SAKAGUCHI Masakiyo 阪口政清

… Alternative Names

坂口正清サカグチマサキヨ

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Researcher Number	70379840
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学域, 教授 2018 – 2023: 岡山大学, 医歯薬学総合研究科, 教授 2017: 岡山大学, 大学院医薬学総合研究科細胞生物学, 准教授 2016 – 2017: 岡山大学, 医歯薬学総合研究科, 准教授 2011 – 2016: 岡山大学, 医歯(薬)学総合研究科, 准教授 … More 2015: 岡山大学, 大学院医歯薬総合研究科, 准教授 2014: 岡山大学, 医歯薬学総合研究科, 准教授 2008 – 2013: 岡山大学, 大学院・医歯薬学総合研究科, 准教授 2008: 岡山大学, 医歯薬学総合研究科, 准教授 2007: Okayama University, Department of Cell Biology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Research Associate 2006: 岡山大学, 大学院・医歯薬学総合研究科, 助手 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 助手 2004: Okayama University, Graduate School of Medicine and Dentistory Department of Cell Biology, Research Associate (2004), 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 50010:Tumor biology-related / Biological Sciences / Tumor immunology / Pathological medical chemistry / General physiology Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Respiratory surgery / Urology … More / Biological Sciences / Basic Section 50010:Tumor biology-related / Basic Section 48040:Medical biochemistry-related / Dermatology / Experimental pathology / Digestive surgery / Basic Section 53050:Dermatology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 48030:Pharmacology-related / Basic Section 49030:Experimental pathology-related / Basic Section 53020:Cardiology-related / Human pathology / General surgery / Cardiovascular medicine / General medical chemistry / Dermatology / Clinical oncology Less
Keywords	Principal Investigator 転移 / がん / S100A8/A9 / 炎症 / S100A8/A9受容体 / 受容体 / 阻害作用 / HRG / S100タンパク質 / シグナル伝達 … More / がん転移抑制タンパク質 / S100A8/A9中和抗 / H R G / 脳転移 / 中和抗体 / 浸潤 / 細胞 / 癌 / S100受容体 / 腫瘍免疫 / 膜タンパク質 / 抗体 / がん幹細胞 / RAGE / 多機能受容体 / イメージング / ヒト表皮角化細胞 / KLF16 / Sp1 / NFAT / Smad / TGFβ / Ca / アラキドン酸 / 増殖 / 表皮角化細胞 / Phospholipase A2 / Annexin I / A11 / S100C … More Except Principal Investigator REIC / 癌 / 肺癌 / Dkk-3 / がん / S100 / REIC/Dkk-3 / 膵癌 / S100A8/A9 / 転移 / 膵がん / Wnt / 外科 / HER2 / 核内受容体 / NASH / 遺伝子治療 / がん遺伝子治療 / 薬剤耐性 / RAGE / A11 / 治療 / 抗体 / 虚血再灌流障害 / 肺移植 / 血管内皮細胞 / HMGB1 / 走化性 / パーキンソン病 / 軸索変性 / ミトコンドリア / SARM1 / 抗体医薬品 / がん転移 / S100A9 / ERBB2 / 脂肪肝 / 脂肪酸 / S100蛋白 / 血小板由来増殖因子 / 細胞増殖 / 肺動脈平滑筋細胞 / 終末糖化産物受容体 / 肺高血圧症 / Hornerin / Ca / 皮膚 / 遺伝子 / HNF4α / 炎症 / がん抑制遺伝子 / DKK3 / 増殖制御 / S100C / 乾癬 / 増殖抑制 / TGFβ / マトリセルラー蛋白 / がん関連線維芽細胞 / マトリセルラータンパク質 / がん微小環境 / 非小細胞肺がん / 免疫細胞 / ドラッグデリバリー / 標的分子 / TPL2 / MCAM / アトピー性皮膚炎 / NAD / 低分子医薬 / がん幹細胞性 / 上皮間葉系移行 / SPFED2 / 低分子医療 / Spred2 / 炎症とがん / シグナル伝達・抑制 / オートファジー / ERK-MAPK / SPRED2 / 微小腫瘍環境 / がん肝細胞性 / 上皮間葉移行 / 内因性抑制因子 / シグナル伝達 / 診断 / 抗体医薬 / 制がん医療 / ホーミングペプチド / レセプター / 標的化 / バイオマーカー / HMGB１ / 抗S100A8/A9中和抗体 / S100A8 / 肺線維化 / ダメージ関連分子パターン / 抗HMGB1抗体 / サイトカイン類 / トランスロケーション / 腫瘍幹細胞マーカー / DCLK1 / 悪性胸膜中皮腫 / HER異常 / 胃がん / 乳がん / 肺がん / HER2異常 / リンパ組織 / S100タンパク質 / 活性酸素 / リンパ向性転移 / マイクロアレイ / 細胞動態 / S100 protein / リンパ内皮細胞 / 癌転移 / miRNA / 線維化 / 繊維化 / ミトコンドリア呼吸 / リン酸化 / metastasis / cancer / inflammation / antibody / 血管リモデリング / ナノ粒子 / RAGE-aptamer / 肺動脈性肺高血圧症 / モノクロタリン誘発性肺高血圧症 / DNA-aptamer / S100A8/A9蛋白 / 転移抑制物質 / Emmprin / 転移モデル / S100A8/9 / メラノーマ / 抗PD-1抗体 / メトホルミン / 病理学 / 浸潤 / PODXL1 / TRA-1-60 / サイトケラチン19 / 癌関連遺伝子 / Lung cancer / p53 / BTB/POZ / MYNN / 応用動物 / マウスモデル / 非アルコール性脂肪性肝炎 / 次世代シーケンサー / EGFR / 分子標的治療薬 / 非小細胞肺癌 / PDX / EMT / 次世代シークエンサー / 分子バーコード / 分子標的薬 / TIRAP / 肺高血圧 / 右室肥大 / 右室収縮期圧 / drug delivery system / ナノメディシン / Skin / Tumor suppressor gene / liver fibrosis / acute liver failure / transplantation / hepatocytes / a bone marrow-derived clonal mesenchymal stem cell / 肝線維症 / 急性肝不全 / 移植 / 肝細胞 / 骨髄間葉系幹細胞クローン / stem cells / keratinization / differentiation / growth regulation / skin / 組織構築 / calmin / 骨髄 / Profilaggrin / 増殖 / profilaggrin / hornerin / 幹細胞 / 角化 / 分化 / 臨床 / バイオテクノロジー / 癌増殖抑制 / チロシンキナーゼ阻害剤 / 遺伝子変異 / PPAR / PPARα / 組織幹細胞 / がん幹細胞 / TNF-α / 皮膚組織 / 腸管上皮組織 / アデノウイルス / 前立腺癌 / ＲＥＩＣ／Ｄｋｋ３ / 細胞傷害性Tリンパ球 / 骨髄系免疫制御細胞 / REIC/Dkk3 / 骨髄系免疫抑制細胞 / 癌ワクチン / Peritoneal Dissemination / Scirrhous Gastric Carcinoma / Gene Therapy / 癌化 / 前立腺 / Bip/GRP78 / 前立腺分化 / GRP78 / BiP / Akt / Ras-GTP / Ras / 不死化関連遺伝子 / 樹状細胞 / Id / Bip / 免疫 / NK細胞 / IL-7 / Dkk / HSP70 / Dkk3 / P-glycoprotein / JNK / ストレス応答分子 / 遺伝子治療学 / 腫瘍学 / Annexin A1 / ヒト表皮角化細胞 / 角化細胞 / 表皮 / EGF / Annexin / 信号伝達 / p21 Less

Development of novel tumor marker and targeting-antibody against pancreatic ductal adenocarcinoma
- Principal Investigator
  
  近藤英作
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kansai Medical University
膵癌転移における核膜タンパク質の新たな機能を解明する
- Principal Investigator
  
  山内明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明Principal Investigator
- Principal Investigator
  
  阪口政清
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
原発巣の腫瘍縮小および転移抑制効果を示す膵がん治療薬の開発
- Principal Investigator
  
  木下理恵
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
軸索変性誘導分子SARM1の活性・分解制御によるパーキンソン病治療法の開発
- Principal Investigator
  
  村田等
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Okayama University
乾癬、アトピー性皮膚炎におけるMCAMの意義探求とその制御製剤による病態制御
- Principal Investigator
  
  山本健一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Okayama University
マトリセルラータンパク質阻害によるがん微小環境の破壊と抗腫瘍効果の検討
- Principal Investigator
  
  豊岡伸一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Role of Spred2 in the pathogenesis of cancer and its application for cancer thepapy
- Principal Investigator
  
  MATSUKAWA AKIHIRO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University
Development of therapeutic antibodies based on the elevated S100A8/A9 in tumor microenvironment
- Principal Investigator
  
  Kinoshita Rie
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
Elucidation of the role of S100A8/A9 in pulmonary ischemia-reperfusion injury and development of new therapeutic strategies
- Principal Investigator
  
  Okazaki Mikio
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice
- Principal Investigator
  
  OTANI SHINJI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
  Okayama University
Identification of HRG that is highly inhibitory to S100A8/A9-mediated organ tropic cancer metastasisPrincipal Investigator
- Principal Investigator
  
  Sakaguchi Masakiyo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
Development of novel tumor marker and targeting-antibody against pancreatic ductal adenocarcinoma
- Principal Investigator
  
  Kondo Eisaku
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
Analysis of axonal degeneration mechanism by mitochondrial respiratory suppression in Parkinson's disease
- Principal Investigator
  
  Murata Hitoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Okayama University
Mechanism of NASH pathogenesis by nuclear receptors through qualitative changes in fatty acids
- Principal Investigator
  
  Inoue Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Gunma University
Why cancer cells metastasize to lymphatics from the early stage ?
- Principal Investigator
  
  Yamauchi Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Development of a new treatment strategy for HER2-alterated lung cancer
- Principal Investigator
  
  Soh Junichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kindai University
Novel treatment strategy for malignant pleural mesothelioma targeting the tumor stem cell marker DCLK1
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functions
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Okayama University
Development of the novel therapy focused on damage-associated molecular patterns (DAMPs) for lung fibrosis-related diseases
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Development of new treatments with RAGE-aptamer-incorporated nanoparticles for pulmonary arterial hypertension
- Principal Investigator
  
  Nakamura Kazufumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Okayama University
Mechanistic analysis of an unidentified downstream signals of S100A8/A9 receptors that play a crucial role in acquisition of metastatic force and formation of cancer microenvironment.Principal Investigator
- Principal Investigator
  
  Sakaguchi Masakiyo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
Development of new therapeutic strategy based on gene expression and mutation profiles in EGFR mutant lung cancer
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Basic research of the developmental mechanism and the therapeutic application of NASH by HNF4a and PPARa
- Principal Investigator
  
  Inoue Yusuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Gunma University
Integrated analysis of oncogene candidates MYNN and p53 and elucidation of lung cancer development mechanism
- Principal Investigator
  
  Ito Sachio
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Novel therapeutic method for HER2 active cancer focusing on HER2 novel binding molecule cytokeratin 19
- Principal Investigator
  
  SOH JUNICHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Is the iPS marker "TRA-1-60" an indicator of cancer intractability against therapeutics?
- Principal Investigator
  
  Kondo Eisaku
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
Development of new immunotherapy for lung cancer by combined application of diabetes drug metformin and anti-PD-1 antibody
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Development of new treatments with suppression of RAGE signal for pulmonary hypertension
- Principal Investigator
  
  NAKAMURA Kazufumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Okayama University
exSSSRs-Fc fusion decoys prevent S100A8/A9-mediated cancer metastasis.Principal Investigator
- Principal Investigator
  
  Sakaguchi Masakiyo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
The role of S100A8/A9-Emmprin in the metastasis of melanoma cells.
- Principal Investigator
  
  TSUBOI RYOJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University
Critical role of newly identified S100A8/A9 receptors in lung specific cancer metastasisPrincipal Investigator
- Principal Investigator
  
  Sakaguchi Masakiyo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
Identification of novel targets in the treatment of lung cancer
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Suppression of oncogenic signaling by tumor suppressor REIC/Dkk-3
- Principal Investigator
  
  Kumon Hiromi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Analysis of the pathological mechanism of NASH by the nuclear receptors and establishment of the therapeutic application
- Principal Investigator
  
  Inoue Yusuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Gunma University
炎症を感知する新規内因性リガンドセンサーの作動機構解明とがん進展における役割Principal Investigator
- Principal Investigator
  
  阪口政清
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Application of REIC/Dkk-3 gene therapy on gastrointestinal cancers targeting cancer stem cells
- Principal Investigator
  
  KATAOKA Ken
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University of Science
Investigation of the mechanisms of personalized-cancer vaccination by REIC/Dkk-3 based gene therapy.
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Establishment of protocol for building up monoclonal antibodies targeting cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Masakiyo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor immunology
- Research Institution
  Okayama University
Innovative improvement of cancer therapeutic adenovirus vector carrying REIC gene
- Principal Investigator
  
  HUH Namho
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical oncology
- Research Institution
  Okayama University
New combinatorial approach to peritoneal dissemination of scirrhous gastric carcinoma based REIC/Dkk-3 gene therapy
- Principal Investigator
  
  KATAOKA Ken
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
TIRAP, an Adaptor Protein for TLR2/4, Transduces a signal from RAGE Phosphorylated upon Ligand BindingPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Masakiyo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Okayama University
誤標的された正常細胞をも抗がんに動員する統合的遺伝子治療の新戦略
- Principal Investigator
  
  HUH Namho
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
The molecular function of immortalization-related genes in the regulation of Oncogenic Ras and prostatic carcinogenesis.
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
上皮細胞増殖制御の機能的ハプタンパク質S100Cの機能解明とがん治療への応用
- Principal Investigator
  
  許南浩
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Fundamental research for new molecular mechanism of anticancer resistance in urogenital cancer
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Basic research on treatment of liver failure and prevention against liver fibrosis by transplantation of MAPC-like stem cells established from bone marrow
- Principal Investigator
  
  MIYAZAKI Masahiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Okayama Gakuin University
  Okayama University
Function of REIC/Dkk-3, a putative Wntregulator in normal skin and cancer
- Principal Investigator
  
  KATAOKA Ken, 李代偉
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
S100C/A11を介する新しいTGFβ増殖抑制信号伝達系の発がんにおける意義
- Principal Investigator
  
  HUH Nam-ho
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
S100Cタンパク質を介した新規細胞増殖抑制機構の解明Principal Investigator
- Principal Investigator
  
  阪口政清
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Okayama University
Relevance of genes involved in skin tissue formation to human diseases and its application for regenerative medicine.
- Principal Investigator
  
  HUH Nam-ho
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University

[Book] 週刊「医学のあゆみ」第264巻第12号2018
- Author(s)
  阪口政清
- Total Pages
  70
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-17H03577
[Book] 月刊「細胞」第49巻第3号2017
- Author(s)
  阪口政清、木下理恵、村田等、山本健一、許南浩、日比野利彦
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-17H03577
[Book] 臨床免疫・アレルギー科2017
- Author(s)
  阪口政清, 宮井雅史, 木下理恵, 村田等, 山本健一, 森実真, 岩月啓氏, 許南浩, 坪井良治, 日比野利彦
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-15K14382
[Book] 月刊「細胞」2017
- Author(s)
  阪口政清、木下理恵、村田等、山本健一、許南浩、日比野利彦
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-15K14382
[Book] 月刊「細胞」第49巻第7号2017
- Author(s)
  阪口政清、木下理恵、村田等、山本健一、許南浩、日比野利彦
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-17H03577
[Book] 臨床免疫・アレルギー科2017
- Author(s)
  阪口政清, 宮井雅史, 木下理恵, 村田等, 山本健一, 森実真, 岩月啓氏, 許南浩, 坪井良治, 日比野利彦
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26290039
[Book] 月刊「細胞」2017
- Author(s)
  阪口政清、木下理恵、村田等、山本健一、許南浩、日比野利彦
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-26290039
[Book] 月刊「臨床免疫、アレルギー科」第67巻第6号2017
- Author(s)
  阪口政清、山本真実, 宮井雅史, 木下理恵, 村田等, 山本健一, 森実真, 岩月啓氏, 許南浩, 坪井良治, 日比野利彦
- Total Pages
  10
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-17H03577
[Book] 動物細胞培養・自動化におけるトラブル発生原因と対策2017
- Author(s)
  阪口政清
- Total Pages
  526
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-17H03577
[Book] Surgery Frontier2005
- Author(s)
  阪口政清, 曽根川裕之, 温井孝昌, 許南浩
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface2024
- Author(s)
  Takahashi Tetta、Tomonobu Nahoko、Kinoshita Rie、Yamamoto Ken-ichi、Murata Hitoshi、Komalasari Ni Luh Gede Yoni、...、Honjo Tomoko、Sakaguchi Yoshihiko、Yamauchi Akira、Kuribayashi Futoshi、Kondo Eisaku、Inoue Yusuke、Futami Junichiro、Toyooka Shinichi、Zamami Yoshito、Sakaguchi Masakiyo
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 14 Pages: 1371342-1371342
- DOI
  10.3389/fonc.2024.1371342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
[Journal Article] PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours2024
- Author(s)
  Takihira Shota、Yamada Daisuke、Osone Tatsunori、Takao Tomoka、Sakaguchi Masakiyo、Hakozaki Michiyuki、Itano Takuto、Nakata Eiji、Fujiwara Tomohiro、Kunisada Toshiyuki、Ozaki Toshifumi、Takarada Takeshi
- Journal Title
  
  British Journal of Cancer
  
  Volume: In press Issue: 9 Pages: 1493-1504
- DOI
  10.1038/s41416-024-02632-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18329, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K24461, KAKENHI-PROJECT-23K27439
[Journal Article] The plasma protein HRG is an important factor for preventing sepsis and maintaining homeostatic response2024
- Author(s)
  Nishibori Masahiro、Wake Hidenori、Sakaguchi Masakiyo
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 159 Issue: 2 Pages: 107-111
- DOI
  10.1254/fpj.23027
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2024-03-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27439
[Journal Article] Correction to: Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer2023
- Author(s)
  Takatsu Fumiaki、Suzawa Ken、Tomida Shuta、Thu Yin Min、Sakaguchi Masakiyo、Toji Tomohiro、Ohki Masayoshi、Tsudaka Shimpei、Date Keiichi、Matsuda Naoki、Iwata Kazuma、Zhu Yidan、Nakata Kentaro、Shien Kazuhiko、Yamamoto Hiromasa、Nakayama Akiko、Okazaki Mikio、Sugimoto Seiichiro、Toyooka Shinichi
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 102 Issue: 1 Pages: 147-147
- DOI
  10.1007/s00109-023-02408-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24421, KAKENHI-PROJECT-23K27439
[Journal Article] Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer2023
- Author(s)
  Takatsu F, Suzawa K, Tomida S, Thu YM, Sakaguchi M, Shien K, Yamamoto H, Nakayama A, Okazaki M, Sugimoto S, Toyooka S
- Journal Title
  
  Journal of molecular medicine (Berlin, Germany)
  
  Volume: 101 Issue: 12 Pages: 1603-1614
- DOI
  10.1007/s00109-023-02384-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439, KAKENHI-PROJECT-23K27688
[Journal Article] SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells2023
- Author(s)
  Gao T, Yang X, Fujisawa M, Ohara T, Wang T, Tomonobu N, Sakaguchi M, Yoshimura T, Matsukawa A
- Journal Title
  
  Int J Mol Sci
  
  Volume: 24 Issue: 5 Pages: 4996-4996
- DOI
  10.3390/ijms24054996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19562, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-21H02988, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923
[Journal Article] PPARα activation partially drives NAFLD development in liver-specific Hnf4a-null mice2023
- Author(s)
  Kasano-Camones Carlos Ichiro、Takizawa Masayuki、Ohshima Noriyasu、Saito Chinatsu、Iwasaki Wakana、Nakagawa Yuko、Fujitani Yoshio、Yoshida Ryo、Saito Yoshifumi、Izumi Takashi、Terawaki Shin-Ichi、Sakaguchi Masakiyo、Gonzalez Frank J、Inoue Yusuke
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 5 Pages: 393-411
- DOI
  10.1093/jb/mvad005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-23K06478, KAKENHI-PROJECT-21K08547, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
[Journal Article] STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes.2023
- Author(s)
  Murata H, Yasui Y, Oiso K, Ochi T, Tomonobu N, Yamamoto KI, Kinoshita R, Sakaguchi M
- Journal Title
  
  Cellular Signalling
  
  Volume: 108 Pages: 110717-110717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06884
[Journal Article] Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells.2023
- Author(s)
  Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Junichiro Futami, Lena Audebert, Youyi Chen, Ni Luh Gede Yoni Komalasari, Fan Jiang, Chikako Yoshizawa, Hitoshi Murata, Ken-Ichi Yamamoto, Masami Watanabe, Hiromi Kumon, Masakiyo Sakaguchi
- Journal Title
  
  Journal of molecular medicine (Berlin, Germany)
  
  Volume: 101 Issue: 4 Pages: 431-447
- DOI
  10.1007/s00109-023-02292-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-19H01064, KAKENHI-PROJECT-23K27439
[Journal Article] Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration2023
- Author(s)
  Murata Hitoshi、Phoo May Tha Zin、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Miyazaki Ikuko、Nishibori Masahiro、Asanuma Masato、Sakaguchi Masakiyo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 6 Pages: 533-548
- DOI
  10.1093/jb/mvad068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-23K06928, KAKENHI-PROJECT-21K07415, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
[Journal Article] STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes2023
- Author(s)
  Murata Hitoshi、Yasui Yu、Oiso Kazuma、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Sakaguchi Masakiyo
- Journal Title
  
  Cellular Signalling
  
  Volume: 108 Pages: 110717-110717
- DOI
  10.1016/j.cellsig.2023.110717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
[Journal Article] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A22023
- Author(s)
  Sakaguchi, M., Komalasari, N. L. G. Y., Tomonobu, N., Kinoshita, R., Chen, Y., Sakaguchi, Y., Gohara, Y., Jiang, F., Yamamoto, K., Murata, H., Ruma, I. M. W., Sumardika, I. W., Zhou, J., Yamauchi, A., Kuribayashi, F., Inoue, Y., Toyooka, S.
- Journal Title
  
  Front. Oncol.
  
