Uemura Takeshi 植村武史

… Alternative Names

UEMURA Takeshi 植村武史

植村武史ウエムラタケシ

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Researcher Number	50401005
Other IDs
Affiliation (Current)	2025: 城西大学, 薬学部, 准教授 2025: 京都府立医科大学, 医学(系)研究科(研究院), 客員講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 城西大学, 薬学部, 准教授 2012 – 2013: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2007: Chiba University, 大学院・薬学研究院, 助教 2006: 千葉大学, 大学院薬学研究院, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Legal medicine / Functional biochemistry Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 51030:Pathophysiologic neuroscience-related / Biological pharmacy
Keywords	Principal Investigator ポリアミン / スペルミン酸化酵素 / 細胞老化 / MDL72527 / スペルミン / アミノ酸 / 老化 / バイオマーカー / エタノール / アセトアルデヒド … More / アルコール / 肝臓 / アクロレイン / リン酸化 / ジャンピング / シャンティング / リボソーム / COX4 / 翻訳 / 出芽酵母 / 輸送 … More Except Principal Investigator ポリアミン / 酸化ストレス / スペルミジンオキシだーぜ / Nrf1 / 不良タンパク質蓄積 / リボソーム衝突 / リポソームコリジョン / アクロレイン / 老化 / 筋強直性ジストロフィー / 無細胞翻訳系 / リピート病 / RAN翻訳 / バイオテクノロジー / 脳・神経 / 生理活性 / 生体分子 / 核酸 Less

ポリアミン代謝の変化に基づく新規老化マーカーと抗老化物質の創出Principal Investigator
- Principal Investigator
  
  植村武史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Josai University
ポリアミンが誘導するリピート病の発症機構とその制御による病態抑制効果の解明
- Principal Investigator
  
  小黒明広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Jikei University School of Medicine
加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出Principal Investigator
- Principal Investigator
  
  植村武史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Josai University
Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway
- Principal Investigator
  
  辻田忠志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Saga University
Development of the novel biomarker for tissue damage using polyamines and their metabolitesPrincipal Investigator
- Principal Investigator
  
  UEMURA Takeshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Legal medicine
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of function of polyamines and regulation of their contents in cells
- Principal Investigator
  
  IGARASHI Kazuei
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
酵母の細胞増殖、機能に果たすポリアミンの生理的役割Principal Investigator
- Principal Investigator
  
  植村武史
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Chiba University

All 2024 2023 2022 2013 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Inhibition of Polyamine Catabolism Reduces Cellular Senescence2023
- Author(s)
  Uemura Takeshi、Matsunaga Miki、Yokota Yuka、Takao Koichi、Furuchi Takemitsu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 17 Pages: 13397-13397
- DOI
  10.3390/ijms241713397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11860
[Journal Article] Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level.2013
- Author(s)
  Uemura, T. et al.
- Journal Title
  
  Toxicology
  
  Volume: 310 Pages: 1-7
- DOI
  10.1016/j.tox.2013.05.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-24590046, KAKENHI-PROJECT-24890195, KAKENHI-PROJECT-25870126
[Journal Article] Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level2013
- Author(s)
  Uemura T., Tanaka Y., Higashi K., Miyamori D., Takasaka T., Nagano T., Toida T., Yoshimoto K., Igarashi K., and Ikegaya H
- Journal Title
  
  Toxicology
  
  Volume: 310C Pages: 1-7
- Data Source
  KAKENHI-PROJECT-24890195
[Journal Article] Polyamine modulon in yeast-stimulation of COX4 synthesis by spermidine at the level of translation.2009
- Author(s)
  Uemura, T., et al.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2538-2545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Polyamine-modulon in yeast―stimulation of COX4 synthesis by spermidine at the level of translation2009
- Author(s)
  Uemura, T., Higashi, K., Takigawa, M., Toida, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  Int.J.Biochem.Cell Biol. 41
  
  Pages: 2538-2545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli2008
- Author(s)
  Higashi, K., Ishigure, H., Demizu, R., Uemura, T., Nishino, K., Yamaguchi, A., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Bacteriol. 190
  
  Pages: 872-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Polyamine Uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007
- Author(s)
  Takeshi Uemura, Keiko Kashiwagi, Kazuei Igarashi
- Journal Title
  
  The Journal of Biological Chemistry 282(10)
  
