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Adachi Motoyasu  安達 基泰

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ADACHI Motoyasu  安達 基泰

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Researcher Number 60293958
Other IDs
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Affiliation (Current) 2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員
Affiliation (based on the past Project Information) *help 2021 – 2024: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員
2020 – 2022: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, 上席研究員(定常)
2019: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, グループリーダー(定常)
2016 – 2018: 国立研究開発法人量子科学技術研究開発機構, 高崎量子応用研究所 東海量子ビーム応用研究センター, 上席研究員(定常)
2017: 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門・量子ビーム応用研究センター, グループリーダー … More
2016: 国立研究開発法人量子科学技術研究開発機構, 東海量子ビーム応用研究センター, 上席研究員
2016: 国立研究開発法人量子科学技術研究開発機構, 量子科学技術研究開発機構・東海量子ビーム応用研究センター, 上席研究員
2015: 国立研究開発法人 量子科学技術研究開発機構, 東海量子ビーム応用研究センター, 上席研究員
2015: 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 量子ビーム応用研究センター, グループリーダー
2014: 独立行政法人日本原子力研究開発機構, 原子力科学研究部門 量子ビーム応用研究センター, サブリーダー
2014: 独立行政法人日本原子力研究開発機構, 原子力科学研究部門, サブリーダー
2013: 日本原子力研究開発機構, 研究員
2013: 独立行政法人日本原子力研究開発機構, 原子力科学研究部門 量子ビーム応用研究センター, 研究副主幹
2013: 独立行政法人日本原子力研究開発機構, 原子力科学研究部門・量子ビーム応用研究センター, 研究副主幹
2013: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究センター, 研究副主幹
2012 – 2013: 独立行政法人日本原子力研究開発機構, その他部局等, 研究員
2010 – 2012: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹
2011: 独立行政法人日本原子力研究開発機構, 子ビーム応用研究部門, 研究副主幹
2008 – 2010: Japan Atomic Energy Agency, 量子ビーム応用研究部門, 研究職
2009: 日本原子力研究会発機構, 量子ビーム応用研究部門, 研究員
2009: Japan Atomic Energy Agency, 独立行政法人日本原子力研究開発機構・量子ビーム応用研究部門, 研究職
2006 – 2007: Quantum Beam Science Directorate, Japan Atomic Energy Agency, Researcher, 量子ビーム応用研究部門, 研究員
2005: 独立行政法人, 日本原子力研究開発機構・量子ビーム応用研究部門, 研究員
2005: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 任期付研究員
2001 – 2003: 京都大学, 農学研究科, 助手
1997 – 2001: 京都大学, 食糧科学研究所, 助手
1999: 京都大学, 食糧化学研究所, 助手
1998: KYOTO UNIVERSITY,Research Institute for Food Science, Research Associate, 食糧学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Transition State Control / 生物資源の変換と展開 / Structural biochemistry / Living organism molecular science / 食品科学・栄養科学
Except Principal Investigator
食品科学・栄養科学 / Structural biochemistry / Basic Section 36020:Energy-related chemistry … More / Physical pharmacy / Basic Section 49010:Pathological biochemistry-related / Basic Section 38030:Applied biochemistry-related / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Transformative Research Areas, Section (II) / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Living organism molecular science / Food science / Applied pharmacology / Environmental pharmacy Less
Keywords
Principal Investigator
結晶構造解析 / 中性子 / 酵素 / HIV / プロテアーゼ / グリシニン / drug / hydrogen / protein / crystal … More / neutron / 補酵素 / transgenic plant / physicochemical function / crystal structure / glycinin / cruciferin / 形質転換植物 / 加工特性 / 高次構造 / クルシフェリン / 不活性化酵素 / 薬剤耐性 / HIVプロテアーゼ / 構造解析 / 結晶 / システイン / 構造活性相関 / CYP3A4 / 医薬品代謝 / シトクロームP450 / 大腸菌発現 / P450 / レトロウイルス / エイズ / コレステロール / 微生物発現 / 品質変換 / X線結晶構造解析 / ダイズタンパク質 … More
Except Principal Investigator
X線結晶構造解析 / チトクロームP450 / glycinin / コングリシニン / グリシニン / 薬物代謝酵素 / タンパク質 / 構造活性相関 / 光捕集タンパク質 / 増感太陽電池 / 乳化性 / 加工特性 / soybean proteins / ダイズタンパク質 / X-ray crystallography / conglycinin / 遺伝子多型 / 阻害剤 / 蛋白質 / 結晶構造 / 水和水 / 11Sグロブリン / 7Sグロブリン / 遺伝性痙性対麻痺 / 中性子結晶構造解析 / SFX / トパキノン / 色素増感太陽電池 / 振電コヒーレント相互作用 / 検査法 / 新型コロナウイルス / PLpro / Mpro / SARS-CoV / プロテアーゼ / ビオチン / ストレプトアビジン / 酵素活性 / 重水素医薬品 / 速度論的同位体効果 / CYP2C9 / 量子コヒーレント伝導 / 自己組織化 / C型フィコシアニン / 中性子線結晶解析 / 温度応答ポリマー / 水分子 / 相転移 / 結晶成長エントロピー / ゾル / ゲル / LCST型温度応答ポリマー / タンパク質結晶成長 / 中性子線結晶構造解析 / protein engineering / x-ray crystallography / T4 phage lysozyme / disulfide bond / 水和構造 / T4リゾチーム / 分子間架橋 / crystallograbhy / physicochemical property / 11S globulin / 7S globulin / seed storage proteins / 溶解性 / 種子タンパク質 / 豆科種子 / 結晶化 / 構造・加工特性相関 / 結晶構造解析 / 種子貯蔵タンパク質 / bile acid-binding ability / physicochemical function / アレルゲン性 / 肝汁酸結合能 / 胆汁酸結合能 / Pichia pastoris / fission yeast / budding yeast / secretion production / vacuolar sorting / conglysinin / ミュータント / カルボキシペプチダーゼY / ピキア パストリス / 分裂酵母 / 出芽酵母 / 分泌生産 / 液胞輸送 / functional properties / recombinant / storage proteins / soybean / 構造機能相関 / β-コングリシニン / 微生物発現 / 品質変換 / 構造・機能相関 / 大豆タンパク質 / 酵素 / 生理活性 / 癌 / 酸化還元酵素 / 活性酸素種 / コガネバナ / ケシ / バイカレイン / モルヒネ / パーオキシダーゼ / 量子ビーム / 構造生物学 / 水和 / 分子認識 / 分子設計 / 創薬標的 / 中性子回折 / 放射線、X線、粒子線 / アレルギー・ぜんそく / 活性化機構 / アレルギー疾患 / ペリオスチン / 創薬標的タンパク質 / 水素原子 / 中性子解析 / Gly m Bd 30K / ツルマメ / 野生種 / ダイズ Less
  • Research Projects

