HANAZAWA Shigemasa 花澤重正

… Alternative Names

HANAWAWA Shigemasa 花澤重正

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Researcher Number	60060258
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012 – 2014: 日本大学, 生物資源科学部, 教授 2005 – 2008: 日本大学, 生物資源科学部, 教授 2004: 九州大学, 歯学研究院, 教授 2002: Kyushu University Faculty of Dental Science, Prof, 歯学研究院, 教授 2000 – 2001: Faculty of Dental Sci. KYUSHU UNIVERSITY Prof., 大学院・歯学研究院, 教授 … More 1998 – 1999: Meikai University School of Dentistry, Prof., 歯学部, 教授 1997: 明海大学, 歯学部, 助教授 1990 – 1994: 明海大学, 歯学部, 助教授 1987: Josai Dental University, Dept. of Oral Microbiology , Assoc. Prof., 歯学部, 助教授 1986: 城西歯大, 歯学部, 助教授 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry / Functional basic dentistry / Fisheries chemistry Except Principal Investigator Morphological basic dentistry / Applied biochemistry
Keywords	Principal Investigator サイトカイン / 遺伝子発現 / TLR / マクロファージ / LPS / P.gingivalis / SOCS / シグナル伝達 / 炎症性サイトカイン / CD14 … More / Signal transduction / Cytokine / 骨芽細胞 / Gene expression / Gingival fibroblasts / 歯周疾患 / 歯肉線維芽細胞 / 細胞内情報伝達 / 相互作用蛋白質 / 相互作用因子 / NF-kB / 肥満 / 成人性歯周病 / Periodontal disease associated bacteria / Monoclonal antibody / 特異精製抗原 / B.gingivalis / 診断学への応用 / 歯周疾患関連細菌 / 単一クローン抗体 / Regulatory mechanisms / Interacting protein / Regulatory molecule / 制御機構 / 抑制因子 / NF-κB / Anti-inflammation / mMacrophage / Leptin / 歯周病 / NFkB / 抗炎症作用 / レプチン / bone resorption / gene expression / active domain / macrophages / recombination / fimbriae / adult periodontitis / Fibronectin / 遺伝子組み換え / レセプター / 骨吸収 / 活性部位 / 遺伝子組換え / 線毛 / Inflammatory cytokine / Lipopolysaccharide / Interleukin-1 / 骨吸収刺激作用 / リポ多多糖体 / リポ多糖体 / Network mechanism / Periodontal tissues / 歯周ポケット / Pgingivalis / 単球走化性因子 / TGT-beat / ネットワーク機構 / 情報伝達 / 歯周組織 / Periodontal disease / Periodonal pathogen / Cytokines / Inflammation / 歯周病病原性細菌 / 炎症 / 蛋白質発現 / 細胞膜透過性蛋白質 / TIPE2 / 細胞膜透過性分子 / 機能発現 / 転写能 / p53 / 細胞膜透過性シグナル分子 / 可視化 / 細胞分化 / 形態形成 / キメラ蛋白質 / シグナル分子 / 細胞膜透過性ペプチド / ゼブラフィッシュ / 炎症学 / 生理活性 / 発現制御 / 感染症 / JAK / STAT / MTM / 細胞膜透過性 / IRAK-M / 蛋白質療法 / 口腔細菌学 / RNAi干渉 / siRNA / RNA干渉 / SOCS-3 / 炎症反応 / プロテオーム解析 / 細菌成分 / 制御因子 / MALD-TOF / 転写調節 / リポ多糖 … More Except Principal Investigator P.gingivalis / 歯周疾患 / 線毛 / Vaccination / Inflammation / Bone resorption / Fimbriae / サイトカイン / P..gingivalis / ワクチン / 炎症 / 骨吸収作用 / タンパク質分解耐性 / Sirt / 長寿 / Treg分化 / 細胞膜透過性タンパク質 / RAR / 細胞分化調節 / 細胞膜透過性 / Sox17 / HNF3β / Foxp3 / 肝細胞分化 / Treg / 制御性T細胞 / iPS細胞 / Stabilon / 細胞機能調節 / 細胞分化制御 / 膜透過性タンパク質 / スタビロン / 分解耐性 / 遺伝子発現 / 炎症性サイトカイン / 歯周組織 / 能動免疫 / 受動免疫 Less

Development of controlling system of cell differentiation/life by proteolysis resistant cell-permeable protein
- Principal Investigator
  
