Dependent on Its Association with Ku802008

    • Author(s)
      Wei, L., Lan, L., Hong, Z., Yasui, A., Ishioka, C., Chiba, N
    • Journal Title

      Mol Cell Biol 28

      Pages: 7380-93

    • Data Source
      KAKENHI-PROJECT-17015002
  • [Journal Article] Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku802008

    • Author(s)
      Wei L, Lan L, Hong Z, Yasui A, Ishioka C, and Chiba N
    • Journal Title

      Mol. Cell. Biol 28(24)

      Pages: 7380-7393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] 生殖細胞変異の遺伝子診断-家族性乳癌BRCA1,BRCA2を中心に2007

    • Author(s)
      千葉奈津子,下平秀樹,石岡千加史
    • Journal Title

      実験医学 25(17)(増刊)

    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] 家族性乳癌の原因遺伝子2007

    • Author(s)
      千葉奈津子
    • Journal Title

      日本臨床 増刊 65(6)

      Pages: 601-605

    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] 生殖細胞変異の遺伝子診断-家族性乳癌BRCA1, BRCA2を中心に2007

    • Author(s)
      千葉奈津子
    • Journal Title

      実験医学 増刊 25(17)

      Pages: 2629-2634

    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] 家族性乳癌の原因遺伝子2007

    • Author(s)
      千葉奈津子,石岡千加史
    • Journal Title

      日本臨床2007年増刊 乳癌ー基礎・臨床のアップデート 65(6)

      Pages: 601-605

    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] A dose escalation study of docetaxel and nedaplatin in patients with relapsed or refractory squamous cell carcinoma of the esophagus pretreated using cisplatin, 5-fluorouracil and radiation2006

    • Author(s)
      Yoshioka T , Sakayori M, Kato S, Chiba N, Miyazaki S, Nemoto K, Shibata H, Shimodaira H, Ohtsuka K, Kakudo Y, Sakata Y, and Ishioka C
    • Journal Title

      Int J Clin Oncol 11(6)

      Pages: 454-460

    • NAID

      10020571819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] 家族性乳癌の遺伝子検査に関わる問題点2006

    • Author(s)
      酒寄真人, 千葉奈津子, 河原正典, 白石千子, 武田元博, 野水整, 野口眞三郎, 大内憲明, 竹之下誠一, 石岡千加史
    • Journal Title

      家族性腫瘍 6(1)

      Pages: 7-11

    • NAID

      130007540991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Journal Article] BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II2005

    • Author(s)
      Starita, L.M., Horwitz, A.A., Keogh, M.C., Ishioka, C., Parvin, J.D., Chiba, N
    • Journal Title

      J Biol Chem 280

      Pages: 24498-505

    • Data Source
      KAKENHI-PROJECT-17015002
  • [Presentation] BARD1 suppresses the OLA1 polyubiquitination by Aurora A to regulate centrosome maturation.2023

    • Author(s)
      Li X, Fang Z, Murooka H, Watanabe M, Yoshino Y, Mori T, and Chiba N
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] BRCA1-associated protein RACK1 regulates centrosome duplication in breast cancer cells.2023

    • Author(s)
      Yoshino Y, Fang Z, and Chiba N
    • Organizer
      第8回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] BRCA1結合分子RACK1による中心体複製制御機構の解析2023

    • Author(s)
      吉野 優樹、方 震宙、千葉 奈津子
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] Aurora A ubiquitinates the BRCA1-interacting protein OLA1 to regulate centrosome maturation2023

    • Author(s)
      千葉 奈津子, 方 震宙, 李 星明, 吉野 優樹, 森 隆弘.
    • Organizer
      第46回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] BRCA1-interacting protein OLA1 promotes DNA damage-induced centrosome amplification through the activation of PLK1.2023

    • Author(s)
      Fang Z, Kobayashi R, Hsiao T, Yoshino Y, Qi, H and Chiba N.
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] NEK2 regulates centrosome number through promoting OLA1 ubiquitination by Aurora A.2022

    • Author(s)
      Fang Z, Li X, Yoshino Y, Ishioka C, Mori T, and Chiba N.
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] NEK2はAurora AによるOLA1のユビキチン化を促進して中心体数を制御する2022

    • Author(s)
      方 震宙、李 星明、吉野 優樹、石岡 千加史、森 隆弘、千葉 奈津子
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] BRCA1 is involved in the ubiquitination of OLA1 by Aurora A to promote centrosome maturation.2022

    • Author(s)
      Li X, Fang Z, Yoshino Y, Ishioka C, Mori T, and Chiba N.
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] BRCA1はAurora AによるOLA1のユビキチン化に作用して中心体成熟を促進する2022