    (28 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (32 People)
  •  Analysis of proton transfer in enzymatic reactions based on quantum theory

    • Principal Investigator
      村川 武志
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  CYP2U1の脱オーファン化にむけた酵素活性、及び立体構造の解明に関する研究

    • Principal Investigator
      前川 京子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Doshisha Women's College of Liberal Arts
  •  振電コヒーレント相互作用を用いた光捕集タンパク質増感太陽電池の開発

    • Principal Investigator
      田村 浩司
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 36020:Energy-related chemistry
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Establishment of method for detecting viral protease activity using affinity competition

    • Principal Investigator
      HIDAKA Koushi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Kobe University
  •  Development for quantum-theoretical approach by observing hydrogen atom positions in drug target proteinsPrincipal Investigator

    • Principal Investigator
      Adachi Motoyasu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Development of prediction and evaluation methods of KIE involving drug-metabolizing enzymes for deuterated drug design

    • Principal Investigator
      Maekawa Keiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Doshisha Women's College of Liberal Arts
  •  Development of solar cell sensitized by artificially self-assembled protein using quantum coherent conduction

    • Principal Investigator
      TAMURA Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 36020:Energy-related chemistry
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Effects of multiple binding sites of CYP2C9 on its allosteric modulation

    • Principal Investigator
      Maekawa Keiko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Doshisha Women's College of Liberal Arts
  •  Crystal structure analysis for intermediate in enzymatic reaction by using neutron beamPrincipal Investigator

    • Principal Investigator
      Adachi Motoyasu
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Transition State Control
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of a method to grow large protein crystals for neutron structural analysis

    • Principal Investigator
      Yao Min
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Hokkaido University
  •  Study on Molecular Mechanism in Drug Resistance of Virus Acid ProteasePrincipal Investigator

    • Principal Investigator
      Adachi Motoyasu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
      Japan Atomic Energy Agency
  •  Elucidation on pathophysiological significance of orphan P450 expression in tumor tissue and its application to drug discovery research

    • Principal Investigator
      Maekawa Keiko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      National Institute of Health Sciences
  •  Structural and biological studies on metabolism of active oxygen species in medicinal plants

    • Principal Investigator
      MORIMOTO Satoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Kyushu University
  •  Structural Analysis of Inhibitor Binding Site of Enzyme by Neutron CrystallographyPrincipal Investigator

    • Principal Investigator
      ADACHI Motoyasu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Japan Atomic Energy Agency
  •  Elucidation of Protein-Ligand Interactions Using Neutron Diffraction

    • Principal Investigator
      KUROKI Ryota
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Japan Atomic Energy Agency
  •  Structure‐activity relationship studies of CYP2C9 genetic variants

    • Principal Investigator
      MAEKAWA Keiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  Elucidation of Activation Mechanism of Extracellular Matrix Protein in Related to Allergosis

    • Principal Investigator
      TAMADA Taro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Japan Atomic Energy Agency
  •  Investigation of the drug-CYP3A4 interaction by the use of high resolution structure analysisPrincipal Investigator

    • Principal Investigator
      ADACHI Motoyasu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Japan Atomic Energy Agency
  •  Technological improvement for Neutron Crystallographic Analysis of Protein Structures

    • Principal Investigator
      KUROKI Ryota
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Japan Atomic Energy Agency
  •  レトロウイルス由来アスパラギン酸プロテアーゼの中性子構造解析Principal Investigator

    • Principal Investigator
      安達 基泰
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Japan Atomic Energy Agency
  •  Creation of the Intermolecular Disulfide Bonded Crystal to Observe Tertiary Structures in Different Solvent Conditions

    • Principal Investigator
      KUROKI Ryota
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Living organism molecular science
    • Research Institution
      Quantum Beam Science Directorate, Japan Atomic Energy Agency
  •  Structure-physicochemical property relationships at molecular levels of seed storage proteins

    • Principal Investigator
      UTSUMI Shigeru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      KYOTO UNIVERSITY
  •  ダイズ近縁種を利用する新ダイズ品種の開発基盤の確立

    • Principal Investigator
      UTSUMI Shigeru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      食品科学・栄養科学
    • Research Institution
      Kyoto University
  •  Structure-quality relationships at molecular level of soybean major storage proteins

    • Principal Investigator
      UTSUMI Shigeru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      KYOTO UNIVERSITY
  •  Utilization of waste protein from oil seed by improvement for its qualityPrincipal Investigator

    • Principal Investigator
      ADACHI Motayasu
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      生物資源の変換と展開
    • Research Institution
      KYOTO UNIVERSITY
  •  ダイズタンパク質グリシニンのX線結晶構造解析と血清コレステロール値低下能の強化Principal Investigator

    • Principal Investigator
      安達 基泰
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      Kyoto University
  •  Construction of yeast secretion production system of soybean proteins using mutant strains and their utilization for food

    • Principal Investigator
      UTSUMI Shigeru
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      KYOTO UNIVERSITY
  •  Quality-structure relationships of soybean storage proteins

    • Principal Investigator
      UTSUMI Shigeru
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      KYOTO UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Structural Biology in Drug Discovery: Methods, Techniques, and Practices2020

