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YAMADA Yuichiro  山田 祐一郎

ORCIDConnect your ORCID iD *help
… Alternative Names

YAMAMOTO Yuichiro  山本 祐一郎

山田 裕一郎  ヤマダ ユウイチロウ

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Researcher Number 60283610
Other IDs
External Links
Affiliation (Current) 2022: 株式会社関西メディカルネット(関西電力医学研究所), 糖尿病研究センター, センター長
Affiliation (based on the past Project Information) *help 2020: 株式会社関西メディカルネット(関西電力医学研究所), 糖尿病研究センター, センター長
2018 – 2019: 秋田大学, 医学系研究科, 教授
2011 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授
2013: 秋田大学, 大学院医学系研究科, 教授
2009 – 2012: Akita University, 大学院・医学系研究科, 教授 … More
2006 – 2008: 秋田大学, 医学部, 教授
2005: Kyoto University, Graduate School of Medicine, Associate Professor, 大学院・医学研究科, 助教授
2005: 京都大学, 大学院医学研究科, 助教授
1998 – 2005: 京都大学, 医学研究科, 助教授
1998 – 1999: 京都大学, 大学院・医学研究科, 助教授
1997: 京都大学, 大学院・医学研究科, 助手
1996 – 1997: Graduate School of Medicine, Kyoto Univ., 医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Metabolomics / Eating habits, studies on eating habits / Obstetrics and gynecology / Endocrinology / Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Kidney internal medicine / General surgery / 内分泌・代謝学 / Hygiene / Metabolomics / Metabolomics
Keywords
Principal Investigator
GIP / インクレチン / 糖尿病 / GLP-1 / 肥満 / incretin / diabetes / obesity / 栄養学 / 遺伝子欠損マウス … More / SNP / 節約遺伝子 / 分子遺伝学 / シグナル伝達 / 食品 / αグルコシダーゼ / 生理活性 / 不妊 / 脂肪細胞 / 骨代謝 / Knockout mice / 骨粗鬆症 / Incretin / knockout mouse / osteoporosis / エネルギー代謝 / energy expenditure / 加齢 / 生活習慣病 / 老化 / 消化管ホルモン / 病態栄養学 / 糖代謝 … More
Except Principal Investigator
GIP / 糖尿病性腎症 / インクレチン / 糖尿病 / LPI / 生体膵島移植 / 生体ドナー / 1型糖尿病 / 膵β細胞 / GIP受容体 / PCR-SSCP / CREM / cAMP / PKA / ATF2 / インスリン分泌 / ノックアウトマウス / Osler-Rendu-Weber / SLC7A7 / 遺伝疫学 / 遺伝性疾患 / 創始者変異 / マススクリーニング / Tet expression system / GLUT2 / GLP-1 / 腹腔鏡手術 / 免疫抑制剤 / マウスモデル / c-JunNH(2)-terminal kinase / アポトーシス / 酸化ストレス / マイクロRNA / ケモカイン / 遺伝子 / 変異 / 糖輸送担体 / 電位依存性カルシウム・チャネル / PCR-SSCP法 / 転写調節 / Diabetes Mellitus / Gene / Mutation / Pancreatic beta cell / Glucose Transporter / Voltage-dependent Calcium Channel / GIP Receptor / インスリン遺伝子 / グルコース応答性 / CaMKIV / CRE / CRE-BP1 / CBP / p300 / TBP / カルシウムチャネル / calmodulin-dependent protein kinase IV / CRE-BPl / insulin gene / glucose-responsive / CaMK TV / GIP受容体欠損マウス / インスリン抵抗性 / 高脂肪食負荷 / GIPシグナル伝達 / ジーンターゲティング / GIP receptor deficient mice / GIP modulation / Insulin secretion / Insulin resistance / High fat diet / Diabetes mellitus / 突然変異 / 輸送蛋白 / SL7A7 / P410X / 多のう胞 / プロインスリン / Osler-Rendu-wever / ベータ細胞 / トランスポーター / OCTN2 / 心肥大 / Hartnup / 加齢 / mutations / transporters / R410X / polycystic / proinsulin / 膵β細胞株 / SAGE法 / 転写因子 / 標的遺伝子 / 分化・増殖 / 膵Β細胞株 / 膵β細胞の発生と機能 / Tet Expression System / pancreatic β-cell line / SAGE / Transcription factor / Target gene / Proliferation and differentiation / 遺伝病 / 雑交配 / 遺伝的ドリフト / ボトルネック現象 / 劣性 / 隔離 / プロテオミックス / 集団的遺伝学 / 社会的隔離 / 地理的隔離 / 構造異常 / 嚢胞性腎症 / Osler-Rendu-Weber病 / 早期診断 / 家族性甲状腺腫 / epidemiological genetic / diseases genetic / nonrandom mating / genetic drifts / bottle neck / recessive / isolation / proteomics / 生体時計 / 時計遺伝子 / 膵内分泌 / インスリン / CLOCK / BMAL-1 / CRY1 / CRY2 / circadian clock / insulin secretion / 脂肪細胞 / 骨芽細胞 / incretin / pancreatic beta cells / adipocyte / osteoblast / 膵島移植分離技術 / 心臓死ドナー / GMP施設 / 生体膵島移埴 / 膵島分離技術 / インスリン依存状態糖尿病 / 膵島移植 / GMP / ISO9001 / ブタ膵島 / 膵管保護 / 二層法膵保存 / Living donor islet transplantation / Living donor / Islet isolation method / Non-heart-beating donor / GMP facility / Type 1 diabetes / 幹細胞 / 糖尿病治療 / バイオ人工膵 / β細胞 / 膵再生 / 膵切除 / 再生医療 / 分化誘導 / バイオ人工膵臓 / 血管新生 / stem cell / therapy for diabetes mellitus / bio-artificial pancreas / beta-cell / pancreatic regeneration / pancreatectoy / regenerative medicine / 内科 Less
  • Research Projects

