Nakayama Keiko 中山啓子

… Alternative Names

NAKAYAMA Keiko 中山啓子

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Researcher Number	60294972
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東北大学, 医学系研究科, 教授 2015 – 2016: 東北大学, 大学院医学系研究科, 教授 2014 – 2016: 東北大学, 医学(系)研究科(研究院), 教授 2014: 東北大学, 医学系研究科, 教授 2011: Tohoku University, 医学(系)研究科(研究院), 教授 … More 2007 – 2010: Tohoku University, Tohoku University, Graduate School of Medicine, Professor 2007: Tohoku University, 大学院・医学研究科, 教授 2006: 東北大学, 大学院医学系研究科, 教授 2002 – 2005: Tohoku Univ. Faculty of Med., Prof., 大学院・医学系研究科, 教授 2003: 東北大学, 大学院・医学研究科, 教授 1998 – 2002: Medical Institute of Bioregulation, Kyushu University, Professor, 生体防御医学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Cell biology / General medical chemistry / Basic Section 50010:Tumor biology-related / Basic Section 43050:Genome biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Molecular biology / General physiology / Molecular biology / General anatomy (including histology/embryology) … More / Tumor biology / Developmental biology / Developmental biology / Cell biology … More Except Principal Investigator Biological Sciences / Basic Section 55020:Digestive surgery-related / Neurochemistry/Neuropharmacology / Cell biology / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Biological Sciences / Genome biology / Tumor biology / General physiology / Immunology / Functional biochemistry / Neurology / Experimental pathology / Functional biochemistry / Cell biology / Molecular biology / Thoracic surgery / Digestive surgery / General medical chemistry Less
Keywords	Principal Investigator ノックアウトマウス / Geminin / c-Myc / Cdc4 / Skp2 / サイクリンE / ユビキチン化 / ユビキチンリガーゼ / 細胞周期 / p27 … More / ES細胞 / 細胞増殖 / ユビキチン / F-boxタンパク質 / β-TrCP2 / Skp1 / SCF複合体 / エピゲノム / F-box protein / knock-out mouse / Cul-1 / CRISPR/Cas9 / 乳癌細胞株 / ヒストン修飾 / 転写制御 / 分化 / 発生・分化 / 発現制御 / Nocth / Cdt1 / 中心体 / 蛋白分解 / 腫瘍環境 / splicing / Fibulin 2 / 膵臓癌 / 抗癌剤 / SETD5 / ヒストンH3 Lys27メチル化 / エピゲノム制御 / トランスオミクス解析 / 細胞老化 / RASシグナル / シグナル伝達経路 / Myc遺伝子 / TGF-β刺激 / 遺伝子増幅 / DRB / H3K36me3 / H3K27me3 / 修飾酵素 / RNAポリメラーゼ / MLL2 / エピゲム / 腫瘍形成能 / 超並列シークエンス解析 / CRISPR/Cas9システム / ゲノム編集 / 免疫不全マウス / 次世代シークエンサー / 腫瘍形成 / circadian rhythm / knockout mouse / Ubiquitin / in situ hybridization / 血管リモデリング / 概日リズム / affinity chromatography / ubiquitin ligase / プロテオーム解析 / プロテオーム / 蛍光色素標識 / アフィニティークロマトグラフィー / Ubiquitin Ligase / F-boxタンパク / 3T3-L1 / メチル化酵素 / インスリン分泌細胞 / Bリンパ球 / リンパ球 / ChIPシークエンス / Ｂリンパ球 / in vivoモニタリング / 蛍光色素 / タンパク質相互作用 / β-TcP2 / Fbxw7 / β-TrCP1 / セントリンII / 蛍光タンパク質 / histoneH3.1 / レンチウィルス / 蛍光ラベル / 細胞内小器官 / 複製ライセンシング / DNA複製 / β-catenin / Tcf-LacZトランスジェニックマウス / たんぱく質 / Notch / Fbw7 / コンディショナルノックアウト / HDAC / EID / C2C12 / p300 / EID4 / EID2 / 蛍光顕微鏡 / 前複製複合体 / Mitosis / DNA合成 / 過剰複製 / Notch-4 / ライブラリー / トランスジェニックマウス / リボザイム / ノックインマウス / C / APC / Cyclin E / 血管形成異常 / Notch4 / Fbw1 / 中心体過剰複製 / 染色体倍数性異常 / ユビキチシリガーゼ / Cul1 / マウスCu1-1 / Cdc53 / マウスCul1 / サイクリン / プロセシング / ユピキチン化 / サイクリン依存性キナーゼ阻害分子 … More Except Principal Investigator 細胞周期 / ユビキチン化 / ユビキチン / p27 / UFD2 / MJD / VCP / プロテアソーム / 蛋白分解 / 幹細胞 / エピジェネティクス / ubiquitination / ノックアウトマウス / ユビキチンリガーゼ / 転写 / p57 / cell cycle / サイレンシング / PKC-δ / プロテオミクス / Mad / Nedd-4 / Myc / ポリグルタミン病 / 神経変性疾患 / proteasome / シグナル伝達 / PKCδ / ユビキチン様タンパク質 / 翻訳後修飾 / β-catenin / IκBα / SCF / サイクリン依存性キナーゼ阻害分子 / collagen XVII / 膵癌 / COL17A1 / collagen XⅦ / リプログラミング / がん / 遺伝子発現調節機構 / 代謝 / マイクロエクソン / 大腸癌 / ポリコーム / CRISPR/Cas9 / エンハンサー / ヒストン修飾 / スクリーニング / shRNA / RAS / 再生医学 / 再生医科学 / GO phase / CDK inhibitor / affinity chromatography / 蛋白質 / アフィニティークロマトグラフィー / GO期 / CDKインヒビター / Runx family / gene silencing / CD4 gene / epigenetics / silencing / Runx / T細胞分化 / CD4 / Runxファミリィー / Runxファミリー / CD4遺伝子 / エピジェネティックス / Knockout mouse / Posttranslational modification / Mass analysis / Phosphorylation / Signal transduction / Proteomics / Embryonic and genetic engineering / 質量分析 / リン酸化 / 発生工学 / U-box protein / Quality control / Neurodegenerative disease / Ubiquitin ligase / ubiquitin / U-ボックス / Skp2 / カテニン / NF-κB / U-ボックスタンパク質 / 品質管理 / chimeric-protein / Ubiquitiylation / プロテアゾームインヒビター / Nedd4 / Max / キメラタンパク / Ubiquitylation / polyglutamine Disease / VPC / MJD1 / polyglutamine disease / Machado-Joseph Disease / proteolysis / neurodegenerative disease / inclusion body / ユビキチン鎖伸長因子(E4) / UFD2a / マシャド・ジョセフ病 / Machado-Joseph病 / 蛋白質分解 / 封入体 / cyclin-dependent kinase / lung cancer / p27ィイD1Kip1ィエD1 / プロセッシング / ユビキチン-プロテアソーム / サイクリン依存性キナーゼ / 肺がん / p27^<Kip1> / colon cancer / F-box蛋白質 / 大腸がん / β-カテニン / proliferation control / B cell / singal transduction / knockout mice / apoptosis / ICE様プロテアーゼ / ES細胞 / ジーンターゲティング / プロテインキナーゼC / 増殖制御 / B細胞 / アポトーシス / ＰＰＡＲ－γ / ユビチキン・プロテアソーム系 / 心臓大血管周術期腎保護 / 心臓大血管外科 / LXR-α / PPAR-γ / ユビキチン・プロテアソーム系 / 腎保護 / 腎虚血再灌流障害 / 遺伝子 / 胆管癌 / Fbw7 / 胆道癌 / Cvclin F / 細胞分裂 / 翻訳語修飾 / タンパク質 / pRB / 分化 / HDAC / EID-3 / EID-2 / EID-1 / たんぱく質分解 / KPC / タンパク質分解 / β-TrCP / FWD1 / Cul-1 / Skp1 / F-box蛋白 / タンパク分解 / Rum1 / 酵母 / Yeast three-hybrid法 / ユピキチン化 Less

Regulation of tumor progression by selective splicing of Fibulin 2 in the tumor environmentPrincipal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
幹細胞における時空間リプログラミングの機構解明と疾患との関わりの研究
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tokyo Medical and Dental University
  Kyushu University
膵癌術前治療耐性克服を目指したcollagen XVIIを標的とする新規治療開発
- Principal Investigator
  
  水間正道
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Function of SETD5 in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Nakayama Keiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tohoku University
Identification of novel microexon involved in the regulation of colorectal cancer
- Principal Investigator
  
  Hideaki Karasawa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Elucidation of the signaling pathways that induce gene amplificationPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Tohoku University
Investigation for mechanisms underlying cell cycle regulation and metabolism in stem cells
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
細胞老化へ向かう代謝アダプテーションのエピゲノムからの探索Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tohoku University
Elucidation of the mechanism of transcription elongation rate control by histone codePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Verification of genomic diversity required for tumorigenesisPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University
Verification of genomic diversity required for tumorigenesisPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA KEIKO
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tohoku University
Genome wide analysis of epigenetic regulation of enhancer activity via H3K27 modifications
- Principal Investigator
  
  HOSOGANE Masaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Tohoku University
Elucidation of transcriptional regulation by histone modification patternPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Comprehensive screening of histone modifying enzymePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tohoku University
Molecular mechanism of oncogenic RAS-induced gene silencing
- Principal Investigator
  
  Funayama Ryo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Integrative study for functional analyses of stem cell maintenance factors and visualization of stem cells
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  General physiology
- Research Institution
  Kyushu University
Functional analysis and clinical application of the Ubiquitin - Proteasome pathway in the process of renal ischemia reperfusion injury.
- Principal Investigator
  
  MOTOYOSHI NAOTAKA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Tohoku University
RAS活性化による転写制御ー染色体領域に注目したアプローチによる解析Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Analysis of carcinogenic mechanism of biliary tract cancer from the protein control by ubiquitin ligase Fbw7
- Principal Investigator
  
  KATAYOSE Yu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
In vivoタンパク質複合体形成モニタリングの試みPrincipal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Developmental biology
- Research Institution
  Tohoku University
Molecular and temporal-spatial regulation of ubiquitin ligase , F-box proteinPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
Analysis of M phase-regulation by GdX
- Principal Investigator
  
  ISHIDA Noriko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
発生におけるタンパク質分解制御機構とその意義の解明Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
The turning point from cell proliferation to cell differentiationPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
細胞周期と初期発生に関わる分子群の新規解析法の開発Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
ユビキチンリガーゼCdc4/Fbw7変異にともなう組織特異的細胞増殖機構の解明Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Search for physiological substrates and functional analysis of F-box protein β-TrCP in vivoPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
Analysis of G0 phase-specific large complex including p27
- Principal Investigator
  
  ISHIDA Noriko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
発がんにおけるユビキチンリガーゼCdc4/Fbw7基質分子の役割Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
タンパク質の安定性に関わる新規翻訳後修飾、Gdx化システムの分子機構の解明
- Principal Investigator
  
  石田典子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
新規分化抑制因子EIDによる哺乳類幹細胞の未分化性維持機構の解明Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
サイクリンEとMycの分解に関与するユビキチンリガーゼCdc4の発癌に果たす役割Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Gemininノックアウトマウスを用いた複製開始機構の解析Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
分化と増殖の転換の分子機構の解明
- Principal Investigator
  
  三宅智
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Functional Analysis of Proteins regulated by Ubiquitin LigasePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
サイクリンEのユビキチンリガーゼCdc4が細胞周期進行に果たす役割Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
プロテアソームへのユビキチン化基質のターゲッテング機構の解析
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Analysis of the PKC-δ Signaling Pathway by Proteomics with Embryonic and Genetic Engeneering
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  KYUSHU UNIVERSITY
Study of molecular mechanisms of CD4 silencing and role s of Runx proteins during lymphocyte development
- Principal Investigator
  
  TANIUCHI Ichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  RIKEN (Institute of Physical and Chemical Research)
  Kyushu University
2種類のサイクリンE分解機構の細胞周期進行における役割Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
マウスGemininの発生工学的手法を用いた機能解析Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
  Kyushu University
プロテアソームへのユビキチン化基質のターゲッテング機構の解析
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
リボザイムを用いた組織特異的ノックアウトマウス作製法の開発Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Developmental biology
- Research Institution
  Tohoku University
  Kyushu University
中心体過剰複製と染色体倍数性異常の発がんにおける役割の研究Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
New clearance system of abnormal protein in Polyglutammine disease
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
New cancer therapy by degradation of specific proteins
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
Establishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteinsEstablishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteins
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Cyclin E過剰蓄積とp27の欠損を伴うマウスを用いた発がん機構の研究Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Functional analysis of ubiquitin ligase by knock-out misePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERSITY
細胞周期制御因子の分解機構の解明とノックアウトマウスを用いた発がん研究Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
サイクリン依存性キナーゼ阻害分子p27の分解因子の同定及び解析
- Principal Investigator
  
  小南欽一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
細胞周期調節分子の分解制御に関する研究-マウスSCF複合体の遺伝子クローニングと解析-
- Principal Investigator
  
  畠山鎮次
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Identification of the factors mediating ubiquitination of inclusion body in neurodegenerative diseases
- Principal Investigator
  
  NAKAYAMA Kei-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Medical Institute of Bioregulation, Kyushu University
サイクリン依存性キナーゼ阻害分子の分解機構の解明Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
細胞周期調節分子の分解制御に関する研究 - Yeast three-hybrid法の確立と応用 -
- Principal Investigator
  
  畠山鎮次
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
サイクリン分解関連酵素Cdc53(Cul-1)の単離とノックアウトマウスの作製Principal Investigator
- Principal Investigator
  
  中山啓子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyushu University
Identification and functional analysis of S phase promoting complex in mammalian cell growth
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  KYUSHU UNIVERSITY
Regulation of degradation of p27Kip1, one of CDK inhibitory protein, for cancer therapy
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  KYUSHU UNIVERSITY
Analysis of sinnalling pathway of apoptosis degradation using PKCδ gene-targeting mice
- Principal Investigator
  
  NAKAYAMA Kei-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University

[Book] 論文図表を読む作法2022
- Author(s)
  牛島　俊和、中山　敬一
- Total Pages
  288
- Publisher
  羊土社
- ISBN
  4758122601
- Data Source
  KAKENHI-PROJECT-18H05215
[Book] 実験医学2021年7月号2021
- Author(s)
  中山敬一
- Total Pages
  129
- Publisher
  羊土社
- ISBN
  9784758125451
- Data Source
  KAKENHI-PROJECT-18H05215
[Book] がん基盤生物学ー革新的シーズ育成に向けてー2013
- Author(s)
  武石昭一郎、中山敬一
- Total Pages
  8
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-25221303
[Book] 実験医学別冊「見つける、量る、可視化する！質量分析実験ガイド」2013
- Author(s)
  松本雅記、中山敬一
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25221303
[Book] 細胞周期細胞増殖の制御メカニズム2008
- Author(s)
  中山敬一、中山啓子(監訳)
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-20570175
[Book] キーワードで理解する細胞周期イラストマップ (中山敬一・編)2005
- Author(s)
  中山敬一
- Total Pages
  190
- Publisher
  羊土社 (東京)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Book] 決定版!プロテオーム解析マニュアル(礒辺俊明, 高橋信弘編)2004
- Author(s)
  松本雅記, 中山敬一
- Total Pages
  8
- Publisher
  羊土社(東京)
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Downregulation of <scp>ABCC3</scp> activates <scp>MAPK</scp> signaling through accumulation of deoxycholic acid in colorectal cancer cells2024
- Author(s)
  Sato Yukihiro、Kobayashi Minoru、Ohira Masahiro、Funayama Ryo、Maekawa Masamitsu、Karasawa Hideaki、Kashiwagi Ryosuke、Aoyama Yayoi、Mano Nariyasu、Ohnuma Shinobu、Unno Michiaki、Nakayama Keiko
- Journal Title
  
  Cancer Science
  
  Volume: Online ahead of print Issue: 6 Pages: 1778-1790
- DOI
  10.1111/cas.16132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15477, KAKENHI-PROJECT-21H02458
[Journal Article] p57Kip2 is an essential regulator of vitamin D receptor-dependent mechanisms.2023
- Author(s)
  Takahashi K, Amano H, Urano T, Li M, Oki M, Aoki K, Amizuka N, Nakayama KI, Nakayama K, Udagawa N, Higashi N.
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 2 Pages: e0276838-e0276838
- DOI
  10.1371/journal.pone.0276838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-22K06587, KAKENHI-PROJECT-19K07091, KAKENHI-PROJECT-22K10282, KAKENHI-PROJECT-23K06873, KAKENHI-PROJECT-23K21488, KAKENHI-PROJECT-18H05215
[Journal Article] IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of neural stem cells2023
- Author(s)
  Lozano-Urena A, Lazaro-Carot L, Jimenez-Villalba E, Montalban-Loro R, Mateos-White I, Duart-Abadia P, Martinez-Gurrea I, Nakayama KI, Farinas I, Kirstein M, Gil-Sanz C, Ferron SR.
- Journal Title
  
  Development
  
  Volume: 150 Issue: 1
- DOI
  10.1242/dev.200563
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] The ASC-1 complex promotes translation initiation by scanning ribosomes2023
- Author(s)
  Kito, Y., Matsumoto, A., Ichihara, K., Shiraishi, C., Tang, R., Hatano, A., Matsumoto, M., Han, P., Iwasaki, S., Nakayama, K. I.
- Journal Title
  
  EMBO Journal
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function2023
- Author(s)
  Shiraishi, C., Matsumoto, A., Ichihara, K., Yamamoto, T., Yokoyama, T., Mizoo, T., Hatano, A., Matsumoto, M., Tanaka, Y., Matsuura-Suzuki, E., Iwasaki, S., Matsushima, S., Tsutsui, H., Nakayama, K. I.
- Journal Title
  
  Nature Communications
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence After Chemotherapy of Intestinal Tumors2023
- Author(s)
  Oka Takeru、Higa Tsunaki、Sugahara Osamu、Koga Daisuke、Nakayama Shogo、Nakayama Keiichi I.
- Journal Title
  
  Cancer Research
  
  Volume: - Issue: 9 Pages: 1393-1409
- DOI
  10.1158/0008-5472.can-22-2578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation2023
- Author(s)
  11.Fujinuma S., Nakatsumi H., Shimizu H., Sugiyama S., Harada A., Goya T., Tanaka M., Kohjima M., Takahashi M., Izumi Y., Yagi M., Kang D., Kaneko M., Shigeta M., Bamba T., Ohkawa Y., Nakayama K.I.
- Journal Title
  
  Cell Reports
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment2023
- Author(s)
  Kashiwagi Ryosuke、Funayama Ryo、Aoki Shuichi、Matsui Aya、Klein Sebastian、Sato Yukihiro、Suzuki Tsubasa、Murakami Keigo、Inoue Koetsu、Iseki Masahiro、Masuda Kunihiro、Mizuma Masamichi、Naito Hisamichi、Duda Dan G.、Unno Michiaki、Nakayama Keiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 11 Pages: 4286-4298
- DOI
  10.1111/cas.15952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08816, KAKENHI-PROJECT-21K08725, KAKENHI-PROJECT-22K19520, KAKENHI-PLANNED-22H05063, KAKENHI-PROJECT-20H03435, KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-21H02996
[Journal Article] Molecular evolution of Keap1 was essential for adaptation of vertebrates to terrestrial life2023
- Author(s)
  Yumimoto K., Sugiyama S, Motomura S, Takahashi D., Nakayama K.I.
- Journal Title
  
  Science Advances
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Neurobehavioral characteristics of mice with SETD5 mutations as models of IDD23 and KBG syndromes.2023
- Author(s)
  Nakagawa T, Hattori S, Hosoi T, Nakayama K.
- Journal Title
  
  Front Genet.
  
