YAMADA Yuichiro 山田祐一郎

… Alternative Names

山田祐一郎ヤマダユウイチロウ

YAMAMOTO Yuichiro 山本祐一郎

山田裕一郎ヤマダユウイチロウ

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Researcher Number	60283610
Other IDs
External Links
Affiliation (Current)	2025: 株式会社関西メディカルネット(関西電力医学研究所), 糖尿病研究センター, センター長
Affiliation (based on the past Project Information) *help	2020: 株式会社関西メディカルネット(関西電力医学研究所), 糖尿病研究センター, センター長 2018 – 2019: 秋田大学, 医学系研究科, 教授 2011 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授 2013: 秋田大学, 大学院医学系研究科, 教授 2009 – 2012: Akita University, 大学院・医学系研究科, 教授 … More 2006 – 2008: 秋田大学, 医学部, 教授 2005: Kyoto University, Graduate School of Medicine, Associate Professor, 大学院・医学研究科, 助教授 2005: 京都大学, 大学院医学研究科, 助教授 1998 – 2005: 京都大学, 医学研究科, 助教授 1998 – 1999: 京都大学, 大学院・医学研究科, 助教授 1997: 京都大学, 大学院・医学研究科, 助手 1996 – 1997: Graduate School of Medicine, Kyoto Univ., 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Eating habits, studies on eating habits / Metabolomics / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Endocrinology / Obstetrics and gynecology Except Principal Investigator Kidney internal medicine / General surgery / Metabolomics / Hygiene / 内分泌・代謝学 / Metabolomics
Keywords	Principal Investigator インクレチン / GIP / 糖尿病 / GLP-1 / obesity / diabetes / incretin / 肥満 / SNP / 遺伝子欠損マウス … More / 栄養学 / 糖代謝 / 病態栄養学 / 消化管ホルモン / 老化 / 生活習慣病 / 加齢 / energy expenditure / エネルギー代謝 / osteoporosis / knockout mouse / Incretin / 骨粗鬆症 / Knockout mice / 骨代謝 / 脂肪細胞 / 不妊 / 生理活性 / αグルコシダーゼ / 食品 / シグナル伝達 / 分子遺伝学 / 節約遺伝子 … More Except Principal Investigator GIP / 糖尿病性腎症 / LPI / 糖尿病 / インクレチン / GLP-1 / GLUT2 / Tet expression system / マススクリーニング / 創始者変異 / 遺伝性疾患 / 遺伝疫学 / SLC7A7 / Osler-Rendu-Weber / ノックアウトマウス / インスリン分泌 / ATF2 / PKA / cAMP / CREM / PCR-SSCP / GIP受容体 / 膵β細胞 / 1型糖尿病 / 生体ドナー / 生体膵島移植 / 内科 / regenerative medicine / pancreatectoy / pancreatic regeneration / beta-cell / bio-artificial pancreas / therapy for diabetes mellitus / stem cell / 血管新生 / バイオ人工膵臓 / 分化誘導 / 再生医療 / 膵切除 / 膵再生 / β細胞 / バイオ人工膵 / 糖尿病治療 / 幹細胞 / Type 1 diabetes / GMP facility / Non-heart-beating donor / Islet isolation method / Living donor / Living donor islet transplantation / 二層法膵保存 / 膵管保護 / ブタ膵島 / ISO9001 / GMP / 膵島移植 / インスリン依存状態糖尿病 / 膵島分離技術 / 生体膵島移埴 / GMP施設 / 心臓死ドナー / 膵島移植分離技術 / osteoblast / adipocyte / pancreatic beta cells / incretin / 骨芽細胞 / 脂肪細胞 / insulin secretion / circadian clock / CRY2 / CRY1 / BMAL-1 / CLOCK / インスリン / 膵内分泌 / 時計遺伝子 / 生体時計 / proteomics / isolation / recessive / bottle neck / genetic drifts / nonrandom mating / diseases genetic / epidemiological genetic / 家族性甲状腺腫 / 早期診断 / Osler-Rendu-Weber病 / 嚢胞性腎症 / 構造異常 / 地理的隔離 / 社会的隔離 / 集団的遺伝学 / プロテオミックス / 隔離 / 劣性 / ボトルネック現象 / 遺伝的ドリフト / 雑交配 / 遺伝病 / Proliferation and differentiation / Target gene / Transcription factor / SAGE / pancreatic β-cell line / Tet Expression System / 膵β細胞の発生と機能 / 膵Β細胞株 / 分化・増殖 / 標的遺伝子 / 転写因子 / SAGE法 / 膵β細胞株 / proinsulin / polycystic / R410X / transporters / mutations / 加齢 / Hartnup / 心肥大 / OCTN2 / トランスポーター / ベータ細胞 / Osler-Rendu-wever / プロインスリン / 多のう胞 / P410X / SL7A7 / 輸送蛋白 / 突然変異 / Diabetes mellitus / High fat diet / Insulin resistance / Insulin secretion / GIP modulation / GIP receptor deficient mice / ジーンターゲティング / GIPシグナル伝達 / 高脂肪食負荷 / インスリン抵抗性 / GIP受容体欠損マウス / CaMK TV / glucose-responsive / insulin gene / CRE-BPl / calmodulin-dependent protein kinase IV / カルシウムチャネル / TBP / p300 / CBP / CRE-BP1 / CRE / CaMKIV / グルコース応答性 / インスリン遺伝子 / GIP Receptor / Voltage-dependent Calcium Channel / Glucose Transporter / Pancreatic beta cell / Mutation / Gene / Diabetes Mellitus / 転写調節 / PCR-SSCP法 / 電位依存性カルシウム・チャネル / 糖輸送担体 / 変異 / 遺伝子 / ケモカイン / マイクロRNA / 酸化ストレス / アポトーシス / c-JunNH(2)-terminal kinase / マウスモデル / 免疫抑制剤 / 腹腔鏡手術 Less