    • Author(s)
      Motoyasu Adachi, Ryota Kuroki
    • Total Pages
      17
    • Publisher
      WILEY
    • ISBN
      9781118681015
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Book] 「医療関連酵素」、酵素利用技術体系(小宮山眞監修)2010

    • Author(s)
      安達基泰、角南智子、黒木良太
    • Publisher
      エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Book] 酵素利用技術体系(第2章酵素を見る。「医療関連酵素」)(小宮山眞監修)2010

    • Author(s)
      安達基泰、角南智子、黒木良太
    • Publisher
      エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Book] 「中性子解析」, 生命科学のための機器分析ハンドブック(西村善文編)2007

    • Author(s)
      黒木良太、安達基泰、栗原和男、玉田太郎
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] タンパク質の分子論的研究はいずこへ2022

    • Author(s)
      安達 基泰
    • Journal Title

      Isotope News

      Volume: 779 Pages: 7-10

    • Open Access
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Journal Article] Neutron diffraction experiments of green fluorescent protein2021

    • Author(s)
      Shibazaki Chie, Shimizu Rumi, Kagotani Yuji, Andreas Ostermann, Tobias E. Schrader, Adachi Motoyasu
    • Journal Title

      Annual Reports / MLZ - Heinz Maier-Leibnitz Zentrum

      Volume: 2020 Pages: 52-52

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Journal Article] 水のアクセスと蛋白質ーリガンド解離の関係について2021

    • Author(s)
      米谷 佳晃, 安達 基泰
    • Journal Title

      分子シミュレーション学会会誌

      Volume: 23 Pages: 182-187

    • NAID

      40022664215

    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Journal Article] Direct Observation of the Protonation States in the Mutant Green Fluorescent Protein2020

    • Author(s)
      Chie Shibazaki, Rumi Shimizu, Yuji Kagotani, Andreas Ostermann, Tobias E. Schrader, Motoyasu Adachi
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 11 Issue: 2 Pages: 492-496

    • DOI

      10.1021/acs.jpclett.9b03252

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] 光捕集タンパク質の 2 次元電子分光2020

    • Author(s)
      篭谷勇児 、安達基泰
    • Journal Title

      OPTRONICS

      Volume: 39(464) Pages: 84-88

    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Journal Article] X-Ray diffraction experiments for drug target protein of human casein kinase II2019

    • Author(s)
      Chie Shibazaki, Shigeki Arai, Rumi Shimizu, Motoyasu Adachi
    • Journal Title

      Photon Factory Activity Report 2018

      Volume: 36 Pages: 149-149

    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] The first identification and characterization of a histidine-specific amino acid racemase, histidine racemase from a lactic acid bacterium, Leuconostoc mesenteroides subsp. sake NBRC 1024802018

    • Author(s)
      Adachi Motoyasu、Shimizu Rumi、Kato Shiro、Oikawa Tadao
    • Journal Title

      Amino Acids

      Volume: 51 Issue: 2 Pages: 331-343

    • DOI

      10.1007/s00726-018-2671-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] Hydration Structures of the Human Protein Kinase CK2α Clarified by Joint Neutron and X-ray Crystallography2018

    • Author(s)
      Shibazaki Chie、Arai Shigeki、Shimizu Rumi、Saeki Morihisa、Kinoshita Takayoshi、Ostermann Andreas、Schrader Tobias E.、Kurosaki Yuzuru、Sunami Tomoko、Kuroki Ryota、Adachi Motoyasu
    • Journal Title

      Journal of Molecular Biology

      Volume: 430 Issue: 24 Pages: 5094-5104

    • DOI

      10.1016/j.jmb.2018.09.018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] Deuterated Materials Enhancing Neutron Science for Structure Function Applications2018

    • Author(s)
      阿久津 和宏 , 安達 基泰 , 川北 至信
    • Journal Title

      JAEA-Review

      Volume: J-PARC 17-06

    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type2017

    • Author(s)
      Hiromoto Takeshi、Meilleur Flora、Shimizu Rumi、Shibazaki Chie、Adachi Motoyasu、Tamada Taro、Kuroki Ryota
    • Journal Title

      Protein Science

      Volume: 26 Issue: 10 Pages: 1953-1963

    • DOI

      10.1002/pro.3230

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Journal Article] Crystal structure analysis of human drug metabolizing enzyme CYP2C9 complexed with medicinal compound Losartan.2016

    • Author(s)
      Adachi M, Matsuzawa Y, Kuroki R, Saito Y and Maekawa K
    • Journal Title

      Photon Factory Activity Report

      Volume: 33 Pages: 364-364

    • Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Journal Article] タンパク質中性子結晶構造解析の実例と応用2014

    • Author(s)
      安達基泰、新井栄揮、廣本武史、黒木良太
    • Journal Title

      波紋

      Volume: 24巻 Pages: 45-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Journal Article] タンパク質中性子結晶構造解析の実例と応用2014

    • Author(s)
      安達 基泰 , 新井 栄揮 , 廣本 武史, 黒木 良太
    • Journal Title

      波紋

      Volume: 24 Pages: 45-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Journal Article] Seven cysteine- deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1.2012

    • Author(s)
      Nakaniwa T, Fukada H, Inoue T, Gouda M, Nakai R, Kirii Y, Adachi M, Tamada T, Segawa S, Kuroki R, Tada T, Kinoshita T
    • Journal Title

      Biochemistry

      Volume: 51 Issue: 42 Pages: 8410-8421

    • DOI

      10.1021/bi300918w

    • Data Source
      KAKENHI-PROJECT-22390010
  • [Journal Article] Crystallization and preliminary neutron diffraction studies of ADP-ribose pyrophosphatase-I from Thermus thermophilus HB82012

    • Author(s)
      Nobuo Okazaki, Motoyasu Adachi, Taro Tamada, Kazuo Kurihara, Takushi Ooga, Nobuo Kamiiya, Seiki Kuramitsu, Ryota Kuroki
    • Journal Title