  Volume: 13 Pages: 1022339-1022339
- DOI
  10.3389/fgene.2022.1022339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-21H02458
[Journal Article] A novel variant in the transmembrane 4 domain of ANO3 identified in a two-year-old girl with developmental delay and tremor2022
- Author(s)
  Aihara Yu、Shirota Matsuyuki、Kikuchi Atsuo、Katata Yu、Abe Yu、Niihori Tetsuya、Funayama Ryo、Nakayama Keiko、Aoki Yoko、Kure Shigeo
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 1 Pages: 51-54
- DOI
  10.1038/s10038-022-01082-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K12241, KAKENHI-PROJECT-21H02458
[Journal Article] SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones2022
- Author(s)
  Nakagawa T, Morohoshi A, Nagasawa Y, Nakagawa M, Hosogane M, Noda Y, Hosoi T, Nakayama K.
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 12 Pages: 110541-110541
- DOI
  10.1016/j.celrep.2022.110541
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-18KK0463, KAKENHI-PROJECT-21H02458
[Journal Article] Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism2022
- Author(s)
  Uematsu Saori、Ohno Satoshi、Tanaka Kaori Y.、Hatano Atsushi、Kokaji Toshiya、Ito Yuki、Kubota Hiroyuki、Hironaka Ken-ichi、Suzuki Yutaka、Matsumoto Masaki、Nakayama Keiichi I.、Hirayama Akiyoshi、Soga Tomoyoshi、Kuroda Shinya
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 2 Pages: 103787-103787
- DOI
  10.1016/j.isci.2022.103787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06577, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-17H06300
[Journal Article] Sex-Specific Differences in the Transcriptome of the Human Dorsolateral Prefrontal Cortex in Schizophrenia2022
- Author(s)
  Yu Zhiqian、Ueno Kazuko、Funayama Ryo、Sakai Mai、Nariai Naoki、Kojima Kaname、Kikuchi Yoshie、Li Xue、Ono Chiaki、Kanatani Junpei、Ono Jiro、Iwamoto Kazuya、Hashimoto Kenji、Kinoshita Kengo、Nakayama Keiko、Nagasaki Masao、Tomita Hiroaki
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 60 Issue: 2 Pages: 1083-1098
- DOI
  10.1007/s12035-022-03109-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-20K07962, KAKENHI-PLANNED-18H05430
[Journal Article] Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium2022
- Author(s)
  Higa Tsunaki、Okita Yasutaka、Matsumoto Akinobu、Nakayama Shogo、Oka Takeru、Sugahara Osamu、Koga Daisuke、Takeishi Shoichiro、Nakatsumi Hirokazu、Hosen Naoki、Robine Sylvie、Taketo Makoto M.、Sato Toshiro、Nakayama Keiichi I.
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1500-1500
- DOI
  10.1038/s41467-022-29165-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19J20466, KAKENHI-PROJECT-21K07155
[Journal Article] High levels of chromosomal instability facilitate the tumor growth and sphere formation2022
- Author(s)
  Iemura Kenji、Anzawa Hayato、Funayama Ryo、Iwakami Runa、Nakayama Keiko、Kinoshita Kengo、Tanaka Kozo
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 8 Pages: 2727-2737
- DOI
  10.1111/cas.15457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19283, KAKENHI-PUBLICLY-21H05738, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-23K23877
[Journal Article] Heterozygous calcyclin-binding protein/Siah1-interacting protein (CACYBP/SIP) gene pathogenic variant linked to a dominant family with paucity of interlobular bile duct2022
- Author(s)
  Kanno Miyako、Suzuki Mitsuyoshi、Tanikawa Ken、Numakura Chikahiko、Matsuzawa Shu-ichi、Niihori Tetsuya、Aoki Yoko、Matsubara Yoichi、Makino Satoshi、Tamiya Gen、Nakano Satoshi、Funayama Ryo、Shirota Matsuyuki、Nakayama Keiko、Mitsui Tetsuo、Hayasaka Kiyoshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 67 Issue: 7 Pages: 393-397
- DOI
  10.1038/s10038-022-01017-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02458, KAKENHI-PUBLICLY-21H00179
[Journal Article] Phosphorylation of PBX2, a novel downstream target of mTORC1, is determined by GSK3 and PP12022
- Author(s)
  Wada Reona、Fujinuma Shun、Nakatsumi Hirokazu、Matsumoto Masaki、Nakayama Keiichi I
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 2 Pages: 129-138
- DOI
  10.1093/jb/mvac094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07155, KAKENHI-PROJECT-22K19288, KAKENHI-PROJECT-20K21386, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-23K23870, KAKENHI-PROJECT-18H05215
[Journal Article] Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver2022
- Author(s)
  Huda Nazmul、Khambu Bilon、Liu Gang、Nakatsumi Hirokazu、Yan Shengmin、Chen Xiaoyun、Ma Michelle、Dong Zheng、Nakayama Keiichi I.、Yin Xiao-Ming
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 14 Issue: 2 Pages: 333-355
- DOI
  10.1016/j.jcmgh.2022.04.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07155, KAKENHI-PROJECT-18H05215
[Journal Article] HSF1 phosphorylation establishes an active chromatin state via the TRRAP TIP60 complex and promotes tumorigenesis2022
- Author(s)
  Fujimoto Mitsuaki、Takii Ryosuke、Matsumoto Masaki、Okada Mariko、Nakayama Keiich I.、Nakato Ryuichiro、Fujiki Katsunori、Shirahige Katsuhiko、Nakai Akira
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4355-4355
- DOI
  10.1038/s41467-022-32034-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19288, KAKENHI-PROJECT-20H05686, KAKENHI-PROJECT-21H02697, KAKENHI-PROJECT-20K21386, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-23K23870, KAKENHI-PROJECT-18H05215
[Journal Article] Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.2022
- Author(s)
  Mise S#, Matsumoto A#*, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI*.
- Journal Title
  
  Nat. Commun.
  
  Volume: 13(1) Issue: 1 Pages: 1071-1071
- DOI
  10.1038/s41467-022-28677-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-20K21397, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-17H06304, KAKENHI-PROJECT-20J11940, KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-21H02751, KAKENHI-PROJECT-20K15101, KAKENHI-PLANNED-20H05928
[Journal Article] LIGHTHOUSE illuminates therapeutics for a variety of diseases including COVID-192022
- Author(s)
  Shimizu Hideyuki、Kodama Manabu、Matsumoto Masaki、Orba Yasuko、Sasaki Michihito、Sato Akihiko、Sawa Hirofumi、Nakayama Keiichi I.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 11 Pages: 105314-105314
- DOI
  10.1016/j.isci.2022.105314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19288, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-21K17856, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-23K23870, KAKENHI-PROJECT-18H05215
[Journal Article] Phenotypic heterogeneity in individuals with MECOM variants in 2 families.2022
- Author(s)
  Niihori T, Tanoshima R, Sasahara Y, Sato A, Irie M, Saito-Nanjo Y, Funayama R, Shirota M, Abe T, Okuyama Y, Ishii N, Nakayama K, Kure S, Imaizumi M, Aoki Y.
- Journal Title
  
  Blood Adv.
  
  Volume: - Issue: 18 Pages: 5257-5261
- DOI
  10.1182/bloodadvances.2020003812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03637, KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-19K08855, KAKENHI-PROJECT-20K07546, KAKENHI-PROJECT-20K08766
[Journal Article] Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons2021
- Author(s)
  Ichihara Kazuya、Matsumoto Akinobu、Nishida Hiroshi、Kito Yuki、Shimizu Hideyuki、Shichino Yuichi、Iwasaki Shintaro、Imami Koshi、Ishihama Yasushi、Nakayama Keiichi I
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 13 Pages: 7298-7317
- DOI
  10.1093/nar/gkab549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04844, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-21H02404, KAKENHI-PROJECT-20J20906, KAKENHI-PROJECT-21J15131, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22406
[Journal Article] The autism-associated protein CHD8 is required for cerebellar development and motor function2021
- Author(s)
  Kawamura Atsuki、Katayama Yuta、Kakegawa Wataru、Ino Daisuke、Nishiyama Masaaki、Yuzaki Michisuke、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 1 Pages: 108932-108932
- DOI
  10.1016/j.celrep.2021.108932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05220, KAKENHI-PROJECT-20H03563, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-20H03420, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04716, KAKENHI-PUBLICLY-20H05057, KAKENHI-PUBLICLY-21H05619, KAKENHI-PROJECT-21H02847, KAKENHI-PROJECT-21J00911, KAKENHI-PROJECT-21K06421, KAKENHI-PROJECT-21K15726, KAKENHI-PROJECT-20H05628
[Journal Article] Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle2021
- Author(s)
  Egami Riku、Kokaji Toshiya、Hatano Atsushi、et al.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 3 Pages: 102217-102217
- DOI
  10.1016/j.isci.2021.102217
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19J10234, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PLANNED-18H05431, KAKENHI-PROJECT-20H03237
[Journal Article] A ubiquitin-like protein encoded by the “noncoding” RNA TINCR promotes keratinocyte proliferation and wound healing2021
- Author(s)
  Nita Akihiro、Matsumoto Akinobu、Tang Ronghao、Shiraishi Chisa、Ichihara Kazuya、Saito Daisuke、Suyama Mikita、Yasuda Tomoharu、Tsuji Gaku、Furue Masutaka、Katayama Bumpei、Ozawa Toshiyuki、Murata Teruasa、Dainichi Teruki、Kabashima Kenji、Hatano Atsushi、Matsumoto Masaki、Nakayama Keiichi I.
- Journal Title
  
  PLOS Genetics
  
  Volume: 17 Issue: 8 Pages: 1009686-1009686
- DOI
  10.1371/journal.pgen.1009686
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-21H02751, KAKENHI-PROJECT-21K08303, KAKENHI-PROJECT-20K21386, KAKENHI-PLANNED-20H05928
[Journal Article] A universal molecular prognostic score for gastrointestinal tumors2021
- Author(s)
  Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  npj Genomic Medicine
  
  Volume: 6 Issue: 1 Pages: 6-6
- DOI
  10.1038/s41525-021-00172-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19K20403
[Journal Article] Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism2021
- Author(s)
  Cherepanov Stanislav M.、Gerasimenko Maria、Yuhi Teruko、Furuhara Kazumi、Tsuji Chiharu、Yokoyama Shigeru、Nakayama Keiichi I.、Nishiyama Masaaki、Higashida Haruhiro
- Journal Title
  
  BMC Neuroscience
  
  Volume: 22 Issue: 1 Pages: 32-32
- DOI
  10.1186/s12868-021-00631-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-21H02847
[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021
- Author(s)
  Maimaiti Maihulan、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumi、Matsusaka Keisuke、Xu Minhui、Ando Keisuke、Saito Shinpei、Wakai Ken、Imamura Yusuke、Nakayama Keiichi、Kanai Yoshikatsu、Kaneda Atsushi、Ikehara Yuzuru、Ikeda Jun-Ichiro、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11478-11478
- DOI
  10.1038/s41598-021-90748-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K09572, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver2021
- Author(s)
  Matsuzaki Fumiko、Uda Shinsuke、Yamauchi Yukiyo、Matsumoto Masaki、Soga Tomoyoshi、Maehara Kazumitsu、Ohkawa Yasuyuki、Nakayama Keiichi I.、Kuroda Shinya、Kubota Hiroyuki
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 8 Pages: 109569-109569
- DOI
  10.1016/j.celrep.2021.109569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06577, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04847, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-18K15011, KAKENHI-PROJECT-20H03237, KAKENHI-PLANNED-17H06300
[Journal Article] Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders2021
- Author(s)
  Johmura Yoshikazu、Yamanaka Takehiro、Omori Satotaka、Wang Teh-Wei、Sugiura Yuki、Matsumoto Masaki、Suzuki Narumi、Kumamoto Soichiro、Yamaguchi Kiyoshi、Hatakeyama Seira、Takami Tomoyo、Yamaguchi Rui、Shimizu Eigo、Ikeda Kazutaka、Okahashi Nobuyuki、Mikawa Ryuta、Suematsu Makoto、Arita Makoto、Sugimoto Masataka et al
- Journal Title
  
  Science
  
  Volume: 371 Issue: 6526 Pages: 265-270
- DOI
  10.1126/science.abb5916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H04116
[Journal Article] The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells2021
- Author(s)
  Nita Akihiro、Muto Yoshiharu、Katayama Yuta、Matsumoto Akinobu、Nishiyama Masaaki、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 5 Pages: 108688-108688
- DOI
  10.1016/j.celrep.2021.108688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21397, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05220, KAKENHI-PROJECT-18H02707, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-20H03563, KAKENHI-PROJECT-20K21650, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-21H02847
[Journal Article] Identification and characterization of novel proteins associated with CHD42021
- Author(s)
  Sakaguchi Chihiro、Ichihara Kazuya、Nita Akihiro、Katayama Yuta、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 27 Issue: 1 Pages: 61-71
- DOI
  10.1111/gtc.12909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-20J20906
[Journal Article] Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation2020
- Author(s)
  Shirane Michiko、Wada Mariko、Morita Keiko、Hayashi Nahoki、Kunimatsu Reina、Matsumoto Yuki、Matsuzaki Fumiko、Nakatsumi Hirokazu、Ohta Keisuke、Tamura Yasushi、Nakayama Keiichi I.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4576-4576
- DOI
  10.1038/s41467-020-18413-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11733, KAKENHI-PROJECT-20K06730, KAKENHI-PROJECT-20K21413, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04907, KAKENHI-PROJECT-19H03174, KAKENHI-PROJECT-20H03255, KAKENHI-PROJECT-18K06962, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-15H05705
[Journal Article] Drug repositioning in cancer: The current situation in Japan.2020
- Author(s)
  Masuda T, Tsuruda Y, Matsumoto Y, Uchida H, Nakayama KI, Mimori K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111(4) Issue: 4 Pages: 1039-1046
- DOI
  10.1111/cas.14318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15323, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-20K08960, KAKENHI-PUBLICLY-20H05039, KAKENHI-PROJECT-19H03715
[Journal Article] A Fail-Safe System to Prevent Oncogenesis by Senescence Is Targeted by SV40 Small T Antigen2020
- Author(s)
  Kiyotaka Oshikawa, Masaki Matsumoto, Manabu Kodama, Hideyuki Shimizu, Keiichi I Nakayama
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 10 Pages: 2170-2186
- DOI
  10.1038/s41388-019-1139-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06543, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04903, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243
[Journal Article] Recent insight into the role of FBXW7 as a tumor suppressor2020
- Author(s)
  Yumimoto Kanae、Nakayama Keiichi I.
- Journal Title
  
  Seminars in Cancer Biology
  
  Volume: 未定 Pages: 1-15
- DOI
  10.1016/j.semcancer.2020.02.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-20K07592, KAKENHI-PROJECT-19J40055
[Journal Article] Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning2020
- Author(s)
  Shirane Michiko、Shoji Hirotaka、Hashimoto Yutaka、Katagiri Hiroyuki、Kobayashi Shizuka、Manabe Toshiya、Miyakawa Tsuyoshi、Nakayama Keiichi I.
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 146-146
- DOI
  10.1186/s13041-020-00693-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06901, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04876, KAKENHI-PUBLICLY-20H04907, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-20H03255
[Journal Article] A shift in glutamine nitrogen metabolism contributes to malignant progression of cancer.2020
- Author(s)
  Kodama M, Oshikawa K, Shimizu H, Yoshioka S, Takahashi M, Izumi Y, Bamba T, Tateishi C, Tomonaga T, Matsumoto M*, Nakayama KI*.
- Journal Title
  
  Nat. Commun.
  
  Volume: 11 Issue: 1 Pages: 1320-1320
- DOI
  10.1038/s41467-020-15136-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-17H06304, KAKENHI-PUBLICLY-18H04903, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-19K06543
[Journal Article] Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development.2020
- Author(s)
  Yamauchi, Y., Nita, A., Nishiyama, M., Muto, Y., Shimizu, H., Nakatsumi, H., Nakayama, K. I.
- Journal Title
  
  Genes Cells
  
  Volume: XX Issue: 6 Pages: 427-438
- DOI
  10.1111/gtc.12769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-18K19509, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-18K06962
[Journal Article] Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice2020
- Author(s)
  Kawamura Atsuki、Katayama Yuta、Nishiyama Masaaki、Shoji Hirotaka、Tokuoka Kota、Ueta Yoshifumi、Miyata Mariko、Isa Tadashi、Miyakawa Tsuyoshi、Hayashi-Takagi Akiko、Nakayama Keiichi I
- Journal Title
  
  Human Molecular Genetics
  
  Volume: - Issue: 8 Pages: 1274-1291
- DOI
  10.1093/hmg/ddaa036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22591, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-17J02750, KAKENHI-PROJECT-18K19509, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05220, KAKENHI-PLANNED-19H05723, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-20H03563
[Journal Article] Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components.2020
- Author(s)
  Nakagawa T, Nakayama K, Nakayama KI.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 1217 Pages: 147-171
- DOI
  10.1007/978-981-15-1025-0_10
- ISBN
  9789811510243, 9789811510250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-20K12157
[Journal Article] Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity2020
- Author(s)
  Kokaji Toshiya、Hatano Atsushi、Ito Yuki、et al.
- Journal Title
  
  Science Signaling
  
  Volume: 13 Issue: 660 Pages: 1236-1236
- DOI
  10.1126/scisignal.aaz1236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-20H04847, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-18H05431, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PROJECT-20H03237
[Journal Article] Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis2020
- Author(s)
  Matsuhisa Koji、Saito Atsushi、Cai Longjie、Kaneko Masayuki、Okamoto Takumi、Sakaue Fumika、Asada Rie、Urano Fumihiko、Yanagida Kanta、Okochi Masayasu、Kudo Yukitsuka、Matsumoto Masaki、Nakayama Keiichi I.、Imaizumi Kazunori
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 865-880
- DOI
  10.1096/fj.201901748r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06685, KAKENHI-PROJECT-19K16373, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06413, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H01424
[Journal Article] Artificial intelligence in oncology2020
- Author(s)
  Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Cancer Science
  
  Volume: 未定 Issue: 5 Pages: 1452-1460
- DOI
  10.1111/cas.14377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Cell cycle-dependent localization of the proteasome to chromatin2020
- Author(s)
  Kito Yuki、Matsumoto Masaki、Hatano Atsushi、Takami Tomoyo、Oshikawa Kiyotaka、Matsumoto Akinobu、Nakayama Keiichi I.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5801-5801
- DOI
  10.1038/s41598-020-62697-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04902, KAKENHI-PUBLICLY-19H04911, KAKENHI-PROJECT-18K19549, KAKENHI-PROJECT-19K06543, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21397, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-18H02707, KAKENHI-PLANNED-20H05930
[Journal Article] Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice2020
- Author(s)
  Wada Yoichi、Kikuchi Atsuo、Kaga Akimune、Shimizu Naoki、Ito Junya、Onuma Ryo、Fujishima Fumiyoshi、Totsune Eriko、Sato Ryo、Niihori Tetsuya、Shirota Matsuyuki、Funayama Ryo、Sato Kota、Nakazawa Toru、Nakayama Keiko、Aoki Yoko、Aiba Setsuya、Nakagawa Kiyotaka、Kure Shigeo
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 2 Pages: e1008628-e1008628
- DOI
  10.1371/journal.pgen.1008628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-17K10044, KAKENHI-PROJECT-18K19281
[Journal Article] Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain2020
- Author(s)
  Kawamura Atsuki、Abe Yoshifumi、Seki Fumiko、Katayama Yuta、Nishiyama Masaaki、Takata Norio、Tanaka Kenji F.、Okano Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 160-160
- DOI
  10.1186/s13041-020-00699-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-19K16031, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05027, KAKENHI-PUBLICLY-19H05220, KAKENHI-PUBLICLY-20H05057, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-20H03563
[Journal Article] Phase I dose‐escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer2020
- Author(s)
  Masuda Takaaki、Noda Miwa、Kogawa Takahiro、Kitagawa Dai、Hayashi Naoki、Jomori Takahito、Nakanishi Yoichi、Nakayama Keiichi I.、Ohno Shinji、Mimori Koshi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 924-931
- DOI
  10.1111/cas.14306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19K18057
[Journal Article] The role of Mediator and Little Elongation Complex in transcription termination2020
- Author(s)
  Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn P, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-20
- DOI
  10.1038/s41467-020-14849-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-19K22408, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K22401
[Journal Article] Loss of Fbxw7 impairs development of and induces heterogeneous tumor formation in the mouse mammary gland2020
- Author(s)
  Onoyama Ichiro、Nakayama Shogo、Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 24 Pages: 5515-5530
- DOI
  10.1158/0008-5472.can-20-0271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09646, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19J10033, KAKENHI-PROJECT-19K20403
[Journal Article] BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition2020
- Author(s)
  Sato Masaki、Matsumoto Mitsuyo、Saiki Yuriko、Alam Mahabub、Nishizawa Hironari、Rokugo Masahiro、Brydun Andrey、Yamada Shinji、Kaneko Mika K.、Funayama Ryo、Ito Mamoru、Kato Yukinari、Nakayama Keiko、Unno Michiaki、Igarashi Kazuhiko
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 6 Pages: 1279-1292
- DOI
  10.1158/0008-5472.can-18-4099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16H05410, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-19K07680
[Journal Article] Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development2020
- Author(s)
  Laukoter Susanne、Beattie Robert、Pauler Florian M.、Amberg Nicole、Nakayama Keiichi I.、Hippenmeyer Simon
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 195-195
- DOI
  10.1038/s41467-019-14077-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.2020
- Author(s)
  Wakabayashi Y, Tamura Y, Kouzaki K, Kikuchi N, Hiranuma K, Menuki K, Tajima T, Yamanaka Y, Sakai A, Nakayama KI, Kawamoto T, Kitagawa K, Nakazato K.
- Journal Title
  
  Am. J. Physiol. Regul. Integr. Comp. Physiol.
  
