KUBA Kenji 久場健司

Researcher Number	60080561
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Affiliation (based on the past Project Information) *help	2010: Nagoya University of Arts and Sciences, 栄養学部, 教授 2006 – 2009: 名古屋学芸大学, 管理栄養学部, 教授 1996 – 2001: Nagoya University, School of Medicine, Professor, 医学部, 教授 1986 – 1995: 佐賀医科大学, 医学部, 教授 1992 – 1994: 佐賀医大, 医学部, 教授 … More 1986: 佐賀医大, 医学部, 教授 1986: 佐賀医科大学, 教授 1985: 佐賀医科大学, 医, 教授 Less
Review Section/Research Field	Principal Investigator General physiology / General physiology / 神経・脳内生理学 / Neurophysiology and muscle physiology / 神経・筋肉生理学 Except Principal Investigator General physiology / 分子遺伝学・分子生理学 / Neurophysiology and muscle physiology / 神経・脳内生理学 / 生理学一般
Keywords	Principal Investigator 細胞内Ca^<2+> / Intracellular Ca^<2+> / ウシガエル交感神経節細胞 / Ca^<2+>誘起性Ca^<2+>遊離 / Ca^<2+>遊離 / 交感神経節細胞 / Presynaptic terminals / ミトコンドリア / 可塑性 / シナプス前終末 … More / 紫外レ-ザ- / ウシガエル交換神経節細胞 / Ryanodine receptor / 長期増強 / 開口放出 / カエル運動神経終末 / 短期可塑性 / ライアノジン受容体 / Ca^<2+>依存性K^+チャンネル / 二光子励起 / ニューロン / 超短パルスレーザー / Ca^<2+>チャネル / インド-1 / Ca^<2+>遊離チャネル / アセチルコリン / 容量性Ca^<2+>流入 / 滑面小胞体 / 褐色脂肪細胞 / 運動神経終末 / 伝達物質放出 / グルタミン酸受容体 / Ca^<2+>チャンネル / 共焦点レ-ザ-顕微鏡 / 共焦点顕微鏡 / 海馬ニュ-ロン / -adrenoceptor / Cyclic GMP / Cyclic AMP / Adrenaline / Transmitter release / Long-term potentiation / Bullfrog sympathetic ganglion / ACh放出促進 / ウシガエル交感神経節 / ベータアドレナリン受容体 / 短期促進 / シナプスの可塑性 / βーアドレナリン受容体 / サイクリックGMP / サイクリックAMP / 脱感作 / アドレナリン / energy balance / α1 receptor / β3receptor / Capacitative Ca^<2+> entry / Ca^<2+> release / endoplasmic reticulum / Mitochondria / Brown adipocyte / ノルアドレナリン / 脱共役 / カルシウムイオン / α1受容体 / エネルギーバランス / α_1受容体 / β_3受容体 / Bullfrog sympathetic panglion cell / Short-term plasticity / Exocytosis / Intracellular Ca^<2+> release / Frng motor nerve terminal / Ca^<2+> -dependent K^+ channel / Total fluorescence collecting-two photon laser scanning microscope / カゴメ化合物活性化 / 細胞内Ca^<2+>遊離 / ティアノジン受容体 / Ca^<2+>依存性K^+チャネル / 全方位蛍光集光2光子励起レーザー顕微鏡 / plasticity / Transmitter exocytosis / Action potential / CaィイD12+ィエD1-dependent KィイD1+ィエD1 channel / CaィイD12+ィエD1 release / CaィイD12+ィエD1 channel / Ca^<2+>蛍光プローブ / 光軸方向解像度 / 空間解像度 / レーザー顕微鏡 / ニコチン性シナプス / シナプス可塑性 / カエル神経筋接合部 / 同期的興奮 / 電位依存性Ca^<2+>チャンネル / シナプス前経末 / 伝達物質開口放出 / 活動電位 / リアノジン受容体 / Postnatal development / Muscarinic receptors / Glutamate receptors / Plasticity / Neurotransmitters / Synapses / 生後発達 / マスカリン受容体 / 神経伝達物質 / シナプス / Fluorescent measurement / Ti-Sapphire laser / Indo-1 / Neurons / Pulsed laser / Two photon excitation / 細胞内Ca^<2+>遊離機構 / ニューロン内Ca^<2+>イメージ / Ca^<2+>感受性蛍光プローブ / 共焦点走査装置 / 起短パルスレーザー / 蛍光測定 / チタンサファイアレーザー / 2光子励起 / Mitochondria Cyclosporin-A / Cylic ADP-ribose / Rabbit otic ganglion cells / Bullfrog sympathetic ganglion cells / Ca^<2+> influx / Ca^<2+> -induced Ca^<2+> release / パッチクランプ法 / 紫外レーザー共焦点顕微鏡法 / 落射蛍光法 / Ca^<2+>感受性プローブ / cyclic ADP-ribose / サイクロスポリンA / Cyclic ADP-ribose / ウサギ耳神経節細胞 / Ca^<2+>電流 / Ca^<2+>誘起性CA^<2+>遊離 / Ca^<2+>-channel / Sympathetic ganglion cells / Ca^<2+>-release channel / Ca^<2+>-induced Ca^<2+> release / Indo-l / Laser-scanning microsope / Ultraviolet laser / Ca^<2+>-チャンネル / 蛍光プロ-ブ / 神経細胞 / Ca^<2+>-誘起性Ca^<2+>遊離 / 紫外レーザー共焦点顕微鏡 / 細胞内Ca^<2+>貯蔵部位 / 紫外レ-ザ-共焦点顕微鏡 / Neural differentiation / Second messenger / Kinase / Transmitter / Modulator / Ion channel / Excitable membranes / イオンチャネルの開閉制御 / イオン透過 / 骨奮性細胞 / 急速外液交換技術 / 神経分化 / 二次メッセンジャ- / リン酸化酵素 / 伝達物質 / モジュレ-タ- / イオンチャネル / 興奮性膜 / 單一チャネル電流 / Ach-チャネル / Ach受容体 / UCP蛋白 / 高脂肪食 / 胆汁酸 / 肥満 / 細胞内Ca / アドレナリン受容体 / β_3受容体活性 / 交感神経節 / プライミング / GABA受容体チャネル / グルタミン酸受容体チャネル / Ca^<2+>誘起性Ca^<2+>遊離チャネル / 中隔野ニューロン / 海馬ニューロン / 電位依存性Ca^<2+>誘起性Ca^<2+>遊離 / 中隔野ニュ-ロン / 多シナプス入力 / 細胞体 / 樹状突起 … More Except Principal Investigator 可塑性 / 長期増強 / シナプス / カルシウム / イオンチャネル / 細胞内情報伝達 / 電気生理学 / 細胞膜 / Physiology / Magnesium / 細胞生物学 / 生理学 / マグネシウム / カルモジュリン依存性キナーゼ / Second messenger / Receptor / カルシウムイオン / ホルモン / 伝達物質 / 発芽 / レセプター / シナプス伝達 / Kチャネル / 蛋白質リン酸化 / 核 / 膜融合 / Neuronal differentiation / Intracellular Ca / Ca-influx / Cell membrane signaling / Channel gating / Ionic channel / イオン電流 / 興奮性膜 / Caチャネル / Naチャネル / 神経分化 / 細胞内Ca / Ca流入 / セカンドメッセンジャ- / 細胞シグナル / 受容体 / チャネルゲ-ト機構 / protein kinese / calmodulin / quantal content / calcium ion / long-term potentiation / synaptic transmission / ジアシルグリセロール / Cキナーゼ / 量子数 / 交感神経節 / 長期促進 / IAP / JSTX / glutamate receptor / pancreatic B cell / squid giant axon / dorsal root ganglion cell / Cl^--channel / Ca^<2+>-activated K^+-channel / K輸送 / Na / 【Ca^(2+)】感受性イオンチャネル / Nalk輸送 / ホヤ胚 / 膵β細胞 / ムスカリン性受容体 / グルタミン酸受容体 / ゲート機構 / Ca^<2+>感受性イオンチャネル / 膜電位依存性イオンチャネル / Nuclear Magnetic Resonance / Pathophysiology / Cell Biology / Electrophysiology / イオントランスポート / 核磁気共鳴 / 病態生理学 / Ciliary muscle / CRTR / Tautomycin / Microcystins / Okadaic acid / Signal transduction / Protein phosphorylation / Protein phosphatases / 酵素阻害剤 / ト-トマイシン / 毛様体筋 / CFTR / トートマイシン / ミクロシスチン / オカダ酸 / 信号伝達 / 蛋白質燐酸化 / プロテインフォスファターゼ / Calcium channels / Cell biology / カルシウムチャネル / CALMODULIN DEPENDENT PROTEIN KINASE / INTRACELLULAR Ca^<2+> / PATCH CLUMP / MINIATURE EXCITATORY POSTSYNAPTIC CURRENTS / NICOTINIC ACETYLCHOLINE / PERIPHERAL NEURONS / PLASTICITY / 細胞内Ca^<2+> / パッチクランプ / 微小シナプス後電位 / ニコチン性アセチルコリン / 末梢神経 / シナプス可塑性 / Phosphorilation of protein / Intracellular calcium / Cross talk / Hydrolysis of membrane lipid / Ion Channel / 神経細胞 / 生体電気シグナル / cDNA / mRNA / 蛋白リン酸化 / 細胞内カルシウム / 膜脂質代謝 / クロストーク / セカンドメッセンジャー / 成長因子 / エストロゲン / 蛋白質リン酸化酵素 / サイクリックAMP / 条件反射 / GABA / アセチルコリン / 感覚受容 / トランスダクション / 情報変換 / ケイジ化合物 / イメージング / 2光子励起 / 視覚野 / 大脳視覚野 / 海馬 / 虚血 / 長期抑圧 / 細胞死 / 神経変性 / イメージング生理学 / 連合学習 / インフォメーションフロー / カルシウムチャンネル / アクチブゾーン / リサイクリング / 脱リン酸化 / シナプス小胞 / レキナーゼ / タンパク質リン酸化 / プレシナプス / Caチヤネル / シナプス小脳 / トランスミッター / シナプシン / 伝達物質放出 / Ca_<2+>チャネル / 低分子量Gタンパク / プレシナプスモデル / イメ-ジング生理学 / 光学顕微鏡技術 / インフォメ-ションフロ- / 蛍光顕微測光システム / 伝達物質の放出 / インパルス伝達 Less