    (24 results)
  • Research Products

    (54 results)
  • Co-Researchers

    (41 People)
  •  Development of diet therapy aiming at extending healthy life expectancy based on GIP signal suppressionPrincipal Investigator

    • Principal Investigator
      Yamada Yuichiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      株式会社関西メディカルネット(関西電力医学研究所)
      Akita University
  •  The role of GIP in the pathogenesis of diabetic nephropathy and its renal protective effects

    • Principal Investigator
      FUJITA HIROKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Akita University
  •  The role of GLP-1/DPP-4 signaling in diabetic nephropathy and its therapeutic potential

    • Principal Investigator
      FUJITA HIROKI
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Akita University
  •  Binding of sperm and oocyte induced by gut factor: Novel strategy for treatment of male infertilityPrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Akita University
  •  Identification of microRNAs involved in the development of diabetic nephropathy

    • Principal Investigator
      FUJITA HIROKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Akita University
  •  Research on the association of GIP and metabolic diseasesPrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Akita University
  •  機能性食品による消化管因子分泌調節機構に関する研究Principal Investigator

    • Principal Investigator
      山田 祐一郎
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Akita University
  •  Role of SOD in the pathogenesis of diabetic nephropathy

    • Principal Investigator
      FUJITA Hiroki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Akita University
  •  Study on insulinoropic mechanisms co-operated by GLP-1 and GIPPrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Akita University
  •  生体ドナーからの膵島移植・再生医療によるインスリン依存状態糖尿病治療の確立

    • Principal Investigator
      MATSUMOTO Shinichi
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General surgery
    • Research Institution
      Fujita Health University
  •  Studies on regenerative medicine for severe diabetes mellitus by stem cell biology

    • Principal Investigator
      SUMI Shoichiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  Study on metabolism in vivo mediated by gut hormonePrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Kyoto University
  •  Gut-peptides regulate metabolism in whole body.

