KIKUCHI Kazuya 菊地和也

Researcher Number	70292951
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院工学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪大学, 大学院工学研究科, 教授 2015 – 2021: 大阪大学, 工学研究科, 教授 2017: 大阪大学, 大学院工学研究科, 教授 2012 – 2015: 大阪大学, 工学(系)研究科(研究院), 教授 2013: 大阪大学, 大学院・工学研究科, 教授 … More 2012: 大阪大学, 大学院工学研究科, 教授 2011: 大阪大学, 大学院・工学研究科, 教授 2009 – 2010: Osaka University, 工学研究科, 教授 2008: 阪大, 工学(系)研究科(研究院), 教授 2007 – 2008: Osaka University, Graduate School of Engineering, Professor 2006: 大阪大学, 大学院工学研究科, 教授 2005: 大阪大学, 大学院・工学研究科, 教授 2000 – 2004: 東京大学, 大学院・薬学系研究科, 助教授 1999: 東京大学, 大学院・薬学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Science and Engineering / Medium-sized Section 37:Biomolecular chemistry and related fields / Science and Engineering / Biological Sciences / Living organism molecular science / Chemical biology / Chemistry related to living body / Chemical biology / Transformative Research Areas, Section (II) / 医薬分子機能学 / Bioorganic chemistry / Bio-related chemistry … More Except Principal Investigator … More Chemical biology / 医薬分子機能学 / Science and Engineering / Biophysics / Chemical pharmacy Less
Keywords	Principal Investigator MRI / 蛍光プローブ / イメージング / 蛋白質ラベル化 / 化学プローブ / 可視化 / in vivoイメージング / IP_3受容体 / 破骨細胞 / 蛍光センサー … More / Gd^<3+>錯体 / 超解像イメージング / タンパク質ラベル化 / 1分子イメージング / 蛍光イメージング / ランタノイド / 生体内分子 / 長寿命蛍光 / 遺伝子発現 / レーザー照射 / 細胞膜透過性 / イノシトール3リン酸 / レーザー分子不活化 / 生細胞イメージング / BLタグ / in vivo イメージング / 蛋白質修飾 / MRIプローブ / レーザー / IP_3 / 緩和時間 / 疎水性相互作用 / 細胞内Ca^<2+> / Zn^<2+>イオン / バイオイメージング / 蛍光共鳴エネルギー移動 / 化合物潜在空間 / PYPタグ / 光スイッチング / DNAメチル化 / fluorescent probe / クロモフォア / 可視化解析 / PTP / FRET / 低pH / オートファジー / シリカナノ粒子 / 蛍光 / 時間分解スペクトル / 希土類蛍光プローブ / 分子集合化 / マーカー遺伝子 / がん化プロセス / プローブ分子 / 配位空間変化 / MRI造影剤 / ランタノイド錯体 / 容量依存性Ca^<2+>流入 / アラキドン酸 / フルオレセイン / チロシンフォスファターゼ / 重なり積分 / レシオ測定 / Ca^<2+>流入 / 虚血 / 海馬 / 分子デザイン / 酵素反応 / RESORFT / フォトクロミック分子 / 蛍光スイッチング / pHプローブ / 二光子励起イメージング / 天然物有機化学 / ケミカルバイオロジー / 深層学習 / 生物活性分子 / 蛍光制御 / ゲノム動態可視化 / オルガネラ成熟 / 骨細胞 / 蛋白質局在 / pH計測 / 分子間相互作用解析 / 生物活性評価 / TLR4 / β-ラクタマーゼタグ / GLUT4 / 膜蛋白質 / RESOLFT / 蛋白質可逆ラベル化 / 光異性化 / 生理活性リガンド / 内在性膜タンパク質 / 時空間解析 / 内在性膜蛋白質 / 蛋白質分解 / エピゲノム / リジン脱メチル化酵素 / ヒストン脱アセチル化酵素 / エピジェネティクス / ヒストン脱メチル化酵素 / １分子イメージング / 光安定性 / signal transduction / excitation spectrum / phosphatase / fluorescence ratio imaging / イメージインテンシファイア / 蛍光顕微鏡 / 蛋白質相互作用 / calpain / シグナル伝達 / 励起スペクトル / 脱リン酸化酵素 / imaging / calcicum / inactiuation / receptor / laser / Probe / Fluorescence / 合成小分子 / 光照射 / 平滑筋 / Ca^<2+> / 小胞体 / タプシガルジン / カルシウムチャネル / 容量性Ca^<2+>流入 / 小分子CALI / カルシウム / 不活化 / 受容体 / プローブ / fluorescein / arachidonic acid / overlap integral / ehergy fransfer / ratio imaging / 歯状回 / CA1 / 亜鉛イオン / 平滑筋組織 / マクロCALI / クマリン / フルオレッセイン / レシオ測定法 / エネルギー移動 / レシオイメージング / BL-tag / pH感受性プローブ / ヒドロキシアパタイト / BODIPY / 二光子蛍光イメージング / ｐH感受性プローブ / 19F MRIプローブ / 19FMRI / 分子イメージング / pH応答性蛍光ラベル化プローブ / 蛋白質標識 / 合成蛍光プローブ / Caspase-3 / アポトーシス / ^<19>F-MRI / 配立化学 / 常磁性緩和促進効果 / ^<19>F / レポーター酵素 / β-lactamase変異体 / 発蛍光型プローブ / タグ蛋白質 / 蛋白質ラベル化法 / 蛋白質標識技術 / βラクタマーゼ変異体 / アゾピリジン / 蛍光標識 / 可視化プローブ / 生物無機化学 / β-galaCtOSidase / がん / 常磁性効果 / β-lactamase / ^<19>F-MRIプローブ / 光増感色素 / AMPA受容体 / NMDA受容体 / レーザー分子機能不活化 / caspase / 常磁性相互作用 / <19>^F / Gd3+ / 長波長励起蛍光増大型プローブ / 金属錯体 / タンパク質修飾 / 分子活性不活化 / 標的分子 / ランダノイド / 時間分解 / 配位空間 / ランタノイド金属錯体 / 縦緩和時間 / MRI プローブ / 蛍光性小分子化合物 / タグタンパク質 / β-ラクタマーゼ / タンパク質の標識 / 配位結合 / 水分子配位数 / 生体非侵襲 / 不活性化 / 生理条件 / CALI / 緩和時間変化 / 不活性 / 分子スイッチ / 時間分解蛍光測定法 / antenna / Eu^<3+> / Tb^<3+> / コントラスト / レポーター遺伝子 / ソフトな分子間相互作用 / 細胞内Ca^<2+>動態 / レーザー分子機能不活性化 / 中枢神経系 / 蛍光強度 / 配位子 / 低親和性 / 蛍光センサー分子 / 接触阻止 / カルシウムオシレーション / 膜透過 / 高親和性リガンド / 細胞内セカンドメッセンジャー / thapsigargin / 高機能性分子 / 組織標本 / Ca^<2+>放出 / Ca^<2+>ストア / 小分子プローグ / 蛍光図 / 生細胞 / 蛍光団 / 励起状態 / フォスフォジエステラーゼ / シクロデキストリン / リンカー / 非会合性色素 / グリーン蛍光タンパク質 / 低分子プローブ / 表面プラスモン共鳴 / 大腸菌発現系 / 細胞内カルシウム / アゴニスト / CALI用IP_3類縁体 / 生体機能探索分子 … More Except Principal Investigator 蛍光 / 一酸化窒素 / 生細胞イメージング / MRI / 蛍光プローブ / 蛍光顕微鏡 / 亜鉛 / バイオイメージング / photoinduced electron transfer / fluorescence / 活性酸素 / PET / FRET / プローブ / 生物活性リガンド / ケミカルバイオロジー / 天然物化学 / 分子社会学 / 化学コミュニケーション / 超分子 / 光安定性 / 希土類イオン / 光退色 / 蛍光色素 / 超分子化学 / 光制御 / 細胞内Mg2+ / 蛋白質ラベル化 / Mg2+ / タンパク質ラベル化 / 蛍光イメージング / Photoinduced electron Transfer / Near Infra-red Emission / Fluorescent Probe / Molecular Imaging / DAC / 超寿命蛍光 / 長寿命蛍光 / 可視化 / レシオ / 光誘起電子移動 / 近赤外発光 / 分子イメージング / neutrophiles / probe / inflammation / bioimaging / highly reactive oxygen species / 錯体 / 虚血 / 好中球 / 炎症 / reactive oxygenspecies / zinc ion / nitric oxide / hydrolase / probe bioimaging / ERET / 活性酵素 / 亜鉛イオン / 加水分解酵素 / enzyme model / inhibitor / oxidation / hydrogen bond / thiolate / porphyrin / NO synthase / Cytochrome p450 / 発現系 / 阻害剤 / アイソザイム / ペプチド / NO / ヘム / 過酸 / 活性腫 / ヘムーチオレート / 酵素阻害剤 / 水素結合 / 酸化 / ポルフィリン / チオレート / NO合成酵素 / シトクロムP450 Less

化学プローブのデザイン・合成が拓くin vivoイメージングPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
潜在空間を構成・検証する生物活性の時空間定量計測手法開発・応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Osaka University
Latent Chemical Space Based on Diverse Natural Products for Bio-active Molecular DesignArea Organizer
- Area Organizer
  
  菊地和也
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
天然物が織り成す化合物潜在空間が拓く生物活性分子デザインPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Osaka University
Super-resolution imaging probe using novel chemical switchPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Development of functional fluorescent probe for imaging osteocyte function and 4D nucleomicsPrincipal Investigator
- Principal Investigator
  
  Kazuya Kikuchi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Fluorescent super-resolution imaging probe using novel chemical switching mechanismPrincipal Investigator
- Principal Investigator
  
  Kikuchi Kazuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Analysis of membrane protein dynamics with chemical approachesPrincipal Investigator
- Principal Investigator
  
  Kikuchi Kazuya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
がん細胞転移を可視化するシステインプロテアーゼ蛍光プローブPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Understanding of chemical communications and higher-order functional evaluation of bioactive ligands by spatiotemporal analysisPrincipal Investigator
- Principal Investigator
  
  Kikuchi Kazuya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Frontiers in Chemical Communications
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Designed Chemical Probes for Clarification of Biological Function of Target MoleculesPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Fluorescence screening and imaging by chemical probes for detecting histone deacetylases/demethylases activityPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Development of Photostable Supramolecular Fluorophores and Application to Bioimaging
- Principal Investigator
  
  MIZUKAMI Shin
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Tohoku University
自動点滅する蛋白質ラベル化プローブ：１分子及び超解像顕微鏡応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Chemical probes for long time imaging of osteoclasts function by optimization of emission wavelength and photostabilityPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Imaging and photoregulation of cellular functions by using functional molecule-protein hybrid probes
- Principal Investigator
  
  MIZUKAMI Shin
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Tohoku University
生命分子機能を、時空間を制御して解明する設計分子プローブPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Design, Synthesis, and Biological Application of in vivo Imaging ProbesPrincipal Investigator
- Principal Investigator
  
  Kikuchi Kazuya
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
化学スイッチを組み込んだ分子プローブによる、PYPを用いた標的蛋白質機能解析Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
In vivo imaging probes for visualization of activated osteoclastsPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
分子フォトニクス制御に基づいた生命現象探索錯体プローブPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
分子フォトニクス制御に基づいた生命現象探索錯体プローブPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
可視化プローブの創製によるがん化プロセスのイメージングPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
機能性化学スイッチをデザインしたイメージング分子プローブの合成Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
緩和時間変化型MRIプローブのデザイン・合成・生物応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
Design, Synthesis and Biological Application of Chemical Probes for in vivo ImagingPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2008 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (S)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
生体シグナル可視化センシングPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
緩和時間変化型機能性MRIプローブのデザイン・合成・生物応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
生きたまま分子機能を不活化するレーザー分子機能不活化プローブの開発Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
可視化プローブの創製によるがん化プロセスのイメージングPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
分子プローブのデザイン・合成による細胞情報伝達に関わる蛋白質活性の可視化Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
金属錯体の配位空間制御を応用した生体機能可視化センサー分子Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
生体シグナル可視化センシングPrincipal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
合成小分子プローブを用いたレーザー分子機能不活化Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Design and synthesis of visualization sensor molecules for bio-imagingPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
分子プローブのデザイン・合成による細胞情報伝達に関わる蛋白質活性の可視化と不活化Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
金属錯体の配位空間制御を応用した生体機能可視化センサー分子Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
ソフトな分子間相互作用を応用した、生体内分子の可視化及び不活化センサー分子Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
MRIプローブのデザイン・合成によるin vivo可視化解析Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
受容体分子のレーザー分子不活化による膜インターフェイスにおけるシグナル変換制御Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of Bioimaging Probes For In Vivo Application
- Principal Investigator
  
  NAGANO Tetsuo
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
蛍光プローブの創製による,細胞応答の生きたままの状態での可視化Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
  The University of Tokyo
疎水性相互作用を利用した高機能性分子による細胞内分子のリアルタイム機能制御Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
短寿命励起鍵物質の蛍光発光原理解明と生細胞蛍光プローブへの応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
疎水性相互作用を利用した高機能性分子による細胞内分子のリアルタイム機能制御Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Mechanism Based Design of Fluorescent Probes for Biological ApplicationsPrincipal Investigator
- Principal Investigator
  
  KIKUSHI Kazuya
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
Desigh Syntlesis and Biological Application of Fluorescence ProbesPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kazuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
短寿命励起鍵分子の蛍光発光原理解明と生細胞蛍光プローブへの応用Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
STUDIES ON RATIONAL DESIGN PRINCIPLE FOR FLUORESCENCE ON/OFF SWITCHING
- Principal Investigator
  
  NAGANO Tetsuo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo
DEVELOPMENT OF FUNCTIONAL FLUORESCENT PROBES FOR BIOIMAGING
- Principal Investigator
  
  NAGANO Tetsuo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
生体機能探索分子を用いたイノシトール3リン酸受容体のレーザー分子不活化Principal Investigator
- Principal Investigator
  
  菊地和也
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
Investigation on the Chemical Property of Heme Thiolate Structure and Application to Medicinal Chemistry
- Principal Investigator
  
  HIGUCHI Tsunehiko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Nagoya City University
  The University of Tokyo

[Book] 先端の分析法第2版（原理編第3章プローブ, MRIプローブ）2022
- Author(s)
  蓑島維文、菊地和也
- Total Pages
  1072
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437374
- Data Source
  KAKENHI-PROJECT-18H03935
[Book] 先端の分析法第2版（原理編第3章プローブ, MRIプローブ）2022
- Author(s)
  蓑島維文、菊地和也
- Total Pages
  1072
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437374
- Data Source
  KAKENHI-PLANNED-17H06409
[Book] 先端の分析法第2版（原理編第3章プローブ, MRIプローブ）2022
- Author(s)
  蓑島維文、菊地和也
- Total Pages
  1072
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437374
- Data Source
  KAKENHI-PROJECT-19K22255
[Book] 核酸科学ハンドブック（第5章2　MRIプローブ）2020
- Author(s)
  蓑島維文、菊地和也
- Total Pages
  576
- Publisher
  講談社
- ISBN
  9784065207864
- Data Source
  KAKENHI-PLANNED-17H06409
[Book] 核酸科学ハンドブック（第5章2　MRIプローブ）2020
- Author(s)
  蓑島維文、菊地和也
- Total Pages
  576
- Publisher
  講談社
- ISBN
  9784065207864
- Data Source
  KAKENHI-PROJECT-19K22255
[Book] 【機器分析編】3.吸光・蛍光分析2011
- Author(s)
  井村久則・菊地和也・平山直紀・森田耕太郎・渡會仁
- Publisher
  共立出版社
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Rational Design of Hydroxylated Thiazole Orange Photocages for Green Light‐Triggered DNA Recombination2024
- Author(s)
  Hashimoto Ryu、Minoshima Masafumi、Kikuchi Kazuya
- Journal Title
  