  MASUHIRO Yoshikazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Nihon University
Development of a novel technology to introduce signal transduction molecules into zebrafish embryo using membrane-translocating motifPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Nihon University
A fundamental study about development of the protein therapy using suppressors of TLR signalingPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
サイトカインシグナル抑制因子の新規機能の解析に関するRNA干渉法の応用Principal Investigator
- Principal Investigator
  
  花澤重正
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Molecular regulatory mechanism of suppressor of cytokine signaling (SOCS) in TLR signalingPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
MALD-TOF法によるTLRシグナル分子相互作用蛋白質の検索法の開発Principal Investigator
- Principal Investigator
  
  花澤重正
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
  Kyushu University
Molecular mechanism of anti-inflammatory action of leptin in periodontal diseasePrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemas
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
歯周疾患病原性細菌の病原性機構における飽食因子レプチンの制御作用Principal Investigator
- Principal Investigator
  
  花澤重正
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Identification and application of functional active domain of P.gingivalis fimbriaePrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Morphological basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
  Meikai University
P．gingivalis線毛免疫による歯周組織破壊に関する防御機構の解析
- Principal Investigator
  
  KITANO Shigeo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Role of CD14 on human gingival fibroblasts in pathogenesis of periodontal diseasePrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
P.gingivalis線毛の成人型歯周疾患ワクチンへの応用に関する基礎的研究
- Principal Investigator
  
  KITANO Shigeo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Gene expression of inflammatory cytokines in periodontal tissues and network of thier cytokinesPrincipal Investigator
- Principal Investigator
  
  HANAWAWA Shigemasa
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University, School of Dentistry
Regulation of Cytokines for Gene Expression and Function of Gingival FibroblastsPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Miekai University School of Dentistry
Application for diagnosis of B.gingivalis-specific monoclonal antibody in periodontal disease.Principal Investigator
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Josai dental University, Dept. of Oral Microbiology

All 2015 2014 2013 2012 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

[Journal Article] Adiponectin inhibits induction of TNF-alpha/RANKL-stimulated NFATcl via the AMPK signaling.2008
- Author(s)
  Yamaguchi N, Kukita T, Li YJ, Kamio N, Fukumoto S, Nonaka K, Ninomiya Y, Hanazawa S, Yamashita Y
- Journal Title
  
  FEBS Letter 582
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659543
[Journal Article] Adiponectin inhibits induction of TNF-alpha/RANKL-stimulated NFATc1 via the AMPK signaling.2008
- Author(s)
  Yamaguchi N, Kukita T, Li YJ, Kamio N, Fukumoto S, Nonaka K, Ninomiya Y, Hanazawa S, Yamashita Y
- Journal Title
  
  FEBS Letter 582
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390467
[Journal Article] SOCS-3 inhibits E2F/DP-1 transcriptional activity and cell cycle progression via interaction with DP-12008
- Author(s)
  舛廣善和、嘉山謙一、福島晶絵、馬場孝治、双津牧雄、上谷能彬、後藤道雄、山口登、花澤重正
- Journal Title
  
  The Journal of Biological Chemistry 283
  
  Pages: 31575-31583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390467
[Journal Article] Adiponectin inhibits induction of TNF-alpha/RANKL-stimulated NFATc1 via the AMPK signaling2008
- Author(s)
  山口登、神尾宜昌、福本敏、野中和明、二ノ宮裕三、花澤重正、山下喜久、その他2名
- Journal Title
  
  FEBS Lett 582
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390467
[Journal Article] Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.2007
- Author(s)
  Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.
- Journal Title
  
  FEMS Immunol. Med. Microbiol. 49(1)
  
  Pages: 28-34
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.2007
- Author(s)
  Yamaguchi N, Hanazawa S, 他5名
- Journal Title
  
  FEMS Immunol. Med. Microbiol. 49(1)
  
  Pages: 28-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.2007
- Author(s)
  Yamaguchi N, Hanazawa S. et al.
- Journal Title
  
  FEMS Immunol.Med.Microbiol. 49(1)
  
  Pages: 28-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] An ortho dimer of butylated hydroxyanisole inhibits nuclear factor kappa B activation and gene expression of inflammatory cytokines in macrophages stimulated by Porphyromonas gingivalis fimbriae2006
- Author(s)
  Murakami Y, Shoji M, Hirata A, Tanaka S, Hanazawa S, Yokoe I, Fujisawa S.
- Journal Title
  
  Arch. Biochem. Biophys. 449(1-2)
  
  Pages: 171-177
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Induction of Porphyromonas gingivalis GroEL signaling via binding to Toll-like receptors 2 and 4.2006
- Author(s)
  Argueta JG, Shiota S, Yamaguchi N, Masuhiro Y, Hanazawa S.
- Journal Title
  
