Toyohara Takafumi 豊原敬文

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TOYOHARA Takafumi 豊原敬文

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Researcher Number	60594182
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北大学, 大学病院, 准教授 2021 – 2023: 東北大学, 医工学研究科, 特任講師 2019 – 2020: 東北大学, 医工学研究科, 特任助教 2012 – 2014: 京都大学, iPS細胞研究所, 研究員 2012: 京都大学, iPS細胞研究所, 特定研究員 2011: 京都大学, ｉＰＳ細胞研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine / 0902:General internal medicine and related fields Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 55020:Digestive surgery-related / Basic Section 53040:Nephrology-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator iPS細胞 / 国際情報交換　アメリカ合衆国 / 腎前駆細胞 / 慢性腎臓病 / 腎硬化症 / 糖尿病性腎症 / AADAC / 脂質代謝 / 糖尿病性腎臓病 / 糖尿病 … More / 多能性幹細胞 / ES細胞 / 糸球体 / 腎臓 / 内皮細胞 / 急性腎障害 / 急性腎不全 / ネフロン前駆細胞 / 再生医学 / 国際情報交流　アメリカ合衆国 / SIX2 … More Except Principal Investigator iPS細胞 / ミトコンドリア病 / RNF213 / 血管平滑筋 / 血管内皮 / もやもや病 / 人工腸 / 回腸嚢炎 / 腸内細菌叢 / 抗菌ペプチド / 人工腸管 / 潰瘍性大腸炎 / オルガノイド / ミトフィリン / 心筋細胞 / ミドコンドリア病 / 人工心筋 / 人工血管 / ミトコンドリア / tRNAs / LC-MS/MS / 修飾核酸 / MELAS / tRNA Less

Elucidating the pathological mechanism and developing the clinical markers for nephrosclerosis by iPS cellsPrincipal Investigator
- Principal Investigator
  
  豊原敬文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
Elucidation of the pathogenesis of moyamoya disease through Endothelial-Smooth Muscle Interaction and RNF213
- Principal Investigator
  
  新妻邦泰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Elucidation of the pathogenesis of ulcerative colitis using an early-onset model of human artificial intestine
- Principal Investigator
  
  神山篤史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Profiling of modified nucleosides in mitochondrial tRNAs for diagnosis of mitochondrial diseases
- Principal Investigator
  
  Akiyama Yasutoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku University
Development of novel therapy for diabetic nephropathy using lipid metabolismPrincipal Investigator
- Principal Investigator
  
  Toyohara Takafumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
Development of mitochondria homing drug for kidney disease
- Principal Investigator
  
  Suzuki Takehiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
Developing the differentiation methods from pluripotent stem cells to glomerular endothelial cells for diabetic researchPrincipal Investigator
- Principal Investigator
  
  Toyohara Takafumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Tohoku University
Development of cell therapy using hiPS-derived nephron progenitorsPrincipal Investigator
- Principal Investigator
  
  TOYOHARA Takafumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University
Development of differentiation methods from human pluripotent stemcells into renal progenitor cellsPrincipal Investigator
- Principal Investigator
  
  TOYOHARA Takafumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2015 2014 2013 Other

All Journal Article Presentation Book Other

[Book] 再生医療における臨床研究と製品開発2013
- Author(s)
  豊原敬文　長船健二
- Total Pages
  6
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-25860674
[Journal Article] Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease2023
- Author(s)
  Oshita Toma、Watanabe Shun、Toyohara Takafumi、Kujirai Ryota、Kikuchi Koichi、Suzuki Takehiro、Suzuki Chitose、Matsumoto Yotaro、Wada Jun、Tomioka Yoshihisa、Tanaka Tetsuhiro、Abe Takaaki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 12508-12508
- DOI
  10.1038/s41598-023-39657-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06737, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-21K08270
[Journal Article] “Coexistence of IgA nephropathy and renal artery stenosis in Takayasu arteritis: case report and literature review”2022
- Author(s)
  Ito Nono、Shirai Tsuyoshi、Toyohara Takafumi、Hashimoto Hideaki、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology International
  