Development of diet therapy aiming at extending healthy life expectancy based on GIP signal suppressionPrincipal Investigator
- Principal Investigator
  
  Yamada Yuichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  株式会社関西メディカルネット(関西電力医学研究所)
  Akita University
The role of GIP in the pathogenesis of diabetic nephropathy and its renal protective effects
- Principal Investigator
  
  FUJITA HIROKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
The role of GLP-1/DPP-4 signaling in diabetic nephropathy and its therapeutic potential
- Principal Investigator
  
  FUJITA HIROKI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
Binding of sperm and oocyte induced by gut factor: Novel strategy for treatment of male infertilityPrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Akita University
Identification of microRNAs involved in the development of diabetic nephropathy
- Principal Investigator
  
  FUJITA HIROKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
Research on the association of GIP and metabolic diseasesPrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Akita University
機能性食品による消化管因子分泌調節機構に関する研究Principal Investigator
- Principal Investigator
  
  山田祐一郎
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Akita University
Role of SOD in the pathogenesis of diabetic nephropathy
- Principal Investigator
  
  FUJITA Hiroki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
Study on insulinoropic mechanisms co-operated by GLP-1 and GIPPrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Akita University
生体ドナーからの膵島移植・再生医療によるインスリン依存状態糖尿病治療の確立
- Principal Investigator
  
  MATSUMOTO Shinichi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  General surgery
- Research Institution
  Fujita Health University
Studies on regenerative medicine for severe diabetes mellitus by stem cell biology
- Principal Investigator
  
  SUMI Shoichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Study on metabolism in vivo mediated by gut hormonePrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Kyoto University
Gut-peptides regulate metabolism in whole body.
- Principal Investigator
  
  HOSOKAWA Masaya, 清野裕
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Living donor islet transplantation for the treatment of sever diabetes
- Principal Investigator
  
  MATSUMOTO Shinichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
Analysis of the role of clock-associated-gene in regulating the fumction of pancreatic endocrine
- Principal Investigator
  
  HOSOKAWA Masaya, 黒瀬健
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
消化管シグナルのネットワークと糖尿病発症の解析Principal Investigator
- Principal Investigator
  
  山田祐一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Impact of mutations and polymorphisms in transporter families on population health
- Principal Investigator
  
  KOIZUMI Akio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KYOTO UNIVERSITY
Analysis of transcriptional network in pancreatic β-cells
- Principal Investigator
  
  SEINO Yutaka
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  KYOTO UNIVERSITY
Extended linkage disequilibrium mapping based on a founder effect attributable to historical and genetic isolation
- Principal Investigator
  