  Volume: 318 Issue: 4 Pages: 677-690
- DOI
  10.1152/ajpregu.00089.2019
- NAID
  120007089104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01085, KAKENHI-PROJECT-15K10499, KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-18H05215
[Journal Article] A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis2020
- Author(s)
  Tsukiyama Tadasuke、Zou Juqi、Kim Jihoon、Ogamino Shohei、Shino Yuki、Masuda Takamasa、Merenda Alessandra、Matsumoto Masaki、Fujioka Yoichiro、Hirose Tomonori、Terai Sayuri、Takahashi Hidehisa、Ishitani Tohru、Nakayama Keiichi I.、Ohba Yusuke、Koo Bon-Kyoung、Hatakeyama Shigetsugu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-020-18257-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-20K21386, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04823, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-19H05411, KAKENHI-PUBLICLY-20H04895, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-19H03412, KAKENHI-PROJECT-19K22401, KAKENHI-PLANNED-20H05930
[Journal Article] The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.2020
- Author(s)
  Nakagawa T, Hattori S, Nobuta R, Kimura R, Nakagawa M, Matsumoto M, Nagasawa Y, Funayama R, Miyakawa T, Inada T, Osumi N, Nakayama KI, Nakayama K.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 4 Pages: 101030-101030
- DOI
  10.1016/j.isci.2020.101030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-20K21386, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930
[Journal Article] Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells2019
- Author(s)
  Shimizu Hideyuki、Takeishi Shoichiro、Nakatsumi Hirokazu、Nakayama Keiichi I.
- Journal Title
  
  JCI Insight
  
  Volume: 4 Issue: 4
- DOI
  10.1172/jci.insight.125138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06962, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16H06276
[Journal Article] Biallelic variants/mutations of IL1RAP in patients with steroid-sensitive nephrotic syndrome2019
- Author(s)
  Niitsuma Sou、Kudo Hiroki、Kikuchi Atsuo、Hayashi Takaya、Kumakura Satoshi、Kobayashi Shuhei、Okuyama Yuko、Kumagai Naonori、Niihori Tetsuya、Aoki Yoko、So Takanori、Funayama Ryo、Nakayama Keiko、Shirota Matsuyuki、Kondo Shuji、Kagami Shoji、Tsukaguchi Hiroyasu、Iijima Kazumoto、Kure Shigeo、Ishii Naoto
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 4 Pages: 283-292
- DOI
  10.1093/intimm/dxz081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09719, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18H02572, KAKENHI-PROJECT-17K08875, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-19H03612, KAKENHI-PROJECT-18KK0244
[Journal Article] Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphangiomatosis2019
- Author(s)
  Ozeki Michio、Aoki Yoko、Nozawa Akifumi、Yasue Shiho、Endo Saori、Hori Yumiko、Matsuoka Kentaro、Niihori Tetsuya、Funayama Ryo、Shirota Matsuyuki、Nakayama Keiko、Fukao Toshiyuki
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 14 Issue: 1 Pages: 215-215
- DOI
  10.1186/s13023-019-1191-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-18K15704
[Journal Article] The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment2019
- Author(s)
  Takii Ryosuke、Fujimoto Mitsuaki、Matsumoto Masaki、Srivastava Pratibha、Katiyar Arpit、Nakayama Keiich I、Nakai Akira
- Journal Title
  
  The EMBO Journal
  
  Volume: 38 Issue: 24
- DOI
  10.15252/embj.2019102566
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06490, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-18H02625
[Journal Article] The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.2019
- Author(s)
  Morohoshi, A., Nakagawa, T., Nakano, S., Nagasawa, Y., Nakayama, K.
- Journal Title
  
  Dev Biol.
  
  Volume: 445 Issue: 2 Pages: 178-188
- DOI
  10.1016/j.ydbio.2018.10.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K19281, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-17K14955
[Journal Article] SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation.2019
- Author(s)
  Sugiyama S, Yumimoto K, Inoue I, Nakayama KI
- Journal Title
  
  GENE CELLS
  
  Volume: 印刷中 Issue: 5 Pages: 354-365
- DOI
  10.1111/gtc.12680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05795, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J40055
[Journal Article] Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity.2019
- Author(s)
  Yu Y, Nakagawa T, Morohoshi A, Nakagawa M, Ishida N, Suzuki N, Aoki M, Nakayama K.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 28 Issue: 20 Pages: 3486-3497
- DOI
  10.1093/hmg/ddz119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K07837, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281
[Journal Article] Recurrent de novo MAPK8IP3 variants cause neurological phenotypes2019
- Author(s)
  Iwasawa Shinya、Yanagi Kumiko、Kikuchi Atsuo、Kobayashi Yasuko、Haginoya Kazuhiro、Matsumoto Hiroshi、Kurosawa Kenji、Ochiai Masayuki、Sakai Yasunari、Fujita Atsushi、Miyake Noriko、Niihori Tetsuya、ら
- Journal Title
  
  Annals of Neurology
  
  Volume: － Issue: 6 Pages: 927-933
- DOI
  10.1002/ana.25481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10045, KAKENHI-PROJECT-18K07863, KAKENHI-PROJECT-18K19281, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-19K08281, KAKENHI-PROJECT-19K08289, KAKENHI-PROJECT-17H01539
[Journal Article] Germline-Activating RRAS2 Mutations Cause Noonan Syndrome2019
- Author(s)
  Niihori Tetsuya、Nagai Koki、Fujita Atsushi、Ohashi Hirofumi、Okamoto Nobuhiko、Okada Satoshi、Harada Atsuko、Kihara Hirotaka、Arbogast Thomas、Funayama Ryo、Shirota Matsuyuki、Nakayama Keiko、Abe Taiki、Inoue Shin-ichi、Tsai I-Chun、Matsumoto Naomichi、Davis Erica E.、Katsanis Nicholas、Aoki Yoko
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 104 Issue: 6 Pages: 1233-1240
- DOI
  10.1016/j.ajhg.2019.04.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0228, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-19H03620, KAKENHI-PROJECT-17K10045, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-18K15657, KAKENHI-PROJECT-17H04223
[Journal Article] A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients2019
- Author(s)
  Shimizu H, Nakayama KI
- Journal Title
  
  EBioMedicine
  
  Volume: 46 Pages: 150-159
- DOI
  10.1016/j.ebiom.2019.07.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215
[Journal Article] Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases2019
- Author(s)
  Honda Hiroyuki、Matsumoto Masaki、Shijo Masahiro、Hamasaki Hideomi、Sadashima Shoko、Suzuki Satoshi O、Aishima Shinichi、Kai Keita、Nakayama Keiichi I、Sasagasako Naokazu、Iwaki Toru
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 78 Issue: 10 Pages: 922-929
- DOI
  10.1093/jnen/nlz075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17011, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17K07097
[Journal Article] Potentials of C-C Motif Chemokine 2-C-C Chemokine Receptor Type 2 Blockers Including Propagermanium as Anticancer Agents2019
- Author(s)
  Yumimoto Kanae、Sugiyama Shigeaki、Mimori Koshi、Nakayama Keiichi I.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 7 Pages: 2090-2099
- DOI
  10.1111/cas.14075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-19J40055, KAKENHI-PROJECT-17K07171
[Journal Article] Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis2019
- Author(s)
  Muto Yoshiharu*、Moroishi Toshiro*、Ichihara Kazuya、Nishiyama Masaaki、Shimizu Hideyuki、Eguchi Hidetoshi、Moriya Kyoji、Koike Kazuhiko、Mimori Koshi、Mori Masaki、Katayama Yuta、Nakayama Keiichi I. (*Equal contribution)
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Issue: 4 Pages: 950-965
- DOI
  10.1084/jem.20180900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19433, KAKENHI-PROJECT-18K19509, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-19H03715
[Journal Article] Cancer‐associated fibroblasts secrete Wnt2 to promote cancer progression in colorectal cancer2019
- Author(s)
  Aizawa Takashi、Karasawa Hideaki、Funayama Ryo、Shirota Matsuyuki、Suzuki Takashi、Maeda Shimpei、Suzuki Hideyuki、Yamamura Akihiro、Naitoh Takeshi、Nakayama Keiko、Unno Michiaki
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Issue: 14 Pages: 6370-6382
- DOI
  10.1002/cam4.2523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-19K09188, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281
[Journal Article] Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data2018
- Author(s)
  Kawata Kentaro、Yugi Katsuyuki、Hatano Atsushi、Kokaji Toshiya、Tomizawa Yoko、Fujii Masashi、Uda Shinsuke、Kubota Hiroyuki、Matsumoto Masaki、Nakayama Keiichi I.、Kuroda Shinya
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 1 Pages: 82-93
- DOI
  10.1111/gtc.12655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04801, KAKENHI-PROJECT-16K12508, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-15H05582, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-18H05431
[Journal Article] Glutamate-rich WD40 repeat containing 1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.2018
- Author(s)
  Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, KI., Yoshida, K., Sugimoto, N. (Corresponding author), and Fujita, M.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Issue: 15 Pages: 213009-213009
- DOI
  10.1242/jcs.213009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07201, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-18J20791
[Journal Article] Combined mutation of Apc, Kras and Tgfbr2 effectively drives metastasis of intestinal cancer.2018
- Author(s)
  Sakai E, Nakayama M, Oshima H, Kouyama Y, Niida A, Fujii S, Ochiai A, Nakayama KI, Minori K, Suzuki Y, Hong CP, Ock CY, Kim SJ, Oshima M.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 5 Pages: 1334-1346
- DOI
  10.1158/0008-5472.can-17-3303
- NAID
  120006452378
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07111, KAKENHI-PROJECT-17K19608, KAKENHI-PUBLICLY-16H01576, KAKENHI-PUBLICLY-17H05616, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K07162
[Journal Article] Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb162018
- Author(s)
  Hosokawa Hiroyuki、Romero-Wolf Maile、Yui Mary A.、Ungerb?ck Jonas、Quiloan Maria L. G.、Matsumoto Masaki、Nakayama Keiichi I.、Tanaka Tomoaki、Rothenberg Ellen V.
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 12 Pages: 1427-1440
- DOI
  10.1038/s41590-018-0238-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-17K19606
[Journal Article] Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum2018
- Author(s)
  Abe Yuichi、Honsho Masanori、Itoh Ryota、Kawaguchi Ryoko、Fujitani Masashi、Fujiwara Kazushirou、Hirokane Masaaki、Matsuzaki Takashi、Nakayama Keiko、Ohgi Ryohei、Marutani Toshihiro、Nakayama Keiichi I、Yamashita Toshihide、Fujiki Yukio
- Journal Title
  
  Life Science Alliance
  
  Volume: 1 Issue: 6 Pages: 1-17
- DOI
  10.26508/lsa.201800062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07337, KAKENHI-PROJECT-18K19281, KAKENHI-INTERNATIONAL-15K21743, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04795, KAKENHI-PLANNED-26116007, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16K07275, KAKENHI-PROJECT-17K15621
[Journal Article] Rett-like features and cortical visual impairment in a Japanese patient with HECW2 mutation2018
- Author(s)
  Nakamura Haruhiko、Uematsu Mitsugu、Numata-Uematsu Yurika、Abe Yu、Endo Wakaba、Kikuchi Atsuo、Takezawa Yusuke、Funayama Ryo、Shirota Matsuyuki、Nakayama Keiko、Niihori Tetsuya、Aoki Yoko、Haginoya Kazuhiro、Kure Shigeo
- Journal Title
  
  Brain Dev
  
  Volume: 40 Issue: 5 Pages: 410-414
- DOI
  10.1016/j.braindev.2017.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04035
[Journal Article] Glucose deprivation induces primary cilium formation through mTORC1 inactivation2018
- Author(s)
  Takahashi, K.、Nagai, T.、Chiba, S.、Nakayama, K.、and Mizuno. K.
- Journal Title
  
  J Cell Sci
  
  Volume: 131 Issue: 1 Pages: 208769-208769
- DOI
  10.1242/jcs.208769
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04347, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-15H05596
[Journal Article] Hidden Peptides Encoded by Putative Noncoding RNAs2018
- Author(s)
  Matsumoto A, Nakayama KI.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 43 Issue: 1 Pages: 75-83
- DOI
  10.1247/csf.18005
- NAID
  130006742309
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19549, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04902, KAKENHI-PROJECT-18H02707, KAKENHI-PROJECT-16H06276
[Journal Article] Bone marrow PDGFRa+Sca-1+ enriched mesenchymal stem cells support survival of and antibody production by plasma cells in vitro through IL-6.2018
- Author(s)
  Atsuko Kayaba, Ari Itoh-Nakadai, Kunimichi Niibe, Matsuyuki Shirota, Ryo Funayama, Akiko Sugahara-Tobinai, Yi Li Wong, Masanori Inui, Keiko Nakayama, and Toshiyuki Takai.
- Journal Title
  
  Int Immu
  
  Volume: in press Issue: 6 Pages: 241-253
- DOI
  10.1093/intimm/dxy018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19539, KAKENHI-PROJECT-17K15714, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-15KK0328, KAKENHI-PROJECT-17K08874, KAKENHI-PROJECT-16K20480
[Journal Article] Bach2 Promotes B Cell Receptor?Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors2018
- Author(s)
  Miura Yuichi、Morooka Mizuho、Sax Nicolas、Roychoudhuri Rahul、Itoh-Nakadai Ari、Brydun Andrey、Funayama Ryo、Nakayama Keiko、Satomi Susumu、Matsumoto Mitsuyo、Igarashi Kazuhiko、Muto Akihiko
- Journal Title
  
  J Immunol
  
  Volume: - Issue: 8 Pages: 2882-2893
- DOI
  10.4049/jimmunol.1601863
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572
[Journal Article] Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3.2018
- Author(s)
  Nakayama S, Yumimoto K, Kawamura A, Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 293(15) Issue: 15 Pages: 5705-5714
- DOI
  10.1074/jbc.ra117.000741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-17J02750, KAKENHI-ORGANIZER-17H06391
[Journal Article] Nuclear-cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXK12018
- Author(s)
  Nakatsumi Hirokazu、Oka Takeru、Higa Tsunaki、Shirane Michiko、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 7 Pages: 599-605
- DOI
  10.1111/gtc.12597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06962, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16H06276
[Journal Article] TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation2018
- Author(s)
  Hashimoto Yutaka、Shirane Michiko、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 6 Pages: 418-434
- DOI
  10.1111/gtc.12583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018
- Author(s)
  Matsumoto Junichi、et al. Hatakeyama Shigetsugu、Matsumoto Masaki、Nakayama Keiichi I.、Otsuka Yutaro、Sabe Hisataka、Tsutsui Hiroyuki、Anzai Toshihisa
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 18 Pages: 2064-2066
- DOI
  10.1161/circulationaha.118.035212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks2018
- Author(s)
  Kawata Kentaro、Hatano Atsushi、Yugi Katsuyuki、Kubota Hiroyuki、Sano Takanori、Fujii Masashi、Tomizawa Yoko、Kokaji Toshiya、Tanaka Kaori Y.、Uda Shinsuke、Suzuki Yutaka、Matsumoto Masaki、Nakayama Keiichi I.、Saitoh Kaori、Kato Keiko、Ueno Ayano、Ohishi Maki、Hirayama Akiyoshi、Soga Tomoyoshi、Kuroda Shinya
- Journal Title
  
  iScience
  
  Volume: 7 Pages: 212-229
- DOI
  10.1016/j.isci.2018.07.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H06011, KAKENHI-PLANNED-17H06301, KAKENHI-PUBLICLY-18H04801, KAKENHI-ORGANIZER-18H05428, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16K12508, KAKENHI-PROJECT-17K19606, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-15H05582, KAKENHI-PLANNED-16H06577
[Journal Article] Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding2018
- Author(s)
  Hosokawa Hiroyuki、Ungerb?ck Jonas、Wang Xun、Matsumoto Masaki、Nakayama Keiichi I.、Cohen Sarah M.、Tanaka Tomoaki、Rothenberg Ellen V.
- Journal Title
  
  Immunity
  
  Volume: 48 Issue: 6 Pages: 1119-1134.e7
- DOI
  10.1016/j.immuni.2018.04.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-17K19606
[Journal Article] Transforming Growth Factor β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.2018
- Author(s)
  Nakagawa T, Hosogane M, Nakagawa M, Morohoshi A, Funayama R, Nakayama K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 38 Issue: 5
- DOI
  10.1128/mcb.00449-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-17K14955, KAKENHI-PROJECT-17H04035
[Journal Article] The promise of targeted proteomics for quantitative network biology2018
- Author(s)
  Matsumoto Masaki、Nakayama Keiichi I
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: 54 Pages: 88-97
- DOI
  10.1016/j.copbio.2018.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19606, KAKENHI-PUBLICLY-17H05534, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16H04730
[Journal Article] Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches.2018
- Author(s)
  Hui K, Katayama Y, Nakayama KI, Nomura J, Sakurai T.
- Journal Title
  
  Neurosci. Biobehav. Rev.
  
  Volume: 印刷中 Pages: 30121-0
- DOI
  10.1016/j.neubiorev.2018.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07119, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16K01948
[Journal Article] A large-scale targeted proteomics assay resource based on an in vitro human proteome.2017
- Author(s)
  Matsumoto M, Matsuzaki F, Oshikawa K, Goshima N, Mori M, Kawamura Y, Ogawa K, Fukuda E, Nakatsumi H, Natsume T, Fukui K, Horimoto K, Nagashima T, Funayama R, Nakayama K, Nakayama KI.
- Journal Title
  
  Nat Methods
  
  Volume: 14 Issue: 3 Pages: 251-258
- DOI
  10.1038/nmeth.4116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14612, KAKENHI-PROJECT-16K14664, KAKENHI-PUBLICLY-17H05625
[Journal Article] Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.2017
- Author(s)
  Hosogane, M., Bosu, L., Fukumoto, E., Yamada, H., Sato, S., Nakayama, K.
- Journal Title
  
  Genes Cells
  
  Volume: 印刷中 Issue: 4 Pages: 360-375
- DOI
  10.1111/gtc.12482
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26293433, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18453
[Journal Article] Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.2017
- Author(s)
  Baird L, Tsujita T, Kobayashi E, Funayama R, Nagashima T, Nakayama K, and Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 37 Issue: 4
- DOI
  10.1128/mcb.00439-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664
[Journal Article] SRRM4-dependent neuron-specific alternative splicing of protrudin transcripts regulates neurite outgrowth.2017
- Author(s)
  Ohnishi, T., Shirane, M., and Nakayama, K. I.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 709-719
- DOI
  10.1038/srep41130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04276, KAKENHI-PROJECT-14J03463, KAKENHI-PROJECT-25221303
[Journal Article] Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics.2017
- Author(s)
  Sato, Y., Katoh, Y., Matsumoto, M., Sato, M., Ebina, M., Itoh-Nakadai, A., Funayama, R., Nakayama, K., Unno, M., Igarashi, K.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 印刷中 Issue: 19 Pages: 8019-8037
- DOI
  10.1074/jbc.m116.774547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15H02506
[Journal Article] FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells.2017
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Kawamura, A., Nakayama, K. I.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 37 Issue: 8
- DOI
  10.1128/mcb.00470-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01516, KAKENHI-PROJECT-25221303, KAKENHI-PUBLICLY-16H01341, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-15K06835
[Journal Article] Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in <b><i>Fez1</i></b>-Deficient Mice2017
- Author(s)
  Sumitomo Akiko、Saka Ayumi、Ueta Keisho、Horike Kouta、Hirai Kazuko、Gamo Nao J.、Hikida Takatoshi、Nakayama Keiichi I.、Sawa Akira、Sakurai Takeshi、Tomoda Toshifumi
- Journal Title
  
  Molecular Neuropsychiatry
  
  Volume: 3 Issue: 4 Pages: 223-233
- DOI
  10.1159/000488081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01948, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K14579
[Journal Article] Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.2017
- Author(s)
  Muto, Y., *Nishiyama, M., Nita, A., Moroishi, T., *Nakayama, K. I.
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 16114-16114
- DOI
  10.1038/ncomms16114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01341, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15K06835, KAKENHI-PLANNED-17H06301
[Journal Article] Exome sequencing deciphers a germline MET mutation in familial epidermal growth factor receptor-mutant lung cancer.2017
- Author(s)
  Tode N, Kikuchi T, Sakakibara T, Hirano T, Inoue A, Ohkouchi S, Tamada T, Okazaki T, Koarai A, Sugiura H, Niihori T, Aoki Y, Nakayama K, Matsumoto K, Matsubara Y, Yamamoto M, Watanabe A, Nukiwa T, Ichinose M.
- Journal Title
  
  Cancer Sci
  
  Volume: 印刷中 Issue: 6 Pages: 1263-1270
- DOI
  10.1111/cas.13233
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26293195, KAKENHI-PROJECT-15K14473, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K15453, KAKENHI-PROJECT-17K16037, KAKENHI-PROJECT-17H04180, KAKENHI-PROJECT-15K09205, KAKENHI-PROJECT-15K15316
[Journal Article] A Bach2-Cebp gene regulatory network for the commitment of multipotent hematopoietic progenitors.2017
- Author(s)
  Itoh-Nakadai, A., Matsumoto, M., Kato, H., Sasaki, J., Uehara, Y., Sato, Y., Ebina-Shibuya, R., Morooka, M., Funayama, R., Nakayama, K., Ochiai, K., Muto, A. and Igarashi, K.
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 10 Pages: 2401-2414
- DOI
  10.1016/j.celrep.2017.02.029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18998, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-15KK0328
[Journal Article] Robotic crowd biology with Maholo LabDroids.2017
- Author(s)
  Yachie N; Robotic Biology Consortium (inc. Masaki Matsumoto)., Natsume T.
- Journal Title
  
  Nature Biotechnology
  
  Volume: 35 Issue: 4 Pages: 310-312
- DOI
  10.1038/nbt.3758
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16J06287, KAKENHI-PROJECT-15K18466, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15K06845
[Journal Article] The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.2017
- Author(s)
  Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.
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  Sci Signal. doi: 10.1126/scisignal.aah4117.
  