  Volume: Ahead of print Issue: 2 Pages: 391-398
- DOI
  10.1007/s00296-021-05066-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08245, KAKENHI-PROJECT-21K08469
[Journal Article] L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism2021
- Author(s)
  Sato Miku、Harada-Shoji Narumi、Toyohara Takafumi、Soga Tomoyoshi、Itoh Masatoshi、Miyashita Minoru、Tada Hiroshi、Amari Masakazu、Anzai Naohiko、Furumoto Shozo、Abe Takaaki、Suzuki Takashi、Ishida Takanori、Sasano Hironobu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 589-589
- DOI
  10.1038/s41598-020-80668-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08948, KAKENHI-PROJECT-19K23933, KAKENHI-PROJECT-19K09065
[Journal Article] Fibromuscular dysplasia with recurrence after "long-term" following percutaneous transcatheter renal angioplasty: two case reports with a review of 26 patients2021
- Author(s)
  Oribe S, Toyohara T, Mishima E, Suzuki T, Kikuchi K, Watanabe S, Morita Y, Ota H, Seiji K, Miyazaki M, Takase K, Abe T
- Journal Title
  
  BMC Nephrol
  
  Volume: 22 Issue: 1 Pages: 187-187
- DOI
  10.1186/s12882-021-02342-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03613, KAKENHI-PROJECT-21K08245, KAKENHI-PROJECT-21K16178
[Journal Article] CE-MS-Based Identification of Uremic Solutes Specific to Hemodialysis Patients2021
- Author(s)
  Akiyama Yasutoshi、Kikuchi Koichi、Toyohara Takafumi、Mishima Eikan、Suzuki Chitose、Suzuki Takehiro、Nakayama Masaaki、Tomioka Yoshihisa、Soga Tomoyoshi、Abe Takaaki
- Journal Title
  
  Toxins
  
  Volume: 13 Issue: 5 Pages: 324-324
- DOI
  10.3390/toxins13050324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08245, KAKENHI-PROJECT-21K08270, KAKENHI-PROJECT-21K16178
[Journal Article] Treatment of Refractory Hypertension with Timely Angioplasty in Total Renal Artery Occlusion with Atrophic Kidney2021
- Author(s)
  Sasaki Yuri、Mishima Eikan、Kikuchi Koichi、Toyohara Takafumi、Suzuki Takehiro、Ota Hideki、Seiji Kazumasa、Miyazaki Mariko、Harigae Hideo、Ito Sadayoshi、Takase Kei、Abe Takaaki
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 2 Pages: 287-292
- DOI
  10.2169/internalmedicine.5290-20
- NAID
  130007968948
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-01-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K23933
[Journal Article] HPRT-related hyperuricemia with a novel p.V35M mutation in HPRT1 presenting familial juvenile gout.2020
- Author(s)
  Mishima E, Mori T, Nakajima Y, Toyohara T, Kikuchi K, Oikawa Y, Matsuhashi T, Maeda Y, Suzuki T, Kudo M, Ito S, Sohara E, Uchida S, Abe T.
- Journal Title
  
  CEN Case Rep
  
  Volume: pub Issue: 3 Pages: 210-214
- DOI
  10.1007/s13730-020-00459-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17733, KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K23933
[Journal Article] Concurrent analogous organ damage in the brain, eyes, and kidneys in malignant hypertension: reversible encephalopathy, serous retinal detachment, and proteinuria2020
- Author(s)
  Mishima E, Funayama Y, Suzuki T, Mishima F, Nitta F, Toyohara T, Kikuchi K, Kunikata H, Hashimoto J, Miyazaki M, Harigae H, Nakazawa T, Ito S, Abe T.
- Journal Title
  