    • Author(s)
      李 星明、方 震宙、吉野 優樹、石岡 千加史、森 隆弘、千葉 奈津子
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] Effects of functional changes in hereditary breast cancer gene products on carcinogenesis and drug resistance2022

    • Author(s)
      吉野 優樹, 遠藤 栞乃, 千葉 奈津子
    • Organizer
      第81回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] Maintenance of genome integrity and chemoresistance by BRCA1 tumor suppressor2022

    • Author(s)
      Natsuko Chiba
    • Organizer
      12th AACR-JCA Joint Conference, Breakthroughs in Cancer Research
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] BRCA1とその関連分子の変化による中心体制御異常とゲノム不安定性2022

    • Author(s)
      千葉 奈津子、吉野 優樹、方 震宙
    • Organizer
      第81回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] Alteration of BRCA1-asscociated proteins causes centrosome aberration resulting in genome instability2022

    • Author(s)
      千葉 奈津子
    • Organizer
      第81回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24157
  • [Presentation] Aurora A-dependent ubiquitination of OLA1 regulates centrosome number through controlling the recruitment of PCM proteins2021

    • Author(s)
      Zhenzhou Fang, Xingming Li, Moe Suzuki, Yuki Yoshino, Huicheng Qi, Takahiro Mori, and Natsuko Chiba
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] 中心体におけるBRCA1の局在部位とその制御機構の解析2021

    • Author(s)
      吉野 優樹、千葉 奈津子
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] 相同組換え修復能の評価による発がんリスクとPARP阻害剤感受性の予測2021

    • Author(s)
      千葉奈津子
    • Organizer
      順天堂大学難病の診断と治療研究センター/ゲノム診療センター 第32回難病・遺伝医学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] がんにおける相同組換え修復能とPARP阻害剤感受性2021

    • Author(s)
      千葉奈津子
    • Organizer
      第177回 愛宕産婦人科研究会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] 発がんと薬剤感受性に関与するBRCA1/2の新たな機能2021

    • Author(s)
      千葉奈津子
    • Organizer
      第1回一般社団法人日本遺伝性乳癌卵巣癌総合診療制度機構学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] Regulatory mechanism of precise localization of BRCA1 in centrosome2021

    • Author(s)
      Yuki Yoshino, Natsuko Chiba
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] Aurora AによるOLA1のユビキチン化はPCMを制御して中心体数をコントロールする2021

    • Author(s)
      方 震宙、李 星明、鈴木 萌、吉野 優樹、斉 匯成、森 隆弘、千葉 奈津子
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] BRCA1はATMによるリン酸化を介してDNA損傷シグナルを中心体に輸送する2021

    • Author(s)
      千葉 奈津子、菊池 めぐみ、方 震宙、後藤 孝太、吉野 優樹、石岡 千加史、斉 匯成
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07143
  • [Presentation] BRCA1 transports DNA-damaging signal to centrosome through its phosphorylation by ATM2021

    • Author(s)
      Natsuko Chiba, Megumi Kikuchi, Zhenzhou Fang, Takato Goto, Yuki Yoshino, Chikashi Ishioka, and Huicheng Qi
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] Dysfunction of centrosome regulation by BRCA1-containing complex increases tumor heterogeneity.2020

    • Author(s)
      Natsuko Chiba, Huicheng Qi, Yuki Yoshino.
    • Organizer
      AACR Virtual Special Conference: Tumor Heterogeneity: Form Single cell to Clinical Impact
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] DNA修復とDNA損傷応答を標的とした新規がん治療2020

    • Author(s)
      千葉奈津子
    • Organizer
      第79回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BRCA1関連乳がんの 新たな診断法の開発と 発がん機構の解析.2020

    • Author(s)
      吉野 優樹, 遠藤 栞乃, 渡部 剛, 千葉奈津子.
    • Organizer
      第8回HBOCコンソーシアム学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] リン酸化BRCA1はAurora Aの中心体局在を介してDNA損傷後の中心体増幅を制御する2020

    • Author(s)
      斉匯成、吉野優樹、菊池 めぐみ、方震宙、石岡千加史、千葉奈津子.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BRCA1のゲノム安定性維持能の破綻の発がんと抗がん剤感受性への影響について2019

    • Author(s)
      千葉奈津子
    • Organizer
      「7大学連携個別化がん医療実践者養成プラン」第54回がんプロセミナー
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] A novel BRCA1-interacting protein, RACK1, contributes centriole duplication in mammary cells via regulation of PLK1.2019