  Volume: 13 Pages: 1142907-1142907
- DOI
  10.3389/fonc.2023.1142907
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
[Journal Article] LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells2023
- Author(s)
  Daisuke Hirabayashi, Ken-ichi Yamamoto, Akihiro Maruyama, Nahoko Tomonobu, Rie Kinoshita, Youyi Chen, Ni Luh Gede Yoni Komalasari, Hitoshi Murata, Yuma Gohara, Fan Jiang, Jin Zhou, I Made Winarsa Ruma, I Wayan Sumardika, Akira Yamauchi, Futoshi Kuribayashi, Shinichi Toyooka, Yusuke Inoue, Masakiyo Sakaguchi
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 13 Pages: 1142886-1142886
- DOI
  10.3389/fonc.2023.1142886
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06478, KAKENHI-PROJECT-22H04923
[Journal Article] Histidine-Rich Glycoprotein Suppresses the S100A8/A9-Mediated Organotropic Metastasis of Melanoma Cells2022
- Author(s)
  Nahoko Tomonobu, Rie Kinoshita, Hidenori Wake, Yusuke Inoue, ..., Hitoshi Murata, Ken-ichi Yamamoto, I Wayan Sumardika, Youyi Chen, Junichiro Futami, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Shinichi Toyooka, Masahiro Nishibori, Masakiyo Sakaguchi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 18 Pages: 10300-10300
- DOI
  10.3390/ijms231810300
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03527, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Toll-like receptor 4 promotes bladder cancer progression upon S100A8/A9 binding, which requires TIRAP-mediated TPL2 activation2022
- Author(s)
  Acosta Gonzalez Herik Rodrigo, Nahoko Tomonobu, Haruka Yoneda, Rie Kinoshita, ..., Hitoshi Murata, Ken-ichi Yamamoto, Junichiro Futami, Akira Yamauchi, Futoshi Kuribayashi, Yusuke Inoue, Eisaku Kondo, Shinichi Toyooka, Masahiro Nishibori, Masami Watanabe, Yasutomo Nasu, Masakiyo Sakaguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 634 Pages: 83-91
- DOI
  10.1016/j.bbrc.2022.09.116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03527, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Functional Blockage of S100A8/A9 Ameliorates Ischemia Reperfusion Injury in the Lung2022
- Author(s)
  Nakata Kentaro、Okazaki Mikio、Sakaue Tomohisa、Kinoshita Rie、Komoda Yuhei、Shimizu Dai、Yamamoto Haruchika、Tanaka Shin、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Yamamoto Hiromasa、Ohara Toshiaki、Sugimoto Seiichiro、Yamane Masaomi、Matsukawa Akihiro、Sakaguchi Masakiyo、Toyooka Shinichi
- Journal Title
  
  Bioengineering
  
  Volume: 9 Issue: 11 Pages: 673-673
- DOI
  10.3390/bioengineering9110673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09164, KAKENHI-PROJECT-20KK0203, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Inhibiting S100A8/A9 attenuates airway obstruction in a mouse model of heterotopic tracheal transplantation2022
- Author(s)
  Shimizu Dai、Okazaki Mikio、Sugimoto Seiichiro、Kinoshita Rie、Nakata Kentaro、Tanaka Shin、Hashimoto Kohei、Miyoshi Kentaroh、Yamane Masaomi、Matsukawa Akihiro、Sakaguchi Masakiyo、Toyooka Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 629 Pages: 86-94
- DOI
  10.1016/j.bbrc.2022.08.087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09164, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Dkk3/REIC Deficiency Impairs Spermiation, Sperm Fibrous Sheath Integrity and the Sperm Motility of Mice2022
- Author(s)
  Xue Ruizhi、Lin Wenfeng、Fujita Hirofumi、Sun Jingkai、Kinoshita Rie、Ochiai Kazuhiko、Futami Junichiro、Watanabe Masami、Ohuchi Hideyo、Sakaguchi Masakiyo、Tang Zhengyan、Huang Peng、Nasu Yasutomo、Kumon Hiromi
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 2 Pages: 285-285
- DOI
  10.3390/genes13020285
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09625, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-21K09371, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-22H04923
[Journal Article] RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion2021
- Author(s)
  He Fang、Matsumoto Yoshinori、Asano Yosuke、Yamamura Yuriko、Katsuyama Takayuki、La Rose Jose、Tomonobu Nahoko、Komalasari Ni Luh Gede Yoni、Sakaguchi Masakiyo、Rottapel Robert、Wada Jun
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 665273-665273
- DOI
  10.3389/fonc.2021.665273
- NAID
  120007089841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] Presence of Microplastics in Four Types of Shellfish Purchased at Fish Markets in Okayama City, Japan2021
- Author(s)
  Yamamoto Ken-ichi、Oshiki Toshiyuki、Kagawa Hiroko、Namba Masayoshi、Sakaguchi Masakiyo
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 75 Issue: 3 Pages: 381-384
- DOI
  10.18926/AMO/62234
- NAID
  120007089831
- URL
  https://ousar.lib.okayama-u.ac.jp/62234
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β12021
- Author(s)
  Saito Ken、Mitsui Ayaka、Sumardika I. Wayan、Yokoyama Yusuke、Sakaguchi Masakiyo、Kondo Eisaku
- Journal Title
  
  International Journal of Oncology
  
  Volume: 58 Issue: 6 Pages: 29-29
- DOI
  10.3892/ijo.2021.5209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03527, KAKENHI-PROJECT-21K09626, KAKENHI-PROJECT-16H06277
[Journal Article] Corrigendum: RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion2021
- Author(s)
  He Fang、Matsumoto Yoshinori、Asano Yosuke、Yamamura Yuriko、Katsuyama Takayuki、Rose Jose La、Tomonobu Nahoko、Komalasari Ni Luh Gede Yoni、Sakaguchi Masakiyo、Rottapel Robert、Wada Jun
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 729192-729192
- DOI
  10.3389/fonc.2021.729192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516
[Journal Article] Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes2021
- Author(s)
  Tachibana Kota、Tang Nina、Urakami Hitoshi、Kajita Ai、Kobashi Mina、Nomura Hayato、Sasakura Minori、Sugihara Satoru、Jiang Fan、Tomonobu Nahoko、Sakaguchi Masakiyo、Ouchida Mamoru、Morizane Shin
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 12659-12659
- DOI
  10.3390/ijms222312659
- NAID
  120007183235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22739, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K08672, KAKENHI-PROJECT-16H06277
[Journal Article] Oncogenic potential of human pluripotent stem cell‐derived lung organoids with <scp>HER2</scp> overexpression2021
- Author(s)
  Miura Akihiro、Yamada Daisuke、Nakamura Masahiro、Tomida Shuta、Shimizu Dai、Jiang Yan、Takao Tomoka、Yamamoto Hiromasa、Suzawa Ken、Shien Kazuhiko、Yamane Masaomi、Sakaguchi Masakiyo、Toyooka Shinichi、Takarada Takeshi
- Journal Title
  
  International Journal of Cancer
  
  Volume: 149 Issue: 8 Pages: 1593-1604
- DOI
  10.1002/ijc.33713
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-23K21368
[Journal Article] Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A2020
- Author(s)
  Gao Shangze、Wake Hidenori、Sakaguchi Masakiyo、Wang Dengli、Takahashi Youhei、Teshigawara Kiyoshi、Zhong Hui、Mori Shuji、Liu Keyue、Takahashi Hideo、Nishibori Masahiro
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101180-101180
- DOI
  10.1016/j.isci.2020.101180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16H06277
[Journal Article] Cytotoxic Effects of Alcohol Extracts from a Plastic Wrap (Polyvinylidene Chloride) on Human Cultured Liver Cells and Mouse Primary Cultured Liver Cells2020
- Author(s)
  Yamamoto KI, Kagawa H, Arimoto S, Tan XW, Yasui K, Oshiki T, Sakaguchi M.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 74 Issue: 4 Pages: 327-334
- DOI
  10.18926/AMO/60371
- NAID
  120006880210
- URL
  https://ousar.lib.okayama-u.ac.jp/60371
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats2020
- Author(s)
  Nakamura Kazufumi、Akagi Satoshi、Ejiri Kentaro、Yoshida Masashi、Miyoshi Toru、Sakaguchi Masakiyo、Amioka Naofumi、Suastika Luh Oliva Saraswati、Kondo Megumi、Nakayama Rie、Takaya Yoichi、Higashimoto Yuichiro、Fukami Kei、Matsubara Hiromi、Ito Hiroshi
- Journal Title
  
  Journal of Cardiology
  
  Volume: - Issue: 1 Pages: 12-16
- DOI
  10.1016/j.jjcc.2020.12.009
- NAID
  120007182876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K08424, KAKENHI-PROJECT-21K08108
[Journal Article] Analysis of a plasmid encoding botulinum neurotoxin type G gene in Clostridium argentinense2020
- Author(s)
  Sakaguchi, Y., Uchiyama, J., Take, A., Gotoh, K., Sakaguchi, M., Suzuki, T., Yamamoto, Y., Hosomi, K., Kohda, T., Mukamoto, M., Kozaki, S., Hayashi, S., Oguma, K.
- Journal Title
  
  Anaerobe
  
  Volume: 66 Pages: 102281-102281
- DOI
  10.1016/j.anaerobe.2020.102281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07560, KAKENHI-PROJECT-20K16250, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K07127, KAKENHI-PROJECT-16H06277
[Journal Article] Synergistic regulation of hepatic Fsp27b expression by HNF4A and CREBH2020
- Author(s)
  Kasano-Camones CI, Takizawa M, Iwasaki W, Sasaki S, Hamada M, Morimoto A, Sakaguchi M, Gonzalez FJ, Inoue Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 530 Issue: 2 Pages: 432-439
- DOI
  10.1016/j.bbrc.2020.05.070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] PLOD2 Is Essential to Functional Activation of Integrin β1 for Invasion/Metastasis in Head and Neck Squamous Cell Carcinomas.2020
- Author(s)
  Ueki Y, Saito K, Iioka H, Sakamoto I, Kanda Y, Sakaguchi M, Horii A, Kondo E.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 2 Pages: 100850-100850
- DOI
  10.1016/j.isci.2020.100850
- NAID
  120006840775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-20H03527, KAKENHI-PROJECT-16H06277
[Journal Article] Antitumor Effects of Pan-RAF Inhibitor LY3009120 Against Lung Cancer Cells Harboring Oncogenic BRAF Mutation2020
- Author(s)
  MIYAUCHI SHUNSAKU、SHIEN KAZUHIKO、TAKEDA TATSUAKI、ARAKI KOTA、NAKATA KENTARO、MIURA AKIHIRO、TAKAHASHI YUTA、KURIHARA EISUKE、OGOSHI YUSUKE、NAMBA KEI、SUZAWA KEN、YAMAMOTO HIROMASA、OKAZAKI MIKIO、SOH JUNICHI、TOMIDA SHUTA、YAMANE MASAOMI、SAKAGUCHI MASAKIYO、TOYOOKA SHINICHI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 5 Pages: 2667-2673
- DOI
  10.21873/anticanres.14237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-16H06277
[Journal Article] Xylitol acts as an anticancer monosaccharide to induce selective cancer death via regulation of the glutathione level2020
- Author(s)
  Tomonobu Nahoko、Komalasari Ni Luh Gede Yoni、Sumardika I Wayan、Jiang Fan、Chen Youyi、Yamamoto Ken-ichi、Kinoshita Rie、Murata Hitoshi、Inoue Yusuke、Sakaguchi Masakiyo
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 324 Pages: 109085-109085
- DOI
  10.1016/j.cbi.2020.109085
- NAID
  120006892917
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] exMCAM-Fc, an S100A8/A9-mediated-metastasis blocker, efficiently reduced the number of circulating tumor cells that appeared in the blood flow2020
- Author(s)
  Tomonobu Nahoko、Kinoshita Rie、Sakaguchi Masakiyo
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 6 Pages: 4879-4883
- DOI
  10.1007/s11033-020-05495-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility2020
- Author(s)
  Bajkowska Karolina、Sumardika I. Wayan、Tomonobu Nahoko、Chen Youyi、Yamamoto Ken-ichi、Kinoshita Rie、Murata Hitoshi、Gede Yoni Komalasari Ni Luh、Jiang Fan、Yamauchi Akira、Winarsa Ruma I. Made、Kasano-Camones Carlos Ichiro、Inoue Yusuke、Sakaguchi Masakiyo
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 22 Pages: 100768-100768
- DOI
  10.1016/j.bbrep.2020.100768
- NAID
  120006890008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis2020
- Author(s)
  Araki Kota、Kinoshita Rie、Tomonobu Nahoko、Gohara Yuma、Tomida Shuta、Takahashi Yuta、Senoo Satoru、Taniguchi Akihiko、Itano Junko、Yamamoto Ken-ichi、Murata Hitoshi、Suzawa Ken、Shien K、Yamamoto H、Okazaki M、Sugimoto S、Ichimura K、Nishibori M、Miyahara N、Toyooka S、Sakaguchi Masakiyo
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 99 Issue: 1 Pages: 131-145
- DOI
  10.1007/s00109-020-02001-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19H03746, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] S100 Soil Sensor Receptors and Molecular Targeting Therapy Against Them in Cancer Metastasis.2020
- Author(s)
  Tomonobu N, Kinoshita R, Sakaguchi M.
- Journal Title
  
  Transl Oncol
  
  Volume: 3 Issue: 4 Pages: 100753-100753
- DOI
  10.1016/j.tranon.2020.100753
- NAID
  120006869552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K15320
[Journal Article] MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions.2020
- Author(s)
  Sato H, Schoenfeld AJ, Siau E, Lu YC, Tai H, Suzawa K, Kubota D, Lui AJ, Qeriqi B, Mattar M, Offin M, Sakaguchi M, Toyooka S, Drilon A, Rosen N, Kris MG, Solit DB, de Stanchina E, Davare MA, Riely GJ, Ladanyi M, Somwar R.
- Journal Title
  
  Clin Cancer Res
  
  Volume: - Issue: 12 Pages: 2932-2945
- DOI
  10.1158/1078-0432.ccr-19-3321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] Enhancement of intestinal epithelial barrier function by Weissella confusa F213 and Lactobacillus rhamnosus FBB81 probiotic candidates in an in vitro model of hydrogen peroxide-induced inflammatory bowel disease2020
- Author(s)
  Fatmawati Ni Nengah Dwi、Gotoh Kazuyoshi、Mayura I. Putu Bayu、Nocianitri Komang Ayu、Suwardana Gede Ngurah Rsi、Komalasari Ni Luh Gede Yoni、Ramona Yan、Sakaguchi Masakiyo、Matsushita Osamu、Sujaya I. Nengah
- Journal Title
  
  BMC Research Notes
  
  Volume: 13 Issue: 1 Pages: 489-489
- DOI
  10.1186/s13104-020-05338-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] Extracellular S100A11 plays a critical role in spread of the fibroblast population in pancreatic cancers2019
- Author(s)
  Takamatsu H, Yamamoto K, Tomonobu N, Murata H, Inoue Y, Yamauchi A, Sumardika W, Youyi C, Kinoshita R, Yamamura M, Fujiwara H, Mitsui Y, Araki K, Futami J, Saito K, Iioka H, Ruma MW, Putranto EW, Nishibori M, Kondo E, Yamamoto Y, Toyooka S, Sakaguchi M
- Journal Title
  
  Oncol Res
  
  Volume: - Issue: 6 Pages: 713-727
- DOI
  10.3727/096504018x15433161908259
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] PODXL1 promotes metastasis of the pancreatic ductal adenocarcinoma by activating the C5aR/C5a axis from the tumor microenvironment.2019
- Author(s)
  Saito K, Iioka H, Maruyama S, Sumardika IW, Sakaguchi M, Kondo E.
- Journal Title
  
  Neoplasia
  
  Volume: 21 Pages: 1121-1132
- NAID
  120006842043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.2019
- Author(s)
  Tomonobu N, Kinoshita R, Sumardika IW, Chen Y, Inoue Y, Yamauchi A, Yamamoto KI, Murata H, Sakaguchi M.
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 9 Pages: 100619-100619
- NAID
  120006948964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.2019
- Author(s)
  Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
- Journal Title
  
  Neoplasia.
  
  Volume: 21(7) Issue: 7 Pages: 627-640
- DOI
  10.1016/j.neo.2019.04.006
- NAID
  120006948963
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.2019
- Author(s)
  Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M
- Journal Title
  
  Cancer Lett.
  
  Volume: - Pages: 178-190
- DOI
  10.1016/j.canlet.2019.03.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.2019
- Author(s)
  Tomonobu N, Kinoshita R, Sumardika IW, Chen Y, Inoue Y, Yamauchi A, Yamamoto KI, Murata H, Sakaguchi M
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: - Pages: 100619-100619
- DOI
  10.1016/j.bbrep.2019.100619
- NAID
  120006948964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts2019
- Author(s)
  Mitsui Yosuke、Tomonobu Nahoko、Watanabe Masami、Kinoshita Rie、Sumardika I Wayan、Youyi Chen、Murata Hitoshi et al.
- Journal Title
  
  Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  
  Volume: 27 Issue: 8 Pages: 945-956
- DOI
  10.3727/096504019x15555408784978
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations.2019
- Author(s)
  Ogoshi Y, Shien K, Yoshioka T, Torigoe H, Sato H, Sakaguchi M, Tomida S, Namba K, Kurihara E, Takahashi Y, Suzawa K, Yamamoto H, Soh J, Toyooka S
- Journal Title
  
  Oncol Lett.
  