  KOIZUMI Akio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KYOTO UNIVERSITY
Roles of incretin -Analysis of incretin receptor-deficient micePrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  KYOTO UNIVERSITY
Study on a network of gut signals and development of diabetesPrincipal Investigator
- Principal Investigator
  
  YAMADA Yuichiro
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Characterizetion of glucose-induced signal transduction and its impairment in type 2 diabete
- Principal Investigator
  
  SEINO Yutaka
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyoto University
Generation and analysis of GIP Receptor deficient mice
- Principal Investigator
  
  YANO hideki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
A study on the beta-Cell glucose sensors in insulin secretion : The relationship between dysfunction of glucose sensors and development of diabetes mellitus
- Principal Investigator
  
  SEINO Yutaka
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY

All 2021 2020 2019 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 2001

All Journal Article Presentation Patent

[Journal Article] Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms2021
- Author(s)
  Kato Shunsuke、Sato Takehiro、Fujita Hiroki、Kawatani Masahiro、Yamada Yuichiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-88612-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03171
[Journal Article] GLP-1 Receptor Signaling Differentially Modifies the Outcomes of Sterile vs Viral Pulmonary Inflammation in Male Mice2020
- Author(s)
  Sato T, Shimizu T, Fujita H, Imai Y, Drucker DJ, Seino Y, Yamada Y
- Journal Title
  
  Endocrinology
  
  Volume: 161(12) Issue: 12
- DOI
  10.1210/endocr/bqaa201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-18H03171
[Journal Article] Inhibition of GIP signaling extends lifespan without caloric restriction2019
- Author(s)
  Hoizumi Manabu、Sato Takehiro、Shimizu Tatsunori、Kato Shunsuke、Tsukiyama Katsushi、Narita Takuma、Fujita Hiroki、Morii Tsukasa、Sassa Mariko Harada、Seino Yutaka、Yamada Yuichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 513 Issue: 4 Pages: 974-982
- DOI
  10.1016/j.bbrc.2019.04.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03171
[Journal Article] Magnitude of slowing gastric emptying by glucagon‐like peptide‐1 receptor agonists determines the amelioration of postprandial glucose excursion in Japanese patients with type?2 diabetes2019
- Author(s)
  Suganuma Yumi、Shimizu Tatsunori、Sato Takehiro、Morii Tsukasa、Fujita Hiroki、Harada Sassa Mariko、Yamada Yuichiro
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 11 Issue: 2 Pages: 389-399
- DOI
  10.1111/jdi.13115
- NAID
  120007169375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03171
[Journal Article] DPP-4 inhibition with alogliptin on top of anigiotensin II type 1 receptor blockage ameliorates albuminuria via up-regulation of SDF-1a in type 2 diabetic patients with incipient nephropathy2014
- Author(s)
  Fujita H, Taniai H, Murayama H, Ohshiro H, Sato S, Kikuchi N, Komatsu T, Komatsu Ko, Komatsu Ka, Narita T, Yamada Y
- Journal Title
  
  Endocr J
  
  Volume: 61 Pages: 159-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] Effects of miglitol, sitagliptin, and initial combination therapy with both on plasma incretins’ responses to a mixed meal and visceral fat in over-weight Japanese patients with type 2 diabetes. “The MASTER randomized, controlled trial”2014
- Author(s)
  Mikada A, Narita T, Yokoyama H, Yamashita R, Horikawa Y, Tsukiyama K, Yamada Y
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 106 Issue: 3 Pages: 538-547
- DOI
  10.1016/j.diabres.2014.09.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] The protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential2014
- Author(s)
  Fujita H, Morii T, Fujishima H, Sato T, Shimizu T, Hosoba M, Tsukiyama K, Narita T, Takahashi T, Drucker DJ, Seino Y, Yamada Y
- Journal Title
  
  Kidney Int
  
  Volume: 85 Issue: 3 Pages: 579-589
- DOI
  10.1038/ki.2013.427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals2014
- Author(s)
  Itoh K., Moriguchi R., Yamada Y., Fujita M., Yamato T., Oumi M., Holst JJ., Seino Y.
- Journal Title
  
