Kim Minsoo ＫｉｍＭｉｎｓｏｏ

… Alternative Names

KIM Minsoo KIM Minsoo

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Researcher Number	50466835
Other IDs	https://orcid.org/0000-0001-8536-8653
Affiliation (Current)	2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都大学, 医学研究科, 准教授 2020: 京都大学, 医学研究科, 特定准教授 2015 – 2019: 京都大学, 白眉センター, 特定准教授 2012 – 2014: 東京大学, 医科学研究所, 特任准教授 2011: 東京大学, 医科学研究所, 特任助教 2008 – 2009: The University of Tokyo, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Bacteriology (including Mycology) / Bacteriology (including Mycology) / Basic Section 37030:Chemical biology-related / Experimental pathology Except Principal Investigator Structural biochemistry / Basic Section 56010:Neurosurgery-related / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator 病原細菌 / エフェクター / 感染制御 / ユビキチン / 抗菌剤 / ケミカルバイオロジー / 細菌感染 / 感染症 / 病原細菌感染 / 炎症 … More / 赤痢菌 / 細胞運動 / 免疫 / 蛋白質分解 / 蛋白質 / X-線構造 / エフェクタ- / 阻害剤 / 病原性大腸菌 / 細胞周期 / 感染免疫 … More Except Principal Investigator 蛋白質 / エフェクター / 細菌 / X線結晶構造解析 / 赤痢菌 / 細胞内シグナル / 血管閉塞 / 血管閉塞性疾患 / RNF213 / シグナル伝達 / もやもや病 / ユビキチン / 構造解析 / Ｘ線結晶構造解析 / IpaH / ユビキチンリガーゼ / ユビキチン修飾経路 / OspI / 複合体構造 / エフェクタータンパク質 / ユビキチン経路 Less

International collaboration for the development of new molecular-targeted antimicrobial agentsPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University
Development of anti-inflammatory drugPrincipal Investigator
- Principal Investigator
  
  KIM MINSOO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University
New antibiotics developmentPrincipal Investigator
- Principal Investigator
  
  KIM MINSOO
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto University
Structural studies of infection mechanisms targeting the NF-kB pathway by pathogenic bacterial effectors
- Principal Investigator
  
  Mizushima Tsunehiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  University of Hyogo
Functional analysis of heritable risk factors for moyamoya disease and stroke
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Bacteria Hijack host ubiquitin systemPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
バクテリアが持つユビキチン修飾システムPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infection
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
バクテリアが利用するユビキチンシステムPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
細菌病原因子と宿主標的蛋白質の相互作用基盤Principal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
病原細菌感染における宿主細胞の免疫応答解明Principal Investigator
- Principal Investigator
  
  芦田浩, KIM Minsoo, 金玟秀
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Structural analyses of bacterial effectors and their mechanisms of infection
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
Development of new therapeutic tools against pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Analysis of host cell cycle arrest mechanism by EPEC infectionPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo

[Book] Cbl proteins2008
- Author(s)
  Tezuka T, Kim M, Yamamoto T
- Publisher
  NOVA publishers
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Structural insight into the recognition of the linear ubiquitin assembly complex by <i>Shigella</i> E3 ligase IpaH1.4/2.52023
- Author(s)
  Hiragi Keito、Nishide Akira、Takagi Kenji、Iwai Kazuhiro、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 4 Pages: 317-326
- DOI
  10.1093/jb/mvac109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20H03198, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499
[Journal Article] Active site structure of the <i>Shigella flexneri</i> effector OspI2022
- Author(s)
  Nishide Akira、Takagi Kenji、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.02.15.480433
- Open Access
- Data Source
  KAKENHI-PROJECT-18K14637, KAKENHI-PROJECT-20H03198
[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-20H03790
[Journal Article] Hijacking of the host ubiquitin system by pathogenic bacteria2020
- Author(s)
  西出旭、KIM MINSOO
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 75-83
- DOI
  10.14952/SEIKAGAKU.2020.920075
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K15750, KAKENHI-PROJECT-17K08786
[Journal Article] Microglia-triggered plasticity of intrinsic excitability modulates psychomotor behaviors in acute cerebellar inflammation2019
- Author(s)
  Yamamoto M, Kim M, Imai H, Itakura Y, Ohtsuki G
- Journal Title
  
  Cell Rep
  
  Volume: 28 Issue: 11 Pages: 2923-2938
- DOI
  10.1016/j.celrep.2019.07.078
- NAID
  120006719354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08786
[Journal Article] Manipulation of host ubiquitin-proteasome system by bacterial pathogens2017
- Author(s)
  Kim Minsoo
- Journal Title
  