  Hypertension Research
  
  Volume: 44 Issue: 1 Pages: 88-97
- DOI
  10.1038/s41440-020-0521-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11504, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K23933
[Journal Article] Kidney enlargement effect of angioplasty for nonatherosclerotic renovascular disease: reversibility of ischemic kidney2020
- Author(s)
  Iwasaki Tomoyuki、Mishima Eikan、Suzuki Takehiro、Kikuchi Koichi、Toyohara Takafumi、Seiji Kazumasa、Takase Kei、Miyazaki Mariko、Harigae Hideo、Ito Sadayoshi、Abe Takaaki
- Journal Title
  
  Hypertension Research
  
  Volume: 43 Issue: 11 Pages: 1214-1221
- DOI
  10.1038/s41440-020-0473-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K23933, KAKENHI-PROJECT-19K23994, KAKENHI-PROJECT-20H03613
[Journal Article] Germ-free conditions modulate host purine metabolism, exacerbating adenine-induced kidney damage.2020
- Author(s)
  Mishima E, Ishijo M, Kawabe T, Kikuchi K, Akiyama Y, Toyohara T, Suzuki C, Asao A, Ishii N, Fukuda S, Abe T
- Journal Title
  
  Toxins
  
  Volume: 12 Issue: 9 Pages: 547-547
- DOI
  10.3390/toxins12090547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08766, KAKENHI-PROJECT-20K16272, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08199, KAKENHI-PROJECT-19K23933, KAKENHI-PROJECT-19K23994
[Journal Article] Apparent Diffusion Coefficient in the Resolution of Renal Ischemia after Angioplasty on Diffusion-weighted Imaging: Renal Artery Stenosis Caused by Progressive Thrombosis in Residual Chronic Aortic Dissection2020
- Author(s)
  Mishima Eikan、Ota Hideki、Suzuki Takehiro、Toyohara Takafumi、Seiji Kazumasa、Ito Sadayoshi、Saiki Yoshikatsu、Takase Kei、Abe Takaaki
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 9 Pages: 1173-1177
- DOI
  10.2169/internalmedicine.3855-19
- NAID
  130007839437
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-19K23933
[Journal Article] Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.2020
- Author(s)
  Friesen M, Warren CR, Yu H, Toyohara T, Ding Q, Florido MHC, Sayre C, Pope BD, Goff LA, Rinn JL, Cowan CA.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 14 Issue: 4 Pages: 590-602
- DOI
  10.1016/j.stemcr.2020.03.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23933
[Journal Article] Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-52020
- Author(s)
  Oikawa Yoshitsugu、Izumi Rumiko、Koide Masashi、、、Aoki Masashi、Kure Shigeo、Abe Takaaki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 12 Pages: e0231064-e0231064
- DOI
  10.1371/journal.pone.0231064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-19H03701, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08199, KAKENHI-PROJECT-19K17921, KAKENHI-PROJECT-19K23933, KAKENHI-PROJECT-20H04118
[Journal Article] A nonhuman primate model of liver fibrosis towards cell therapy for liver cirrhosis.2020
- Author(s)
  Yasuda K, Kotaka M, Toyohara T, Sueta SI, Katakai Y, Ageyama N, Uemoto S, Osafune K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 20 Issue: 3 Pages: 30643-30644
- DOI
  10.1016/j.bbrc.2020.03.148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23933
[Journal Article] Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis2020
- Author(s)
  Toyohara Takafumi、Roudnicky Filip、Florido Mary H.C.、Nakano Toshiaki、Yu Haojie、Katsuki Shunsuke、Lee Minjin、Meissner Torsten、Friesen Max、Davidow Lance S.、Ptaszek Leon、Abe Takaaki、Rubin Lee L.、Pereira Alexandre C.、Aikawa Masanori、Cowan Chad A.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 27 Issue: 1 Pages: 147-157.e7
- DOI
  10.1016/j.stem.2020.04.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23933
[Journal Article] GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis2019
- Author(s)
  Yu H、Rimbert A、Palmer AE.、Toyohara T、Xia Y、Xia F、Ferreira LMR.、Chen Z、Chen T、Loaiza N、Horwitz NB、Kacergis Michael C、Zhao L、Soukas AA.、Kuivenhoven JA、Kathiresan S、Cowan CA.
- Journal Title
  
