Shimoda Masayuki 下田将之

… Alternative Names

SHIMODA Masayuki 下田将之

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Researcher Number	70383734
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京慈恵会医科大学, 医学部, 教授 2018 – 2023: 慶應義塾大学, 医学部(信濃町), 准教授 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 講師 2014 – 2015: 慶應義塾大学, 医学部, 講師 2014: 慶應義塾大学, 医学部, 専任講師 … More 2011 – 2013: 慶應義塾大学, 医学部, 助教 2009: 医学部, 助教 2007 – 2009: Keio University, 医学部, 助教 2006: 慶應義塾大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49030:Experimental pathology-related / Basic Section 49020:Human pathology-related / Experimental pathology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 55040:Respiratory surgery-related / Basic Section 54030:Infectious disease medicine-related / Respiratory surgery / Experimental pathology / Plastic surgery / Infectious disease medicine / Orthopaedic surgery / Biological Sciences
Keywords	Principal Investigator 線維芽細胞 / プロテアーゼ / がん / 細胞外マトリックス / がん微小環境 / 腫瘍間質 / 空間的発現解析 / 腫瘍免疫 / ヒアルロン酸 / 免疫細胞 … More / ヒアルロン酸代謝 / がん関連線維芽細胞 / エピゲノム / 網羅的解析 / メタロプロテアーゼ / 大腸 / 炎症 / 細胞・組織 / 病理学 / P-selectin glycoprotein ligand-1(PSGL-1) / a disintegrin and metalloproteinase(ADAM) / P-selectin / 転移 / 前立腺癌 / P-selectin glycoprote ligand-1(PSGL-1) / a disintegrin and metalloproteinase (ADAM) … More Except Principal Investigator 肺MAC症 / 肺移植 / 変形性関節症 / ADAM / 感染症 / 非結核性抗酸菌症 / 細胞外マトリックス / 拒絶反応 / 腎癌 / ADAMTS4 / ヒアルロン酸 / 創傷治癒 / 転移 / MMP / 狭窄 / 内視鏡的粘膜下層剥離術 / 消化管癌 / 肺癌 / 医工連携 / 末梢気道 / ファイバースコープ / 早期消化管癌 / 内視鏡的切除 / 医療用デバイス / 低侵襲治療 / 粘膜下局注 / 間葉系幹細胞 / 一酸化炭素 / 急性肺障害 / 肺虚血再灌流障害 / T細胞 / 肺サイトカイン / 肺虚血再灌流 / 肺由来間葉系幹細胞 / lung transplantation / mesenchymal stem cell / acute lung injury / 移植 / 制御性Ｔ細胞 / Ｔ細胞 / ヒアルロン酸分解酵素 / KIAA / KIAA1199 / 瘢痕 / 早期変形性関節症診断 / ADAMTS4/5 / 関節軟骨破壊機構 / ADAMTS / 滑膜細胞 / 関節軟骨細胞 / 骨・軟骨代謝 / ヒアルロン酸代謝 / 早期変形性関節症 / 関節軟骨破壊 / 早期変形性膝関節症 / HYBID / アグリカン分解 / ヒアルロン酸分解 / 肺移植拒絶反応 / マトリックスメタロプロテアーゼ / メタロプロテアーゼ / 血管 / EMT / 関節軟骨 / 急性大動脈解離 / 悪性腫瘍 / 組織リモデリング / TIMP / フォンビルブラント因子 / 酵素 / 分解 / アポトーシス / 増殖 / von Willebrand factor / ヘパラナーゼ / 筋線維芽細胞 / カルシウムペントサン硫酸 / CD44 / IL-1 / アグリカナーゼ / 血管新生 / 癌転移 / ELISA / セマフォリン / 動脈瘤 / エンドスタチン / 浸潤 / ノックアウトマウス Less

Development of new technologies for observation, biopsy, and treatment of peripheral airway lesions by medical-engineering collaboration
- Principal Investigator
  
  木下智成
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Jikei University School of Medicine
Establishment of preventive endoscopic intervention for gastrointestinal stenosis after endoscopic submucosal dissection by tissue engineering.
- Principal Investigator
  
  竹内洋司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Gunma University
肺MAC症の新規治療法開発に向けた菌細胞壁脂質の解析
- Principal Investigator
  
  西村知泰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Keio University
Creation and establishment of minimally invasive treatment for early-stage gastrointestinal cancer using multifunctional submucosal injection solution.
- Principal Investigator
  
  浦岡俊夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Gunma University
個細胞空間的degradome解析に基づくプロテアーゼを介したがん免疫制御の解明Principal Investigator
- Principal Investigator
  
  下田将之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Jikei University School of Medicine
Amelioration of acute lung injury by lung mesenchymal stem cell and carbon monoxide.
- Principal Investigator
  
  Ohtsuka Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Jikei University School of Medicine
Pathological analysis of HYBID-mediated hyaluronic acid metabolism involved in the tumor microenvironment creationPrincipal Investigator
- Principal Investigator
  
  Shimoda Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Jikei University School of Medicine
  Keio University
Elucidation of the pathophysiology of MAC pulmonary disease focusing on bacterial cell wall lipids
- Principal Investigator
  
  Nishimura Tomoyasu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Keio University
Amelioration of rejection after lung transplant by newly developed gas carrier.
- Principal Investigator
  
  Ohtsuka Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Jikei University School of Medicine
  Keio University
Mechanism of articular cartilage destruction in early-stage osteoarthritis and preclinical study on the development of diagnosis and treatment for early-stage osteoarthritis.
- Principal Investigator
  