  ChemBioChem
  
  Volume: 25 Issue: 4
- DOI
  10.1002/cbic.202300799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H04706
[Journal Article] Recent advancements of fluorescent biosensors using semisynthetic probes2024
- Author(s)
  Reja Shahi Imam、Minoshima Masafumi、Hori Yuichiro、Kikuchi Kazuya
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 247 Pages: 115862-115862
- DOI
  10.1016/j.bios.2023.115862
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-21K19048, KAKENHI-PUBLICLY-22H05425, KAKENHI-PLANNED-21H05075, KAKENHI-PROJECT-21H04706
[Journal Article] Activatable 19F MRI probe for detection of α-amylase activity2024
- Author(s)
  Konishi Yuki、Otera Yuya、Minoshima Masafumi、Kikuchi Kazuya
- Journal Title
  
  Chemistry Letters
  
  Volume: 53 Issue: 1
- DOI
  10.1093/chemle/upae003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-21H04706
[Journal Article] No-wash fluorogenic labeling of proteins for reversible photoswitching in live cells2024
- Author(s)
  Torii Kenji、Benson Sam、Hori Yuichiro、Vendrell Marc、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 15 Issue: 4 Pages: 1393-1401
- DOI
  10.1039/d3sc04953a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-21K19048, KAKENHI-PROJECT-22KJ2066, KAKENHI-PROJECT-20H02879, KAKENHI-PLANNED-21H05075, KAKENHI-PROJECT-21H04706
[Journal Article] 生命機能を可視化するさまざまな化学蛍光プローブ2023
- Author(s)
  蓑島維文、菊地和也
- Journal Title
  
  医学のあゆみ　生体イメージングの最前線
  
  Volume: 286 Pages: 337-342
- Data Source
  KAKENHI-PROJECT-23KK0106
[Journal Article] Variational autoencoder-based chemical latent space for large molecular structures with 3D complexity2023
- Author(s)
  Ochiai Toshiki、Inukai Tensei、Akiyama Manato、Furui Kairi、Ohue Masahito、Matsumori Nobuaki、Inuki Shinsuke、Uesugi Motonari、Sunazuka Toshiaki、Kikuchi Kazuya、Kakeya Hideaki、Sakakibara Yasubumi
- Journal Title
  
  Communications Chemistry
  
  Volume: 6 Issue: 1 Pages: 249-249
- DOI
  10.1038/s42004-023-01054-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-22K19115, KAKENHI-ORGANIZER-23H04880, KAKENHI-PLANNED-23H04882, KAKENHI-PLANNED-23H04885, KAKENHI-PLANNED-23H04887, KAKENHI-PROJECT-20H00405, KAKENHI-PROJECT-21H04706
[Journal Article] Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging2023
- Author(s)
  Konishi Yuki、Minoshima Masafumi、Fujihara Kohei、Uchihashi Takayuki、Kikuchi Kazuya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 62 Issue: 40
- DOI
  10.1002/anie.202308565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-21H04706
[Journal Article] 生命機能を可視化するさまざまな化学蛍光プローブ2023
- Author(s)
  蓑島維文、菊地和也
- Journal Title
  
  医学のあゆみ　生体イメージングの最前線
  
  Volume: 286 Pages: 337-342
- Data Source
  KAKENHI-PROJECT-21H04706
[Journal Article] Persistent Fluorescence Switching of a Probe Using a Photochromic Quencher with High Photostability Assisted by Protein-Surface Modification2023
- Author(s)
  Torii Kenji、Hori Yuichiro、Kikuchi Kazuya
- Journal Title
  
  Analytical Chemistry
  
  Volume: 95 Issue: 23 Pages: 8834-8841
- DOI
  10.1021/acs.analchem.3c00163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-21K19048, KAKENHI-PROJECT-22KJ2066, KAKENHI-PLANNED-21H05075, KAKENHI-PROJECT-21H04706
[Journal Article] Visualization of multiple localizations of GLUT4 by fluorescent probes of PYP-tag with designed unnatural warhead2023
- Author(s)
  Nishiura Miyako、Hori Yuichiro、Umeno Maho、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 14 Issue: 22 Pages: 5925-5935
- DOI
  10.1039/d3sc00724c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-21K19048, KAKENHI-PLANNED-21H05075, KAKENHI-PROJECT-20H02879, KAKENHI-PROJECT-21H04706
[Journal Article] Development of a Versatile Protein Labeling Tool for Live‐Cell Imaging Using Fluorescent β‐Lactamase Inhibitors2023
- Author(s)
  Minoshima Masafumi、Umeno Taro、Kadooka Kohei、Roux Margaux、Yamada Namiko、Kikuchi Kazuya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 62 Issue: 18
- DOI
  10.1002/anie.202301704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05747, KAKENHI-PUBLICLY-21H00401, KAKENHI-PROJECT-23KK0106, KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-21H04706
[Journal Article] Long-term imaging of intranuclear Mg<sup>2+</sup> dynamics during mitosis using a localized fluorescent probe2023
- Author(s)
  Matsui Yusuke、Kowada Toshiyuki、Ding Yi、Sahoo Priya Ranjan、Kikuchi Kazuya、Mizukami Shin
- Journal Title
  
  Chemical Communications
  
  Volume: 59 Issue: 46 Pages: 7048-7051
- DOI
  10.1039/d2cc05930d
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19096, KAKENHI-PROJECT-23KK0106, KAKENHI-PROJECT-21H04706
[Journal Article] カテプシンK活性の検出を目指したOff-Onスイッチング19F MRIナノプローブの開発2022
- Author(s)
  小西祐輝、杉原文徳、蓑島維文、菊地和也
- Journal Title
  
  日本分子イメージング学会機関誌
  
  Volume: 15 Pages: 29-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04706
[Journal Article] Photoinitiator‐Free Two‐Photon Polymerization of Biocompatible Materials for 3D Micro/Nanofabrication2022
- Author(s)
  Nakayama Atsushi、Kumamoto Yasuaki、Minoshima Masafumi、Kikuchi Kazuya、Taguchi Atsushi、Fujita Katsumasa
- Journal Title
  
  Advanced Optical Materials
  
  Volume: 10 Issue: 18 Pages: 2200474-2200474
- DOI
  10.1002/adom.202200474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-20K21130, KAKENHI-PUBLICLY-21H00401, KAKENHI-PROJECT-20H00210, KAKENHI-PROJECT-21H04706
[Journal Article] An “OFF-ON-OFF” fluorescence protein-labeling probe for real-time visualization of the degradation of short-lived proteins in cellular systems2022
- Author(s)
  Reja Shahi Imam、Hori Yuichiro、Kamikawa Takuya、Yamasaki Kohei、Nishiura Miyako、Bull Steven D.、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 13 Issue: 5 Pages: 1419-1427
- DOI
  10.1039/d1sc06274c
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19048, KAKENHI-PLANNED-21H05075, KAKENHI-PROJECT-20H02879, KAKENHI-PROJECT-21H04706
[Journal Article] pH‐Sensitive Polymethacrylates as Potential Contrast Agents in 19F MRI2022
- Author(s)
  Zalewski Mariusz、Janasik Dawid、Kapala Anna、Minoshima Masafumi、Sugihara Fuminori、Raj Wojciech、Pietrasik Joanna、Kikuchi Kazuya、Krawczyk Tomasz
- Journal Title
  
  Macromolecular Chemistry and Physics
  
  Volume: 223 Issue: 14 Pages: 2200027-2200027
- DOI
  10.1002/macp.202200027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-20K05747, KAKENHI-PUBLICLY-21H00401, KAKENHI-PROJECT-21H04706
[Journal Article] Efficient visible/NIR light-driven uncaging of hydroxylated thiazole orange-based caged compounds in aqueous media2022
- Author(s)
  Hashimoto Ryu、Minoshima Masafumi、Sakata Souhei、Ono Fumihito、Ishii Hirokazu、Watakabe Yuki、Nemoto Tomomi、Yanaka Saeko、Kato Koichi、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 13 Issue: 25 Pages: 7462-7467
- DOI
  10.1039/d2sc02364d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H05425, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H05669, KAKENHI-PROJECT-20K05747, KAKENHI-PUBLICLY-21H00401, KAKENHI-PROJECT-21H04706
[Journal Article] カテプシン K 活性の検出を目指した Off-On スイッチング 19F MRI ナノプローブの開発2022
- Author(s)
  小西祐輝、杉原文徳、蓑島維文、菊地和也
- Journal Title
  
  日本分子イメージング学会機関誌（JSMI Report）
  
  Volume: 15 Pages: 29-33
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06409
[Journal Article] カテプシン K 活性の検出を目指した Off-On スイッチング 19F MRI ナノプローブの開発2022
- Author(s)
  小西祐輝、杉原文徳、蓑島維文、菊地和也
- Journal Title
  
  日本分子イメージング学会機関誌（JSMI Report）
  
  Volume: 15 Pages: 29-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22255
[Journal Article] カテプシン K 活性の検出を目指した Off-On スイッチング 19F MRI ナノプローブの開発2022
- Author(s)
  小西祐輝、杉原文徳、蓑島維文、菊地和也
- Journal Title
  
  日本分子イメージング学会機関誌（JSMI Report）
  
  Volume: 15 Pages: 29-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03935
[Journal Article] Anti-Siglec-15 antibody suppresses bone resorption by inhibiting osteoclast multinucleation without attenuating bone formation2021
- Author(s)
  Tsukazaki Hiroyuki、Kikuta Junichi、Ao Tomoka、Morimoto Akito、Fukuda Chie、Tsuda Eisuke、Minoshima Masafumi、Kikuchi Kazuya、Kaito Takashi、Ishii Masaru
- Journal Title
  
  Bone
  
  Volume: 152 Pages: 116095-116095
- DOI
  10.1016/j.bone.2021.116095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-21H02716, KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-20K09479, KAKENHI-PROJECT-21H04706, KAKENHI-PUBLICLY-21H00401
[Journal Article] Development of Off-On Switching 19F MRI Probes for Cathepsin K Activity Detection2021
- Author(s)
  Konishi Yuki、Okunishi Atsuya、Sugihara Fuminori、Nakamura Tatsuya、Akazawa Kazuki、Minoshima Masafumi、Kikuchi Kazuya
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 94 Issue: 6 Pages: 1690-1694
- DOI
  10.1246/bcsj.20210099
- NAID
  130008066557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-21H04706, KAKENHI-PUBLICLY-21H00401
[Journal Article] Cardioluminescence in Transgenic Zebrafish Larvae: A Calcium Imaging Tool to Study Drug Effects and Pathological Modeling2021
- Author(s)
  Vicente Manuel、Salgado-Almario Jussep、Collins Michelle M.、Martinez-Sielva Antonio、Minoshima Masafumi、Kikuchi Kazuya、Domingo Beatriz、Llopis Juan
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 10 Pages: 1294-1294
- DOI
  10.3390/biomedicines9101294
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-21H04706, KAKENHI-PUBLICLY-21H00401
[Journal Article] A step towards gadolinium-free bioresponsive MRI contrast agent2021
- Author(s)
  Wyskocka-Gajda Marzena、Przypis Lukasz、Olesiejuk Monika、Krawczyk Tomasz、Kuznik Anna、Nawara Krzysztof、Minoshima Masafumi、Sugihara Fuminori、Kikuchi Kazuya、Kuznik Nikodem
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 211 Pages: 113086-113086
- DOI
  10.1016/j.ejmech.2020.113086
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18H03935
[Journal Article] Fluorogenic probes for detecting deacylase and demethylase activity towards post-translationally-modified lysine residues2021
- Author(s)
  Hori Yuichiro、Nishiura Miyako、Tao Tomomi、Baba Reisuke、Bull Steven D.、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 7 Pages: 2498-2503
- DOI
  10.1039/d0sc06551j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02210, KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-21H04706
[Journal Article] Near-infrared fluorescent probes: a next-generation tool for protein-labeling applications2021
- Author(s)
  Reja Shahi Imam、Minoshima Masafumi、Hori Yuichiro、Kikuchi Kazuya
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 10 Pages: 3437-3447
- DOI
  10.1039/d0sc04792a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02210, KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-21H04706, KAKENHI-PUBLICLY-21H00401
[Journal Article] Optical Manipulation of Subcellular Protein Translocation Using a Photoactivatable Covalent Labeling System2021
- Author(s)
  Kowada Toshiyuki、Arai Keisuke、Yoshimura Akimasa、Matsui Toshitaka、Kikuchi Kazuya、Mizukami Shin
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 60 Issue: 20 Pages: 11378-11383
- DOI
  10.1002/anie.202016684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05701, KAKENHI-PROJECT-20K05702, KAKENHI-PUBLICLY-19H05284, KAKENHI-PUBLICLY-20H05435, KAKENHI-PROJECT-18H02102, KAKENHI-PROJECT-17K05921, KAKENHI-PROJECT-19K22241, KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935, KAKENHI-PLANNED-17H06409, KAKENHI-PLANNED-21H05252, KAKENHI-PROJECT-21H04706
[Journal Article] Live-Cell Imaging of Protein Degradation Utilizing Designed Protein-Tag Mutant and Fluorescent Probe with Turn-Off Switch2020
- Author(s)
  Gao J, Hori Y, Takeuchi O, Kikuchi K
- Journal Title
  
  Bioconjug Chem
  
  Volume: 31 Issue: 3 Pages: 577-583
- DOI
  10.1021/acs.bioconjchem.9b00696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-19K22255, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-19J12178, KAKENHI-PLANNED-17H06409
[Journal Article] Development of photoswitchable fluorescent molecules using arylazopyrazole2020
- Author(s)
  Torii K, Hori Y, Watabe K, Kikuchi K
- Journal Title
  
  Bull Chem Soc Jpn.
  
