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TSUCHIDA Nobuo  土田 信夫

ORCIDConnect your ORCID iD *help
… Alternative Names

上田 信夫  ウエダ ノブオ

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Researcher Number 60089951
External Links
Affiliation (based on the past Project Information) *help 2000 – 2005: Graduate School, Tokyo Medical and Dental University, Molecular Cellular Oncology and Microbiology Professor, 大学院・医歯学総合研究科, 教授
1999: 東京医科歯科大学, 医学部, 教授
1986 – 1999: 東京医科歯科大学, 歯学部, 教授
1996: 東京医科歯科大学, 歯学部, 教師
1995: 東京医科歯科大学, 医学部, 教授 … More
1993 – 1994: 東京医科歯科大, 歯, 教授
1993: 東京医科歯科大学, 医学部, 教授
1992: 東京医歯大, 歯学部, 教授
1990 – 1991: 東京医科歯科大学, 歯学部, 文部教官教授
1987 – 1990: 東京医科歯科大学, 歯学部・口腔細菌, 教授
1989: Tokyo Med. & Dent. University, Dept. of Microbiology, Professor, 歯学部口腔細菌, 教授
1989: 東京医科歯科大学, 歯学部口腔細菌学教室, 教授
1987: 東京医科歯科大学, 歯学部・口腔細菌学教室, 教授
1986: 東京医科歯科大, 歯・口腔細菌学, 教授
1986: 東京医科歯科大学, 歯科部, 教授 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Functional basic dentistry / Morphological basic dentistry / Gastroenterology / 病態科学系歯学(含放射線系歯学)
Except Principal Investigator
Functional basic dentistry / 外科・放射線系歯学 / Periodontal dentistry / Surgical dentistry / Morphological basic dentistry … More / 病態科学系歯学(含放射線系歯学) / Cell biology / Gastroenterology / Circulatory organs internal medicine Less
Keywords
Principal Investigator
p53 / 口腔癌 / 癌抑制遺伝子 / ERK / Naf1 / SSCP / PCR / 口腔扁平上皮癌 / EGFR / CGH … More / H-ras / oral cancer / リン酸化 / ras / 扁平上皮癌 / アポトーシス / 温度感受性変異株 / 変異 / binding protein / SNT-2 / two hybrid / mutation / AKT / シグナル伝達 / NAF1 / two hybrid system / N-ras / temperature sensitive / transformation / HSP70 / M / G2 / HPV / 骨肉腫 / p53遺伝子 / ras遺伝子 / G1停止 / alkalinephosphatase / osteosarcoma / cDNAクローン / 分化誘導 / ハイドロキシアパタイト / グラ蛋白質 / オステオネクチン / アルカリフォスファターゼ / 分化 / アルカリホスファターゼ / drosophila melanogaster / GST-fusion protein / MKP-1 / CDドメイン / Mutation / ショウジョウバエ / GST融合蛋白質 / 結合蛋白質 / SNT2 / signal trransduction / microarra / 生存シグナル / 増殖シグナル / EGG / Snt2 / microarray / amplification / 酵母 / マップキナーゼ / MEK阻害剤 / NEF / 増幅 / eradication / H. pylori / oral squamous cell carinomas / adrenocortical tumors / tumors in digestive tract / cancer-related genes / 除菌療法 / 除菌 / H.pylori / 副腎腫瘍 / 消化器腫瘍 / 癌関連遺伝子 / transrepresson / p130 / 転写活性 / トランスフォーメーション抑制能 / ゲルシフトアッセイ / differantial display / transrepression / ras gene / p53 gene / squamous cell carcionoma / タバコ / Oral cancer / Squamous cell carcinoma / Tumor suppressor gene / P53 / Immunohistochemistry / 抗p53抗体 / 免疫組織化学 / SSCP (single strand confomation polymorphysm) / PCR (polymerase chain reaction) / p53 Gene / Ras Gene / Tumor Suppressor Gene / Oncogene / Squamous Cell Carcinoma / Polymerase chain Reaction(PeR) / 癌抑性遺伝子 / Polymerase Chain Reaction(PCR) / 病理切片 / SSCP(single strand confomation polymarphysm) / PCR(polymerase chain reaction) / 癌遺伝子 / 協同作用 / DNA腫瘍ウイルス / レトロウイルス / 発癌遺伝子 / トランスフォーミング遺伝子 / 不死化遺伝子 / ネクローシス / 歯周 / Actinobacillus actinomycetemcomitans / Bacteroides forsythus / 歯周病原性細菌 / 細胞死誘導因子 / G2チェックポイント / 細胞周期 / CDT / 細菌毒素 / Bacteroides forthysus / Actinobacillus actinomycetemcomtans / 歯周病 / テトラサイクリンプロモーター / HBV / 熱ショック / Rb / トランスホーメーション / トランスアクチベーション … More
Except Principal Investigator