  Nutrition Research
  
  Volume: 34 Issue: 8 Pages: 653-660
- DOI
  10.1016/j.nutres.2014.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501019, KAKENHI-PROJECT-25670692, KAKENHI-PROJECT-26460826
[Journal Article] Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor deficient mice.2014
- Author(s)
  Okawa T, Kamiya H, Himeno T, Kato J, Seino Yus, Fukami A, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Hayashi Y, Harada N, Yamada Y, Inagaki N, Seino Yut, Oiso Y, Nakamura J
- Journal Title
  
  J Diabetes Invest
  
  Volume: 5 Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] Effects of consumption of main and side dishes with white rice on postprandial glucose, insulin, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 responses in healthy Japanese men.2014
- Author(s)
  Kameyama N, Maruyama C, Matsui S, Araki R, Yamada Y, Maruyama T
- Journal Title
  
  Br J Nutr
  
  Volume: 111 Issue: 9 Pages: 1632-40
- DOI
  10.1017/s0007114513004194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes.2014
- Author(s)
  Omar BA, Liehua L, Yamada Y, Seino Y, Marchetti P, Ahrén B
- Journal Title
  
  Diabetologia
  
  Volume: 57 Issue: 9 Pages: 1876-1883
- DOI
  10.1007/s00125-014-3299-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] Quantitative Analytical Method for Determining the Levels of Gastric Inhibitory Polypeptides GIP and GIP in Human Plasma Using LC-MS/MS/MS2013
- Author(s)
  Miyachi A, Murase T, Yamada Y, Osonoi T, Harada KI
- Journal Title
  
  J Proteome Res
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] A quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS.2013
- Author(s)
  Miyachi A, Murase T, Yamada Y, Osonoi T, Harada KI
- Journal Title
  
  J Proteome Res
  
  Volume: 12 Issue: 6 Pages: 2690-99
- DOI
  10.1021/pr400069f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670692
[Journal Article] Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice2012
- Author(s)
  Fujita H, Fujishima H, Morii T, Sakamoto T, Komatsu K, Hosoba M, Narita T, Takahashi K, Takahashi T, Yamada Y
- Journal Title
  
  Hypertens Res
  
  Volume: 35(2) Pages: 213-220
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] Comparisons of the effects of 12-week administration of miglitol and voglibose on the responses of plasma incretins after a mixed meal in Japanese type 2 diabetic patients2012
- Author(s)
  Narita T, Yokoyama H, Yamashita R, Sato T, Hosoba M, Morii T, Fujita H, Tsukiyama K, Yamada Y
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 14(3) Pages: 283-287
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice2012
- Author(s)
  Fujita H, Fujishima H, Takahashi K, Sato T, Shimizu T, Morii T, Shimizu T, Shirasawa T, Qi Z, Breyer MD, Harris RC, Yamada Y, Takahashi T
- Journal Title
  
  Metabolism
  
  Volume: 61(12) Pages: 1714-1724
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] Efficacy and safety of patient-directed titration of once-daily pre-dinner premixed biphasic insulin aspart 70/30 injection in Japanese type 2 diabetic patients with oral antidiabetic drug failure: STEP-AKITA study2011
- Author(s)
  Narita T, Goto T, Suganuma Y, Hosoba M, Morii T, Sato T, Fujita H, Miura T, Shimotomai T, Yamada Y, Kakei M
- Journal Title
  
  J Diabetes Invest
  
  Volume: 2(1) Pages: 63-70
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy2011
- Author(s)
  Fujita H, Sakamoto T, Komatsu K, Fujishima H, Morii T, Narita T, Takahashi T, Yamada Y
- Journal Title
  
  Hypertens Res
  
  Volume: 34(12) Pages: 1302-1308
- NAID
  10030278001
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] Phenotypical variety of insulin resistance in a family with a novel mutation of the insulin receptor gene2010
- Author(s)
  Takahashi I, Yamada Y, Kadowaki H, Horikoshi M, Kadowaki T, Narita T, Tsuchida S, Noguchi A, Koizumi A, Takahashi T
- Journal Title
  