  Volume: - Pages: 2729-2736
- DOI
  10.3892/ol.2019.9908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K10681
[Journal Article] Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1.2019
- Author(s)
  Iioka H, Saito K, Sakaguchi M, Tachibana T, Homma K, Kondo E.
- Journal Title
  
  Int J Cancer
  
  Volume: 145 Issue: 10 Pages: 2740-2753
- DOI
  10.1002/ijc.32336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-17K08737
[Journal Article] Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression.2019
- Author(s)
  Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M
- Journal Title
  
  Mol Carcinog.
  
  Volume: - Issue: 6 Pages: 980-995
- DOI
  10.1002/mc.22987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Hepatocyte nuclear factor 4α regulates megalin expression in proximal tubular cells.2019
- Author(s)
  Sasaki S, Hara A, Sakaguchi M, Nangaku M, Inoue Y.
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 17 Pages: 87-92
- DOI
  10.1016/j.bbrep.2018.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-17H03577
[Journal Article] Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B2019
- Author(s)
  Nishimura Yoshito、Wake Hidenori、Teshigawara Kiyoshi、Wang Dengli、Sakaguchi Masakiyo、Otsuka Fumio、Nishibori Masahiro
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 7 Issue: 3
- DOI
  10.1002/prp2.481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17H03577
[Journal Article] S100タンパク質に着眼したがん転移機構の解明とその制御.2018
- Author(s)
  阪口政清
- Journal Title
  
  岡山医学会雑誌
  
  Volume: 130 Pages: 135-139
- NAID
  130007542849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma2018
- Author(s)
  Sato Hiroki、Sakaguchi Masakiyo、Yamamoto Hiromasa、Tomida Shuta、Aoe Keisuke、Shien Kazuhiko、Yoshioka Takahiro、Namba Kei、Torigoe Hidejiro、Soh Junichi、Tsukuda Kazunori、Tao Hiroyuki、Okabe Kazunori、Miyoshi Shinichiro、Pass Harvey I.、Toyooka Shinichi
- Journal Title
  
  Oncogenesis
  
  Volume: 7 Issue: 1 Pages: 11-11
- DOI
  10.1038/s41389-017-0017-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-17H03577
[Journal Article] Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.2018
- Author(s)
  Sato H, Yamamoto H, Sakaguchi M, Shien K, Tomida S, Shien T, Ikeda H, Hatono M, Torigoe H, Namba K, Yoshioka T, Kurihara E, Ogoshi Y, Takahashi Y, Soh J, Toyooka S
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 10 Pages: 3183-3196
- DOI
  10.1111/cas.13763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Therapeutic strategies for afatinib-resistant lung cancer harboring HER2 alterations2018
- Author(s)
  Torigoe Hidejiro、Shien Kazuhiko、Takeda Tatsuaki、Yoshioka Takahiro、Namba Kei、Sato Hiroki、suzawa Ken、Yamamoto Hiromasa、Soh Junichi、Sakaguchi Masakiyo、Tomida Shuta、Tsukuda Kazunori、Miyoshi Shinichiro、Toyooka Shinichi
- Journal Title
  
  Cancer Sci.
  
  Volume: - Issue: 5 Pages: 1493-1502
- DOI
  10.1111/cas.13571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K16608
[Journal Article] Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.2018
- Author(s)
  Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 136(3) Issue: 3 Pages: 97-106
- DOI
  10.1016/j.jphs.2017.11.003
- NAID
  130007902144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K15580
[Journal Article] Tumor-suppressive effect of LRIG1, a negative regulator of ErbB, in non-small cell lung cancer harboring mutant EGFR2018
- Author(s)
  Torigoe H, Yamamoto H, Sakaguchi M, Youyi C, Numba K, Sato H, Shien K, Soh J, Suzawa K, Tomida S, Tsukuda K, Miyoshi S, Toyooka S
- Journal Title
  
  Carcinogenesis
  
  Volume: - Issue: 5 Pages: 719-727
- DOI
  10.1093/carcin/bgy044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-18K08783
[Journal Article] exSSSRs (extracellular S100 soil sensor receptors)-Fc fusion proteins work as prominent decoys to S100A8/A9-induced lung tropic cancer metastasis.2018
- Author(s)
  Kinoshita R, Sato H, Yamauchi A, Takahashi Y, Inoue Y, Sumardika IW, Chen Y, Tomonobu N, Araki K, Shien K, Tomida S, Torigoe H, Namba K, Kurihara E, Ogoshi Y, Murata H, Yamamoto KI, Futami J, Putranto EW, Ruma IMW, Yamamoto H, Soh J, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M
- Journal Title
  
  Int J Cancer.
  
  Volume: - Issue: 12 Pages: 3138-3145
- DOI
  10.1002/ijc.31945
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD(+) cleavage activity to inhibit mitochondrial respiration.2018
- Author(s)
  Murata H, Khine CC, Nishikawa A, Yamamoto KI, Kinoshita R, Sakaguchi M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 293 Issue: 49 Pages: 18933-18943
- DOI
  10.1074/jbc.ra118.004578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-18K15320
[Journal Article] Newly developed anti-S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis.2018
- Author(s)
  Kinoshita R, Sato H, Yamauchi A, Takahashi Y, Inoue Y, Sumardika IW, Chen Y, Tomonobu N, Araki K, Shien K, Tomida S, Torigoe H, Namba K, Kurihara E, Ogoshi Y, Murata H, Yamamoto KI, Futami J, Putranto EW, Ruma IMW, Yamamoto H, Soh J, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
- Journal Title
  
  Int J Cancer.
  
  Volume: 印刷中 Issue: 2 Pages: 569-575
- DOI
  10.1002/ijc.31982
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Stromal mesenchymal stem cells facilitate pancreatic cancer progression by regulating specific secretory molecules through mutual cellular interaction.2018
- Author(s)
  Saito K, Sakaguchi M, Maruyama S, Iioka H, Putranto EW, Sumardika IW, Tomonobu N, Kawasaki T, Homma K, Kondo E.
- Journal Title
  
  J Cancer.
  
  Volume: 9(16) Issue: 16 Pages: 2916-2929
- DOI
  10.7150/jca.24415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09740, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590
[Journal Article] Induction of Hepatic Metabolic Functions by a Novel Variant of Hepatocyte Nuclear Factor 4γ.2018
- Author(s)
  Sasaki S, Urabe M, Maeda T, Suzuki J, Irie R, Suzuki M, Tomaru Y, Sakaguchi M, Gonzalez FJ, Inoue Y
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 38 Issue: 24
- DOI
  10.1128/mcb.00213-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K08728
[Journal Article] Tumor necrosis factor-α downregulates the REIC/Dkk-3 tumor suppressor gene in normal human skin keratinocytes2018
- Author(s)
  Kataoka Ken、Maehara Natsumi、Ayabe Yuki、Murata Hitoshi、Huh Nam-Ho、Sakaguchi Masakiyo
- Journal Title
  
  Mol Med Rep.
  
  Volume: 17 Pages: 6661-6666
- DOI
  10.3892/mmr.2018.8676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K01303, KAKENHI-PROJECT-16K19037
[Journal Article] Embigin Promotes Prostate Cancer Progression by S100A4-Dependent and-Independent Mechanisms.2018
- Author(s)
  Ruma IMW, Kinoshita R, Tomonobu N, Inoue Y, Kondo E, Yamauchi A, Sato H, Sumardika IW, Chen Y, Yamamoto KI, Murata H, Toyooka S, Nishibori M, Sakaguchi M
- Journal Title
  
  Cancers (Basel)
  
  Volume: 10 Issue: 7 Pages: 239-239
- DOI
  10.3390/cancers10070239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-18K15320
[Journal Article] Crucial role of rage in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension.2018
- Author(s)
  Nakamura K, Sakaguchi M, Matsubara H, Akagi S, Sarashina T, Ejiri K, Akazawa K, Kondo M, Nakagawa K, Yoshida M, Miyoshi T, Ogo T, Oto T, Toyooka S, Higashimoto Y, Fukami K, Ito H.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 9 Pages: 1-11
- DOI
  10.1371/journal.pone.0203046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
[Journal Article] Signal Diversity of Receptor for Advanced Glycation End Products2017
- Author(s)
  Sakaguchi M, Kinoshita R, Putranto EW, Ruma IMW, Sumardika IW, Youyi C, Tomonobu N, Yamamoto KI, Murata H.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 71 Issue: 6 Pages: 459-465
- DOI
  10.18926/AMO/55582
- NAID
  120006370709
- URL
  https://ousar.lib.okayama-u.ac.jp/55582
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
[Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements2017
- Author(s)
  Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M.
- Journal Title
  
  Oncol Rep
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14382
[Journal Article] Identification of a novel component leading to anti-tumor activity besides the major ingredient cordycepin in Cordyceps militaris extract.2017
- Author(s)
  Wada T, Sumardika IW, Saito S, Ruma IMW, Kondo E, Shibukawa M, Sakaguchi M
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci.
  
  Volume: - Pages: 209-219
- DOI
  10.1016/j.jchromb.2017.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K15245
[Journal Article] Identification of a novel component leading to anti-tumor activity besides the major ingredient cordycepin in Cordyceps militaris extract2017
- Author(s)
  Wada T, Sumardika IW, Saito S, Ruma IM, Kondo E, Shibukawa M, Sakaguchi M.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci.
  
  Volume: - Pages: 209-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies.2017
- Author(s)
  Suzawa K, Shien K, Peng H, Sakaguchi M, Watanabe M, Hashida S, Maki Y, Yamamoto H, Tomida S, Soh J, Asano H, Tsukuda K, Nasu Y, Kumon H, Miyoshi S, Toyooka S.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Issue: 1 Pages: 301-307
- DOI
  10.21873/anticanres.11321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382
[Journal Article] Promising therapeutic efficacy of a novel REIC/Dkk-3 expressing adenoviral vector for hepatocellular carcinoma.2017
- Author(s)
  Sawahara H, Shiraha H, Uchida D, Kato H, Kato R, Oyama A, Nagahara T, Iwamuro M, Horiguchi S, Tsutsumi K, Mandai M, Mimura T, Wada N, Takeuchi Y, Kuwaki K, Onishi H, Nakamura S, Watanabe M, Sakaguchi M, et al.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: - Issue: 10 Pages: 1769-1777
- DOI
  10.1111/jgh.13757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-15H04974, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K08999, KAKENHI-PROJECT-15K09001
[Journal Article] An HNF4α-microRNA-194/192 signaling axis maintains hepatic cell function.2017
- Author(s)
  Morimoto A, Kannari M, Tsuchida Y, Sasaki S, Saito C, Matsuta T, Maeda T, Akiyama M, Nakamura T, Sakaguchi M, Nameki N, Gonzalez FJ, and Inoue Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Issue: 25 Pages: 10574-10585
- DOI
  10.1074/jbc.m117.785592
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K06945
[Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements2017
- Author(s)
  Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M
- Journal Title
  
  Oncol Rep
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290039
[Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene.2017
- Author(s)
  Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, and Sakaguchi M.
- Journal Title
  
  Oncol. Lett.
  
  Volume: 14 Issue: 1 Pages: 1041-1048
- DOI
  10.3892/ol.2017.6201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K08785, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K01303, KAKENHI-PROJECT-16K18440
[Journal Article] ｂ-1,3-galactosyl-O-glycosyl-glycoprotein ｂ-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.2017
- Author(s)
  Sumardika I Wayan、Youyi Chen、Kondo Eisaku、Inoue Yusuke、Ruma I Made Winarsa、Murata Hitoshi、Kinoshita Rie、Yamamoto Ken-Ichi、Tomida Shuta、Shien Kazuhiko、Satoh Hiroki、Yamauchi Akira、Futami Junichiro、Putranto Endy Widya、Hibino Toshihiko、Toyooka Shinichi、Nishibori Masahiro、Sakaguchi Masakiyo
- Journal Title
  
  Oncology Reserch
  
  Volume: in press Issue: 3 Pages: 431-444
- DOI
  10.3727/096504017x15031557924123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K15245, KAKENHI-PROJECT-16K18440, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-18K15320
[Journal Article] S100-SPECT uncovers cellular and molecular events of pre-metastatic niche formation and following organ-specific cancer metastasis2017
- Author(s)
  Sakaguchi Masakiyo
- Journal Title
  
  Theranostics
  
  Volume: 7 Issue: 10 Pages: 2649-2651
- DOI
  10.7150/thno.19866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies2017
- Author(s)
  Suzawa K, Shien K, Peng H, Sakaguchi M, Watanabe M, Hashida S, Maki Y, Yamamoto H, Tomida S, Soh J, Asano H, Tsukuda K, Nasu Y, Kumon H, Miyoshi S, Toyooka S.
- Journal Title
  
  Anticancer Res
  
  Volume: 14 Pages: 301-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03577
[Journal Article] Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK12017
- Author(s)
  Xu Jiaqi、Sadahira Takuya、Kinoshita Rie、Li ShunAi、Huang Peng、Wada Koichiro、Araki Motoo、Ochiai Kazuhiko、Noguchi Hirofumi、Sakaguchi Masakiyo、Nasu Yasutomo、Watanabe Masami
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Pages: 5638-5642
- DOI
  10.3892/ol.2017.6833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11138, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
[Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene2017
- Author(s)
  1.Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, Sakaguchi M
- Journal Title
  
  Oncol Lett
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290039
[Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene2017
- Author(s)
  Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, Sakaguchi M.
- Journal Title
  
  Oncol Lett.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14382
[Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements.2017
- Author(s)
  Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M.
- Journal Title
  
  Oncology Reports
  
  Volume: 38 Issue: 2 Pages: 1108-1114
- DOI
  10.3892/or.2017.5710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11004, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
[Journal Article] Modulation of leukotriene B4 receptor 1 signaling by receptor for advanced glycation end products, RAGE.2016
- Author(s)
  Ichiki T, Koga T, Okuno T, Saeki K, Yamamoto Y, Yamamoto H, Sakaguchi M, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 30 Issue: 5 Pages: 1811-1822
- DOI
  10.1096/fj.201500117
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19032, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-13J02797, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320
[Journal Article] Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells.2016
- Author(s)
  Saho S, Satoh H, Kondo E, Inoue Y, Yamauchi A, Murata H, Kinoshita R, Yamamoto KI, Futami J, Putranto EW, Ruma IM, Sumardika IW, Youyi C, Suzawa K, Yamamoto H, Soh J, Tomida S, Sakaguchi Y, Saito K, Iioka H, Huh NH, Toyooka S, Sakaguchi M.
- Journal Title
  
  Cancer Microenviron.
  
  Volume: 9 Issue: 2-3 Pages: 93-105
- DOI
  10.1007/s12307-016-0185-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K08785, KAKENHI-PROJECT-16K15245
[Journal Article] Histidine-rich glycoprotein prevents septic lethality through regulation of immunothrombosis and inflammation.2016
- Author(s)
  Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H, Nishibori M.
- Journal Title
  
  EBioMedicine
  
  Volume: 9 Pages: 180-194
- DOI
  10.1016/j.ebiom.2016.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.2016
- Author(s)
  Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 39557-39557
- DOI
  10.1038/srep39557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-26293318, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-16K10681
[Journal Article] Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.2016
- Author(s)
  Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 33319-33319
- DOI
  10.1038/srep33319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26462182, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26670644
[Journal Article] Identification of an S100A8 receptor neuroplastin-β and its heterodimer formation with EMMPRIN.2016
- Author(s)
  Sakaguchi M, Yamamoto M, Miyai M, Maeda T, Hiruma J, Murata H, Kinoshita R, Ruma IM, Putranto EW, Inoue Y, Morizane S, Huh NH, Tsuboi R, Hibino T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136 Issue: 11 Pages: 2240-2250
- DOI
  10.1016/j.jid.2016.06.617
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26860899, KAKENHI-PROJECT-16K08728
[Journal Article] Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations2016
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Mizuki Morita, Hiromasa Yamamoto, Shuta Tomida, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda and Shinichiro Miyoshi
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 1 Pages: 45-52
- DOI
  10.1111/cas.12845
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293318, KAKENHI-PROJECT-26293352
[Journal Article] MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding.2016
- Author(s)
  Ruma IM, Putranto EW, Kondo E, Murata H, Watanabe M, Huang P, Kinoshita R, Futami J, Inoue Y, Yamauchi A, Sumardika IW, Youyi C, Yamamoto K, Nasu Y, Nishibori M, Hibino T, Sakaguchi M.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 33 Issue: 6 Pages: 609-627
- DOI
  10.1007/s10585-016-9801-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K20093, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K15245
[Journal Article] Novel REIC/Dkk-3-encoding adenoviral vector as a promising therapeutic agent for pancreatic cancer.2016
- Author(s)
  Sawahara H, Shiraha H, Uchida D, Kato H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Sakaguchi M, Takaki A, Nouso K, Nasu Y, Kumon H, Okada H
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 23 Issue: 8 Pages: 278-283
- DOI
  10.1038/cgt.2016.31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K09001
[Journal Article] TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells2015
- Author(s)
  Otani H, Yamamoto H, Takaoka M, Sakaguchi M, Soh J, Jida M, Ueno T, Kubo T, Asano H, Tsukuda K, Kiura K, Hatakeyama S, Kawahara E, Naomoto Y, Miyoshi S, Toyooka S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0129838-e0129838
- DOI
  10.1371/journal.pone.0129838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-25293302, KAKENHI-PROJECT-26290039
[Journal Article] The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression.2015
- Author(s)
  Kinoshita R, Watanabe M, Huang P, Li SA, Sakaguchi M, Kumon H, Futami J.
- Journal Title
  
  Oncology Reports
  
  Volume: In press Issue: 6 Pages: 2908-2914
- DOI
  10.3892/or.2015.3885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26290039
[Journal Article] NRF2 regulates PINK1 expression under oxidative stress conditions2015
- Author(s)
  Murata H, Takamatsu H, Liu S, Kataoka K, Huh NH, Sakaguchi M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 11 Pages: e0142438-e0142438
- DOI
  10.1371/journal.pone.0142438
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-25860216, KAKENHI-PROJECT-26290039
[Journal Article] Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver2015
- Author(s)
  Matsuo S, Ogawa M, Muckenthaler MU, Mizui Y, Sasaki S, Fujimura T, Takizawa M, Ariga N, Ozaki H, Sakaguchi M, Gonzalez FJ, Inoue Y
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 52 Pages: 30855-30865
- DOI
  10.1074/jbc.m115.694414
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-26290039
[Journal Article] Preclinical Evaluation of MicroRNA-34b/c Delivery for Malignant Pleural Mesothelioma2014
- Author(s)
  Ueno T, Toyooka S, Fukazawa T, Kubo T, Soh J, Asano H, Muraoka T, Tanaka N, Maki Y, Shien K, Furukawa M, Sakaguchi M, Yamamoto H, Tsukuda K, Miyoshi S
- Journal Title
  
  Acta Med Okayama
  
  Volume: 68 Pages: 23-26
- NAID
  120005372648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290039
[Journal Article] Novel germ-line mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas2014
- Author(s)
  Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S
- Journal Title
  
  J Natl Cancer Inst
  
  Volume: 106
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Dramatic increase in expression of a transgene by insertion of promoters downstream of the cargo gene2014
- Author(s)
  Sakaguchi M, Watabe M, Kinoshita R, Kaku H, Ueki H, Futami J, Murata H, Inoue Y, Li SA, Huang P, Putranto EW, Ruma IMW, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Mol Biotech
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Extract of Cordyceps militaris inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells.2014
- Author(s)
  Ruma IMW, Putranto EW, Kondo E, Watanabe R, Saito K, Inoue Y, Yamamoto K, Nakata S,Kaihata M, Murata H and Sakaguchi M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 45(1) Issue: 1 Pages: 209-18
- DOI
  10.3892/ijo.2014.2397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25290062, KAKENHI-PROJECT-25460488, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25670263, KAKENHI-PROJECT-26290039
[Journal Article] SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria2014
- Author(s)
  Murata H, Sakaguchi M, Kataoka K, Huh NH
- Journal Title
  
  Mol Biol Cell
  
  Volume: 24 Pages: 2772-2784
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan2014
- Author(s)
  Sakaguchi Y, Hosomi K, Uchiyama J, Ogura Y, Umeda K, Sakaguchi M, Kohda T, Mukamoto M, Misawa N, Matsuzaki S, Hayashi T, Kozaki S
- Journal Title
  
  Genome Announc
  
  Volume: 2
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer2014
- Author(s)
  Shien K, Tanaka N, Watanabe M, Soh J, Sakaguchi M, Matsuo K, Yamamoto H, Furukawa M, Asano H, Tsukuda K, Nasu Y, Huh NH, Miyoshi S, Kumon H, Toyooka S
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 2 Pages: e87900-e87900
- DOI
  10.1371/journal.pone.0087900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26670627
[Journal Article] Preclinical Evaluation of MicroRNA-34b/c Delivery for Malignant Pleural Mesothelioma2014
- Author(s)
  Ueno T, Toyooka S, Fukazawa T, Kubo T, Soh J, Asano H, Muraoka T, Tanaka N, Maki Y, Shien K, Furukawa M, Sakaguchi M, Yamamoto H, Tsukuda K, Miyoshi S
- Journal Title
  
  Acta Med Okayama
  
  Volume: 68 Pages: 23-26
- NAID
  120005372648
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan.2014
- Author(s)
  Sakaguchi, Y., Hosomi, K., Uchiyama, J., Ogura, Y., Umeda, K., Sakaguchi, M., Kohda, T., Mukamoto, M., Misawa, N., Matsuzaki, S., Hayashi, T., Kozaki, S.
- Journal Title
  
  Genome Announc.
  