    • Author(s)
      Yoshino Y, Kobayashi A, Qi H, Endo S, Fang Z, Chiba N.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] Aurora AによるOLA1のユビキチン化は中心体複製制御に重要である2019

    • Author(s)
      方震宙, 齋匯成, 森隆弘, 吉野優樹, 鈴木萌, 石岡千加史, 千葉奈津子.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] Centrosome regulation by a novel BRCA1 complex: insight into tissue-specific carcinogenesis.2019

    • Author(s)
      Yoshino Y, Qi H, Endo S, Fang Z, Otsuka K, Chiba N.
    • Organizer
      The 14th International Symposium of the Institute Network for Biomedical Sciences
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] RCA1/2によるゲノム安定性維持機構とその機能破綻による発がん2019

    • Author(s)
      千葉奈津子
    • Organizer
      「がんプロ」特別公開講演会 がんゲノム医療先端レクチャー
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BARD1アイソフォームの発現は中心体の異常な伸長を引き起こす.2019

    • Author(s)
      大塚慧, 内山千尋, 吉野優樹, 齋匯成, 千葉奈津子.
    • Organizer
      第42回分子生物学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BRCA1はDNA損傷後のAurora Aの中心体局在を制御する.2019

    • Author(s)
      菊地めぐみ, 齋匯成, 趙懿, 方震宙, 吉野優樹, 千葉奈津子.
    • Organizer
      第37回染色体ワークショップ・第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] 新規BRCA1結合分子であるOLA1とRACK1は中心体複製を制御してゲノム安定性に寄与する2019

    • Author(s)
      千葉 奈津子, 吉野 優樹, 斉 匯成, 遠藤栞乃, 方 震宙, 石岡 千加史, 安井 明
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BRCA1とその関連分子による中心体のDNA損傷応答機構の解明.2019

    • Author(s)
      斉匯成, 菊地めぐみ, 大橋和音, 方震宙, 吉野優樹, 千葉奈津子.
    • Organizer
      第37回染色体ワークショップ・第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-19H03493
  • [Presentation] BRCA1結合分子BIP2の過剰発現はPLK1とAurora Aの活性化により中心体過剰複製を引き起こす2018

    • Author(s)
      小林輝大, 吉野優樹, 千葉奈津子
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] 新規BRCA1結合分子RACK1 の中心体複製制御能2018

    • Author(s)
      吉野優樹, 齋匯成, 小林輝大, 遠藤栞乃, 方震宙, 千葉奈津子.
    • Organizer
      第36回染色体ワークショップ 第17回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] Function of BRCA1-interacting proteins OLA1 and BIP in centrosome and carcinogenesis2018

    • Author(s)
      Yuki Yoshino, Huicheng Qi, Kei Otsuka, and Natsuko Chiba
    • Organizer
      BASSER CENTER FOR BRCA 6th Annual Scientific Symposium BRCA1, BRCA2 and Beyond: An Update on hereditary Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] 中心体制御における新規BRCA1結合因子OLA1とBARD1の相互作用の重要性2018

    • Author(s)
      吉野優樹, 齋匯成, 藤田拡樹, 小林輝大, 千葉奈津子.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1結合分子OLA1の中心体のDNA損傷応答における機能2017

    • Author(s)
      齋匯成, 方震宙, 新藤一葉, 吉野優樹, 千葉奈津子.
    • Organizer
      第34回染色体ワークショップ
    • Place of Presentation
      木更津
    • Year and Date
      2017-01-11
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1の新規結合分子Ola1のノックアウトマウスの表現型の解析.2017

    • Author(s)
      吉田貴大, 吉野優樹, 小河穂波, 佐々木伯大, 中村保宏, 渡邊利雄, 千葉奈津子.
    • Organizer
      生命科学系学会合同年次大会 ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1 supresses centrosome amplification induced by BIP2 over-expression in mammary epithelial cells.2017

    • Author(s)
      Shino Endo, Yuki Yoshino, Akihiro Kobayashi, Qi Huicheng, Natsuko Chiba.
    • Organizer
      第75回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1-interacting protein OLA1 is involved in the centrosomal duplication and response to DNA damage.2017

    • Author(s)
      Huicheng Qi, Kazune Ohashi, Fang Zhenzhou, Yuki Yoshino, Natsuko Chiba.
    • Organizer
      The 33rd International Symposium of Radiation Biology Center, Kyoto University
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] Function of the novel BRCA1-interacting protein OLA1 in centrosomal regulation and carcinogenesis.2017

    • Author(s)
      Yuki Yoshino, Huicheng Qi, Natsuko Chiba.
    • Organizer
      2nd Global Onsight Conference on Breast Cancer
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1結合分子OLA1による中心体のDNA損傷応答機構の解明2017