  Endocr J
  
  Volume: 57(6) Pages: 509-516
- NAID
  10029585142
- Data Source
  KAKENHI-PROJECT-22390183
[Journal Article] Reduction of renal superoxide dismutase in progressive diabetic nephropathy.2009
- Author(s)
  Hiroki Fujita, Hiromi Fujishima, Shinsuke Chida, Keiko Takahashi, Zhonghua Qi, Yukiko Kanetsuna, Matthew Breyer, Raymond Harris, Yuichiro Yamada, Takamune Takahashi
- Journal Title
  
  J Am Soc Nephrol 20
  
  Pages: 1303-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590943
[Journal Article] Miglitol induces prolonged and enhanced glucagon-like peptide-1 and reduced gastric inhibitory polypeptide responses after ingestion of a mixed meal in Japanese type 2 diabetic patients2009
- Author(s)
  Narita T, Katsuura Y, Sato T, Hosoba M, Fujita H, Morii T, Yamada Y
- Journal Title
  
  Diabet Med 26(2)
  
  Pages: 187-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Reduction of renal superoxide dismutase in progressive diabetic nephropathy2009
- Author(s)
  藤田浩樹, 山田祐一郎
- Journal Title
  
  Journal of the American Society of Nephrology 20
  
  Pages: 1303-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590943
[Journal Article] The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.2008
- Author(s)
  Chizumi Yamada
- Journal Title
  
  Endocrinology 149
  
  Pages: 574-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] A novel gastric inhibitory polypeptide (GIP) receptor splice variant influences GIP sensitivity of pancreatic β-cells in obese mice2008
- Author(s)
  Harada N, Yamada Y, Tsukiyama K, Yamada C, Nakamura Y, Mukai E, Hamasaki A, Liu X, Yamada K, Sasaki M, Toyoda K, Seino Y, Inagaki N
- Journal Title
  
  Am J Physiology Endocrinol Metab 294(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] The murine glucagon-like peptide-1 receptor is essential for control of bone resorption2008
- Author(s)
  Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, Tanaka K, Drucker DJ, Seino Y, Inagaki N
- Journal Title
  
  Endocrinology 149(2)
  
  Pages: 574-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice2008
- Author(s)
  Naitoh R, Miyawaki K, Harada N, Mizunoya W, Toyoda K, Fushiki T, Yamada Y, Seino Y, Inagaki N
- Journal Title
  
  Biochem Biophys Res Commun 376(1)
  
  Pages: 21-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Glycemic instability in type1 diabetic patients : Possible role of ketosis or ketoacidosis at onset of diabetes2008
- Author(s)
  Sassa M, Yamada Y, Hosokawa M, Fukuda K, Fujimoto S, Toyoda K, Tsukiyama K, Seino Y, Inagaki N
- Journal Title
  
  Diabetes Res Clin Pract 81(2)
  
  Pages: 190-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Insulin gene is a target in activin receptor-like kinase 7 signaling pathway in pancreatic beta-cells2008
- Author(s)
  Watanabe R, Shen ZP, Tsuda K, Yamada Y
- Journal Title
  
  Biochem Biophys Res Commun 377(3)
  
  Pages: 867-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes.2007
- Author(s)
  Chizumi Yamada
- Journal Title
  
  Biochem Biophys Res Commun 364
  
  Pages: 175-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes2007
- Author(s)
  Yamada C, Tsukiyama K, Yamada K, Yamane S, Harada N, Miyawaki K, Seino Y, Inagaki N, Yamada Y
- Journal Title
  
  Biochem Biophys Res Commun 364(1)
  
  Pages: 175-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Effect of selective cyclooxygenase-2 (COX-2) inhibitor treatment on glucose-stimulated insulin secretion in C57BL/6 mice2007
- Author(s)
  Fujita H, Kakei M, Fujishima H, Morii T, Yamada Y, Qi Z, Breyer MD
- Journal Title
  
  Biochem Biophys Res Commun 363(1)
  
  Pages: 37-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Effects of long-term pravastatin treatment on serum and urinary monocyte chemoattractant protein-1 levels and renal function in type 2 diabetic patients with normoalbuminuria2007
- Author(s)
  Fujita H, Koshimura J, Sato T, Miura T, Sasaki H, Morii T, Narita T, Kakei M, Ito S, Yamada Y
- Journal Title
  
  Ren Fail 29(7)
  