    • Principal Investigator
      HOSOKAWA Masaya, 清野 裕
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto University
  •  Living donor islet transplantation for the treatment of sever diabetes

    • Principal Investigator
      MATSUMOTO Shinichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  Analysis of the role of clock-associated-gene in regulating the fumction of pancreatic endocrine

    • Principal Investigator
      HOSOKAWA Masaya, 黒瀬 健
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto University
  •  消化管シグナルのネットワークと糖尿病発症の解析Principal Investigator

    • Principal Investigator
      山田 祐一郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Impact of mutations and polymorphisms in transporter families on population health

    • Principal Investigator
      KOIZUMI Akio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      KYOTO UNIVERSITY
  •  Analysis of transcriptional network in pancreatic β-cells

    • Principal Investigator
      SEINO Yutaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      KYOTO UNIVERSITY
  •  Extended linkage disequilibrium mapping based on a founder effect attributable to historical and genetic isolation

    • Principal Investigator
      KOIZUMI Akio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      KYOTO UNIVERSITY
  •  Roles of incretin -Analysis of incretin receptor-deficient micePrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      KYOTO UNIVERSITY
  •  Study on a network of gut signals and development of diabetesPrincipal Investigator

    • Principal Investigator
      YAMADA Yuichiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Characterizetion of glucose-induced signal transduction and its impairment in type 2 diabete

    • Principal Investigator
      SEINO Yutaka
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  Generation and analysis of GIP Receptor deficient mice

    • Principal Investigator
      YANO hideki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Chiba University
  •  A study on the beta-Cell glucose sensors in insulin secretion : The relationship between dysfunction of glucose sensors and development of diabetes mellitus

    • Principal Investigator
      SEINO Yutaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY

All 2021 2020 2019 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 2001

All Journal Article Presentation Patent

  • [Journal Article] Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms2021

    • Author(s)
      Kato Shunsuke、Sato Takehiro、Fujita Hiroki、Kawatani Masahiro、Yamada Yuichiro
    • Journal Title

      Scientific Reports

      Volume: 11

    • DOI

      10.1038/s41598-021-88612-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03171
  • [Journal Article] GLP-1 Receptor Signaling Differentially Modifies the Outcomes of Sterile vs Viral Pulmonary Inflammation in Male Mice2020

    • Author(s)
      Sato T, Shimizu T, Fujita H, Imai Y, Drucker DJ, Seino Y, Yamada Y
    • Journal Title

      Endocrinology

      Volume: 161(12)

    • DOI

      10.1210/endocr/bqaa201

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-18H03171
  • [Journal Article] Inhibition of GIP signaling extends lifespan without caloric restriction2019

    • Author(s)
      Hoizumi Manabu、Sato Takehiro、Shimizu Tatsunori、Kato Shunsuke、Tsukiyama Katsushi、Narita Takuma、Fujita Hiroki、Morii Tsukasa、Sassa Mariko Harada、Seino Yutaka、Yamada Yuichiro
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 513 Pages: 974-982

    • DOI

      10.1016/j.bbrc.2019.04.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H03171
  • [Journal Article] Magnitude of slowing gastric emptying by glucagon‐like peptide‐1 receptor agonists determines the amelioration of postprandial glucose excursion in Japanese patients with type?2 diabetes2019

    • Author(s)
      Suganuma Yumi、Shimizu Tatsunori、Sato Takehiro、Morii Tsukasa、Fujita Hiroki、Harada Sassa Mariko、Yamada Yuichiro
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Pages: 389-399

    • DOI

      10.1111/jdi.13115

    • NAID

      120007169375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03171
  • [Journal Article] DPP-4 inhibition with alogliptin on top of anigiotensin II type 1 receptor blockage ameliorates albuminuria via up-regulation of SDF-1a in type 2 diabetic patients with incipient nephropathy2014

    • Author(s)
      Fujita H, Taniai H, Murayama H, Ohshiro H, Sato S, Kikuchi N, Komatsu T, Komatsu Ko, Komatsu Ka, Narita T, Yamada Y
    • Journal Title

      Endocr J

      Volume: 61 Pages: 159-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] Effects of miglitol, sitagliptin, and initial combination therapy with both on plasma incretins’ responses to a mixed meal and visceral fat in over-weight Japanese patients with type 2 diabetes. “The MASTER randomized, controlled trial”2014

    • Author(s)
      Mikada A, Narita T, Yokoyama H, Yamashita R, Horikawa Y, Tsukiyama K, Yamada Y
    • Journal Title

      Diabetes Res Clin Pract

      Volume: 106 Pages: 538-547

    • DOI

      10.1016/j.diabres.2014.09.040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] The protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential2014

    • Author(s)
      Fujita H, Morii T, Fujishima H, Sato T, Shimizu T, Hosoba M, Tsukiyama K, Narita T, Takahashi T, Drucker DJ, Seino Y, Yamada Y
    • Journal Title

      Kidney Int

      Volume: 85 Pages: 579-589

    • DOI

      10.1038/ki.2013.427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals.2014

    • Author(s)
      Itoh K., Moriguchi R., Yamada Y., Fujita M., Yamato T., Oumi M., Holst JJ., Seino Y.
    • Journal Title

      Nutr Res.