      Acta Cryst

      Volume: F68 Issue: 1 Pages: 49-52

    • DOI

      10.1107/s1744309111044551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370049, KAKENHI-PROJECT-22390010, KAKENHI-PROJECT-24227002, KAKENHI-PLANNED-24107003
  • [Journal Article] Towards investigation of the inhibitorrecognition mechanisms of drug-target proteins by neutron crystallography.2012

    • Author(s)
      Kuroki R, Okazaki N, Adachi M, Ohhara T, Kurihara K, Tamada T
    • Journal Title

      Acta Crystallogr. D Biol. Crystallogr

      Volume: 66 Issue: 11 Pages: 1126-1130

    • DOI

      10.1107/s0907444910034967

    • Data Source
      KAKENHI-PROJECT-22390010
  • [Journal Article] 中性子と放射光の相補的な利用による創薬標的タンパク質の立体構造解析2010

    • Author(s)
      黒木良太、玉田太郎、栗原和男、大原高志、安達基泰
    • Journal Title

      薬学雑誌 130巻

      Pages: 657-664

    • NAID

      130000259451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] 中性子を用いた創薬標的蛋白質の立体構造解析2010

    • Author(s)
      安達基泰、黒木良太
    • Journal Title

      蛋白質核酸酵素 55巻

      Pages: 82-87

    • NAID

      40016985468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] 中性子を用いた創薬標的蛋白質の立体構造解析2010

    • Author(s)
      安達基泰、黒木良太
    • Journal Title

      タンパク質核酸酵素 55

      Pages: 82-87

    • NAID

      40016985468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Towards investigation of the inhibitor-recognition mechanisms of drug-target proteins by neutron crystallography.2010

    • Author(s)
      Kuroki, R., Okazaki, N., Adachi, M., Ohhara, T., Kurihara, K., Tamada, T.
    • Journal Title

      Acta Crystallogr D Biol Crystallogr. 66

      Pages: 1126-1130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] 中性子回折による創薬標的蛋白質の構造解析2010

    • Author(s)
      玉田太郎、安達基泰
    • Journal Title

      RADIOISOTOPES誌 59

      Pages: 299-308

    • NAID

      10026244847

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] 中性子と放射光の相補的な利用による創薬標的タンパク質の立体構造解析2010

    • Author(s)
      黒木良太、玉田太郎、栗原和男、大原高志、安達基泰
    • Journal Title

      薬学雑誌 130巻

      Pages: 657-664

    • NAID

      130000259451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] 中性子を用いた創薬標的蛋白質の立体構造解析2010

    • Author(s)
      安達基泰、黒木良太
    • Journal Title

      蛋白質核酸酵素 55巻

      Pages: 82-87

    • NAID

      40016985468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.2009

    • Author(s)
      Hidaka, K., Kimura, T., Abdel-Rahman, H.M., Nguyen, J.T., McDaniel, K.F., Kohlbrenner, W.E., Molla, A., Adachi, M., Tamada, T., Kuroki, R., Katsuki, N., Tanaka, Y., Matsumoto, H., Wang, J., Hayashi, Y., Kempf, D.J., Kiso, Y.
    • Journal Title

      J Med Chem. 52(23)

      Pages: 7604-7617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] HIV-1プロテアーゼの中性子結晶構造解析2009

    • Author(s)
      安達基泰, 黒木良太
    • Journal Title

      中性子科学会誌「波紋」 19

      Pages: 214-217

    • NAID

      130006701970

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond.2009

    • Author(s)
      Tamada, T., Kinoshita, T., Kurihara, K., Adachi, M., Ohhara, T., Imai, K., Kuroki, R., Tada, T.
    • Journal Title

      J Am Chem Soc. 131

      Pages: 11033-11040

    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography2009

    • Author(s)
      Adachi, M, et al.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America 106

      Pages: 4641-4646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography.2009

    • Author(s)
      Adachi, M., Ohhara, T., Kurihara, K., Tamada, T., Honjo, E., Okazaki, N., Arai, S., Shoyama, Y., Kimura, K., Matsumura, H., Sugiyama, S., Adachi, H., Takano, K., Mori, Y., Hidaka, K., Kimura, T., Hayashi, Y., Kiso, Y., Kuroki, R.
    • Journal Title

      Proc Natl Acad Sci USA. 106

      Pages: 4641-4646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography.2009

    • Author(s)
      Adachi, M., Ohhara, T., Kurihara, K., Tamada, T., Honjo, E., Okazaki, N., Arai, S., Shoyama, Y., Kimura, K., Matsumura, H., Sugiyama, S., Adachi, H., Takano, K., Mori, Y., Hidaka, K., Kimura, T., Hayashi, Y., Kiso, Y., Kuroki, R.
    • Journal Title

      Proc Natl Acad Sci USA. 106

      Pages: 4641-4646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond.2009

    • Author(s)
      Tamada, T., Kinoshita, T., Kurihara, K., Adachi, M., Ohhara, T., Imai, K., Kuroki, R., Tada, T.
    • Journal Title

      J Am Chem Soc. 131

      Pages: 11033-11040

    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.2009

    • Author(s)
      Hidaka, K., Kimura, T., Abdel-Rahman, H.M., Nguyen, J.T., McDaniel, K.F., Kohlbrenner, W.E., Molla, A., Adachi, M., Tamada, T., Kuroki, R., Katsuki, N., Tanaka, Y., Matsumoto, H., Wang, J., Hayashi, Y., Kempf, D.J., Kiso, Y.
    • Journal Title

      J Med Chem. 52(23)

      Pages: 7604-7617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272.2008

    • Author(s)
      Matsumura, H., Adachi, M., Sugiyama, S., Okada, S., Yamakami, M., Tamada, T., Hidaka, K., Hayashi, Y., Kimura, T., Kiso, Y., Kitatani, T., Maki, S., Yoshikawa, H.Y., Adachi, H., Takano, K., Murakami, S., Inoue, T., Kuroki, R., Mori, Y.
    • Journal Title

      Acta Crystallogr Sect F64

      Pages: 1003-1006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Mutagenesis of the crystal contact of acidic fibroblast growth factor.2008