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- DOI
  10.1126/scisignal.aah4117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253092, KAKENHI-PROJECT-16H05509, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-15K18977, KAKENHI-PROJECT-15K15689, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-26462829
[Journal Article] Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp22017
- Author(s)
  Zhang Shihao、Chen Qinghua、Liu Qingxu、Li Yuxi、Sun Xiufeng、Hong Lixin、Ji Suyuan、Liu Chengyan、Geng Jing、Zhang Weiji、Lu Zhonglei、Yin Zhen-Yu、Zeng Yuanyuan、Lin Kwang-Huei、Wu Qiao、Li Qiyuan、Nakayama Keiko、Nakayama Keiich I.、Deng Xianming、Johnson Randy L.、Zhu Liang、Gao Daming、Chen Lanfen、Zhou Dawang
- Journal Title
  
  Cancer Cell
  
  Volume: 31 Issue: 5 Pages: 669-684.e7
- DOI
  10.1016/j.ccell.2017.04.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303, KAKENHI-PLANNED-17H06301
[Journal Article] Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.2017
- Author(s)
  Ishida N, Nakagawa T, Iemura SI, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 37 Issue: 4
- DOI
  10.1128/mcb.00347-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01737, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-17K10432
[Journal Article] Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.2017
- Author(s)
  Nakagawa T, Zhang T, Kushi R, Nakano S, Endo T, Nakagawa M, Yanagihara N, Zarkower D, Nakayama K.
- Journal Title
  
  Development
  
  Volume: 144 Pages: 4137-4147
- DOI
  10.1242/dev.158485
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-17K14955, KAKENHI-PROJECT-17H04035
[Journal Article] Inferring evolutionary responses of Anolis carolinensis introduced into the Ogasawara archipelago using whole genome sequence data2017
- Author(s)
  Tamate Satoshi、Iwasaki Watal M.、Krysko Kenneth L.、Camposano Brian J.、Mori Hideaki、Funayama Ryo、Nakayama Keiko、Makino Takashi、Kawata Masakado
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 18008-18008
- DOI
  10.1038/s41598-017-17852-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16H05767
[Journal Article] Dramatic response after functional hemispherectomy in a patient with epileptic encephalopathy carrying a de novo COL4A1 mutation.2017
- Author(s)
  Hino-Fukuyo, N., Kikuchi, A., Iwasaki, M., Sato, Y., Kubota, Y., Kobayashi, T., Nakayama, T., Haginoya, K., Arai-Ichinoi, N., Niihori, T., Sato, R., Suzuki, T., Kudo, H., Funayama, R., Nakayama, K., Aoki, Y., Kure, S.
- Journal Title
  
  Brain Dev.
  
  Volume: 39 Issue: 4 Pages: 337-340
- DOI
  10.1016/j.braindev.2016.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664
[Journal Article] NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.2017
- Author(s)
  Fukushima H, Shimizu K, Watahiki A, Hoshikawa S, Kosho T, Oba D, Sakano S, Arakaki M
- Journal Title
  
  Mol Cell
  
  Volume: Nov 16;68(4) Issue: 4 Pages: 645-658
- DOI
  10.1016/j.molcel.2017.10.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17310, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-17H04396, KAKENHI-PROJECT-16K15811, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-17H06531
[Journal Article] Structural basis for the assembly of the Ragulator-Rag GTPase complex.2017
- Author(s)
  Yonehara R, Nada S, Nakai T, Nakai M, Kitamura A, Ogawa A, Nakatsumi H, Nakayama KI, Li S, Standley DM, Yamashita E, Nakagawa A, Okada M.
- Journal Title
  
  Nat Commun.
  
  Volume: 8 Issue: 1 Pages: 1625-1625
- DOI
  10.1038/s41467-017-01762-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19596, KAKENHI-PUBLICLY-17H06004, KAKENHI-PLANNED-26114006, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H04296
[Journal Article] The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.2017
- Author(s)
  Hidaka, T., Ogawa, E., Kobayashi, E.H., Suzuki, T., Funayama, R., Nagashima, T., Fujimura, T., Aiba, S., Nakayama, K., Okuyama, R., Yamamoto, M.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 18 Issue: 1 Pages: 64-73
- DOI
  10.1038/ni.3614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K10143, KAKENHI-PROJECT-17K15590, KAKENHI-PROJECT-17H04240
[Journal Article] Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages2017
- Author(s)
  Nakatsumi Hirokazu、Matsumoto Masaki、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 9 Pages: 2471-2486
- DOI
  10.1016/j.celrep.2017.11.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19606, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-16H04730, KAKENHI-PLANNED-17H06301
[Journal Article] mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.2017
- Author(s)
  Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, Saghatelian A, Nakayama KI, Clohessy JG, Pandolfi PP.
- Journal Title
  
  Nature
  
  Volume: 541 Issue: 7636 Pages: 228-232
- DOI
  10.1038/nature21034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-25221303
[Journal Article] Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.2017
- Author(s)
  Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N, Okamura Y, Kinoshita K, Kometani K, Kurosaki T, Muto A, Ichinose M, Yamashita M, Igarashi K.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 292 Issue: 44 Pages: 18098-18112
- DOI
  10.1074/jbc.m117.808535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04742, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16H06640, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15508, KAKENHI-PROJECT-16K19158
[Journal Article] Lack of genetic variation prevents adaptation at the geographic range margin in a damselfly.2016
- Author(s)
  Takahashi, Y., Suyama, Y., Matsuki, Y., Funayama, R., Nakayama, K., Kawata, M.
- Journal Title
  
  Mol. Ecol.
  
  Volume: 25 Issue: 18 Pages: 4450-4460
- DOI
  10.1111/mec.13782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664
[Journal Article] p57(Kip2) knock-in mouse reveals CDK-independent contribution in the development of Beckwith-Wiedemann syndrome2016
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  Duquesnes, N., Callot, C., Jeannot, P., Daburon, V., Nakayama, K. I., Manenti, S., Davy, A., Besson, A.
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  J. Pathol.
  
  Volume: 239 Issue: 3 Pages: 250-261
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  10.1002/path.4721
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Journal Article] Wnt-beta-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer.2016
- Author(s)
  Kobayashi, M., Funayama, R., Ohnuma, S., Unno, M., Nakayama, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 12 Pages: 1776-1784
- DOI
  10.1111/cas.13097
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K07107
[Journal Article] Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis.2016
- Author(s)
  Matsumoto M, Kondo K, Shiraki T, Brydun A, Funayama R, Nakayama K, Yaegashi N, Katagiri H, Igarashi K.
- Journal Title
  
  Genes Cells.
  
  Volume: in press Issue: 6 Pages: 553-567
- DOI
  10.1111/gtc.12365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059
[Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.2016
- Author(s)
  Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 11624-11624
- DOI
  10.1038/ncomms11624
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228
[Journal Article] Lack of Transcription Triggers H3K27me3 Accumulation in the Gene Body.2016
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  Hosogane, M., Funayama, R., Shirota, M., Nakayama, K.
- Journal Title
  
  Cell Rep.
  
  Volume: 16 Issue: 3 Pages: 696-706
- DOI
  10.1016/j.celrep.2016.06.034
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K18453
[Journal Article] CHD8 haploinsufficiency results in autistic-like phenotypes in mice2016
- Author(s)
  Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T., Nakayama, K. I.
- Journal Title
  
  Nature
  
  Volume: 537 Issue: 7622 Pages: 675-679
- DOI
  10.1038/nature19357
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01291, KAKENHI-PUBLICLY-15H01516, KAKENHI-PUBLICLY-16H01341, KAKENHI-PLANNED-16H06462, KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K06835, KAKENHI-PROJECT-16K13110, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25221303
[Journal Article] The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis.2016
- Author(s)
  Ebina-Shibuya, R., Watanabe-Matsui, M., Matsumoto, M., Itoh-Nakadai, A., Funayama, R., Nakayama, K., Muto, A., Igarashi, K.
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  J. Biochem.
  
  Volume: 160 Pages: 333-344
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  40021050454
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- Data Source
  KAKENHI-PROJECT-26293059
[Journal Article] The expression of miR-125b-5p is increased in the serum of patients with chronic hepatitis B infection and inhibits the detection of hepatitis B virus surface antigen.2016
- Author(s)
  Ninomiya M, Kondo Y, Kimura O, Funayama R, Nagashima T, Kogure T, Morosawa T, Tanaka Y, Nakayama K, Shimosegawa T.
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  J Viral Hepat.
  
  Volume: in press Issue: 5 Pages: 330-9
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  10.1111/jvh.12522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-16K09335
[Journal Article] Human genetic variation database, a reference database of genetic variations in the Japanese population.2016
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  Higasa K, Miyake N, Yoshimura J, Okamura K, Niihori T, Saitsu H, Doi K, Shimizu M, Nakabayashi K, Aoki Y, Tsurusaki Y, Morishita S, Kawaguchi T, Migita O, (中略), Matsumoto N, Matsuda F.
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  J Hum Genet.
  
  Volume: advance online publication Issue: 6 Pages: 547-553
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  10.1038/jhg.2016.12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860258, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-15K19660, KAKENHI-PROJECT-16K07137, KAKENHI-PROJECT-15KK0293
[Journal Article] The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.2015
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  Wong WF, Kohu K, Nagashima T, Funayama R, Matsumoto M, Movahed E, Tan GM, Yeow TC, Looi CY, Kurokawa M, Osato M, Igarashi K, Nakayama K, Satake M.
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  Mol Immunol.
  
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  10.1016/j.molimm.2015.08.012
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- Data Source
  KAKENHI-PROJECT-15H04312, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-26293059
[Journal Article] F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner2015
- Author(s)
  Yumimoto, K., Akiyoshi, S., Ueo, H., Sagara, Y., Onoyama, I., Ueo, H., Ohno, S., Mori, M., Mimori, K., Nakayama, K. I.
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  J. Clin. Invest.
  
  Volume: 125 Issue: 2 Pages: 621-635
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  10.1172/jci78782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25860241, KAKENHI-PROJECT-26670608, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H05791
[Journal Article] Genomic analysis identifies candidate pathogenic variants in 9 of 18 patients with unexplained West syndrome.2015
- Author(s)
  Hino-Fukuyo N, Kikuchi A, Arai-Ichinoi N, Niihori T, Sato R, Suzuki T, Kudo H, Sato Y, Nakayama T, Kakisaka Y, Kubota Y, Kobayashi T, Funayama R, Nakayama K, Uematsu M, Aoki Y, Haginoya K, Kure S.
- Journal Title
  
  Hum Genet.
  
  Volume: 134 Issue: 6 Pages: 649-658
- DOI
  10.1007/s00439-015-1553-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-24591498, KAKENHI-PROJECT-25461536, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-26293059
[Journal Article] Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells2015
- Author(s)
  Shohei Furutachi, Hiroaki Miya, Tomoyuki Watanabe, Hiroki Kawai, Norihiko Yamasaki, Yujin Harada, Itaru Imayoshi, Mark Nelson, Keiichi I. Nakayama, Yusuke Hirabayashi and Yukiko Gotoh
- Journal Title
  
  Nature Neuroscience
  
  Volume: 印刷中 Issue: 5 Pages: 657-65
- DOI
  10.1038/nn.3989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25891008, KAKENHI-PLANNED-22123003, KAKENHI-PUBLICLY-15H01291, KAKENHI-PROJECT-15H02357, KAKENHI-PROJECT-15K15086, KAKENHI-PROJECT-25221303
[Journal Article] Role of the Atg9a gene in intrauterine growth and survival of fetal mice.2015
- Author(s)
  Kojima T, Yamada T, Akaishi R, Furuta I, Saitoh T, Nakabayashi K, Nakayama KI, Nakayama K, Akira S, Minakami H
- Journal Title
  
  Reprod.Biol.
  
  Volume: 15 Issue: 3 Pages: 131-138
- DOI
  10.1016/j.repbio.2015.05.001
- NAID
  120005828503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14951, KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-26111514, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26713005
[Journal Article] CRL4 E3 Ligase Promotes Monoubiquitylation and Chromatin Binding of TET Dioxygenases2015
- Author(s)
  Nakagawa, T., Lv, L., Nakagawa, M., Yu, Y., Yu, C., D'Alessio, A. C., Nakayama, K., Fan, H., Chen, X. & Xiong, Y.
- Journal Title
  
  Mol Cell
  
  Volume: 57 Issue: 2 Pages: 247-260
- DOI
  10.1016/j.molcel.2014.12.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25891003, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26670085
[Journal Article] Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia.2015
- Author(s)
  Niihori T, Ouchi-Uchiyama M, Sasahara Y, Kaneko T, Hashii Y, Irie M, Sato A, Saito-Nanjo Y, Funayama R, Nagashima T, Inoue S, Nakayama K, Ozono K, Kure S, Matsubara Y, Imaizumi M, Aoki Y.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 97 Issue: 6 Pages: 848-854
- DOI
  10.1016/j.ajhg.2015.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26830064
[Journal Article] S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation2015
- Author(s)
  Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K
- Journal Title
  
  Molecular and cellular biology
  
  Volume: 20 Issue: 20 Pages: 3517-3527
- DOI
  10.1128/mcb.00343-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18365, KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] Protein monoubiquitylation: targets and diverse functions2015
- Author(s)
  Nakagawa T, Nakayama K
- Journal Title
  
  Genes to cells
  
  Volume: 7 Issue: 7 Pages: 543-562
- DOI
  10.1111/gtc.12250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] FBXL12-mediated degradation of ALDH3 is essential for trophoblast differentiation during placental development.2015
- Author(s)
  Nishiyama, M., Nita, A., Yumimoto, K., Nakayama, K. I.
- Journal Title
  
  Stem Cells
  
  Volume: 33 Issue: 11 Pages: 3327-3340
- DOI
  10.1002/stem.2088
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06835, KAKENHI-PUBLICLY-25112517, KAKENHI-PUBLICLY-15H01186, KAKENHI-PUBLICLY-15H01291, KAKENHI-PUBLICLY-15H01516, KAKENHI-PROJECT-15K15086, KAKENHI-PROJECT-25221303
[Journal Article] Liver maturation deficiency in p57Kip2-/- mice occurs in a hepatocytic p57Kip2 expression-independent manner.2015
- Author(s)
  agida A, Chikada H, Ito K, Umino A, Kato-Itoh M, Yamazaki Y, Sato H, Kobayashi T, Yamaguchi T, Nakayama KI, Nakauchi H, Kamiya A.
- Journal Title
  
  Dev Biol.
  
  Volume: 407(2) Issue: 2 Pages: 331-43
- DOI
  10.1016/j.ydbio.2015.07.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-26293178, KAKENHI-PROJECT-25221303
[Journal Article] Mutations in PIGL in a patient with Mabry syndrome.2015
- Author(s)
  Fujiwara I, Murakami Y, Niihori T, Kanno J, Hakoda A, Sakamoto O, Okamoto N, Funayama R, Nagashima T, Nakayama K, Kinoshita T, Kure S, Matsubara Y, Aoki Y.
- Journal Title
  
  Am J Med Genet A.
  
  Volume: in press Issue: 4 Pages: 777-785
- DOI
  10.1002/ajmg.a.36987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25461535, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells2014
- Author(s)
  Shoichiro Takeishi, Keiichi I. Nakayama
- Journal Title
  
  British Journal of Cancer
  
  Volume: 111 Issue: 6 Pages: 1054-1059
- DOI
  10.1038/bjc.2014.259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Journal Article] TBX1 Mutation Identified by Exome Sequencing in a Japanese Family with 22q11.2 Deletion Syndrome-like Craniofacial Features and Hypocalcemia.2014
- Author(s)
  Ogata T*, Niihori T, Tanaka N, Kawai M, Nagashima T, Funayama R, Nakayama K, Nakashim S, Kato F, Fukami M, Aoki Y, Matsubara Y
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 3 Pages: e91598-e91598
- DOI
  10.1371/journal.pone.0091598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23791148, KAKENHI-PLANNED-24119005, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-26830064
[Journal Article] HCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases2014
- Author(s)
  Kondo Y, Ninomiya M, Kimura O, Machida K, Funayama R, Nagashima T, Kobayashi K, Kakazu E, Kato T, Nakayama K, Lai MM, Shimosegawa T.
- Journal Title
  
  PLoS One
  
  Volume: 9(6) Issue: 6 Pages: e98521-e98521
- DOI
  10.1371/journal.pone.0098521
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460970, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26830064
[Journal Article] Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.2014
- Author(s)
  Lu Z
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3463-3463
- DOI
  10.1038/ncomms4463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25221303
[Journal Article] Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal2014
- Author(s)
  Kanatsu-Shinohara, M., Onoyama, I., Nakayama, K. I., Shinohara, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 111 Issue: 24 Pages: 8826-8831
- DOI
  10.1073/pnas.1401837111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25221303
[Journal Article] Identification of acquired mutations by whole-genome sequencing in GATA-2 deficiency evolving into myelodysplasia and acute leukemia.2014
- Author(s)
  Fujiwara, T., Fukuhara, N., Funayama, R., Nariai, N., Kamata, M., Nagashima, T., Kojima, K., Onishi, Y., Sasahara, Y., Ishizawa, K., Nagasaki, M., Nakayama, K. & Harigae, H
- Journal Title
  
  Ann Hematol
  
  Volume: 93 Issue: 9 Pages: 1515-1522
- DOI
  10.1007/s00277-014-2090-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26860716
[Journal Article] p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling.2014
- Author(s)
  Matsumoto, A., Takeishi, S., Nakayama, K. I.
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 22 Pages: 3429-39
- DOI
  10.1182/blood-2013-10-532390
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Journal Article] GNE myopathy associated with congenital thrombocytopenia: a report of two siblings.2014
- Author(s)
  Izumi R, Niihori T, Suzuki N, Sasahara Y, Nishiyama A, Nishiyama S, Endo K, Kato M, Warita H, Konno H, Tateyama M, Nagashima T, Funayama R, Nakayama K, Kure S, Matsubara Y, Aoki Y, Aoki M.
- Journal Title
  
  Neuromuscul. Disord.
  
  Volume: 24(12) Issue: 12 Pages: 1068-1072
- DOI
  10.1016/j.nmd.2014.07.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591528, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26830064
[Journal Article] F-box and WD repeat domain containing-7 (Fbxw7) targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation2013
- Author(s)
  Yumimoto K., Matsumoto M., Onoyama I., Imaizumi K., Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 40 Pages: 28488-502
- DOI
  10.1074/jbc.m113.465179
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PUBLICLY-24116518, KAKENHI-PUBLICLY-25134714, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-25650069, KAKENHI-PROJECT-25860241
[Journal Article] p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis2013
- Author(s)
  Furutachi S, Matsumoto A, Nakayama K.I, Gotoh Y
- Journal Title
  
  EMBO J.
  