      Volume: 34 Pages: 653-660

    • DOI

      10.1016/j.nutres.2014.07.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501019, KAKENHI-PROJECT-25670692, KAKENHI-PROJECT-26460826
  • [Journal Article] Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor deficient mice.2014

    • Author(s)
      Okawa T, Kamiya H, Himeno T, Kato J, Seino Yus, Fukami A, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Hayashi Y, Harada N, Yamada Y, Inagaki N, Seino Yut, Oiso Y, Nakamura J
    • Journal Title

      J Diabetes Invest

      Volume: 5 Pages: 31-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] Effects of consumption of main and side dishes with white rice on postprandial glucose, insulin, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 responses in healthy Japanese men.2014

    • Author(s)
      Kameyama N, Maruyama C, Matsui S, Araki R, Yamada Y, Maruyama T
    • Journal Title

      Br J Nutr

      Volume: 111 Pages: 1632-40

    • DOI

      10.1017/s0007114513004194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes.2014

    • Author(s)
      Omar BA, Liehua L, Yamada Y, Seino Y, Marchetti P, Ahrén B
    • Journal Title

      Diabetologia

      Volume: 57 Pages: 1876-1883

    • DOI

      10.1007/s00125-014-3299-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] Quantitative Analytical Method for Determining the Levels of Gastric Inhibitory Polypeptides GIP and GIP in Human Plasma Using LC-MS/MS/MS2013

    • Author(s)
      Miyachi A, Murase T, Yamada Y, Osonoi T, Harada KI
    • Journal Title

      J Proteome Res

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] A quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS.2013

    • Author(s)
      Miyachi A, Murase T, Yamada Y, Osonoi T, Harada KI
    • Journal Title

      J Proteome Res

      Volume: 12 Pages: 2690-99

    • DOI

      10.1021/pr400069f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Journal Article] Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice2012

    • Author(s)
      Fujita H, Fujishima H, Morii T, Sakamoto T, Komatsu K, Hosoba M, Narita T, Takahashi K, Takahashi T, Yamada Y
    • Journal Title

      Hypertens Res

      Volume: 35(2) Pages: 213-220

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] Comparisons of the effects of 12-week administration of miglitol and voglibose on the responses of plasma incretins after a mixed meal in Japanese type 2 diabetic patients2012

    • Author(s)
      Narita T, Yokoyama H, Yamashita R, Sato T, Hosoba M, Morii T, Fujita H, Tsukiyama K, Yamada Y
    • Journal Title

      Diabetes Obes Metab

      Volume: 14(3) Pages: 283-287

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice2012

    • Author(s)
      Fujita H, Fujishima H, Takahashi K, Sato T, Shimizu T, Morii T, Shimizu T, Shirasawa T, Qi Z, Breyer MD, Harris RC, Yamada Y, Takahashi T
    • Journal Title

      Metabolism

      Volume: 61(12) Pages: 1714-1724

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] Efficacy and safety of patient-directed titration of once-daily pre-dinner premixed biphasic insulin aspart 70/30 injection in Japanese type 2 diabetic patients with oral antidiabetic drug failure: STEP-AKITA study2011

    • Author(s)
      Narita T, Goto T, Suganuma Y, Hosoba M, Morii T, Sato T, Fujita H, Miura T, Shimotomai T, Yamada Y, Kakei M
    • Journal Title

      J Diabetes Invest

      Volume: 2(1) Pages: 63-70

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy2011

    • Author(s)
      Fujita H, Sakamoto T, Komatsu K, Fujishima H, Morii T, Narita T, Takahashi T, Yamada Y
    • Journal Title

