Kawamata Jun 川又純

… Alternative Names

KAWAMATA Jun 川又純

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Researcher Number	60360814
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017: 札幌医科大学, 医学部, 准教授 2015 – 2016: 札幌医科大学, 医学部, 講師 2010: 札幌医科大学, 医学部, 講師 2007 – 2009: 京都大学, 医学研究科, 助教 2005 – 2006: 京都大学, 医学研究科, 助手 2004: 京都大学, 医学研究科(科学技術振興)(常勤形態), 研究員 2003: 京都大学, 医学研究科, 研究員(科学技術振興常勤形態)
Review Section/Research Field	Principal Investigator Psychiatric science / Neurology Except Principal Investigator Neurology / Biological Sciences
Keywords	Principal Investigator SOD1 / HSP / ALS / アルツハイマー / CRISPR/Cas9 / トランスジェニックマウス / プレセニリン１ / BPSD / アルツハイマー病 / Neuroprotection / 神経保護 … More Except Principal Investigator … More 運動ニューロン / 筋萎縮性側索硬化症 / パーキンソン病 / 治療 / Cre-lox system / タンパク分解 / アルツハイマー病 / VAChT-Cre / コンディショナルノックアウトマウス / 26Sプロテアソーム / RP t 3 / モデル動物 / 神経変性疾患 / コンディショナルノックアウト / Rpt3 / プロテアソーム / ALS / NET / ノルアドレナリン / Pael-R / ユビキチンリガーゼ / PARK 2 / AR-JP / アデノウイルス / MEF / 遺伝子ノックアウトマウス / ATF6α / 小胞体ストレス / Parkin / パーンソン病 / 聴覚誘発磁場 / LGI1遺伝子 / てんかん / 臨床 / 遺伝子 / 生理学 / 脳神経疾患 / phenotype / genotype / LGI1 遺伝子 / 部分てんかん / 常染色体優性外側側頭葉てんかん / 変異SOD1 / SOD1 / 誘導剤 / HSP / 分子シャペロン / 細胞死 / α7受容体 / 神経保護 / アセチルコリンエステラーゼインヒビター / SOD1トランスジェニックマウス / ニコチン性受容体 / ニコチン Less

Establishment of AD model mice harboring novel pathogenic PS1 mutation presenting "Behavioral and Psychological Symptoms of Dementia"Principal Investigator
- Principal Investigator
  
  Kawamata Jun
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
パエル受容体のドーパミンニューロンの機能維持と変性における役割の解明
- Principal Investigator
  
  TAKAHASHI Ryosuke
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
The analysis of participation in the ubiquitin proteasome system for understanding the mechanisms of neurodegenerative diseases.
- Principal Investigator
  
  TAKAHASHI Ryosuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
A multidisciplinary study of autosomal dominant lateral temporal lobe epilepsy (ADLTE)
- Principal Investigator
  
  IKEDA Akio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
筋萎縮性側索硬化症治療薬としての分子シャペロン誘導剤の探索研究
- Principal Investigator
  
  下濱俊
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Sapporo Medical University
  Kyoto University
Mechanism of neuroprotection by the heat shock proteins in amyotrophic lateral sclerosis model mice (SOD1-G93S transgenic mice)Principal Investigator
- Principal Investigator
  
  KAWAMATA Jun
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
ニコチン性受容体作動薬は筋萎縮性側索硬化症に対する新たな治療薬となりうるか?
- Principal Investigator
  
  SHIMOHARA Shun
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyoto University

All 2017 2015 2010 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 脳神経科学イラストレイテッド(改訂第2版)2006
- Author(s)
  川又純, 高橋良輔(分担執筆)
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590872
[Journal Article] Effect of local cooling on excitation-contraction coupling in myasthenic muscle: Another mechanism of ice-pack test in myasthenia gravis.2017
- Author(s)
  Yamamoto D, Imai T, Tsuda E, Hozuki T, Yamauchi R, Hisahara S, Kawamata J, Shimohama S.
- Journal Title
  
  Clin Neurophysiol.
  
  Volume: 128 Issue: 11 Pages: 2309-2317
- DOI
  10.1016/j.clinph.2017.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09840
[Journal Article] Role of Suppressor of Cytokine Signaling 3 (SOCS3) in Altering Activated Microglia Phenotype in APPswe/PS1dE9 Mice.2017
- Author(s)
  Iwahara N, Hisahara S, Kawamata J, Matsumura A, Yokokawa K, Saito T, Fujikura M, Manabe T, Suzuki H, Matsushita T, Suzuki S, Shimohama S.
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 55 Issue: 3 Pages: 1235-1247
- DOI
  10.3233/jad-160887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09840, KAKENHI-PROJECT-16H05279
[Journal Article] Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study.2017
- Author(s)
  Howard JF Jr, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Muppidi S, Nowak RJ, O'Brien F, Wang JJ, Mantegazza R; REGAIN Study Group.(collaborators: Kawamata J.他）
- Journal Title
  
  Lancet Neurol.
  