  Cell
  
  Volume: 179 Issue: 6 Pages: 1276-1288.e14
- DOI
  10.1016/j.cell.2019.10.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23933
[Journal Article] iPS細胞を用いた腎疾患治療2013
- Author(s)
  豊原敬文　長船健二
- Journal Title
  
  腎と透析
  
  Volume: 75 Pages: 850-855
- Data Source
  KAKENHI-PROJECT-25860674
[Presentation] 透析導入期における血中腸内細菌由来毒素の解析2023
- Author(s)
  豊原敬文、山本多恵、金光祥臣、菊地　晃一、渡邉　駿、鈴木　健弘、田中　哲洋、阿部　高明
- Organizer
  第68回日本透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] Elobixibat 投与マウスにおける胆汁酸および腸内細菌叢の検討2023
- Author(s)
  蓑輪　圭太，秋山　由雅子，笠原　朋子，何　欣蓉，前川　正充，菊池　晃一，豊原　敬文，鈴木　健弘，鈴木　千登世，鯨井　涼太，松本　洋太郎，富岡　佳久，阿部　高明
- Organizer
  第66回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 新規ミトコンドリア病治療薬MA-5による難聴治療2023
- Author(s)
  鈴木健弘、豊原敬文、鈴木千登世、本蔵洋平、藤岡正人、香取幸夫、阿部高明
- Organizer
  ムーンショット目標２×７技術交流会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 尿毒素フェニル硫酸はインスリン分泌を刺激し糖尿病性腎症におけるインスリン抵抗性を惹起する2023
- Author(s)
  頓宮　慶泰，笠原　朋子，川邊　千陽，鈴木　健新，菊地　晃一，三瀬　広記，鯨井　涼太，松本　洋太郎，秋山　泰利，渡邉　駿，豊原　敬文，鈴木　健弘，和田　淳，富岡　佳久，田中　哲洋，阿部　高明
- Organizer
  第66回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 腎不全患者の尿毒症物質生成に関与する腸内細菌の解析2023
- Author(s)
  豊原　敬文，杉峯　諒，渡邉　駿，菊地　晃一，鈴木　健弘，鯨井　涼太，富岡　佳久，田中　哲洋，阿部　高明
- Organizer
  第66回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 腎血管性高血圧における腎動脈狭窄の流体力学要因の検討2023
- Author(s)
  是方真悠子、板井駿、豊原敬文、渡邉駿、菊池晃一、鈴木健弘、阿部高明、田中哲洋
- Organizer
  第45回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 糖尿病性腎臓病の腎予後予測マーカーとしてのフェニル硫酸の有用性2023
- Author(s)
  菊地　晃一，鯨井　涼太，松本　洋太郎，中村　智洋，渡邉　駿，三瀬　広記，豊原　敬文，鈴木　健弘，富岡　佳久，和田　淳，阿部　高明
- Organizer
  第66回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 動脈硬化における小胞体リパーゼとミトコンドリアの働きについて2022
- Author(s)
  豊原敬文
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 腎不全患者の尿毒症物質生成に関与する腸内細菌の解析2022
- Author(s)
  杉峯諒、豊原敬文、渡邉駿、菊地晃一、鈴木健弘、鯨井涼太、富岡佳久、田中哲洋、阿部高明
- Organizer
  第44 回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 尿毒素フェニル硫酸は糖尿病性腎症におけるインスリン分泌促進とインスリン抵抗性に関与する2022
- Author(s)
  頓宮慶泰、菊地晃一、鈴木健新、三瀬広記、和田淳、秋山泰利、那谷耕司、鯨井涼太、松本洋太郎、富岡佳久、渡邉駿、豊原敬文、鈴木健弘1、田中哲洋、阿部高明
- Organizer
  第44 回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 妊娠高血圧症候群における急性憎悪および症状遷延化因子の検討2022
- Author(s)
  飯田怜央、豊原敬文、岩間憲之、渡邉駿、菊地晃一、鈴木健弘、宮崎真理子、齋藤昌利、阿部高明
- Organizer
  第119回日本内科学会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 4.糖尿病性腎臓病の新規予後予測マーカーとしての尿中フェニル硫酸2022
- Author(s)
  菊地晃一、鯨井涼太、松本洋太郎、中村智洋、渡邉駿、三瀬広記、豊原敬文、鈴木健弘、和田淳、富岡佳久、阿部高明
- Organizer
  第65回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 患者由来iPS細胞を用いた新規動脈硬化抑制因子の発見と腎疾患への応用2021
- Author(s)
  豊原敬文
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] atient derived-iPS cells identify a novel protective factor against atherosclerosis.2021
- Author(s)
  Takafumi Toyohara, Shun Watanabe, Koichi Kikuchi, Takehiro Suzuki, Chad A. Cowan, Takaaki Abe.
- Organizer
  International Symposium on Atherosclerosis Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] CaSR刺激型自己抗体による副甲状腺機能低下症の合併が疑われた腎血管性高血圧の1例2021
- Author(s)
  上原啓誠、豊原敬文、三島英換、渡邉駿、菊地晃一、鈴木健弘、伊東伸朗、宮崎真理子、阿部高明
- Organizer