p53 / G2 arrest / cell cycle / apoptosis / 細胞周期 / アデノウイルス / アポトーシス / RB蛋白質 / 口腔癌 / RB / がん遺伝子 / がん抑制遺伝子 / レトロウイルスLTR / EBウイルス / パピローマウイルス / B型肝炎ウイルス / ヒトがんウイルス・エンハンサー / c-myc / p21 / Bacteroides oralis / Tannerella forsythensis / Bacterial pathogen / periodontitis / periodontopathic bacteria / cytocidal toxin / Actinobacillus actinomycetemcomitans / 殺細胞因子 / CDT(cytolethal distending toxin) / 歯周炎 / Bacteroides forsythus / 歯周病原性細菌 / interaction / transcription / E1A / Adenovirus / Id / CGH / Comparative Genomic Hybridization(CGH) / p53癌抑制遺伝子 / in situ hybridization / 癌 / mgl-1 / Cdkインヒビター / Cdk4 / サイクリンD / 癌抑制遺伝子 / アデノウイルスE1A / 増殖因子 / 腫瘍侵潤 / 血管新生抑制 / 骨吸収 / 無蛋白培地 / 扁平上皮癌 / パピロ-マウイルス / トランスフォ-メ-ション / トランスフォ-ム遺伝子 / c-H-ras-1 / transcriptional controlling element / Rb gene / Human Oral Cancer / 遺伝子導入 / myc / 活性化ras / RB遺伝子 / 癌遺伝子 / ヒトロ腔癌 / 活性化c-H-ras-I / 転写調節領域 / Rb遺伝子 / ヒト口腔癌 / dextranase / pGL1 / Bacteroides oralis Ig4a / クローニング / デキストラナーゼ / CDT (cytolethal distending toxin). / Tannerellaforsythensis / cytocidal toxin (CCT) / 細胞死誘導因子(殺細胞因子:CCT) / Tonnerella forsythensis / 臨床検査 / モノクロナール抗体 / 細胞致死因子(CCT) / 細胞死 / monoclonad antibody / cytopathy / Cell death / cytolethal istending loxin(CDT) / cytocidal toxin(CCT) / Actinobacillus actinomyctemcomitans / Tannerella forstyensis / 精製 / 組換え蛋白質 / ORF / 遺伝子 / 病原因子 / 歯周病 / ELISA / monoclonal antibody / Cytocidal toxin / Cytolethal distending toxin(Cdt) / cellular toxicity / モノクローナル抗体 / 細胞障害 / Cytolethal distending toxin / Tannerella forsyhensis / CDT (cytolethal distending toxin) / ネクローシス / 細胞死誘導因子 / 細胞死誘導因子(殺細胞因子) / DNA複製 / HLH蛋白 / gene / chromosome / adrenocortical tumor / gastric carcinoma / DNA copy number / 癌関連遺伝子 / Lymph Node Metastasis / Tumor Malignancy / DNA Copy Number / Chromosome / Oral (Squamous Cell) Carcinoma / Hybridization (CGH) / Comparative Genomic / Comparative Genomic Hybridization (CGH) / リンパ節転移 / 癌悪性度 / DNAコピー数 / 染色体 / 口腔(扁平上皮)癌 / molecular diagnosis / temperature sensitive mutant / p53 tumor suppressor gene / PKC eta / vascular endoepitheraial protein / cell line establishment / normal human keratinocytes from oral mucosa / oral squamous cell carcinoma / サイトカイン / cell line. / cytocaine / cell line / Squamous cell carcinoma / 血管内皮細胞増殖抑制因子 / リンパ球増殖抑制因子 / 血管内皮細胞増子直抑制因子 / リンパ球増子直抑制因子 / 生理活性物質 / 悪性度評価法 / Neuron associated bone / Epitheliomesenchymal interaction / differentiation factor / Growth / Homeobox gene / Positional information / Morphogen / Limb bud / Morphogenesis / 共唯点レ-ザ-顕微鏡 / レチノイン酸レセプタ- / レチノイン酸 / 共焦点レ-ザ-顕微鏡 / ペプチド成長因子 / 骨誘導因子 / 位置価 / 共焦点レーザー顕微鏡 / 骨形成 / 神経投射組織 / 上皮間充織相互作用 / 成長分化因子 / ホメオボックス遺伝子 / 位置情報 / モルフォジェン / 肢芽 / 形態形成 / エンハンサー結合タンパク質 / エンハンサー素領域 / がん遺伝子c-myc / ハピローマウイルス / がん遺伝子cーmyc / 白血病ウイルス / ポリオーマウイルス / oncogene / 顔面形態形成 / ヒト癌遺伝子 / DNAトランスフェクション / トランスホーメーション共同作用 / E1B遺伝子 / E1A遺伝子 / MMTV-LTR / MMTVの定量法 / 乳癌前癌病変 / 乳癌抑制遺伝子 / MMTVゲノム / MMTV / 妊娠依存性乳癌 / ヒト乳癌抗原 / ヒト乳癌 / マウス乳癌 / ラット乳癌 / スンクス乳癌 / 乳癌ウイルス / E2F / ストレス / UbcH5 / Mdm2 / Ca^<++>依存型 / ユビキチン / ヒトパピローマウィルス / Tax / HTLV-I / RBQ-3 / HPVE7 / IRF / p300 / トランスフォーメション / トランスフォーム遺伝子 / 遺伝子クロ-ニング / Teratocarcinoma / cDNAライブラリ- / 不死化癌遺伝子 / cーmyc / ウイルスハンサ- / ウイルスLTR / 転写開始点 / トランスホ-メ-ション / ヒト活性化型cーHーrasー1(EJ6.6) / 腫瘍浸潤 / P53癌抑制遺伝子 / 血管内皮 / 血管平滑筋 / 細胞増殖抑制 / 血管新生 / インタ-フェロン / リンパ球 / マクロファ-ジ / 動脈硬化 / デルタ・クリスタリン遺伝子 / cーmyc遺伝子 / エンハンサー結合タンパク因子 Less
  • Research Projects