  Volume: - Issue: 7 Pages: 821-824
- DOI
  10.1246/bcsj.20200077
- NAID
  130007879560
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-17H02210, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-18H03935
[Journal Article] An Acid‐Activatable Fluorescence Probe for Imaging Osteocytic Bone Resorption Activity in Deep Bone Cavities2020
- Author(s)
  Hashimoto Ryu、Minoshima Masafumi、Kikuta Junichi、Yari Shinya、Bull Steven D.、Ishii Masaru、Kikuchi Kazuya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Issue: 47 Pages: 20996-21000
- DOI
  10.1002/anie.202006388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18H03935
[Journal Article] Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis2020
- Author(s)
  Imamura Hiromi、Sakamoto Shuichiro、Yoshida Tomoki、Matsui Yusuke、Penuela Silvia、Laird Dale W、Mizukami Shin、Kikuchi Kazuya、Kakizuka Akira
- Journal Title
  
  eLife
  
  Volume: 9
- DOI
  10.7554/elife.61960
- NAID
  120006893984
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-19H03435, KAKENHI-PLANNED-20H05757, KAKENHI-PROJECT-20H03221
[Journal Article] Oxygen Functional Groups on MWCNT Surface as Critical Factor Boosting T2 Relaxation Rate of Water Protons: Towards Improved CNT-Based Contrast Agents2020
- Author(s)
  Tomczyk Mateusz Michal、Boncel Slawomir、Herman Artur、Krawczyk Tomasz、Jakobik-Kolon Agata、Pawlyta Miroslawa、Krzywiecki Maciej、Chrobak Artur、Minoshima Masafumi、Sugihara Fuminori、Kikuchi Kazuya、Kuznik Nikodem
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: 15 Pages: 7433-7450
- DOI
  10.2147/ijn.s257230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18H03935
[Journal Article] Development of Fluorogenic Probes for Rapid High-Contrast Imaging of Transient Nuclear Localization of Sirtuin 32020
- Author(s)
  Gao J, Hori Y, Shimomura T, Bordy M, Hasserodt J, Kikuchi K
- Journal Title
  
  Chembiochem
  
  Volume: 21 Issue: 5 Pages: 656-662
- DOI
  10.1002/cbic.201900568
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-19K22255, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-19J12178, KAKENHI-PLANNED-17H06409
[Journal Article] Engineered Protein-tag for Rapid Live-cell Fluorogenic Visualization of Proteins by Anionic Probes2020
- Author(s)
  Gao J, Hori Y, Nishiura M, Bordy M, Hasserodt J, Kikuchi K
- Journal Title
  
  Chem Lett
  
  Volume: 49 Issue: 3 Pages: 232-235
- DOI
  10.1246/cl.190875
- NAID
  130007805930
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-19J12178, KAKENHI-PLANNED-17H06409
[Journal Article] Sensing Peroxynitrite in Different Organelles of Murine RAW264.7 Macrophages With Coumarin-Based Fluorescent Probes2020
- Author(s)
  Weber Maria、Yamada Namiko、Tian Xue、Bull Steven D.、Minoshima Masafumi、Kikuchi Kazuya、Mackenzie Amanda B.、James Tony D.
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 8 Pages: 39-39
- DOI
  10.3389/fchem.2020.00039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Journal Article] A Photodeactivatable Antagonist for Controlling CREB-Dependent Gene Expression2020
- Author(s)
  Imoto Takuma、Minoshima Masafumi、Yokoyama Tatsushi、Emery Ben P.、Bull Steven D.、Bito Haruhiko、Kikuchi Kazuya
- Journal Title
  
  ACS Central Science
  
  Volume: 6 Issue: 10 Pages: 1813-1818
- DOI
  10.1021/acscentsci.0c00736
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05747, KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06312, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-18H03935
[Journal Article] Rapid no-wash labeling of PYP-tag proteins with reactive fluorogenic ligands affords stable fluorescent protein conjugates for long-term cell imaging studies2020
- Author(s)
  Kumar N, Hori, Y. Nishiura M, Kikuchi K
- Journal Title
  
  Chem Sci
  
  Volume: 11 Issue: 14 Pages: 3694-3701
- DOI
  10.1039/d0sc00499e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06409
[Journal Article] In Vivo Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps2019
- Author(s)
  Minoshima Masafumi、Kikuta Junichi、Omori Yuta、Seno Shigeto、Suehara Riko、Maeda Hiroki、Matsuda Hideo、Ishii Masaru、Kikuchi Kazuya
- Journal Title
  
  ACS Central Science
  
  Volume: 5 Issue: 6 Pages: 1059-1066
- DOI
  10.1021/acscentsci.9b00220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-19K17906, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-16K01933, KAKENHI-PLANNED-17H06409
[Journal Article] Development of an effective protein-labeling system based on smart fluorogenic probes2019
- Author(s)
  Reja SI, Minoshima M, Hori Y, Kikuchi K
- Journal Title
  
  J Biol Inorg Chem
  
  Volume: 24 Issue: 4 Pages: 443-455
- DOI
  10.1007/s00775-019-01669-y
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-16K01933
[Journal Article] Improvement in Photostability of Fluorescein by Lanthanide Ions Based on Energy Transfer-based Triplet State Quenching2019
- Author(s)
  Imoto Takuma、Muramatsu Masayasu、Miyasaka Hiroshi、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Chemistry Letters
  
  Volume: 48 Issue: 10 Pages: 1181-1184
- DOI
  10.1246/cl.190469
- NAID
  130007724070
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-19K22241
[Journal Article] SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism2019
- Author(s)
  Benson Sam、Fernandez Antonio、Barth Nicole D.、de Moliner Fabio、Horrocks Mathew H.、Herrington C. Simon、Abad Jose Luis、Delgado Antonio、Kelly Lisa、Chang Ziyuan、Feng Yi、Nishiura Miyako、Hori Yuichiro、Kikuchi Kazuya、Vendrell Marc
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 58 Issue: 21 Pages: 6911-6915
- DOI
  10.1002/anie.201900465
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PROJECT-18H03935
[Journal Article] Photolytic Release of a Caged Inhibitor of an Endogenous Transcription Factor Enables Optochemical Control of CREB-Mediated Gene Expression2019
- Author(s)
  Imoto Takuma、Kawase Akihiro、Minoshima Masafumi、Yokoyama Tatsushi、Bito Haruhiko、Kikuchi Kazuya
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 1 Pages: 22-25
- DOI
  10.1021/acs.orglett.9b03568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22255, KAKENHI-PLANNED-17H06312, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-18J12617, KAKENHI-PROJECT-16K01933, KAKENHI-PLANNED-17H06409
[Journal Article] Chemical Tools with Fluorescence Switches for Verifying Epigenetic Modifications2019
- Author(s)
  Hori Y, Kikuchi K
- Journal Title
  
  Acc Chem Res
  
  Volume: 52 Issue: 10 Pages: 2849-2857
- DOI
  10.1021/acs.accounts.9b00349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PUBLICLY-18H04735, KAKENHI-PLANNED-17H06409
[Journal Article] Perfluorocarbon-based 19F MRI Nanoprobes for In Vivo Multicolor Imaging2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Matsushita Hisashi, Mukai Hiroaki, Akimoto Rena, Minoshima Masafumi, Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Angewante Chemie International Edition
  
  Volume: 57 Pages: 16742-16747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18F18116
[Journal Article] Highly Sensitive Detection of Caspase-3/7 Activity in Living Mice Using Enzyme-Responsive 19F MRI Nanoprobes2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 29 Issue: 5 Pages: 1720-1728
- DOI
  10.1021/acs.bioconjchem.8b00167
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-16F16331, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-18H03935
[Journal Article] Dynamic Analyses of the Short-Term Effects of Different Bisphosphonates Using Intravital Two-Photon Microscopy2018
- Author(s)
  Kikuta Junichi、Shirazaki Mai、Sudo Takao、Mizuno Hiroki、Morimoto Akito、Suehara Riko、Minoshima Masafumi、Kikuchi Kazuya、Ishii Masaru
- Journal Title
  
  JBMR Plus
  
  Volume: 2 Issue: 6 Pages: 362-366
- DOI
  10.1002/jbm4.10057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01933, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-16H02619, KAKENHI-PROJECT-18F18116
[Journal Article] Sensing caspase-1 activity using activatable 19F MRI nanoprobes with improved turn-on kinetics2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Minoshima Masafumi、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 83 Pages: 11785-11788
- DOI
  10.1039/c8cc05381b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01933, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-16F16331, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-18H03935
[Journal Article] Perfluorocarbon-based 19F MRI Nanoprobes for In Vivo Multicolor Imaging2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Matsushita Hisashi, Mukai Hiroaki, Akimoto Rena, Minoshima Masafumi, Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Angewante Chemie International Edition
  
  Volume: 57 Pages: 16742-16747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25220207
[Journal Article] Perfluorocarbon‐Based 19F MRI Nanoprobes for In Vivo Multicolor Imaging2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Matsushita Hisashi、Mukai Hiroaki、Akimoto Rena、Minoshima Masafumi、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 51 Pages: 16742-16747
- DOI
  10.1002/anie.201810363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03935
[Journal Article] In vivo visualisation of different modes of action of biologic DMARDs inhibiting osteoclastic bone resorption2018
- Author(s)
  Matsuura Y, Kikuta J, Kishi Y, Hasegawa T, Okuzaki D, Hirano T, Minoshima M, Kikuchi K, Kumanogoh A, Ishii M
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 印刷中 Issue: 8 Pages: 1219-1225
- DOI
  10.1136/annrheumdis-2017-212880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05671, KAKENHI-PROJECT-16K01933, KAKENHI-PLANNED-17H06409, KAKENHI-PROJECT-16H02619, KAKENHI-PROJECT-18F18116
[Journal Article] Synthetic-Molecule/Protein Hybrid Probe with Fluorogenic Switch for Live-Cell Imaging of DNA Methylation2018
- Author(s)
  Yuichiro Hori, Norimichi Otomura, Ayuko Nishida, Miyako Nishiura, Maho Umeno, Isao Suetake, Kazuya Kikuchi
- Journal Title
  
  J Am Chem Soc
  
  Volume: 140 Issue: 5 Pages: 1686-1690
- DOI
  10.1021/jacs.7b09713
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26282215, KAKENHI-PUBLICLY-16H01428, KAKENHI-PROJECT-16K13088, KAKENHI-PROJECT-18K06095, KAKENHI-PROJECT-15K14418, KAKENHI-PUBLICLY-17H06005, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-17H02210, KAKENHI-PROJECT-18H03935
[Journal Article] Ratiometric Imaging of Intracellular Mg2+ Dynamics Using a Red Fluorescent Turn-off Probe and a Green Fluorescent Turn-on Probe2018
- Author(s)
  Matsui Yusuke、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Chemistry Letters
  
  Volume: 47 Issue: 1 Pages: 23-26
- DOI
  10.1246/cl.170918
- NAID
  130006302062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-16K13102, KAKENHI-PROJECT-25220207
[Journal Article] Perfluorocarbon-based 19F MRI Nanoprobes for In Vivo Multicolor Imaging2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Matsushita Hisashi, Mukai Hiroaki, Akimoto Rena, Minoshima Masafumi, Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Angewante Chemie International Edition
  
  Volume: 57 Pages: 16742-16747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06409
[Journal Article] Live‐Cell Imaging of DNA Methylation Based on Synthetic‐Molecule/Protein Hybrid Probe2018
- Author(s)
  Kumar Naresh、Hori Yuichiro、Kikuchi Kazuya
- Journal Title
  
  The Chemical Record
  
  Volume: 18 Issue: 12 Pages: 1672-1680
- DOI
  10.1002/tcr.201800039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PUBLICLY-17H06005, KAKENHI-PROJECT-16F16331, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-17H02210
[Journal Article] Perfluorocarbon-based 19F MRI Nanoprobes for In Vivo Multicolor Imaging2018
- Author(s)
  Akazawa Kazuki、Sugihara Fuminori、Nakamura Tatsuya、Matsushita Hisashi, Mukai Hiroaki, Akimoto Rena, Minoshima Masafumi, Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Angewante Chemie International Edition
  
  Volume: 57 Pages: 16742-16747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16F16331
[Journal Article] Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation2017
- Author(s)
  Matsui Yusuke、Sadhu Kalyan K.、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 77 Pages: 10644-10647
- DOI
  10.1039/c7cc06141b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-16K13102, KAKENHI-PROJECT-25220207
[Journal Article] Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor?Adaptor Molecular Dynamics2017
- Author(s)
  Sato Ryota、Kozuka Jun、Ueda Masahiro、Mishima Reiko、Kumagai Yutaro、Yoshimura Akimasa、Minoshima Masafumi、Mizukami Shin、Kikuchi Kazuya
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 139 Issue: 48 Pages: 17397-17404
- DOI
  10.1021/jacs.7b08262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00413, KAKENHI-PROJECT-16K01933, KAKENHI-PROJECT-17K15725, KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-16K13102, KAKENHI-PROJECT-25220207
[Journal Article] Visualization of long-term Mg2+ dynamics in apoptotic cells using a novel targetable fluorescent probe2017
- Author(s)
  Matsui Y, Funato Y, Imamura H, Miki H, Mizukami S, Kikuchi K
- Journal Title
  
  Chem Sci.
  
  Volume: 8 Issue: 12 Pages: 8255-8264
- DOI
  10.1039/c7sc03954a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14723, KAKENHI-PROJECT-17K19396, KAKENHI-PROJECT-26291042, KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-26460364, KAKENHI-PROJECT-16K13102, KAKENHI-PROJECT-16K14709, KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-17H04041
[Journal Article] Photostable and Photoswitching Fluorescent Dyes for Super-resolution Imaging2017
- Author(s)
  M. Minoshima, K. Kikuchi
- Journal Title
  
  Journal of Biological Inorganic Chemistry
  
  Volume: - Issue: 5 Pages: 1-14
- DOI
  10.1007/s00775-016-1435-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-15K12754, KAKENHI-PROJECT-16K13099, KAKENHI-PROJECT-26750371, KAKENHI-PROJECT-16K01933, KAKENHI-PUBLICLY-16H00768
[Journal Article] Enzyme-Triggered Compound Release using Functionalized Antimicrobial Peptide Derivatives2017
- Author(s)
  Shin Mizukami, Masayoshi Kashibe, Kengo Matsumoto, Yuichiro Hori, Kazuya Kikuchi
- Journal Title
  
  Chem. Sci.
  