  Journal of The Society of Japanese Women Scientists
  
  Volume: 17 Issue: 1 Pages: 8-18
- DOI
  10.5939/sjws.17002
- NAID
  130005465162
- ISSN
  1349-4449, 2186-3776
- Language
  Japanese
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Journal Article] バクテリアの病原性とユビキチン関連修飾システム2016
- Author(s)
  M KIM
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 (8) Pages: 880-884
- Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Journal Article] Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.82016
- Author(s)
  K Takagi, et al
- Journal Title
  
  Acta Cryst
  
  Volume: F72 Issue: 4 Pages: 269-275
- DOI
  10.1107/s2053230x16002715
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01174, KAKENHI-PROJECT-15H04341, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-16K14700
[Journal Article] Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition2014
- Author(s)
  Kim M et. al
- Journal Title
  
  Cells
  
  Volume: 3 Issue: 3 Pages: 848-864
- DOI
  10.3390/cells3030848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-14J10879, KAKENHI-PROJECT-23000012, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013
- Author(s)
  Kobayashi T, et. al
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 5 Pages: 570-583
- DOI
  10.1016/j.chom.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigella flexneri effector OspI.2013
- Author(s)
  Nishide A, Kim M, Takagi K, Himeno A, Sanada T, Sasakawa C, Mizushima T.
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370049
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigell a flexneri effector OspI2013
- Author(s)
  Nishide A, et. al
- Journal Title
  
  J Mol Bio.
  
  Volume: 425 Issue: 15 Pages: 2623-2631
- DOI
  10.1016/j.jmb.2013.02.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23689027, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] 病原性バクテリアによるユビキチン修飾系の制御2012
- Author(s)
  Kim Minsoo
- Journal Title
  
  医学のあゆみ
  
  Volume: 243 Pages: 535-540
- Data Source
  KAKENHI-PROJECT-23689027
[Journal Article] p130Cas-dependent actin remodeling regulates myogenic differentiation2012
- Author(s)
  Kawauchi K, Tan WW, Araki K, Bakar F, Kim M, Fujita H, Hirata H, Sawada Y
- Journal Title
  
  Biochemical Journal
  
  Volume: 445(3) Issue: 3 Pages: 323-332
- DOI
  10.1042/bj20112169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-24570191
[Journal Article] Shigella targets epithelial tricellular junctions to spread between cells via a noncanonical clathrin-dependent endocytic pathway.2012
- Author(s)
  Makoto Fukumatsu
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 11 Issue: 4 Pages: 325-336
- DOI
  10.1016/j.chom.2012.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22390013, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23657084, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-24117507, KAKENHI-PUBLICLY-24121708
[Journal Article] Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c.2012
- Author(s)
  Takesita K
- Journal Title
  
  J. Biochem.
  
  Volume: 152 Issue: 5 Pages: 487-495
- DOI
  10.1093/jb/mvs085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227003, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-22370041, KAKENHI-PROJECT-23249013, KAKENHI-PROJECT-23689027, KAKENHI-PLANNED-22121006, KAKENHI-PUBLICLY-23121506, KAKENHI-PUBLICLY-24121705
[Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response2012
- Author(s)
  Sanada, T.
- Journal Title
  
  Nature
  
  Volume: 483 Issue: 7391 Pages: 623-626
- DOI
  10.1038/nature10894
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117002, KAKENHI-PROJECT-22790403, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23770203, KAKENHI-PROJECT-23790471
[Journal Article] Monoubiquitination of Tob/BTG family proteins competes with degradation-targeting polyubiquitination.2011
- Author(s)
  Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 409 Issue: 1 Pages: 70-4
- DOI
  10.1016/j.bbrc.2011.04.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21360398, KAKENHI-PUBLICLY-23121506, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-23689027
[Journal Article] Bacteria and host interactions in the gut epithelial barrier2011
- Author(s)
  Ashida H., Sasakawa C., et al.
- Journal Title
  
  Nat Chem Biol
  
  Volume: 8 Issue: 1 Pages: 36-45
- DOI
  10.1038/nchembio.741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471
[Journal Article] Cell death and infection : a double-edged sword for host and pathogen survival2011
- Author(s)
  Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, Sasakawa C
- Journal Title
  
  J Cell Biol
  
  Volume: 195 Issue: 6 Pages: 931-942
- DOI
  10.1083/jcb.201108081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23659220, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471
[Journal Article] Coronin7 forms a novel E2 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob2011
- Author(s)
  Watanabe M, Suzuki T, Kim M, Abe Y, Yoshida Y, Sugano S, Yamamoto T
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689027
[Journal Article] Bacterial hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment2009
- Author(s)
  Kim M, Ogawa M, Fujita Y, Yoshikawa Y, Nagai T, Koyama T, Nagai S, Lange A, Fassler R, Sasakawa C
- Journal Title
  
  Nature 459
  
  Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Bacterial hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment2009
- Author(s)
  Kim, et al.
- Journal Title
  