  Volume: 23 Issue: 1
- DOI
  10.1128/genomea.01010-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24580447, KAKENHI-PROJECT-24791025, KAKENHI-PROJECT-25460541, KAKENHI-PROJECT-26290039
[Journal Article] A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector2014
- Author(s)
  Watanabe M., Sakaguchi M., Kinoshita R., Kaku H., Ariyoshi Y., Ueki H., Tanimoto R., Ebara S., Ochiai K., Futami J., Li SA., Huang P., Nasu Y., Huh NH., Kumon H
- Journal Title
  
  Oncology Reports
  
  Volume: 31巻 Issue: 3 Pages: 1089-95
- DOI
  10.3892/or.2013.2958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24780313, KAKENHI-PROJECT-25462479, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
[Journal Article] A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector2014
- Author(s)
  Watanabe M, Sakaguchi M, Kinoshita R, Kaku H, Ariyoshi Y, Ueki H, Tanimoto R, Ebara S, Ochiai K, Futami J, Li SA, Huang P, Nasu Y, Huh NH, Kumon H
- Journal Title
  
  Oncol Rep
  
  Volume: 31 Pages: 1089-1095
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer2014
- Author(s)
  Shien K, Tanaka N, Watanabe M, Soh J, Sakaguchi M, Matsuo K, Yamamoto H, Furukawa M, Asano H, Tsukuda K, Nasu Y, Huh NH, Miyoshi S, Kumon H, Toyooka S
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells2014
- Author(s)
  aiswal JK, Lauritzen SP, Scheffer L, Sakaguchi M, Bunkenborg J, Simon SM, Kallunki T, Jäättelä M, Nylandsted J
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3795-3795
- DOI
  10.1038/ncomms4795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290039
[Journal Article] Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas.2014
- Author(s)
  Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S.
- Journal Title
  
  J Natl Cancer Inst
  
  Volume: 106 Issue: 1
- DOI
  10.1093/jnci/djt338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-25670399, KAKENHI-PROJECT-26290039
[Journal Article] DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes2014
- Author(s)
  Sakaguchi M, Murata H, Aoyama Y, Hibino T, Putranto EW, Ruma IM, Inoue Y, Sakaguchi Y, Yamamoto K, Kinoshita R, Futami J, Kataoka K, Iwatsuki K, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 34 Pages: 23389-23402
- DOI
  10.1074/jbc.m114.573071
- NAID
  120006333870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591943, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25460541, KAKENHI-PROJECT-25860216, KAKENHI-PUBLICLY-26106725, KAKENHI-PROJECT-26290039
[Journal Article] Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene2014
- Author(s)
  Masakiyo Sakaguchi, Masami Watanabe, Rie Kinoshita, Haruki Kaku, Hideo Ueki, Junichiro Futami, Hitoshi Murata, Yusuke Inoue, Shun-Ai Li, Peng Huang, Endy Widya Putranto, I. Made, Winarsa Ruma, Yasutomo Nasu, Hiromi Kumon, Nam-ho Huh
- Journal Title
  
  Mol. Biotechnol
  
  Volume: 56 Issue: 7 Pages: 621-630
- DOI
  10.1007/s12033-014-9738-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23360370, KAKENHI-PROJECT-24390368, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
[Journal Article] Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells2014
- Author(s)
  Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E
- Journal Title
  
  Oncogene
  
  Volume: 33 Pages: 1274-1286
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria2013
- Author(s)
  Murata H, Sakaguchi M, Kataoka K, Huh NH
- Journal Title
  
  Mol Biol Cell
  
  Volume: 24 Pages: 2772-2784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells2013
- Author(s)
  Yamamoto K, Murata H, Putranto EW, Kataoka K, Motoyama A, Hibino T, Inoue Y, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Pages: 1073-1079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells2013
- Author(s)
  Saito K and Sakaguchi M
- Journal Title
  
  Oncogene
  
  Volume: in press Issue: 10 Pages: 1274-1286
- DOI
  10.1038/onc.2013.66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608, KAKENHI-PROJECT-23650625, KAKENHI-PLANNED-24108006, KAKENHI-PUBLICLY-25112716, KAKENHI-PROJECT-25290062, KAKENHI-PROJECT-25670263, KAKENHI-PROJECT-26290039, KAKENHI-PUBLICLY-24117711
[Journal Article] DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells2013
- Author(s)
  Yamamoto K, Murata H, Putranto EW, Kataoka K, Motoyama A, Hibino T, Inoue Y, Sakaguchi M, and Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Issue: 3 Pages: 1073-1079
- DOI
  10.3892/or.2012.2191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590354, KAKENHI-PROJECT-25460490
[Journal Article] DOCK7 is a critical regulator of RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells2013
- Author(s)
  Yamamoto KI, Murata H, Putranto EW, Kataoka K, Motoyama A, Hibino T, Inoue Y, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Pages: 1073-1079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells2013
- Author(s)
  Yamamoto K, Murata H, Putranto EW, Kataoka K, Motoyama A, Hibino T, Inoue Y, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Pages: 1073-1079
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] Inhibition of RAGE signaling by intracellular delivered-inhibitor peptides using PEI-cationization2013
- Author(s)
  Putranto EW, Murata H, Yamamoto K, Kataoka K, Yamada H, Futami J, Sakaguchi M, Huh NH
- Journal Title
  
  Int J Mol Med
  
  Volume: 32 Pages: 938-944
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells2013
- Author(s)
  Yamamoto K, Murata H, Putranto EW, Kataoka K, Motoyama A, Hibino T, Inoue Y, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Pages: 1073-1079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis2013
- Author(s)
  Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, Shimokata T, Ito T, Tsuboi R, Huh NH
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 172-183
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117711
[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis2013
- Author(s)
  Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, Shimokata T, Ito T, Tsuboi R, Huh NH
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 172-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Inhibition of RAGE signaling by intracellularly delivered-inhibitor peptides using PEI-cationization2013
- Author(s)
  Putranto EW, Murata H, Yamamoto KI, Kataoka K, Yamada H, Futami J, Sakaguchi M, Huh NH
- Journal Title
  
  Int J Mol Med
  
  Volume: 32 Pages: 938-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis2013
- Author(s)
  Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, Shimokata T, Ito T, Tsuboi R, Huh NH
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 172-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by down-regulation of BRPK/PINK12012
- Author(s)
  6. Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 27 Pages: 695-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M, Watanabe M, Kaku H, Li SA, Noguchi H, Ueki H, Sakaguchi M, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Int J Oncol
  
  Volume: 28 Pages: 1645-1652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products2012
- Author(s)
  Kataoka K, Ono T, Murata H, Morishita M, Yamamoto K, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Lett
  
  Volume: 3 Pages: 1149-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK12012
- Author(s)
  Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 27 Pages: 695-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia.2012
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products2012
- Author(s)
  Kataoka K, Ono T, Murata H, Morishita M, Yamamoto KI, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Lett
  
  Volume: 3 Pages: 1149-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia2012
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 37 Pages: 428-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK12012
- Author(s)
  Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 27 Pages: 695-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] S100A7 Promotes the Migration and Invasion of Osteosarcoma Cells via Receptor for Advanced Glycation End Products2012
- Author(s)
  Kataoka K, Ono T, Murata H, Morishita M, Yamamoto KI, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Lett
  
  Volume: 3 Pages: 1149-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia2012
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 37 Pages: 428-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591943
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia.2012
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer2012
- Author(s)
  Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66 Pages: 7-16
- NAID
  120003850603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer.2012
- Author(s)
  Hirata et al.
- Journal Title
  
  Int J Oncol.
  
  Volume: 41 Issue: 2 Pages: 559-564
- DOI
  10.3892/ijo.2012.1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501013, KAKENHI-PROJECT-22616004, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-23659213, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
[Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012
- Author(s)
  Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Int J Oncol
  
  Volume: 41 Pages: 559-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia2012
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 37 Pages: 428-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Preclinical safety and efficacy of in situ REIC/Dkk-3 gene therapy for prostate cancer2012
- Author(s)
  Kawauchi K., Watanabe M., Kaku H., Huang P., Sasaki K., Sakaguchi M., Ochiai K., Huh NH., Nasu Y., Kumon H
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66巻 Pages: 7-16
- NAID
  120003850603
- URL
  http://escholarship.lib.okayama-u.ac.jp/amo/vol66/iss1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382
[Journal Article] REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer2012
- Author(s)
  Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Int J Oncol
  
  Volume: 41 Pages: 559-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M, Watanabe M, Kaku H, Li SA, Noguchi H, Ueki H, Sakaguchi M, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Int J Oncol
  
  Volume: 28 Pages: 1645-1652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK1.2012
- Author(s)
  Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H
- Journal Title
  
  Huh NH. Oncol Rep.
  
  Volume: 27(3) Pages: 695-9
- DOI
  10.3892/or.2011.1543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390441, KAKENHI-PROJECT-22791473, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
[Journal Article] S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products2012
- Author(s)
  Kataoka K, Ono T, Murata H, Morishita M, Yamamoto K, Sakaguchi M, Huh NH
- Journal Title
  
  Oncol Lett
  
  Volume: 3 Pages: 1149-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer2012
- Author(s)
  Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66 Pages: 7-16
- NAID
  120003850603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M., Watanabe M., Kaku H., Li SA., Noguchi H., Ueki H., Sakaguchi M., Huh NH., Nasu Y., Kumon H
- Journal Title
  
  Oncol Rep
  
  Volume: 28巻 Issue: 5 Pages: 1645-1652
- DOI
  10.3892/or.2012.2001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390316, KAKENHI-PUBLICLY-24117711
[Journal Article] Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer2012
- Author(s)
  Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66 Pages: 7-16
- NAID
  120003850603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK12012
- Author(s)
  Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 27 Pages: 695-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis2011
- Author(s)
  Du G, Kataoka K, Sakaguchi M, Abarzua F, Than SS, Sonegawa H, Makino T, Shimizu T, Huh NH
- Journal Title
  
  Exp Dermtol
  
  Volume: 20 Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Multiple functions of PINK1 at different intracellular locations: Beyond neuro-degenerative diseases2011
- Author(s)
  Murata H, Sakaguchi M, Kataoka K, Huh NH
- Journal Title
  
  Cell Cycle
  
  Volume: 10 Pages: 1518-1519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Intraperitoneal administration of an adenovirus vector carrying REIC/Dkk-3 gene suppresses peritoneal dissemination of scirrhous gastric carcinoma2011
- Author(s)
  Than SS, Kataoka K, Sakaguchi M, Murata H, Abarzua F, Taketa C, Du G, Yashiro M, Yanagihara K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 25 Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Multiple functions of PINK1 at different intracellular locations: Beyond neuro-degenerative diseases2011
- Author(s)
  Murata H, Sakaguchi M, Kataoka K, Huh NH
- Journal Title
  
  Cell Cycle
  
  Volume: 10 Pages: 1518-1519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A new cytosolic pathway from a Parkinson's disease-associated kinase, BRPK/PINK1 : activation of AKT via MTORC2.2011
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami JI, Yamada H, Kataoka K, Huh NH.
- Journal Title
  
  J Biol Chem. 286
  
  Pages: 7182-7189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] S100A11, a dual growth regulator of epidermal keratinocytes2011
- Author(s)
  Sakaguchi M, Huh NH
- Journal Title
  
  Amino Acids
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding2011
- Author(s)
  Sakaguchi M, Murata H, Yamamoto KI, Ono T, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011
- Author(s)
  Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 391-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011
- Author(s)
  Ochiai, K., Watanabe, M., Ueki, H., Huang, P., Fujii, Y., Nasu, Y., Sakaguchi, M., Huh, NH., Kashiwakura, Y., Kaku, H., and Kumon, H.
- Journal Title
  
  Biochem. Biophy. Res. Com
  
  Volume: 412(2) Issue: 2 Pages: 391-395
- DOI
  10.1016/j.bbrc.2011.07.109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791476, KAKENHI-PROJECT-23390382
[Journal Article] Markedly elevated serum levels of calcium-binding S100A8/A9 proteins in psoriatic arthritis are due to activated monocytes/macrophages2011
- Author(s)
  Aochi S, Tsuji K, Sakaguchi M, Huh NH, Tsuda T, Yamanishi K, Komine M, Iwatsuki K
- Journal Title
  
  J Am Acad Dermatol
  
  Volume: 64 Pages: 879-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011
- Author(s)
  Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 391-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis.2011
- Author(s)
  Du G, Kataoka K, Sakaguchi M, Abarzua F, Than SS, Sonegawa H, Makino T, Shimizu T, Huh NH.
- Journal Title
  
  Exp Dermatol. 20
  
  Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding2011
- Author(s)
  Sakaguchi M
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 8 Pages: e23132-e23132
- DOI
  10.1371/journal.pone.0023132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699, KAKENHI-PROJECT-23790479
[Journal Article] A novel tumor suppressor. REIC/Dkk-3 gene identified by our in vitro transformation model of normal human fibroblasts works as a potent therapeuticaoti-tumor agent2011
- Author(s)
  Sakaguchi M
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 720 Pages: 209-215
- DOI
  10.1007/978-1-4614-0254-1_17
- ISBN
  9781461402534, 9781461402541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Markedly elevated serum levels of calcium-binding S100A8/A9 proteins in psoriatic arthritis are due to activated monocytes/macrophages2011
- Author(s)
  Aochi S, Tsuji K, Sakaguchi M, Huh NH, Tsuda T, Yamanishi K, Komine M, Iwatsuki K
- Journal Title
  
  J Am Acad Dermatol
  
  Volume: 64 Pages: 879-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] TIRAP, an Adaptor Protein for TLR2/4, Transduces a signal from RAGE Phosphorylated upon Ligand Binding2011
- Author(s)
  Sakaguchi M, Murata M, Yamamoto K, Ono T, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Intraperitoneal administration of an adenovirus vector carrying REIC/Dkk-3 suppresses peritoneal dissemination of scirrhous gastric carcinoma.2011
- Author(s)
  Than SS, Kataoka K, Sakaguchi M, Murata H, Abarzua F, Taketa C, Du G, Yashiro M, Yanagihara K, Nasu Y, Kumon H, Huh NH.
- Journal Title
  
  Oncol Rep. 25
  
  Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] S100A11, a dual growth regulator of epidermal keratinocytes2011
- Author(s)
  Sakaguchi M, Huh NH
- Journal Title
  
  Amino Acids
  
  Volume: 41 Pages: 797-807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Markedly elevated serum levels of calcium-binding S100A8/A9 proteins in psoriatic arthritis are due to activated monocytes/macrophages2011
- Author(s)
  Aochi S, Tsuji K, Sakaguchi M, Huh NH, Tsuda T, Yamanishi K, Komine M, Iwatsuki K
- Journal Title
  
  J Am Acad Dermatol
  
  Volume: 64 Pages: 879-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] S100A11, a dual growth regulator of epidermal keratinocytes2011
- Author(s)
  Sakaguchi M, Huh NH
- Journal Title
  
  Amino Acids
  
  Volume: 41 Pages: 797-807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2011
- Author(s)
  Sakaguchi M, Huh NH, Namba M
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 720 Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma2011
- Author(s)
  Kubo T, Toyooka S, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Ueno T, Muraoka T, Yamamoto H, Nasu Y, Kishimoto T, Pass HI, Matsui H, Huh NH, Miyoshi S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 4965-4974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2011
- Author(s)
  Sakaguchi M, Huh NH, Namba M
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 720 Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis2011
- Author(s)
  Du G, Kataoka K, Sakaguchi M, Abarzua F, Than SS, Sonegawa H, Makino T, Shimizu T, Huh NH
- Journal Title
  
  Exp Dermatol
  
  Volume: 20 Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A New Cytosolic Pathway from a Parkinson's Disease-associated Kinase, BRPK/PINK1 : Activation of Akt via mTORC22011
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami J, Yamada H, Kataoka K, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 7182-7189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis2011
- Author(s)
  Du G, Kataoka K, Sakaguchi M, Abarzua F, Than SS, Sonegawa H, Makino T, Shimizu T, Huh NH
- Journal Title
  
  Exp Dermatol
  
  Volume: 20 Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma2011
- Author(s)
  Kubo T, Toyooka S, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Ueno T, Muraoka T, Yamamoto H, Nasu Y, Kishimoto T, Pass HI, Matsui H, Huh NH, Miyoshi S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 4965-4974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-12011
- Author(s)
  Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 391-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Intraperitoneal administration of an adenovirus vector carrying REIC/Dkk-3 suppresses peritoneal dissemination of scirrhous gastric carcinoma2011
- Author(s)
  Than SS, Kataoka K, Sakaguchi M, Murata H, Abarzua F, Taketa C, Du G, Yashiro M, Yanagihara K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 25 Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] TIRAP, an Adaptor Protein for TLR2/4, Transduces a signal from RAGE Phosphorylated upon Ligand Binding2011
- Author(s)
  Sakaguchi M, Murata M, Yamamoto K, Ono T, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A new cytosolic pathway from a Parkinson's disease-associated kinase, BRPK/PINK1: activation of AKT via MTORC22011
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami JI, Yamada H, Kataoka K, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 7182-7189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A novel tumor suppressor, REIC/Dkk-3 gene identified by our in vitro transformation model of normal human fibroblasts works as a potent therapeutic anti-tumor agent2011
- Author(s)
  Sakaguchi M, Huh NH, Namba M
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 720 Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] A new cytosolic pathway from a Parkinson's disease-associated kinase, BRPK/PINK1 : activation of AKT via MTORC2.2011
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami JI, Yamada H, Kataoka K, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 7182-7189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Intraperitoneal administration of an adenovirus vector carrying REIC/Dkk-3 suppresses peritoneal dissemination of scirrhous gastric carcinoma2011
- Author(s)
  Than SS, Kataoka K, Sakaguchi M, Murata H, Abarzua F, Taketa C, Du G, Yashiro M, Yanagihara K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Oncol Rep
  