    (42 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (71 People)
  •  Abnormalities of structure, function, expression, and signal transduction of ERK in relation to carcinogenesisPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Aberrant cell growth signaling in oral cancerPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Analyses for the cytopathic mechanism of cytocidal toxin from periodontpathic bacteria

    • Principal Investigator
      NAKAJIMA Takuma
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical and Dental University
  •  Isolation of the Cytocidal toxin (CCT) from periodontopathic bacteria and antibody preparation against CCT: with a view to clinical application.

    • Principal Investigator
      ARAKAWA Shinichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  歯周病原性細菌の保有するアポトーシス様細胞死誘導因子の単離・同定Principal Investigator

    • Principal Investigator
      土田 信夫
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical and Dental University
  •  Alterations of ERK gene and the signal transduction pathway in oral squamous cell carcinoma and the roles in the genesis of the cancerPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of cell death inducing factors from periodontopathic bacteria.

    • Principal Investigator
      ARAKAWA Shinichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Tokyo Medical and DentaJ University
  •  非ストレス負荷ヒト癌細胞におけるCa^<++>依存性ユビキチン化を介する野生型p53の分解とその抑制機構

    • Principal Investigator
      NAKAJIMA Takuma
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokyo Medical and Dental University
  •  The function of human HLH-type inhibitor of differentiation, Id-1H and Id-2H that induce abrogation of G1 maturation in mutant p53 expressing cells.

    • Principal Investigator
      NAKAJIMA Takuma
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Graduate School, Tokyo Medical and Dental University
  •  Genetic alterations in cancers of digestive tract as analyzed by CGH, in relation to genesis of cancer and the metastasis.Principal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  p53癌抑制遺伝子によるヒト発がん抑制の分子機構Principal Investigator

    • Principal Investigator
      土田 信夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular mechanisms of genesis of oral squamous cell carcinomaPrincipal Investigator

    • Principal Investigator
      TSUCHIDA N.
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  DNA Copy Number Changes in Gastroenteric Tumors detected by Comparative Genomic Hybridization.

    • Principal Investigator
      TOMINAGA Shizuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yokohama City University
  •  癌抑制遺伝子産物の生理機能

    • Principal Investigator
      田矢 洋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  温度感受性ヒトp53癌抑制遺伝子を用いた細胞増殖制御機構の解明Principal Investigator

    • Principal Investigator
      土田 信夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  Detection of Oncogenes Affecting Genetic Diagnosis and Prognosis in the Patients with Oral Cancer by CGH

    • Principal Investigator
      AMAGASA Teruo
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  癌抑制遺伝子産物の生理機能

    • Principal Investigator
      田矢 洋一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Roles of p53 and ras gene mutations in genesis of oral SCC in IndiaPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tokyo Medical and Dental University
  •  癌抑制遺伝子産物の生理機能