褐色脂肪細胞のアドレナリン受容体シグナリングの肥満発症と予防における役割Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University of Arts and Sciences
Bimodal Regulation of Plasmalemmal Ca2+ entry by the coupling of mitochondria and the endoplasmic reticulumPrincipal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University of Arts and Sciences
シナプス前終末の可塑的な細胞内Ca^<2+>遊離機構と伝達物質放出Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  神経・脳内生理学
- Research Institution
  Nagoya University
細胞内情報伝達ネットワーク研究のための2光子励起法適用可能な機能探索分子
- Principal Investigator
  
  NAKAYAMA Shinsuke
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
Physiological Relevance ofIntracellular Magnesium
- Principal Investigator
  
  NAKAYAMA Shinsuke
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
Development of a total fluorescence collecting-two photon laser scanning microscope and analysis of intracellular Ca^<2+> dynamicsPrincipal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
Physiological Relevance of Intracellular Magnesium
- Principal Investigator
  
  NAKAYAMA Shinsuke
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
Intracellular distribution and regulatory function of protein phosphatases
- Principal Investigator
  
  TAKAI Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
A Study on intra uPrincipal Investigator
- Principal Investigator
  
  KUBA Konji
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  NAGOYA UNIVERSITY
CREATION OF NEW CONCEPT AND ITS MECHANISM IN SYNAPTIC PLASTICITY AT CHOLINERGIC SYNAPSES
- Principal Investigator
  
  SHIRASAKI Tetsuya
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  KANSAI MEDICAL UNIVERSITY
  佐賀医科大学
神経活動によるシナプスの抑圧・退行のメカニズム
- Principal Investigator
  
  川合述史
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Jichi Medical University
Physiological studies on the mechanisms of synaptic transmission.Principal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Nagoya University
  佐賀医科大学
神経伝達物質放出の調節機構
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
The development of a two photon laser-scanning confocal microscope and its application to intracellular Ca^<2+> measurementPrincipal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
  佐賀医科大学
異種のタタシナプス入力に対する海馬ニューロンの応答様式Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  佐賀医科大学
細胞膜から核へのインフォメーションフローに関する総合的研究
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kyushu University
THE CROSS TALK OF SIGNAL TRANSMISSION BETWEEN THE RECEPTOR AND THE CHANNEL
- Principal Investigator
  
