Ukawa Masami 鵜川真実

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UKAWA Masami 鵜川真実

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Researcher Number	50735511
Other IDs	https://orcid.org/0000-0003-3506-578X
Affiliation (Current)	2025: 医療創生大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 摂南大学, 薬学部, 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(薬学系), 特任助教 2015: 徳島大学, 大学院医歯薬学研究部, 特任助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy
Keywords	Principal Investigator 膜透過ペプチド / 粘膜ワクチン / オリゴアルギニン固定化高分子 / 細胞内動態制御 / 核酸DDS / プラスミドDNA / 核酸デリバリー / 遺伝子治療 / G2/M arrest / 核移行 / 抗がん剤 / 遺伝子デリバリー … More Except Principal Investigator … More 膜透過ペプチド / 膜透過ペプチド固定化高分子 / バイオ医薬 / 経粘膜吸収促進 / 経口腔ルート / 非侵襲的投与製剤 / オリゴアルギニン固定化ヒアルロン酸 / タンパク質 / ヒアルロン酸 / タンパク質医薬 / 吸収促進 / ドラッグデリバリーシステム / 感染実験 / 膜透過ペプチド固定化ヒアルロン酸 / オリゴアルギニン固定化高分子 / インフルエンザウイルス / 粘膜免疫 / ワクチン / 自然免疫活性化 / 核酸デリバリー / DDS / リポソーム / Anti-PEG IgM / 免疫 / 核酸 Less

膜透過ペプチド固定化高分子を用いたバイオ医薬の経粘膜投与型製剤の開発
- Principal Investigator
  
  佐久間信至
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Setsunan University
Construction of nasal vaccination system based on co-delivery of antigens and immunostimulants by the polymers bearing cell-penetrating peptides.Principal Investigator
- Principal Investigator
  
  Ukawa Masami
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Setsunan University
Enhancement of mucosal absorption of protein drugs using hyaluronic acid modified with oligoarginines
- Principal Investigator
  
  Sakuma Shinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Setsunan University
Application of the strategy for nucleic acid delivery aimed at remote control of intracellular dynamics to the therapyPrincipal Investigator
- Principal Investigator
  
  Ukawa Masami
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Setsunan University
Mucosal vaccines using oligoarginine-linked polymers that overcome gene diversities of viruses
- Principal Investigator
  
  SAKUMA SHINJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Setsunan University
Establishment of a novel gene delivery strategy targeting tumor utilizing cell cycle arrest caused by antitumor drugsPrincipal Investigator
- Principal Investigator
  
  UKAWA Masami
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Study of immunological response to nucleic acid delivery system
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Acquisition of absorption-enhancing abilities of cationic oligopeptides with short chain arginine residues through conjugation to hyaluronic acid2022
- Author(s)
  Takumi Tomono, Haruya Yagi, Saki Kanemoto, Masami Ukawa, Kohei Miyata, Koichi Shigeno, Shinji Sakuma
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 616 Pages: 121519-121519
- DOI
  10.1016/j.ijpharm.2022.121519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07019
[Journal Article] Biodegradable hyaluronic acid modified with tetraglycine-L-octaarginine as a safe adjuvant for mucosal vaccination2019
- Author(s)
  Masami Ukawa, Sohei Tanishita, Haruya Yagi, Yuki Yoshida, Takumi Tomono, Koichi Shigeno, Etsuo Tobita, Tomofumi Uto, Masanori Baba, Shinji Sakuma
- Journal Title
  
  Mol. Pharmceutics
  
  Volume: 16 Issue: 3 Pages: 1105-1118
- DOI
  10.1021/acs.molpharmaceut.8b01110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08210
[Journal Article] Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.2017
- Author(s)
  Mima, Y., Abu Lila, A.S., Shimizu, T., Ukawa, M., Ando, H., Kurata, Y., Ishida, T.
- Journal Title
  