      Hypertens Res

      Volume: 34(12) Pages: 1302-1308

    • NAID

      10030278001

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] Phenotypical variety of insulin resistance in a family with a novel mutation of the insulin receptor gene2010

    • Author(s)
      Takahashi I, Yamada Y, Kadowaki H, Horikoshi M, Kadowaki T, Narita T, Tsuchida S, Noguchi A, Koizumi A, Takahashi T
    • Journal Title

      Endocr J

      Volume: 57(6) Pages: 509-516

    • NAID

      10029585142

    • Data Source
      KAKENHI-PROJECT-22390183
  • [Journal Article] Reduction of renal superoxide dismutase in progressive diabetic nephropathy.2009

    • Author(s)
      Hiroki Fujita, Hiromi Fujishima, Shinsuke Chida, Keiko Takahashi, Zhonghua Qi, Yukiko Kanetsuna, Matthew Breyer, Raymond Harris, Yuichiro Yamada, Takamune Takahashi
    • Journal Title

      J Am Soc Nephrol 20

      Pages: 1303-1313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590943
  • [Journal Article] Miglitol induces prolonged and enhanced glucagon-like peptide-1 and reduced gastric inhibitory polypeptide responses after ingestion of a mixed meal in Japanese type 2 diabetic patients2009

    • Author(s)
      Narita T, Katsuura Y, Sato T, Hosoba M, Fujita H, Morii T, Yamada Y
    • Journal Title

      Diabet Med 26(2)

      Pages: 187-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Reduction of renal superoxide dismutase in progressive diabetic nephropathy2009

    • Author(s)
      藤田浩樹, 山田祐一郎
    • Journal Title

      Journal of the American Society of Nephrology 20

      Pages: 1303-1313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590943
  • [Journal Article] The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.2008

    • Author(s)
      Chizumi Yamada
    • Journal Title

      Endocrinology 149

      Pages: 574-579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] A novel gastric inhibitory polypeptide (GIP) receptor splice variant influences GIP sensitivity of pancreatic β-cells in obese mice2008

    • Author(s)
      Harada N, Yamada Y, Tsukiyama K, Yamada C, Nakamura Y, Mukai E, Hamasaki A, Liu X, Yamada K, Sasaki M, Toyoda K, Seino Y, Inagaki N
    • Journal Title

      Am J Physiology Endocrinol Metab 294(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] The murine glucagon-like peptide-1 receptor is essential for control of bone resorption2008

    • Author(s)
      Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, Tanaka K, Drucker DJ, Seino Y, Inagaki N
    • Journal Title

      Endocrinology 149(2)

      Pages: 574-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice2008

    • Author(s)
      Naitoh R, Miyawaki K, Harada N, Mizunoya W, Toyoda K, Fushiki T, Yamada Y, Seino Y, Inagaki N
    • Journal Title

      Biochem Biophys Res Commun 376(1)

      Pages: 21-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Glycemic instability in type1 diabetic patients : Possible role of ketosis or ketoacidosis at onset of diabetes2008

    • Author(s)
      Sassa M, Yamada Y, Hosokawa M, Fukuda K, Fujimoto S, Toyoda K, Tsukiyama K, Seino Y, Inagaki N
    • Journal Title

      Diabetes Res Clin Pract 81(2)

      Pages: 190-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Insulin gene is a target in activin receptor-like kinase 7 signaling pathway in pancreatic beta-cells2008

    • Author(s)
      Watanabe R, Shen ZP, Tsuda K, Yamada Y
    • Journal Title

      Biochem Biophys Res Commun 377(3)

      Pages: 867-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes.2007

    • Author(s)
      Chizumi Yamada
    • Journal Title

      Biochem Biophys Res Commun 364

      Pages: 175-180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes2007

    • Author(s)
      Yamada C, Tsukiyama K, Yamada K, Yamane S, Harada N, Miyawaki K, Seino Y, Inagaki N, Yamada Y
    • Journal Title

      Biochem Biophys Res Commun 364(1)

      Pages: 175-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Effect of selective cyclooxygenase-2 (COX-2) inhibitor treatment on glucose-stimulated insulin secretion in C57BL/6 mice2007