  Volume: 32 Issue: 7 Pages: 970-981
- DOI
  10.1038/emboj.2013.50
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22123003, KAKENHI-PROJECT-25221303
[Journal Article] Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.2013
- Author(s)
  Zhao H
- Journal Title
  
  Cancer Cell
  
  Volume: 24 Issue: 5 Pages: 645-659
- DOI
  10.1016/j.ccr.2013.09.021
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25221303
[Journal Article] Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex2013
- Author(s)
  Yumimoto, K. Muneoka, T. Tsuboi, T. Nakayama, K. I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 45 Pages: 32766-32776
- DOI
  10.1074/jbc.m113.511303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-25860241
[Journal Article] Impaired ovarian development and reduced fertility in female mice deficient in Skp2.2011
- Author(s)
  Fotovati, A., S.Abu-Ali, K.Nakayama, K.I.Nakayama
- Journal Title
  
  J Anat 218
  
  Pages: 668-677
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Impaired ovarian development and reduced fertility in female mice deficient in Skp2.2011
- Author(s)
  Fotovati A, Abu-Ali S, Nakayama K, Nakayama KI
- Journal Title
  
  J Anat.
  
  Volume: 未定(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumoto A, Tateishi Y, Onoyama I, Okita Y, Nakayama K, Nakayama KI
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 749-755
- NAID
  10029292153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Impaired ovarian development and reduced fertility in female mice defic ient in Skp2.2011
- Author(s)
  Fotovati A, Abu-Ali S, Nakayama K, Nakayama KI
- Journal Title
  
  J Anat.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Fbxw7beta resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumoto, A., Y.Tateishi, I.Onoyama, Y.Okita, K.Nakayama, K.I.Nakayama
- Journal Title
  
  Cancer Sci 102
  
  Pages: 749-755
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumoto A, Tateishi Y, Onoyama I, Okita Y, Nakayama K, Nakayama KI
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 749-755
- NAID
  10029292153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657052
[Journal Article] Fbxw7 βresides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumoto A, Tateishi Y, Onoyama I, Okita Y, Nakayama K, Nakayama KI
- Journal Title
  
  Cancer SciCancer Sci. 102
  
  Pages: 749-755
- NAID
  10029292153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumoto A, Tateishi Y, Onoyama I, Okita, Y, Nakayama K, Nakayama KI
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 749-755
- NAID
  10029292153
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki T, Kon S, Ronn RE, Henmi Y, Watanabe T, Nakayama K, Tanabe K, Satake M
- Journal Title
  
  Cell Struct Funct.
  
  Volume: 36 Pages: 83-95
- NAID
  130004137566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657052
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki T, Kon S, Ronn RE, Henmi Y, Watanabe T, Nakayama K, Tanabe K, Satake M
- Journal Title
  
  Cell Struct.Funct. 36
  
  Pages: 83-95
- NAID
  130004137566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki T, Kon S, Ronn RE, Henmi Y, Watanabe T, Nakayama K, Tanabe K, Satake M
- Journal Title
  
  Cell Struct Funct.
  
  Volume: 36 Pages: 83-95
- NAID
  130004137566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Impaired ovarian development and reduced fertility in female mice deficient in Skp2.2011
- Author(s)
  Fotovati A, Abu-Ali S, Nakayama K, Nakayama KI
- Journal Title
  
  J Anat.
  
  Volume: (未定印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki, T., S.Kon, R.E.Ronn, Y.Henmi, Y.Kobayashi, T.Watanabe, K.Nakayama, K.Tanabe, M.Satake
- Journal Title
  
  Cell Struct Funct 36
  
  Pages: 83-95
- NAID
  130004137566
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Impaired ovarian development and reduced fertility in female mice deficient in Skp2.2011
- Author(s)
  Fotovati A, Abu-Ali S, Nakayama K, Nakayama KI
- Journal Title
  
  J Anat.
  
  Volume: 印刷中(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657052
[Journal Article] Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.2011
- Author(s)
  Matsumot A, Tateishi Y, Onoyama I, Okita Y, Nakayama K, Nakayama KI
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 749-755
- NAID
  10029292153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki T, Kon S, Ronn RE, Ilenmi Y, Watanabe T, Nakayama K, Tanabe K, Satake M
- Journal Title
  
  Cell Struct Funct.
  
  Volume: 36 Pages: 83-95
- NAID
  130004137566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Localization of SMAP2 to the TGN and its Function in the Regulation of TGN Protein Transport.2011
- Author(s)
  Funaki T, Kon S, Ronn RE, Henmi Y, Watanabe T, Nakayama K, Tanabe K, Satake M
- Journal Title
  
  Cell Struct Funct.
  
  Volume: 36 Pages: 83-95
- NAID
  130004137566
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Impaired ovarian development and reduced fertility in female mice deficient in Skp2.2011
- Author(s)
  Fotovati A, Abu-Ali S, Nakayama K,Nakayama KI
- Journal Title
  
  J Anat. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2011
- Author(s)
  Onoyama, I., A.Suzuki, A.Matsumoto, K.Tomita, H.Katagiri, Y.Oike, K.Nakayama, K.I.Nakayama
- Journal Title
  
  J Clin Invest 121
  
  Pages: 342-354
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya Y, Asano T, Nakayama K, Kato T Jr, Karin M, Kamata H
- Journal Title
  
  Mol Cell.
  
  Volume: 39 Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657052
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/-mice.2010
- Author(s)
  Wang, H., F.Bauzon, P.Ji, X.Xu, D.Sun, J.Locker, R.S.Sellers, K.Nakayama, K.I.Nakayama, D.CobrinikL. Zhu
- Journal Title
  
  Nat Genet 42
  
  Pages: 83-88
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya Y, Asano T, Nakayama K, Kato T Jr, Karin M, Kamata H
- Journal Title
  
  Mol Cell.
  
  Volume: 39 Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1(+/-) mice.2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L.
- Journal Title
  
  Nat Genet 42
  
  Pages: 83-83
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L
- Journal Title
  
  Nat Genet 42
  
  Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts.2010
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K.
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1798
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Skp2 is required for survivalof aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1(+/-) mice.2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L.
- Journal Title
  
  Nat.Genet. 42
  
  Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L
- Journal Title
  
  Nat Genet 42
  
  Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2010
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Oike Y, Nakayama K, Nakayama KI
- Journal Title
  
  J CIin Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657052
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L
- Journal Title
  
  Nat Genet 42
  
  Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Fbxw7 controls lipid metabolism and cell fate decision in the liver in mice.2010
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Oike Y, Nakayama K, Nakayama KI.
- Journal Title
  
  J.Clin.Invest. 121
  
  Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalphaubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya Y, Asano T, Nakayama K, Kato T, Jr Karin M,Kamata H.
- Journal Title
  
  Mol.Cell 39
  
  Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2010
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Dike Y, Nakayama K, Nakayama KI
- Journal Title
  
  J Clin Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya, Y., T.Asano, K.Nakayama, T.Kato, Jr., M.Karin, H.Kamata
- Journal Title
  
  Mol Cell 39
  
  Pages: 570-582
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya Y, Asano T, Nakayama K, Kato T Jr, Karin M, Kamata H
- Journal Title
  
  Mol Cell.
  
  Volume: 39 Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts.2010
- Author(s)
  Masuda, K., Y.Ishikawa, I.Onoyama, M.Unno, I.M. de Alboran, K.I., Nakayama, K.Nakavama
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1809
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts.2010
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K.
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2010
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Oike Y, Nakayama K, Nakayama KI
- Journal Title
  
  J Clin Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver2010
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tbmita K, Katagiri H, Oike Y, Nakayama K, Nakayama Ki
- Journal Title
  
  J Clin Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.2010
- Author(s)
  Tsuchiya Y. Asano T, Nakayama K, Kato T Jr, Karin M, Kamata H
- Journal Title
  
  Mol Cell.
  
  Volume: 39 Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Mechanoregulation of proliferation.2009
- Author(s)
  Jiang X, Austin PF, Niederhoff RA, Manson SR, Riehm JJ, Cook BL, Pengue G, Chitaley K, Nakayama K, Nakayama KI, Weintraub SJ
- Journal Title
  
  Mol Cell Biol 18
  
  Pages: 5104-5114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] S-phase kinase-associated protein-2(Skp2)promotes vascular smooth muscle cell proliferation and neointima formation in vivo.2009
- Author(s)
  Wu YJ, Sala-Newby GB, Shu KT, Yeh HI, Nakayama KI, Nakayama K, Newby AC, Bond M
- Journal Title
  
  J Vasc Surg. 50
  
  Pages: 1135-1142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Protein kinase C[delta] differentially regulates platelet functional responses.2009
- Author(s)
  Chari, R., T.Getz, B.Nagy, Jr., K.Bhavaraju, Y.Mao, Y.S.Bynagari, S.Murugappan, K.Nakayama, S.P.Kunapuli
- Journal Title
  
  Arterioscler Thromb Vasc Biol 29
  
  Pages: 699-705
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2009
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Mechanoregulation of proliferation.2009
- Author(s)
  Jiang, X., P.F.Austin, R.A.Niederhoff, S.R.Manson, J.J.Riehm, B.L.Cook, G.Pengue, K.Chitaley, K.Nakayama, K.I.Nakayama, S.J.Weintraub
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 5104-5114
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2009
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Protein kinase C[delta] differentially regulates platelet functional responses.2009
- Author(s)
  Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 29
  
  Pages: 699-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration2009
- Author(s)
  Kimura T, Sakai M, Tabu K, Wang L, Tsunematsu R, Tsuda M, Sawa H, Nagashima K, Nishihara H, Hatakeyama S, Nakayama K, Ladanyi M, Tanaka S, Nakayama KI
- Journal Title
  
  Lab Invest 89
  
  Pages: 645-656
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] The mechanoregulation of proliferation.2009
- Author(s)
  Jiang X, Austin PF, Niederhoff RA, Manson SR, Riehm JJ, Cook BL, Pengue G, Chitaley K, Nakayama K, Nakayama KI, Weintraub SJ.
- Journal Title
  
  Mol.Cell.Biol. 18
  
  Pages: 5104-5114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Mechanoregulation of proliferation2009
- Author(s)
  Jiang X, Austin PF, Niederhoff RA, Manson SR, Riehm JJ, Cook BL, Pengue G, Chitaley K, Nakayama K, Nakayama KI, Weintraub SJ
- Journal Title
  
  Mol Cell Biol 18
  
  Pages: 5104-5114
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration.2009
- Author(s)
  Kimura T, Sakai M, Tabu K, Wang L, Tsunematsu R, Tsuda M, Sawa H, Nagashima K, Nishihara H, Hatakeyama S, Nakayama K, Ladanyi M, Tanaka S, Nakayama KI
- Journal Title
  
  Lab Invest 89
  
  Pages: 645-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Mechanoregulation of proliferation.2009
- Author(s)
  Jiang X, Austin PF, Niederhoff RA, Manson SR, Riehm JJ, Cook BL, Pengue G, Chitaley K, Nakayama K, Nakayama KI, Weintraub SJ
- Journal Title
  
  Mol Cell Biol 18
  
  Pages: 5104-5114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo.2009
- Author(s)
  Wu YJ, Sala-Newby, GB, Shu KT, Yeh HI, Nakayama KI, Nakayama K, Newby AC, Bond MJ.
- Journal Title
  
  J.Vasc.Surg. 50
  
  Pages: 1135-1142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Protein kinase C[delta] differentially regulates platelet functional responses.2009
- Author(s)
  Chari R, Getz T, Nagy B, Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP.
- Journal Title
  
  Arterioscler. Thromb.Vasc.Biol. 29
  
  Pages: 699-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Protein kinase C[delta]differentially regulates platelet functional responses2009
- Author(s)
  Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP
- Journal Title
  
  Arterioscler Thromb Vase Biol. 29
  
  Pages: 699-705
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo.2009
- Author(s)
  Wu, Y.J., G.B.Sala-Newby, K.T.Shu, H.I.Yeh, K.I.Nakayama, K.Nakayama, A.C.Newby, M.Bond
- Journal Title
  
  J Vase Surg 50
  
  Pages: 1135-1142
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration.2009
- Author(s)
  Kimura T, Sakai M, Tabu K, Wang L, Tsunematsu R, Tsuda M, Sawa H, Nagashima K, Nishihara H, Hatakeyama S, Nakayama K, Ladanyi M, Tanaka S, Nakayama KI
- Journal Title
  
  Lab Invest 89
  
  Pages: 645-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model.2009
- Author(s)
  Susaki E, Nakayama K, Yamasaki L, Nakayama KI.
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 5192-5192
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2009
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
- Journal Title
  
  Oncogene 29
  
  Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] S-phase kinase-associated protein-2(Skp2)promotes vascular smooth muscle cell proliferation and neointima formation in vivo2009
- Author(s)
  Wu YJ, Sala-Newby GB, Shu KT, Yeh HI, Nakayama KI, Nakayama K, Newby AC, Bond M
- Journal Title
  
  J Vasc Surg. 50
  
  Pages: 1135-1142
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] S-phase kinase-associated protein-2(Skp2)promotes vascular smooth muscle cell proliferation and neointima formation in vivo.2009
- Author(s)
  Wu YJ, Sala-Newby GB, Shu KT, Yeh HI, Nakayama KI, Nakayama K, Newby AC, Bond M
- Journal Title
  
  J Vasc Surg. 50
  
  Pages: 1135-1142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Protein kinase C[delta]differentially regulates platelet functional responses.2009
- Author(s)
  Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 29
  
  Pages: 699-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration.2009
- Author(s)
  Kimura T, Sakai M, Tabu K, Wang L, Tsunematsu R, Tsuda M, Sawa H, Nagashima K, Nishihara H, Hatakeyama S, Nakayama K, Ladanyi M, Tanaka S, Nakayama KI.
- Journal Title
  
  Lab.Invest. 89
  
  Pages: 645-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration.2009
- Author(s)
  Kimura, T., M.Sakai, K.Tabu, L.Wang, R.Tsunematsu, M.Tsuda, H.Sawa, K.Nagashima, H.Nishihara, S.Hatakeyama, K.Nakayama, M.Ladanyi, S.Tanaka, K.I.Nakayama
- Journal Title
  
  Lab Invest 89
  
  Pages: 645-656
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model.2009
- Author(s)
  Susaki, E., K.Nakayama, L.Yamasaki, K.I.Nakayama
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 5192-5197
- Data Source
  KAKENHI-PROJECT-20370076
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model.2009
- Author(s)
  Susaki E, Nakayama K, Yamasaki L, Nakayama KI.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 5192-5197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] SCFβTrCP1 activates and ubiquitylates TAp63γ2008
- Author(s)
  Gallegos, J.R., Litersky, J., Lee, H., Sun, Y., Nakayama, K., Nakayama, K. and Lu, H.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 66-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] SCFβTrCP1 activates and ubiquitylates TAp63γ2008
- Author(s)
  Gallegos, J.R., Litersky, J., Lee, H., Sun, Y., Nakayama, K., Nakayama, K. and Lu, H.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 66-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell cycle arrest, and activation of autophagy.2008
- Author(s)
  Chen Q, Xie W, Kuhn DJ, Voorhees PM, Lopez-Girona A, Mendy D, Corral LG, Krenitsky VP, Xu W, Moutouh-de Parseval L, Webb DR, Mercurio F, Nakayama KI, Nakayama K. Orlowski RZ.
- Journal Title
  
  Blood 111
  
  Pages: 4690-4699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.2008
- Author(s)
  Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y,Hata A, Chiba S, Nakayama KI, Suda T.
- Journal Title
  
  Genes Dev. 22
  
  Pages: 986-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] The ubiquitinligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.2008
- Author(s)
  Qi J, Nakayama K, Gaitonde S, Goydos JS, Krajewski S, Eroshkin A, Bar-Sagi D, Bowtell D,Ronai Z.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 105
  
  Pages: 16713-16718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell cycle arrest, and activation of autophagy2008
- Author(s)
  Chen, Q., Xie, W., Kuhn, D.J., Voorhees, P.M., Lopez-Girona, A., Mendy, D., Corral, L.G., Krenitsky, V.P., Xu, W., Moutouh-de Parseval, L., Webb, D.R., Mercurio, F., Nakayama, K.I., Nakayama, K., Orlowski, R.Z.
- Journal Title
  
  Blood 111
  
  Pages: 4690-4699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Fbxw7 acts as a critical failsafe against premature loss of hematopoietic stem cells and development of T-ALL2008
- Author(s)
  Matsuoka, S., Oike, Y., Onoyama, I., Iwama, A., Arai, F., Takubo, K., Mashimo, Y., Oguro, H., Nitta, E., Ito, K., Miyamoto, K., Yoshiwara, H., Hosokawa, K., Nakamura, Y., Gomei, Y., Iwasaki, H., Hayashi, Y., Matsuzaki, Y., Nakayama, K., Ikeda, Y., Hata, A., Chiba, S., Nakayama, K.I., Suda, T.
- Journal Title
  
  Genes Dev. 22
  
  Pages: 986-991
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] SCF型ユビキチンリガーゼによる細胞周期制御と発癌2008
- Author(s)
  中山敬一 and 中山啓子
- Journal Title
  
  実験医学(増刊) 26
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-19657055
[Journal Article] Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition.2008
- Author(s)
  Song MS, Song Sj, Kim Sj, Nakayama K, Nakayama KI, Lim DS.
- Journal Title
  
  Oncogene 27
  
  Pages: 3176-3185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] SCF型ユビキチンリガーゼによる細胞周期制御と発癌2008
- Author(s)
  中山敬一and中山啓子
- Journal Title
  
  実験医学(増刊) 26
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-18013005
[Journal Article] The Role of {beta}-TrCP1 and {beta}-TrCP2 in Circadian Rhythm Generation by Mediating Degradation of Clock Protein PER2.2008
- Author(s)
  Ohsaki K, Oishi K, Kozono Y, Nakayama K, Nakayama KI, Ishida N.
- Journal Title
  
  J.Biochem. 144
  
  Pages: 609-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G(1)-S transition2008
- Author(s)
  Song, M.S., Song, S.J., Kim, S.J., Nakayama, K., Nakayama, K.I. and Lim, D.S.
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] SCF型ユビキチンリガーゼによる細胞周期制御と発癌2008
- Author(s)
  中山敬一and中山啓子
- Journal Title
  
  実験医学(増刊) 26
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-19044004
[Journal Article] Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7.2008
- Author(s)
  Ishikawa Y, Onoyama I, Nakayama KI, Nakayama K.
- Journal Title
  
  Oncogene 27
  
  Pages: 6164-6164
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell cycle arrest, and activation of autophagy2008
- Author(s)
  Chen, Q., Xie, W., Kuhn, D.J., Voorhees, P. M., Lopez-Girona, A., Mendy, D., Corral, L.G., Krenitsky, V.P., Xu, W., Moutouh-de Parseval, L., Webb, D. R., Mercurio, F., Nakayama, K.l., Nakayama, K., Orlowski, R. Z.
- Journal Title
  
  Blood 111
  
  Pages: 4690-4699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.2008
- Author(s)
  Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T.
- Journal Title
  
  Genes Dev 22
  
  Pages: 986-986
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] SCF TrCP1 activates and ubiquitylates TAp63gamma.2008
- Author(s)
  Gallegos JR, Litersky J, Lee H, Sun Y, Nakayama K, Lu H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 66-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] SCF型ユビキチンリガーゼによる細胞周期制御と発癌2008
- Author(s)
  中山敬一and中山啓子
- Journal Title
  
  実験医学(増刊) 26
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G(1)-S transition2008
- Author(s)
  Song, M.S., Song, S.J., Kim, S.J., Nakayama, K., Nakayama, K.I. and Lim, D.S.
- Journal Title
  
  Oncogene
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] SCF型ユビキチンリガーゼによる細胞周期制御と発癌2008
- Author(s)
  中山敬一 and 中山啓子
- Journal Title
  
  実験医学(増刊) 26
  
  Pages: 46-54
- Data Source
  KAKENHI-PLANNED-19057001
[Journal Article] Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7.2008
- Author(s)
  Ishikawa Y, Onoyama I, Nakayama KI Nakayama K.
- Journal Title
  
  Oncogene 27
  
  Pages: 6164-6174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570175
[Journal Article] T. Fbxw7 acts as a critical failsafe against premature loss of hematopoietic stem cells and development of T-ALL2008
- Author(s)
  Matsuoka, S., Oike, Y., Onoyama, I., Iwama, A., Arai, F., Takubo, K., Mashimo, Y., Oguro, H., Nitta, E., Ito, K., Miyamoto, K., Yoshiwara, H., Hosokawa, K., Nakamura, Y., Gomei, Y., Iwasaki, H., Hayashi, Y., Matsuzaki, Y., Nakayama, K., Ikeda, Y., Hata, A., Chiba, S., Nakayama, K.I., Suda, T.
- Journal Title
  