  第51回日本腎臓学会東部学術大会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 患者由来iPS細胞を用いた新規動脈硬化抑制因子の発見2021
- Author(s)
  豊原敬文、渡邉駿、菊地晃一、鈴木健弘、阿部高明
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 患者由来iPS細胞を用いた新規動脈硬化抑制因子の発見2021
- Author(s)
  豊原敬文、渡邉駿、菊地晃一、三島英換、鈴木健弘、阿部高明(共同演者)
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 尿中GDF15の糖尿病性腎症と腎内環境の予測因子としての有用性の臨床検討2021
- Author(s)
  大下冬馬、豊原敬文、渡邉駿、菊地晃一、鈴木健弘、鯨井涼太、宮崎真理子、富岡佳久、阿部高明
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] ケモカインレセプターCCR10を介した腸腎連関の調節と腎不全治療2021
- Author(s)
  一條　真梨子、鯨井　涼太、菊地晃一、秋山　由雅子、豊原　敬文、鈴木　健弘、阿部高明
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 血中・尿中GDF15の糖尿病性腎症及び腎内環境予測因子としての有用性の臨床検討2021
- Author(s)
  大下冬馬、豊原敬文、渡邉駿、菊地晃一、鈴木健弘、宮崎真理子、富岡佳久、阿部高明
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 腸内細菌叢と胆汁酸の調節による腎不全治療2021
- Author(s)
  秋山　由雅子、前川　正充、菊地　晃一、何　欣蓉、一條　真梨子、鈴木　千登世、渡邊　駿、豊原　敬文、鈴木　健弘、富岡　佳久、阿部高明
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] Patient derived-iPS cells identify a novel protective factor against atherosclerosis2021
- Author(s)
  Takafumi Toyohara, Shun Watanabe, Koichi Kikuchi, Takehiro Suzuki, Chad A. Cowan, Takaaki Abe
- Organizer
  The 19 th International Symposium on Atherosclerosis Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 血中・尿中GDF15の糖尿病性腎症及び腎内環境予測因子としての有用性の臨床検討2021
- Author(s)
  大下冬馬、豊原敬文、渡邉駿、菊地晃一、鈴木健弘、宮崎真理子、富岡佳久、阿部高明
- Organizer
  第64回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-21K08245
[Presentation] 血中・尿中GDF15の糖尿病性腎症及び腎内環境予測因子としての有用性の臨床検討2021
- Author(s)
  大下冬馬、豊原敬文、渡邉駿、菊地晃一、鯨井涼太、鈴木健弘、宮崎真理子、富岡佳久、阿部高明
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] 患者由来iPS細胞と動脈硬化モデルマウスを用いた新規動脈硬化抑制因子の発見2021
- Author(s)
  豊原敬文、渡邉駿、菊地晃一、鈴木健弘、阿部高明(共同演者)
- Organizer
  心血管代謝週間2021(Cardiovascular and metabolic week 2021)
- Data Source
  KAKENHI-PROJECT-21K08270
[Presentation] マウス急性腎障害モデルに対するヒトiPS細胞由来ネフロン前駆細胞を用いた細胞療法の確立2015
- Author(s)
  豊原敬文
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25860674
[Presentation] ヒト多能性幹細胞からネフロン構成細胞に分化する腎前駆細胞への分化誘導2014
- Author(s)
  豊原敬文
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-25860674
[Presentation] Development of differentiation methods from human iPSCs/ESCs into nephron progenitor cells2013
- Author(s)
  豊原敬文
- Organizer
  国際幹細胞学会（ISSCR）
- Place of Presentation
  ボストン（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-25860674
[Presentation] DEVELOPMENT OF DIFFERENTIATION METHODS FROM HUMAN IPSCS/ESCS INTO NEPHRON PROGENITOR CELLS2013
- Author(s)
  豊原敬文
- Organizer
  International Society for Stem Cell Research 11th Annual Meeting
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-23790937
[Presentation] DEVELOPMENT OF DIFFERENTIATION METHODSFROM HUMAN IPSCS/ESCS INTO NEPHRONPROGENITOR CELLS2013
- Author(s)
  Takafumi Toyohara, Yukiko Yamagishi,Shin-Ichi Mae, Tatsuyuki Inoue, ToshikazuAraoka, Tomoko Kasahara, Shinya Yamanaka,HidenoriNakajima, Kenji Osafune
- Organizer
  International Society for Stem CellResearch 11th Annual Meeting
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-23790937
[]