  Volume: 16 Issue: 12 Pages: 976-986
- DOI
  10.1016/s1474-4422(17)30369-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09840
[Journal Article] Temporal Changes of CD68 and α7 Nicotinic Acetylcholine Receptor Expression in Microglia in Alzheimer’s Disease-Like Mouse Models2015
- Author(s)
  Akihiro Matsumura, Syuuichirou Suzuki, Naotoshi Iwahara, Shin Hisahara, Jun Kawamata, Hiromi Suzuki, Ayano Yamauchi, Kazuyuki Takata, Yoshihisa Kitamura and Shun Shimohama
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 44 Issue: 2 Pages: 409-423
- DOI
  10.3233/jad-141572
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659352, KAKENHI-PROJECT-15K09840, KAKENHI-PROJECT-25460109
[Journal Article] Evaluation of oxidative stress in the brain of a transgenic mouse model of Alzheimer disease by in vivo electron paramagnetic resonance imaging.2015
- Author(s)
  Matsumura A, Emoto MC, Suzuki S, Iwahara N, Hisahara S, Kawamata J, Suzuki H,Yamauchi A, Sato-Akaba H, Fujii HG, Shimohama S.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 85 Pages: 165-173
- DOI
  10.1016/j.freeradbiomed.2015.04.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09840, KAKENHI-PROJECT-15K19288, KAKENHI-PROJECT-26861008
[Journal Article] PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity.2010
- Author(s)
  Aoyagi N, Uemura K, Kuzuya A, Kihara T, Kawamata J, Shimohama S, Kinoshita A, Takahashi R
- Journal Title
  
  Biochem. Biophys. Res.Commun. 391
  
  Pages: 1240-1245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn from patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis.2010
- Author(s)
  Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Ihara M, Kawamata J, Akiguchi I, Fujimura H, Sakoda S, Kusaka H, Hirano A, Takahashi R
- Journal Title
  
  Neuropath. Appl.Neurobiol. 36
  
  Pages: 331-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] Leukoencephalopathy with cognitive impairment following tocilizumab for the treatment of rheumatoid arthritis (RA).2009
- Author(s)
  Kobayashi K, Okamoto Y, Inoue H, Usui T, Ihara M, Kawamata J, Miki Y, Mimori T, Tomimoto H, Takahashi R
- Journal Title
  
  Intern Med. 48
  
  Pages: 1307-1309
- NAID
  130000121960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy : the first report from Asian families2009
- Author(s)
  Kawamata J, Ikeda A, Fujita Y, Usui K, Shimohama S, Takahashi R
- Journal Title
  
  Epilepsia (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy : The first report from Asian families.2009
- Author(s)
  Kawamata J, Ikeda A, Fujita Y, Usui K, Shimohama S, Takahashi R
- Journal Title
  
  Epilepsia. Sep22.[Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy : The first report from Asian families.2009
- Author(s)
  Kawamata J
- Journal Title
  
  Epilepsia
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023015
[Journal Article] Leucine-rich glioma-inactivated 1 (LGI1)変異を伴う常染色体優性外側側頭葉てんかんの1例2009
- Author(s)
  藤田祐之, 池田昭夫, 門野賢太郎, 川又純, 冨本秀和, 福山秀直, 高橋良輔
- Journal Title
  
  臨床神経学 49
  
  Pages: 186-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] Abnormal auditory cortex with giant N100m signal in patients with autosomal dominant lateral temporal lobe epilepsy.2009
- Author(s)
  Usui K, Ikeda A, Nagamine T, Matsubayashi J, Matsumoto R, Hiraumi H, Kawamata J, Matsuhashi M, Takahashi R, Fukuyama H.
- Journal Title
  
  Clin Neurophysiol. 120
  
  Pages: 1923-1926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy : The first report from Asian families2009
- Author(s)
  Kawamata J
- Journal Title
  
  Epilepsia
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390244
[Journal Article] Leucine-rich glioma-inactivated 1(LGI1)変異を伴う常染色体優性外側側頭葉てんかんの1 例2009
- Author(s)
  藤田祐之、池田昭夫、門野賢太郎、川又純、冨本秀和、福山秀直、高橋良輔
- Journal Title
  