  Genes Dev 22
  
  Pages: 986-991
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells2007
- Author(s)
  Zhong, L., Georgia, S., Tschen, S.I., Nakayama, K., Nakayama, K.I., Bhushan, A.
- Journal Title
  
  J. Clin. Invest 117
  
  Pages: 2869-2876
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice2007
- Author(s)
  Suzuki, S., Fukasawa, H., Kitagawa, K., Uchida, C, Hattori, T., Isobe, T., Oda, T., Misaki, T., Ohashi, N., Nakayama, K., Nakayama, K.I., Hishida, A., Yamamoto, T., Kitagawa, M.
- Journal Title
  
  Am. J. Pathol. 171
  
  Pages: 473-483
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice2007
- Author(s)
  Shukla, A., Lounsbury, K. M., Barrett, T. F., Gell.J., Rincon, M., Butnor, K. J., Taatjes, D. J., Davis, G. S., Vacek, P., Nakayama, K. I., Nakayama K., Steele C, Mossman, B. T.
- Journal Title
  
  Am. J. Pathol. 170
  
  Pages: 140-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Skp2 controls adipocyte proliferation during the development of obesity2007
- Author(s)
  Sakai, T., Sakaue, H., Nakamura, T., Okada, M., Matsuki, Y., Watanabe, E., Hiramatsu, R., Nakayama, K., Nakayama, K.I. and Kasuga, M.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 2038-2046
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] The F Box Protein S Phase Kinase-associated Protein 2 Regulates Adipose Mass and Adipocyte Number in Vivo2007
- Author(s)
  Cooke, P. S., Holsberger, D. R., Cimafranca, M. A., Meling, D. D., Beals, C. M., Nakayama, K., Nakayama, K. I., Kiyokawa, H.
- Journal Title
  
  Obesity 15
  
  Pages: 1400-1408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells2007
- Author(s)
  Zhong, L., Georgia, S., Tschen, S.I., Nakayama, K., Nakayama, K.I., Bhushan, A.
- Journal Title
  
  J. Clin. Invest. 117
  
  Pages: 2869-2876
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice2007
- Author(s)
  Suzuki, S., Fukasawa, H., Kitagawa, K., Uchida, C, Hattori, T., Isobe, T., Oda, T., Misaki, T., Ohashi, N., Nakayama, K., Nakayama, K.I., Hishida, A., Yamamoto, T., Kitagawa, M.
- Journal Title
  
  Am. J. Pathol. 171
  
  Pages: 473-483
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] The F Box Protein S Phase Kinase-associated Protein 2 Regulates Adipose Mass and Adipocyte Number in Vivo2007
- Author(s)
  Cooke, P. S., Holsberger, D. R., Cimafranca, M. A., Meling, D. D., Beals, C. M., Nakayama, K., Nakayama, K. I., Kiyokawa, H.
- Journal Title
  
  Obesity 15
  
  Pages: 1400-1408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice2007
- Author(s)
  Shukla, A., Lounsbury, K. M., Barrett, T. F., Gell, J., Rincon, M., Butnor, K. J., Taatjes, D. J., Davis, G. S., Vacek, P., Nakayama, K. I., Nakayama K., Steele C., Mossman, B. T.
- Journal Title
  
  Am. J. Pathol. 170
  
  Pages: 140-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Protein kinase C-delta phosphorylates Ebp1 and prevents its proteolytic degradation, enhancing cell survival2007
- Author(s)
  Liu, Z., Liu, X., Nakayama, K. I., Nakayama, K., Ye, K.
- Journal Title
  
  J. Neurochem. 100
  
  Pages: 1278-1288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007
- Author(s)
  Miyamoto, K., Araki, K.Y., Naka, K., Arai, F., Takubo, K., Yamazaki, S., Matsuoka, S., Miyamoto, T., Ito, K., Ohmura, M., Chen, C., Hosokawa, K., Nakauchi, H., Nakayama, K., Nakayama, K.I., Harada, M., Motoyama, N., Suda, T. and Hirao, A.
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 101-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Ablation of p27 enhance kainate-induced seizure and hippocampal degeneration2007
- Author(s)
  Ueyama, C., Akashiba, H., Nakayama, K., Nakayama, K.I., Nishiyama, N., Matsuki, N.
- Journal Title
  
  Neuroreport 18
  
  Pages: 1781-1785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Noncanonical Wnt signaling through G protein-linked PKCδ activation promotes bone formation2007
- Author(s)
  Tu, X., Joeng, K.S., Nakayama, K.I., Nakayama, K., Rajagopal, J., Carroll, T.J., McMahon, A.P., Long, F.
- Journal Title
  
  Dev. Cell 12
  
  Pages: 113-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Davis. nPKC{varepsilon}, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells2007
- Author(s)
  Ehre, C, Y. Zhu, L. H. Abdullah, J. Olsen, K. I. Nakayama, K. Nakayama, R. O. Messing, C. W.
- Journal Title
  
  Am. J. Physiol. -Cell Physiol. 293
  
  Pages: 1445-1454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Negative feedback loop in the bim-caspase-3 axis regulating apoptosis and activity of osteoclasts2007
- Author(s)
  Wakeyama, H., Akiyama, T., Takahashi, K., Amano, H., Kadono, Y., Nakamura, M., Oshima, Y., Itabe, H., Nakayama, K.I., Nakayama, K., Nakamura, K. and Tanaka, S.
- Journal Title
  
  J. Bone. Miner. Res. 22
  
  Pages: 1631-1639
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis2007
- Author(s)
  Onoyama, l., R. Tsunematsu, A. Matsumoto, T. Kimura, I. M. de Alboran, K. Nakayama, K. l. Nakayama.
- Journal Title
  
  J. Exp. Med. 204
  
  Pages: 2875-2888
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] nPKC{varepsilon}, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells2007
- Author(s)
  Ehre, C, Y. Zhu, L. H. Abdullah, J. Olsen, K. I. Nakayama, K. Nakayama, R. O. Messing, C. W. Davis.
- Journal Title
  
  Am. J. Physiol.-Cell Physiol. 293
  
  Pages: 1445-1454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Ablation of p27 enhance kainate-induced seizure and hippocampal degeneration2007
- Author(s)
  Ueyama, C., Akashiba, H., Nakayama, K., Nakayama, K.I., Nishiyama, N., Matsuki, N.
- Journal Title
  
  Neuroreport 18
  
  Pages: 1781-1785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Cyclin D2 Translocates p27 out of the Nucleus and Promotes Its Degradation at the G0-G1 Transition2007
- Author(s)
  Susaki, E., Nakayama K., Nakayama, K. I.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 4626-4640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Negative feedback loop in the bim-caspase-3 axis regulating apoptosis and activity of osteoclasts2007
- Author(s)
  Wakeyama, H., Akiyama, T., Takahashi, K., Amano, H., Kadono, Y., Nakamura, M., Oshima, Y., Itabe, H., Nakayama, K.I., Nakayama, K., Nakamura, K. and Tanaka, S.
- Journal Title
  
  J. Bone. Miner. Res. 22
  
  Pages: 1631-1639
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex2007
- Author(s)
  Itoh, Y., Masuyama, N., Nakayama, K., NakayamaK. I., Gotoh, Y.
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 390-396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Protein kinase C-delta phosphorylates Ebp1 and prevents its proteolytic degradation, enhancing cell survival2007
- Author(s)
  Liu, Z., Liu, X., Nakayama, K. I., Nakayama, K., Ye, K.
- Journal Title
  
  J. Neurochem. 100
  
  Pages: 1278-1288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Noncanonical Wnt signaling through G protein-linked PKCδactivation promotes bone formation2007
- Author(s)
  Tu, X., Joeng, K.S., Nakayama, K.I., Nakayama, K., Rajagopal, J., Carroll, T.J., McMahon, A.P., Long, F.
- Journal Title
  
  Dev. Cell 12
  
  Pages: 113-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007
- Author(s)
  Miyamoto, K., Araki, K.Y., Naka, K., Arai, F., Takubo, K., Yamazaki, S., Matsuoka, S., Miyamoto, T., Ito, K., Ohmura, M., Chen, C, Hosokawa, K., Nakauchi, H., Nakayama, K., Nakayama, K.I., Harada, M., Motoyama, N., Suda, T. and Hirao, A.
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 101-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Skp2 controls adipocyte proliferation during the development of obesity2007
- Author(s)
  Sakai, T., Sakaue, H., Nakamura, T., Okada, M., Matsuki, Y., Watanabe, E., Hiramatsu, R., Nakayama, K., Nakayama, K.I. and Kasuga, M.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 2038-2046
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex2007
- Author(s)
  Itoh, Y., Masuyama, N., Nakayama, K., NakayamaK. I., Gotoh, Y.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 390-396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis2007
- Author(s)
  Onoyama, I., R. Tsunematsu, A. Matsumoto, T. Kimura, I. M. de Alboran, K. Nakayama, K. I. Nakayama
- Journal Title
  
  J. Exp. Med 204
  
  Pages: 2875-2888
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Cyclin D2 Translocates p27 out of the Nucleus and Promotes Its Degradation at the G0-G1 Transition2007
- Author(s)
  Susaki, E., Nakayama K., Nakayama, K. I.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 4626-4640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] PKCdelta is necessary for Smad3 expression and transforming growth factorbeta-induced fibronectin synthesis in vascular smooth muscle cells.2006
- Author(s)
  Ryer, E.J., Hom, R.P., Sakakibara, K., Nakayama, K.I., Nakayama, K., Faries, P.L., Liu, B., Kent, K.C.
- Journal Title
  
  Arterioscler.Thromb.Vase.Biol. 26
  
  Pages: 780-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCδ-dependent pathway in murine lung2006
- Author(s)
  Shukla, A., Barrett, T.F., Nakayama, K.I., Nakayama, K., Mossman, B.T. and Lounsbury, K.M.
- Journal Title
  
  FASEB J. 20
  
  Pages: 997-999
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Double knockout mice show BASH and PKC8 have different epistatic relationships in B cell maturation and CD40-mediated activation2006
- Author(s)
  Nojima, T., Hayashi, K., Goitsuka, R., Nakayama, K., Nakayama, Kl., Kitamura, D.
- Journal Title
  
  Immunol. Lett. 105
  
  Pages: 48-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] PKCdelta is necessary for Smad3 expression and transforming growth factorbeta-induced fibronectin synthesis in vascular smooth muscle cells2006
- Author(s)
  Ryer, E. J., Hom, R. P., Sakakibara, K., Nakayama, K. I., Nakayama, K., Faries, P. L, Liu, B., Kent, K. C.
- Journal Title
  
  Arterioscler. Thromb. Vase. Biol. 26
  
  Pages: 780-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice2006
- Author(s)
  Fotovati, A., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  CellDiv. 1
  
  Pages: 4-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCδ-dependent pathway in murine lung2006
- Author(s)
  Shukla, A., Barrett, T.F., Nakayama, K.I., Nakayama, K., Mossman, B.T. and Lounsbury, K.M.
- Journal Title
  
  FASEB J. 20
  
  Pages: 997-999
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Double knockout mice show BASH and PKCδhave different epistatic relationships in B cell maturation and CD40-mediated activation2006
- Author(s)
  Nojima, T., Hayashi, K., Goitsuka, R., Nakayama, K., Nakayama, K.l., Kitamura, D.
- Journal Title
  
  Immunol. Lett. 105
  
  Pages: 48-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Geminin is essential for the development of preimplantation mouse embryos2006
- Author(s)
  Hara, K., Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1281-1293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis2006
- Author(s)
  Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z., Nishimoto, T.
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Ubiquitin ligases controlling cell cycle and cancer.2006
- Author(s)
  Nakayama, K.I., et. al.
- Journal Title
  
  Nat. Rev. Cancer 6
  
  Pages: 369-381
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinomacell invasiveness and metastasis2006
- Author(s)
  Gao, Y., Kitagawa, K., Hiramatsu, Y., Kikuchi, H., Isobe, T., Shimada, M., Uchida, C, Hattori, T., Oda, T., Nakayama, K., Nakayama, K.I., Tanaka, T., Konno, H., Kitagawa, M.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 11623-11631
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice2006
- Author(s)
  Fotovati, A., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Cell Div. 1
  
  Pages: 4-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners.2006
- Author(s)
  Iwanaga, R., Komori, H., Ishida, S., Okamura, N., Nakayama, K., Nakayama, K.I., Ohtani, K.
- Journal Title
  
  Oncogene 25
  
  Pages: 1786-1798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells2006
- Author(s)
  Parcellier, A., Brunet, M., Schmitt, E., Col, E., Didelot, C, Hammann, A., Nakayama, K., Nakayama, Kl., Khochbin, S., Solary, E.., Garrido, C.
- Journal Title
  
  FASEB J. 20
  
  Pages: 1179-1181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells2006
- Author(s)
  Parcellier, A., Brunet, M., Schmitt, E., Col, E., Didelot, C., Hammann, A., Nakayama, K., Nakayama, KI., Khochbin, S., Solary, E.., Garrido, C.
- Journal Title
  
  FASEB J. 20
  
  Pages: 1179-1181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis2006
- Author(s)
  Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C, Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z., Nishimoto, T.
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence through activating ROS/PKC-5 signalling pathway2006
- Author(s)
  Takahashi, A., Ohtani, N., Yamakoshi, K., lida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] PKCδ regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation2006
- Author(s)
  Pula, G., Schuh, K., Nakayama K., Nakayama, K. I., Walter, U., Poole, A. W.
- Journal Title
  
  Blood 108
  
  Pages: 4035-4044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.2006
- Author(s)
  Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K.I., Nakayama, K., Fujita, M., Lygerou, Z., Nishimoto, T.
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Ubiquitin ligases controlling cell cycle and cancer.2006
- Author(s)
  Nakayama, K. I., et. al.
- Journal Title
  
  Nat. Rev. Cancer 6
  
  Pages: 369-381
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Suppression of centrosome amplification after DNA damage depends on p27 accumulation2006
- Author(s)
  Sugihara, E., Kanai, M., Saito, S., Nitta, T., Toyoshima, H., Nakayama, K., Nakayama, K.I., Fukasawa, K., Schwab, M., Saya, H., Miwa, M.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 4020-4029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Geminin is essential for the development of preimplantation mouse embryos2006
- Author(s)
  Hara, K., Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1281-1293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Ubiquitin ligases controlling cell cycle and cancer2006
- Author(s)
  Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Nat. Rev. Cancer 6
  
  Pages: 369-381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] PKCδ regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation2006
- Author(s)
  Pula, G., Schuh, K., Nakayama K., Nakayama, K. I., Walter, U., Poole, A. W.
- Journal Title
  
  Blood 108
  
  Pages: 4035-4044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] PKCdelta is necessary for Smad3 expression and transforming growth factorbeta-induced fibronectin synthesis in vascular smooth muscle cells2006
- Author(s)
  Ryer, E. J., Horn, R. P., Sakakibara, K., Nakayama, K. I., Nakayama, K., Faries, P. L, Liu, B., Kent, K. C.
- Journal Title
  
  Arterioscler. Thromb. Vase. Biol. 26
  
  Pages: 780-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Suppression of centrosome amplification after DNA damage depends on p27 accumulation2006
- Author(s)
  Sugihara, E., Kanai, M., Saito, S., Nitta, T., Toyoshima, H., Nakayama, K., Nakayama, K.I., Fukasawa, K., Schwab, M., Saya, H., Miwa, M.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 4020-4029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners2006
- Author(s)
  Iwanaga, R., Komori, H., Ishida, S., Okamura, N., Nakayama, K., Nakayama, K. I., Ohtani, K.
- Journal Title
  
  Oncogene 25
  
  Pages: 1786-1798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence through activating ROS/PKC-δsignalling pathway2006
- Author(s)
  Takahashi, A., Ohtani, N., Yamakoshi, K., lida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners2006
- Author(s)
  Iwanaga, R., Komori, H., Ishida, S., Okamura, N., Nakayama, K., Nakayama, K. I., Ohtani, K.
- Journal Title
  
  Oncogene 25
  
  Pages: 1786-1798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Journal Article] Ubiquitin ligases controlling cell cycle and cancer2006
- Author(s)
  Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Nat. Rev. Cancer 6
  
  Pages: 369-381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis2006
- Author(s)
  Gao, Y., Kitagawa, K., Hiramatsu, Y., Kikuchi, H., Isobe, T., Shimada, M., Uchida, C, Hattori, T., Oda, T., Nakayama, K., Nakayama, K.I., Tanaka, T., Konno, H., Kitagawa, M.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 11623-11631
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Journal Article] Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury.2005
- Author(s)
  He, C.H., Waxman, A.B., Lee, C.G., Link, H., Rabach, M.E., Ma, B., Chen, Q., Zhu, Z., Zhong, M., Nakayama, K., Nakayama, K.I., Homer, R., Elias, J.A.
- Journal Title
  
  J.Clin.Invest. 115
  
  Pages: 1039-1048
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.2005
- Author(s)
  Rodier, G., Makris, C., Coulombe, P., Scime, A., Nakayama, K., Nakayama, K.I., Meloche, S.
- Journal Title
  
  J.Cell Biol. 168
  
  Pages: 55-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.2005
- Author(s)
  Jiang, H., Chang, F.-C., Ross, A.E., Lee, J., Nakayama, K.I., Nakayama, K., Desiderio, S.
- Journal Title
  
  Mol.Cell 18
  
  Pages: 699-709
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Suppression of cell migration by protein kinase Cdelta.2005
- Author(s)
  Jackson, D., Zheng, Y., Lyo, D., Shen, Y., Nakayama, K., Nakayama, K.I., Humphries, M.J., Reyland, M.E., Foster, D.A.
- Journal Title
  
  Oncogene. 24
  
  Pages: 3067-3072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Mammalian E4 is required for cardiac development and maintenance of the nervous system.2005
- Author(s)
  Kaneko-Oshikawa, C., Nakagawa, T., Yamada, M., Yoshikawa, H., Matsumoto, M., Yada, M., Hatakeyama, S., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 10953-10964
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation.2005
- Author(s)
  Kotake, Y., Nakayama, K., Ishida, N., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 1095-1102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.2005
- Author(s)
  Kase, S., Nakayama, K.I., Nakayama, K., Ikeda, H., Harada, T., Harada, C., Ohgami, K., Shiratori, K., Ohno, S., Yoshida, K.
- Journal Title
  
  Int.J.Mol.Med. 16
  
  Pages: 257-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Molecular dissection of the interaction between p27 and KPC, the ubiquitinligase that regulates proteolysis of p27 in G1 phase.2005
- Author(s)
  Kotoshiba, S., Kamura, T., Hara, T., Ishida, N., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 17694-17700
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens.2005
- Author(s)
  Kase, S., Ikeda, H., Harada, T., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Nakayama, K.I., Nakayama, K., Ohno, S., Yoshida, K.
- Journal Title
  
  Curr.Eye Res. 30
  
  Pages: 437-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Skp2-mediated degradation of p27 regulates into mitosis.2004
- Author(s)
  Nakayama, K., Nagahama, H., Minamishima, Y.A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., Iemura, S., Natsume, T., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Involvement of p27KIP1 in the proliferation of the developing corneal endothelium.2004
- Author(s)
  Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ilieva, I.B., Ohno, S., Nishi, S., Nakayama, K.I.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 45
  
  Pages: 2163-2167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K. et al.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16022204
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al.Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K. et al.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase.2004
- Author(s)
  Tokarz, S., Berset, C., La Rue, J., Friedman, K., Nakayama, K.I., Nakayama, K., Zhang, D.E., Lanker, S.
- Journal Title
  
  J.Biol Chem. 279
  
  Pages: 46424-46430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Mouse Fbw7/Sel-10/Cdc4 is required for Notch degradation during vascular development.2004
- Author(s)
  Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 9417-9423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27^<Kip1> at G1 phase.2004
- Author(s)
  Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Nat.Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.2004
- Author(s)
  Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S., Nakayama, K.I.
- Journal Title
  
  Graefes Arch.Clin.Exp.Ophthalmol 242
  
  Pages: 437-441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Early embryonic death in mice lacking the beta-catenin-binding protein Duplin.2004
- Author(s)
  Nishiyama, M., Nakayama, K., Tsunematsu, R., Tsukiyama, T., Kikuchi, A., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 8386-8394
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27^<Kip1> at G1 phase.2004
- Author(s)
  Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F, Nakayama, K., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body.2004
- Author(s)
  Yoshida, K., Nakayama, K., Kase, S., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S., Nishi, S., Nakayama, K.I.
- Journal Title
  