1. OSAFUNE Kenji (80502947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. Akiyama Yasutoshi (70635557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Suzuki Takehiro (50396438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
4. 神山篤史 (50647005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 渡辺和宏 (30569588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 新妻邦泰 (10643330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Rashad Sherif (00824088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 菅野新一郎 (10400417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森戸大介 (20514251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 阿部高明 (80292209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂田洋之 (80722305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHIDA Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. MATSUMOTO Yotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 原田成美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 鈴木貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 古本祥三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 清治和将

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 高瀬圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 森崇寧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 橋本潤一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 三島英換

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 石井直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 青木正志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toyohara Takafumi 豊原 敬文

TOYOHARA Takafumi 豊原 敬文

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Elucidating the pathological mechanism and developing the clinical markers for nephrosclerosis by iPS cellsPrincipal Investigator

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Elucidation of the pathogenesis of moyamoya disease through Endothelial-Smooth Muscle Interaction and RNF213

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Elucidation of the pathogenesis of ulcerative colitis using an early-onset model of human artificial intestine

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Profiling of modified nucleosides in mitochondrial tRNAs for diagnosis of mitochondrial diseases

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Development of novel therapy for diabetic nephropathy using lipid metabolismPrincipal Investigator

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Development of mitochondria homing drug for kidney disease

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Developing the differentiation methods from pluripotent stem cells to glomerular endothelial cells for diabetic researchPrincipal Investigator

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Development of cell therapy using hiPS-derived nephron progenitorsPrincipal Investigator

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Development of differentiation methods from human pluripotent stemcells into renal progenitor cellsPrincipal Investigator

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[Book] 再生医療における臨床研究と製品開発2013

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[Journal Article] Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease2023

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[Journal Article] “Coexistence of IgA nephropathy and renal artery stenosis in Takayasu arteritis: case report and literature review”2022

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[Journal Article] L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism2021

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[Journal Article] Fibromuscular dysplasia with recurrence after "long-term" following percutaneous transcatheter renal angioplasty: two case reports with a review of 26 patients2021

Toyohara Takafumi 豊原敬文

TOYOHARA Takafumi 豊原敬文