  Pages: 791-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] Clock Gene Defect Disrupts Light-Dependency of Autonomic Nerve Activity2007
- Author(s)
  Ikeda H, Yong Q, Kurose T, Todo T, Mizunoya W, Fushiki T, Seino Y, Yamada Y
- Journal Title
  
  Biochem Biophys Res Commun 364(3)
  
  Pages: 457-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591032
[Journal Article] SUIT, secreatory units of islets in transplantation : an index for therapeutic management of islet transplanted patients and its application to type 2 diabetes.2006
- Author(s)
  Yamada Y, Matsumoto S et al.
- Journal Title
  
  Diabetes Res Clin Pract 74
  
  Pages: 222-226
- Data Source
  KAKENHI-PROJECT-18109010
[Journal Article] Physiology of GIP--a lesson from GIP receptor knockout mice.2004
- Author(s)
  Yamada Y
- Journal Title
  
  Horm Metab Res 36(11-12)
  
  Pages: 771-774
- Data Source
  KAKENHI-PROJECT-13204042
[Journal Article] 心停止ドナーからの膵島移植によってインスリン離脱した1型糖尿病の1症例2004
- Author(s)
  山田祐一郎, 松本慎一ら
- Journal Title
  
  糖尿病 47
  
  Pages: 945-950
- NAID
  10014466439
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390376
[Journal Article] Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.2001
- Author(s)
  Yamada Y
- Journal Title
  
  Diabetes Metab Res Rev 17
  
  Pages: 213-216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13204042
[Journal Article] Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.2001
- Author(s)
  Yamada Y
- Journal Title
  
  Diabetes Metab ResRev 1 7
  
  Pages: 213-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204042
[Patent] インスリン抵抗性及び/又は肥満の予防剤もしくは改善剤2001
- Inventor(s)
  清野裕, 宮脇一真, 山田祐一郎, 坂信広, 鍔本義治, 武田基弘, 橋本洋幸, 山下篤行, 城森孝仁
- Industrial Property Rights Holder
  清野裕, 宮脇一真, 山田祐一郎, 坂信広, 鍔本義治, 武田基弘, 橋本洋幸, 山下篤行, 城森孝仁
- Industrial Property Number
  2001-144416
- Filing Date
  2001-05-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13204042
[Presentation] Rice cracker made from resistant starch-containing rice ameliorate post-prandial hyperglycemia2019
- Author(s)
  Kuwata H, Fujiwara Y, Yabe D, Watanabe T, Sasaki T, Higuchi Y, Saito Y, Arao H, Hirayama M, Goto H, Seino Y, Watanabe K, Yamada Y, Fujita N
- Organizer
  11th Scientific Meeting of the Asian Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03171
[Presentation] 177 精巣におけるGIPシグナルの低下は肥満・糖尿病における男性不妊をおこす2014
- Author(s)
  清水辰徳、月山克史、佐藤雄大、藤田浩樹、成田琢磨、寺田幸弘、山田祐一郎
- Organizer
  第87回日本内分泌学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25670692
[Presentation] Extrapancreatic effects of GIP and GLP-12013
- Author(s)
  Yamada Y
- Organizer
  Beta cell workshop 2013 Kyoto
- Place of Presentation
  京都市
- Invited
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] Extrapancreatic effects of GIP and GLP-1 Beta Cell Workshop 20132013
- Author(s)
  Yamada Y
- Organizer
  Kyoto
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] インクレチンの糖代謝2013
- Author(s)
  山田祐一郎
- Organizer
  第86回日本内分泌学会学術集会
- Place of Presentation
  仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] インクレチンの糖代謝2013
- Author(s)
  山田祐一郎
- Organizer
  第86回日本内分泌学会学術集会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] Mass spectrometry-based simultaneous quantification of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma2012
- Author(s)
  Yamada Y
- Organizer
  9th IDF-WPR congress
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] インクレチンの生理作用2011
- Author(s)
  山田祐一郎
- Organizer
  第16回日本病態プロテアーゼ学会
- Place of Presentation
  大阪府豊中市
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] マイクロアレイ解析による糖尿病性腎症感受性マイクロRNAの同定2011
- Author(s)
  藤田浩樹、森井宰、藤田麻貴、高嶋悟、小川和孝、三ケ田敦史、菅沼由美、清水尚子、清水辰徳、佐藤雄大、細葉美穂子、月山克史、成田琢磨、山田祐一郎
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌プリンスホテル国際館パミール
- Data Source
  KAKENHI-PROJECT-23591177
[Presentation] インクレチンから見た糖代謝・骨代謝の機能連関2011
- Author(s)
  山田祐一郎
- Organizer
  第13回日本骨粗鬆学会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] マイクロアレイ解析による糖尿病性腎症感受性マイクロRNAの同定2011
- Author(s)
  藤田浩樹、森井宰、藤田麻貴、高嶋悟、小川和孝、三ケ田敦史、菅沼由美、清水尚子、清水辰徳、佐藤雄大、細葉美穂子、月山克史、成田琢磨、山田祐一郎
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23591177
[Presentation] シタグリプチン投与で食後過血糖が改善したミトコンドリア糖尿病の一例2010
- Author(s)
  山田祐一郎
- Organizer
  第48回日本糖尿病学会東北地方会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-22390183
[Presentation] 消化管ホルモンGIPによる肝臓の糖代謝調節機構の検討2008
- Author(s)
  山田耕太郎
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2008-05-26
- Data Source
  KAKENHI-PROJECT-19591032
[Presentation] GIPシグナルの遮断は加齢に伴う耐糖能障害を改善する2008
- Author(s)
  山田千積
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2008-05-26
- Data Source
  KAKENHI-PROJECT-19591032
[Presentation] インスリン分泌指標SUITはインスリン治療必要性の鑑別に有用である2008
- Author(s)
  山田麻里子
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2008-05-26
- Data Source
  KAKENHI-PROJECT-19591032