  Pages: 7733-7741
- Data Source
  KAKENHI-PROJECT-18770105
[Journal Article] Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007
- Author(s)
  Uemura, T., Kashiwagi, K., Igarashi, K.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 7733-7741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007
- Author(s)
  Uemura, T., et. al.
- Journal Title
  
  J. Biol.Chem 282
  
  Pages: 7733-7741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390016
[Journal Article] Identification of the Cadaverine Recognition Site on the Cadaverine-lysine Antiporter CadB2006
- Author(s)
  Waraporn Soksawatmaekhin, Takeshi Uemura, Natsuko Fukiwake, Keiko Kashiwagi, Kazuei Igarashi
- Journal Title
  
  The Journal of Biological Chemistry 281(39)
  
  Pages: 29213-29220
- Data Source
  KAKENHI-PROJECT-18770105
[Presentation] 酸化ストレスによる皮膚ダメージにおけるポリアミンの役割2024
- Author(s)
  折井瑠海, 植村武史, 古地壯光
- Organizer
  日本ポリアミン学会　第14回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミン代謝酵素阻害剤は細胞の老化を抑制する2023
- Author(s)
  松永美紀，植村武史，横田優香，高野友輔，高尾浩一，古地壯光
- Organizer
  日本ポリアミン学会第13回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミンによるRAN翻訳の誘導効果の解析2023
- Author(s)
  小黒明広, 植村武史, 町田幸大, 田島彩沙, 河合剛太, 今高寛晃
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07357
[Presentation] ホリアミン代謝が細胞老化に与える影響2023
- Author(s)
  松永美紀、横田優香、高尾浩一、植村武史、古地壯光
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] スペルミン酸化酵素SMOXの阻害による細胞老化抑制の可能性2023
- Author(s)
  植村武史、松永美紀、横田優香、折井瑠海、高尾浩一、古地壯光
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] ポリアミン代謝酵素阻害剤は細胞の老化を抑制する2023
- Author(s)
  松永美紀、横田優香、高尾浩一、植村武史、古地壯光
- Organizer
  日本ポリアミン学会　第13回年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] 転写因子Nrf1によるポリアミン代謝制御とアクロレイン産生2023
- Author(s)
  平川智章, 谷内めぐみ,吉竹紀子, 末次祐大, 井口瑶子, 植村武史, 辻田忠志.
- Organizer
  日本ポリアミン学会第13回年会
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] NF-E2-related factor 1 suppresses the expression of a spermine oxidase and the production of highly reactive acrolein2023
- Author(s)
  Tomoaki HIRAKAWA, Megumi TANIUCHI, Yoko IGUCHI, Kiko YOSHITAKE, Yudai SUETSUGU, Takeshi UEMURA, Tadayuki TSUJITA
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] Transcription factor Nrf1 can control polyamine metabolic pathway and acrolein production2023
- Author(s)
  Tomoaki HIRAKAWA, Megumi TANIUCHI, Yoko IGUCHI, Kiko YOSHITAKE, Takeshi UEMURA, Tadayuki TSUJITA
- Organizer
  Gordon Research Conference "Polyamines in Cancer, Medical Genetics, Aging, Pathogens and Plants"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] ポリアミン代謝が細胞老化に与える影響2023
- Author(s)
  松永美紀，横田優香，高野友輔，高尾浩一，古地壯光，植村武史
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] Aging associated change in polyamine metabolism2022
- Author(s)
  Takeshi Uemura, Yuka Yokota, Miki Matsunaga, Yoshihisa Akasaka, Koichi Takao, Hiroshi Ikegaya, Takemitsu Furuchi
- Organizer
  Sixth International Conference on Polyamines: Biochemical, Physiological and Clinical Perspectives
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11860
[Presentation] 新規Nrf1標的遺伝子Smoxとアクロレイン産生機序の解明2022
- Author(s)
  平川智章, 谷内めぐみ, 井口瑶子, 吉竹紀子, 植村武史, 辻田忠志
- Organizer
  第44回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] Acetaldehyde-induced ccytoxicity involves induction of spermine oxidase at the transcrptional level2013
- Author(s)
  Uemura T*, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K, and Ikegaya H
- Organizer
  Gordon Research Conference on Polyamines 2013
- Place of Presentation
  New Hampshire, USA
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] アセトアルデヒドは、スペルミンオキシダーゼを転写レベルで誘導する2013
- Author(s)
  植村　武史
- Organizer
  日本ポリアミン学会第4回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] Regulation of cellular polyamines by transport, protein sorting and metabolism2013
- Author(s)
  Uemura T, Stringer DE, Blohm-Mangone KA, Ikegaya H, Gerner EW
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] アセトアルデヒドの肝細胞毒性には，スペルミンオキシダーゼが関与する2013
- Author(s)
  植村武史，高坂友和，宮森大輔，吉本寛司，池谷　博
- Organizer
  第97次日本法医学会学術全国集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] Acetaldehyde-induced cytoxicity involves induction of spermine oxidase at the transcrptional level2013
- Author(s)
  Uemura T, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K, and Ikegaya H
- Organizer
  Gordon Research Conference on Polyamines 2013
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] Identification and function of amino acid residues on PotB and PotC involved in spermidine uptake activity.2009
- Author(s)
  Higashi, K., Sakamaki, Y., Uemura, T., Herai, E., Demizu, R., Zenda, R., Toida, T., Kashiwagi, K., Igarashi, K.
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌スペルミジン優先取り込み系の膜貫通蛋白質PodB及びPotCの性質2008
- Author(s)
  出水梨沙,東恭平,酒巻善春,植村武史,戸来江美子,善田理沙,西村和彦,柏木敬子,五十嵐一衛,木敬子,五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] 大腸菌スペルミジン優先取り込み系の膜貫通蛋白質 PotB及び PotCの性質2008
- Author(s)
  出水梨沙, 東恭平, 酒巻善春, 植村武史, 戸来江美子, 善田理沙, 西村和洋, 柏木敬子, 五十嵐一衛
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390016
[Presentation] Identificatin and characterization of polyamine uptake proteins in Saccharomyces cerevisiae2007
- Author(s)
  Takeshi Uemura, Keiko Kashiwagi, Kazuei Igarashi
- Organizer
  Gordon Research Conference on Polyamines
- Place of Presentation
  Waterville valley, NH
- Year and Date
  2007-06-16
- Data Source
  KAKENHI-PROJECT-18770105
[Presentation] アセトアルデヒドは,スペルミンオキシダーゼを転写レベルで誘導する
- Author(s)
  植村武史,東恭平,戸井田敏彦,五十嵐一衛,池谷博
- Organizer
  日本ポリアミン学会第4回年会
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] アセトアルデヒドの肝細胞毒性には,スペルミンオキシダーゼが関与する
- Author(s)
  植村武史,高坂友和,宮森大輔,吉本寛司,池谷博
- Organizer
  第97次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-24890195
[Presentation] Regulation of cellular polyamine levels by transport, protein sorting and metabolism
- Author(s)
  Uemura T., Stringer D.E., Blohm-Mangone K., Gerner E.W
- Organizer
  第86回日本生化学大会
- Data Source
  KAKENHI-PROJECT-24890195