    • Author(s)
      Fujita H, Kakei M, Fujishima H, Morii T, Yamada Y, Qi Z, Breyer MD
    • Journal Title

      Biochem Biophys Res Commun 363(1)

      Pages: 37-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Effects of long-term pravastatin treatment on serum and urinary monocyte chemoattractant protein-1 levels and renal function in type 2 diabetic patients with normoalbuminuria2007

    • Author(s)
      Fujita H, Koshimura J, Sato T, Miura T, Sasaki H, Morii T, Narita T, Kakei M, Ito S, Yamada Y
    • Journal Title

      Ren Fail 29(7)

      Pages: 791-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] Clock Gene Defect Disrupts Light-Dependency of Autonomic Nerve Activity2007

    • Author(s)
      Ikeda H, Yong Q, Kurose T, Todo T, Mizunoya W, Fushiki T, Seino Y, Yamada Y
    • Journal Title

      Biochem Biophys Res Commun 364(3)

      Pages: 457-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Journal Article] SUIT, secreatory units of islets in transplantation : an index for therapeutic management of islet transplanted patients and its application to type 2 diabetes.2006

    • Author(s)
      Yamada Y, Matsumoto S et al.
    • Journal Title

      Diabetes Res Clin Pract 74

      Pages: 222-226

    • Data Source
      KAKENHI-PROJECT-18109010
  • [Journal Article] Physiology of GIP--a lesson from GIP receptor knockout mice.2004

    • Author(s)
      Yamada Y
    • Journal Title

      Horm Metab Res 36(11-12)

      Pages: 771-774

    • Data Source
      KAKENHI-PROJECT-13204042
  • [Journal Article] 心停止ドナーからの膵島移植によってインスリン離脱した1型糖尿病の1症例2004

    • Author(s)
      山田祐一郎, 松本慎一ら
    • Journal Title

      糖尿病 47

      Pages: 945-950

    • NAID

      10014466439

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390376
  • [Journal Article] Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.2001

    • Author(s)
      Yamada Y
    • Journal Title

      Diabetes Metab Res Rev 17

      Pages: 213-216

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13204042
  • [Journal Article] Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.2001

    • Author(s)
      Yamada Y
    • Journal Title

      Diabetes Metab ResRev 1 7

      Pages: 213-216

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13204042
  • [Patent] インスリン抵抗性及び/又は肥満の予防剤もしくは改善剤2001

    • Inventor(s)
      清野裕, 宮脇一真, 山田祐一郎, 坂信広, 鍔本義治, 武田基弘, 橋本洋幸, 山下篤行, 城森孝仁
    • Industrial Property Rights Holder
      清野裕, 宮脇一真, 山田祐一郎, 坂信広, 鍔本義治, 武田基弘, 橋本洋幸, 山下篤行, 城森孝仁
    • Industrial Property Number
      2001-144416
    • Filing Date
      2001-05-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13204042
  • [Presentation] Rice cracker made from resistant starch-containing rice ameliorate post-prandial hyperglycemia2019

    • Author(s)
      Kuwata H, Fujiwara Y, Yabe D, Watanabe T, Sasaki T, Higuchi Y, Saito Y, Arao H, Hirayama M, Goto H, Seino Y, Watanabe K, Yamada Y, Fujita N
    • Organizer
      11th Scientific Meeting of the Asian Association for the Study of Diabetes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03171
  • [Presentation] 177 精巣におけるGIPシグナルの低下は肥満・糖尿病における男性不妊をおこす2014

    • Author(s)
      清水辰徳、月山克史、佐藤雄大、藤田浩樹、成田琢磨、寺田幸弘、山田祐一郎
    • Organizer
      第87回日本内分泌学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-25670692
  • [Presentation] Extrapancreatic effects of GIP and GLP-12013

    • Author(s)
      Yamada Y
    • Organizer
      Beta cell workshop 2013 Kyoto
    • Place of Presentation
      京都市
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] Extrapancreatic effects of GIP and GLP-1 Beta Cell Workshop 20132013

    • Author(s)
      Yamada Y
    • Organizer
      Kyoto
    • Place of Presentation
      京都府京都市
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] インクレチンの糖代謝2013