    • Author(s)
      Honjo, E., Tamada, T., Adachi, M., Kuroki, R., Meher, A., Blaber, M.
    • Journal Title

      J.Synchrotron Radiat. 15

      Pages: 285-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272.2008

    • Author(s)
      Matsumura, H., Adachi, M., Sugiyama, S., Okada, S., Yamakami, M., Tamada, T., Hidaka, K., Hayashi, Y., Kimura, T., Kiso, Y., Kitatani, T., Maki, S., Yoshikawa, H.Y., Adachi, H., Takano, K., Murakami, S., Inoue, T., Kuroki, R., Mori, Y.
    • Journal Title

      Acta Crystallogr Sect F64

      Pages: 1003-1006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Journal Article] Mutagenesis of the crystal contact of acidic fibroblast growth factor.2008

    • Author(s)
      Honjo, E., Tamada, T., Adachi, M., Kuroki, R., Meher, A., Blaber, M.
    • Journal Title

      J. Synchrotron Radiat. 15

      Pages: 285-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Journal Article] Evaluation of solubility and emulsifying property of soybean proglycinin and rapeseed procruciferin in relation to structure by protein engineering.2005

    • Author(s)
      Tandang, M.R.G., Atsuta, N., Adachi, M., Maruyama, N., UtsumiI, S.
    • Journal Title

      J.Agric.Food Chem. 53

      Pages: 8736-8744

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Structure-function relationship of soybean proglycinins at subunit level.2005

    • Author(s)
      Prak, K., Nakatani, K., Katsube-Tanaka, T., Adachi, M., Murayama, N., Utsumi, S.
    • Journal Title

      J.Agric.Food Chem. 53

      Pages: 3650-3657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] The effects of designed sulfhydryl groups and disulfide bonds into soybean proglycinin on its structural stability and heat-induced gelation.2004

    • Author(s)
      M.Adachi
    • Journal Title

      J. Agric. Food Chem. 52

      Pages: 5717-5723

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] The effects of designed sulfhydryl groups and disulfide bonds into soybean proglycinin on its structural stability and heat-induced gelation.2004

    • Author(s)
      Adachi, M., Ho, C., Utsumi, S.
    • Journal Title

      J.Agric.Food Chem. 52

      Pages: 5717-5723

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Cloning and expression of rapeseed procruciferin in Escherichia coli and crystallization of the purified recombinant protein.2004

    • Author(s)
      Tandang, M.R.G., Adachi, M., Utsumi, S.
    • Journal Title

      Biotechnol.Lett. 26

      Pages: 385-391

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] The effects of designed sulfhydryl groups and disulfide bonds into soybean proglycinin on its structural stability and heat-induced gelation.2004

    • Author(s)
      M.Adachi
    • Journal Title

      J.Agric.Food Chem. 52

      Pages: 5717-5723

    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] 8S globulin of mungbean [Vigna radiata (L.) Wilczek] : Cloning and characterization of its cDNA isoforms, expression in Escherichia coli, purification, and crystallization of the major recombinant 8S isoform.2004

    • Author(s)
      Bernardo, A.E.N., Garcia, R.N., Adachi, M, Angeles, J.G.C., Kaga, A., Ishimoto, M., Utsumi, S., Tecson-Mendoza, E.M.
    • Journal Title

      J.Agiric.Food Chem. 52

      Pages: 2552-2560

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Crystal structure and structural stabilities of the disulfide-deficient soybean proglycinin mutants C12G and C88S2003

    • Author(s)
      M.Adachi
    • Journal Title

      Journal of Agricultural and Food Chemistry 51

      Pages: 4633-4639

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Crystal structure of soybean IIS globulin : Glycinin A3B4 homohexamer2003

    • Author(s)
      M.Adachi
    • Journal Title

      Proceeding of the National Academy of Sciences of the United States of America 100

      Pages: 7395-7400

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Crystal structures and structural stabilities of the disulfide-deficient soybean proglycinin mutants C12G and C88S.2003

    • Author(s)
      Adachi, M., Okuda, E., Kaneda, Y., Hadhimoto, A., Shutov, A.D., Becker, C., Muntz, K., Utsumi, S.
    • Journal Title

      J.Agric.Food Chem. 51

      Pages: 4633-4639

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Journal Article] Crystal structure of soybean 11S globulin : Glycinin A3B4 homohexamer.2003

    • Author(s)
      Adachi, M., Kanamori, J., Masuda, T., Yagisaki, K., Kitamura, K., Mikami, B., Utsumi, S.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 7395-7400

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380092
  • [Presentation] 重水素化医薬品の代謝におけるCYP2C9と薬物との相互作用及びKIEの評価2024

    • Author(s)
      西尾 彩花、山副 紗知、小林 文音、髙橋 知里、德川 宗成、澤間 善成、奈良岡 あすか、中 寛史、安達 基泰、前川 京子
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PLANNED-20H05741
  • [Presentation] 等温滴定型カロリメトリーを用いた薬物代謝酵素P450と薬物との相互作用測定法の構築2023

    • Author(s)
      井川 佑美 , 若松 三友紀 , 高橋 知里 , 安達 基泰 , 前川 京子
    • Organizer
      日本薬学会第143回年会
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] 乳酸菌Weissella viridescens JCM1174の新規2ドメイン型アミノ酸ラセマーゼの大腸菌での発現系の構築と酵素科学的特性の解明2023

    • Author(s)
      大島 尚哉 , 安達 基泰 , 加藤 志郎 , 老川 典夫
    • Organizer
      日本農芸化学会2023年度大会
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] ENZYME ACTIVITY AND PEPTIDOMIMETIC INHIBITOR AFFINITY FOR DRUG-RESISTANT MUTANT INTERMEDIATES OF HIV PROTEASE2023

    • Author(s)
      Koushi Hidaka and Motoyasu Adachi
    • Organizer
      The Japanese Peptide Society
    • Data Source
      KAKENHI-PROJECT-21K05301
  • [Presentation] 等温滴定型カロリメトリーを用いた薬物代謝酵素 P450と薬物との相互作用測定法の構築2023