    • Author(s)
      齋匯成, 吉野優樹, 方震宙,千葉奈津子.
    • Organizer
      第69回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] DNA損傷後の中心体数の増加のメカニズムの解明.2017

    • Author(s)
      斉匯成, 大橋和音, 方震宙, 吉野優樹, 千葉奈津子.
    • Organizer
      第34回染色体ワークショップ 第15回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] 新規中心体制御因子RACK1によるBRCA1中心体局在制御と発がん2017

    • Author(s)
      吉野優樹, 小林輝大, 菅股眞美, 早坂美月, 齋匯成, 千葉奈津子.
    • Organizer
      第69回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1-interacting protein OLA1 regulates centrosome amplification induced by DNA damage2017

    • Author(s)
      Huicheng Qi, Yuki Yoshino, Natsuko Chiba.
    • Organizer
      生命科学系学会合同年次大会 ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] 新規BRCA1結合分子BIP2による中心体数制御機の分子機構2016

    • Author(s)
      吉野優樹、鈴木健太、菅股眞美、齋匯成、千葉奈津子
    • Organizer
      第33回染色体ワークショップ 第14回核ダイナミクス研究会
    • Place of Presentation
      松島一の坊(宮城県・松島町)
    • Year and Date
      2016-01-12
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 中心体制御因子としての新規BRCA1結合因子BIP2の同定2016

    • Author(s)
      吉野優樹, 齋匯成, 石岡千加史, 安井明, 千葉奈津子.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1依存性に中心体数を制御する新規中心体タンパク質BIP2の同定2016

    • Author(s)
      吉野優樹, 齋匯成, 菅股眞美, 安井明, 千葉奈津子.
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] 遺伝性乳がん・卵巣がんの現状と今後の展望2016

    • Author(s)
      千葉奈津子
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1の新規結合分子OLA1の中心体制御能の破綻と発がん2016

    • Author(s)
      千葉奈津子
    • Organizer
      第19回 東北家族性腫瘍研究会学術集会
    • Place of Presentation
      TKPガーデンシティ仙台(宮城県・仙台市)
    • Year and Date
      2016-01-30
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 新規中心体タンパク質BIP2はBRCA1の中心体局在と発がん機構に関与する2016

    • Author(s)
      齋匯成, 吉野優樹, 石岡千加史, 千葉奈津子.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] BRCA1結合分子OLA1の中心体制御機構の解析2016

    • Author(s)
      吉野優樹、藤田拡樹、飯地雄大、齋匯成、小宮山裕平、Linn Kullberg、佐々木勇人、千葉奈津子
    • Organizer
      第33回染色体ワークショップ 第14回核ダイナミクス研究会
    • Place of Presentation
      松島一の坊(宮城県・松島町)
    • Year and Date
      2016-01-12
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 中心体制御因子Ola1ノックアウトマウスに自然発生した造血器系腫瘍の病理組織学的解析2016

    • Author(s)
      飯地雄大、吉野優樹、中村保宏、小河穂波、二口充、藤田拡樹、渡邉利雄、千葉 奈津子
    • Organizer
      第20回 造血器腫瘍研究会
    • Place of Presentation
      かずさアカデミアホール(千葉県・木更津市)
    • Year and Date
      2016-01-23
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] BRCA1結合分子OLA1の中心体制御機構の解析2016

    • Author(s)
      吉野優樹、藤田拡樹、飯地雄大、齋匯成、小宮山裕平、Linn Kullberg、佐々木勇人、千葉奈津子
    • Organizer
      第33回染色体ワークショップ 第14回核ダイナミクス研究会
    • Place of Presentation
      松島一の坊(宮城県・松島町)
    • Year and Date
      2016-01-12
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] 新規BRCA1結合分子OLA1と協調したBARD1の中心体制御機構2016

    • Author(s)
      藤田拡樹、吉野優樹、阿部舜、小宮山裕平、佐々木勇人、齋匯成、千葉奈津子
    • Organizer
      第33回染色体ワークショップ 第14回核ダイナミクス研究会
    • Place of Presentation
      松島一の坊(宮城県・松島町)
    • Year and Date
      2016-01-12
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 新規中心体タンパク質BIP2はBRCA1の中心体局在制御に関与する2016

    • Author(s)
      新藤一葉, 吉野優樹, 齋匯成, 菅股眞美, 早坂美月, 千葉奈津子.
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16H04690
  • [Presentation] OLA1 regulates centrosome number together with BRCA1 and BARD12015