  Nature 459
  
  Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition2009
- Author(s)
  Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, Kim Minsoo, Mimuro H, Nakagawa I, Yanagawa T, Ishii T, Kakizuka A, Sztul E, Chakraborty T, Sasakawa C
- Journal Title
  
  Nature Cell biology 11(19)
  
  Pages: 1233-1240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] A new ubiquitin ligase involved in p57^<KIP2> proteolysis regulates osteoblast cell differentiation2008
- Author(s)
  Minsoo Kim et.al.
- Journal Title
  
  EMBO reports 9
  
  Pages: 878-884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation2008
- Author(s)
  Kim M, Nakamoto T, Nishimori S, Tanaka K, Chiba T
- Journal Title
  
  EMBO reports 9
  
  Pages: 878-884
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] 病原細菌NEL型ユビキチンリガーゼの反応中間体構造解析2023
- Author(s)
  中村真唯子，平木慶人，小杉将吾，Kim Minsoo，水島恒裕
- Organizer
  令和5年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 病原細菌NEL型ユビキチンリガーゼの反応中間体構造解析2023
- Author(s)
  中村真唯子，平木慶人，小杉将吾，Kim Minsoo，水島恒裕
- Organizer
  第9回バイオダイナミクス研究科
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Legionella菌Cif様タンパク質のX線結晶構造解析2023
- Author(s)
  馬場拓海，平木慶人，粕谷航平，小倉実，西出旭， Kim Minso，水島恒裕
- Organizer
  令和5年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Legionella菌Cif様タンパク質のX線結晶構造解析2023
- Author(s)
  馬場拓海，平木慶人，粕谷航平，小倉実，西出旭， Kim Minso，水島恒裕
- Organizer
  第9回バイオダイナミクス研究科
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] X線結晶構造解析による赤痢菌エフェクターIpaH1.4/2.5のLUBAC阻害機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  令和4年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5基質認識ドメインの構造及び基質認識機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  第5回　バイオダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5のX線結晶構造解析および機能解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第67回　日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクター IpaH1.4/2.5 による直鎖状ポリユビキチン鎖生成酵素 (LUBAC) 認識機構の解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第21回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5によるLUBAC複合体認識機構の解明2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第4回ピコバイオロジー研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Ｘ線結晶構造解析による赤痢菌エフェクターIpaH1.4及び2.5の基質認識機構の解析2020
- Author(s)
  平木慶人、西出旭、高木賢治、Kim Minsoo、水島恒裕
- Organizer
  日本結晶会　令和2年度年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Post-translational modification of Ubc13 during bacterial infection2019
- Author(s)
  Takagi K, Nishide A, Inoue J, Iwai K, Mizushima T, Kim Minsoo
- Organizer
  EMBO workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの相互作用基盤解析2019
- Author(s)
  高木賢治、西出旭、水島恒裕、Kim Minsoo
- Organizer
  第14回日本ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチンの翻訳後修飾解析2018
- Author(s)
  佐藤里紗、西出旭、永井明日香、Kim Minsoo
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] Regulation of host homeostasis by pathogenic bacterial ubiquitin ligases2018
- Author(s)
  Kim Minsoo
- Organizer
  JCUP-Ⅸ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの相互作用基盤解析2018
- Author(s)
  Kim Minsoo、高木賢治、水島恒裕
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] 脱アミド化型ユビキチンの構造解析2018
- Author(s)
  西出旭、水島恒裕、Kim Minsoo
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの認識機構解明2017
- Author(s)
  Kim Minsoo
- Organizer
  日本女性科学者の会第11回学術大会
- Place of Presentation
  大阪科学技術センター
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2016
- Author(s)
  西出旭， Kim Minsoo, 高木賢治, 古田徹郎, 笹川千尋, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspIによるTRAF6阻害機構の構造生物学解析2016
- Author(s)
  高木賢治, 西出旭, Kim Minsoo, 笹川千尋, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 構造学的手法を用いた赤痢菌エフェクター IpaH ファミリーの反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 桑原直之, 加藤龍一, 笹川千尋, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] リアルタイムでユビキチン化を測定する方法の開発2016
- Author(s)
  Kim Minsoo
- Organizer
  第39　回　日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2016
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR.2016
- Author(s)
  Takagi, K., Kim, M., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクター IpaH1880 反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2016
- Author(s)
  高木賢治, 大津彩織, Kim Minsoo, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2015
- Author(s)
  西出旭，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Regulating host immune responses with bacterial effectors2015
- Author(s)
  Minsoo Kim
- Organizer
  3rd International Picobiology Institute Symposium
- Place of Presentation
  兵庫県立大学
- Year and Date
  2015-12-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] 赤痢菌エフェクタータンパク質IpaH9.8によるNEMOの認識機構の解析2015
- Author(s)
  大津彩織，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析2015
- Author(s)
  高木賢治、Kim Minsoo、水島恒裕
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール(徳島・徳島市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural analysis of the recognition mechanism of NEMO by shigella effector IpaH9.82015
- Author(s)
  Otsu, S., Takagi, K., Kim, M., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR2015
- Author(s)
  Takagi, K., Kim, M.., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2015
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim M et.al
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim minsoo
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim minsoo
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul,Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] Real-time, lable-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase2013
- Author(s)
  金玟秀
- Organizer
  The 35^<th> Naito conference
- Place of Presentation
  札幌、日本
- Year and Date
  2013-07-10
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] OspI-Ubc13複合体構造解析による赤痢菌エフェクタータンパク質のE2酵素認識機構2013
- Author(s)
  西出旭、Minsoo Kim、高木賢治、真田貴人、笹川千尋、水島恒裕
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館 (鳥取)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 脱アミド化Ubc13の構造解析による赤痢菌感染機構の考察2013
- Author(s)
  高木賢治　西出旭、Kim Minsoo、笹川千尋、水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI2013
- Author(s)
  Nishide A., Kim M., Takagi K., Himeno A., Sanada T., Sasakawa C., Mizushima T.
- Organizer
  The 35th Naito Conference
- Place of Presentation
  ｼｬﾄﾚｰｾﾞｶﾞﾄｰｷﾝｸﾞﾀﾞﾑ(北海道)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクタータンパク質OspI-Ubc13複合体結晶構造解析による機能解析2013
- Author(s)
  西出旭,Minsoo Kim,高木賢治,真田真人,笹川千尋,水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクタータンパク質OspI 活性中心の構造解析2012
- Author(s)
  西出旭、高木賢治、Minsoo Kim、真田貴人、笹川千尋、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 病原細菌感染における宿主翻訳後修飾2012
- Author(s)
  金玟秀
- Organizer
  日本生化学学会大会
- Place of Presentation
  福岡、日本
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Regulation of host cell-cycle progression by bacterial pathogens2011
- Author(s)
  Kim Minsoo
- Organizer
  Ubiquitin Drug Discovery & diagnostics 2011
- Place of Presentation
  Philadelphia, U.S.A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Regulation of host cell-cycle progression by bacterial pathogens2011
- Author(s)
  金玟秀
- Organizer
  Uiquitin Drug Discovery & diagnostics 2011
- Place of Presentation
  Philadelphia,米国
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] 細菌エフェクターOspEとインテグリンリンクドキナーゼの結合による感染細胞の剥離抑制機構2009
- Author(s)
  金〓秀
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] 赤痢菌のエフェクターによる腸管上皮細胞のターンオーバー抑制2008
- Author(s)
  金〓秀
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] 病原細菌感染における宿主翻訳後修飾
- Author(s)
  Kim Minsoo
- Organizer
  日本生化学学会大会
- Place of Presentation
  福岡・日本
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PROJECT-24370049