  Volume: 25 Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650608
[Journal Article] A new cytosolic pathway from a Parkinson's disease-associated kinase, BRPK/PINK1: activation of AKT via MTORC22011
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami JI, Yamada H, Kataoka K, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 7182-7189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650625
[Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development.2010
- Author(s)
  Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H.
- Journal Title
  
  Int J Oncol. 37(6)
  
  Pages: 1495-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] S100A11, a dual growth regulator of epidermal keratinocytes.2010
- Author(s)
  Sakaguchi M, Huh NH.
- Journal Title
  
  Amino Acids. In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Transcriptional regulation of a brown adipocyte-specific gene, UCP1, by KLF11 and KLF15.2010
- Author(s)
  Yamamoto K, Sakaguchi M, Medina RJ, Niida A, Sakaguchi Y, Miyazaki M, Kataoka K, Huh NH.
- Journal Title
  
  Biochem Biophys Res Commun. 400
  
  Pages: 175-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk-3.2010
- Author(s)
  Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH.
- Journal Title
  
  Int J Cancer. 126(7)
  
  Pages: 1562-1569
- NAID
  120004724432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development.2010
- Author(s)
  Zhangi K, Watanabe M, Kashiwakura Y, Aili S, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H.
- Journal Title
  
  Int J Oncol 37
  
  Pages: 1495-1501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues2010
- Author(s)
  Kataoka K, Sakaguchi M, Peng li K, Taketa C, Yamamoto K, Dui G, Funahashi H, Murata H, Huh NH
- Journal Title
  
  Int J Mol Med
  
  Volume: 26 Pages: 853-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Down-regulation of Bip/Grp78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk32010
- Author(s)
  Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Cancer
  
  Volume: 126 Pages: 1562-1569
- NAID
  120004724432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues2010
- Author(s)
  Kataoka K, Sakaguchi M, Li KP, Taketa C, Yamamoto KI, Du G, Funahashi H, Murata H, Huh NH
- Journal Title
  
  Int J Mol Med
  
  Volume: 26 Pages: 853-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk32010
- Author(s)
  Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Cancer 126
  
  Pages: 15621569-15621569
- NAID
  120004724432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development2010
- Author(s)
  Zhangi K, Watanabe M, Kashiwakura Y, Aili S, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M., Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 1495-1501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Down-regulation of BiP/CRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk32010
- Author(s)
  Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Cancer 126
  
  Pages: 15621569-15621569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk3.2010
- Author(s)
  Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH.
- Journal Title
  
  Int J Cancer. 126
  
  Pages: 1562-1569
- NAID
  120004724432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Transcriptional regulation of a brown adipocyte-specific gene, UCP1, by KLF11 and KLF152010
- Author(s)
  Yamamoto K, Sakaguchi M, Medina RJ, Niida A, Sakaguchi Y, Miyazaki M, Kataoka K, Huh NH
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 175-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues.2010
- Author(s)
  Kataoka K, Sakaguchi M, Peng li K, Taketa C, Yamamoto K, Dui G, Funahashi H, Murata H, Huh NH.
- Journal Title
  
  Int J Mol Med 26
  
  Pages: 853-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Markedly elevated serum levels of calcium-binding S100A8/A9 proteins in psoriatic arthritis are due to activated monocytes/macrophages.2010
- Author(s)
  Aochi S, Tsuji K, Sakaguchi M, Huh NH, Tsuda T, Yamanishi K, Komine M, Iwatsuki K.
- Journal Title
  
  J Am Acad Dermatol. In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk32010
- Author(s)
  Tanimoto R, Sakaguchi M., Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Cancer
  
  Volume: 126 Pages: 1562-1569
- NAID
  120004724432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression.2009
- Author(s)
  Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H.
- Journal Title
  
  Int J Oncol. 34(3)
  
  Pages: 657-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7.2009
- Author(s)
  Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H, Huh NH.
- Journal Title
  
  J Biol Chem. 284(21)
  
  Pages: 14236-14244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells2009
- Author(s)
  Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Int J Mol Med 24
  
  Pages: 789794-789794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells2009
- Author(s)
  Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Int JMol Med
  
  Volume: 24 Pages: 89-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression2009
- Author(s)
  Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Fu tami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H
- Journal Title
  
  Int J Oncol 34
  
  Pages: 657663-657663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of IL-72009
- Author(s)
  Masakiyo Sakaguchi
- Journal Title
  
  J Biol Chem 284
  
  Pages: 12436-12444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] Suppression of carbon tetrachloride-induced liver fibrosis by transplantation of a clonal mesenchymal stem cell line derived from rat bone marrow2009
- Author(s)
  Hardjo M, Miyazaki M, Sakaguchi M, Masaka T, Ibrahim S, Kataoka K, Huh NH
- Journal Title
  
  Cell Transplant 18
  
  Pages: 8999-8999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression2009
- Author(s)
  Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H
- Journal Title
  
  Int J Oncol 34
  
  Pages: 657663-657663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of IL-72009
- Author(s)
  Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  J Biol Chem 284
  
  Pages: 1423614244-1423614244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer.2009
- Author(s)
  Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H, Date H.
- Journal Title
  
  Cancer Gene Ther. 16(1)
  
  Pages: 65-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of IL-72009
- Author(s)
  Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  J Biol Chem 284
  
  Pages: 1423614244-1423614244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] Suppression of carbon tetrachloride-induced liver fibrosis by transplantation of a clonal mesenchymal stem cell line derived from rat hone marrow2009
- Author(s)
  Hardjo M, Miyazaki M, Sakaguchi M, Masaka T, Ibrahim S, Kataoka K, Huh NH
- Journal Title
  
  Cell Transplant 18
  
  Pages: 8999-8999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] REIC/Dkk-3 stable transfection reducesthe malignant phenotype of mouse prostate cancer RM9 cells2009
- Author(s)
  Chen J, Watanabe H, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H
- Journal Title
  
  Int J Mol Med 24
  
  Pages: 789794-789794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of IL-72009
- Author(s)
  Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 14236-14244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591699
[Journal Article] REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer2009
- Author(s)
  Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H, Date H
- Journal Title
  
  Cancer Gene Ther 16
  
  Pages: 6572-6572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015031
[Journal Article] REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer2009
- Author(s)
  Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H, Date H
- Journal Title
  
  Cancer Gene Ther 16
  
  Pages: 6572-6572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689011
[Journal Article] REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells.2009
- Author(s)
  Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H.
- Journal Title
  
  Int J Mol Med. 24(6)
  
  Pages: 789-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] S100All, an Dual Mediator for Growth Regulation of Human Kerationocytes.2008
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  Molecular Biology of the Cell 19
  
  Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013035
[Journal Article] N-h.Mechanistic Analysis of Resistance to REIC/Dkk-3-induced Apoptosis in Human Bladder Cancer Cells2008
- Author(s)
  Kobayashi, T., Sakaguchi M., Tanimoto R., Abarzua, F., Takaishi M., Kaku, H. Kataoka, , K., Saika T.,Nasu Y., Miyazaki M., Kumon H., Huh
- Journal Title
  
  Acta Med Okayama 62
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] An N-terminal 78 amino acid truncation of REIC/Dkk-3 effectively induces apoptosis.2008
- Author(s)
  Abarzua F, Kashiwakura Y, Takaoka M, Watanabe M, Ochiai K, Sakaguchi M, Iwawaki T, Tanimoto R, Nasu Y, Huh NH, Kumon H.
- Journal Title
  
  Biochem Biophys Res Commun. 375(4)
  
  Pages: 614-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] S100A11, an dual mediator for growth regulation of human keratinocytes2008
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  Mol Biol Cell 19・1
  
  Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591249
[Journal Article] Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis.2008
- Author(s)
  Kashiwakura Y, Ochiai K, Watanabe M, Abarzua F, Sakaguchi M, Takaoka M, Tanimoto R, Nasu Y, Huh NH, Kumon H.
- Journal Title
  
  Cancer Res. 68(20)
  
  Pages: 8333-8341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] S100A11, a Dual Mediator for Growth Regulation of Human Keratinocytes2008
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 78-85
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591249
[Journal Article] Mechanistic analysis of resistance to REIC/Dkk-3-induced apoptosis in human bladder cancer cells.2008
- Author(s)
  Kobayashi T, Sakaguchi M, Tanimoto R, Abarzua F, Takaishi M, Kaku H, Kataoka K, Saika T, Nasu Y, Miyazaki M, Kumon H, Huh NH.
- Journal Title
  
  Acta Med Okayama. 62(6)
  
  Pages: 393-401
- NAID
  120002304961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390426
[Journal Article] REIC/Dkk-3overexpression downregulates P-glycoprotein in multidrug-resistant MCF7 /ADR cells and induces apoptosis in breast cancer2008
- Author(s)
  Kawasaki K., Watanabe M., Sakaguchi M., Ogasawara Y., Ochiai K., Nasu Y., Doihara H., Kashiwakura Y., Huh N-h., Kumon H., Date H.
- Journal Title
  
  Cancer Gene Therapy 16
  
  Pages: 65-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] An N-terminal 78 amino acid truncation of REIC/Dkk-3 effectively induces apoptosis2008
- Author(s)
  Abarzua F., Kashiwakura Y., Takaoka M., Watanabe M., Ochiai K., Sakaguchi M., Iwawaki T., Tanimoto R., Nasu Y., Huh NH., Kumon H.
- Journal Title
  
  Biochem Biophys Res Commun 375
  
  Pages: 614-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Isolation of a bone marrow-derived stem cell line with high proliferation potential and its application for preventing acute fatal liver failure.2007
- Author(s)
  Miyazaki M, Hardjo M, Masaka T, Tomiyama K, Mahmut N, Medina RJ, Niida A, Sonegawa H, Du G, Yong R, Takaishi M, Sakaguchi M, Huh NH
- Journal Title
  
  Stem Cells(reviewed paper) 25
  
  Pages: 2855-2863
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Journal Article] Truncation of annexin Al is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells.2007
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 35679-35686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013035
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumo growth and metastasis in an orthotopic prostate cancer model2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H
- Journal Title
  
  Cancer Gene Ther. 14
  
  Pages: 765-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007
- Author(s)
  Tanimoto R. Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med 19
  
  Pages: 363-368
- NAID
  10019918537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Truncation of annexin Al is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells2007
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  J Biol Chem 282・49
  
  Pages: 35679-35686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591249
[Journal Article] Involvement of deterioration in S100C/A11-mediated pathway in resistance of human squamous cancer cell lines to TGFβ-induced growth suppression.2007
- Author(s)
  Sonegawa H, Nukui T, Li DW, Takaishi M, Sakaguchi M, Huh NH
- Journal Title
  
  J Mol Med (In Press)
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007
- Author(s)
  Tanimoto R, Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med. 19
  
  Pages: 363-368
- NAID
  10019918537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007
- Author(s)
  Abarzua F, Sakaguchi M, Tanimoto R, Sonegawa H, Li DW, Edamura K, Kobayashi T, Watanabe M, Kashiwakura Y, Kaku H, Saika T, Nakamura K, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med. 20
  
  Pages: 37-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] Truncation of annexin A1 is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells2007
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 35679-35686
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591249
[Journal Article] Truncation of annexin Al is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells2007
- Author(s)
  Sakaguchi, et. al.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 35679-35686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591249
[Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model2007
- Author(s)
  Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh N.H. Kumon H
- Journal Title
  
  Cancer Gene Ther 14
  
  Pages: 765-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390437
[Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer.2006
- Author(s)
  Tanimoto R, Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH
- Journal Title
  
  Int J Mol Med 19
  
  Pages: 363-368
- NAID
  10019918537
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Denatured and Reversibly Cationized p53 Readily Enters Cells and Simultaneously Folds to the Functional Protein in the Cells.2006
- Author(s)
  Murata H, Sakaguchi M, Futami J, Kitazoe M, Maeda T, Doura H, Kosaka M, Tada H, Seno M, Huh NH, Yamada H
- Journal Title
  
  BIOCHEMISTRY-US 45
  
  Pages: 6124-6132
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of JNK2005
- Author(s)
  Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kurose K, Ebara S, Miyazaki M, Namba M, Kumon H, Huh NH
- Journal Title
  
  Cancer Research 65
  
  Pages: 9617-9622
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Protein Transduction Assisted by Polyethylenimine-Cationized Carrier Proteins2005
- Author(s)
  Kitazoe M, Murata H, Futami J, Maeda T, Sakaguchi M, Miyazaki M, Kosaka M, Tada H, Seno M, Huh NH, Namba M, Nishikawa M, Maeda Y, Yamada H
- Journal Title
  
  Journal of Biochemistry 137
  
  Pages: 693-701
- NAID
  10017345558
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Intracellular Delivery of Proteins into Mammalian Living Cells by Polyethylenimine-Cationization2005
- Author(s)
  Futami J, Kitazoe M, Maeda T, Nukui F, Sakaguchi M, Kosaka J, Miyazaki M, Kosaka M, Tada H, Seno M, Sasaki J, Huh N-H, Namba M, Yamada H
- Journal Title
  
  Journal of Bioscience and Bioengineering 99
  
  Pages: 95-103
- NAID
  110002695633
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei.2005
- Author(s)
  Sakaguchi et al.
- Journal Title
  
  Nucleic Acids Research 33
- Data Source
  KAKENHI-PROJECT-17014065
[Journal Article] Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei2005
- Author(s)
  Sakaguchi M, Nukui T, Sonegawa H, Murata H, Futami J, Yamada H, Huh NH
- Journal Title
  
  Nucleic Acids Research 33:e88
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] Bifurcated converging pathways for high Ca2+- and TGFbeta-induced inhibition of growth of normal human keratinocytes.2005
- Author(s)
  Sakaguchi et al.
- Journal Title
  
  Proceedings of National Academy of Science, U.S.A. 102
  
  Pages: 13921-13926
- Data Source
  KAKENHI-PROJECT-17014065
[Journal Article] Bifurcated converging pathways for high Ca^<++>- and TGFb-induced inhibition of growth of normal human keratinocytes2005
- Author(s)
  Sakaguchi M, Sonegawa H, Nukui T, Sakaguchi Y, Miyazaki M, Namba M, Huh NH.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 102
  
  Pages: 13921-13926
- Data Source
  KAKENHI-PROJECT-17790150
[Journal Article] PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11.2004
- Author(s)
  Sakaguchi et al.
- Journal Title
  
  Journal of Cell Biology 164(7)
  
  Pages: 979-984
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorvlation of S100C/A11.2004
- Author(s)
  Sakaguchi et al.
- Journal Title
  
  Journal of Cell Biology 164(7)
  
  Pages: 979-984
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] Introduction of an N-terminal peptide of S100C/A11 into human cells induces apoptotic cell death.2004
- Author(s)
  Makino E, Sakaguchi M, Iwatsuki K, Huh NH
- Journal Title
  
  J Mol Med. 82(9)
  
  Pages: 612-620
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11.2004
- Author(s)
  Sakaguchi M, Miyazaki M, Sonegawa H, Kashiwagi M, Ohba M, Kuroki T, Namba M, Huh NH
- Journal Title
  
  J Cell Biol. 164(7)
  
  Pages: 979-984
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] S100C/A11 is a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytes.2003
- Author(s)
  Sakaguchi M, Miyazaki M, Takaishi M, Sakaguchi Y, Makino E, Kataoka N, Yamada H, Namba M, Huh NH
- Journal Title
  
  J Cell Biol. 163(4)
  
  Pages: 825-835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] S100C/A11 Is a Key Mediator of Ca^<++>-induced Growth Inhibition of Human Epidermal Keratinocytes.2003
- Author(s)
  Sakaguchi et al.
- Journal Title
  
  Journal of Cell Biology 163(4)
  