    • Author(s)
      藤田拡樹, 吉野優樹, 石岡千加史,千葉奈津子
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] BRCA1結合分子OLA1の中心体制御能の破綻による発がん機構2015

    • Author(s)
      藤田拡樹, 吉野優樹, 阿部舜, 齋匯成, 小宮山祐平, 千葉奈津子
    • Organizer
      第23回DNA複製・組み換え・修復ワークショップ
    • Place of Presentation
      焼津グランドホテル(静岡県・焼津市)
    • Year and Date
      2015-10-19
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] BRCA1結合分子OLA1の中心体制御能の破綻による発がん機構2015

    • Author(s)
      千葉奈津子
    • Organizer
      第23回DNA複製・組み換え・修復ワークショップ
    • Place of Presentation
      焼津グランドホテル(静岡県・焼津市)
    • Year and Date
      2015-10-19
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] OLA1 regulates centrosome number together with BRCA1 and BARD12015

    • Author(s)
      藤田拡樹, 吉野優樹, 石岡千加史,千葉奈津子
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] OLA1 and BRCA1/BARD1 heterodimer cooperatively regulate centrosome replication and carcinogenesis2015

    • Author(s)
      Hiroki Fujita, Yuki Yoshino, Shun Abe, Kaisei, Sai, Yuhei Komiyama, Chikashi Ishioka, and Natsuko Chiba
    • Organizer
      第38回分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] OLA1 and BRCA1/BARD1 heterodimer cooperatively regulate centrosome replication and carcinogenesis2015

    • Author(s)
      Hiroki Fujita, Yuki Yoshino, Shun Abe, Kaisei, Sai, Yuhei Komiyama, Chikashi Ishioka, and Natsuko Chiba
    • Organizer
      第38回分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma.2015

    • Author(s)
      Mori, T.,Sumii, M.,Fujishima, F.,Ueno, K.,Emi, M.,Nagasaki, M.,Ishioka, C.,Chiba, N.
    • Organizer
      AACR Annual Meeting 2015
    • Place of Presentation
      Philadelphia, USA.
    • Year and Date
      2015-04-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462010
  • [Presentation] 切除不能進行再発大腸癌に対するregorafenibとTAS102の治療効果に関す る後方視野的検討2015

    • Author(s)
      小峰啓吾,小林輝大,伊藤祝栄,大石隆之,岡田佳也,今井源,西條憲,高 橋昌宏,高橋雅信,高橋信,城田英和,千葉奈津子,下平秀樹,森隆弘,石岡千 加 史
    • Organizer
      日本癌治療学会学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-25462010
  • [Presentation] ヒト食道扁平上皮癌 でのBAP1遺伝子変異は脱ユビキチン化能を低下させ細胞内局在を変化させる2015

    • Author(s)
      森隆弘,千葉奈津子,江見充,石岡千加史,藤島史喜
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25462010
  • [Presentation] BRCA1の新規結合分子OLA1による中心体制御能とその機能破綻による発がん機構2014

    • Author(s)
      千葉奈津子
    • Organizer
      第7回Symphony
    • Place of Presentation
      東京
    • Year and Date
      2014-09-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] Analysis of Tumor Suppressor BRCA1 using Molecular Imaging2012

    • Author(s)
      Natsuko Chiba
    • Organizer
      The 18^<th> International Symposium on Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
    • Place of Presentation
      Sendai
    • Year and Date
      2012-03-06
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Analysis of Tumor Suppressor BRCA1 using Molecular Imaging.2012

    • Author(s)
      Chiba N, Furukawa Y, Shibata S, Kato K, Mochiduki H, Shiono M, Maseki E, and Matsuzawa A
    • Organizer
      The 18th International Symposium on Nano-Biomedical
    • Place of Presentation
      Engineering in the East Asian-Pacific Rim Region (Sendai, Japan)
    • Year and Date
      2012-03-06
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] A novel BARD1-interacting protein regulates centrosome and cytokinesis.2011

    • Author(s)
      Matsuzawa A, Shibata S, Mochiduki H, Maseki E, , Furukawa Y, Kato K, Shiono M, and Chiba N
    • Organizer
      5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore, Singapore
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Function of BRCA1 in DNA damage repair and centrosome regulation.2011

    • Author(s)
      Chiba N, Matsuzawa A, Kashiwagi R, Maseki E, Kanno S, Wei L, Furukawa Y, Shibata S, Ishioka C, and Yasui A
    • Organizer
      The 6th International Symposium of Institute Network
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Regulation of the level of BRCA1/BARD1 expression.2011