  Anat.Embryol 208
  
  Pages: 145-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containin E3 ligase.2004
- Author(s)
  Oh, K.J., Kalinina, A., Wang, J., Nakayama, K., Nakayama, K.I., Bagchi, S.
- Journal Title
  
  J.Virol. 78
  
  Pages: 5338-5346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Early embryonic death in mice lacking the β-catenin-binding protein Duplin.2004
- Author(s)
  Nishiyama, K.et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 8386-8394
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K. et al.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis.2004
- Author(s)
  Nakayama K et al.
- Journal Title
  
  Dev Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16590217
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M., et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K.et al., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M., Yada, M., Hatakeyama, S., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta.2004
- Author(s)
  Li, B., Wang, X., Rasheed, N., Hu, Y., Boast, S., Ishii, T., Nakayama, K., Nakayama, K.I., Goff, S.P.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 1824-1837
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370084
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K., Nagahama, H., Minamishima, Y.A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., lemura, S., Natsume, T., Nakayama, K.I.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K. et al.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16026202
[Journal Article] Phosphorylation-dependent degradiation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.2003
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 5
  
  Pages: 28-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Patent] 小細胞肺がんの治療2022
- Inventor(s)
  中山　敬一
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-158382
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 相互作用推定方法、相互作用推定装置および相互作用推定プログラム2021
- Inventor(s)
  中山敬一, 清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-091667
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法2019
- Inventor(s)
  中山敬一、清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法2018
- Inventor(s)
  中山敬一、清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-157870
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] ＦＯＸＫ１阻害剤を含有する組成物及びＦＯＸＫ１阻害作用を有する候補物質のスクリーニング方法2018
- Inventor(s)
  中山敬一
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-185599
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 血糖調節障害の予防・治療剤,及びそれらのスクリーニング方法2004
- Inventor(s)
  中山敬一他3名
- Industrial Property Rights Holder
  神戸大学, 長野上智行
- Industrial Property Number
  2004-037439
- Filing Date
  2004-02-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Patent] 心筋細胞の増殖方法2003
- Inventor(s)
  中山敬一他2名
- Industrial Property Rights Holder
  第一サントリーファーマ株式会社
- Industrial Property Number
  2003-391708
- Filing Date
  2003-11-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Presentation] The mechanism and functional significance of fibulin 2 alternative splicing in the progression of colorectal cancer2023
- Author(s)
  Y Wang R Funayama K Nakayama
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02458
[Presentation] AI創薬プラットフォームLIGHTHOUSEによる創薬革命2023
- Author(s)
  中山　敬一
- Organizer
  第443回情報計算化学生物学会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Collagen XVIIはCXCL10/CXCR3の免疫応答経路を介して膵癌腫瘍形成を抑制する2023
- Author(s)
  柏木良介, 舟山亮, 青木修一, 平野直大, 安藤未佳, 井上亨悦, 伊関雅裕, 三浦孝之, 石田晶玄, 大塚英郎, 水間正道, 中川圭, 森川孝則, 亀井尚, 海野倫明, 中山啓子
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K08816
[Presentation] 次世代プロテオミクスが拓く医学生物学の新地平：100年来のがんの謎を解く2022
- Author(s)
  中山　敬一
- Organizer
  第64回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 細胞周期阻害分子p57が織りなす幹細胞科学：がん幹細胞の撲滅に向けて2022
- Author(s)
  中山　敬一
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 近未来のライフサイエンス：人工知能によるデータ駆動型サイエンスの時代へ2022
- Author(s)
  中山　敬一
- Organizer
  第95回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 小細胞肺がんの二つのプリン合成経路を標的とする治療法の開発2022
- Author(s)
  中山　敬一
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Life sciences in the near future: Towards an era of data-driven sciences with artificial intelligence2022
- Author(s)
  Nakayama KI, Matsumoto M
- Organizer
  The 30th Hot Spring Harbor International Symposium: New technologies meet Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 人工知能によるがん研究2022
- Author(s)
  中山　敬一
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] これからの生命科学研究：オミクスから人工知能まで2021
- Author(s)
  中山敬一
- Organizer
  東日本研究医養成プログラム　第11回「夏のリトリート」
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん幹細胞の撲滅による新しいがん治療法2021
- Author(s)
  中山敬一
- Organizer
  第一回日本放射線影響学会・若手部会　放射線影響研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 第二のワールブルグ効果：がんにおけるグルタミン由来窒素代謝の変化2021
- Author(s)
  中山敬一
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] マイクロエクソンの選択的スプライシングは大腸がん細胞の転移を制御する2021
- Author(s)
  舟山亮, 望月保志, 城田松之, 菊川柚奈, 大平優丈, 中山啓子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02458
[Presentation] がん幹細胞における細胞周期制御：がん撲滅のための治療標的としての期待2020
- Author(s)
  中山敬一
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 次世代プロテオミクスが拓く医学生物学の新地平：90年来のがんの謎を解く2020
- Author(s)
  中山敬一
- Organizer
  第9回生命医薬情報学連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] グルタミンからの窒素代謝の変化はがんの悪性進化に必須である：”第二のワールブルグ効果”の発見2020
- Author(s)
  中山敬一
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 近未来のがん研究：オミクスと人工知能によるデータドリブン科学の時代.2019
- Author(s)
  中山　敬一
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 知的障害・自閉症関連因子SETD5によるrDNAのエピジェネティック制御2019
- Author(s)
  中川直,中山啓子
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] 蛋白分解異常による新規筋萎縮性側索硬化症の発症機構2019
- Author(s)
  渡辺靖章, 中川直, 鈴木直輝, 割田仁, 中山啓子, 青木正志
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] Alternative Splicing of FBLN2 generates two proteins with different N-linked glycosylation patterns2019
- Author(s)
  Wei,Chen Kao,Ryo Funayama, Keiko Nakayama
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] 蛋白分解異常による新規筋萎縮性側索硬化症の発症機構2019
- Author(s)
  渡辺靖章, 中川直, 鈴木直輝, 割田仁, 中山啓子, 青木正志
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism: Discovery of the "second" Warburg effect2019
- Author(s)
  Keiichi I. Nakayama
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 知的障害・自閉症関連因子SETD5によるrDNAのエピジェネティック制御2019
- Author(s)
  中川直, 中山啓子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] 知的障害・自閉症関連因子SETD5によるrDNAのエピジェネティック制御2019
- Author(s)
  中川直, 中山啓子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] 蛋白分解異常による新規筋萎縮性側索硬化症の発症機構2019
- Author(s)
  渡辺靖章, 中川直, 鈴木直輝, 割田仁, 中山啓子, 青木正志
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] 次世代プロテオミクスが拓くがん研究の新時代：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Alternative Splicing of FBLN2 generates two proteins with different N-linked glycosylation patterns2019
- Author(s)
  Wei Chen,Ryo Funayama, Keiko Nakayama
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] A metabolic shift in nitrogen flux from glutamine contributes to malignant progression of cancer: Discovery of the SECOND Warburg effect.2019
- Author(s)
  Nakayama, K. I., Kodama, M., Matsumoto, M.
- Organizer
  Cell Symposia: Hallmarks of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 次世代プロテオミクスによって明らかとなったがん代謝ダイナミクス：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Alternative Splicing of FBLN2 generates two proteins with different N-linked glycosylation patterns2019
- Author(s)
  Wei Chen Kao,Ryo Funayama, Keiko Nakayama
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism: Discovery of the "second" Warburg effect.2019
- Author(s)
  Nakayama, K. I.
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 7th Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん代謝における窒素利用シフト：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] ユビキチン化によるFACT複合体の機能制御2018
- Author(s)
  中川直、諸星茜、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] 鉄代謝制御を司るユビキチンシステムと疾患2018
- Author(s)
  中山敬一
- Organizer
  第42回鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 大腸がんにおけるFibulin2スプライスバリアントの役割2018
- Author(s)
  舟山亮、遠山慎吾、高唯真、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] 人工知能を用いたスコアシステムは乳がん患者の予後を正確に予測する2018
- Author(s)
  中山敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Mutation of cyclin F may contribute to Amyotrophic Lateral Sclerosis pathogensis by affecting VCP ATPase activity2018
- Author(s)
  Yujao Yu, Akane Morohoshi, Tadashi Nakagawa, Keiko Nakayama
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] 転移巣にTAMを呼び寄せるメカニズムとそれを阻害する既存薬2018
- Author(s)
  中山敬一
- Organizer
  第16回がんとハイポキシア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん幹細胞における細胞周期制御2018
- Author(s)
  中山敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] ユビキチン化によるFACT複合体の機能制御2018
- Author(s)
  中川直、諸星茜、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] 大腸がんにおけるFibulin2スプライスバリアントの役割2018
- Author(s)
  舟山亮、遠山慎吾、高唯真、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] Mutation of cyclin F may contribute to Amyotrophic Lateral Sclerosis pathogensis by affecting VCP ATPase activity2018
- Author(s)
  Yujao Yu, Akane Morohoshi, Tadashi Nakagawa, Keiko Nakayama
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04035
[Presentation] グルタミンからの窒素流束の代謝シフトはがん悪性化に必要である：第二のワールブルグ効果の発見2018
- Author(s)
  中山敬一
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Mutation of cyclin F may contribute to Amyotrophic Lateral Sclerosis pathogensis by affecting VCP ATPase activity2018
- Author(s)
  Yujao Yu, Akane Morohoshi, Tadashi Nakagawa, Keiko Nakayama
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19281
[Presentation] ユビキチン化によるFACT複合体の機能制御2018
- Author(s)
  中川直、諸星茜、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] c-Mycによって統合されるがん代謝ネットワークの全貌2018
- Author(s)
  中山敬一
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 大腸がんにおけるFibulin2スプライスバリアントの役割2018
- Author(s)
  舟山亮、遠山慎吾、高唯真、中山啓子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04795
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism2017
- Author(s)
  Nakayama Keiichi I.
- Organizer
  The 1st International Symposium for Trans-Omics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Fbxw7 is essential for quiescence and drug resistance in cancer stem cell2017
- Author(s)
  Nakayama Keiichi I.
- Organizer
  Cullin RING ligases and Protein Neddylation: Biology and Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 次世代プロテオミクスによる「第二のワールブルグ効果」の発見2017
- Author(s)
  中山敬一
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Reactivation of cell proliferation by continuous TGF-β　treatment2016
- Author(s)
  Tadashi Nakagawa, Masaki Hosogane, Ryo Funayama, Keiko Nakayama
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18453
[Presentation] 大腸がんにおけるタンパク質シトルリン化酵素PADI2の役割2016
- Author(s)
  舟山亮、谷口肇、水間正道、藤島史喜、小林実、大沼忍、海野倫明、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] Molecular analysis of Amyotrophic Lateral Sclerosis associated Cyclin F mutants.2016
- Author(s)
  Yujiao Yu, Akane Morohoshi, Tadashi Nakagawa, Keiko Nakayama.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] H3K27ヒストン修飾によるエンハンサー制御のゲノムワイド解析2016
- Author(s)
  細金正樹、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] ユビキチン化によるFACT複合体の機能制御2016
- Author(s)
  諸星茜、中川直、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] 大腸がんにおけるタンパク質シトルリン化酵素PADI2の役割2016
- Author(s)
  舟山亮、谷口肇、水間正道、藤島史喜、小林実、大沼忍、海野倫明、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] 大腸癌で発現が抑制されるPeptidylarginine deiminase2の機能解析2016
- Author(s)
  谷口肇、舟山亮、小林実、高館達之、阿部友哉、水間正道、藤島史喜、大沼忍、内藤剛、海野倫明、中山啓子
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] ユビキチン化によるFACT複合体の機能制御2016
- Author(s)
  諸星茜、中川直、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] Cell cycle regulation in cancer stem cell2016
- Author(s)
  Nakayama, K. I.
- Organizer
  The 47th International Symposium of The Princess Takamatsu Cancer Research Fund: Current status and perspectiveof cancer stem cell research
- Place of Presentation
  東京
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 静止期維持因子p57は+4ポジション幹細胞の制御を介して腸管上皮の恒常性を維持する2016
- Author(s)
  比嘉綱己, 沖田康孝, 松本有樹修, 武石昭一郎, 中津海洋一, 中山敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Reactivation of cell proliferation by continuous TGF-β　treatment.2016
- Author(s)
  Tadashi Nakagawa, Masaki Hosogane, Ryo Funayama, Keiko Nakayama.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] Molecular analysis of Amyotrophic Lateral Sclerosis associated Cyclin F mutants.2016
- Author(s)
  Yujiao Yu, Akane Morohoshi, Tadashi Nakagawa, Keiko Nakayama.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] 大腸癌で発現が抑制されるPeptidylarginine deiminase2の機能解析2016
- Author(s)
  谷口肇、舟山亮、小林実、高館達之、阿部友哉、水間正道、藤島史喜、大沼忍、内藤剛、海野倫明、中山啓子
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] Cell cycle regulation in cancer stem cell2016
- Author(s)
  Nakayama, K. I.
- Organizer
  The Cell Cycle from Mechanism to Therapy
- Place of Presentation
  トロント
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] H3K27ヒストン修飾によるエンハンサー制御のゲノムワイド解析2016
- Author(s)
  細金正樹、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K18453
[Presentation] Large-scale targeted proteomics unveils a global landscape of cancer metabolism2016
- Author(s)
  Keiichi Nakayama
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthrough in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, USA
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 造血幹細胞の機能維持におけるユビキチンリガーゼFBXL5による鉄代謝制御の重要性2016
- Author(s)
  武藤義治, 西山正章, 仁田暁大, 諸石寿朗, 中山敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] H3K27ヒストン修飾によるエンハンサー制御のゲノムワイド解析2016
- Author(s)
  細金正樹、中山啓子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K14664
[Presentation] Reactivation of cell proliferation by continuous TGF-β　treatment.2016
- Author(s)
  Tadashi Nakagawa, Masaki Hosogane, Ryo Funayama, Keiko Nakayama.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] 次世代プロテオミクスが解き明かす生命システムの全体像2015
- Author(s)
  中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] がん原遺伝子RASによる遺伝子サイレンシングの分子機構の解析2015
- Author(s)
  舟山亮、細金正樹、長嶋剛史、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] がん原遺伝子RASによる遺伝子サイレンシングの分子機構の解析2015
- Author(s)
  舟山亮、細金正樹、長嶋剛史、中山啓子.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18453
[Presentation] がん原遺伝子RASによる遺伝子サイレンシングの分子機構の解析.2015
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子.
- Organizer
  第38回日本分子生物学会年会.
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830064
[Presentation] p57は静止状態の腸管幹細胞を制御することで腸管上皮の恒常性を維持する2015
- Author(s)
  比嘉綱己, 沖田康孝, 松本有樹修, 武石昭一郎, 中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] TGF-β刺激によるTFIID構成因子TAF7の分解とその役割の解明2015
- Author(s)
  中川直、細金正樹、舟山亮、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15024
[Presentation] TGF-β刺激によるTFIID構成因子TAF7の分解とその役割の解明. 第38回日本分子生物学会年会.2015
- Author(s)
  中川直, 細金正樹, 舟山亮, 中山啓子.
- Organizer
  第38回日本分子生物学会年会.
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830064
[Presentation] セルトリ細胞特異的β-TrCPノックアウトマウスの解析2015
- Author(s)
  諸星茜、中川直、中野星児、中山啓子.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] セルトリ細胞特異的β-TrCPノックアウトマウスの解析2015
- Author(s)
  諸星茜、中川直、中野星児、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15024
[Presentation] TGF-β刺激によるTFIID構成因子TAF7の分解とその役割の解明2015
- Author(s)
  中川直、細金正樹、舟山亮、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18453
[Presentation] がん原遺伝子RASによる遺伝子サイレンシングの分子機構の解析2015
- Author(s)
  舟山亮、細金正樹、長嶋剛史、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15024
[Presentation] TGF-β刺激によるTFIID構成因子TAF7の分解とその役割の解明2015
- Author(s)
  中川直、細金正樹、舟山亮、中山啓子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] TFIID complex changes accompany epithelial-mesenchymal transition (EMT).2014
- Author(s)
  Nakagawa, Tadashi & Nakayama, Keiko
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] 癌幹細胞の理解と制御：癌を完治させる治療戦略2014
- Author(s)
  中山敬一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] H3K27me3修飾パターン形成過程の時系列解析2014
- Author(s)
  細金正樹, 舟山亮, 城田松之 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26670085
[Presentation] がん遺伝子による転写変化とエピゲノム変化2014
- Author(s)
  中山啓子
- Organizer
  第23回長崎障害者支援再生医療研究会
- Place of Presentation
  長崎大学医学部良順会館（長崎県長崎市）
- Year and Date
  2014-11-04
- Invited
- Data Source
  KAKENHI-PROJECT-26670085
[Presentation] H3K27me3修飾パターン形成過程の時系列解析2014
- Author(s)
  細金正樹, 舟山亮, 城田松之 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction on leukemia stem cells through altered microenvironmental regulation2014
- Author(s)
  Takeishi, S., Matsumoto, A., Nakayama, K. I.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-05-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 精子形成におけるE3ユビキチンリガーゼβ-TrCPの新規基質の同定と解析2014
- Author(s)
  久志瞭, 中川直, 中野星児, 遠藤尚博 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26670085
[Presentation] がん遺伝子による転写変化とエピゲノム変化2014
- Author(s)
  中山啓子
- Organizer
  第23回長崎障害者支援再生医療研究会
- Place of Presentation
  長崎大学医学部良順会館（長崎県長崎市）
- Year and Date
  2014-11-04
- Invited
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] マウスES細胞におけるgemininの細胞周期と分化に対する制御2014
- Author(s)
  福本恵美子, Kundu, Lena Rani, 佐藤聡一郎, 細金正樹 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26670085
[Presentation] H3K27me3修飾パターン形成過程の時系列解析.2014
- Author(s)
  細金正樹, 舟山亮, 城田松之,中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26830064
[Presentation] マウスES細胞におけるgemininの細胞周期と分化に対する制御.2014
- Author(s)
  福本恵美子, Kundu, Lena Rani, 佐藤聡一郎, 細金正樹 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] 精子形成におけるE3ユビキチンリガーゼβ-TrCPの新規基質の同定と解析2014
- Author(s)
  久志瞭, 中川直, 中野星児, 遠藤尚博 & 中山啓子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26293059
[Presentation] TFIID complex changes accompany epithelial-mesenchymal transition (EMT)2014
- Author(s)
  Nakagawa, Tadashi & Nakayama, Keiko
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26670085
[Presentation] Deep and absolute quantification of human proteome unveils a global landscape of cancer metabolism2014
- Author(s)
  Nakayama, K. I.
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-11-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] ユビキチンリガーゼFBXL5による鉄代謝制御とその破綻2014
- Author(s)
  中山敬一
- Organizer
  第38回鉄バイオサイエンス学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Fbw7 is essential for maintenance of quiescence and function of cancer stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  35th Naito Conference
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2013-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Fbw7 is essential for maintenance of quiescence and function of cancer stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  The 23rd Hot Spring Harbor Symposium: Recent Advances in Stem Cell Biology 2013
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2013-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] がん治療におけるFbxw7抑制の二面性：光と影2013
- Author(s)
  中山敬一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Cell cycle and cancer stem cells: Abrogation of quiescence by Fbw7 ablation eliminates leukemia stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  ISEH 42nd Annual Scientific Meeting
- Place of Presentation
  Vienna, Austria
- Year and Date
  2013-08-23
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] What is the Warburg effect? Next-generation proteomics uncovers the secret of cancer2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Year and Date
  2013-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Geminin deletion in hematopoietic stem cells promotes differentiation of megakaryocytes and platelets.2011
- Author(s)
  Seiji Nakano, Yousuke Sasaki, Hozumi Motohashi, Keiko Nakayama
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Geminin deletion in hematopoietic stem cells promotes differentiation of megakaryocytes and platelets.2011
- Author(s)
  中野星児, 佐々木陽丞, 本橋ほづみ, 中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ras-mediated regional silencing around Fas gene locus.2011
- Author(s)
  Masaki Hosogane, Ryo Funayama, Yuichiro Nishida, Keiko Nakayama
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Geminin deletion in hematopoietic stem cells promotes differentiation of megakaryocytes and platelets.2011
- Author(s)
  Seiji Nakano, Yousuke Sasaki, Hozumi Motohashi, Keiko Nakayama
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Winter Camp of GCOE 2011 ～The Cultivation of New Generation of Scientists～ Tohoku University Global COE for Conquest of Singal Transcuction Dieseases with "Network Medicine"2011
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 中山啓子
- Organizer
  Ras-mediated regional silencing around Fas gene locus
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ras-mediated regional silencing around Fas gene locus.東北大学グローバルCOE Network Medicine創生拠点2011