  Yasunori Okada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
Analysis of cancer-associated fibroblasts from the perspective of proteinases and epigeneticsPrincipal Investigator
- Principal Investigator
  
  SHIMODA MASAYUKI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
Elucidation of the host immune response to nontuberculous mycobacterial cell wall lipids
- Principal Investigator
  
  NISHIMURA Tomoyasu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Keio University
Functional analysis of KIAA1199 in skin wound healing
- Principal Investigator
  
  ARAMAKI Noriko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Keio University
Ameliorating bronchiolitis oblietrans after transplantation using hemoglobin vesicles by controlling ADAM/MMP expressions.
- Principal Investigator
  
  Ohtsuka Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Keio University
Comprehensive analysis of metalloproteinases in cancer-associated fibroblastsPrincipal Investigator
- Principal Investigator
  
  Shimoda Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
Pathological study on metalloproteinases in tissue remodeling under pathological conditions
- Principal Investigator
  
  OKADA Yasunori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
ADAM28の癌細胞増殖・浸潤・転移における作用解析
- Principal Investigator
  
  岡田保典
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Roles of a disintegrin and metalloproteinases (ADAMs) in inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  SHIMODA Masayuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
Functional analyses and regulation of the metabolism of tissue microenvironmental factors by metalloproteinases
- Principal Investigator
  
  OKADA Yasunori
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
ヒト癌細胞浸潤・転移におけるADAM28の役割解析Principal Investigator
- Principal Investigator
  
  下田将之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University

[Book] Cowden病/PTEN過誤腫症候群. 九嶋亮治，牛久哲男編. 腫瘍病理鑑別診断アトラス十二指腸・小腸・虫垂腫瘍2021
- Author(s)
  下田将之，岩男泰，金井弥栄
- Total Pages
  3
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19K07422
[Book] 【消化器内視鏡医に必要な病理の基礎知識】良悪性の鑑別が問題となる腸病変の病理学的特徴. 消化器内科2021
- Author(s)
  会澤大介，岩男泰，下田将之
- Total Pages
  8
- Publisher
  医学出版
- Data Source
  KAKENHI-PROJECT-19K07422
[Book] Cronkhite-Canada症候群. 九嶋亮治，牛久哲男編. 腫瘍病理鑑別診断アトラス十二指腸・小腸・虫垂腫瘍2021
- Author(s)
  下田将之，岩男泰，金井弥栄
- Total Pages
  3
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19K07422
[Book] 実験医学2014
- Author(s)
  下田将之、岡田保典
- Total Pages
  9
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25860276
[Book] 「MMP/ADAM」、『炎症・再生医学事典(松島綱治、西脇徹編)』2009
- Author(s)
  下田将之、岡田保典
- Publisher
  朝倉書店出版
- Data Source
  KAKENHI-PROJECT-20790291
[Book] 「癌細胞-細胞外基質への接着能の測定法」、『がん転移研究の実験手法(済木育夫、愛甲孝編)2008
- Author(s)
  下田将之、岡田保典
- Publisher
  金芳堂出版
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Impact of neoadjuvant bevacizumab on neuroradiographic response and histological findings related to tumor stemness and hypoxic tumor microenvironment in glioblastoma: Paired comparison between newly diagnosed and recurrent glioblastomas.2022
- Author(s)
  Takei J, Fukasawa N, Tanaka T, Yamamoto Y, Tamura R, Sasaki H, Akasaki Y, Kamata Y, Murahashi M, Shimoda M, Murayama Y.
- Journal Title
  
  Front Oncol
  
  Volume: 12 Pages: 898614-898614
- DOI
  10.3389/fonc.2022.898614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09161, KAKENHI-PROJECT-23K24116
[Journal Article] Extracellular PKCδ signals to epidermal growth factor receptor for tumor proliferation in liver cancer cells2022
- Author(s)
  Yamada Kohji、Kizawa Ryusuke、Yoshida Ayano、Koizumi Rei、Motohashi Saya、Shimoyama Yuya、Hannya Yoshito、Yoshida Saishu、Oikawa Tsunekazu、Shimoda Masayuki、Yoshida Kiyotsugu
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 7 Pages: 2378-2385
- DOI
  10.1111/cas.15386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03519, KAKENHI-PROJECT-23K24116
[Journal Article] S100‐stained perineural invasion is associated with worse prognosis in stage I/II colorectal cancer: Its possible association with immunosuppression in the tumor2022
- Author(s)
  Fukuda Yumiko、Tanaka Yoshihiro、Eto Ken、Ukai Natsuko、Sonobe Shoko、Takahashi Hiroyuki、Ikegami Masahiro、Shimoda Masayuki
- Journal Title
  
  Pathology International
  
  Volume: 72 Issue: 2 Pages: 117-127
- DOI
  10.1111/pin.13195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] The highest percentage of Gleason Pattern 4 is a predictor in intermediate‐risk prostate cancer2022
- Author(s)
  Sato Shun、Kimura Takahiro、Onuma Hajime、Egawa Shin、Shimoda Masayuki、Takahashi Hiroyuki
- Journal Title
  