  Oral Microbiol Immunol 21(4)
  
  Pages: 245-251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Induction of Porphyromonas gingivalis GroEL signaling via binding to Toll-like receptors 2 and 4.2006
- Author(s)
  Argueta JG, Shiota S, Yamaguchi N, Masuhiro Y, Hanazawa S
- Journal Title
  
  Oral Microbiol Immunol. 21(4)
  
  Pages: 245-251
- Data Source
  KAKENHI-PROJECT-18659543
[Journal Article] Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.2006
- Author(s)
  Yamaguchi N, Kukita T, Li YJ, Martinez, Argueta JG, Saito T, Hanazawa S, Yamashita Y
- Journal Title
  
  FEMS Immunol. Med. Microbiol. 49(1)
  
  Pages: 28-34
- Data Source
  KAKENHI-PROJECT-18659543
[Journal Article] Induction of Porphyromonas gingivalis GroEL signaling via binding to Toll-like receptors 2 and 4.2006
- Author(s)
  Argueta JG, Shiota S, Yamaguchi N, Masuhiro Y, Hanazawa S.
- Journal Title
  
  Oral Microbiol Immunol. 21(4)
  
  Pages: 245-251
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Identification and characteri-zation of novel isoforms of human DP-1 : DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner.2005
- Author(s)
  Ishida H, Masuhiro Y, Fukushima A, Argueta J amaguchi N, Shiota S, Hanazawa S.
- Journal Title
  
  J.Biol.Chem. 280・26
  
  Pages: 6821-6826
- Data Source
  KAKENHI-PROJECT-16659500
[Journal Article] Adiponectin inhibits Toll-like receptor family-induced signaling.2005
- Author(s)
  Yamaguchi N, Hanazawa S. et al.
- Journal Title
  
  FEBS Lett. 579(30)
  
  Pages: 6821-6826
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Splicing potentiation by growth factor signals via estrogen receptor phosphorylation.2005
- Author(s)
  Masuhiro Y, Mezaki Y, Sakari M, Takeyama K, Yoshida T, Inoue K, Yanagisawa J, Hanazawa S. O'malley BW, Kato S.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102/23
  
  Pages: 8126-8131
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Identification and characterization of novel isoforms of human DP-1:DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner.2005
- Author(s)
  Ishida, H., Masuhiro, Y., Hanazawa, S.et al.
- Journal Title
  
  J.Biol.Chem. 280(26)
  
  Pages: 24642-24648
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Adiponectin inhibits Toll-like receptor family-induced signaling.2005
- Author(s)
  Yamaguchi N, Argueta JG, Masuhiro Y, Kagishita M, Nonaka K, Saito T, Hanazawa S, Yamashita Y.
- Journal Title
  
  FEBS Lett. 579・30
  
  Pages: 6821-6826
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Adiponectin inhibits Toll-like receptor family-induced signaling.2005
- Author(s)
  Yamaguchi N.Argueta JG, Masuhiro Y, Kagishita M, Nonaka K, Saito T, Hanazawa S.Yamashita Y.
- Journal Title
  
  FEBS Lett. 579・30
  
  Pages: 6821-6826
- Data Source
  KAKENHI-PROJECT-16659500
[Journal Article] Identification and characteri- zation of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner.2005
- Author(s)
  Ishida H, Masuhiro Y, Fukushima A, Argueta JG, Yamaguchi N, Shiota S, Hanazawa S.
- Journal Title
  
  J.Biol.Chem. 280・26
  
  Pages: 24642-24648
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Splicing potentiation by growth factor signals via estrogen receptor phosphorylation.2005
- Author(s)
  Masuhiro Y, Mezaki Y, Sakari M, Takeyama K, Yoshida T, Inoue K, Yanagisawa J, Hanazawa S, O'malley BW, Kato S.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102・23
  
  Pages: 8126-8131
- Data Source
  KAKENHI-PROJECT-16659500
[Journal Article] Interleukin-6 negatively regulates Porphyromonas gingivalis fimbria-stimulated fibronectin expression in human gingival fibroblasts.2005
- Author(s)
  Murakami Y, Shoji M, Hirata A, Tanaka S, Hanazawa S, Fujisawa S.
- Journal Title
  
  FEMS Immunol.Med.Microbiol. 43・2
  
  Pages: 205-211
- Data Source
  KAKENHI-PROJECT-16659500
[Journal Article] Adiponectin inhibits Toll-like receptor family-induced signaling.2005
- Author(s)
  Yamaguchi N, Hanazawa S 他5名
- Journal Title
  