    • Principal Investigator
      田矢 洋一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  「口腔扁平上皮癌で見いだされた変異型p53癌抑制遺伝子の細胞癌化における役割」Principal Investigator

    • Principal Investigator
      土田 信夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒトT細胞白血病ウイルスによる癌化機構の分子生物学的解析

    • Principal Investigator
      大和 建嗣
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Establishment of A Novel System for Malignancy Grading of Oral Cancer Using Molecular Biological Technique

    • Principal Investigator
      ENOMOTO Shoji
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Faculty of Dentistry, Tokyo Medical and Dental University
  •  がん遺伝子とがん抑制遺伝子の相互作用による発がんの分子機構

    • Principal Investigator
      藤永 慧
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  がん遺転子とがん抑制遺伝子の相互作用による発がんの分子機構

    • Principal Investigator
      藤永 けい
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Molecular diagnosis of oral cancer based on aberrant expression and structural alterations of the p53 tumor suppressor genePrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  がん遺伝子とがん抑制遺伝子の相互作用による発がんの分子機構

    • Principal Investigator
      藤永 〓
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  口腔癌の新しい診断ならびに治療法に関する分子細胞生物学的研究

    • Principal Investigator
      ENOMOTO Shoji
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Tokyo Medical and Dental University
  •  cーHーrasー1癌遺伝子の発現機構の解析

    • Principal Investigator
      SHIOIRI Shigeaki
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Tokyo Medical and Dental University
  •  未知の細胞不死化に関与する遺伝子のクロ-ニング

    • Principal Investigator
      IKEDA Masaaki
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Three-dimensional molecular status of bone morphogenesis as revealed from molecular biological analyzes.

    • Principal Investigator
      TANIGUCHI Shigehiko, 榎本 昭二
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Okayama University
      Tokyo Medical and Dental University
  •  がんウイルス・エンハンサーの機能

    • Principal Investigator
      小池 克郎
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  動脈硬化巣における毛細血管新生破綻のメカニズムに関する研究

    • Principal Investigator
      下門 顕太郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of oncogenes and tumor-suppressor genes in oral cancers and the application to diagnosisPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Faculaty of Dentistry, Tokyo Medical & Dental University
  •  Immunological and Molecular Biological Study on Oncogenes In Human Oral Cancer.

    • Principal Investigator
      SHIOIRI Shigeaki
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Tokyo Medical & Dental University
  •  がんウイルス・エンハンサーの機能

    • Principal Investigator
      小池 克郎
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発癌遺伝子の共同作用による細胞のがん化Principal Investigator

    • Principal Investigator
      土田 信夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  がんウイルス・エンハンサーの機能

    • Principal Investigator
      小池 克郎
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  In vitro differentiation of human osteosarcoma cellsPrincipal Investigator

    • Principal Investigator
      TSUCHIDA Nobuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Faculty of Dentistry, Tokyo Medical and Dental University
  •  Analysis of a glucanase gene from Bacteriodes oralis Ig4a

    • Principal Investigator
      TAKAHASHI Nobuyoshi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Faculty of Dentistry, Tokyo Medical and Dental University
  •  マウス乳癌ウイルス(MMTV)を中心とする各種動物の乳癌発生機構の比較解析

    • Principal Investigator
      星野 宗光
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  哺乳類胎仔の顔面形態形成におけるoncogeneの発現(in situ hybridization法による解析)

    • Principal Investigator
      江藤 一洋
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  ウイルス癌遺伝子導入細胞を用いたヒト癌遺伝子の単離とヒトにおける発癌機構の解析

    • Principal Investigator
      藤永 けい
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Sapporo Medical University

All 2006 2005 2004 Other

All Journal Article

  • [Journal Article] Role of caspase 8 as a determinant in chemosensitivity of p53+mutated head and neck squamous cell carcinoma cell lines2006

    • Author(s)
      Kaneda Y, Shimamoto H, Matsumura K, Arvind R, Zhang S, Sakai E, Omura K, Tsuchida N
    • Journal Title

      Journal of Medical and Dental Sciences 53

      Pages: 53-66

    • NAID

      110004226769

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Unique role of - SNT-2/FRS2β/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways2006

    • Author(s)
      Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Tsuchida N
    • Journal Title

      Oncogene E-pub (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Methylation of E-cadherin and hMLH1 hrnrd in Indian sporadic breast carcinomas2006

    • Author(s)
      Viswanathan M, Solomon SPR Tsuchida N Selvam GS, Shanmugam G
    • Journal Title