1. FUJITA Hiroki (30333933)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. SEINO Yutaka (40030986)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. HOSOKAWA Masaya (50343231)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MATSUMOTO Shinichi (70359834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. KOIZUMI Akio (50124574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YOSHINAGA Takeo (30025663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 和田安彦 (10261653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大浦敏博 (10176828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NARITA Takuma (70282168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TSUKIYAMA Katushi (10359797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TERADA Yukihiro (10260431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. ISHIDA Hitoshi (80212893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YANO hideki (30288576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SEINO Susumu (80236067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANAKA Koichi (20115877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJIMOTO Yasuhiro (80335281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MAEKAWA Taira (80229286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUMI Shoichiro (80252906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SUNAMURA Makoto (10201584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUSHIKI Tohru (20135544)

# of Collaborated Projects: 1 results

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22. 永田英生 (50308897)

# of Collaborated Projects: 1 results

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23. 岩田博夫 (30160120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 南幸太郎 (80334176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 津田謹輔 (10180001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 塩谷隆信 (90170852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 津浦佳之 (90314195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 黒瀬健 (90264374)

# of Collaborated Projects: 1 results

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29. 井原裕 (50322160)

# of Collaborated Projects: 1 results

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30. 佐藤雄大 (40709127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. 桑田仁司 (80771469)

# of Collaborated Projects: 1 results

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32. JOHNSON John H

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. FUJIMOTO Wilfred Y

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. JOMORI Takahito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. NEWGARD Chri

# of Collaborated Projects: 1 results

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36. NEWGARD Christopher B

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 久保田章

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 斉藤治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 渡辺理江

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 大和孝子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 今井由美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMADA Yuichiro 山田 祐一郎

山田 祐一郎 ヤマダ ユウイチロウ

YAMAMOTO Yuichiro 山本 祐一郎

山田 裕一郎 ヤマダ ユウイチロウ

Research Projects

Research Products

Co-Researchers

Development of diet therapy aiming at extending healthy life expectancy based on GIP signal suppressionPrincipal Investigator

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Binding of sperm and oocyte induced by gut factor: Novel strategy for treatment of male infertilityPrincipal Investigator

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Research on the association of GIP and metabolic diseasesPrincipal Investigator

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機能性食品による消化管因子分泌調節機構に関する研究Principal Investigator

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Study on insulinoropic mechanisms co-operated by GLP-1 and GIPPrincipal Investigator

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Study on metabolism in vivo mediated by gut hormonePrincipal Investigator

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YAMADA Yuichiro 山田祐一郎

山田祐一郎ヤマダユウイチロウ

YAMAMOTO Yuichiro 山本祐一郎

山田裕一郎ヤマダユウイチロウ