    • Author(s)
      井川佑美、若松三友紀 、大平真理 、高橋知里1、安達基泰 、前川京子
    • Organizer
      日本薬学会第143年会 札幌
    • Data Source
      KAKENHI-PROJECT-18K06613
  • [Presentation] Impact of Substrate Deuteration on Warfarin Metabolism Involving CYP2C92023

    • Author(s)
      Chisato Takahashi, Ayane Kobayashi, Miyuki Wakamatsu, Kaede Inoue, Yuki Kitajima, Motoyasu Adachi, Yoshinari Sawama, Keiko Maekawa
    • Organizer
      2023年ICCP450/JSSX国際合同大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05741
  • [Presentation] 乳酸菌Weissella viridescens JCM1174の新規2ドメイン型アミノ酸ラセマーゼの発見と基礎的性質2021

    • Author(s)
      大島 尚哉、安達 基泰、加藤 志郎、山中 一也、老川 典夫
    • Organizer
      第16回D-アミノ酸学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] Recent Activity of D-lab in MLF, J-PARC2021

    • Author(s)
      Adachi Motoyasu
    • Organizer
      DEUNET Virtual Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] Biophysical Approach to Elucidate the Basis of Losartan Binding to Drug Metabolizing Enzyme cytochrome P450 2C92021

    • Author(s)
      Chisato Takahashi, Natsumi Kita, Yukiho Minami, Motoyasu Adachi, Keiko Maekawa
    • Organizer
      日本薬物動態学会 第36回年会 高崎
    • Data Source
      KAKENHI-PROJECT-18K06613
  • [Presentation] タンパク質の中性子結晶構造解析と重水素2021

    • Author(s)
      安達 基泰
    • Organizer
      重水素化学研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] 薬物代謝酵素CYP2C9の構造活性相関研究のための大腸菌における発現系 の改良に関する研究2020

    • Author(s)
      堀田 美翔、南 幸穂、北 奈都水、瀨古 寿々菜、大石 真理子、髙橋 知里、安達 基泰、前川 京 子
    • Organizer
      日本薬学会第140 年会
    • Data Source
      KAKENHI-PROJECT-18K06613
  • [Presentation] 中性子による最近の構造解析研究Ⅱ2020

    • Author(s)
      安達 基泰
    • Organizer
      重水素化薬剤研究会2020横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Photovoltaic properties of solar cell sensitized with light-harvesting protein complex for potential energy harvesting devise2020

    • Author(s)
      田村浩司,清水瑠美,安達基泰,田口富嗣,大場弘則
    • Organizer
      2020年web光化学討論会
    • Data Source
      KAKENHI-PROJECT-18K05308
  • [Presentation] Recent Activity of D-lab in MLF, J-PARC2020

    • Author(s)
      Motoyasu Adachi
    • Organizer
      DEUNET Virtual meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03377
  • [Presentation] 生物理学的手法を用いた薬物代謝酵素CYP2C9の 基質結合様式の解明2019

    • Author(s)
      髙橋知里, 桂木麻衣, 木谷理紗 , 堀田美翔, 安達基泰, 前川京子
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K06613
  • [Presentation] 量子効果と量子ダイナミクス解析によるタンパク質研究の パラダイムシフト2019

    • Author(s)
      安達 基泰
    • Organizer
      次世代放射光超高分解能RIXS ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] タンパク質の中性子結晶構造解析とその未来への展望:ヒト由来プロテインキナーゼCK2の解析から2019

    • Author(s)
      安達 基泰
    • Organizer
      バイオサイエンスセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] A NOVEL PYRIDOXAL 5′-PHOSPHATE-DEPENDENT HISTIDINE RACEMASE FROM LEUCONOSTOC MESENTEROIDES SUBSP. SAKE NBRC 102480: DISCOVERY AND STRUCTURAL CHARACTERIZATION2019

    • Author(s)
      Motoyasu Adachi, Rumi Shimizu, Shiro Kato, Tadao Oikawa
    • Organizer
      The 4th International Conference of D-Amino Acid Research (IDAR2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Crystal Structure of CYP2C9*2 Genetic Variant in Complex with an Angiotensin II Receptor Blocker Drug Losartan2019

    • Author(s)
      Chisato Takahashi, Natsumi Kita, Yukiho Minami, Mika Horita, Mai Katsuragi, Risako Kitani, Motoyasu Adachi, Keiko Maekawa
    • Organizer
      日本薬物動態学会 第34回年会 つくば
    • Data Source
      KAKENHI-PROJECT-18K06613
  • [Presentation] ヒト由来プロテインキナーゼCK2の中性子結晶構造解析2019

    • Author(s)
      安達 基泰
    • Organizer
      CBI学会2019年大会 (第20回FMO研究会 生命現象を量子構造生物学で解き明かす), 情報計算化学生物学会(CBI学会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Neutron crystal structure analysis of human casein kinase II (CK2)2019

    • Author(s)
      Motoyasu Adachi
    • Organizer
      27th International Society of Heterocyclic Chemistry (ISHC) Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Conformation analysis of hydrogen atoms around ligand-binding pocket based on quantum chemical calculation2019

    • Author(s)
      Chiduru Watanabe, Kaori Fukuzawa, Yoshio Okiyama, Motoyasu Adachi, Shigenori Tanaka, Teruki Honma
    • Organizer
      CBI学会2019年大会, 情報計算化学生物学会(CBI学会)
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] First neutron stuructural analaysis of human casein kinase II2018

    • Author(s)
      Motoyasu Adachi, Chie Shibazaki, Rumi Shimizu, Shigeki Arai, Andreas Ostermann, Tobias E. Schrader
    • Organizer
      The 31st European Crystallographic Meeting (ECM31)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Long hydrogen bonding network responsible for catalytic activity of human casein kinase II2018

    • Author(s)
      Chie Shibazaki, Rumi Shimizu, Shigeki Arai, Motoyasu Adachi
    • Organizer
      3rd International Symposium of Quantum Beam Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] 非凍結結晶を用いたβ-アミラーゼ(E380A)と基質との複合体のpH変化の解析2018