  Volume: 8 Issue: 4 Pages: 3047-3053
- DOI
  10.1039/c6sc04435b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00818, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-15K12754, KAKENHI-PROJECT-16K13099, KAKENHI-PROJECT-16K13102, KAKENHI-PUBLICLY-16H00768
[Journal Article] Fluorogenic Probes Reveal a Role of GLUT4 N-glycosylation in Intracellular Trafficking2016
- Author(s)
  S. Hirayama, Y. Hori, Z. Benedek, T. Suzuki, K. Kikuchi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12 Issue: 10 Pages: 853-859
- DOI
  10.1038/nchembio.2156
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H00768, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-26282215, KAKENHI-PROJECT-15K12754, KAKENHI-PROJECT-16K13099
[Journal Article] Real-time intravital imaging of pH variation associated with osteoclast activity2016
- Author(s)
  H. Maeda, T. Kowada, J. Kikuta, M. Furuya, M. Shirazaki, S. Mizukami, M. Ishii & K. Kikuchi,
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12754
[Journal Article] Real-Time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  Hiroki Maeda, Toshiyuki Kowada, Junichi Kikuta, Masayuki Furuya, Mai Shirazaki, Shin Mizukami, Masaru Ishii, Kazuya Kikuchi
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 12 Issue: 8 Pages: 579-585
- DOI
  10.1038/nchembio.2096
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H00818, KAKENHI-PUBLICLY-15H01158, KAKENHI-PUBLICLY-16H00768, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-16H02619, KAKENHI-PROJECT-15H03120, KAKENHI-PROJECT-15H05671, KAKENHI-PROJECT-15K12754, KAKENHI-PROJECT-16K13099, KAKENHI-PROJECT-16K13102
[Journal Article] Design of a Protein tag and Fluorogenic Probe with Modular Structure for Live-Cell Imaging of Intracellular Proteins2016
- Author(s)
  Y. Kamikawa, Y. Hori, K. Yamashita, L. Jin, S. Hirayama, D.M. Standley & K. Kikuchi
- Journal Title
  
  Chemical Science
  
  Volume: 7 Issue: 1 Pages: 308-314
- DOI
  10.1039/c5sc02351c
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12754, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-26282215
[Journal Article] Fabrication of ‘Clickable’ Polyfluorene Nanowires with High Aspect Ratio as Biological Sensing Platforms2016
- Author(s)
  T. Wasin, K. Enomoto, T. Sakurai, V. Padalkar, H. Cheng, M. Tang, A. Horio, D., Sakamaki, M. Omichi, A. Saeki, K. Kikuchi, Y. Hori, A. Chiba, Y. Saito, T. Kamiya, M. Sugimoto, S. Seki
- Journal Title
  
  ACS Sensors
  
  Volume: 6 Issue: 6 Pages: 766-774
- DOI
  10.1021/acssensors.6b00070
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00768, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-26249145, KAKENHI-PROJECT-15K12754, KAKENHI-PROJECT-16K13099
[Journal Article] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  H. Maeda, T. Kowada, J. Kikuta, M. Furuya, M. Shirazaki, S. Mizukami, M, Ishii & K. Kikuchi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25220207
[Journal Article] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  H. Maeda, T. Kowada, J. Kikuta, M. Furuya, M. Shirazaki, S. Mizukami, M, Ishii & K. Kikuchi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102529
[Journal Article] Selective Labeling of Proteins on Living Cell Membranes Using Fluorescent Nanodiamond Probes.2016
- Author(s)
  Shingo Sotoma, Jun Iimura, Ryuji Igarashi, Koichiro M. Hirosawa, Hidenori Ohnishi, Shin Mizukami, Kazuya Kikuchi, Takahiro K. Fujiwara, Masahiro Shirakawa and Hidehito Tochio
- Journal Title
  
  Nanomaterials
  
  Volume: 6 Issue: 4 Pages: 56-56
- DOI
  10.3390/nano6040056
- NAID
  120005848250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461576, KAKENHI-PUBLICLY-15H01212, KAKENHI-PUBLICLY-26115707, KAKENHI-PROJECT-24685028, KAKENHI-PUBLICLY-15H00818, KAKENHI-PUBLICLY-15H01636, KAKENHI-PROJECT-15H03120
[Journal Article] 19F MRI Probes with Tunable Switches and Highly Sensitive 19F MRI Nano-probes2015
- Author(s)
  K. Kikuchi
- Journal Title
  
  Bulletein of the Chemical Society of Japan
  
  Volume: 88 Issue: 4 Pages: 518-522
- DOI
  10.1246/bcsj.20140392
- NAID
  130005064990
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25220207
[Journal Article] Redesign of Fluorogenic Labeling System to Improve Surface Charges, Brightness, and Binding Kinetics for Imaging Functional Localization of Bromodomains2015
- Author(s)
  Y. Hori, S. Hirayama, M. Sato & K. Kikuchi
- Journal Title
  
  Angewante Chemie International Edition
  
  Volume: 54 Issue: 48 Pages: 14368-14371
- DOI
  10.1002/anie.201506935
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12754, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-14J00755, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-26282215
[Journal Article] An Enzyme-Responsive Metal-Enhanced Near-Infrared Fluorescence Sensor Based on Functionalized Gold Nanoparticles2015
- Author(s)
  Zhanghua Zeng, Shin Mizukami, Katsumasa Fujita, Kazuya Kikuchi
- Journal Title
  
  Chem. Sci.
  
  Volume: 6 Issue: 8 Pages: 4934-4939
- DOI
  10.1039/c5sc01850a
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24685028, KAKENHI-PUBLICLY-15H00818, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-15H03120
[Journal Article] BODIPY-based probes for the fluorescence imaging of biomolecules in living cells2015
- Author(s)
  Toshiyuki Kowada, Hiroki Maeda, Kazuya Kikuchi
- Journal Title
  
  Chemical Society Reviews
  
  Volume: - Issue: 14 Pages: 4953-4972
- DOI
  10.1039/c5cs00030k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J00794, KAKENHI-PROJECT-15K12754, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-25220207
[Journal Article] Intramolecular Long-distance Nucleophilic Reactions as a Rapid Fluorogenic Switch Applicable to Detection of Enzymatic Activity2015
- Author(s)
  Reisuke BABA, Yuichiro HORI, Kazuya KIKUCHI
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 12 Pages: 4695-4702
- DOI
  10.1002/chem.201406093
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J00565, KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-25560403, KAKENHI-PROJECT-25620133, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-26282215
[Journal Article] Actavataqble 19F MRI nanoparticle probes for the detection of reducing environments2015
- Author(s)
  Nkamura, T., Matsushita, H., Sugihara, F., Yoshioka, Y., Mizukami, S. and Kikuchi, K.
- Journal Title
  
  Angewandte Chemi International Edition
  
  Volume: 54 Issue: 3 Pages: 1007-1010
- DOI
  10.1002/anie.201409365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-24651259, KAKENHI-PROJECT-24685028, KAKENHI-PROJECT-25620133, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-25220207
[Journal Article] Development of a Fluorogenic Probe Based on a DNA Staining Dye for Continuous Monitoring of the Histone Deacetylase Reaction2014
- Author(s)
  M. Minoshima, T. Matsumoto, and K. Kikuchi
- Journal Title
  
  Anal. Chem.
  
  Volume: 86 Issue: 15 Pages: 7925-7930
- DOI
  10.1021/ac501881s
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25220207, KAKENHI-PROJECT-25620133, KAKENHI-PUBLICLY-26102529, KAKENHI-PROJECT-26750371
[Journal Article] ^1H MRI Detection of Gene Expression in Living Cells by Using Protein Tag and Biotinylation Probe2014
- Author(s)
  Akimasa Yoshimura, Shin Mizukami, Yuki Mori, Yoshichika Yoshioka, Kazuya Kikuchi
- Journal Title
  
  Chemistry Letters
  
  Volume: 43 Issue: 2 Pages: 219-221
- DOI
  10.1246/cl.130942
- NAID
  130004867962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00880, KAKENHI-PUBLICLY-24108724, KAKENHI-PROJECT-24249077
[Journal Article] Small-Molecule-Based Protein-Labeling Technology in Live Cell Studies : Probe-Design Concepts and Applications2013
- Author(s)
  S. Mizumkami, Y. Hori & K. Kikuchi
- Journal Title
  
  Acc. Chem. Res
  
  Volume: 46(in press) Issue: 1 Pages: 247-256
- DOI
  10.1021/ar400135f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PUBLICLY-24115513, KAKENHI-PROJECT-24651259, KAKENHI-PROJECT-24685028
[Journal Article] Development of Fluorogenic Probes for Quick No-Wash Live-Cell Imaging of Intracellular Proteins2013
- Author(s)
  Y. Hori, T. Norinobu, M. Sato, K. Arita, S. Shirakawa & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 135 Issue: 33 Pages: 12360-12365
- DOI
  10.1021/ja405745v
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PLANNED-21121006, KAKENHI-PROJECT-22685016, KAKENHI-PUBLICLY-24108724, KAKENHI-PUBLICLY-24113711
[Journal Article] Multifunctional Core-shell Silica Nanoparticles for Highly Sensitive ^<19>F MRI2013
- Author(s)
  H. Matsushita, S. Mizukami, F. Sugihara, Y. Nakanishi, Y. Yoshioka & K. Kikuchi
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 52(in press) Issue: 4 Pages: 52-52
- DOI
  10.1002/anie.201308500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PUBLICLY-24115513, KAKENHI-PROJECT-24651259, KAKENHI-PROJECT-24685028, KAKENHI-PROJECT-25620133
[Journal Article] Development of Luminescent Coelenterazine Derivatives Activatable by β-Galactosidase for Monitoring Dual Gene Expression2013
- Author(s)
  Lindberg E, Mizukami S, Ibata K, Miyawaki A, Kikuchi K
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 19 Issue: 44 Pages: 14970-14976
- DOI
  10.1002/chem.201302002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700387, KAKENHI-PUBLICLY-24115513, KAKENHI-PROJECT-24651259, KAKENHI-PROJECT-24685028, KAKENHI-PROJECT-25620133
[Journal Article] Fluorescent Probe for Detection of His tone Deacetylase Activity Based on Aggregation-Induced Emission2012
- Author(s)
  Dhara, K., Hori, Y., Baba, R, Kikuchi, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 48 Issue: 94 Pages: 11534-11536
- DOI
  10.1039/c2cc36591j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10F00338, KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-22685016, KAKENHI-PUBLICLY-23114710
[Journal Article] Switchable MRI Contrast Agents Based on Morphological Changes of pH-responsive Polymers2012
- Author(s)
  S. Okada, S. Mizukami & K. Kikuchi
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20 Issue: 2 Pages: 769-774
- DOI
  10.1016/j.bmc.2011.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-21685019
[Journal Article] Development of Fluorogenic Probe with Transesterification Switch for Detection of Histone Deacetylase Activity2012
- Author(s)
  R. Baba, Y. Hori, S. Mizukami & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 134 Issue: 35 Pages: 14310-14313
- DOI
  10.1021/ja306045j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-22685016, KAKENHI-PUBLICLY-24108724, KAKENHI-PUBLICLY-23114710
[Journal Article] Simple and Real-time Colorimetric Assay for Glycosidases Activity Using Functionalized Gold Nanoparticles and Its Application for Inhibitor Screening2012
- Author(s)
  Z. Zeng, S. Mizukami & K. Kikuchi
- Journal Title
  
  Anal. Chem.
  
  Volume: 84 Issue: 21 Pages: 9089-9085
- DOI
  10.1021/ac301677v
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-24685028, KAKENHI-PUBLICLY-24115513
[Journal Article] No-Wash Protein Labeling with Designed Fluorogenic Probes and Application to Real-Time Pulse-Chase Analysis2012
- Author(s)
  S. Mizukami, S. Watanabe, Y. Akimoto & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 134 Issue: 3 Pages: 1623-1629
- DOI
  10.1021/ja208290f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-21685019
[Journal Article] A New Approach for Fluorogenic Protein Labeling Via Photoinduced Electron Transfer Based BL-tag Protein Labeling Method2012
- Author(s)
  K. K. Sadhu, S. Mizukami, C. R. Lanam & K. Kikuchi
- Journal Title
  
  Chem. Asia. J.
  
  Volume: 7 Issue: 2 Pages: 272-276
- DOI
  10.1002/asia.201290001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] ^<19>F MRI monitoring of Gene Expression in Living Cells via Cell Surface β-Lactamase Activity2012
- Author(s)
  松下尚嗣、水上進、杉原文徳、白川昌宏、菊地和也
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Issue: 11 Pages: 1579-1583
- DOI
  10.1002/cbic.201200331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00895, KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-22613004, KAKENHI-PUBLICLY-24108724, KAKENHI-PROJECT-24651259, KAKENHI-PROJECT-24685028, KAKENHI-PUBLICLY-24115513
[Journal Article] Development of Protein-Labeling Probes with Redesigned Fluorogenic Switch Based on Intramolecular Association for No-wash Live-cell Imaging2012
- Author(s)
  Hori, Y., Nakaki, K., Sato, M., Mizukami, S., Kikuchi, K.
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: (In press) Issue: 23 Pages: 5611-5614
- DOI
  10.1002/anie.201200867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651237, KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-22685016, KAKENHI-PUBLICLY-23114710
[Journal Article] Covalent Protein Labeling with a Lanthanide Complex and its Application to Photoluminescence Lifetime-based Multicolor Bioimaging2011
- Author(s)
  Shin Mizukami, Taku Yamamoto, Akimasa Yoshimura, Shuji Watanabe, Kazuya Kikuchi
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 50 Issue: 37 Pages: 8750-8752
- DOI
  10.1002/ange.201103775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PUBLICLY-22108519
[Journal Article] Covalent Protein Labeling with a Lanthanide Complex and its Application to Photoluminescence Lifetimebased Multicolor Bioimaging2011
- Author(s)
  S. Mizukami, T. Yamamoto, A. Yoshimura, S. Watanabe & K. Kikuchi
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 50 Issue: 37 Pages: 8750-8752
- DOI
  10.1002/anie.201103775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-21685019
[Journal Article] ^<19>F MRI Detection of β-Galactosidase Activity for Imaging of Gene Expression2011
- Author(s)
  Shin Mizukami, Hisashi Matsushita, Rika Takikawa, Fuminori Sugihara, Masahiro Shirakawa, Kazuya Kikuchi
- Journal Title
  
  Chem.Sci.
  
  Volume: 2 Issue: 6 Pages: 1151-1155
- DOI
  10.1039/c1sc00071c
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22108519
[Journal Article] Cell Surface Protein Labeling with Luminescent Nanoparticles via Biotinylation Using Mutant ss-Lactamase-tag Technology2011
- Author(s)
  Akimasa Yoshimura, Shin Mizukami, Yuichiro Hori, Kazuya Kikuchi
- Journal Title
  
  ChemBioChem
  
  Volume: 12 Issue: 7 Pages: 1031-1034
- DOI
  10.1002/cbic.201100021
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22108519
[Journal Article] Intracellular Protein Labeling with Prodrug-Like Probes Using a Mutant β-Lactamase Tag2011
- Author(s)
  Shuji Watanabe, Shin Mizukami, Yuri Akimoto, Yuichiro Hori, Kazuya Kikuchi
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 17 Issue: 30 Pages: 8342-8349
- DOI
  10.1002/chem.201100973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-21685019
[Journal Article] In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts2011
- Author(s)
  T. Kowada, J. Kikuta, A. Kubo, M. Ishii, H. Maeda, S. Mizukami & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 133 Issue: 44 Pages: 17772-17776
- DOI
  10.1021/ja2064582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PLANNED-22113007, KAKENHI-PROJECT-22689030
[Journal Article] Photocontrolled Compound Release System Using Caged Antimicrobial Peptide2010
- Author(s)
  S. Mizukami, M. Hosoda, T. Satake, S. Okada, Y. Hori, T. Furuta & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 132 Issue: 28 Pages: 9524-9525
- DOI
  10.1021/ja102167m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004, KAKENHI-PROJECT-22310141
[Journal Article] Photocontrolled Compound Release System Using Caged Antimicrobial Peptide2010
- Author(s)
  S.Mizukami, M.Hosoda, T.Satake, S.Okada, Y.Hori, T.Furuta, K.Kikuchi
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 9524-9525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Dual Functional Probe to Detect Protease Activity for Fluorescence Measurement and ^<19>F MRI2009
- Author(s)
  S.Mizukami, R.Takikawa, F.Sugihara, M.Shirakawa, K.Kikuchi
- Journal Title
  
  Angew.Chem.Int.Ed. 48
  
  Pages: 3641-3643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Photoactive Yellow Protein- Based Protein Labeling System with Turn-on Fluorescence Intensity2009
- Author(s)
  Y. Hori, H. Ueno, S.Mizukami & K. Kikuchi,
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 131 Issue: 46 Pages: 16610-16611
- DOI
  10.1021/ja904800k
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Photoactive Yellow Protein-Based Protein Labeling System with Turn-on Fluorescence Intensity2009
- Author(s)
  Y.Hori, H.Ueno, S.Mizukami, K.Kikuchi
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 16610-16611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Covalent Protein Labeling Based on Non-catalytic・-Lactamase and a Designed FRET Substrate2009
- Author(s)
  S.Mizukami, S.Watanabe, Y.Hori, K.Kikuchi
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 5016-5017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Anion sensor-based ratiometric peptide probe for protein kinase activity2009
- Author(s)
  Kazuya Kikuchi
- Journal Title
  