  BJUI Compass
  
  Volume: 4 Issue: 2 Pages: 234-240
- DOI
  10.1002/bco2.195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24116
[Journal Article] Epithelium Replacement Contributes to Field Expansion of Squamous Epithelium and Ulcerative Colitis?Associated Neoplasia2022
- Author(s)
  Sugimoto Shinya、Iwao Yasushi、Shimoda Masayuki、Takabayashi Kaoru、Sato Toshiro、Kanai Takanori、Keio IBD Collaborators
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 1 Pages: 334-337
- DOI
  10.1053/j.gastro.2021.09.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K19540, KAKENHI-PROJECT-21K16010, KAKENHI-PROJECT-20H03746
[Journal Article] Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B<sup>+</sup>vesicle pathway in liver cancer2022
- Author(s)
  Yamada Kohji、Motohashi Saya、Oikawa Tsunekazu、Tago Naoko、Koizumi Rei、Ono Masaya、Tachibana Toshiaki、Yoshida Ayano、Yoshida Saishu、Shimoda Masayuki、Oka Masahiro、Yoneda Yoshihiro、Yoshida Kiyotsugu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 36
- DOI
  10.1073/pnas.2202730119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06192, KAKENHI-PROJECT-22K08063, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20H03519, KAKENHI-PROJECT-20K07621, KAKENHI-PROJECT-23K24116
[Journal Article] MUC6 expression is a preferable prognostic marker for invasive mucinous adenocarcinoma of the lung2022
- Author(s)
  Yamanoi K, Fujii C, Yuzuriha H, Kumazawa M, Shimoda M, Emoto K, Asamura H, Nakayama J
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: Online ahead of print Issue: 6 Pages: 671-684
- DOI
  10.1007/s00418-022-02093-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03441, KAKENHI-PROJECT-19K16555, KAKENHI-PROJECT-23K24116
[Journal Article] Lymphomatoid gastropathy/NK-cell enteropathy involving the stomach and intestine2022
- Author(s)
  Nakajima Makoto、Shimoda Masayuki、Takeuchi Kengo、Dobashi Akito、Kanai Takanori、Kanai Yae、Iwao Yasushi
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 62 Issue: 2 Pages: 114-118
- DOI
  10.3960/jslrt.21032
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24116
[Journal Article] CD163‐positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma2021
- Author(s)
  Matsubara Eri、Komohara Yoshihiro、Shinchi Yusuke、Mito Remi、Fujiwara Yukio、Ikeda Koei、Shima Toshiyuki、Shimoda Masayuki、Kanai Yae、Sakagami Takuro、Suzuki Makoto
- Journal Title
  
  Pathology International
  
  Volume: 71 Issue: 10 Pages: 666-673
- DOI
  10.1111/pin.13144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-21H02705
[Journal Article] Closure of gastric perforations during endoluminal resection using a novel biodegradable collagen sol: A feasibility survival study on porcine model (with video)2021
- Author(s)
  Uraoka Toshio、Yunoki Shunji、Sasaki Motoki、Kinoshita Satoshi、Takatori Yusaku、Hirai Yuichiro、Narita Takefumi、Ramberan Hemchand、Shimoda Masayuki、Yahagi Naohisa
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 34 Issue: 1 Pages: 105-112
- DOI
  10.1111/den.13962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] A Solitary Submucosal Heterotopic Gastric Gland With Remarkable Growth During Follow-Up2021
- Author(s)
  Matsuura Noriko、Kato Motohiko、Shimoda Masayuki、Yahagi Naohisa
- Journal Title
  
  American Journal of Gastroenterology
  
  Volume: 117 Pages: 218-218
- DOI
  10.14309/ajg.0000000000001546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] Superficial nonampullary duodenal epithelial tumor: a rare case accompanied by cancer component as subepithelial lesion2021
- Author(s)
  Nakayama Atsushi、Kato Motohiko、Shimoda Masayuki、Yahagi Naohisa
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: 94 Issue: 2 Pages: 427-428
- DOI
  10.1016/j.gie.2021.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] Demarcated redness associated with increased vascular density/size: a useful marker of flat-type dysplasia in patients with ulcerative colitis2021
- Author(s)
  Ikebata Akiyoshi、Shimoda Masayuki、Okabayashi Koji、Uraoka Toshio、Maehata Tadateru、Sugimoto Shinya、Mutaguchi Makoto、Naganuma Makoto、Kameyama Kaori、Yahagi Naohisa、Kanai Takanori、Kitagawa Yuko、Kanai Yae、Iwao Yasushi
- Journal Title
  
  Endoscopy International Open
  
  Volume: 09 Issue: 04 Pages: E552-E561
- DOI
  10.1055/a-1352-2709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-21H02705, KAKENHI-PROJECT-20H03746
[Journal Article] Colectomy risk score predicts pouchitis in patients with ulcerative colitis2021
- Author(s)
  Ikebata Akiyoshi、Okabayashi Koji、Tsuruta Masashi、Shigeta Kohei、Seishima Ryo、Shimoda Masayuki、Naganuma Makoto、Kitagawa Yuko
- Journal Title
  
  Updates in Surgery
  
  Volume: 74 Issue: 2 Pages: 649-655
- DOI
  10.1007/s13304-021-01166-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] Deletion of Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization (HYBID) Results in Attenuation of Osteoarthritis in Mice2021
- Author(s)
  Momoeda Masahiro、de Vega Susana、Kaneko Haruka、Yoshinaga Chiho、Shimoda Masayuki、Nakamura Tomomi、Endo Yoko、Yoshida Hiroyuki、Kaneko Kazuo、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 191 Issue: 11 Pages: 1986-1998
- DOI
  10.1016/j.ajpath.2021.07.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-18K09082
[Journal Article] Infiltration of tumor‐associated macrophages is involved in tumor programmed death‐ligand 1 expression in early lung adenocarcinoma2020
- Author(s)
  Shima Toshiyuki、Shimoda Masayuki、Shigenobu Takao、Ohtsuka Takashi、Nishimura Tomoyasu、Emoto Katsura、Hayashi Yuichiro、Iwasaki Tatsuro、Abe Takayuki、Asamura Hisao、Kanai Yae
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 2 Pages: 727-738
- DOI
  10.1111/cas.14272
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08581, KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-17K10800
[Journal Article] The rough colony morphotype of Mycobacterium avium exhibits high virulence in human macrophages and mice2020
- Author(s)
  Nishimura Tomoyasu、Shimoda Masayuki、Tamizu Eiko、Uno Shunsuke、Uwamino Yoshifumi、Kashimura Shoko、Yano Ikuya、Hasegawa Naoki
- Journal Title
  