  臨床神経学 (印刷中)
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] 稀発大発作と振戦様ミオクローヌスを認めたUnverricht-Lundborg 病の成人例2009
- Author(s)
  近藤孝之、山中崇弘、山門穂高、川又純、冨本秀和、人見健文、池田昭夫、高橋良輔
- Journal Title
  
  臨床神経 49
  
  Pages: 43-47
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy : the first report from Asian families2009
- Author(s)
  Kawamata J, Ikeda A, Fujita Y, Usui K, Shimohama S, Takahas hi R
- Journal Title
  
  Epilepsia (in press)
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] 稀発大発作と振戦様ミオクローヌスを認めたUnverricht-Lundborg病の成人例2008
- Author(s)
  近藤孝之, 山中崇弘, 山門穂高, 川又純, 冨本秀和, 人見健文, 池田昭夫, 高橋良輔
- Journal Title
  
  臨床神経 49
  
  Pages: 43-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] 稀発大発作と振戦様ミオクローヌスを認めたUnverricht-Lundborg病の成人例2008
- Author(s)
  近藤孝之, 山中崇弘, 山門穂高, 川又純, 冨本秀和, 人見健文, 池田昭夫, 高橋良輔
- Journal Title
  
  臨床神経学 (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590935
[Journal Article] Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase : clues to a possible strategy for treating ALS.2007
- Author(s)
  Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S
- Journal Title
  
  Journal of Neurochemistry Mar 30 [Epub ahead of print]
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590872
[Journal Article] Heat-snock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase : clues to a possible strategy for treating ALS2007
- Author(s)
  Yamashita H, Kawamata J, Ukawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S
- Journal Title
  
  Journal of Neurochemistry Mar 30[Epub ahead of print]
- Data Source
  KAKENHI-PROJECT-17590872
[Journal Article] Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase : clues to a possible strategy for treating ALS.2007
- Author(s)
  Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S.
- Journal Title
  
  J Neurochem. (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590872
[Presentation] Decision making of using invasive mechanical ventilation in patients with amyotrophic lateral sclerosis in Sapporo area2017
- Author(s)
  J. Kawamata, D. Yamamoto, T. Matsushita, A. Matsumura, S. Suzuki, S. Hisahara, S. Shimohama, E. Tsuda, R. Yamauchi
- Organizer
  XXIII World Congress of Neurology WCN2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09840

1. SHIMOHARA Shun (60235687)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. KINOSHITA Masako (90402883)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAGAMINE Takashi (10231490)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. USUI Keiko (60402872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. TAKAHASHI Ryosuke (90216771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. MISAWA Hidemi (80219617)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. INOUE Haruhisa (70332327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. IKEDA Akio (90212761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. ISHIZU Kouichi (50314224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATSUMOTO Riki (00378754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森脇康博 (00392150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松村晃寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawamata Jun 川又 純

KAWAMATA Jun 川又 純

Research Projects

Research Products

Co-Researchers

Establishment of AD model mice harboring novel pathogenic PS1 mutation presenting "Behavioral and Psychological Symptoms of Dementia"Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

パエル受容体のドーパミンニューロンの機能維持と変性における役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The analysis of participation in the ubiquitin proteasome system for understanding the mechanisms of neurodegenerative diseases.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A multidisciplinary study of autosomal dominant lateral temporal lobe epilepsy (ADLTE)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

筋萎縮性側索硬化症治療薬としての分子シャペロン誘導剤の探索研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of neuroprotection by the heat shock proteins in amyotrophic lateral sclerosis model mice (SOD1-G93S transgenic mice)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ニコチン性受容体作動薬は筋萎縮性側索硬化症に対する新たな治療薬となりうるか?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 脳神経科学イラストレイテッド(改訂第2版)2006

Author(s)

Publisher

Description

Data Source

[Journal Article] Effect of local cooling on excitation-contraction coupling in myasthenic muscle: Another mechanism of ice-pack test in myasthenia gravis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Suppressor of Cytokine Signaling 3 (SOCS3) in Altering Activated Microglia Phenotype in APPswe/PS1dE9 Mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Temporal Changes of CD68 and α7 Nicotinic Acetylcholine Receptor Expression in Microglia in Alzheimer’s Disease-Like Mouse Models2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of oxidative stress in the brain of a transgenic mouse model of Alzheimer disease by in vivo electron paramagnetic resonance imaging.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity.2010

Author(s)

Journal Title

Kawamata Jun 川又純

KAWAMATA Jun 川又純