    • Author(s)
      三上文三、安達基泰、姜有那、水谷公彦
    • Organizer
      日本農芸化学会2018年度大会
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] ヒトカゼインキナーゼIIの触媒活性に係わる新たな水素結合ネットワークの発見2018

    • Author(s)
      柴崎千枝、清水瑠美、新井栄揮、安達基泰、黒木良太
    • Organizer
      2017年度量子ビームサイエンスフェスタ (第9回MLFシンポジウム・第35回PFシンポジウム)
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Perdeuteration and protein neutron crystallography (for beginners)2017

    • Author(s)
      Motoyasu Adachi
    • Organizer
      J-PARC WORKSHOP Deuterated Materials Enhancing Neutron Science for Structure Function Applications
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] HIV-1 プロテーゼの中性子構造解析2017

    • Author(s)
      安達基泰
    • Organizer
      第8回東海地区中性子生命科学検討会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0063
  • [Presentation] Crystal Structures of CYP2C9, CYP2C9*3 and CYP2C9*30 in Complex with Multiple Losartan Molecules Reveal a Peripheral Binding Site and Alternate Active Site Orientations.2016

    • Author(s)
      Maekawa K, Adachi M, Matsuzawa Y, Kuroki R, Saito Y, Shah M
    • Organizer
      The 21st International Symposium on Microsomes and Drug Oxidations (MDO2016)
    • Place of Presentation
      UC Davis Conference Center, Davis, California, USA
    • Year and Date
      2016-10-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Presentation] HIVプロテアーゼの薬剤耐性機構解明に向けた中性子解析2016

    • Author(s)
      安達 基泰
    • Organizer
      中性子生命科学研究会
    • Place of Presentation
      いばらき量子ビーム研究センター
    • Year and Date
      2016-05-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460055
  • [Presentation] ヒト由来薬物代謝酵素CYP2C9の一塩基置換体(*3および*30)と抗高血圧薬ロサルタンとの複合体のX線結晶構造解析2015

    • Author(s)
      安達 基泰, 黒木 良太、前川 京子, 松澤 由美子, 斎藤 嘉朗
    • Organizer
      BMB2015(第 38回日本分子生物学会年会、第 88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Presentation] Purification of cytochrome P450 2C9.1, 2C9.3 and 2C9.30 expressed in E. coli and their activities toward arachidonic acid in vitro2015

    • Author(s)
      Keiko Maekawa, Yumiko Matsuzawa, Motoyasu Adachi, Ryota Kuroki, Yoshiro Saito
    • Organizer
      19th International Conference on Cytochrome P450
    • Place of Presentation
      National Olympics Memorial Youth Center, Shibuya-ku, Tokyo
    • Year and Date
      2015-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Presentation] 不活性型一本鎖HIV-1プロテアーゼと阻害剤KNI-272との複合体のX線結晶構造解析2013

    • Author(s)
      安達基泰
    • Organizer
      第12回日本蛋白質科学会
    • Place of Presentation
      とりぎん文化会館(鳥取市)
    • Year and Date
      2013-06-09
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] 不活性型一本鎖HIV-1プロテアーゼと阻害剤KNI-272との複合体のX線結晶構造解析2013

    • Author(s)
      安達 基泰, 清水 瑠美, 黒木 良太, 森谷圭介, 城所俊一, 日高 興士, 津田 裕子, 木曽 良明
    • Organizer
      第12回日本蛋白質科学会
    • Place of Presentation
      とりぎん文化会館(鳥取)
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] モルヒネの代謝反応を触媒する組換え型パーオキシダーゼの調製2012

    • Author(s)
      清水 瑠美、安達 基泰、黒木 良太、山下 未知、森元 聡
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590149
  • [Presentation] X-Ray Structure Analysis of the Single-Chain Derivative of HIV-1 Protease2012

    • Author(s)
      Motoyasu Adachi and Ryota Kuroki
    • Organizer
      The 12th Japan China Korea Joint Symposium on Enzyme Engineering
    • Place of Presentation
      金沢全日空ホテル(石川県金沢市)
    • Data Source
      KAKENHI-PROJECT-22390010
  • [Presentation] モルヒネの代謝反応を触媒する組換え型パーオキシダーゼの調製2012

    • Author(s)
      清水瑠美, 安達基泰, 黒木良太, 山下未知, 森元聡
    • Organizer
      日本蛋白質科学会
    • Year and Date
      2012-06-20
    • Data Source
      KAKENHI-PROJECT-23590149
  • [Presentation]2012

    • Author(s)
      Motoyasu Adachi and Ryota Kuroki
    • Organizer
      The 12th Japan China Korea Joint Symposium on Enzyme Engineering
    • Place of Presentation
      金沢全日空ホテル(金沢市)
    • Year and Date
      2012-05-29
    • Data Source
      KAKENHI-PROJECT-22390010
  • [Presentation] X-Ray Structure Analysis of the Single-Chain Derivatives of HIV-1 Protease in Complex with Inhibitor2012

    • Author(s)
      安達基泰
    • Organizer
      Asian Crystallographic Association (AsCA12)
    • Place of Presentation
      アデレードコンベンションセンター(オーストラリア,アデレード)
    • Year and Date
      2012-12-03
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] 1本鎖化HIVPRの阻害剤との複合体のX線結晶構造解析2012

    • Author(s)
      安達基泰
    • Organizer
      第12回日中韓酵素工学会議
    • Place of Presentation
      金沢エクセルホテル東急(石川県金沢市)
    • Year and Date
      2012-05-29
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] SS結合の導入によるHIV-1プロテアーゼの一本鎖化2012

    • Author(s)
      安達基泰
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2012-06-21
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] HIV-1プロテアーゼの一本鎖化と阻害剤複合体のX線結晶構造解析2011

    • Author(s)
      安達基泰
    • Organizer
      第10回日本蛋白質科学会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] HIV-1プロテアーゼの一本鎖化と阻害剤複合体のX 線結晶構造解析2011