  Journal of Medical Microbiology
  
  Volume: 69 Issue: 7 Pages: 1020-1033
- DOI
  10.1099/jmm.0.001224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-19K08936
[Journal Article] Stromal metalloproteinases: Crucial contributors to the tumor microenvironment2020
- Author(s)
  Shimoda Masayuki、Ohtsuka Takashi、Okada Yasunori、Kanai Yae
- Journal Title
  
  Pathology International
  
  Volume: 71 Issue: 1 Pages: 1-14
- DOI
  10.1111/pin.13033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-19H03788
[Journal Article] <p>The Impact of Smoking on Pulmonary Metastasis in Colorectal Cancer</p>2020
- Author(s)
  Makino Akitsugu、Tsuruta Masashi、Okabayashi Koji、Ishida Takashi、Shigeta Kohei、Seishima Ryo、Ikebata Akiyoshi、Koishikawa Kaoru、Hasegawa Hirotoshi、Shimoda Masayuki、Fukunaga Koichi、Betsuyaku Tomoko、Kitagawa Yuko
- Journal Title
  
  OncoTargets and Therapy
  
  Volume: Volume 13 Pages: 9623-9629
- DOI
  10.2147/ott.s263250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422
[Journal Article] Dehydroxymethylepoxyquinomicin, a novel nuclear factor-κB inhibitor, prevents the development of cyclosporine A nephrotoxicity in a rat model2020
- Author(s)
  Morita Shinya、Shinoda Kazunobu、Yoshida Tadashi、Shimoda Masayuki、Kanno Yoshihiko、Mizuno Ryuichi、Kono Hidaka、Asanuma Hiroshi、Nakagawa Ken、Umezawa Kazuo、Oya Mototsugu
- Journal Title
  
  BMC Pharmacology and Toxicology
  
  Volume: 21 Issue: 1 Pages: 1-12
- DOI
  10.1186/s40360-020-00432-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-19K09738, KAKENHI-PROJECT-18H02939
[Journal Article] Extracellular vesicle-associated MMPs: A modulator of the tissue microenvironment2019
- Author(s)
  Shimoda Masayuki
- Journal Title
  
  Advances in Clinical Chemistry
  
  Volume: 88 Pages: 35-66
- DOI
  10.1016/bs.acc.2018.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08719
[Journal Article] The prevention of tracheal graft occlusion using pioglitazone: A mouse tracheal transplant model study.2019
- Author(s)
  Shigenobu T, Ohtsuka T ,Shimoda M
- Journal Title
  
  Transplant Immunology
  
  Volume: 53 Pages: 21-27
- DOI
  10.1016/j.trim.2018.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10800, KAKENHI-PROJECT-18K08581
[Journal Article] Inhibition of ADAM10 in satellite cells accelerates muscle regeneration following muscle injury2018
- Author(s)
  Mizuno Sakiko、Yoda Masaki、Shimoda Masayuki、Chiba Kazuhiro、Nakamura Masaya、Horiuchi Keisuke
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: 36 Issue: 8 Pages: 2259-2265
- DOI
  10.1002/jor.23878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08719
[Journal Article] Targeted deletion of HYBID (hyaluronan binding protein involved in hyaluronan depolymerization/ KIAA1199/CEMIP) decreases dendritic spine density in the dentate gyrus through hyaluronan accumulation2018
- Author(s)
  Yoshino Yuta、Shimazawa Masamitsu、Nakamura Shinsuke、Inoue Shintaro、Yoshida Hiroyuki、Shimoda Masayuki、Okada Yasunori、Hara Hideaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 503 Issue: 3 Pages: 1934-1940
- DOI
  10.1016/j.bbrc.2018.07.138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05454, KAKENHI-PROJECT-16J11526, KAKENHI-PROJECT-16K08719
[Journal Article] Isolation of cancer stem cells from human lung carcinoma cell lines by Hoechst side population method.2018
- Author(s)
  Shimoda M, Ota M, Okada Y
- Journal Title
  
  Methods Molec Biol
  
  Volume: 1692 Pages: 49-59
- DOI
  10.1007/978-1-4939-7401-6_5
- ISBN
  9781493974009, 9781493974016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08719
[Journal Article] Selective inhibition of ADAM28 suppresses lung carcinoma cell growth and metastasis2018
- Author(s)
  Satsuki Mochizuki, Masayuki Shimoda, Hitoshi Abe, Yuka Miyamae, Junko Kuramoto, Noriko Aramaki-Hattori, Ken Ishii, Hideki Ueno, Akira Miyakoshi, Kanehisa Kojoh and Yasunoti Okada
- Journal Title
  