  FEBS Lett. 579(30)
  
  Pages: 6821-6826
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Identification and characterization of novel isoforms of human DP-1 : DP-1 {alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner.2005
- Author(s)
  Ishida, H., Masuhiro, Y., Hanazawa, S.他4名
- Journal Title
  
  J.Biol.Chem 280(26)
  
  Pages: 24642-24648
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390488
[Journal Article] Tumor necrosis factor alpha enhances Actinobacillus actinomycetemcomitans leukotoxin-induced HL-60 cell apoptosis by stimulating lymphocyte function-associated antigen 1 expression2004
- Author(s)
  Yamaguchi N, Kubo C, Masuhiro Y, Lally ET, Koga T, Hanazawa S.
- Journal Title
  
  Infect.Immun. 72・1
  
  Pages: 269-276
- Data Source
  KAKENHI-PROJECT-16659500
[Patent] 白血病治療に応用可能な細胞膜透過性タグおよび核移行シグナル融合RARαタンパク質の大量発現系、精製系の確立2009
- Inventor(s)
  花澤重正、舛廣善和
- Industrial Property Rights Holder
  日本大学
- Industrial Property Number
  2009-077375
- Filing Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390467
[Patent] 白血病治療に応用可能な細胞膜透過性タグおよび核移行シグナル融合 RARαタンパク質の大量発現系、精製系の確立2009
- Inventor(s)
  花澤重正, 舛廣善和
- Industrial Property Rights Holder
  日本大学
- Industrial Property Number
  2009-077375
- Filing Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] Stabilon融合タンパク質を用いたiPS細胞から肝細胞への分化誘導法の確立2015
- Author(s)
  峰岸紋子、相原絵理、細野崇、舛廣善和、花澤重正、関泰一郎
- Organizer
  日本農芸化学会2015年度岡山大会
- Place of Presentation
  岡山大学津島キャンパス（岡山県・岡山市）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] 膜貫通性リコンビナントGemininタンパク質は、造血幹細胞の自己複製と細胞分化を制御する新たなストラテジーを提供するだろう2014
- Author(s)
  大野芳典、安永晋一郎、竹立恭子、山藤幹茂子、舛廣善和、花澤重正、大坪素秋、瀧原義宏
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] TIPE2はTAK1を介するH.pylori CagAシグナルを負に制御する2014
- Author(s)
  中野利沙、櫻井渉、大穗満隆、松本翔太、宮本梓、舛廣善和、花澤重正
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] 分解耐性型細胞膜透過性タンパク質を用いた遺伝的に安全な細胞機能／分化調節系の開発　～分解耐性モチーフStabilonの応用～2013
- Author(s)
  舛廣善和、石井承子、宮寺真、寺沢達哉、峰岸紋子、花澤重正
- Organizer
  第８回日本大学先端バイオフォーラム
- Place of Presentation
  東京、市ヶ谷、日本大学本部大講堂
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] 細胞膜透過性SOCS2タンパク質によるGHシグナルの抑制2013
- Author(s)
  宮本梓、小林笑久未、舛廣善和、花澤重正
- Organizer
  第８回日本大学先端バイオフォーラム
- Place of Presentation
  東京、市ヶ谷、日本大学本部大講堂
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] TIPE2によるTAK1を介したシグナル抑制に関する研究報告2013
- Author(s)
  櫻井渉、鈴木範子、中野利沙、舛廣善和、花澤重正
- Organizer
  第８回日本大学先端バイオフォーラム
- Place of Presentation
  東京、市ヶ谷、日本大学本部大講堂
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] ゼブラフィッシュ胚における細胞膜透過性シグナル分子導入法2012
- Author(s)
  増見健太郎、今村　伸太朗、薮　健史、舛廣　善和、山下　倫明、花澤　重正
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24580308
[Presentation] 遺伝子組換え型細胞膜透過性RARαの発現系の確立と前骨髄球性白血病細胞に関する分化誘導作用2009
- Author(s)
  稲垣みずき、舛廣善和、関泰一郎、有賀豊彦、花澤重正、その他4名
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] 細胞膜透過性タグ融合サイトカインシグナル抑制因子SOCS-2の大腸菌による発現系の確立2009
- Author(s)
  舛廣善和、佐藤あまね、石黒友理、花澤重正
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] サイトカインシグナル抑制因子SOCS-7の新規機能の解析; TRIAD3はSOCS-7の新たな相互作用因子である2009
- Author(s)
  尾勝圭、舛廣善和、小島裕久、花澤重正
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] 細胞周期調節性転写因子DP-1のプロテアソームを介する分解機構; その分解制御領域Stabilon及びDegronの同定2009
- Author(s)
  荒川貴史、舛廣善和、上谷能彬、花澤重正
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] Erk2によるヒトSOCS-3のS159のリン酸化とJAK-STATシグナル伝達系制御2008
- Author(s)
  双津牧雄、舛廣善和、渡邊希、花澤重正
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] 細胞周期調節性転写因子DP-1のプロテアソーム系を介する自己分解機構2008
- Author(s)
  上谷能彬、舛廣善和、荒川貴史、花澤重正
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] SOCS-7はNF-κBシグナル活性化因子TRIP6と相互作用しそのシグナルを負に制御する2008
- Author(s)
  小島裕久、舛廣善和、花澤重正
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] SOCS-3とDP-1の相互作用による細胞周期調節機構の解析2008
- Author(s)
  舛廣善和、双津牧雄、馬場孝治、花澤重正
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390467
[Presentation] TIPE2(TNF-α-induced protein 8-like 2)のTAK1シグナルに関する負の制御とその機構
- Author(s)
  大穗満隆、櫻井渉、中山隆太郎、小川裕子、舛廣善和、花澤重正
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] 細胞膜透過性TIPE2はIn vivoにおけるTLR4シグナル伝達を抑制する
- Author(s)
  中山隆太郎、大穗満隆、櫻井渉、宮本梓、舛廣善和、花澤重正
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24580148
[Presentation] 膜貫通性リコンビナントGemininタンパク質は、造血幹細胞の自己複製と細胞分化を制御する新たなストラテジーを提供するだろう
- Author(s)
  黒木利知、大野芳典、安永晋一郎、竹立恭子、山藤幹茂子、舛廣善和、花澤重正、大坪素秋、瀧原義宏
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2014-11-24 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24580308
[Presentation] TIPE2はTAK1を介するH.pylori CagAシグナルを負に制御する
- Author(s)
  中野利沙、櫻井渉、大穗満隆、松本翔太、宮本梓、舛廣善和、花澤重正
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2014-11-24 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24580308