  AKAIKE Norio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生理学一般
- Research Institution
  KYUSYU UNIVERSITY
  Tohoku University
A study on the mechanism of intracellular Ca^<2+> release in neurones and its physiological functions.Principal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  神経・筋肉生理学
- Research Institution
  Saga Medical School
異種の多シナプス入力に対する海馬ニュ-ロンの応答とその統合理論Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  佐賀医科大学
細胞膜から核へのインフォメ-ションフロ-に関する総合的研究
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kyushu University
Ultraviolet laser-scanning confocal microscopy and application to the measurement of intracellular Ca^<2+>Principal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
異種の多シナプス入力に対する海馬ニュ-ロンの応答とその統合理論Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  佐賀医科大学
Modulators of ion permeation across the biological membranesPrincipal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
「脳・神経細胞におけるインパルス・シグナリングの分子機構」
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
シナプスの可塑性
- Principal Investigator
  
  山本長三郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kanazawa University
Signal transduction and ionic movement of cell membrane
- Principal Investigator
  
  TOMITA Tadao
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  General physiology
- Research Institution
  Nagoya University, School of Medicine
MECHANISM OF THE LONG-TERM POTENTIATION OF TRANSMITTER RELEASE IN BULLFROG SYMPATHETIC GANGLIA.
- Principal Investigator
  
  MINOTA Shoichi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  SAGA MEDICAL SCHOOL
イオンチャンネル開閉のダイナミックス
- Principal Investigator
  
  木島博正
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
シナプスの可塑性
- Principal Investigator
  
  山本長三郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kanazawa University
シナプスの可塑性
- Principal Investigator
  
  山本長三郎
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kanazawa University
Ion Channel and Cellular Metabolism
- Principal Investigator
  
  KITASATO Hiroshi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  General physiology
- Research Institution
  Shiga University of Medical Science
Long-term regulation of neurotransmitter by adrenalinePrincipal Investigator
- Principal Investigator
  
  KUBA Kenji
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Saga Medical School
神経細胞のアセチルコリン受容体チャネルの開閉機構とCa^<2+>による可塑的制御Principal Investigator
- Principal Investigator
  
  久場健司
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  佐賀医科大学

All 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 標準生理学、第7版、第3章興奮の伝達(小澤他偏)2009
- Author(s)
  久場健司(分担執筆)
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20590221
[Journal Article] Ca2+-dependent inactivation of Ca2+-induced Ca2+ release in bullforg sympathetic neurons2008
- Author(s)
  Akita, T & Kuba, K.
- Journal Title
  
  Journal of Physiology 586
  
  Pages: 3365-3384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590221
[Journal Article] Bidirectional Ca^<2+>- coupling of mitochondria with the end oplasmic reticulum and regulation of multimodal Ca^<2+> entries in rat brown adipocytes2007
- Author(s)
  Kuba, M., Higure, Y., Susaki, H., Hayato, R. and Kuba, K.
- Journal Title
  
  Amer. J. Physiol. 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Functional Ca^<2+>-coupling among mitochondrion, endoplasmic reticulum and plasmalemma in thermogenic brown adipocytes : Possible roles in energy consumption.2007
- Author(s)
  Kuba, M., Higure, Y., Hayato, R., Susaki, H., Kuba, K.
- Journal Title
  
  Annual Report of Institute of Health and Nutrition, Nagoya University of Arts and Sciences. 1
  
  Pages: 41-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Bidirectional Ca^<2+> coupling of mitochondria With the endoplasimic reticulum and regulation of multimodal Ca^<2+> entries in rat brown adipocytes2007
- Author(s)
  Kuba, M.
- Journal Title
  
  American Journal of Physiology, Cell Physiology 292
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] (2007) Enhancement of Ca^<2+>-induced Ca^<2+> release by cyclic ADP-ribose in frog motor nerve terminals.2007
- Author(s)
  Hachisuka, J., Soga-Sakakibara, S., Kubota, M., Narita, K. Kuba, K.
- Journal Title
  
  Neuroscience. 146
  
  Pages: 123-131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Enhancement of Ca^<2+>-induced Ca<2+> release by cyclic ADP-ribose in frog motor nerve terminals.2007
- Author(s)
  Hachisuka, J., Soga-Sakakibara, S., Kubota, M., Narita, K. Kuba, K.
- Journal Title
  