  Organic Letters 11
  
  Pages: 2732-2735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Covalent Protein Labeling Based on Non-catalytic β-Lactamase and a Designed FRET Substrate2009
- Author(s)
  S. Mizukami, S. Watanabe, Y. Hori & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 131 Issue: 14 Pages: 5016-5017
- DOI
  10.1021/ja8082285
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Anion sensor-based ratiometric peptide probe for protein kinase activity2009
- Author(s)
  Kazuya Kikuchi
- Journal Title
  
  Organic Letters 11
  
  Pages: 2732-2735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20011005
[Journal Article] Dual Functional Probe to Detect Protease Activity for Fluorescence Measurement and ^<19>F MRI2009
- Author(s)
  S. Mizukami, R. Takikawa, F. Sugihara, M. Shirakawa & K. Kikuchi
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 48 Issue: 20 Pages: 3641-3643
- DOI
  10.1002/anie.200806328
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) phenomenon2008
- Author(s)
  K., Hanaoaka・K., Kikuchi・T., Terai・T., Komatsu・T., Nagano
- Journal Title
  
  Chemistry-A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Paramagnetic Relaxation-based ^<19>F MRI Probe to Detect Protease Activity2008
- Author(s)
  S. Mizukami, R. Takikawa, F. Sugihara, Y. Hori, H. Tochio, M. Walchli, M. Shirakawa & K. Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651093
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) phenomenon2008
- Author(s)
  K., Hanaoaka・K., Kikuchi・T., Terai・T., Komatsu・T., Nagano
- Journal Title
  
  Chemistry-A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  Yogo, T., Urano, U., Mizushima, A., Sunahara, H., Inoue, T., Hirose, K., Iilo, M., Kikuchi, K., Nagano, T.
- Journal Title
  
  Proceedings of the National Academy of Sciences 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Paramagnetic Relaxation-based ^<19>F MRI Probe to Detect Protease Activity2008
- Author(s)
  S. Mizukami, R. Takikawa, F. Sugihara, Y. Hori, H. Tochio, M. Walchli, M. Shirakawa & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 130 Issue: 3 Pages: 794-795
- DOI
  10.1021/ja077058z
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T. Yogo, Y. Urano, A. Mizushima, H. Sunahara, T. Inoue, K. Hirose, M. Iino, K. Kikuchi, T. Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement(RIME)phenomenon2008
- Author(s)
  K. Hanaoka, K. Kikuchi, T. Terai, T. Komatsu & T. Nagano
- Journal Title
  
  Chemistry-A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T., Yogo・Y., Urano・A., Mizushima・H., Sunahara・T., Inoue・K., Hirose・M., Iino・K., Kikuchi・T., Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Selective Photoinactivation of Protein Function through Environmentsensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T. Yogo, Y. Urano, A. Mizushima, H. Sunahara, T. Inoue, K. Hirose, M. Iino, K. Kikuchi, T. Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651093
[Journal Article] Paramagnetic Relaxation-based <19>^F MRI Probe to Detect Protease Activity2008
- Author(s)
  S., Mizukami・R., Takikawa・F., Sugihara・Y., Hori・H., Tochio・M., Walchli・M., Shirakawa・K., Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) Phenomenon2008
- Author(s)
  Kenjiro Hanaoka, Kazuya Kikuchi, Takuya Terai, Toru Komatsu, Tetsuo Nagano
- Journal Title
  
  Chemistry - A European Journal 3
  
  Pages: 987-995
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Selective Photoinactivation of Protein Function through Environmentsensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T., Yogo・Y., Urano・A., Mizushima・H., Sunahara・T., Inoue・K., Hirose・M., Iino・K., Kikuchi・T., Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Paramagnetic Relaxation-based 19F MRI Probe to Detect Protease Activity2008
- Author(s)
  S. Mizukami, R. Takikawa, F. Sugihara, Y. Hori, H. Tochio, M. Walchli, M. Shirakawa & K. Kikuchi
- Journal Title
  
  Journal of the Ameirican Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Paramagnetic Relaxation-based ^<19>F MRI Probe to Detect Protease Activity2008
- Author(s)
  S.Mizukami, R.Takikawa, F.Sugihara, Y.Hori, H.Tochio, M.Walchli, M.Shirakawa, K.Kikuchi
- Journal Title
  
  J.Am.Chem.Soc. 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  Yogo, T., Urano, U., Mizushima, A., Sunahara, H., Inoue, T., Hirose, K., Iino, M., Kikuchi, K., Nagano, T.
- Journal Title
  
  Proceedings of the National Academy of Sciences 105
  
  Pages: 28-32
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Paramagnetic Relaxation-based <19>^F MRI Probe to Detect Protease Activity2008
- Author(s)
  S., Mizukami・R., Takikawa・F., Sugihara・Y., Hori・H., Tochio・M., Walchli・M., Shirakawa・K., Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Lanthanide-based Protease Activity Sensors for Time-resolved Fluorescence Measurements2008
- Author(s)
  S. Mizukami, K. Tonai, M. Kaneko & K. Kikuchi
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 130 Issue: 44 Pages: 14376-14377
- DOI
  10.1021/ja800322b
- Data Source
  KAKENHI-PROJECT-20675004
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T, Yogo・Y, Urano・A, Mizushima・H, Sunahara・T, Inoue・K, Hirose・M, lino・K, Kikuchi・T, Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19036012
[Journal Article] A Gd3+ Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) Phenomenon2008
- Author(s)
  K, Hanaoka・K, Kikuchi・T, Terai・T, Komatsu & T. Nagano
- Journal Title
  
  Chemistry - A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19036012
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) phenomenon2008
- Author(s)
  K., Hanaoka・K., Kikuchi・T., Terai・T., Komatsu・T., Nagano
- Journal Title
  
  Chemistry - A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Selective Photoinactivation of Protein Function through Environmentsensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T., Yogo・Y., Urano・A., Mizushima・H., Sunahara・T., Inoue・K., Hirose・M., Iino・K., Kikuchi・T., Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 150
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Paramagnetic Relaxation-based <19>^F MRI Probe to Detect Protease Activity2008
- Author(s)
  S. Mizukami・R., Takikawa・F., Sugihara・Y., Hori・H., Tochio・M., Walchli・M., Shirakawa・K., Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] A Gd^<3+>-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) Phenomenon2008
- Author(s)
  Hanaoka, K., Kikuchi, K., Terai, T., Komatsu, T., Nagano, T.
- Journal Title
  
  Chemistry-A European Journal 3
  
  Pages: 987-995
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Paramagnetic Relaxation-based 19F MRI Probe to Detect Protease Activity2008
- Author(s)
  S, Mizukami・R, Takikawa・F, Sugihara・Y, Hori・H, Tochio・M, Walchli・M, Shirakawa &K, Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021028
[Journal Article] A Gd^3+-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement(RIME)Phenomenon2008
- Author(s)
  Hanaoka, K., Kikuchi, K., Terai, T., Komatsu, T., Nagano, T.
- Journal Title
  
  Chemistry-A European Journal 3
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer2008
- Author(s)
  T, Yogo・Y, Urano・A, Mizushima・H, Sunahara・T, Inoue・K, Hirose・M, lino・K, Kikuchi・T, Nagano
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 105
  
  Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021028
[Journal Article] Lanthanide-based Protease Activity Sensors for Time-resolved Fluorescence Measurements2008
- Author(s)
  S. Mizukami, K. Tonai, M. Kaneko, K. Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651093
[Journal Article] A Ga3+Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) phenomenon2008
- Author(s)
  K, Hanaoka・K, Kikuchi・T, Terai・T, Komatsu &T, Nagano
- Journal Title
  
  Chemistry- A European Journal 14
  
  Pages: 987-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021028
[Journal Article] Paramagnetic Relaxation-based 19F MRI Probe to Detect Protease Activity2008
- Author(s)
  S, Mizukami・R, Takikawa・F, Sugihara・Y, Hori・H, Tochio・M, Walchli・M, Shirakawa・K, Kikuchi
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 794-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19036012
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with New Microscopy System2007
- Author(s)
  K, Hanaoaka・K, Kikuchi・S, Kobayashi & T, Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19036012
[Journal Article] Iron Hydroxide Nanoparticles Coated With Poly (ethylene glycol)-poly (aspartic acid) Block Copolymer As Novel Magnetic Resonance Contrast Agents For In Vivo Cancer Imaging2007
- Author(s)
  Kumagai, M., Imai, Y., Nakamura, T., Yamasaki, Y., Sekino, M., Ueno, S., Hanaoka, K., Kikuchi, K., Nagano, T., Kaneko, E., Shimokado, K., Kataoka, K.
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces 56
  
  Pages: 174-181
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K., Hanaoaka・K., Kikuchi・S., Kobayashi・T., Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Time-Resolved Long-Lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  Hanaoka, K., Kikuchi, K., Kobayashi, S., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K., Hanaoaka・K., Kikuchi・S., Kobayashi・T., Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K. Hanaoaka, K. Kikuchi, S. Kobayashi & T. Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651093
[Journal Article] Iron Hydroxide Nanoparticles Coated With Poly(ethylene glycol)-poly(aspartic acid)Block Copolymer As Novel Magnetic Resonance Contrast Agents For In Vivo Cancer Imaging2007
- Author(s)
  Kumagai, M., Imai, Y., Nakamura, T., Yamasaki, Y., Sekino, M., Ueno, S., Hanaoka, K., Kikuchi, K., Nagano, T., Kaneko, E., Shimokado, K., Kataoka, K.
- Journal Title
  
  Colloids and Surfaces B:Biointerfaces 56
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K, Hanaoaka・K., Kikuchi・S., Kobayashi・T., Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Time-Resolved Long-Lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  Kenjiro Hanaoka, Kazuya Kikuchi, Shigeru Kobayashi, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 13502-13509
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K. Hanaoaka, K. Kikuchi, S. Kobayashi & T. Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System2007
- Author(s)
  K, Hanaoaka・K, Kikuchi・S, Kobayshi & T, Nagano
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 13502-13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021028
[Journal Article] Iron Hydroxide Nanoparticles Coated With Poly(ethylene glycol)-poly(aspartic acid) Block Copolymer As Novel Magnetic Resonance Contrast Agents For In Vivo Cancer Imaging2007
- Author(s)
  Michiaki Kumagai, Yutaka Imai, Teisaku Nakamura, Yuichi Yamasaki, Masaki Sekino, Shoogo Ueno, Kenjiro Hanaoka, Kazuya Kikuchi, Tetsuo Nagano, Eiji Kaneko, Kentaro Shimokado, Kazunori Kataoka
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 56
  
  Pages: 174-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  Terai, T., Kikuchi, K., Iwasawa, S., Kawabe, T., Hirata, Y., Urano. Y., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 128
  
  Pages: 6938-6946
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and <65>^Zn^<2+>Uptake2006
- Author(s)
  Robert A. Colvin, Charles P. Fontaine, Dustin Thomas, Tomoya Hirano, Tetsuo. Nagano, Kazuya Kikuchi
- Journal Title
  
  Arch. Biochem. Biophys 442
  
  Pages: 222-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change.2006
- Author(s)
  T.Komatsu, K Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation.2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J.Neurosci.Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Modulation of Luminescence Intensity of. Lanthanide Complexes by Photoinduced, Electron Transfer and Its. Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K.Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18655071
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released from Mossy Terminals During Tetanic Stimulation.2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Natano, N.Oku, A.Takeda
- Journal Title
  
  J.Neurosci.Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18655071
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K.Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18038028
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation.2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J.Neurosci.Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Inhibition of Presynaptic Activity tivity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18038028
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  Toru Komatsu, Kazuya Kikuchi, Hideo Takakusa, Kenjiro Hanaoka, Tasuku Ueno, Mako Kamiya, Yasuteru Urano, Tetsuo Nagano
- Journal Title
  
  J. Am Chem. Soc. 128
  
  Pages: 15946-15947
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation.2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J.Neurosci.Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K.Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18038028
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  Takuya Terai, Kazuya Kikuchi, Shin-ya Iwasawa, Takao Kawabe, Yasunobu Hirata, Yasuteru Urano, Tetsuo Nagano
- Journal Title
  
  J. Am Chem. Soc. 128
  
  Pages: 6938-6946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18033034
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18655071
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  Komatsu, T., Kikuchi, K., Takakusa, H., Hanaoka, K., Ueno, T., Kamiya, M., Urano, Y., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 128
  
  Pages: 15946-15947
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J. Neurosci. Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-18655071
[Journal Article] Toward Bifunctional Antibody Catalysis2006
- Author(s)
  K.Kikuchi, R.B.Hannak, M.J.Guo, A.J.Kirby, D.Hilvert
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 6189-6196
- Data Source
  KAKENHI-PROJECT-18032045
[Journal Article] Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation.2006
- Author(s)
  A.Minami, N.Sakurada, S.Fuke, K.Kikuchi, T.Nagano, N.Oku, A.Takeda
- Journal Title
  
  J.Neurosci.Res. 83
  
  Pages: 167-176
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K.Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change2006
- Author(s)
  T.Komatsu, K.Kikuchi, H.Takakusa, K.Hanaoka, T.Ueno, M.Kamiya, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 15946-15947
- Data Source
  KAKENHI-PROJECT-18310144
[Journal Article] Evidence for pH Dependent Zn^<2+>Influx in K562 Erythroleukemia Cells: Studies Using ZnAF-2F Fluorescence and 65Zn^<2+> Uptake2006
- Author(s)
  Colvin, R., Fontaine, C., Thomas, D., Hirano, T., Nagano, T., Kikuchi, K.
- Journal Title
  
  Archives of Biochemistry and Biophysics 442
  
  Pages: 222-228
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced, Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18011005
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-18038028
[Journal Article] Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe2006
- Author(s)
  T.Terai, K.Kikuchi, S.Iwasawa, T.Kawabe, Y.Hirata, Y.Urano, T.Nagano
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 6938-6946
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and Zn^<-65(2+)> Uptake.2005
- Author(s)
  R.A.Colvin, P.Fontaine, D.Thomas, T.Hirano, T.Nagano, K.Kikuchi
- Journal Title
  
  Arch.Biochem.Biophys. 442
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Inhibition of Autotaxin by Lysophosphatidic Acid and Sphiagosine-1-phosphate.2005
- Author(s)
  L.A.van Meeteren, P.Ruurs, E.Christodoulou, J.W.Coding, H.Takakusa, K.Kikuchi, A.Perrakis, T.Nagano, W.H.Moolenaar
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 21155-21161
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications2005
- Author(s)
  Eri Kawabata, Kazuya Kikuchi, Yasuteru Urano,. Hirotatsu Kojima, Akira Odani, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 818-819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications2005
- Author(s)
  E.Kawabata, K.Kikuchi, Y.Urano, H.Kojima, A.Odani, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 818-819
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phosphate.2005
- Author(s)
  L.A.van Meeteren, P.Rurns, E.Christodoulou, J.W.Goding, H.Takakusa, K.Kikuchi, A.Perrakis, T.Nagano, W.H.Moolenaar
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 21155-21161
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phosphate.2005
- Author(s)
  L.A.van Meeteren, P.Rurns, E.Christodoulou, J.W.Coding, H.Takakusa, K.Kikuchi, A.Perrakis, T.Nagano, W.H.Moolenaar
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 21155-21161
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phospahte.2005
- Author(s)
  L.A.van Metteren, P.Ruurs, E.Christodoulou, J.W.Goding, H.Takakusa, K.Kikuchi, A.Perrakis, T.Nagano, W.H.Moolenaar
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 21155-21161
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices.2005
- Author(s)
  K.Komatsu, K.Kikuchi, Y.Urano, H.Kojima, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 10197-10204
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and Zn^<-65(2+)> Uptake.2005
- Author(s)
  R.A.Colvin, P.Fontaine, D.Thomas, T.Hirano, T.Nagano, K.Kikuchi
- Journal Title
  