    • Author(s)
      Maseki E, Shiono M, Matsuzawa A, Furukawa Y, Shibata S, Mochiduki H, Kato K, and Chiba N
    • Organizer
      5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore, Singapore
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] SNPs of Aurora-A are involved in the centrosome regulation of BRCA1 and malignant potential of esophageal cancer. Aurora-Aの一塩基多型はBRCA1による中心体制御と食道癌の悪性度に関与する。2011

    • Author(s)
      Matsuzawa A, Mori T, Mochiduki H, Chiba N
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Analysis of tumor suppressor gene using Molecular imaging technique for paesonalized medicine2010

    • Author(s)
      千葉奈津子
    • Organizer
      The 12^<th> Internatopnal Symposium on Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] The effect of BRCA1 missense mutations on homology directed recombination, BRCA1の点突然変異の相同組み換えへの影響2010

    • Author(s)
      Chiba N, Matsuzawa A, Kashiwagi R, Maseki E and Ishioka C
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA1はDNA単鎖切断修復に関与する2010

    • Author(s)
      柏木梨佐、古川裕美子、宇井彩子、松澤綾子、柵木絵美子、柴田峻、石岡千加史、安井明、千葉奈津子
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Analysis of tumor suppressor gene using Molecular imaging technique for personalized medicine.2010

    • Author(s)
      Chiba N, Kashiwagi R, Maseki E, and Matsuzawa A
    • Organizer
      The 12th Internatopnal Symposium on Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Regulatory mechanism of the level of BRCA1/BARD1 expression following DNA damage.2010

    • Author(s)
      aseki E, Kanno S, Matsuzawa A, Kashiwagi R, Furukawa Y, Shibata S, Yasui A, and Chiba N
    • Organizer
      4th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore, Singapore
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Regulation of BRCA1/BARD1 expression after DNA damage.2010

    • Author(s)
      Maseki E, Kanno S, Matsuzawa A, Kashiwagi R, Wei L, Ishioka C, Yasui A, and Chiba N
    • Organizer
      6th World Congress of Biomechanics
    • Place of Presentation
      Suntec City, Singapore, Singapore
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] The effect of BRCA1 missense mutations on homology directed recombination2010

    • Author(s)
      Natsuko Chiba
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Identification of a novel BARD1-interacting protein that regulates centrosome and cytokinesis中心体と細胞質分裂を制御する新規BARD1結合分子の同定2010

    • Author(s)
      Matsuzawa A, Wei L, Kashiwagi R, Maseki E, Ishioka C, Yasui A, and Chiba N
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] A novel BARD1-interacting protein functions at cell cycle regulation.2010

    • Author(s)
      Matsuzawa A, Kanno S, Wei L, Kashiwagi R, Maseki E, Ishioka C, Yasui A, and Chiba N
    • Organizer
      6th World Congress of Biomechanics
    • Place of Presentation
      Suntec City, Singapore, Singapore
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Identification of a novel BARD1-interacting protein and analyses of its function.2010

    • Author(s)
      Matsuzawa A, Kanno S, Wei L, Kashiwagi R, Maseki E, Shibata S, Furukawa Y, Ishioka C, Yasui A, and Chiba N
    • Organizer
      4th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore, Singapore
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Regulatory mechanism of the level of BRCA1/BARD1 expression following DNA damage2010

    • Author(s)
      Maseki E, Kanno S, Matsuzawa A, Kashiwagi R, Shibata S, Furukawa Y, Wei L, Ishioka C, Yasui A, and Chiba N
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA1 polyubiquitinates CSB protein in transcription-coupled repair of UV damage2009

    • Author(s)
      千葉奈津子
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA1のDNA単鎖切断修復能における機能2009

    • Author(s)
      柏木梨佐、魏雷震、松澤綾子、柵木絵美子、石岡千加史、安井明、千葉奈津子
    • Organizer
      第20回DNA複製・組み換え・修復ワークショップ
    • Place of Presentation
      滋賀県彦根市
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA1のコケイン症候群CSB蛋白のユビキチン化と転写共役修復への影響2009

    • Author(s)
      千葉奈津子、魏雷震、田中亀代次、石岡千加史、安井明
    • Organizer
      第20回DNA複製・組み換え・修復ワークショップ
    • Place of Presentation
      滋賀県彦根市
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA 1 polyubiquitinates CSB protein in transcription-coupled repair of UV damage2009

    • Author(s)
      Chiba, N, et al
    • Organizer
      68th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Pacifico Yokohama Japan
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-17015002
  • [Presentation] Identification of a new target of cancer therapy by a proteomic study. The 10th Internatopnal Symposium on Nano-Biomedical Engineering2009