1. MASUHIRO Yoshikazu (00336083)

# of Collaborated Projects: 6 results

# of Collaborated Products: 32 results
2. TAKESHITA Akira (70236454)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. AMANO Shigeru (90167958)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. KIKUCHI Hirotaka (70234193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KITANO Shigeo (30049374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SHIMOKAWA Osamu (40136502)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OHMORI Yshihiro (50194311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SHIOTA Susumu (00150467)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SEKINE Keisuke (00323569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SEKI Taiichirou (20187834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. YABU Takeshi (00551756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IMAMURA Shintarou (80510007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. MURAKAMI Yukio (00286014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAGUCHI Noboru (00230368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
15. 中野善夫 (80253459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 斉藤貴江子 (10162190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 三好武仁 (90174226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HANAZAWA Shigemasa 花澤 重正

HANAWAWA Shigemasa 花澤 重正

Research Projects

Research Products

Co-Researchers

Development of controlling system of cell differentiation/life by proteolysis resistant cell-permeable protein

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Development of a novel technology to introduce signal transduction molecules into zebrafish embryo using membrane-translocating motifPrincipal Investigator

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A fundamental study about development of the protein therapy using suppressors of TLR signalingPrincipal Investigator

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サイトカインシグナル抑制因子の新規機能の解析に関するRNA干渉法の応用Principal Investigator

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Molecular regulatory mechanism of suppressor of cytokine signaling (SOCS) in TLR signalingPrincipal Investigator

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MALD-TOF法によるTLRシグナル分子相互作用蛋白質の検索法の開発Principal Investigator

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Molecular mechanism of anti-inflammatory action of leptin in periodontal diseasePrincipal Investigator

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歯周疾患病原性細菌の病原性機構における飽食因子レプチンの制御作用Principal Investigator

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Identification and application of functional active domain of P.gingivalis fimbriaePrincipal Investigator

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P．gingivalis線毛免疫による歯周組織破壊に関する防御機構の解析

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Role of CD14 on human gingival fibroblasts in pathogenesis of periodontal diseasePrincipal Investigator

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P.gingivalis線毛の成人型歯周疾患ワクチンへの応用に関する基礎的研究

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Gene expression of inflammatory cytokines in periodontal tissues and network of thier cytokinesPrincipal Investigator

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HANAZAWA Shigemasa 花澤重正

HANAWAWA Shigemasa 花澤重正