  Arch.Biochem.Biophys. 442
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+>in Hippocampal Slices2005
- Author(s)
  Kensuke Komatsu, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 10197-10204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications.2005
- Author(s)
  E.Kawabata, K.Kikuchi, Y.Urano, H.Kojima, A.Odani, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 818-819
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and Zn^<-65(2+)> Uptake.2005
- Author(s)
  R.A.Colvin, P.Fontaine, D.Thomas, T.Hirano, T.Nagano, K.Kikuchi
- Journal Title
  
  Arch.Biochem.Biophys. 442
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs2005
- Author(s)
  Sasaki, E., Kojima, H., Nishimatsu, H., Urano, Y., Kikuchi, K.., Hirata Y., Nagano. T.
- Journal Title
  
  Journal of the American Chemical Society 127
  
  Pages: 3684-3685
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices2005
- Author(s)
  Komatsu, K., Kikuchi, K., Kojima, H., Urano Y., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 127
  
  Pages: 10197-10204
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications.2005
- Author(s)
  E.Kawabata, K.Kikuchi, Y.Urano, H.Kojima, A.Odani, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 818-819
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications.2005
- Author(s)
  E.Kawabata, K.Kikuchi, Y.Urano, H.Kojima, A.Odani, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 818-819
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Design and Synthesis of Zinc-Selective chelators for Extracellular Applications.2005
- Author(s)
  E.Kawabata, K.Kikuchi, Y.Urano, H.Kojima, A.Odani, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 818-819
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and Zn^<-65(2+)> Uptake.2005
- Author(s)
  R.A.Colvin, P.Fontaine, D.Thomas, T.Hirano, T.Nagano, K.Kikuchi
- Journal Title
  
  Arch.Biochem.Biophys. 442
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs.2005
- Author(s)
  E.Sasaki, H.Kojima, H.Nishimatsu, Y.Urano, K.Kikuchi, Y.Hirata, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3684-3685
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices.2005
- Author(s)
  K.Komatsu, K.Kikuchi, Y.Urano, H.Kojima, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 10197-10204
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices.2005
- Author(s)
  K.Komatsu, K.Kikuchi, Y.Urano, H.Kojima, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 10197-10204
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs.2005
- Author(s)
  E.Sasaki, H.Kojima, H.Nishimatsu, Y.Urano, K.Kikuchi, Y.Hirata T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3684-3685
- Data Source
  KAKENHI-PROJECT-17035019
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs.2005
- Author(s)
  E.Sasaki, H.Kojima, H.Nishimatsu, Y.Urano, K.Kikuchi, Y.Hirata, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3684-3685
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phosphate.2005
- Author(s)
  L.A.van Meeteren, P.Ruurs, E.Christodoulou, J.W.Goding, H.Takakusa, K.Kikuchi, A.Perrakis, T.Nagano, W.H.Moolenaar
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 21155-21161
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs2005
- Author(s)
  Eita Sasaki, Hirotatsu Kojima, Hiroaki Nishimatsu, Yasuteru Urano, Kazuya Kikuchi, Yasunobu Hirata, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 3684-3685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs.2005
- Author(s)
  E.Sasaki, H.Kojima, H.Nishimatsu, Y.Urano, K.Kikuchi, Y.Hirata, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3684-3685
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>,Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices.2005
- Author(s)
  K.Komatsu, K.Kikuchi, Y.Urano, H.Kojima, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 10197-10204
- Data Source
  KAKENHI-PROJECT-17651119
[Journal Article] Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications2005
- Author(s)
  Kawabata, E., Kikuchi, K., Urano, Y., Kojima, H., Odani, A., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 127
  
  Pages: 818-819
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Evidence for pH Dependent Zn^<2+> Influx in K562 Erythroleukemia Cells : Studies Using ZnAF-2F Fluorescence and Zn^<-65(2+)> Uptake.2005
- Author(s)
  R.A.Colvin, P.Fontaine, D.Thomas, T.Hirano, T.Nagano, K.Kikuchi
- Journal Title
  
  Arch.Biochem.Biophys. 442
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-17048006
[Journal Article] Selective Zinc Sensor Molecules with Various Affinities for Zn^<2+>, Revealing Dynamics and Regional Distribution of Synaptically Released Zn^<2+> in Hippocampal Slices.2005
- Author(s)
  K.Komatsu, K.Kikuchi, Y.Urano, H.Kojima, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 10197-10204
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs.2005
- Author(s)
  E.Sasaki, H.Kojima, H.Nishimatsu, Y.Urano, K.Kikuchi, Y.Hirata, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3684-3685
- Data Source
  KAKENHI-PROJECT-17036012
[Journal Article] Zinc Sensing for Cellular Application2004
- Author(s)
  Kikuchi, K., Komatsu, K., Nagano, T.
- Journal Title
  
  Current Opinion in Chemical Biology 8
  
  Pages: 182-191
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Rational Design of Novel Photoinduced Electron Transfer Type Fluorescent Probes for Sodium Cation2004
- Author(s)
  Kenmoku, K., Urano, Y., Kanda, K., Kojima, H., Kikuchi, K., Nagano, T.
- Journal Title
  
  Tetrahedron 60
  
  Pages: 11067-11073
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-Specific Manner in the Rat Cerebellar Cortex2004
- Author(s)
  Daisuke 0kada, Chan-Choo Yap, Hirotatsu Kojima, Kazuya Kikuchi, Tetsuo Nagano
- Journal Title
  
  Neuroscience 125
  
  Pages: 461-472
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-Specific Manner the Rat Cerebellar Cortex2004
- Author(s)
  Okada, D., Yap, C., Kojima, H., Kikuchi, K., Nagano, T.
- Journal Title
  
  Neuroscience 125
  
  Pages: 461-472
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Modification of Intracellular Ca^<2+> Dynamics by Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptor Using Membrane-permeant Probes.2004
- Author(s)
  T.Yogo, K.Kikuchi, K.Hirose, M.Iino, T.Nagano
- Journal Title
  
  Chemistry & Biology 11
  
  Pages: 1053-1058
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Modification of Intracellular Ca^<2+> Dynamics by Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptor Using Membrane-permeant Probes.2004
- Author(s)
  T.Yogo, K.Kikuchi, K.Hirose, M.Iino, T.Nagano
- Journal Title
  
  Chemistry & Biology 11
  
  Pages: 1053-1058
- Data Source
  KAKENHI-PROJECT-16048206
[Journal Article] Recent Advances in Design of Small Molecule Based FRET Sensors for Cell Biology.2004
- Author(s)
  K.Kikuchi, H.Takakusa, T.Nagano
- Journal Title
  
  Trends Anal.Chem. 23
  
  Pages: 407-415
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Recent Advances in Design of Small Molecule Based FRET Sensors for Cell Biology.2004
- Author(s)
  K.Kikuchi, H.Takakusa, T.Nagano
- Journal Title
  
  Trends Anal.Chem. 23
  
  Pages: 407-415
- Data Source
  KAKENHI-PROJECT-16048206
[Journal Article] Zinc Sensing for Cellular Application2004
- Author(s)
  Kazuya Kikuchi, Kensuke Komatsu, Tetsuo Nagano
- Journal Title
  
  Current Opinion in Chemical Biology 8
  
  Pages: 182-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-specific Manner in the Rat Cerebellar Cortex.2004
- Author(s)
  D.Okada, C.C.Yap, H.Kojima, K.Kikuchi, T.Nagano
- Journal Title
  
  Neuroscience 125
  
  Pages: 461-472
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Zinc Sensing for Cellular Applications.2004
- Author(s)
  K.Kikuchi, K.Komatsu, T.Nagano
- Journal Title
  
  Curr.Opi.Chem.Biol. 8
  
  Pages: 182-191
- Data Source
  KAKENHI-PROJECT-16048206
[Journal Article] Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene Chromophore-Rational Design of Potentially Useful Bioimaging Fluorescence Probe-2004
- Author(s)
  Gabe, Y., Urano, Y., Kikuchi, K, Kojima, H., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 126
  
  Pages: 3357-3367
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Rational Principles for Modulating Fluorescence Properties of Fluorescein2004
- Author(s)
  Ueno, T., Urano, Y., Setsukinai, K., Takakusa, H., Kojima, H., Kikuchi, K., Ohkubo, K., Fukuzumi, K., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 126
  
  Pages: 14079-14085
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Zinc Sensing for Cellular Applications.2004
- Author(s)
  K.Kikuchi, K.Komatsu, T.Nagano
- Journal Title
  
  Curr.Opi.Chem.Biol. 8
  
  Pages: 182-191
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Rational Principles for Modulating Fluorescence Properties of Fluorescein2004
- Author(s)
  Tasuku Ueno, Yasuteru Urano, Ken-ichi Setsukinai, Hideo Takakusa, Hirotatsu Kojima, Kazuya Kikuchi, Kei Ohkubo, Shunichi Fukuzumi, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 126
  
  Pages: 14079-14085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Modification of Intracellular Ca^<2+>Dynamics by Laser Inactivation of Inositol 1,4,5-Triphosphate Receptor Using Membrane-Permeant Probes2004
- Author(s)
  Yogo, T., Kikuchi, K, Inoue, T., Hirose, K, Iino, M., Nagano, T
- Journal Title
  
  Chemistry & Biology 11
  
  Pages: 1053-1058
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Nonspecific Medium Effects versus Specific Group Positioning in the Antibody and Albumin Catalysis of the Base-Promoted Ring-Opening Reactions of Benzisoxazoles.2004
- Author(s)
  Y.Hu, K.N.Houk, K.Kikuchi, K.Hotta, D.Hilvert
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 8197-8205
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Rational Design of Novel Photoinduced Electron Transfer Type Fluorescent Probes for Sodium Cation2004
- Author(s)
  Suguru Kenmoku, Yasuteru Urano, Koujirou Kanda, Hirotatsu Kojima, Kazuya Kikuchi, Tetsuo Nagano
- Journal Title
  
  Tetrahedron 60
  
  Pages: 11067-11073
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Recent Advances in the Design of Small Molecule-Based FRET Sensors for Cell Biology2004
- Author(s)
  Kikuchi, K., Takakusa, H., Nagano, T.
- Journal Title
  
  Trends in Analytical Chemistry 23
  
  Pages: 407-415
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Modification of Intracellular Ca^<2+>Dynamics by Laser Inactivation of Inositol 1,4,5-Triphosphate Receptor Using Membrane-Permeant Probes2004
- Author(s)
  Takatoshi Yogo, Kazuya Kikuchi, Takanari Inoue, Kenzo Hirose, Masamitsu Tino, Tetsuo Nagano
- Journal Title
  
  Chemistry & Biology 11
  
  Pages: 1053-1058
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] A Novel Fluorescent Probe for Zinc Ion Based on BODIPY Chromophore2004
- Author(s)
  Koutaka, H., Kosuge, J., Fukasaku, N., Hirano, T., Kikuchi, K., Urano, Y., Kojima, H., Nagano, T.
- Journal Title
  
  Chemical & Pharmaceutical Bulletin 52
  
  Pages: 700-703
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Development of a Zinc Ion-Selective Luminescent Lanthanide Chemosensor for Biological Applications2004
- Author(s)
  Hanaoka, K., Kikuchi, K., Kojima, H., Urano, Y., Nagano, T.
- Journal Title
  
  Journal of the American Chemical Society 126
  
  Pages: 12470-12476
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] A Novel Fluorescent Probe for Zinc Ion Based on BODIPY Chromophore2004
- Author(s)
  Hitomi Koutaka, Jun-ichi Kosuge, Noboru Fukasaku, Tomoya Hirano, Kazuya Kikuchi, Yasuteru Urano, Hirotatsu Kojima, Tetsuo Nagano
- Journal Title
  
  Chem. Pharm. Bull 52
  
  Pages: 700-703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Development of a Zinc Ion-Selective Luminescent Lanthanide Chemosensor for Biological Applications2004
- Author(s)
  Kenjiro Hanaoka, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 126
  
  Pages: 12470-12476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Recent Advances in the Design of Small Molecule-Based FRET Sensors for Cell Biology2004
- Author(s)
  Kazuya Kikuchi, Hideo Takakusa, Tetsuo Nagano
- Journal Title
  
  Trends in Analytical Chemistry 23
  
  Pages: 407-415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Nonspecific Medium Effects versus Specific Group Positioning in the Antibody and Albumin Catalysis of the Base-Promoted Ring-Opening Reactions of Benzisoxazoles.2004
- Author(s)
  Y.Hu, K.N.Houk, K.Kikuchi, K.Hotta, D.Hilvert
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 8197-8205
- Data Source
  KAKENHI-PROJECT-16048206
[Journal Article] Development of a Zinc Ion-selective Luminescent Lanthanide Chemosensor for Biological Applications.2004
- Author(s)
  K.Hanaoka, K.Kikuchi, H.Kojima, Y.Urano, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 12470-12476
- Data Source
  KAKENHI-PROJECT-15681012
[Journal Article] Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-specific Manner in the Rat Cerebellar Cortex.2004
- Author(s)
  D.Okada, C.C.Yap, H.Kojima, K.Kikuchi, T.Nagano
- Journal Title
  
  Neuroscience 125
  
  Pages: 461-472
- Data Source
  KAKENHI-PROJECT-16048206
[Journal Article] Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene Chromophore -Rational Design of Potentially Useful Bioimaging Fluorescence Probe2004
- Author(s)
  Yu Gabe, Yasuteru Urano, Kazuya Kikuchi, Hirotatsu Kojima, Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc. 126
  