    • Author(s)
      Chiba N, Matsuzawa A, Wei L, Kashiwagi R, Maseki E, Yasui A, and Kanno S
    • Organizer
      in the East Asian-Pacific Rim Region
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-16
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] BRCA1 polyubiquitinates CSB protein in transcription-coupled repair of UV damage、転写と共役したDNA修復においてBRCA1がコケイン症候群CSB蛋白をユビキチン化する2009

    • Author(s)
      千葉奈津子, 魏雷震, 田中亀代次, 安井明, 石岡千加史
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] A novel BARD1-interacting protein functions at spindle poles and midbody to regulate mitosis and cytokinesis.2009

    • Author(s)
      松澤綾子、菅野新一郎、魏雷震、柏木梨佐、柵木絵美子、石岡千加史、安井明、千葉奈津子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21591656
  • [Presentation] Tumor suppressor BRCA1 response to DNA single-strand breaks induced by laser micro-irradiation2008

    • Author(s)
      Natsuko Chiba
    • Organizer
      Th7^<th> Internatopnal Symposium on Nano-Biomedical Engineering (ISNBME-7)
    • Place of Presentation
      Tainan, Taiwan
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Recruitment of Tumor Suppressor, BRCA1 to DNA double strands induced by lasesr micro irradiation2008

    • Author(s)
      Chiba N
    • Organizer
      5th International Symposium of 2007 Tohoku University Global COEProgram Global Nano-Biomedical Engineering Education and Research Network Centre, Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
    • Place of Presentation
      Matsushima Japan
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] 家族性乳癌原因遺伝子BRCA1の紫外線損傷への集積2008

    • Author(s)
      千葉奈津子, 魏雷震, 蘭利, 佐竹正延, 安井明, 石岡千加史
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Rapid accumulation of BRCA1 at DNAdouble-strand breaks is dependent on Ku802008

    • Author(s)
      Wei L, Lan L., Hong Z, Yasui A, Satake M, Ishioka C. and Chiba N
    • Organizer
      Ataxia-Telamgiectasia Workshop 2008
    • Place of Presentation
      Ohtsu Japan
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Tumor suppressor BRCA1 response to DNA single-strand breaks induced by laser micro-irradiation2008

    • Author(s)
      Chiba N. and Wei L
    • Organizer
      The 7th Internatopnal Symposium on Nano-Biomedical Engineering (ISNBME-7)
    • Place of Presentation
      Tainan, Taiwan
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] 家族性乳癌原因遺伝子BRCA1の紫外線損傷への集積2008

    • Author(s)
      千葉奈津子
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Domain-dependent accumulation of BRCA1 at the sites of DNA damage2007

    • Author(s)
      Chiba N., Wei L, Lan L., Hong Z, Yasui A and Ishioka C
    • Organizer
      AACR-NCI-EORTC International conference Molecular targets and Cancer Therapeutics
    • Place of Presentation
      San Francisco U.S.A
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Two cases of breast cancer responding to trastuzumab monotherapy.. Asia Pacific Medical Education Initiative2007

    • Author(s)
      Chiba, N., Yoshioka, T., Takahashi, S., Shibata, H., Kato, S., Shimodaira, H., Otsuka, K., Kakudo, Y., Takahashi, M., Yasuda, K., Sakamoto, Y., Ishioka, C
    • Organizer
      3rd Asia Pacific Workshop, Molecular targeted Therapy of Cancer
    • Place of Presentation
      Shanghai China
    • Year and Date
      2007-03-10
    • Data Source
      KAKENHI-PROJECT-17015002
  • [Presentation] Domain-dependent accumulation of BRCA1 at the sites of DNA damage2007

    • Author(s)
      Chiba, N., Ishioka, C
    • Organizer
      AACR-NCI-EORTC International conference Molecular targets and Cancer Therapeutics
    • Place of Presentation
      San Francisco・U.S. A(poster)
    • Year and Date
      2007-10-23
    • Data Source
      KAKENHI-PROJECT-17015002
  • [Presentation] 家族性乳癌原因遺伝子BRCA1のN末端のDNA二本鎖切断への集積2007

    • Author(s)
      魏雷震, 千葉奈津子, 蘭利, 佐竹正延, 安井明, 石岡千加史
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Domain-dependent accumulation of BRCA1 at the sites of DNA damage2007

    • Author(s)
      Chiba N.
    • Organizer
      AACR-NCI-EORTC International conference Molecular targets and Cancer Therapeutics
    • Place of Presentation
      San Francisco U.S.A.
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] Two cases of breast cancer responding to trastuzumab monotherapy2007