  Pages: 825-835
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] Expression pattern of REIC/Dkk-3 in mouse squamous epithelia
- Author(s)
  Kataoka K, Du G, Maehara N, Murata H, Sakaguchi M, Huh N
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591699
[Patent] ANTIBODY-DRUG CONJUGATES AND USE OF ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] USE OF ANTIBODY-DRUG CONJUGATES AND ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] USE OF ANTIBODY-DRUG CONJUGATES AND ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 化合物、神経系疾患の予防又は治療薬2021
- Inventor(s)
  村田等、阪口政清、安藤　隆幸、福田　達也、中村　仁
- Industrial Property Rights Holder
  村田等、阪口政清、安藤　隆幸、福田　達也、中村　仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-135934
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K07369
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2020
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 肺炎症性疾患の予防及び/又は治療剤2019
- Inventor(s)
  阪口政清、豊岡伸一、木下理恵、荒木恒太
- Industrial Property Rights Holder
  岡山大学、新潟大学、群馬大学、川崎学園
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-197222
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H03577
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2019
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-228542
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 抗S100A8/A9抗体とその用途2019
- Inventor(s)
  阪口政清、豊岡伸一、冨田秀太、枝園和彦、木下理恵　他
- Industrial Property Rights Holder
  岡山大学、新潟大学、群馬大学、川崎学園
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03577
[Patent] 炎症性肺疾患の予防及び／又は治療剤2019
- Inventor(s)
  阪口政清、豊岡伸一、木下理恵、荒木恒太
- Industrial Property Rights Holder
  国立大学法人岡山大学　新潟大学　群馬大学　学校法人川崎学園
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03746
[Patent] 抗S100A8/A9抗体2018
- Inventor(s)
  阪口政清、豊岡伸一　他
- Industrial Property Rights Holder
  岡山大学他
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H03577
[Patent] 遺伝子発現用カセット及びその産生物2018
- Inventor(s)
  阪口政清，西堀正洋，公文裕巳，村田等，山本健一，木下理恵
- Industrial Property Rights Holder
  阪口政清，西堀正洋，公文裕巳，村田等，山本健一，木下理恵
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03577
[Patent] 遺伝子発現用カセット及びその産生物2016
- Inventor(s)
  阪口政清、西堀正洋、村田　等、山本健一、木下理恵
- Industrial Property Rights Holder
  国立大学法人　岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-26290039
[Patent] 遺伝子発現用カセット及びその産生物2016
- Inventor(s)
  阪口政清、西堀正洋、村田　等、山本健一、木下理恵
- Industrial Property Rights Holder
  国立大学法人　岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-15K14382
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2016
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、他、阪口政清
- Industrial Property Rights Holder
  国立大学法人　岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-14
- Acquisition Date
  2016-11-29
- Overseas
- Data Source
  KAKENHI-PROJECT-15K14382
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2016
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、他、阪口政清
- Industrial Property Rights Holder
  国立大学法人　岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-14
- Acquisition Date
  2016-11-29
- Overseas
- Data Source
  KAKENHI-PROJECT-26290039
[Patent] 遺伝子発現用カセット及びその産生物2015
- Inventor(s)
  阪口政清、西堀正洋、公文裕巳、村田等、山本健一、木下理恵
- Industrial Property Rights Holder
  阪口政清、西堀正洋、公文裕巳、村田等、山本健一、木下理恵
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-198160
- Filing Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-15K14382
[Patent] 遺伝子発現用カセット及びその産生物2015
- Inventor(s)
  阪口政清、西堀正洋、公文裕巳、村田等、山本健一、木下理恵
- Industrial Property Rights Holder
  阪口政清、西堀正洋、公文裕巳、村田等、山本健一、木下理恵
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-198160
- Filing Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-26290039
[Patent] PINK1のユビキチンアッセイ及びスクリーニングへの利用2012
- Inventor(s)
  村田　等、阪口政清、許南浩
- Industrial Property Rights Holder
  村田　等、阪口政清、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-165160
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PUBLICLY-24117711
[Patent] PINK1のユビキチンアッセイ及びスクリーニングへの利用2012
- Inventor(s)
  村田等、阪口政清、許南浩
- Industrial Property Rights Holder
  村田等、阪口政清、許南浩
- Industrial Property Number
  2012-165160
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23650625
[Patent] アデノウイルスベクターをがん細胞に対して選択的に導入可能なポリペプチドおよび当該ポリペプチドを備えるアデノウイルスベクター2012
- Inventor(s)
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Rights Holder
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Number
  2012-085969
- Filing Date
  2012-04-04
- Data Source
  KAKENHI-PROJECT-23650625
[Patent] ＮＰＴＮβとＳ１００Ａ８の結合の阻害を指標とする細胞増殖抑制剤のスクリーニング方法2012
- Inventor(s)
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Holder
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-204279
- Filing Date
  2012-09-18
- Data Source
  KAKENHI-PUBLICLY-24117711
[Patent] アデノウイルスベクターをがん細胞に対して選択的に導入可能なポリペプチドおよび当該ポリペプチドを備えるアデノウイルスベクター2012
- Inventor(s)
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Rights Holder
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-085969
- Filing Date
  2012-04-04
- Data Source
  KAKENHI-PUBLICLY-24117711
[Patent] NPTNβとS100A8の結合の阻害を指標とする細胞増殖抑制剤のスクリーニング方法2012
- Inventor(s)
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Holder
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Number
  2012-204279
- Filing Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23650608
[Patent] PINK1のユビキチンアッセイ及びスクリーニングへの利用2012
- Inventor(s)
  村田　等、阪口政清、許南浩
- Industrial Property Rights Holder
  村田　等、阪口政清、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-165160
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23650625
[Patent] NPTNβとS100A8の結合の阻害を指標とする細胞増殖抑制剤のスクリーニング方法2012
- Inventor(s)
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Holder
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Number
  2012-204279
- Filing Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23650625
[Patent] ＮＰＴＮβとＳ１００Ａ８の結合の阻害を指標とする細胞増殖抑制剤のスクリーニング方法2012
- Inventor(s)
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Holder
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-204279
- Filing Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23650625
[Patent] ＮＰＴＮβとＳ１００Ａ８の結合の阻害を指標とする細胞増殖抑制剤のスクリーニング方法2012
- Inventor(s)
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Holder
  阪口政清、日比野利彦、山本真実、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-204279
- Filing Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23650608
[Patent] アデノウイルスベクターをがん細胞に対して選択的に導入可能なポリペプチドおよび当該ポリペプチドを備えるアデノウイルスベクター2012
- Inventor(s)
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Rights Holder
  阪口政清、近藤英作、許南浩、手塚克成
- Industrial Property Number
  2012-085969
- Filing Date
  2012-04-04
- Data Source
  KAKENHI-PROJECT-23650608
[Patent] PINK1のユビキチンアッセイ及びスクリーニングへの利用2012
- Inventor(s)
  村田　等、阪口政清、許南浩
- Industrial Property Rights Holder
  村田　等、阪口政清、許南浩
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-165160
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23650608
[Patent] PINK1のユビキチンアッセイ及びスクリーニングへの利用2012
- Inventor(s)
  村田等、阪口政清、許南浩
- Industrial Property Rights Holder
  村田等、阪口政清、許南浩
- Industrial Property Number
  2012-165160
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23650608
[Patent] REIC発現アデノウイルスベクター2011
- Inventor(s)
  渡部昌実, 公文裕巳, 許南浩, 阪口政清
- Industrial Property Rights Holder
  岡山大学, 桃太郎源(株)
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-117321
- Filing Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23390382
[Patent] 遺伝子発現を上昇させるシステム及ぴ該システムを保持したべクター2009
- Inventor(s)
  阪口政清、公文裕巳、許南浩、渡邉昌美
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-264299
- Filing Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-20015031
[Patent] 遺伝子発現を上昇させるシステム及び該システムを保持したベクター2009
- Inventor(s)
  阪口政清、公文裕巳、許南浩、渡邉昌美
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-264299
- Filing Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-21689011
[Patent] 遺伝子発現を上昇させるシステム及び該システムを保持したベクター2009
- Inventor(s)
  阪口政清、公文裕巳、許南浩、渡部昌実
- Industrial Property Rights Holder
  桃太郎源社
- Industrial Property Number
  2009-264299
- Filing Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-21689011
[Patent] 遺伝子発現を上昇させるシステム及び該システムを保持したベクター2009
- Inventor(s)
  公文裕巳、許南浩、阪口政清、渡部昌実
- Industrial Property Rights Holder
  岡山大学、桃太郎源(株)
- Filing Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-20390426
[Presentation] 膵がん進展におけるS100A8/A9 の機能解析と抗体による治療への応用2023
- Author(s)
  宮本航大, 木下理恵, 小林和子, 友信奈保子, 山本健一, 村田等, 許南浩, 豊岡伸一, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K06717
[Presentation] REIC タンパク質によるPD-L1 制御を介した抗腫瘍機序の解明2023
- Author(s)
  合原勇馬, 友信奈保子, 木下理恵, 村田等, 山本健一, 難波正義, 許南浩, 公文裕己, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 血漿タンパク受容体をターゲットとした創薬プラン2023
- Author(s)
  阪口政清
- Organizer
  第 44 回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 核内 PD-L1 は MCRIP1 を抑制することでトリプルネガティブ乳がん細胞の浸潤能を促進する2023
- Author(s)
  合原勇馬、友信奈保子、木下理恵、山本建一、村田等、阪口政清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] STAT1/3シグナル経路によるNAD+代謝酵素制御を介した神経軸索変性と細胞死の抑制2023
- Author(s)
  安井　優, 村田　等, 大磯　和真, 越智　俊樹, 友信　奈保子, 山本　健一, 木下　理恵, 阪口　政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-22K06884
[Presentation] A tremendous therapeutic benefit of targeting strategy of S100A8/A9 on metastatic prevention of cancers2023
- Author(s)
  Masakiyo Sakaguchi
- Organizer
  The annual meeting hepatobiliary of Hunan -2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 糞便微生物移植治療から見出した腸内の放線菌の生理活性評価2023
- Author(s)
  阪口義彦, 武晃, 後藤和義, 原正也, 友信奈保子, 山本健一, 菊池雄太, 坂本光央, 加藤はる, 大宮直木, 阪口政清, 永浜政博
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] STAT1/3 シグナル経路によるNAD+代謝酵素制御を介した神経軸索変性と細胞死の抑制2023
- Author(s)
  安井優, 村田等, 大磯和真, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 膵がん進展におけるS100A8/A9 の機能解析と抗体による治療への応用2023
- Author(s)
  宮本航大, 木下理恵, 小林和子, 友信奈保子, 山本健一, 村田等, 許南浩, 豊岡伸一, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] ヒトiPS 細胞由来神経細胞と動物モデルを用いた軸索変性誘導分子SARM1 の阻害剤開発2023
- Author(s)
  村田等, 安藤隆幸, 安井優, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] STAT1/3シグナル経路によるNAD+代謝酵素制御を介した軸索変性と神経細胞死の抑制2023
- Author(s)
  村田; 等、安井優、越智俊樹、友信奈保子、山本健一、木下理恵、阪口政清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] ヒトメラノーマ細胞の増殖と血管新生における冬虫夏草の抗腫瘍作用評価2023
- Author(s)
  長﨑直也, 堀井聡, I Wayan Sumardika, I Made Winarsa Ruma, 友信奈保子, 木下理恵, 山本健一, 村田等, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] β3 インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発2023
- Author(s)
  久保美代子、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 膀胱がんの進行における S100A8/A9 に関わる分子機構の解明2023
- Author(s)
  友信奈保子、木下理恵、合原勇馬、Yoni Komalasari、二見淳一郎、山内明、近藤英作、豊岡伸一、阪口政清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 膵がん進展における S100A8/A9 の役割解明と治療方法の開発2023
- Author(s)
  木下理恵、友信奈保子、山内明、二見淳一郎、豊岡伸一、阪口政清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] TLR4 accelerates bladder cancer progression upon interaction with S100A8/A92023
- Author(s)
  Fan Jiang,Acosta Gonzalez Herik Rodrigo, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Ni Luh Gede Yoni Komalasari, Ken-ichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Shinichi Toyooka, Masami Watanabe, Yasutomo Nasu, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that targets the cell-surface annexin A22023
- Author(s)
  Yoni Komalasari, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Kenichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Futoshi Kuribayashi, Yusuke Inoue, Shinichi Toyooka , Masakiyo Sakaguchi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] Development of pancreatic cancer therapy targeting S100A8/A9 of tumor microenvironment2023
- Author(s)
  Rie Kinoshita, Nahoko Tomonobu, Akira Yamauchi, Junichiro Futami, Shinichi Toyooka, Masakiyo Sakaguch
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06717
[Presentation] ヒトiPS細胞由来神経細胞と動物モデルを用いた軸索変性誘導分子SARM1の阻害剤開発2023
- Author(s)
  村田　等, 安藤　隆幸, 安井　優, 越智　俊樹, 友信　奈保子, 山本　健一, 木下　理恵, 阪口　政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-22K06884
[Presentation] The novel compound 14-100 and its analogues were discovered in Cell-based Drug Discovery approach2023
- Author(s)
  Akira Yamauchi, Shuichiro Okamoto, Tominari Choshi, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, Masahiro Yamamura
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明2023
- Author(s)
  友信奈保子, 木下理恵, 合原勇馬, Ni Luh Gede Yoni Komalasari, Fan Jiang, 村田等, 山本健一, 山内明, 近藤英作, 豊岡伸一, 西堀正洋, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 癌転移抑制を目指した細胞動態解析と創薬2023
- Author(s)
  山内明 ,町支臣成, 岡本秀一郎, 片瀬直樹, 山村真弘, 友信奈保子, 木下理恵, 阪口政清, 栗林太
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 亜鉛結合により活性化されるZEB1 転写因子の乳がん進展における意義の解明2023
- Author(s)
  山本健一, 平林大輔, 丸山顕嘉, 友信奈保子, 木下理恵, Ni Luh Gade Yoni Komalasari, 村田等, 合原勇馬, 江帆, 山内明, 栗林太, 豊岡伸一, 井上裕介, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] Suppression of axon degeneration and neuronal cell death by STAT1/3 signaling through regulation of NAD+-biosynthetic and consuming enzyme2023
- Author(s)
  村田　等, 安井　優, 越智　俊樹, 友信　奈保子, 山本　健一, 木下　理恵, 阪口　政清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06884
[Presentation] 細胞表面アネキシンA2/S100A11 結合に着目した乳がん進行の機序解明2023
- Author(s)
  髙橋徹多, 友信奈保子,Ni LuhGede Yoni Komalasari, 合原勇馬, 山本健一, 木下理恵, 村田等, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 軸索変性誘導分子 SARM1の阻害剤開発2022
- Author(s)
  村田等、安藤隆幸、大磯和真、友信奈保子、山本健一、木下理恵、阪口政清
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20K07636
[Presentation] 軸索変性誘導分子 SARM1の阻害剤開発2022
- Author(s)
  村田等、安藤隆幸、大磯和真、友信奈保子、山本健一、木下理恵、阪口政清
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-22K06884
[Presentation] 細胞動態アッセイデバイス TAXIScan で見出された化合物は腫瘍増大と転移の両方を抑える2022
- Author(s)
  山内明、山村真弘、片瀬直樹、友信奈保子、木下理恵、阪口政清、岡本秀一郎
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] REIC protein suppresses tumor progression through PD-L1 regulation in cancer cells2022
- Author(s)
  Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Hitoshi Murata, Ken-ichi Yamamoto, Masayoshi Namba, Nam-ho Huh, Hiromi Kumon, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20K07636
[Presentation] Lysyl oxidase-like 4 is prominent in breast cancer progression through its en]ymatic activities2022
- Author(s)
  Ni Luh Gede Yoni Komalasari, Nahoko Tomonobu, Fan Jiang, Acosta Gonzalez Herik Rodrigo, Yuma Gohara, Ken-ichi Yamamoto, Rie Kinoshita, Hitoshi Murata, Yusuke Inoue, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 肺腺癌におけるSpred2の発現と増殖・浸潤の関係2022
- Author(s)
  Yoko Ota, Gao Tong, Sumardika I Wayan, Masayoshi Fujisawa, Teizo Yoshimura, Masakiyo Sakaguchi and Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] HRG によるメラノーマの S100A8/A9 を介した脳指向性転移抑制効果の検討2022
- Author(s)
  友信奈保子、Yoni Komalasari、合原勇馬、木下理恵、山本健一、山内明、近藤英作、豊岡伸一、阪口政清
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 軸索変性誘導分子 SARM1の阻害剤開発2022
- Author(s)
  村田等、安藤隆幸、大磯和真、友信奈保子、山本健一、木下理恵、阪口政清
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 肺腺癌におけるSpred2の発現と増殖・浸潤の関係2022
- Author(s)
  Yoko Ota, Gao Tong, Sumardika I Wayan, Masayoshi Fujisawa, Teizo Yoshimura, Masakiyo Sakaguchi, Akihiro Matsukawa
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] 炎症性疾患に対する抗S100A8/A9抗体療法におけるマクロファージの役割2022
- Author(s)
  木下理恵、小林和子、荒木恒太、佐藤博紀、友信奈保子、村田等、許南浩、豊岡伸一、阪口政清
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20K07636
[Presentation] REIC protein suppresses tumor progression through PD-L1 regulation in cancer cells2022
- Author(s)
  Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Hitoshi Murata, Ken-ichi Yamamoto, Masayoshi Namba, Nam-ho Huh, Hiromi Kumon, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] REIC/Dkk-3の受容体への結合はトリプルネガティブ乳がんのPD-L1の発現を抑制する2022
- Author(s)
  吉澤智香子,合原勇馬,友信奈保子,木下理恵,二見淳一郎,村田等山本健一,阪口政清
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] REIC/Dkk-3の受容体への結合はトリプルネガティブ乳がんのPD-L1の発現を抑制する2022
- Author(s)
  吉澤智香子、合原勇馬、友信奈保子、木下理恵、二見淳一郎、村田等、山本健一、阪口政清
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07636
[Presentation] がん転移におけるS100A8/A9の機能解明とその制御　ーHRGの発見による新展開ー2022
- Author(s)
  阪口政清
- Organizer
  日本血液製剤機構中央研究所基礎研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 腫瘍微小環境を悪性化する S100A8/A9 を標的としたがん治療薬の開発2022
- Author(s)
  木下理恵、友信奈保子、山内明、二見淳一郎、近藤英作、豊岡伸一、阪口政清
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07636
[Presentation] REIC タンパク質による免疫チェックポイント制御機構の解明2022
- Author(s)
  合原勇馬、友信奈保子、木下理恵、山本健一、阪口政清
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 炎症性疾患に対する抗S100A8/A9抗体療法におけるマクロファージの役割2022
- Author(s)
  木下理恵、小林和子、荒木恒太、佐藤博紀、友信奈保子、村田等、許南浩、豊岡伸一、阪口政清
- Organizer
  日本組織培養学会第94回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 腫瘍微小環境を悪性化する S100A8/A9 を標的としたがん治療薬の開発2022
- Author(s)
  木下理恵、友信奈保子、山内明、二見淳一郎、近藤英作、豊岡伸一、阪口政清
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] S100A8/A9-NPTNb シグナルによる肺がん転移メカニズムの解析2022
- Author(s)
  山本健一;友信奈保子;木下理恵;二見淳一郎;山内明;豊岡伸一;近藤栄作;阪口政清
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 血管内皮細胞におけるHMGB1の動態と修飾抗HMGB1mAbを用いたDDSがん治療2021
- Author(s)
  西堀正洋, 高尚澤, 友信奈保子, 阪口政清
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] キシリトールのグルタチオン制御を介したがん選択的抗がん作用の解析2021
- Author(s)
  友信奈保子、合原勇馬、木下理恵、阪口政清
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 肺腺癌におけるSpred2の発現の検討と増殖、浸潤との関連2021
- Author(s)
  太田陽子、藤澤真義、吉村禎造、IWayan Ｓ、しえん和彦、阪口政清、豊岡伸一、松川昭博
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02988
[Presentation] キシリトールの細胞内グルタチオン調節によるがん選択的細胞死誘導機序の解明2021
- Author(s)
  友信奈保子，木下理恵，山本健一，村田等，阪口政清
- Organizer
  日本組織培養学会第93回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] がんの転移制御を目指して2021
- Author(s)
  阪口政清
- Organizer
  岡山肺癌基礎研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] Synergistic Regulation of Hepatic Fsp27b Expression by HNF4α and CREBH2021
- Author(s)
  Carlos Ichiro Kasano-Camones, Masayuki Takizawa, Wakana Iwasaki, Shota Sasaki, Mume Hamada, Aoi Morimoto, Masakiyo Sakaguchi, Frank J. Gonzalez, Yusuke Inoue
- Organizer
  Asian Pacific Association for the Study of Liver(APASL) Single Topic Conference Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] 疾患特異的iPS細胞と動物モデルを用いたパーキンソン病における軸索変性誘導分子SARM1のリン酸化制御解析2021
- Author(s)
  村田等、越智俊樹、友信奈保子、山本健一、木下理恵、阪口政清
- Organizer
  第93回日本組織培養学会