1. 小黒明広 (00292508)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. IGARASHI Kazuei (60089597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. NISHIMURA Kazuhiro (60302569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KASHIWAGI Keiko (80169424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 今高寛晃 (50201942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 古地壯光 (00302167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 高尾浩一 (70337484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 辻田忠志 (20622046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 伊東健 (10323289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Uemura Takeshi 植村 武史

UEMURA Takeshi 植村 武史

植村 武史 ウエムラ タケシ

Research Projects

Research Products

Co-Researchers

ポリアミン代謝の変化に基づく新規老化マーカーと抗老化物質の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ポリアミンが誘導するリピート病の発症機構とその制御による病態抑制効果の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the novel biomarker for tissue damage using polyamines and their metabolitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of function of polyamines and regulation of their contents in cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

酵母の細胞増殖、機能に果たすポリアミンの生理的役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibition of Polyamine Catabolism Reduces Cellular Senescence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level2013

Author(s)

Journal Title

Data Source

[Journal Article] Polyamine modulon in yeast-stimulation of COX4 synthesis by spermidine at the level of translation.2009

Author(s)

Journal Title

Data Source

[Journal Article] Polyamine-modulon in yeast―stimulation of COX4 synthesis by spermidine at the level of translation2009

Author(s)

Journal Title

Data Source

[Journal Article] Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli2008

Author(s)

Journal Title

Data Source

[Journal Article] Polyamine Uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007

Author(s)

Journal Title

Data Source

[Journal Article] Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae2007

Author(s)

Uemura Takeshi 植村武史

UEMURA Takeshi 植村武史

植村武史ウエムラタケシ