    • Author(s)
      Chiba N, Yoshioka T, Takahashi S, Shibata H, Kato S, Shimodaira H, Otsuka K, Kakudo Y, Takahashi M, Yasuda K, Sakamoto Y, and Ishioka C
    • Organizer
      Asia Pacific Medical Education Initiative, 3rd Asia Pacific Workshop, Molecular targeted Therapy of Cancer
    • Place of Presentation
      Shanghai China
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] リアルタイム分析による家族性乳癌原因遺伝子BRCA1のDNA損傷への集積2006

    • Author(s)
      魏雷震, 千葉奈津子, 蘭利, 安井明, 石岡千加史
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-28
    • Data Source
      KAKENHI-PROJECT-18689032
  • [Presentation] BRCA1の新規結合分子OLA1の機能破綻と発がん機構

    • Author(s)
      千葉奈津子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 新規BRCA1結合分子OLA1は中心体の複製機構に関与する

    • Author(s)
      藤田拡樹, 安井明, 石岡千加史, 千葉奈津子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 食道扁平上皮癌でのBAP1遺伝子変異により脱ユビキチン化酵素活性が低下する

    • Author(s)
      森隆弘, 住井真紀子, 佐藤秀則, 江見充, 石岡千加史, 千葉奈津子
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25462010
  • [Presentation] The novel BRCA1-interacting protein OLA1 functions in centrosome regulation

    • Author(s)
      Matsuzawa A, Fujita H, Wui X, Saito T, Kanno S, Yasui A, and Chiba N.
    • Organizer
      The 9th 3R Symposium
    • Place of Presentation
      御殿場
    • Year and Date
      2014-11-17 – 2014-11-21
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 家族性乳癌原因遺伝子産物BRCA1の新規関連分子の中心体制御能の解析

    • Author(s)
      松澤綾子, 柴田峻, 望月寛徳, 菅野新一郎, 古川裕美子, 加藤慧, 石岡千加史, 安井明, 千葉奈津子
    • Organizer
      第32回染色体ワークショップ 第13回核ダイナミクス研究会
    • Place of Presentation
      廿日市
    • Year and Date
      2014-12-15 – 2014-12-17
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] BRCA1の新規結合分子OLA1の中心体制御能の破綻と発がん機構

    • Author(s)
      藤田拡樹, 松澤綾子, 仲山真弘, 阿部舜, 呉㬢, 千葉奈津子
    • Organizer
      第37回分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 家族性乳がん原因分子Brca1の新規結合分子Ola1の欠損マウスにおける発がん

    • Author(s)
      千葉奈津子, 小河穂波, 藤田拡樹, 呉曦, 二口充, 渡邊利雄
    • Organizer
      第19回造血器腫瘍研究会
    • Place of Presentation
      佐賀
    • Year and Date
      2015-01-23 – 2015-01-24
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 新規BRCA1/BARD1結合分子OLA1は中心体複製機構に関与する

    • Author(s)
      千葉奈津子,菅野新一郎,藤田拡樹,安井明,石岡千加史,松澤綾子
    • Organizer
      第37回分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] BRCA1の新規結合分子OLA1の機能破綻と発がん機構

    • Author(s)
      千葉奈津子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] BRCA1とその関連分子のDNA損傷部位への集積の制御機構

    • Author(s)
      原田悠、安井明、千葉奈津子
    • Organizer
      第22回DNA複製・組換え・修復ワークショップ
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25640086
  • [Presentation] BRCA1の新規結合分子Ola1のノックアウトマウスの解析.

    • Author(s)
      仲山真弘, 小河穂波, 呉曦, 藤田拡樹, 千葉奈津子.
    • Organizer
      平成25年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      大津
    • Data Source
      KAKENHI-PROJECT-24300327
  • [Presentation] 家族性乳がん原因遺伝子BRCA1の新規結合分子の同定とその癌抑制能の解明

    • Author(s)
      千葉奈津子、安井明、石岡千加史
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300327
  • 1.  Yoshino Yuki (60755700)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 56 results
  • 2.  城田 松之 (00549462)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  渡部 剛 (70451573)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 4.  ISHIOKA Chikashi (60241577)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  SHIBATA Hiroyuki (50260071)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  KATO Shunsuke (40312657)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  KANNO Shin-ichiro (10400417)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 8.  WATABANE Toshio (60201208)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SHIMODAIRA Hideki (70373214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  Sugimoto Asako (80281715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Mori Takahiro (00323030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  酒寄 真人 (20344666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  大塚 慧 (20772437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  高井 淳 (90813890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  方 震宙 (40963806)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 16.  MIYASHITA Minoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  渡辺 利雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 18.  安井 明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  俵山 寛司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  城田 英和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  佐藤 郁郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  島 礼
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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