  Neuroscience 146
  
  Pages: 123-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca^<2+> signalling in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida, H., Bowden, S. E. H., Yokoyama, S. Salmina, A., Hashii, M., Hoshi, N., Zhang, J.-S., Knyjnik, R., Noda, M., Zhong, Z. G., Jin, D., Higashida, K., Takeda, H., Akita, T., Kuba, K., Yamagishi, S., Shimizu, N., Takasawa, S., Okamoto, H., Robbins, J.
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- NAID
  10024413034
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Bidirectional Ca^<2+>-coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca^<2+> entries in rat brown adipocytes2007
- Author(s)
  Kuba, M., Higure, Y., Susaki, H., Hayato, R. and Kuba, K.
- Journal Title
  
  Amer.J.Physiol. 292
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetyl choline-induced Ca^<2+> signalling in rodent NG108-15 neuroblastoma cells2007
- Author(s)
  Higashida, H., Bowden, S.E.H., Yokoyama, S. Salmina, A., Hashii, M., Hoshi, N., Zhang, J.-S., Knyjnik, R., Noda, M., Zhong, Z.G., Jin, D., Higashida, K., Takeda, H., Akita, T., Kuba, K., Yamagishi, S., Shimizu, N., Takasawa, S., Okamoto, H. and Robbins, J.
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- NAID
  10024413034
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Functional Ca^<2+>-coupling among mitochondrion,endoplasmic reticulum and plasmalemma in thermogenic brown adipocytes:Possible roles in energy consumption2007
- Author(s)
  Kuba, M., Higure, Y., Hayato, R., Susaki, H.and Kuba, K.
- Journal Title
  
  Annual Report of Institute of Health and Nutrition, Nagoya University of Arts and Sciences 1
  
  Pages: 41-54
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Enhancement of Ca^<2+>-induced Ca^<2+> release by cyclic ADP-ribose in frog motor nerve terminals2007
- Author(s)
  Hachisuka, J., Soga-Sakakibara, S., Kubota, M., Narita, K. Kuba, K.
- Journal Title
  
  Neuroscience 146
  
  Pages: 123-131
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca^<2+> signalling in rodent NG108-15 neuro blastoma cells2007
- Author(s)
  Higashida, H., Bowden, S. E. H., Yokoyama, S. Salmina, A., Hashii, M., Hoshi, N., Zhang, J.-S., Knyjnik, R., Noda, M., Zhong, Z. G., Jin, D., Higashida, K., Takeda, H., Akita, T., Kuba, K., Yamagishi, S., Shimizu, N. Takasawa, S., Okamoto, H. and Robbins, J.
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- NAID
  10024413034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590211
[Journal Article] Bidirectional Ca^<2+>-coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca^<2+> entries in rat brown adipocytes.2007
- Author(s)
  Kuba, M., Higure, Y., Susaki, H., Hayato, R. Kuba, K.
- Journal Title
  