  J. Control. Release
  
  Volume: 250 Pages: 20-26
- DOI
  10.1016/j.jconrel.2017.01.040
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.2017
- Author(s)
  11.Shimizu, T., Abu Lila, A.S., Nishio, M., Doi, Y., Ando, H., Ukawa, M., Ishima, Y., Ishida, T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 9 Pages: 1864-1869
- DOI
  10.1111/cas.13305
- NAID
  120006535002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] バイオ医薬の口腔内投与製剤の開発を企図したオリゴアルギニン固定高分子の経粘膜吸収促進剤としての有用性評価2023
- Author(s)
  中村篤司、八木晴也、鵜川真実、宮田康平、滋野浩一、佐久間信至
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-22K06569
[Presentation] オリゴアルギニン固定化ヒアルロン酸を用いたバイオ医薬の口腔粘膜吸収促進2021
- Author(s)
  八木晴也，半田悠真，伴野拓巳，鵜川真実，宮田康平，滋野浩一，佐久間信至
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07019
[Presentation] バイオ医薬の経鼻吸収促進剤としての短鎖オリゴアルギニン固定化ヒアルロン酸の有用性評価2021
- Author(s)
  伴野拓巳，八木晴也，金本紗季，鵜川真実，宮田康平，滋野浩一，佐久間信至
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07019
[Presentation] テトラグリシン-L-オクタアルギニン固定化ヒアルロン酸の経直腸吸収促進剤としての有用性評価2021
- Author(s)
  八木晴也，齋藤夏紀，伴野拓巳，鵜川真実，宮田康平，滋野浩一，佐久間信至
- Organizer
  第71回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-19K07019
[Presentation] タンパク医薬の経肺吸収促進を可能にするテトラグリシン-L-オクタアルギニン固定化ヒアルロン酸の特性解析2021
- Author(s)
  八木晴也，伴野拓巳，鵜川真実，宮田康平，滋野浩一，佐久間信至
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-19K07019
[Presentation] 膜透過ペプチドを側鎖に持つヒアルロン酸誘導体を用いたバイオ医薬の経肺デリバリー2020
- Author(s)
  八木晴也、伴野拓巳、鵜川真実、宮田康平、飛田悦男、佐久間信至
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-19K07019
[Presentation] 膜透過ペプチド固定化ヒアルロン酸を粘膜アジュバントとして含有する経鼻粘膜ワクチンの交差反応性のマウス感染実験による実証2019
- Author(s)
  谷下宗平，吉田祐樹，辻岡拓実，鵜川真実，伴野拓巳，宮田康平，飛田悦男，宇都倫史，馬場昌範，佐久間信至
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-16K08210
[Presentation] 膜透過ペプチドを固定化したヒアルロン酸誘導体の粘膜投与型ワクチンのアジュバントとしての特性評価2018
- Author(s)
  八木晴也，谷下宗平，鵜川真実，吉田祐樹，飛田悦男，宇都倫史，馬場昌範，佐久間信至
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-16K08210
[Presentation] オリゴアルギニン固定化高分子によるプラスミドDNAの細胞内取り込みに対するドキソルビシン曝露の影響の検討2018
- Author(s)
  南口遥加，鵜川真実，西野真名仁，飛田悦男，佐久間信至
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08238
[Presentation] 新規粘膜投与型ワクチンのアジュバントとしてのL-オクタアルギニン固定化ヒアルロン酸の開発2018
- Author(s)
  谷下宗平，八木晴也，吉田祐樹，鵜川真実，伴野拓巳，飛田悦男，宇都倫史，馬場昌範，佐久間信至
- Organizer
  創剤フォーラム第24回若手研究会
- Data Source
  KAKENHI-PROJECT-16K08210
[Presentation] Nuclear swelling of cancer cells caused by doxorubicin affected nuclear entry of liposomal pDNA.2017
- Author(s)
  Masami Ukawa, Yuki Kanazawa, Tatsuhiro Ishida
- Organizer
  International Symposium on Drug Delivery and Pharmaceutical Sciences：Beyond the History：ISDDPS
- Place of Presentation
  京都リサーチパーク（京都府京都市）
- Year and Date
  2017-03-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18844
[Presentation] ドキソルビシン処置による核の形質変化が及ぼすDNA封入リポソームの核内移行への影響2016
- Author(s)
  鵜川真実、金沢有希、石田竜弘
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科（愛知県名古屋市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K18844
[Presentation] リポソーム化抗がん剤投与が引き起こす腫瘍免疫細胞の影響2016
- Author(s)
  高山拓磨、清水太郎、鵜川真実、石田竜弘
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] G2/M arrestを引き起こす抗がん剤であるドキソルビシン処置による外来遺伝子発現向上の試み2015
- Author(s)
  金沢有希、高山拓磨、鵜川真実、石田竜弘
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-15K18844

1. SAKUMA SHINJI (80388644)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. ISHIDA Tatsuhiro (50325271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 南川典昭 (40209820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 異島優 (00457590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 清水太郎 (30749388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 安藤英紀 (00735524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 毛利浩太 (30723697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 馬場昌範 (70181039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 伴野拓巳 (30824685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 八木晴也 (20965206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MIYATA kohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. OCHIAI kyohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ukawa Masami 鵜川 真実

UKAWA Masami 鵜川 真実

Research Projects

Research Products

Co-Researchers

膜透過ペプチド固定化高分子を用いたバイオ医薬の経粘膜投与型製剤の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of nasal vaccination system based on co-delivery of antigens and immunostimulants by the polymers bearing cell-penetrating peptides.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Enhancement of mucosal absorption of protein drugs using hyaluronic acid modified with oligoarginines

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of the strategy for nucleic acid delivery aimed at remote control of intracellular dynamics to the therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mucosal vaccines using oligoarginine-linked polymers that overcome gene diversities of viruses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a novel gene delivery strategy targeting tumor utilizing cell cycle arrest caused by antitumor drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of immunological response to nucleic acid delivery system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acquisition of absorption-enhancing abilities of cationic oligopeptides with short chain arginine residues through conjugation to hyaluronic acid2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biodegradable hyaluronic acid modified with tetraglycine-L-octaarginine as a safe adjuvant for mucosal vaccination2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] バイオ医薬の口腔内投与製剤の開発を企図したオリゴアルギニン固定高分子の経粘膜吸収促進剤としての有用性評価2023

Author(s)

Organizer

Data Source

[Presentation] オリゴアルギニン固定化ヒアルロン酸を用いたバイオ医薬の口腔粘膜吸収促進2021

Author(s)

Organizer

Data Source

[Presentation] バイオ医薬の経鼻吸収促進剤としての短鎖オリゴアルギニン固定化ヒアルロン酸の有用性評価2021

Author(s)

Organizer

Data Source

Ukawa Masami 鵜川真実

UKAWA Masami 鵜川真実

[Presentation] 膜透過ペプチドを側鎖に持つヒアルロン酸誘導体を用いたバイオ医薬の経肺デリバリー2020