- Data Source
  KAKENHI-PROJECT-19K07369
[Presentation] 培養肝細胞を用いたプラスチックラップによる細胞傷害性の解析2021
- Author(s)
  山本健一 , Xian Wen Tan , 有元佐賀恵 , 押木俊之 , 難波正義 , 阪口政清
- Organizer
  日本組織培養学会第93回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 疾患特異的iPS細胞と動物モデルを用いたパーキンソン病における軸索変性誘導分子 SARM1のリン酸化制御解析2021
- Author(s)
  村田等, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清
- Organizer
  日本組織培養学会第93回大会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] ロテノン誘発パーキンソニズムの病態形成におけるSARM1リン酸化制御の意義2020
- Author(s)
  村田等、越智俊樹、山本健一、木下理恵、阪口政清
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07369
[Presentation] 6.分泌性S100A11は膵臓癌の細胞運動性を高める腫瘍周囲の線維芽細胞を活性化する2020
- Author(s)
  合原勇馬, 光井洋介, 友信奈保子, 木下理恵, 山本健一, 山内明, 山村真弘, 近藤英作, 豊岡伸一, 那須保友, 村田等, 阪口政清
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 細胞外S100A11 によりがん間質線維芽細胞が加速する膵がん進展のメカニズムの解明2020
- Author(s)
  合原勇馬, 光井洋介, 友信奈保子, 木下理恵, 山内明, 山村真弘, 近藤英作, 豊岡伸一, 那須保友 ,阪口政清
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 細胞外 S100A11 によりがん間質線維芽細胞が加速する膵がん進展のメカニズムの解明2020
- Author(s)
  合原勇馬、光井洋介、友信奈保子、木下理恵、山内明、山村真弘、近藤英作、豊岡伸一、那須保友、阪口政清
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03527
[Presentation] HNF4AとCREBHによる肝臓CIDEC2/Fsp27bの相乗的な発現制御2020
- Author(s)
  笠野一郎、瀧澤将行、岩﨑若菜、佐々木翔太、濱田夢芽、守本葵、阪口政清、Frank J. Gonzalez、井上裕介
- Organizer
  令和2年度日本化学会関東支部群馬地区研究交流発表会
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] 5.ロテノン誘発パーキンソニズムの病態形成におけるSARM1リン酸化制御の意義2020
- Author(s)
  村田等, 越智俊樹, 山本健一, 木下理恵, 阪口政清
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 阻害は食道扁平上皮癌において細胞増殖だけでなく走化性も抑制する2020
- Author(s)
  山村真弘, 山内明, 片瀬直樹, 岡本秀一郎 ,阪口政清, 山口佳之
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] 分泌性S100A11は膵臓癌の細胞運動性を高める腫瘍周囲の繊維芽細胞を活性化する2020
- Author(s)
  合原勇馬、光井洋介、友信奈保子、木下理恵、山本健一、山内明、山村真弘、近藤英作、豊岡伸一、那須保友、村田等、阪口政清
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07369
[Presentation] HNF4AとCREBHによる肝臓CIDE2/Fsp27bの相乗的な発現制御2020
- Author(s)
  笠野一郎、瀧澤将行、岩﨑若菜、佐々木翔太、濱田夢芽、守本葵、阪口政清、Frank J Gonzalez、井上裕介
- Organizer
  第19回生体機能研究会
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] HNF4γ2に相互作用するタンパク質の探索2020
- Author(s)
  江原伸哉, 佐々木翔太, 浦部瑞穂 ,前田つかさ, 鈴木淳子, 入江亮太, 鈴木正則, 外丸靖浩, 阪口政清, FRANK Gonzalez J.,井上裕介
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells.2020
- Author(s)
  Akira Yamauchi, Masahiro Yamamura, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, and Shuichiro Okamoto
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] キシリトールによるがん細胞選択的抗がん作用の分子機構の解明ならびにキシリトールの生体における抗がん効能の検討2020
- Author(s)
  友信奈保子, 合原勇馬, 木下理恵, 阪口政清
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] HNF4αとCREBHによる肝臓のFsp27bの相乗的な発現制御2020
- Author(s)
  笠野一郎, 瀧澤将行, 岩崎若菜, 佐々木翔太, 濱田夢芽, 守本葵, 阪口政清, GONZALEZ Frank J., 井上裕介
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] HNF4αとCREBHによる肝臓のFsp27bの相乗的な発現制御2020
- Author(s)
  笠野一郎、瀧澤将行、岩崎若菜、佐々木翔太、濱田夢芽、守本葵、阪口政清、Frank Gonzalez、井上裕介
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] リンパ内皮細胞上のNOX4 は癌細胞のリンパ系への遊走に重要な役割を果たす2020
- Author(s)
  山内明, 山村真弘, 片瀬直樹, 友信奈保子, 木下理恵, 阪口政清, 岡本秀一郎
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03516
[Presentation] HNF4γ2に相互作用するタンパク質の探索2020
- Author(s)
  江原伸哉、佐々木翔太、浦部瑞穂、前田つかさ、鈴木淳子、入江亮太、鈴木正則、外丸靖浩、阪口政清、Gonzalez Frank、井上裕介
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Gao S, Wake H, Sakaguchi M, Wang D, Mori S, Liu K, Teshigawara K, Gao Y, Takahashi H, Nishibori M.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 肺腺がん細胞における核内受容体HNF4αの機能解析と標的遺伝子の同定2019
- Author(s)
  亀井めぐみ、濱田真輝、阪口政清、井上裕介
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07474
[Presentation] Regulation of SARM1-NAD+ cleavage activity and mitochondrial function through phosphorylation by JNK2019
- Author(s)
  村田等、山本健一、木下理恵、阪口政清
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PROJECT-19K07369
[Presentation] JNKによるリン酸化を介したSARM1のNAD+代謝と軸索変性への寄与2019
- Author(s)
  村田等、阪口政清
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07369
[Presentation] Prevention of Aging Process: Biomolecular insight, Specific title: A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2019
- Author(s)
  Masakiyo Sakaguchi
- Organizer
  National Symposium and Workshop in Anti-Aging Medicine (NASWAAM)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Novel therapeutic approach based on S100A8/A9-mediated organ tropic cancer metastasis.2019
- Author(s)
  Kinoshita R, Tomonobu N, Yamauchi A, Shien K, Tomida S, Murata H, Futami J, Kondo E, Toyooka S, Sakaguchi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] 超高効率遺伝子発現ベクターの開発とその応用2019
- Author(s)
  阪口政清
- Organizer
  資生堂特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Novel biologics to prevent cancer metastasis,2019
- Author(s)
  Masakiyo Sakaguchi
- Organizer
  The 9th International DAMPs and Alarmins Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Doublecortin-like Kinase 1 (DCLK1) correlates with the cell proliferation in malignant pleural mesothelioma2019
- Author(s)
  Akihiro Miura, Hiromasa Yamamoto, Hiroyuki Tao, Ken Suzawa, Shunsaku Miyauchi, Kota Araki, Yuta Takahashi, Eisuke Kurihara, Yusuke Ogoshi, Kazuhiko Shien, Junichi Soh, Kazunori Okabe, Shuta Tomida, Masakiyo Sakaguchi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09286
[Presentation] Melanoma cell adhesion malecule (MCAM) induces dissemination of melanoma upon S100A8/S9 binding.2019
- Author(s)
  Tomonobu N, Kinoshita R, Kondo E, Yamauchi A, Futami J, Toyooka S, Sakaguchi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] S100 family protein: its role in inflammation associated with aging, Specific title: Prevention of cancer metastasis on the basis of identification of novel S100 protein sensor receptors2019
- Author(s)
  Masakiyo Sakaguchi
- Organizer
  National Symposium and Workshop in Anti-Aging Medicine (NASWAAM)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Development of novel biologics to prevent lung tropic cancer metastasis.2018
- Author(s)
  阪口政清
- Organizer
  The First International Symposium on Immunology and Cancer in Okayama / 13th URA International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] JNKによるリン酸化はSARM1のNAD分解活性を制御し、ミトコンドリア呼吸阻害を誘導する2018
- Author(s)
  村田　等、山本健一、木下理恵、阪口政清
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 膵がん進展に導く膵がん細胞-間質線維芽細胞クロストークを介在する分泌性S100A11ー受容体RAGE連携の役割2018
- Author(s)
  光井　洋介、山本健一、Sumardika I Wayan、木下理恵、村田　等、二見淳一郎、高松仁、山本靖彦、西堀正洋、豊岡伸一、渡部昌実、那須保友、阪口政清
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 分泌性S100A11-受容体RAGEシグナルに着眼した膵がん間質増大のメカニズムの解明2018
- Author(s)
  山本健一、高松仁志、光井洋介、木下理恵、村田　等、二見淳一郎、山本靖彦、西堀正洋、豊岡伸一、阪口政清
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Tumor-suppressive effect of LRIG1 in non-small cell lung cancer harboring mutant EGFR2018
- Author(s)
  鳥越英次郎、山本寛斎、阪口政清、難波圭、佐藤博紀、枝園和彦、諏澤憲、宗淳一、冨田秀太、佃和憲、三好新一郎、豊岡伸一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 新規HNF4γバリアントによる肝機能の誘導2018
- Author(s)
  佐々木翔太, 浦部瑞穂, 前田つかさ, 鈴木淳子, 入江亮太, 阪口政清, Frank J. Gonzalez, 井上裕介
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] Biological role of PODXL1 in invasion and metastasis of Pancreatic ductal adenocarinoma.2018
- Author(s)
  近藤英作、阪口政清、飯岡英和、齋藤憲
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 新規HNF4γバリアントによる肝機能の誘導2018
- Author(s)
  佐々木翔太、浦部瑞穂、前田つかさ、鈴木淳子、入江亮太、阪口政清、Frank J. Gonzalez、井上裕介
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 分泌性S100A11-受容体RAGEシグナルを介した膵臓がん周辺微小環境における間質線維芽細胞の増殖誘導の解明2018
- Author(s)
  山本健一、高松仁志、友信奈保子、光井洋介、二見淳一郎、木下理恵、村田等、阪口政清
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 核内受容体HNF4γによる肝がん細胞の再分化誘導2017
- Author(s)
  浦部瑞穂、佐々木翔太、前田つかさ、鈴木淳子、入江亮太、阪口政清、Gonzalez J. Frank、井上裕介
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] Application of hepatocyte nuclear factor 4γ for establishment of differentiated hepatocytes2017
- Author(s)
  S. Sasaki, M. Urabe, T. Maeda, J. Suzuki, R. Irie, M. Sakaguchi, F.J. Gonzalez, and Y. Inoue
- Organizer
  4th International Conference on Pharmaceutical and Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] S100タンパク質を基軸とした乾癬病態憎悪の分子メカニズムとその制御2017
- Author(s)
  阪口政清
- Organizer
  第16回岡山皮膚科スプリングセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] S100A8/A9を標的とした新しいがん制御法の開発2017
- Author(s)
  木下理恵　村田等　山本健一　許南浩　日比野利彦　阪口政清
- Organizer
  第90回日本組織培養学会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] S100A8/A9とその受容体との結合遮断を目指した転移抑制タンパク質製剤の開発2017
- Author(s)
  木下理恵,山内明,枝園和彦,富田秀太,豊岡伸一,近藤英作,坂口政清
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15245
[Presentation] 転移先臓器を感知する受容体2017
- Author(s)
  阪口政清、木下理恵、村田等、山本健一、日比野利彦、許南浩
- Organizer
  第90回日本組織培養学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] Crumbs3は焦点接着構成因子を制御することで大腸癌の転移を促進する2017
- Author(s)
  飯岡英和,齋藤憲,坂口政清,森井英一,近藤英作
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15245
[Presentation] S100A8/A9タンパク質と臓器指向性転移2017
- Author(s)
  阪口政清
- Organizer
  第28回創薬・薬理フォーラム岡山
- Invited
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 肝臓におけるmiRNAを介した新規HNF4αネットワークの解明2017
- Author(s)
  秋山萌、守本葵、神成真名、土田雄一、松田強志、齊藤千夏、佐々木翔太、前田つかさ、阪口政清、Frank Gonzalez、井上裕介
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] S100A8/A9とその受容体との結合遮断を目指した転移抑制タンパク質製剤の開発2017
- Author(s)
  木下理恵、村田等、井上祐介、近藤英作、許南浩、阪口政清
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 転移を制御する受容体2017
- Author(s)
  阪口政清
- Organizer
  岡山大学医学部技術部研修会
- Data Source
  KAKENHI-PROJECT-17H03577
[Presentation] 核内受容体HNF4γの機能解析2016
- Author(s)
  佐々木翔太, 浦部瑞穗, 前田つかさ, 入江亮太, 鈴木淳子, 阪口政清, Frank J. Gonzalez, 井上裕介
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] The cell polarity regulator Crumbs3 promotes2016
- Author(s)
  Hidekazu Iioka, Ken Saito, Masakiyo Sakaguchi, Eiichi Morii, Eisaku Kondo
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 核内受容体HNF4γの機能解析2016
- Author(s)
  佐々木翔太, 浦部瑞穗, 前田つかさ, 入江亮太, 鈴木淳子, 阪口政清, Frank J. Gonzalez, 井上裕介
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Beta3 integrin cDNA-transduced human keratinocytes grow far better on fibrin gels as compared to normal human keratinocytes2016
- Author(s)
  久保美代子, 阪口政清
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター (大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Interaction between Pancreatic cancer cells and MSC for cancer progression2016
- Author(s)
  Eisaku Kondo, Ken Saito, Hidekazu Iioka, Masakiyo Sakaguchi
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Extract of Cordyceps militaries inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells2016
- Author(s)
  イマデウィナルサルマ, エンディウィダヤプトラント, 近藤英作, 井上裕介, 山本健一, 村田等, 阪口政清
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター (大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 神経細胞死・軸索変性に関与するSARM1のリン酸化制御2016
- Author(s)
  村田等、西川茜、山本健一、木下理恵、阪口政清
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] HNF4αによるmiRNAを介した遺伝子発現制御機構の解析2016
- Author(s)
  秋山萌, 守本葵, 神成真名, 土田雄一, 松田強志, 齊藤千夏, 佐々木翔太, 前田つかさ, 阪口政清, Frank J.Gonzalez, 井上裕介
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Beta3 integrin cDNA-transduced human keratinocytes grow far better on fibrin gels as compared to normal human keratinocytes2016
- Author(s)
  久保美代子, 阪口政清
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Cytokeratin 19 binds to HER2 and activates HER2 and its downstream signaling2016
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Shuta Tomida, Hiromasa Yamamoto, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Junichi Soh, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] The cell polarity regulator Crumbs3 promotes adenocarcinoma metastasis through the regulation of glycolipid dynamics2016
- Author(s)
  Hidekazu Iioka, Ken Saito, Masakiyo Sakaguchi, Eiichi Morii, Eisaku Kondo
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] HNF4αによるmiRNAを介した遺伝子発現制御機構の解析2016
- Author(s)
  秋山萌, 守本葵, 神成真名, 土田雄一, 松田強志, 齊藤千夏, 佐々木翔太, 前田つかさ, 阪口政清, Frank J.Gonzalez, 井上裕介
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Regulation of Cellular Stress Response By Mitochondrial Kinase Pink12016
- Author(s)
  Hitoshi Murata, Hitoshi Takamatsu, Ken Kataoka, Nam-ho HUH, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター (大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Interaction between Pancreatic cancer cells and MSC for cancer progression2016
- Author(s)
  Eisaku Kondo, Ken Saito, Hidekazu Iioka, Masakiyo Sakaguchi
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Development of a novel biologics for suppression of S100A8/A9-induced cancer metastasis2016
- Author(s)
  Rie Kinoshita, Hitoshi Murata, Yusuke Inoue, Eisaku Kondo, Nam-Ho Huh, Masakiyo Sakaguchi
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Extract of Cordyceps militaries inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells2016
- Author(s)
  イマデウィナルサルマ, エンディウィダヤプトラント, 近藤英作, 井上裕介, 山本健一, 村田等, 阪口政清
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] 神経細胞死・軸索変性に関与するSARM1のリン酸化制御2016
- Author(s)
  村田等、西川茜、山本健一、木下理恵、阪口政清
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 浸潤性膵管癌におけるがん-間質相互反応の増殖・浸潤における役割2016
- Author(s)
  近藤英作,齋藤憲,飯岡英和,坂口政清
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K15245
[Presentation] Regulation of Cellular Stress Response By Mitochondrial Kinase Pink12016
- Author(s)
  Hitoshi Murata, Hitoshi Takamatsu, Ken Kataoka, Nam-ho HUH, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第89回大会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府豊中市)
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Development of a novel biologics for suppression of S100A8/A9-induced cancer metastasis2016
- Author(s)
  Rie Kinoshita, Hitoshi Murata, Yusuke Inoue, Eisaku Kondo, Nam-Ho Huh, Masakiyo Sakaguchi
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] S100A8 promoted Th1-related gene expression and S100A9 induced Th2 differentiation via activation of GATA-32015
- Author(s)
  Toshihiko Hibino, Masashi Miyai, Saeko Nakajima, Mami Yamamoto-Tanaka, Tatsuo Maeda, Masakiyo Sakaguchi, Kenji Kabashima、 Ryoji Tsuboi
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] S100A8 promoted Th1-related gene expression and S100A9 induced Th2 differentiation via activation of GATA-32015
- Author(s)
  Toshihiko Hibino, Masashi Miyai, Saeko Nakajima, Mami Yamamoto-Tanaka, Tatsuo Maeda, Masakiyo Sakaguchi, Kenji Kabashima、 Ryoji Tsuboi
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] HNF4γの転写活性化能の解析と相互作用タンパク質の探索2015
- Author(s)
  佐々木翔太, 前田つかさ, 浦部瑞穂, 鈴木淳子, 入江亮太, 阪口政清, Frank J. Gonzalez, 井上裕介
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460490
[Presentation] Potential role of tumor suppressor gene REIC/Dkk-3 as an inflammatory mediator in skin tissue2015
- Author(s)
  Yuki Ayabe, Taiki Tsuruda, Masakiyo Sakaguchi, Ken Kataoka
- Organizer
  ASCB annual meeting
- Place of Presentation
  カリフォルニア州サンディエーゴ
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] S100A8/A9 induces skin inflammation and keratinocyte proliferation via neuroplasatin-beta/EMMPRIN heterodimer receptor in atopic dermatitis2015
- Author(s)
  Masashi Miyai, Masakiyo Sakaguchi, Mami Yamamoto-Tanaka, Tatsuo Maeda, Junichiro Hiruma, Ryoji Tsuboi, Toshihiko Hibino
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 肺動脈性肺高血圧症におけるRAGEシグナルの亢進2015
- Author(s)
  中村一文、更科俊洋、赤木達、伊藤浩、阪口政清、大藤剛宏
- Organizer
  第4回日本肺循環学会・第3回日本肺高血圧学会　合同学術集会
- Place of Presentation
  東京
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] TIR/BB-loop mimetic AS-1 Inhibits Proliferation of Pulmonary Artery Smooth Muscle Cells from Patients with Pulmonary Arterial Hypertension2015
- Author(s)
  Kazufumi Nakamura, Masakiyo Sakaguchi, Toshihiro Sarashina, Satoshi Akagi, Aya Miura, Takahiro Oto, Aiko Ogawa, Hiromi Matsubara, Hiroshi Ito
- Organizer
  第79回日本循環器学会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] HNF4γの機能解析2015
- Author(s)
  佐々木翔太、前田つかさ、鈴木淳子、入江亮太、阪口政清、Frank J. Gonzalez、井上裕介
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  新潟
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25460490
[Presentation] Identification of a novel binding protein playing a critical role in HER2 activation in lung cancer cells2015
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] HNF4αはmiR-194/192を介して肝細胞の脱分化を抑制する2015
- Author(s)
  守本葵，神成真名，土田雄一，松田強志，齊藤千夏，佐々木翔太，前田つかさ，阪口政清，行木信一，Frank J Gonzalez，井上裕介
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460490
[Presentation] Identification of a novel binding protein playing a critical role in HER2 activation in lung cancer cells2015
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  フィラデルフィア州、ペンシルバニア
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] S100A8/A9 induces skin inflammation and keratinocyte proliferation via neuroplasatin-beta/EMMPRIN heterodimer receptor in atopic dermatitis2015
- Author(s)
  Masashi Miyai, Masakiyo Sakaguchi, Mami Yamamoto-Tanaka, Tatsuo Maeda, Junichiro Hiruma, Ryoji Tsuboi, Toshihiko Hibino
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] NRF2 pathway activation as a target to counteract mitochondrial dysfunction in Parkinson’s disease2015
- Author(s)
  Hitoshi Murata, Hitoshi Takamatsu, Nam-ho Huh, Masakiyo Sakaguchi
- Organizer
  The 9th ICME International Conference on Complex Medical Engineering (CME 2015)
- Place of Presentation
  岡山
- Year and Date
  2015-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Identification of a novel binding protein playing a critical role in HER2 activation in lung cancer cells2015
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  フィラデルフィア州、ペンシルバニア
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] TIR/BB-loop mimetic AS-1 Inhibits Proliferation of Pulmonary Artery Smooth Muscle Cells from Patients with Pulmonary Arterial Hypertension2015
- Author(s)
  Kazufumi Nakamura, Masakiyo Sakaguchi, Toshihiro Sarashina, Satoshi Akagi, Aya Miura, Takahiro Oto, Aiko Ogawa, Hiromi Matsubara, Hiroshi Ito
- Organizer
  第79回日本循環器学会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] TNF-αによるREIC/Dkk-3の発現制御とケラチノサイトの挙動への影響2015
- Author(s)
  綾部雄基、鶴田太輝、阪口政清、片岡健
- Organizer
  日本組織培養学会第88回大会