  Amer. J. Physiol. 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Bile acid enhyances sympathetic signaling Processes in brown adipocytes and prevents obesity formation under high-fat diet2009
- Author(s)
  Hiroki Nagai, Ryotaro Hayato, Masako Kuba, Yoko Higure, Kenji Kuba
- Organizer
  The 36^<th> Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20590221
[Presentation] Interaction of alpha-and be-ta-actions on intracellular calcium dynamics of mouse brown adipocytes.2009
- Author(s)
  Ryotaro Hayato, Yoko Higure, Masako Kuba, Kenji Kuba
- Organizer
  The 36^<th> Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20590221
[Presentation] Ca^<2+> entry activated by β-adrenergic mitochondrial uncoupling in brown adipocytes.2009
- Author(s)
  Ryotaro Hayato, Yoko Higure, Masako Kuba, Hiroki Nagai, Kenji Kuba
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20590221
[Presentation] Bidirectional Ca^<2+> coupling between endoplasmic reticulum,mito-chondria and multimodal regulation of plasmalemmal Ca^<2+> entry in rat brown adipocytes2008
- Author(s)
  Hayato, R., Higure, Y., Kuba, M. and Kuba, K.
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京都
- Year and Date
  2008-03-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Effects of high fat diet and cholic acids on adrenergic Ca^<2+> signaling and thermogenesis in brown adipocytes2008
- Author(s)
  R. Hayato, Y. Higure, M. Kuba and K. Kuba
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Bile acid intake enhances noradrenaline-induced Ca^<2+> signaling and thermogenesis in brown adipocytes of high fat-fed mice2007
- Author(s)
  Hayato, R., Higure, Y., Kuba, M. and Kuba, K.
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪市
- Year and Date
  2007-03-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Sequential activation of Ca^<2+> release at mitochondria and ER and plasmalemmal Ca^<2+> entry by the β-action of noradrenaline in rat brown adipocytes2007
- Author(s)
  Higure, Y., Hayato, R., Kuba, M. and Kuba, K.
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪市
- Year and Date
  2007-03-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] acid intake enhances noradrenaline-induced Ca^<2+> signaling and thermogenesis in brown adipocytes of high fat-fed mice.2007
- Author(s)
  Hayato, R., Higure, Y., Kuba, M., Kuba, K. Bile
- Organizer
  The Proceedings of the 84th Annual Meeting.
- Place of Presentation
  Osaka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Sequential activation of Ca^<2+> release at mitochondria and ER and plasrnalemmal Ca^<2+> entry by the β-action of noradrenaline in rat brown adipocytes.2007
- Author(s)
  Higure, Y., Hayato, R., Kuba, M., Kuba, K.
- Organizer
  The Proceedings of the 84th Annual Meeting.
- Place of Presentation
  Osaka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Bidirectional Ca^<2+> coupling between endoplasmic reticulum, Mitochon dria and multimodal regulation of plasmalemmal Ca^<2+> entry in rat brown adi pocytes.2007
- Author(s)
  Hayato, R., Higure, Y., Kuba, M., Kuba, K.
- Organizer
  The Proceedings of the 85th Annual Meeting.
- Place of Presentation
  Tokyo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Functional Ca^<2+> coupling between the endoplasmic reticulum,mitochondria and the plasma membrane in rat brown adipocytes2006
- Author(s)
  Hayato, R., Higure, Y., Kuba, M. and Kuba, K.
- Organizer
  The 63th Congress of the Federation of Asian and Oceanin Physiological Societies
- Place of Presentation
  韓国、ソウル
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Activation of multimodal plasmalemmal Ca^<2+> entries via mitochondrial uncoupling by the β-action of noradrenaline in rat brown adipocytes2006
- Author(s)
  Higure, Y., Hayato, R., Kuba, M. and Kuba, K.
- Organizer
  The 63th Congress of the Federation of Asian and Oceanin Physiological Societies
- Place of Presentation
  韓国、ソウル
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Activation of multimodal plasmalemmal Ca^<2+> entries via mitochondrial uncoupling by the β-action of noradrenaline in rat brown adipocytes.2006
- Author(s)
  Higure, Y., Hayato, R., Kuba, M., Kuba, K.
- Organizer
  The 63th Congress of the Federation of Asian and Oceanin Physiological Societies.
- Place of Presentation
  Seoul, Korea
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211
[Presentation] Functional Ca^<2+> coupling between the endoplasmic reticulum, mitochondria and the plasma membrane in rat brown adipocytes.2006
- Author(s)
  Hayato, R., Higure, Y., Kuba, M., Kuba, K.
- Organizer
  The 63th Congress of the Federation of Asian and Oceanin Physiological Societies.
- Place of Presentation
  Seoul, Korea
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590211

1. AKAIKE Norio (30040182)

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KUBA Kenji 久場 健司

Research Projects

Research Products

Co-Researchers

褐色脂肪細胞のアドレナリン受容体シグナリングの肥満発症と予防における役割Principal Investigator

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Bimodal Regulation of Plasmalemmal Ca2+ entry by the coupling of mitochondria and the endoplasmic reticulumPrincipal Investigator

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シナプス前終末の可塑的な細胞内Ca^<2+>遊離機構と伝達物質放出Principal Investigator

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Development of a total fluorescence collecting-two photon laser scanning microscope and analysis of intracellular Ca^<2+> dynamicsPrincipal Investigator

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A Study on intra uPrincipal Investigator

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Physiological studies on the mechanisms of synaptic transmission.Principal Investigator

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The development of a two photon laser-scanning confocal microscope and its application to intracellular Ca^<2+> measurementPrincipal Investigator

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異種のタタシナプス入力に対する海馬ニューロンの応答様式Principal Investigator

Principal Investigator

KUBA Kenji 久場健司