  Pages: 3357-3367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Journal Article] Development of a Zinc Ion-selective Luminescent Lanthanide Chemosensor for Biological Applications.2004
- Author(s)
  K.Hanaoka, K.Kikuchi, H.Kojima, Y.Urano, T.Nagano
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 12470-12476
- Data Source
  KAKENHI-PROJECT-16048206
[Patent] タンパク質間相互作用を可視化する方法2024
- Inventor(s)
  蓑島維文、Jiatong Li、菊地和也
- Industrial Property Rights Holder
  蓑島維文、Jiatong Li、菊地和也
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21H04706
[Patent] タンパク質間相互作用を可視化する方法2024
- Inventor(s)
  蓑島維文、Jiatong Li、菊地和也
- Industrial Property Rights Holder
  蓑島維文、Jiatong Li、菊地和也
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23KK0106
[Patent] タンパク質を蛍光標識する手法2023
- Inventor(s)
  蓑島維文、Reja Shahi Imam、飯嶋航平、菊地和也
- Industrial Property Rights Holder
  蓑島維文、Reja Shahi Imam、飯嶋航平、菊地和也
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H04706
[Patent] ケージド化合物から化合物を放出させる方法2021
- Inventor(s)
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Holder
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-022014
- Filing Date
  2021
- Data Source
  KAKENHI-PLANNED-17H06409
[Patent] ケージド化合物から化合物を放出させる方法2021
- Inventor(s)
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Holder
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-022014
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K22255
[Patent] ケージド化合物から化合物を放出させる方法2021
- Inventor(s)
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Holder
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-022014
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21H04706
[Patent] ケージド化合物から化合物を放出させる方法2021
- Inventor(s)
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Holder
  蓑島維文、橋本　龍、菊地和也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-022014
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H03935
[Patent] メチル化DNAを蛍光標識する方法2015
- Inventor(s)
  菊地和也、堀雄一郎、乙村法道
- Industrial Property Rights Holder
  菊地和也、堀雄一郎、乙村法道
- Industrial Property Rights Type
  特許
- Filing Date
  2015-08-01
- Data Source
  KAKENHI-PROJECT-25220207
[Patent] タンパク質を蛍光標識する方法2013
- Inventor(s)
  菊地和也,堀雄一郎,上野秀樹
- Industrial Property Rights Holder
  大阪大学
- Acquisition Date
  2013-06-28
- Overseas
- Data Source
  KAKENHI-PROJECT-20675004
[Patent] タンパク質を二段階標識する方法2009
- Inventor(s)
  菊地和也,堀雄一郎,上野秀樹
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-03-10
- Data Source
  KAKENHI-PROJECT-20675004
[Patent] タンパク質を蛍光標識する方法2009
- Inventor(s)
  菊地和也, 堀雄一郎, 上野秀樹
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-03-10
- Data Source
  KAKENHI-PROJECT-20675004
[Patent] 希土類発光プローブ2008
- Inventor(s)
  菊地和也,水上進,東内一博
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2008-03-11
- Data Source
  KAKENHI-PROJECT-20675004
[Patent] ホスホクマリン誘導体およびそれを含む蛍光プローブ2008
- Inventor(s)
  菊地和也,水上進,渡辺修司
- Industrial Property Rights Holder
  大阪大学,(財)大阪産業振興機構
- Filing Date
  2008-02-21
- Overseas
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Development of 19F Magnetic Resonance Imaging Probe for in vivo Sensing Biomarkers2024
- Author(s)
  Kazuya Kikuchi
- Organizer
  第11回武田科学振興財団薬科学シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106
[Presentation] Development of 19F Magnetic Resonance Imaging Probe for in vivo Sensing Biomarkers2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  16th International Symposium on Applied Bioinorganic Chemistry (ISABC16)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] Development of 19F Magnetic Resonance Imaging Probe for in vivo Sensing Biomarkers2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICBIC-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] 天然物が織り成す化合物潜在空間が拓く生物活性分子デザイン2023
- Author(s)
  菊地和也
- Organizer
  「AIと有機合成化学」第１１回勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] 天然物が織り成す化合物潜在空間が拓く生物活性分子デザイン2023
- Author(s)
  菊地和也
- Organizer
  「AIと有機合成化学」第１１回勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0106
[Presentation] Chemical Probes with Tunable Fluorescence Properties2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  FASEB Science Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106
[Presentation] Development of 19F Magnetic Resonance Imaging Probe for in vivo Sensing Biomarkers2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  16th International Symposium on Applied Bioinorganic Chemistry (ISABC16)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106
[Presentation] Chemical Probes with Tunable Fluorescence Properties2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  FASEB Science Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] Development of 19F Magnetic Resonance Imaging Probe for in vivo Sensing Biomarkers2023
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICBIC-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0106
[Presentation] Nano-particle Based 19F MRI Contrast Agent with Tunable Chemical Switches2022
- Author(s)
  Kazuya Kikuchi
- Organizer
  The Future of Molecular MR 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] Nano-particle based 19F MRI contrast agent with tunable chemical switches2021
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] Nano-particle based 19F MRI contrast agent with tunable chemical switches2021
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04706
[Presentation] Nano-particle based 19F MRI contrast agent with tunable chemical switches2021
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] Nano-particle based 19F MRI contrast agent with tunable chemical switches2021
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] in vivo Imaging Probes to Clarify Cellular and Molecular Functions2020
- Author(s)
  Kazuya Kikuchi
- Organizer
  RSC Tokyo International Conferences 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] in vivo Imaging Probes to Clarify Cellular and Molecular Functions2020
- Author(s)
  Kazuya Kikuchi
- Organizer
  RSC Tokyo International Conferences 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] イメージングプローブのデザイン・合成によるケミカルバイオロジー研究2019
- Author(s)
  菊地　和也
- Organizer
  第１９回日本蛋白質科学会年会　第７１回日本細胞生物学会大会　合同年次学会
- Invited
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  ICBIC-19, International Conference on Biological Inorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] 化学プローブによって明らかになった生命現象2019
- Author(s)
  菊地和也
- Organizer
  日本分析化学会第６８年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] In vivo Multicolor Imaging with Fluorescent Probes Revealed Dynamics and Function of Osteoclast Proton Pumps2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  16th International, Methods & Applications of Fluorescence (Roger Y Tsien Memorial Symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] In vivo Multicolor Imaging with Fluorescent Probes Revealed Dynamics and Function of Osteoclast Proton Pumps2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  16th International, Methods & Applications of Fluorescence (Roger Y Tsien Memorial Symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] New Biological Findings which were Revealed by Designed Fluorescent Probes2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  Chemical Biology & Physiology Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  ICBIC-19, International Conference on Biological Inorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] イメージングプローブのデザイン・合成によるケミカルバイオロジー研究2019
- Author(s)
  菊地　和也
- Organizer
  第１９回日本蛋白質科学会年会　第７１回日本細胞生物学会大会　合同年次学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2019
- Author(s)
  Kazuya Kikuchi
- Organizer
  The Future of Molecular MR: A Cellular and Molecular Imaging Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  The Future of Molecular MR: A Cellular and Molecular Imaging Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  The Future of Molecular MR: A Cellular and Molecular Imaging Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] in vivo Chemical Probes for MRI and Fluorescence Imaging2019
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICBIC-19, International Conference on Biological Inorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] In vivo Multicolor Imaging with Fluorescent Probes Revealed Dynamics and Function of Osteoclast Proton Pumps2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  16th International, Methods & Applications of Fluorescence (Roger Y Tsien Memorial Symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] New Biological Findings which were Revealed by Designed Fluorescent Probes2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  Chemical Biology & Physiology Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] New Biological Findings which were Revealed by Designed Fluorescent Probes2019
- Author(s)
  Kazuya Kikuchi
- Organizer
  Chemical Biology & Physiology Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] In vivo Multicolor Imaging with Fluorescent Probes Revealed Dynamics and Function of Osteoclast Proton Pumps2019
- Author(s)
  Kazuya Kikuchi
- Organizer
  16th International, Methods & Applications of Fluorescence (Roger Y Tsien Memorial Symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] イメージングプローブのデザイン・合成によるケミカルバイオロジー研究2019
- Author(s)
  菊地和也
- Organizer
  第１９回日本蛋白質科学会年会　第７１回日本細胞生物学会大会　合同年次学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] New Biological Findings which were Revealed by Designed Fluorescent Probes2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  Chemical Biology & Physiology Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  ICBIC-19, International Conference on Biological Inorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] イメージングプローブのデザイン・合成によるケミカルバイオロジー研究2019
- Author(s)
  菊地　和也
- Organizer
  第１９回日本蛋白質科学会年会　第７１回日本細胞生物学会大会　合同年次学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22255
[Presentation] Development of PYP-tag far-red fluorogenic probes for intracellular protein imaging2019
- Author(s)
  Reja Imam Shahi、Hori Yuichiro、Kikuchi Kazuya
- Organizer
  The 99th Annual Meeting of Chemical Society of Japan
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2019
- Author(s)
  Kikuchi Kazuya
- Organizer
  The Future of Molecular MR: A Cellular and Molecular Imaging Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] New Biological Findings Which Were Revealed by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  A3 Meeting for Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] New Biological Findings Which Were Clarified by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  MSMLG 2018, 6th International Conference on Molecular Sensors and Molecular Logic Gates
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] Design and Development of PYP-tag Coumarin Ligands with Halomethyl Ketone Moieties for Fluorogenic Protein Labeling2018
- Author(s)
  Kumar Naresh、Hori Yuichiro、Kikuchi Kazuya
- Organizer
  The 98th Annual Meeting of Chemical Society of Japan
- Data Source
  KAKENHI-PROJECT-16F16331
[Presentation] New Biological Findings Which Were Clarified by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  MSMLG 2018, 6th International Conference on Molecular Sensors and Molecular Logic Gates
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16331
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  Imaging in 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  The 9th Asian Biological Inorganic Chemistry Conference (AsBIC IX)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18116
[Presentation] New Biological Findings Which Were Clarified by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  MSMLG 2018, 6th International Conference on Molecular Sensors and Molecular Logic Gates
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  Imaging in 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  Imaging in 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  Imaging in 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] Development of Multifunctional 19F MRI Contrast Agents Based on Fluorine-encapsulated Silica Nanoparticle2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  Imaging in 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16331
[Presentation] New Biological Findings Which Were Clarified by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  MSMLG 2018, 6th International Conference on Molecular Sensors and Molecular Logic Gates
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  The 9th Asian Biological Inorganic Chemistry Conference (AsBIC IX)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16331
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  The 9th Asian Biological Inorganic Chemistry Conference (AsBIC IX)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] New Biological Findings Which Were Revealed by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  A3 Meeting for Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Design and development of PYP-tag coumarin ligands with halomethyl ketone moieties for fluorogenic protein labeling2018
- Author(s)
  Naresh Kumar, Yuichiro Hori, Kazuya Kikuchi
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16F16331
[Presentation] New Biological Findings Which Were Clarified by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  MSMLG 2018, 6th International Conference on Molecular Sensors and Molecular Logic Gates
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] New Biological Findings Which Were Revealed by Designed Chemical Probes2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  A3 Meeting for Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] In Vivo Chemical Probes for MRI and Fluorescence Imaging2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  The 9th Asian Biological Inorganic Chemistry Conference (AsBIC IX)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03935
[Presentation] In vivo Chemical Probes for MRI and Fluorescence Imaging2018
- Author(s)
  Kikuchi Kazuya
- Organizer
  The 9th Asian Biological Inorganic Chemistry Conference (AsBIC IX)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06409
[Presentation] 有機蛍光色素の光安定性に及ぼす希土類イオン添加の効果2017
- Author(s)
  井元琢真, 水上進, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  慶應大学（横浜）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K13102
[Presentation] タンパク質ラベル化型Mg 2+プローブによるアポトーシス時の細胞内Mg2+動態イメージング2017
- Author(s)
  松井勇輔, 水上進, 船戸洋佑, 今村博臣, 三木裕明, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  慶應大学（横浜）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2017
- Author(s)
  Kikuchi Kazuya
- Organizer
  14th International Symposium on Applied Bioinorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] 有機蛍光色素の光安定性に及ぼす希土類イオン添加の効果2017
- Author(s)
  井元琢真, 水上進, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  慶應大学（横浜）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] タンパク質ラベル化プローブを用いた細胞内タンパク質挙動の1 分子解析2016
- Author(s)
  鈴木駿佑, 佐藤亮太, 小塚淳, 熊谷雄太郎, 水上進, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学（京都府宇治市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  K. Kikuchi
- Organizer
  MSMLG 2016, 5th International Conference on Molecular Sensors and Molecular Logic Gates
- Place of Presentation
  Bath, UK
- Year and Date
  2016-07-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13099
[Presentation] Development of Activatable 19F MRI Nanoprobes Using Perfluorocarbon Encapsulated in Silica Nanoparticle2016
- Author(s)
  Kazuki Akazawa, Fuminori Sugihara, Yoshichika Yoshioka, Shin Mizukami, Kazuya Kikuchi
- Organizer
  World molecular imaging congress 2016
- Place of Presentation
  ニューヨーク（USA）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Strategy to improve photostability of fluorescent dyes by using lanthanide ion2016
- Author(s)
  Takuma Imoto, Shin Mizukami, Kazuya Kikuchi
- Organizer
  Labeling & Nanoscopy 2016
- Place of Presentation
  ハイデルベルク（ドイツ）
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  K. Kikuchi
- Organizer
  MSMLG 2016, 5th International Conference on Molecular Sensors and Molecular Logic Gates
- Place of Presentation
  Bath, UK
- Year and Date
  2016-07-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00768
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  The 8th Asian Biological Inorganic Chemistry Conference (AsBIC VIII)
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  ICPP-9, 9th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Nanjing, China
- Year and Date
  2016-07-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] 高感度19F MRI 造影剤を用いたマルチスペクトルイメージング2016
- Author(s)
  有薗賢志, 杉原文徳, 赤澤一樹, 吉岡芳親, 向井大陽, 水上進, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学（京都府宇治市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] 標的タンパク質周辺の酸性環境を可視化するpH応答性蛍光プローブの開発2016
- Author(s)
  鈴木駿佑, 山縣勇介, 水上進, 菊地和也
- Organizer
  第10回バイオ関連化学合同シンポジウム
- Place of Presentation
  金沢音楽堂（金沢）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  K. Kikuchi
- Organizer
  MSMLG 2016, 5th International Conference on Molecular Sensors and Molecular Logic Gates
- Place of Presentation
  Bath, UK
- Year and Date
  2016-07-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity2016
- Author(s)
  K. Kikuchi
- Organizer
  MSMLG 2016, 5th International Conference on Molecular Sensors and Molecular Logic Gates
- Place of Presentation
  Bath, UK
- Year and Date
  2016-07-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] タンパク質ラベル化型Mg2+プローブによるアポトーシス時の細胞内Mg2+動態イメージング2016
- Author(s)
  松井勇輔, 水上進, 船戸洋佑, 今村博臣, 三木裕明, 菊地和也
- Organizer
  第10回バイオ関連化学合同シンポジウム
- Place of Presentation
  金沢音楽堂（金沢）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  ICPP-9, 9th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Nanjing, China
- Year and Date
  2016-07-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] タンパク質ラベル化型Mg2+プローブによる細胞内局所のMg2+イメージング2016
- Author(s)
  松井勇輔, 水上進, 船戸洋佑, 三木裕明, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学（京都府宇治市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  The 8th Asian Biological Inorganic Chemistry Conference (AsBIC VIII)
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13099
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  The 8th Asian Biological Inorganic Chemistry Conference (AsBIC VIII)
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  ICPP-9, 9th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Nanjing, China
- Year and Date
  2016-07-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13099
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  ICPP-9, 9th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Nanjing, China
- Year and Date
  2016-07-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00768
[Presentation] Strategy to improve photostability of fluorescent dyes by using lanthanide ion2016
- Author(s)
  Takuma Imoto, Shin Mizukami, Kazuya Kikuchi
- Organizer
  Labeling & Nanoscopy 2016
- Place of Presentation
  ハイデルベルク（ドイツ）
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13102
[Presentation] フォトクロミック分子を用いた人工βターン構造の光制御2016
- Author(s)
  樫部順美, 水上進, 菊地和也
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学（京都府宇治市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Real-time Intravital Imaging of pH Variation Associated with Osteoclast Activity Using BODIPY Based Two Photon Excitation Probes2016
- Author(s)
  K. Kikuchi
- Organizer
  The 8th Asian Biological Inorganic Chemistry Conference (AsBIC VIII)
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00768
[Presentation] 細胞内局所のMg2+動態を可視化するための蛍光プローブの開発2015
- Author(s)
  松井勇輔、水上進、船戸洋佑、三木裕明、菊地和也
- Organizer
  日本分子イメージング学会第10回学術集会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] タンパク質ラベル化プローブの開発および多色1分子イメージングへの応用2015
- Author(s)
  佐藤亮太、吉村彰真、小塚淳、熊谷雄太郎、水上進、菊地和也
- Organizer
  第24回日本バイオイメージング学会学術集会
- Place of Presentation
  東京理科大学（東京都葛飾区）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Development of activatable 19F MRI contrast agents based on paramagnetic relaxation enhancement2015
- Author(s)
  Kazuki Akazawa, Fuminori Sugihara, Yoshichika Yoshioka, Shin Mizukami, Kazuya Kikuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  13th International Symposium on Applied Bioinorganic Chemistry (ISABC13)
- Place of Presentation
  Galway, Ireland
- Year and Date
  2015-06-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102529
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  K. Kikuchi
- Organizer
  13th International Symposium on Applied Bioinorganic Chemistry (ISABC13)
- Place of Presentation
  Galway, Ireland
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] 特定のタンパク質近傍のpH環境の可視化を目指した蛍光プローブの開発2015
- Author(s)
  鈴木駿佑、山形勇介、水上進、菊地和也
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学（仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Highly Sensitive 19F MRI Probes with Tunable Chemical Switches Using Metal Complexes2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICBIC-17, International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Beijing, China
- Year and Date
  2015-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102529
[Presentation] 常磁性緩和促進効果に基づいた刺激応答性19F MRI造影剤の開発2015
- Author(s)
  赤沢一樹、杉原文徳、中村竜也、吉岡芳親、水上進、菊地和也
- Organizer
  日本分子イメージング学会第10回学術集会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] 刺激応答性19F MRIナノプローブの開発2015
- Author(s)
  石田健一郎、赤澤一樹、杉原文徳、吉岡芳親、水上進、菊地和也
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学（仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  13th International Symposium on Applied Bioinorganic Chemistry (ISABC13)
- Place of Presentation
  Galway, Ireland
- Year and Date
  2015-06-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  K. Kikuchi
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu HI, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Development of Protein Labeling Probes and Application to Multicolor Single-Molecule Imaging2015
- Author(s)
  Ryota Sato, Akimasa Yoshimura, Jun Kozuka, Yutaro Kumagai, Shin Mizukami, Kazuya Kikuchi
- Organizer
  ECBS & ICBS Joint Meeting
- Place of Presentation
  Berlin (Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102529
[Presentation] Development of Protein-Tag-Based Research Tools in Live Cell Imaging2015
- Author(s)
  Shin Mizukami, Kazuya Kikuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Stimulus-Responsive Control of Peptide Structure and its Functions Directed toward Molecular Robotics2015
- Author(s)
  水上進、樫部順美、菊地和也
- Organizer
  CBI学会2015年大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Development of Fluorescent Probe for Visualizing Local Mg2+ Dynamics in Living Cells2015
- Author(s)
  Yusuke Matsui, Shin Mizukami, Yosuke Funato, Hiroaki Miki, Kazuya Kikuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Highly Sensitive 19F MRI Probes with Tunable Chemical Switches Using Metal Complexes2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICBIC-17, International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Beijing, China
- Year and Date
  2015-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] Improvement of photostability of fluorescent dyes by using lanthanide complex2015
- Author(s)
  Takuma Imoto, Shin Mizukami, Kazuya Kikuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03120
[Presentation] Highly Sensitive 19F MRI Probes with Tunable Chemical Switches Using Metal Complexes2015
- Author(s)
  K. Kikuchi
- Organizer
  ICBIC-17, International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Beijing, China
- Year and Date
  2015-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12754
[Presentation] Development of Multifunctional 19F MRI Contrast Agents with Fluorine-encapsulated Silica Nanoparticle2015
- Author(s)
  Kazuya Kikuchi
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Design, Synthesis and Biological Application of in Vivo Imaging Probes with Tunable Chemical Switches2013
- Author(s)
  Kazuya Kikuchi
- Organizer
  ICMAT 2013
- Place of Presentation
  Singapore
- Invited
- Data Source
  KAKENHI-PROJECT-25620133
[Presentation] Fluorogenic Intracellular Protein Labeling Using Synthetic Chemical Probes for Imaging Quick Responses of target Localization and Degradation2013
- Author(s)
  K. Kikuchi
- Organizer
  The 27^<th> Annual Symposium of the Protein Society
- Place of Presentation
  Boston MA, U.S.A
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of Molecular Imaging Probes with Tunable Chemical Switches2013
- Author(s)
  Kazuya Kikuchi
- Organizer
  AIMECS 2013
- Place of Presentation
  Taiwan
- Invited
- Data Source
  KAKENHI-PROJECT-25620133
[Presentation] Design Strategy of Chemical Probes for in vivo Imaging2013
- Author(s)
  Kazuya Kikuchi
- Organizer
  Advanced Practical Course in Chemical Biology
- Place of Presentation
  Germany
- Invited
- Data Source
  KAKENHI-PUBLICLY-24108724
[Presentation] Intracellular Protein Labeling for Imaging Protein Degradation2013
- Author(s)
  Kazuya Kikuchi
- Organizer
  Asian Chemical Biology Initiative, 2013 Bangkok Meeting
- Place of Presentation
  Thailand
- Invited
- Data Source
  KAKENHI-PUBLICLY-24108724
[Presentation] Design, Synthesis and Biological Application of Molecular Imaging Probes with Tunable Chemical Switches2013
- Author(s)
  Kazuya Kikuchi
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  Singapore
- Invited
- Data Source
  KAKENHI-PUBLICLY-24108724
[Presentation] Design, Synthesis and Biological Application of Molecular Imaging Probes with Tunable Chemical Switches2012
- Author(s)
  Kazuya Kikuchi
- Organizer
  The 3^<rd> International Conference on Molecular Sensors & Logic Gates (MSMLG)
- Place of Presentation
  Korea University, Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] 分子イメージングプローブの設計戦略2012
- Author(s)
  菊地和也
- Organizer
  理化学研究所ケミカルバイオロジー講演会
- Place of Presentation
  理化学研究所, 和光市
- Year and Date
  2012-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] 生命現象を可視化する分子プローブの開発戦略2012
- Author(s)
  菊地和也
- Organizer
  平成24年度春季有機合成化学協会講習会
- Place of Presentation
  日本薬学会館, 東京都渋谷区
- Invited
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] 分子プローブのデザイン・合成による細胞内機能イメージング2012
- Author(s)
  菊地和也
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市、福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of in vivo Imaging Probes with Tunable Chemical Switches2011
- Author(s)
  Kikuchi Kazuya
- Organizer
  International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Vancouver (Canada)(招待講演)
- Year and Date
  2011-08-07
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of in Vivo Imaging Probes with Tunable Chemical Switches2011
- Author(s)
  K. Kikuchi
- Organizer
  Plenary Lecture, ICBIC-15, International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Fluorescent Sensor Molecules with Tunable Fluorescence Switches for Cellular Imaging2011
- Author(s)
  K. Kikuchi
- Organizer
  European Science Foundation Workshop, "Probes for Lipid Systems Biology"
- Place of Presentation
  Menaggio, Italy
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of in Vivo Imaging Probes with Tunable Chemical Switches2011
- Author(s)
  K. Kikuchi
- Organizer
  CAS 11 : Catalysis and Sensing for Health
- Place of Presentation
  Bath, United Kingdom
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of in Vivo Imaging Probes with Tunable Chemical Switches2010
- Author(s)
  K.Kikuchi
- Organizer
  EMBL Conference Series-Chemical Biology 2010
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Chemical Probes for in Vivo Molecular Imaging2010
- Author(s)
  K.Kikuchi
- Organizer
  Pacifichem 2010
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis and Biological Application of in Vivo Imaging Probes with Tunable Chemical Switches2010
- Author(s)
  K. Kikuchi
- Organizer
  EMBL Conference Series - Chemical Biology 2010
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Development of Imaging Probes with Tunable Switches for Biological Applications2009
- Author(s)
  K.Kikuchi
- Organizer
  The 238^<th> ACS National Meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2009-08-19
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Design, Synthesis of MRI Probes for in Vivo Imaging2009
- Author(s)
  K.Kikuchi
- Organizer
  2^<nd> Asian Conference on Coordination Chemistry
- Place of Presentation
  Nanjing, China
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] Development of Imaging Probes with Tunable Switches for Biological Applications2009
- Author(s)
  K. Kikuchi
- Organizer
  The 238^<th> ACS National Meeting, American Chemical Society
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-20675004
[Presentation] 遺伝子発現を検出可能な新規機能性MRIプローブの開発2007
- Author(s)
  花岡健二郎、菊地和也、長野哲雄
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] RATIONAL DESIGN OF LONG-LIVED LUMINESCENCE PROBES USING LANTHANIDE COMPLEXES2006
- Author(s)
  Takuya Terai, Yasuteru Urano, Kazuya Kikuchi, Tetsuo Nagano
- Organizer
  InternationalConference on f-elements
- Place of Presentation
  Wroclaw
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] 酵素反応を利用したタンパク質ラベル化プローブの開発と応用2006
- Author(s)
  小松徹、菊地和也、長野哲雄
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] 光共鳴エネルギー移動(FRET)型プローブを用いた選択的タンパク質ラベル化2005
- Author(s)
  小松徹、菊地和也、長野哲雄
- Organizer
  日本分析化学会第54年会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] 酵素反応により蛍光強度が変化するランタノイド錯体の開発2005
- Author(s)
  寺井琢也、菊地和也、長野哲雄
- Organizer
  第15回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] プロテアーゼ活性を定量する長寿命蛍光プローブの開発2005
- Author(s)
  寺井琢也、菊地和也、長野哲雄
- Organizer
  第24回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] 酵素反応により蛍光強度が変化するランタノイド錯体の開発2005
- Author(s)
  寺井琢也、菊地和也、長野哲雄
- Organizer
  錯体化学討論会
- Place of Presentation
  新潟
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370071
[Presentation] Intracellular Protein Labeling by Functional Probes with Tunable Chemical Switches
- Author(s)
  Kazuya Kikuchi
- Organizer
  Labeling and Nanoscopy
- Place of Presentation
  Heidelberg, Gemany
- Year and Date
  2014-09-24 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25220207
[Presentation] Intracellular Protein Labeling by Functional Probes with Tunable Chemical Switches
- Author(s)
  Kazuya Kikuchi
- Organizer
  Labeling and Nanoscopy
- Place of Presentation
  Heidelberg, Gemany
- Year and Date
  2014-09-24 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25620133
[Presentation] Design, Synthesis and Biological Application of Molecular Imaging Probes with Tunable Chemical Switches
- Author(s)
  Kazuya Kikuchi
- Organizer
  The 3rd International Conference on Molecular Sensors & Logic Gates (MSMLG)
- Place of Presentation
  Korea
- Invited
- Data Source
  KAKENHI-PUBLICLY-24108724
[Presentation] Intracellular Protein Labeling by Functional Probes with Tunable Chemical Switches
- Author(s)
  Kazuya Kikuchi
- Organizer
  Labeling and Nanoscopy
- Place of Presentation
  German Cancer Research Center (Gemany)
- Year and Date
  2014-09-24 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102529