- Place of Presentation
  広島
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] NRF2 pathway activation as a target to counteract mitochondrial dysfunction in Parkinson’s disease2015
- Author(s)
  Hitoshi Murata, Hitoshi Takamatsu, Nam-ho Huh, Masakiyo Sakaguchi
- Organizer
  The 9th ICME International Conference on Complex Medical Engineering (CME 2015)
- Place of Presentation
  岡山
- Year and Date
  2015-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] TNF-αによるREIC/Dkk-3の発現制御とケラチノサイトの挙動への影響2015
- Author(s)
  綾部雄基、鶴田太輝、阪口政清、片岡健
- Organizer
  日本組織培養学会第88回大会
- Place of Presentation
  広島
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] 肺動脈性肺高血圧症におけるRAGEシグナルの亢進2015
- Author(s)
  中村一文、更科俊洋、赤木達、伊藤浩、阪口政清、大藤剛宏
- Organizer
  第4回日本肺循環学会・第3回日本肺高血圧学会　合同学術集会
- Place of Presentation
  東京
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Potential role of tumor suppressor gene REIC/Dkk-3 as an inflammatory mediator in skin tissue2015
- Author(s)
  uki Ayabe, Taiki Tsuruda, Masakiyo Sakaguchi, Ken Kataoka
- Organizer
  ASCB annual meeting
- Place of Presentation
  カリフォルニア州サンディエーゴ
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382
[Presentation] Anti-tumor effect of afatinib, an irreversible EGFR/HER2 dual inhibitor, in lung cancers harboring HER2 oncogene2015
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] 高機能REIC遺伝子発現アデノウイルスベクターの開発2014
- Author(s)
  阪口政清
- Organizer
  岡山大学機能強化戦略プロジェクト－難治固形がんの遺伝子治療－第２回シンポジウム
- Place of Presentation
  岡山市、岡山プラザホテル
- Year and Date
  2014-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 肝臓特異的HNF4α欠損マウスにおけるHNF4γの機能解析2014
- Author(s)
  佐々木翔太，前田つかさ，鈴木淳子，入江亮太，阪口政清，Frank J. Gonzalez，井上裕介
- Organizer
  第37回日本分子生物学会，
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460490
[Presentation] S100タンパク質によるケラチノサイトの増殖、死の分子制御機構2014
- Author(s)
  阪口政清
- Organizer
  資生堂研究所招待講演
- Place of Presentation
  横浜市、資生堂研究所
- Year and Date
  2014-08-07
- Invited
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] Identification of RAGE-coupled receptor that modulates RAGE-triggered signaling pathway2013
- Author(s)
  Masakiyo Sakaguchi, Hitoshi Murata, Toshihiko Hibino, Yumi Aoyama, Keiji Iwatsuki, Nam-ho Huh
- Organizer
  The American Society for Cell Biology (ASCB) annual meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] A super geneexpression system strongly enhances the anticancer effects of the REIC/Dkk-3 encoding adenoviral vector2013
- Author(s)
  Watanabe M.,Sakaguchi M.,Kaku H.,Ueki H.,Ariyoshi Y.,Hirata T.,Yoshioka T.,Huang P.,Li S-A.,Nasu Y.,Huh N.,Kumon H.
- Organizer
  Annual　Meeting　of Japan Society of Gene Therapy
- Place of Presentation
  Okayama，Okayama Convention Center
- Data Source
  KAKENHI-PROJECT-23390382
[Presentation] S100A8/A9 targets oncogenic survival pathway via RAGE that critically enhanced by a RAGE co-receptor(多機能受容体RAGEの共役受容体の発見とその意義)2013
- Author(s)
  Masakiyo Sakaguchi, Hitoshi Murata, Toshihiko Hibino, and Nam-ho Huh
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] Tumor Necrosis Factor-alpha down-regulates a tumor suppressor gene, REIC/Dkk-3, in normal skin keratinocytes2013
- Author(s)
  Kataoka K, Sakaguchi M, Murata H, Hashikawa N, Huh NH
- Organizer
  The 2013 In Vitro Biology Meeting
- Place of Presentation
  米国
- Data Source
  KAKENHI-PROJECT-24591943
[Presentation] 肝臓特異的HNF4α欠損マウスにおけるHNF4γの機能解析2013
- Author(s)
  前田つかさ、佐々木翔太、鈴木淳子、入江亮太、外丸靖浩、鈴木正則、太期健二、Gonzalez FJ、阪口政清、行木信一、井上裕介
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-25460490
[Presentation] 多機能受容体RAGEの共役受容体の発見とその意義2013
- Author(s)
  阪口　政清
- Organizer
  新学術領域「自然炎症」「脂質マシナリ」合同若手ワークショップ
- Place of Presentation
  鳴門市
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] S100A8 および S100A9 タンパク質の新規受容体の探索とそのがん進展における役割2012
- Author(s)
  阪口政清
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] 細胞内導入型RAGE阻害剤の開発2012
- Author(s)
  8. Putoranto Endy Widya、村田等、山本健一、片岡健、二見淳一郎、山田秀徳、阪口政清、許南浩
- Organizer
  日本組織培養学会第85回大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591943
[Presentation] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by our in Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2012
- Author(s)
  阪口政清
- Organizer
  2012 World Congress on In Vitro Biology
- Place of Presentation
  アメリカ、Bellevue
- Invited
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] S100A8およびS100A9タンパク質の新規受容体の探索とそのがん進展における役割2012
- Author(s)
  阪口政清
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] S100A8およびS100A9タンパク質の新規受容体の探索とそのがん進展における役割2012
- Author(s)
  阪口政清
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] Identification of novel receptors for pro-inflammatory S100A8/A9 proteins and their roles inmelanoma metastasis2012
- Author(s)
  阪口政清
- Organizer
  IEIIS2012. Homeostatic Inflammation Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by our in Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2012
- Author(s)
  阪口政清
- Organizer
  2012 World Congress on In Vitro Biology
- Place of Presentation
  アメリカ、Bellevue
- Invited
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by our in Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2012
- Author(s)
  阪口政清
- Organizer
  2012 World Congress on In Vitro Biology
- Place of Presentation
  アメリカ、Bellevue(招待講演)
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] S100A8およびS100A9タンパク質の新規受容体の探索とそのがん進展における役割2012
- Author(s)
  阪口政清
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified by our in Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-tumor Agent2012
- Author(s)
  阪口政清
- Organizer
  2012 World Congress on In Vitro Biology
- Place of Presentation
  アメリカ、Bellevue
- Year and Date
  2012-06-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] Identification of novel receptors for pro-inflammatory S100A8/A9 proteins and their roles inmelanoma metastasis2012
- Author(s)
  阪口政清
- Organizer
  IEIIS2012. Homeostatic Inflammation Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Identification of novel receptors for pro-inflammatory S100A8/A9 proteins and their roles inmelanoma metastasis2012
- Author(s)
  阪口政清
- Organizer
  IEIIS2012. Homeostatic Inflammation Symposium
- Place of Presentation
  東京
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PUBLICLY-24117711
[Presentation] REIC/Dkk-3の扁平上皮における発現とその制御因子の探索2011
- Author(s)
  片岡健、阪口政清、杜剛、前原奈都美、村田等、許南浩
- Organizer
  日本組織培養学会第84回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Promotion of migration and invasion of osteosarcoma cells by S100A7 through RAGE2011
- Author(s)
  Kataoka K, Sakaguchi M, Ono T, Morishita M, Yamamoto KI, Murata H, Huh NH
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] 多機能受容体 RAGE の下流信号伝達機構の解明2011
- Author(s)
  阪口政清
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] TIRAP is a critical transducer of RAGE-mediated inflammatory signaling2011
- Author(s)
  阪口政清
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] TIRAP is a critical transducer of RAGE-mediatedinflammatory signaling2011
- Author(s)
  Sakaguchi M, Murata H, Yamamoto KI, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Mitochondrial malfunction by PINK1 knockdown augments apoptosis induced by adenovirus carrying REIC/Dkk-32011
- Author(s)
  Murata H, Jin Y, Sakaguchi M, Kataoka K, Huh NH
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] PINK1 knockdown increases the apoptosis induced by adenovirus-mediated REIC/Dkk-3overexpression on bladder cancer cells2011
- Author(s)
  Jin Y, Murata H, Kataoka K, Sakaguchi M, Huh NH
- Organizer
  日本組織培養学会第84回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] 正常皮膚におけるREIC/Dkk-3の発現制御因子の検索2011
- Author(s)
  前原奈都美、片岡健、杜剛、村田等、山本健一、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Effect of Adenovirus-mediated Overexpression of REIC/Dkk-3 on Scirrhous Gastric Carcinoma Cells2010
- Author(s)
  Than SS, Kataoka K, Putranto EW, Murata H, Abarzua F, Taketa C, Yashiro M, Sakaguchi M, Huh NH
- Organizer
  日本組織培養学会第83回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] TIRAP, an adaptor protein for TLR-2/-4, transduces a signal from RAGE phosphorylated upon ligand binding.2010
- Author(s)
  Masakiyo Sakaguchi, Hitoshi Murata, Ken-ichi Yamamoto, Tomoyuki Ono, Yoshihiko Sakaguchi, Akira Motoyama, Toshihiko Hibino, Ken Kataoka, Nam-ho Huh.
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21689011
[Presentation] Reduced expression of REIC/Dkk-3, a putative tumor suppressor gene, in hyperproliferativeepidermis2010
- Author(s)
  Du G, Kataoka K, Sakaguchi M, Makino T, Shimizu T, Huh NH
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] TIRAP, an adaptor protein for TLR-2/-4, transduces a signal from RAGE phosphorylated upon ligand binding2010
- Author(s)
  阪口政清
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Intraperitoneal Administration of an Adenovirus Vector Carrying REIC/Dkk-3 Gene Suppresses Peritoneal Dissemination of Scirrhous Gastric Carcinoma Cells2010
- Author(s)
  Kataoka K, Than SS, Sakaguchi M, Abarzua F, Taketa C, Yashiro M, Nasu Y, Kumon H, Huh NH
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] PINK1/BRPK inhibits apoptotic cell death and enahances cellular invasiveness through an activation of mTORC2 pathway2010
- Author(s)
  Murata H, Sakaguchi M, Kataoka K, Huh NH
- Organizer
  The 16th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  ポルトガル
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] TIRAP, an adaptor protein for TLR-2/-4, transduces a signal from RAGE phosphorylated upon ligand binding(多機能受容体RAGEの下流信号伝達機構の解明)2010
- Author(s)
  Sakaguchi M, Murata H, Yamamoto KI, Ono T, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] TIRAP, an adaptor protein for TLR-2/-4, transduces a signal from RAGE phosphorylated upon ligand binding2010
- Author(s)
  Masakiyo Sakaguchi, Hitoshi Murata, Kenichi Yamamoto, Tomoyuki Ono, Yoshihiko Sakaguchi, Akira Motoyama, Toshihiko Hibino, Ken Kataoka, Nam-ho Huh
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21689011
[Presentation] 分化誘導したマウスES細胞及びiPS細胞におけるCy3標識REIC/Dkk-3タンパク質のエンドサートーシスによる取り込み2010
- Author(s)
  片岡健、阪口政清、李坤鵬、杜剛、武田千佳、舟橋弘晃、村田等、許南浩
- Organizer
  日本組織培養学会第83回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] BRPK/PINK1 promotes tumor progression through activation of mTORC2pathway2010
- Author(s)
  Murata H, Sakaguchi M, Jin Y, Kataoka K, Huh NH
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Promoter-based improvement of gene expression in cancer therapeutic adenovirus vector carrying REIC/Dkk-32009
- Author(s)
  阪口政清、片岡健、村田等、許南浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015031
[Presentation] Normal human fibroblasts mis-targetedly infected with adenovirus REIC have a tumor-suppressive ability in vivo2009
- Author(s)
  阪口政清、片岡健、フェルナンドアバルスア、谷本竜太、渡邉昌美、村田等、スエスエタン、那須保友、公文裕巳、許南浩
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20015031
[Presentation] 超高効率発現ベクターの開発とがん遺伝子治療薬としてのREIC/Dkk-3アデノウィルスベクターへの応用2009
- Author(s)
  阪口政清、片岡健、村田等、許南浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Promoter-based improvement of gene expression in cancer therapieutic adenovirus vector varrying REIC/Dkk-32009
- Author(s)
  阪口政清
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Intraperitoneal Normal human fibroblast mis-targetedly infected with adenovirus REIC have a tumor-suppressive abilitu in vivo2009
- Author(s)
  Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Nasu Y, Kumon H, Huh NH
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Normal human fibroblasts mis-targetedly infected with adenovirus REIC have a tumor-suppressive ability in vivo2009
- Author(s)
  阪口政清、片岡健、フェルナンドアバルスア、谷本竜太、渡邉昌美、村田等、スエスエタン、那須保友、公文裕巳、許南
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21689011
[Presentation] Promoter-based improvement of gene expression in cancer therapeutic adenovirus vector carrying REIC/Dkk-32009
- Author(s)
  阪口政清、片岡健、村田等、許南浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21689011
[Presentation] BRPK/PINK1のmTORC2経路活性化を介したがん浸潤への寄与2009
- Author(s)
  村田等、阪口政清、片岡健、許南浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591699
[Presentation] Over-expression of REIC/Dkk-3 induces IL-7 in normal human fibroblasts via ER stress2008
- Author(s)
  阪口政清
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20015031
[Presentation] S100All, an ambivalent mediator for growth regulation of human keratinocytes2007
- Author(s)
  Sakaguchi, et. al.
- Organizer
  Annual Meeting of American Association of Cell Biology
- Place of Presentation
  ワシントン(米国)
- Data Source
  KAKENHI-PROJECT-18013035
[Presentation] RAGE高発現がもたらす細胞形態変化と細胞運動亢進の分子機構の解析
- Author(s)
  山本健一、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] "PINK1発現抑制によるﾐﾄｺﾝﾄﾞﾘｱ機能不全はREIC/Dkk-3のｱﾎﾟﾄｰｿｼｽ誘導効果を増強する
- Author(s)
  村田等、金玉、阪口政清、片岡健、許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] "PINK1 knockdown increases the apoptosis induced by adenovirus-mediated REIC/Dkk-3 overexpression on bladder cancer cells "
- Author(s)
  "YU JIN, HITOSHI MURATA, KEN KATAOKA, MASAKIYO SAKAGUCHI, NAM-HO HUH"
- Organizer
  日本組織培養学会第８４回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] ロイコトリエンB4第一受容体BLT1とRAGEの相互作用
- Author(s)
  市木貴子、古賀友紹、奥野利明、阪口政清、横溝岳彦
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市、国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] S100A7による骨肉腫細胞の遊走・浸潤の多機能受容体RAGEを介した制御機構
- Author(s)
  片岡健、阪口政清、小野智之、森下美加、山本健一、村田等、許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Mitochondrial dysfunction by PINK1 knockdown augments apotosis induced by a gene-therspeutic adenovirus carrying REIC/Dkk-3
- Author(s)
  Hitoshi Murata, Jin Yu, Ken Kataoka, Masakiyo Sakaguchi, Nam-ho Huh
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Novel functional mutations in the transmembrane domain of HER2 gene in familial and sporadic lung adenocarcinomas
- Author(s)
  Hiromasa Yamamoto, Koichiro Higasa, Masakiyo Sakaguchi, Kazuhiko Shien, Junichi Soh, Koichi Ichimura, Masashi Furukawa, Shinsuke Hashida, Kazunori Tsukuda, Nagio Takigawa, Keitaro Matsuo, Katsuyuki Kiura, Shinichiro Miyoshi, Fumihiko Matsuda, Shinichi Toyooka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市、パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 正常皮膚におけるREIC/Dkk-3の発現制御因子の検索
- Author(s)
  前原奈都美、片岡健、杜剛、村田等、山本健一、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] 正常皮膚におけるREIC/Dkk-3の発現制御因子の検索
- Author(s)
  前原奈都美、片岡健、杜剛、村田等、山本健一、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] REIC/Dkk-3 の扁平上皮における発現とその制御因子の探索
- Author(s)
  片岡健, 阪口政清, 杜剛, 前原奈都美, 村田等, 許南浩
- Organizer
  日本組織培養学会第８４回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] "PINK1 knockdown increases the apoptosis induced by adenovirus-mediated REIC/Dkk-3 overexpression on bladder cancer cells "
- Author(s)
  "YU JIN, HITOSHI MURATA, KEN KATAOKA, MASAKIYO SAKAGUCHI, NAM-HO HUH"
- Organizer
  日本組織培養学会第８４回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] RAGE高発現がもたらす細胞形態変化と細胞運動亢進の分子機構の解析
- Author(s)
  山本健一、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Critical role of Cytokeratin-19 in an oncogenic activation of HER2
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市、パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 多機能受容体RAGEの下流信号伝達機構の解明
- Author(s)
  阪口政清、村田等、山本健一、阪口義彦本山晃、日比野利彦、片岡健　許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Mitochondrial dysfunction by PINK1 knockdown augments apotosis induced by a gene-therspeutic adenovirus carrying REIC/Dkk-3
- Author(s)
  Hitoshi Murata, Jin Yu, Ken Kataoka, Masakiyo Sakaguchi, Nam-ho Huh
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] TNF-aによるREIC/Dkk-3の表皮細胞における発現制御と増殖・分化の関係
- Author(s)
  綾部雄基、鶴田太輝、阪口政清、片岡健
- Organizer
  第9回日本臨床検査学教育学会学術大会
- Place of Presentation
  大田区産業プラザ（東京）
- Year and Date
  2014-08-20 – 2014-08-22
- Data Source
  KAKENHI-PROJECT-24591943
[Presentation] REIC/Dkk-3 の扁平上皮における発現とその制御因子の探索
- Author(s)
  片岡健, 阪口政清, 杜剛, 前原奈都美, 村田等, 許南浩
- Organizer
  日本組織培養学会第８４回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] 新規HER2膜貫通部領域遺伝子変異の機能解析
- Author(s)
  諏澤憲、阪口政清、山本寛斉、宗淳一、牧佑歩、橋田真輔、大塚智昭、渡邉元嗣、浅野博昭、佃和憲、三好新一郎、豊岡伸一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] S100タンパク質受容体の統合解析
- Author(s)
  森下美加、村田等、山本健一、片岡健、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] PINK1発現抑制によるﾐﾄｺﾝﾄﾞﾘｱ機能不全はREIC/Dkk-3のｱﾎﾟﾄｰｿｼｽ誘導効果を増強する
- Author(s)
  村田等、金玉、阪口政清、片岡健、許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] S100タンパク質受容体の統合解析
- Author(s)
  森下美加、村田等、山本健一、片岡健、阪口政清、許南浩
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650608
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation
- Author(s)
  Masahiro Nishibori, Hidenori Wake, Shuji Mori, Keyue Liu, Yuta Morioka, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Kosuke Kuroda, Hideo Takahashi, Aiji Ohtsuka, Tadashi Yoshino, and Hiroshi Morimatsu
- Organizer
  国際Sepsis Symposium
- Place of Presentation
  パリのパスツール研究所
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26290039
[Presentation] 多機能受容体RAGEの下流信号伝達機構の解明
- Author(s)
  阪口政清、村田等、山本健一、阪口義彦本山晃、日比野利彦、片岡健　許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] S100A7による骨肉腫細胞の遊走・浸潤の多機能受容体RAGEを介した制御機構
- Author(s)
  片岡健、阪口政清、小野智之、森下美加、山本健一、村田等、許南浩
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650625
[Presentation] Anti-tumor effect of afatinib, an irreversible EGFR/HER2 dual inhibitor, in lung cancers harboring HER2 oncogene
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-26293318

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SAKAGUCHI Masakiyo 阪口 政清

坂口 正清 サカグチ マサキヨ

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S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明Principal Investigator

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Identification of HRG that is highly inhibitory to S100A8/A9-mediated organ tropic cancer metastasisPrincipal Investigator

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SAKAGUCHI Masakiyo 阪口政清

坂口正清サカグチマサキヨ