  Mol. Cancer Ther
  
  Volume: 17 Issue: 11 Pages: 2427-2438
- DOI
  10.1158/1535-7163.mct-17-1198
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07052, KAKENHI-PROJECT-16K08719
[Journal Article] ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death2018
- Author(s)
  Ueno Mari、Shiomi Takayuki、Mochizuki Satsuki、Chijiiwa Miyuki、Shimoda Masayuki、Kanai Yae、Kataoka Fumio、Hirasawa Akira、Susumu Nobuyuki、Aoki Daisuke、Okada Yasunori
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 2 Pages: 471-482
- DOI
  10.1111/cas.13469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19611, KAKENHI-PROJECT-15K08409, KAKENHI-PROJECT-16K08719, KAKENHI-PROJECT-16K11156
[Journal Article] Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Is Up-Regulated and Involved in Hyaluronan Degradation in Human Osteoarthritic Cartilage.2018
- Author(s)
  Shimizu H, Shimoda M, Mochizuki S, Miyamae Y, Abe H, Chijiiwa M, Yoshida H, Shiozawa J, Ishijima M, Kaneko K, Kanaji A, Nakamura M, Toyama Y, Okada Y.
- Journal Title
  
  Am J Pathol.
  
  Volume: 188 Issue: 9 Pages: 2109-2119
- DOI
  10.1016/j.ajpath.2018.05.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10941, KAKENHI-PROJECT-18K07052, KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-16H05454, KAKENHI-PROJECT-16K08719
[Journal Article] SOX4, an epithelial-mesenchymal transition inducer, transactivates ADAM28 gene expression and co-localizes with ADAM28 at the invasive front of human breast and lung carcinomas2018
- Author(s)
  Aya Sasaki, Hitoshi Abe, Satsuki Mochizuki, Masayuki Shimoda and Yasunori Okada
- Journal Title
  
  Pathol Int.
  
  Volume: - Issue: 8 Pages: 449-458
- DOI
  10.1111/pin.12685
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07052, KAKENHI-PROJECT-16K08719
[Journal Article] Hyaluronan-binding protein involved in hyaluronan depolymerization controls endothelial ossification through hyaluronan metabolism.2017
- Author(s)
  Shimoda M., Yoshida H., Mizuno S., Hirozane T., Horiuchi K., Yoshino Y., Hara H., Kanai Y., Inoue S., Ishijima M. and Okada Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 187 Pages: 1162-1176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05454
[Journal Article] Distribution and function of hyaluronan binding protein involved in hyaluronan depolymerization (HYBID, KIAA1199) in the mouse central nervous system2017
- Author(s)
  Yuta Yoshino, Mitsue Ishisaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hiroyuki Yoshida, Shintaro Inoue, Masayuki Shimoda, Yasunori Okada, Hideaki Hara
- Journal Title
  
  Neuroscience
  
  Volume: 347 Pages: 1-10
- DOI
  10.1016/j.neuroscience.2017.01.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J11526, KAKENHI-PROJECT-16H05454
[Journal Article] Hyaluronan binding protein involved in hyaluronan depolymerization controls endothelial ossification through hyaluronan metabolism.2017
- Author(s)
  Shimoda M., Yoshida H., Mizuno S., Hirozane T., Horiuchi K., Yoshino Y., Hara H., Kanai Y., Inoue S., Ishijima M. and Okada Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 187 Issue: 5 Pages: 1162-1176
- DOI
  10.1016/j.ajpath.2017.01.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05454, KAKENHI-PROJECT-16J02900, KAKENHI-PROJECT-16J11526, KAKENHI-PROJECT-16K08719, KAKENHI-PROJECT-15K10494
[Journal Article] Metalloproteinases in extracellular vesicles.2017
- Author(s)
  Shimoda M, Khokha R
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1864 Issue: 11 Pages: 1989-2000
- DOI
  10.1016/j.bbamcr.2017.05.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08719
[Journal Article] Tumor suppression by stromal TIMPs2016
- Author(s)
  Shimoda M, Jackson HW and Khokha R
- Journal Title
  
  Cellular and Molecular Oncology
  
  Volume: － Issue: 3 Pages: e975082-e975082
- DOI
  10.4161/23723556.2014.975082
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860276
[Journal Article] Epithelial cell-derived a disintegrin and metalloproteinase-17 confers resistance to colonic inflammation through EGFR activation2016
- Author(s)
  Shimoda M, Horiuchi K, Sasaki A, Tsukamoto T, Okabayashi K, Hasegawa H, Kitagawa Y and Okada Y
- Journal Title
  
  EBioMedicine
  
  Volume: 5 Pages: 114-24
- DOI
  10.1016/j.ebiom.2016.02.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860276, KAKENHI-PROJECT-16H05454, KAKENHI-PROJECT-15K08960
[Journal Article] Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.2015
- Author(s)
  Anzai A., Shimoda M., Endo J., Kohno T., Katsumata ., Matsuhashi T., Yamamoto T., Ito K., Yan X., Shirakawa K., Shimizu-Hirota R., Yamada Y., Ueha S., Shinmura K., Okada Y., Fukuda K. and Sano M.
- Journal Title
  
  Circ Res
  
  Volume: 116 Pages: 612-623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249022
[Journal Article] Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state.2014
- Author(s)
  Shimoda M, Principe S, Jackson HW, Luga V, Fang H, Molyneux SD, Shao YW, Aiken A, Waterhouse PD, Karamboulas C, Hess FM, Ohtsuka T, Okada Y, Ailles L, Ludwig A, Wrana JL, Kislinger T and Khokha R
- Journal Title
  