1. MIZUSHIMA TSUNEHIRO (90362269)

# of Collaborated Projects: 5 results

# of Collaborated Products: 31 results
2. LEE JIHYE

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Tezuka Tohru (50312319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山吉麻子 (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Raudzus Fabian (10906358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 林剛介 (40648268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 西出旭 (80807652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷一寿 (20541204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. S Youssefian (00210576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 芦田浩 (10535115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 金玟秀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOBAYASHI Hatasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 高木賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 笹川千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岩井一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 小川道永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 三室仁美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kim Minsoo Ｋｉｍ Ｍｉｎｓｏｏ

KIM Minsoo KIM Minsoo

Research Projects

Research Products

Co-Researchers

International collaboration for the development of new molecular-targeted antimicrobial agentsPrincipal Investigator

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Development of anti-inflammatory drugPrincipal Investigator

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New antibiotics developmentPrincipal Investigator

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Structural studies of infection mechanisms targeting the NF-kB pathway by pathogenic bacterial effectors

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Functional analysis of heritable risk factors for moyamoya disease and stroke

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Bacteria Hijack host ubiquitin systemPrincipal Investigator

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バクテリアが持つユビキチン修飾システムPrincipal Investigator

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Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infection

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バクテリアが利用するユビキチンシステムPrincipal Investigator

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細菌病原因子と宿主標的蛋白質の相互作用基盤Principal Investigator

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病原細菌感染における宿主細胞の免疫応答解明Principal Investigator

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Structural analyses of bacterial effectors and their mechanisms of infection

Principal Investigator

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Development of new therapeutic tools against pathogenic bacteriaPrincipal Investigator

Principal Investigator

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Kim Minsoo ＫｉｍＭｉｎｓｏｏ