    • Author(s)
      安達基泰
    • Organizer
      日本蛋白質科学会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] 薬剤耐性A17型HIV-1プロテアーゼと阻害剤複合体のX線結晶構造解析2010

    • Author(s)
      安達基泰(代表者)
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] 薬剤耐性A17型HIV-1プロテアーゼと阻害剤複合体のX線結晶構造解析2010

    • Author(s)
      安達基泰, 他
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-22390010
  • [Presentation] Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by Neutron Crystallography2010

    • Author(s)
      安達基泰(代表者)
    • Organizer
      The 5th International Peptide Symposium
    • Place of Presentation
      京都国際会議場(京都市)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] 放射光と中性子を相補的に用いたヒト免疫不全ウイルスプロテアーゼ阻害剤の立体構造解析2010

    • Author(s)
      安達基泰(代表者)
    • Organizer
      酵素工学研究会第64回講演会
    • Place of Presentation
      東京大学「山上会館」(東京都文京区)
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] Structure of HIV-1 Protease in Complex with Inhibitor KNI-272 Determined by Neutron Crystallography2010

    • Author(s)
      安達基泰(代表者)
    • Organizer
      11th China-Japan-Korean Joint Symposium on Enzyme Engineering[第11回日中韓酵素工学会議]
    • Place of Presentation
      Green Land Hotel(中国成都)
    • Year and Date
      2010-11-07
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] HIV-1プロテアーゼの中性子結晶構造解析2009

    • Author(s)
      安達基泰(代表者)
    • Organizer
      第9回日本蛋白質科学会年会
    • Place of Presentation
      熊本全日空ホテルニュースカイ(熊本市)
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] Neutron Crystallography for Investigation of Catalytic Mechanism of HIV-1 protease2009

    • Author(s)
      安達基泰 黒木良太, 他
    • Organizer
      ATI国際フォーラム
    • Place of Presentation
      テクノ交流間リコッティ(茨城県東海村)
    • Year and Date
      2009-03-10
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Presentation] Neutron Crystallography for Investigation of Catalytic Mechanism of HIV-1 Protease2009

    • Author(s)
      安達基泰(代表者)
    • Organizer
      ATI International Forum 2009 "Protein Structure Determination and Applications"
    • Place of Presentation
      原子力機構・テクノ交流館リコッティー(茨城県東海村)
    • Year and Date
      2009-03-10
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] Structure of HIV-1 Protease in Complex with Inhibitor KNI-272 Determined by Neutron Crystallography2009

    • Author(s)
      安達基泰(代表者)
    • Organizer
      Joint Conference of the Asian Crystallographic Association & Chinese Crystallography Society
    • Place of Presentation
      Jingyi Hotel(中国北京)
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] HIV-1プロテアーゼの中性子結晶構造解析2008

    • Author(s)
      安達基泰
    • Organizer
      日本中性子科学会第8回年会
    • Place of Presentation
      名古屋大学東山キャンパス豊田講堂(名古屋市)
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] HIV-1プロテアーゼの中性子結晶構造解析2008

    • Author(s)
      安達基泰
    • Organizer
      日本中性子科学会年会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19370046
  • [Presentation] HIV-1プロテアーゼとKNI-272との複合体の中性子構造解析2008

    • Author(s)
      安達基泰(代表者)
    • Organizer
      International Symposium on Integrated Medicinal Science-On the basis of traditional medicine to biomolecular system-
    • Place of Presentation
      京都薬科大学愛学館(京都市)
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-20790046
  • [Presentation] X線結晶回折法によるヒト由来薬物代謝酵素CYP2C9および一塩基置換体(*30)と抗高血圧薬ロサルタンの相互作用解析

    • Author(s)
      安達 基泰, 前川 京子, 松澤 由美子, 斎藤 嘉朗, 黒木 良太
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Presentation] Purification of cytochrome P450 2C9.1, 2C9.3 and 2C9.30 expressed in E. coli and their activities toward arachidonic acid in vitro

    • Author(s)
      Keiko Maekawa, Yumiko Matsuzawa, Motoyasu Adachi, Ryota Kuroki and Yoshiro Saito
    • Organizer
      19th International Conference on Cytochrome P450
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-06-12 – 2015-06-15
    • Data Source
      KAKENHI-PROJECT-25293128
  • [Presentation] 1本鎖化HIVPRの阻害剤との複合体のX線結晶構造解析

    • Author(s)
      安達基泰
    • Organizer
      第12回日中韓酵素工学会議
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-23770129
  • [Presentation] SS結合の導入によるHIV-1プロテアーゼの一本鎖化

    • Author(s)
      安達基泰
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      金沢エクセルホテル東急(石川県)
    • Data Source
      KAKENHI-PROJECT-23770129
  • 1.  MARUYAMA Nobuyuki (90303908)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 2.  TAMADA Taro (50391248)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 3.  UTSUMI Shigeru (40111976)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 7 results
  • 4.  MAEKAWA Keiko (70270626)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 13 results
  • 5.  KURIHARA Kazuo (50354890)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 6.  KIDOKORO Shun-ichi (80195320)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KUROKI Ryota (30391246)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 8.  OHHARA Takashi (60391249)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  SAITO Yoshiro (50215571)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 10.  MORIMOTO Satoshi (60191045)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  TAMURA Koji (10354820)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  老川 典夫 (80233005)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  岡島 俊英 (10247968)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  SAITO Minoru (60196011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  UMINO Hisao (20399421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OKAZAKI Nobuo (60391900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  IZUHARA Kenji (00270463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKEGAWA Kaoru (50197282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  Yao Min (40311518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  Kato Koji (30452428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HIDAKA Koushi (30445960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  佐々木 香織 (90464388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  谷内田 真一 (20359920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  竹中 康之 (20273518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  木下 誉富 (90405340)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  高橋 知里 (70833680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  村川 武志 (90445990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  鈴木 守 (40280507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  SHIMIZU Rumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SHIBAZAKI Chie
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KAGOTANI Yuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  HIROTSUKA Motohiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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