  Nature Cell Biology
  
  Volume: 16 Pages: 889-901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860276
[Journal Article] メタロプロテアーゼによる組織内微小環境因子代謝2014
- Author(s)
  下田将之、岡田保典
- Journal Title
  
  病理と臨床
  
  Volume: 32 Pages: 24-30
- Data Source
  KAKENHI-PROJECT-25860276
[Journal Article] Loss of the TIMP gene family is sufficient for the acquisition of the CAF-like cell state.2014
- Author(s)
  Shimoda M., Principe S., Jackson H.W., Luga V., Fang H., Molyneux S.D., Shao Y.W., Aiken A., Waterhouse P.D., Karamboulas C., Hess F.M., Ohtsuka T., Okada Y., Ailles L., Ludwig A., Wrana J.L., Kislinger T. and Kohkha R.
- Journal Title
  
  Nat Cell Biol
  
  Volume: 16 Pages: 889-901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249022
[Journal Article] Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection2012
- Author(s)
  Kurihara T., Shimizu-Hirota R., Shimoda M., Adachi T., Shimizu H., Weiss S. J., Itoh H., Hori S., Aikawa N. and Okada Y
- Journal Title
  
  Circulation
  
  Volume: 126 Issue: 25 Pages: 3070-3080
- DOI
  10.1161/circulationaha.112.097097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249022
[Journal Article] Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor2012
- Author(s)
  Mochizuki S., Soejima K., Shimoda M., Abe H., Sasaki A., Okano H. J., Okano H. and Okada Y
- Journal Title
  
  J. Natl. Cancer Inst
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Effect of ADAM28 on Carcinoma Cell Metastasis by Cleavage of von Willebrand Factor2012
- Author(s)
  Satsuki Mochizuki
- Journal Title
  
  Journal of the National Cancer Institute
  
  Volume: 104(In press) Issue: 12 Pages: 906-922
- DOI
  10.1093/jnci/djs232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590421, KAKENHI-PROJECT-24249022, KAKENHI-PROJECT-24590490
[Journal Article] High-mobility group box 1 protein blockade suppresses development of abdominal aortic aneurysm2012
- Author(s)
  Kohno T., Anzai T., Kaneko H., Sugano Y., Shimizu H., Shimoda M., Miyasho T., Okamoto M., Yokota H., Yamada S., Yoshikawa T., Okada Y., Yozu R., Ogawa S. and Fukuda K
- Journal Title
  
  J Cardiol
  
  Volume: 59 Issue: 3 Pages: 299-306
- DOI
  10.1016/j.jjcc.2012.01.007
- NAID
  10031187749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249022
[Journal Article] Role of vascular endothelial growth factor-A in development of abdominal aortic aneurysm2011
- Author(s)
  Kaneko H., Anzai T., Takahashi T., Kohno T., Shimoda M., Sasaki A., Shimizu H., Nagai T., Maekawa Y., Yoshimura K., Aoki H., Yoshikawa T., Okada Y., Yozu R., Ogawa S., Fukuda K.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 91 Pages: 358-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Tumor necrosis factor-α converting enzyme is a key mediator of abdominal aortic aneurysm development2011
- Author(s)
  Kaneko H., Anzai T., Horiuchi K., Kohno T., Nagai T., Anzai A., Takahashi T., Sasaki A., Shimoda M., Maekawa Y., Shimizu H., Yoshikawa T., Okada Y., Yozu R., Fukuda K.
- Journal Title
  
  Atherosclerosis
  
  Volume: 218 Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Resveratrol prevents development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization2011
- Author(s)
  Kaneko H., Anzai T., Morisawa M., Kohno T., Nagai T., Anzai A., Takahashi T., Shimoda M., Sasaki A., Maekawa Y., Yoshimura K., Aoki H., Tsubota K., Yoshikawa T., Okada Y., Ogawa S., Fukuda K.
- Journal Title
  
  Atherosclerosis
  
  Volume: 217 Pages: 350-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Tumor necrosis factor-αconverting enzyme is a key mediator of abdominal aortic aneurysm development2011
- Author(s)
  Kaneko H., Anzai T., Horiuchi K., Kohno T., Nagai T., Anzai A., Takahashi T., Sasaki A., Shimoda M., Maekawa Y., Shimizu H., Yoshikawa T., Okada Y., Yozu R. and Fukuda K
- Journal Title
  
  Atherosclerosis
  
  Volume: 218 Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Connective tissue growth factor is a substrate of ADAM282010
- Author(s)
  Mochizuki, S., Tanaka R., Shimoda M., Onuma J., Fujii Y., Jinno H. and Okada Y
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 402 Pages: 651-657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] ADAM28 is a serological and histochemical marker for non-small-cell lung cancers2010
- Author(s)
  Kuroda H, Mochizuki S, Shimoda M, Chijiiwa M, Kamiya K, Izumi Y, Watanabe M, Horinouchi H, Kawamura M, Kobayashi K, Okada Y.
- Journal Title
  
  Int. J. Cancer (in press)
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] ADAM28 is a serological and histochemical marker for non-small-cell lung cancers2010
- Author(s)
  Kuroda H, Mochizuki S, Shimoda M, Chijiiwa M, Kamiya K, Izumi Y, Watanabe M, Horinouchi H, Kawamura M, Kobavashi K, Okada Y
- Journal Title
  
  Int.J.Cancer (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Connective tissue growth factor is a substrate of ADAM28.2010
- Author(s)
  Mochizuki, S., Tanaka R., Shimoda M., Onuma J., Fujii Y., Jinno H., Okada Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 402 Pages: 651-657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.2010
- Author(s)
  Kuroda H., Mochizuki S., Shimoda M., Chijiiwa M., Kamiya K., Izumi Y., Watanabe M., Horinouchi H., Kawamura M., Kobayashi K., Okada Y.
- Journal Title
  