1. MIZUKAMI Shin (30420433)

# of Collaborated Projects: 11 results

# of Collaborated Products: 37 results
2. 堀雄一郎 (00444563)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
3. URANO Yasuteru (20292956)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
4. HIGUCHI Tsunehiko (50173159)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NAGANO Tetsuo (20111552)

# of Collaborated Projects: 3 results

# of Collaborated Products: 47 results
6. 蓑島維文 (20600844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
7. HIRATA Yasunobu (70167609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 上田実 (60265931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 榊原康文 (10287427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. IMOTO TAKUMA

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. NAGAI Shin-ichi (40080212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UEDA Taisei (50080198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOJIMA Hirotatsu (70345255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
14. Kakeya Hideaki (00270596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松永茂樹 (60183951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 西尾和人 (10208134)

# of Collaborated Projects: 1 results

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17. 入江一浩 (00168535)

# of Collaborated Projects: 1 results

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18. 村田道雄 (40183652)

# of Collaborated Projects: 1 results

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19. 上杉志成 (10402926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. BOONE CHARLES (70601342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 長田裕之 (80160836)

# of Collaborated Projects: 1 results

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22. 河岸洋和 (70183283)

# of Collaborated Projects: 1 results

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23. 松森信明 (50314357)

# of Collaborated Projects: 1 results

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24. 野村尚生 (90597840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 伊藤寛晃 (20758205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 丹羽節 (30584396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 荒井緑 (40373261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大森建 (50282819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 大上雅史 (50743209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 鎌田真由美 (70749077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 吉田稔 (80191617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 山本智也 (30837886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. SUGIHARA Fuminori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. SHIMADA Noriaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. MATSUI YUSUKE

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
36. SATO RYOTA

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
37. AKAZAWA KAZUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
38. SUZUKI SHUNSUKE

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
39. KUMAR NARESH

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
40. REJA SHAHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
41. NISHIURA Miyako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. OTOMURA Norimichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. NISHIDA Ayuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. UMENO Maho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. TOCHIO HIDEHITO

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. DHARA Koushik

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
47. 小塚淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 菊田順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 三木裕明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 松下尚嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
51. 吉岡芳親

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 井端啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 松井敏高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 大西秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIKUCHI Kazuya 菊地 和也

Research Projects

Research Products

Co-Researchers

化学プローブのデザイン・合成が拓くin vivoイメージングPrincipal Investigator

Principal Investigator

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潜在空間を構成・検証する生物活性の時空間定量計測手法開発・応用Principal Investigator

Principal Investigator

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Latent Chemical Space Based on Diverse Natural Products for Bio-active Molecular DesignArea Organizer

Area Organizer

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天然物が織り成す化合物潜在空間が拓く生物活性分子デザインPrincipal Investigator

Principal Investigator

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Super-resolution imaging probe using novel chemical switchPrincipal Investigator

Principal Investigator

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Development of functional fluorescent probe for imaging osteocyte function and 4D nucleomicsPrincipal Investigator

Principal Investigator

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Fluorescent super-resolution imaging probe using novel chemical switching mechanismPrincipal Investigator

Principal Investigator

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Analysis of membrane protein dynamics with chemical approachesPrincipal Investigator

Principal Investigator

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がん細胞転移を可視化するシステインプロテアーゼ蛍光プローブPrincipal Investigator

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Understanding of chemical communications and higher-order functional evaluation of bioactive ligands by spatiotemporal analysisPrincipal Investigator

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Frontiers in Chemical Communications

Principal Investigator

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Designed Chemical Probes for Clarification of Biological Function of Target MoleculesPrincipal Investigator

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Fluorescence screening and imaging by chemical probes for detecting histone deacetylases/demethylases activityPrincipal Investigator

Principal Investigator

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KIKUCHI Kazuya 菊地和也