      Indian Journal of Experimental Biology 44

      Pages: 115-119

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Methylation of E-cadherin and hMLH1 hrnrd in Indian sporadic breast carcinomas2006

    • Author(s)
      ViswanathanM, Solomon SPR, Tsuchida N, Selvam GS, Shanmugam G
    • Journal Title

      Indian Journal of Experimental Biology 44

      Pages: 115-119

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Methylation of E-cadherin and hMLH1 hrnrd in Indian sporadic breast carcinomas2006

    • Author(s)
      Viswanathan M, Solomon SPR, Tsuchida N, Selvam GS, Shanmugam G
    • Journal Title

      Indian Journal of Experimental Biology 44

      Pages: 115-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Role of caspase 8 as a determinant in chemosensitivity of p53-mutate d head and neck squamous cell carcinoma cell lines2006

    • Author(s)
      Kaneda Y, Shimamoto H, Matsumura K, Arvind R, Zhang S, Sakai E, Omura K, Tsuchida N
    • Journal Title

      J.Medical and Dental Sciences 53

      Pages: 53-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Role of caspase 8 as a determinant in chemosensitivity of p53+mutated head and neck squamous cell carcinoma cell lines2006

    • Author(s)
      Kaneda Y, Shimamoto H, Matsumura K, Arvind R, Zhang S, Sakai E, Omura K, Tsuchida N
    • Journal Title

      Journal of Medical and Dental Sciences 53(3月発行予定)

    • NAID

      110004226769

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] 変異型p53口腔扁平上皮癌細胞株の化学療法剤感受性におけるcaspase-8の役割2005

    • Author(s)
      金田善正, R Arvind, 島本裕彰, 小村健, 土田信夫
    • Journal Title

      Journal of Oral Biosciences 47(補)

      Pages: 96-96

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] A mutation in the common docking domain of ERK2 in a human cancer cell line, which associated with its constitutive phosphorylation2005

    • Author(s)
      Arvind R, Shimamoto A, Momose F, Amagasa T, Omura K, Tsuchida N
    • Journal Title

      International Journal of Oncology 27

      Pages: 1499-1504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] EGF誘導した細胞のトランスフォーメーションを抑制するRS2 Beta/SNT+2の役割2005

    • Author(s)
      黄琳, 渡辺誠, 渋谷正史, 後藤典子, 土田信夫
    • Journal Title

      Sixty-fourth annual meeting of the Japanese cancer association

      Pages: 374-374

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] A mutation in the common docking domain of ERK2 in a human cancer cell line, which associated iwth its constitutive phophsrylation2005

    • Author(s)
      Arvind R, Shimamoto A, Momose F, Amagasa T, Omura K, Tsuchida
    • Journal Title

      International Journal of Oncology 27

      Pages: 1499-1504

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] A mutation in the common docking domain of ERK2 in a human cancer cell line, which associated iwth its constitutive phophsrylation2005

    • Author(s)
      Arvind R, Shimamoto A, Momose F, Amagasa T, Omura K, Tsuchida N
    • Journal Title

      International Journal of Oncology 27

      Pages: 1499-1504

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal diseashe2004

    • Author(s)
      Hasebe A, Yoshimura A, Into T, Kataoka H, Tanaka S, Arakawa S, Ishikura H, Golenbock DT, Sugaya T, Tsuchida N, Kawanami M, ara Y, Shibata K.
    • Journal Title

      Infection and Immunity 72・3

      Pages: 1318-1325

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] 口腔扁平上皮癌細胞株におぇるリン酸化Akt蛋白質発現と抗癌剤2004

    • Author(s)
      金田善正, Ramanathan Arvind, 島本裕彰, 小村健, 土田信夫
    • Journal Title

      J.Oral Biosciences 46・5

      Pages: 397-397

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.2004

    • Author(s)
      Huang L, Gotoh N, Zhang S, Shibuya M, Yamamoto T, Tsuchida N.
    • Journal Title

      Biocheical Biophyscal Research Communication 324・3

      Pages: 1011-1017

    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation2004

    • Author(s)
      Huang L, Gotoh N, Zhang SL, Shibuya M, Yamamoto T, Tsuchida N
    • Journal Title

      Biochemical & Biological Research Communication 324

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation2004

    • Author(s)
      Hunng L, Gotoh N, Zhang SL, Shibuya M, Yamamoto T, Tsuchida N
    • Journal Title

      Biochemical & Biological Research Communication 324

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
  • [Journal Article] Unique role of SNT-2/FRS2β/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways

    • Author(s)
      Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Tsuchida N
    • Journal Title

      Oncogene (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390520
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