  Int J Cancer (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.2010
- Author(s)
  Kuroda H., Mochizuki S., Shimoda M., Chijiiwa M., Kamiya K., Izumi Y., Watanabe M., Horinouchi H., Kawamura M., Kobayashi K., Okada Y.
- Journal Title
  
  Int J Cancer
  
  Volume: 127 Pages: 1844-1856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] ADAM28 is a serological and histochemical marker for non-small-cell lung cancers2010
- Author(s)
  Kuroda H., Mochizuki S., Shimoda M., Chijiiwa M., Kamiya K., Izumi Y., Watanabe M., Horinouchi H., Kawamura M., Kobayashi K. and Okada Y
- Journal Title
  
  Int. J. Cancer
  
  Volume: 127 Pages: 1844-1856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons2009
- Author(s)
  Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S
- Journal Title
  
  Molecular Psychiatry 14
  
  Pages: 206-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Multiple Aneurysms of the Splenic Artery Caused by Fibromuscular Dysplasia2009
- Author(s)
  Watada S, Obara H, Shimoda M, Matsubara K, Matsumoto K, Kitajima M
- Journal Title
  
  Ann. Vasc. Surg. 23
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Amyloid-・ causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons2009
- Author(s)
  Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S
- Journal Title
  
  Mol. Psychiatry 14
  
  Pages: 206-222
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Expression of heparanase in renal cell carcinomas: Implications for tumor invasion and progression.2008
- Author(s)
  Mikami S., Oya M., Shimoda M., Mizuno R., Ishida M., Kosaka T., Mukai M., Nakajima M. Okada Y.
- Journal Title
  
  Clin. Cancer Res. 14
  
  Pages: 6055-6061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Expression of Heparanase in Renal Cell Carcinomas: Implications for Tumor Invasion and Prognosis2008
- Author(s)
  Mikami S, Oya M, Shimoda M, Mizuno R, Ishida M, Kosaka T, Mukai M, Nakajima M, Okada Y
- Journal Title
  
  Clin. Cancer Res. 14
  
  Pages: 6055-6061
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Primary invasive micropapillary carcinoma of the stomach2008
- Author(s)
  Shimoda M, Okada Y, Hayashi Y, Hatano S, Kawakubo H, Omori T, Ishii S, Sugiura H
- Journal Title
  
  Pathology International 58
  
  Pages: 513-517
- NAID
  10027377498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Expression of Heparanase in Renal Cell Carcinomas : Implications for Tumor Invasion and Prognosis2008
- Author(s)
  Mikami S, Oya M, Shimoda M. Mizuno R, Ishida M, Kosaka T Mukai M, Nakajima M, Okada Y
- Journal Title
  
  Clinical Cancer Research 14
  
  Pages: 6055-6061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Primary invasive micropapillary carcinoma of the stomach2008
- Author(s)
  Shimoda M, Okada Y, Hayashi Y, Hatano S, Kawakubo H, Omori T, Ishii S, Sugiura H
- Journal Title
  
  Pathol. Int. 58
  
  Pages: 513-517
- NAID
  10027377498
- Data Source
  KAKENHI-PROJECT-20790291
[Journal Article] Expression of heparanase in renal cell carcinomas : Implications for tumor invasion and progression2008
- Author(s)
  Mikami S., Oya M., Shimoda M., Mizuno R., Ishida M., Kosaka T., Mukai M., Nakajima M. and Okada Y.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 6055-6061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013040
[Journal Article] Binding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cells2007
- Author(s)
  Shimoda M., Hashimoto G., Mochizuki S., Ikeda E., Nagai N., Ishida S. and Okada Y
- Journal Title
  
  J. Biol. Chem
  
  Volume: 282 Pages: 25864-25874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Binding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cells.2007
- Author(s)
  Shimoda M., Hashimoto G., Mochizuki S., Ikeda E., Nagai N., Ishida S., Okada Y.
- Journal Title
  
  J.Biol. Chem. 282
  
  Pages: 25864-25874
- Data Source
  KAKENHI-PROJECT-19109004
[Journal Article] Binding of ADAM 28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leiikocyte adhesion to endothelial cells2007
- Author(s)
  Shimoda M. Hashimoto G., Mochizuki S., Ikeda E., Nagai N., Ishida S., and Okada Y.
- Journal Title
  
  The Journal of Biological Chemistry 282
  
  Pages: 25864-25874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790254
[Journal Article] ADAM28 is overexpressed in human breast carcinomas : implications for carcinoma cell proliferation through cleavage of insulin-like growth factor binding protein-3.2006
- Author(s)
  Mitsui Y, Mochizuki S, Kodama T, Shimoda M, Ohtsuka T, Shiomi T, Chijiiwa M, Ikeda T, Kitajima M, Okada Y
- Journal Title
  