- Author(s)
  Masaki Hosogane, Ryo Funayama, Yuichiro Nishida, Keiko Nakayama
- Organizer
  冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ras-mediated regional silencing around Fas gene locus.2011
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ras-mediated regional silencing around Fas gene locus.2011
- Author(s)
  Masaki Hosogane, Ryo Funayama, Yuichiro Nishida, Keiko Nakayama
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Geminin deletion in hematopoietic stem cells promotes differentiation of megakaryocytes and platelets.2011
- Author(s)
  Seiji Nakano, Yousuke Sasaki, Hozumi Motohashi, Keiko Nakayama
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2011
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Winter Camp of GCOE 2011 ～The Cultivation of New Generation of Scientists～ Tohoku University Global COE for Conquest of Singal Transcuction Dieseases with "Network Medicine"2011
- Author(s)
  中野星児, 佐々木陽丞, 本橋ほずみ, 中山啓子
- Organizer
  Geminin deletion in hematopoietic stem cells promotes differentiation of megakaryocytes and platelets
- Place of Presentation
  仙台
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ras-mediated gene silencingによるFas遺伝子領域のエピジェネティック制御2010
- Author(s)
  細金正樹、舟山亮、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Geminin negatively regulates thrombopoiesis2010
- Author(s)
  Keiko Nakayama
- Organizer
  MEXT Priority Research Project "Cell Proliferation Control" International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 第33回分子生物学会年会・第83回日本生化学会大会合同大会2010
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 中山啓子
- Organizer
  Ras-mediated gene silencingによるFas遺伝子領域のエピジェネティック制御
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ras-mediated gene silencingによるFas遺伝子領域のエピジェネティック制御2010
- Author(s)
  細金正樹、舟山亮、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Geminin negatively regulates thrombopoiesis2010
- Author(s)
  Keiko Nakayama
- Organizer
  MEXT Priority Research Project "Cell Proliferation Control" International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Ras-mediated gene silencing によるFas遺伝.f領域のエピジェネティック制御2010
- Author(s)
  細金正樹、舟山亮、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Geminin negatively regulates thromhopoiesis2010
- Author(s)
  Keiko Nakayama
- Organizer
  MEXT Priority Research Project "Cell Proliferation Control" International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ras-mediated regional silencing around Fas gene locus2010
- Author(s)
  Masaki Hosogane, Ryo Funayama, Jafar Sharif, Haruhiko Koseki, Keiko Nakayama
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES, Epigenetics, Chromatin & Transcription
- Place of Presentation
  蘇州、中国
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Geminin negatively regulates thrombopoiesis. MEXT Priority Researc Project "Cell Proliferation Control"2010
- Author(s)
  中山啓子
- Organizer
  International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Geminin negatively regulates thrombopoiesis2010
- Author(s)
  Keiko Nakayama
- Organizer
  MEXT Priority Research Project "Cell Proliferation Control" International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Ras-mediated gene silencingによるFas遺伝子領域のエピジェネティック制御2010
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 第33回分子生物学会年会・第83回日本生化学会大会合同大会2010
- Author(s)
  舟山亮, 細金正樹, 西田有一郎, 中山啓子
- Organizer
  がん遺伝子RASによる広範囲染色体領域の遺伝子サイレンシング機構の解析
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] がん遺伝子RASによる広範囲染色体領域の遺伝子サイレンシング機構の解析2010
- Author(s)
  舟山亮, 細金正樹, 西田有一郎, 中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 第33回分子生物学会年会・第83回日本生化学会大会合同大会2010
- Author(s)
  中野星児, 佐々木陽丞, 本橋ほずみ, 中山啓子
- Organizer
  Gemininは造血幹細胞の維持と巨核球の分化を制御する
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] がん遺伝子Rasは複数の遺伝子を含む広範囲な染色体領域を抑制する2010
- Author(s)
  細金正樹、舟山亮、中山啓子
- Organizer
  日本分子生物学会第10回春季シンポジウム
- Place of Presentation
  松島
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Geminlnは造血幹細胞の維持と巨核球の分化を制御する2010
- Author(s)
  中野星児、佐々木陽丞、本橋ほづみ、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ras-mediated regional silencing around Fas gene locus. COLD SPRING HARBOR ASIA CONFERENCES, Epigenetics2010
- Author(s)
  Masaki Hosogane, Ryo Funayama, Jafar Sharif, Haruhiko Koseki, Keiko Nakayama
- Organizer
  Chromatin & Transcription
- Place of Presentation
  蘇州、中国
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Gemininは造血幹細胞の維持と巨核球の分化を制御する2010
- Author(s)
  中野星児, 佐々木陽丞, 本橋ほづみ, 中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] がん遺伝子RASによる広範囲染色体領域の遺伝子サイレンシング機構の解析2010
- Author(s)
  舟山亮、細金正樹、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] がん遺伝子RASによる広範囲染色体領域の遺伝子サイレンシング機構の解析2010
- Author(s)
  舟山亮、細金正樹、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Gemininは造血幹細胞の維持と巨核球の分化を制御する2010
- Author(s)
  中野星児、佐々木陽丞、本橋ほづみ、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Gemininは造血幹細胞の維持と巨核球の分化を制御する2010
- Author(s)
  中野星児、佐々木陽丞、本橋ほづみ、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] がん遺伝子Rasは複数の遺伝子を含む広範囲な染色体領域を抑制する2010
- Author(s)
  細金正樹、舟山亮、中山啓子
- Organizer
  日本分子生物学会第10回春季シンポジウム
- Place of Presentation
  松島
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] がん遺伝子Rasは複数の遺伝子を含む広範囲な染色体領域を抑制する2010
- Author(s)
  細金正樹、舟山亮、中山啓子
- Organizer
  日本分子生物学会第10回春季シンボジウム
- Place of Presentation
  松島
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] がん遺伝子RASによる広範囲染色体領域の遺伝子サイレンシング機構の解析2010
- Author(s)
  舟山亮、細金正樹、西田有一郎、中山啓子
- Organizer
  第33回分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] がん遺伝子Rasは複数の遺伝子を含む広範囲な染色体領域を抑制する2010
- Author(s)
  細金正樹, 舟山亮, 中山啓子
- Organizer
  日本分子生物学会第10回春季シンポジウム
- Place of Presentation
  松島
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ras-mediated regional silencing around Fas gene locus2010
- Author(s)
  Masaki Hosogane, Ryo Funayama, Jafar Sharif, Haruhiko Koseki, Keiko Nakayama
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES, Epigenetics, Chromatin & Transcription
- Place of Presentation
  蘇州、中国
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ras-mediated regional silencing around Fas gene locus2010
- Author(s)
  Masaki Hosogane, Ryo Funayama, Jafar Sharif, Haruhiko Koseki, Keiko Nakayama
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES, Epigenetics, Chromatin & Transcription
- Place of Presentation
  蘇州、中国
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-22657052
[Presentation] Cell cycle control during differentiation : regulation by two F-box protein, Fbw72009
- Author(s)
  中山啓子
- Organizer
  CSI Singapore, NUS-Tohoku University GCOE Joint Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] 東北大学Network Medicine創生拠点冬の合宿2009
- Author(s)
  中山啓子
- Organizer
  タンパク質の翻訳後修飾制御機構とその破綻による疾患発症メカニズムの解明
- Place of Presentation
  仙台
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] ユビキチンリガーゼSCFFbxw7はNotchタンパク質分解によりB細胞の分化を制御する2009
- Author(s)
  青山慧, 石川善則, 小野山一郎, 中山敬一, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Ku80のユビキチン化を介したDNA二重鎖切断修復制御2009
- Author(s)
  石田典子, 家村俊一郎, 安井明, 夏目徹, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 新規ユビキチンリガーゼによるヒストンシャペロンNAP1L1の分解を介した細胞増殖制御2009
- Author(s)
  石田典子, 家村俊一郎, 夏目徹, 中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点冬の合宿2009
- Place of Presentation
  仙台
- Year and Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] ユビキチンリガーゼSCF^<Fbxw7>はNotchタンパク質分解によりB細胞の分化を制御する2009
- Author(s)
  青山慧, 石川善則, 小野山一郎,中山敬一, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Differential tissue specificity of ubiquitinligase SCF^<Fbxw7>2009
- Author(s)
  中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] ユビキチンリガーゼSCFFbxw7はNotchタンパク質分解によりB細胞の分化を制御する2009
- Author(s)
  青山慧, 石川善則, 小野山一郎, 中山敬一, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Differential tissue specificity of ubiquitin ligase SCFFbxw72009
- Author(s)
  中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine 創生拠点国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] T-cell differentiation and proliferation in Geminin gene-deleted mouse2009
- Author(s)
  中野星児, 山田秀俊, 村井寛子, 佐竹正延, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] T-cell differentiation and proliferation in Geminin gene-deleted mouse.2009
- Author(s)
  中野星児, 山田秀俊, 村井寛子, 佐竹正延, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] CSI Singapore, NUS-Tohoku University GCOE Joint Symposium2009
- Author(s)
  中山啓子
- Organizer
  Cell cycle control during differentiation : regulation by two F-box protein, Fbw7
- Place of Presentation
  Singapore
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] 東北大学Network Medicine創生拠点冬の合宿2009
- Author(s)
  山田秀俊, 中山啓子
- Organizer
  GemininはMouse Embryonic Stem CellにおけるDNA複製と遺伝子発現を制御している
- Place of Presentation
  仙台
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Cell cycle control during differentiation : regulation by two F-box protein, Fbw72009
- Author(s)
  中山啓子
- Organizer
  CSI Singapore, NUS-Tohoku University GCOE Joint Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Cell cycle control during differentiation : regulation by two F-box protein, Fbw72009
- Author(s)
  中山啓子
- Organizer
  CSI Singapore, NUS-Tohoku University GCOE Joint Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] ユビキチンリガーゼSCFFbxw 7はNotchタンパク質分解によりB細胞の分化を制御する2009
- Author(s)
  青山慧, 石川善則, 小野山一郎, 中山敬一, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] 第6回東北大学バイオサイエンスシンポジウム2009
- Author(s)
  山田秀俊, 中山啓子
- Organizer
  Gemininはmouse Embryonic Stem CellにおけるDNA複製と遺伝子発現を制御する
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Differential specificity of substrate accumulation in ubiquitin ligase SCFFBXW7 deficient cells2009
- Author(s)
  中山啓子
- Organizer
  nstitite of Molecular and Cell Biology(IMCB)Cell Cycle Regulation and Tumorigenesis Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Differential specificity of substrate accumulation in ubiquitin ligase SCFFBXW7 deficient cells2009
- Author(s)
  中山啓子
- Organizer
  nstitite of Molecular and Cell Biology(IMCB)Cell Cycle Regulation and Tumorigenesis Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Differential tissue specificity of ubiquitin ligase SCFFbxw72009
- Author(s)
  中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Differential specificity of substrate accumulation in ubiquitinligase SCFFBXW7 deficient cells.2009
- Author(s)
  中山啓子
- Organizer
  Institite of Molecular and Cell Biology (IMCB) Cell Cycle Regulation and Tumorigenesis Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Defect of T-cell differentiation and proliferation in Geminin gene deleted mouse.2009
- Author(s)
  中野星児, 中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Cell cycle control during differentiation : regulation by two F-box protein, Fbw7. CSI Singapore2009
- Author(s)
  中山啓子
- Organizer
  NUS- Tohoku University GCOE Joint Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ku80のユビキチン化を介したDNA二重鎖切断修復制御2009
- Author(s)
  石田典子, 家村俊一郎, 安井明, 夏目徹, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Differential specificity of substrate accumulation in ubiquitin ligase SCFFBXW7 deficient cells2009
- Author(s)
  中山啓子
- Organizer
  nstitite of Molecular and Cell Biology(IMCB)Cell Cycle Regulation and Tumorigenesis Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] 核内IKKβを介したNF-kB活性化による細胞死亢進2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ku80のユビキチン化を介したDNA二重鎖切断修復制御2009
- Author(s)
  石田典子, 家村俊一郎, 安井明, 夏目徹, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] 核内IKKβを介したNF-kB活性化による細胞死充進2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PLANNED-19057001
[Presentation] Gemininはmouse Embryonic Stem CellにおけるDNA複製と遺伝子発現を制御する2009
- Author(s)
  山田秀俊, 中山啓子
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] T-cell differentiation and proliferation in Geminin gene-deleted mouse2009
- Author(s)
  中野星児, 山田秀俊, 村井寛子, 佐竹正延, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] Differential tissue specificity of ubiquitin lipase SCFFbxw72009
- Author(s)
  中山啓子
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] T-cell differentiation and proliferation in Geminin gene-deleted mouse2009
- Author(s)
  中野星児, 山田秀俊, 村井寛子, 佐竹正延, 中山啓子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 核内IKKβを介したNF-kB活性化による細胞死亢進2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20370076
[Presentation] ユビキチンリガーゼSCF^<Fbxw7>は表皮角化細胞において増殖と分化を抑制する2008
- Author(s)
  石川善則, 小野山一郎, 中山敬一, 中山啓子
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] 新規RING-Fingerタンパク質はNAP1L1のユビキチン化を介して細胞増殖を抑制する2008
- Author(s)
  石田典子, 家村俊一郎, 夏目徹, 中山啓子
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] ノックインマウスを用いたp27とp57の機能的類似性と特異性の検討2008
- Author(s)
  州崎悦生, 中山啓子, 中山敬一
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Gdx, an X-Linked Ubiquitin-Like Modifier, Is Conjugated to Cyclin F and Regulates Mitosis2008
- Author(s)
  Ishida, N., Hatakeyama, S., Nakayama, K. and Nakayama, K.-I.
- Organizer
  4th International Conference, Ubiquitin, Ubiquitin-Like Proteins, and Cancer
- Place of Presentation
  Huston, TX, USA
- Year and Date
  2008-02-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] ユビキチンリガーゼSCF^Fbxw7>はBリンパ球の分化・生存の抑制因子である2008
- Author(s)
  青山慧, 石川善則, 小野山一郎, 中山敬一, 中山啓子
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20570175
[Presentation] Ubiquitin ligases required for the regulation of G0-G1 transision.2007
- Author(s)
  Nakayama, K., et. al.
- Organizer
  Office of Life Sciences/National University of Singapore and Tohoku University/Center of Excellence Joint Syposium
- Place of Presentation
  Singapore
- Year and Date
  2007-09-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Ubiquitin ligases required for the regulation of G0-G1 transision.2007
- Author(s)
  Nakayama, K., et. al.
- Organizer
  Office of Life Sciences/National University of Singapore and Tohoku University/Center of Excellence Joint Syposium
- Place of Presentation
  Singapore
- Year and Date
  2007-05-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] Ubiquitin ligases required for the regulation of G0-G1 transision2007
- Author(s)
  Nakayama, K.
- Organizer
  Office of Life Sciences/National University of Singapore and Tohoku University/Center of Excellence Joint
- Place of Presentation
  Syposium, Singapore
- Year and Date
  2007-09-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Geminin is essential for development of preimplantation embryos2006
- Author(s)
  Hara, K., Nakayama, K. and Nakayama, K.
- Organizer
  Cold Spring Harbor Symposium"The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] RASSF1A is required for Skp2-mediated G1-S transition and stabilization of p532006
- Author(s)
  Song, M.S., Song, S.J., Kim, S.Y., Yang, T.-H., Pfeifer, G.P., Nakayama, K., Nakayama, K.I. and Lim, D.-S.
- Organizer
  Cold Spring Harbor Symposium"The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] Control of Cell Cycle and Chromosomal Stability2006
- Author(s)
  Nakayama, K. and Igarashi, K.
- Organizer
  The 3rd Intermational Symposium on "Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] RASSF1A is required for Skp2-mediated G1-S transition and stabilization of p532006
- Author(s)
  Song, M.S., Song, S.J., Kim, S.Y., Yang, T.-H., Pfeifer, G.P., Nakayama, K., Nakayama, K.I. and Lim, D.-S.
- Organizer
  Cold Spring Harbor Symposium "The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Regulation of CDK inhibitors by ubiquitin ligase Fbxw72006
- Author(s)
  S Ishikawa, Y., Onoyama, I., Nakayama, K.-i. and Nakayama, K.
- Organizer
  20th IUBMB Internatinal Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] FBW7 is a key regulator of Cell Cycle arrest and Tumorigenesis2006
- Author(s)
  Nakayama, K.
- Organizer
  The 3rd International Symposium on "Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Control of Cell Cycle and Chromosomal Stability.2006
- Author(s)
  Nakayama, K., et. al.
- Organizer
  The 3rd International Symposium on "Novel perspecfives in cancer research and translationto the clinic
- Place of Presentation
  Sendai,Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] FBW7 is a key regulator of Cell Cycle arrest and Tumorigenesis.2006
- Author(s)
  Nakayama, K.
- Organizer
  The 3rd International Symposium on "Novel perspectives in cancer research and translation to the clinic,
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] GdX, An X-Linked ubiquitin-like modifier, is conjugated to cyclin F and regulates mitotic exit2006
- Author(s)
  Ishida, N., Hatakeyama, S., lemura, S., Natsume, T., Nakayama, K. and Nakayama, K.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Accumulation of Notch induces cell cycle arrest in the tumor suppressor Fbxw7-deficient MEFs2006
- Author(s)
  Ishikawa, Y., Onoyama, I., Nakayama, K.-i. and Nakayama, K.
- Organizer
  The 3rd International Symposium on "Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] p27 can substitute for p57 in mouse development2006
- Author(s)
  Susaki, E., Nakayama, K. and Nakayama, K.I.
- Organizer
  Cold Spring Harbor Symposium "The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Geminin is essential for the development of preimplantation mouse embryos2006
- Author(s)
  Hara, K., Nakayama, K. and Nakayam, K.
- Organizer
  The 3rd International Symposium on "Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] FBW7 is a key regulator of Cell Cycle arrest and Tumorigenesis.2006
- Author(s)
  Nakayama, K.
- Organizer
  The 3rd International Symposium on"Novel perspectives in cancer research and translation to the clinic,
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Control of Cell Cycle and Chromosomal Stability.2006
- Author(s)
  Nakayama, K., et. al.
- Organizer
  The 3rd International Symposium on ゛Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] The role of FWD1a and FWD1b as circadian rhythm formation2006
- Author(s)
  Ohsaki, K., Oishi, K., Kozono, Y., Nakayama, K., Nakayama, K.I. and Ishida, N.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Suppression of centrosome amplification after DNA damage depends on p27 accumulation2006
- Author(s)
  Sugihara, E., Nakayama, K., Nakayama, K.I., Saya, H. and Miwa, M.
- Organizer
  20trh IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] GdX, an X-linked ubiquitin-like modifier, is conjugated to cyclin F and regulates cell cycle2006
- Author(s)
  Ishida, N., Hatakeyama, S., Nakayama, K. and Nakayama, K.
- Organizer
  The 3rd International Symposium on "Novel perspectives in cancer research and translation to the clinic
- Place of Presentation
  Sendai, Japan
- Year and Date
  2006-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
[Presentation] Fbw7 is a key regulator of cell-cycle arrest and tumorigenesis during development2006
- Author(s)
  Onoyama, I., Tsunematsu, R., Nakayama, K. and Nakayama, K.I.
- Organizer
  Cold Spring Harbor Symposium"The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370075
[Presentation] Fbw7 contributes to cell-cycle regulation and tumor suppression during development2006
- Author(s)
  Onoyama, I., Tsunematsu, R., Nakayama, K. and Nakayama, K.I.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570171
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# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakayama Keiko 中山 啓子

NAKAYAMA Keiko 中山 啓子

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Regulation of tumor progression by selective splicing of Fibulin 2 in the tumor environmentPrincipal Investigator

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Function of SETD5 in pancreatic cancerPrincipal Investigator

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Elucidation of the signaling pathways that induce gene amplificationPrincipal Investigator

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細胞老化へ向かう代謝アダプテーションのエピゲノムからの探索Principal Investigator

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Elucidation of the mechanism of transcription elongation rate control by histone codePrincipal Investigator

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Verification of genomic diversity required for tumorigenesisPrincipal Investigator

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Verification of genomic diversity required for tumorigenesisPrincipal Investigator

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Elucidation of transcriptional regulation by histone modification patternPrincipal Investigator

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Comprehensive screening of histone modifying enzymePrincipal Investigator

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Nakayama Keiko 中山啓子

NAKAYAMA Keiko 中山啓子