    • Author(s)
      山田祐一郎
    • Organizer
      第86回日本内分泌学会学術集会
    • Place of Presentation
      仙台市
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] インクレチンの糖代謝2013

    • Author(s)
      山田祐一郎
    • Organizer
      第86回日本内分泌学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] Mass spectrometry-based simultaneous quantification of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma2012

    • Author(s)
      Yamada Y
    • Organizer
      9th IDF-WPR congress
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] インクレチンの生理作用2011

    • Author(s)
      山田祐一郎
    • Organizer
      第16回日本病態プロテアーゼ学会
    • Place of Presentation
      大阪府豊中市
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] マイクロアレイ解析による糖尿病性腎症感受性マイクロRNAの同定2011

    • Author(s)
      藤田浩樹、森井宰、藤田麻貴、高嶋悟、小川和孝、三ケ田敦史、菅沼由美、清水尚子、清水辰徳、佐藤雄大、細葉美穂子、月山克史、成田琢磨、山田祐一郎
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌プリンスホテル国際館パミール
    • Data Source
      KAKENHI-PROJECT-23591177
  • [Presentation] インクレチンから見た糖代謝・骨代謝の機能連関2011

    • Author(s)
      山田祐一郎
    • Organizer
      第13回日本骨粗鬆学会
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] マイクロアレイ解析による糖尿病性腎症感受性マイクロRNAの同定2011

    • Author(s)
      藤田浩樹、森井宰、藤田麻貴、高嶋悟、小川和孝、三ケ田敦史、菅沼由美、清水尚子、清水辰徳、佐藤雄大、細葉美穂子、月山克史、成田琢磨、山田祐一郎
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-23591177
  • [Presentation] シタグリプチン投与で食後過血糖が改善したミトコンドリア糖尿病の一例2010

    • Author(s)
      山田祐一郎
    • Organizer
      第48回日本糖尿病学会東北地方会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2010-11-06
    • Data Source
      KAKENHI-PROJECT-22390183
  • [Presentation] 消化管ホルモンGIPによる肝臓の糖代謝調節機構の検討2008

    • Author(s)
      山田耕太郎
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2008-05-26
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Presentation] GIPシグナルの遮断は加齢に伴う耐糖能障害を改善する2008

    • Author(s)
      山田千積
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2008-05-26
    • Data Source
      KAKENHI-PROJECT-19591032
  • [Presentation] インスリン分泌指標SUITはインスリン治療必要性の鑑別に有用である2008

    • Author(s)
      山田麻里子
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2008-05-26
    • Data Source
      KAKENHI-PROJECT-19591032
  • 1.  FUJITA Hiroki (30333933)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 9 results
  • 2.  SEINO Yutaka (40030986)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HOSOKAWA Masaya (50343231)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MATSUMOTO Shinichi (70359834)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  KOIZUMI Akio (50124574)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  YOSHINAGA Takeo (30025663)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  和田 安彦 (10261653)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  大浦 敏博 (10176828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NARITA Takuma (70282168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  TSUKIYAMA Katushi (10359797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  TERADA Yukihiro (10260431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  ISHIDA Hitoshi (80212893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YANO hideki (30288576)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SEINO Susumu (80236067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TANAKA Koichi (20115877)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUJIMOTO Yasuhiro (80335281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MAEKAWA Taira (80229286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SUMI Shoichiro (80252906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TABATA Yasuhiko (50211371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SUNAMURA Makoto (10201584)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FUSHIKI Tohru (20135544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  永田 英生 (50308897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  岩田 博夫 (30160120)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  南 幸太郎 (80334176)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  津田 謹輔 (10180001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  塩谷 隆信 (90170852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  津浦 佳之 (90314195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  黒瀬 健 (90264374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  井原 裕 (50322160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  佐藤 雄大 (40709127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  桑田 仁司 (80771469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  JOHNSON John H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  FUJIMOTO Wilfred Y
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  JOMORI Takahito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  NEWGARD Chri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  NEWGARD Christopher B
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  久保田 章
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  斉藤 治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  渡辺 理江
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  大和 孝子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  今井 由美子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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