  Cancer Research 66
  
  Pages: 9913-9920
- Data Source
  KAKENHI-PROJECT-18790254
[Patent] 抗ヒト膜型ADAM28抗体2015
- Inventor(s)
  宮越陽、古城周久、岡田保典、望月早月、下田将之
- Industrial Property Rights Holder
  宮越陽、古城周久、岡田保典、望月早月、下田将之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-045244
- Filing Date
  2015-03-06
- Data Source
  KAKENHI-PROJECT-24249022
[Presentation] 組織内微小環境因子代謝を介した腫瘍進展機構の解析2022
- Author(s)
  下田将之
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24116
[Presentation] ワークショップ：がんと微小環境「がん微小環境とメタロプロテアーゼ」2020
- Author(s)
  下田将之
- Organizer
  第109回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07422
[Presentation] HYBIDの変形性関節症関節軟骨での発現とヒアルロン酸分解における役割解析2018
- Author(s)
  清水英徳、下田将之、望月早月、宮前結加、阿部仁、千々岩みゆき、吉田浩之、塩澤淳、石島旨章、金子和夫、金治有彦、中村雅也、戸山芳昭、岡田保典
- Organizer
  第31回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-16H05454
[Presentation] 腫瘍進展におけるADAM（a disintegrin and metalloproteinase）の役割2018
- Author(s)
  下田将之
- Organizer
  第23回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] 内軟骨性骨形成におけるHYBID（hyaluronan-binding protein involved in hyaluronan depolymerization）の機能解析2017
- Author(s)
  下田将之、吉田浩之、水野早希子、弘實透、堀内圭輔、吉野雄太、原英彰、石島旨章、井上紳太郎、金井　弥栄、岡田保典
- Organizer
  第30回日本軟骨代謝学会
- Place of Presentation
  みやこめっせ（京都府京都市）
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] 長管骨形成に関わるHYBID（HYaluronan-Binding protein Involved in hyaluronan Depolymerization）の役割解析2017
- Author(s)
  下田将之、吉田浩之、水野早希子、弘實透、堀内圭輔、吉野雄太、原英彰、金井弥栄、井上紳太郎、石島旨章、岡田保典
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] 組織内微小環境因子代謝を介した腫瘍進展機構に関する研究2017
- Author(s)
  下田将之
- Organizer
  第63回日本病理学会秋期特別総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] HYBID（HYaluronan-Binding protein Involved in hyaluronan Depolymerization）遺伝子欠損マウスの作製と表現型解析2016
- Author(s)
  下田将之、吉田浩之、水野早希子、弘實透、堀内圭輔、吉野雄太、原英彰、石島旨章、井上紳太郎、金井弥栄、岡田保典
- Organizer
  第13回日本病理学会カンファレンス
- Place of Presentation
  六甲山ホテル（兵庫県神戸市）
- Year and Date
  2016-07-29
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] 発育におけるHYBID（HYaluronan-Binding protein Involved in hyaluronan Depolymerization）の機能解析2016
- Author(s)
  下田将之、吉田浩之、水野早希子、弘實透、堀内圭輔、吉野雄太、原英彰、石島旨章、井上紳太郎、金井弥栄、岡田保典
- Organizer
  第46回日本創傷治癒学会
- Place of Presentation
  東京大学内伊藤国際学術研究センター伊藤謝恩ホール・安田講堂（東京都文京区）
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] HYBID（HYaluronan-Binding protein Involved in hyaluronan Depolymerization）遺伝子欠損マウスの作製と表現型解析2016
- Author(s)
  下田将之、吉田浩之、水野早希子、弘實透、堀内圭輔、井上紳太郎、岡田保典
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎大学医学部良順会館・記念講堂（長崎県長崎市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K08719
[Presentation] 病的組織におけるメタロプロテアーゼの機能解析研究2015
- Author(s)
  下田将之
- Organizer
  日本病理学会総会
- Place of Presentation
  名古屋国際会場（愛知県名古屋）
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25860276
[Presentation] 癌間質線維芽細胞形質獲得におけるTIMP分子の機能解析2014
- Author(s)
  下田将之、Rama Khokha
- Organizer
  第103回病理学会総会
- Place of Presentation
  広島
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25860276
[Presentation] Selective inhibition of ADAM28 activity by human anti-ADAM28 antibodies suppresses cancer cell proliferation and metastasis.2013
- Author(s)
  Satsuki Mochizuki, Hitoshi Abe, Masyuki Shimoda, Noriko Aramaki-Hattori, Yuka Miyamae, Akira Miyakoshi, Kanehisa Kojoh and Yasunori Okada
- Organizer
  Pan Pacific Connective Tissue Society Symposium
- Place of Presentation
  Hong Kong.
- Data Source
  KAKENHI-PROJECT-24249022
[Presentation] Induction of ADAM28 in endothelial cells at inflammatory sites enhances leukocyte adhesion to endothelial cells2008
- Author(s)
  Shimoda M, Okada Y
- Organizer
  The XXIth Federation of European Connective Tissue Societies meeting
- Place of Presentation
  Marseille, France
- Data Source
  KAKENHI-PROJECT-20790291
[Presentation] がん細胞-血管内皮細胞接着におけるADAM28の役割解析2008
- Author(s)
  下田将之
- Organizer
  第17回日本がん転移学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-20790291
[Presentation] Induction of ADAM28 in endothelial cells at inflammatory sites enhances leukocyte adhesion to endothelial cells2008
- Author(s)
  Shimoda M, Okada Y
- Organizer
  The XXIth Federation of European Connective Tissue Societies meeting
- Place of Presentation
  Marseille (France)
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20790291
[Presentation] ADAM28の血管内皮細胞による発現と機能解析2008
- Author(s)
  下田将之、岡田保典
- Organizer
  第97回日本病理学会
- Place of Presentation
  金沢
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20790291
[Presentation] 「炎症細胞-血管内皮細胞接着におけるADAM28の役割」(シンポジウム)2007
- Author(s)
  下田将之、橋本学爾、望月早月、池田栄二、岡田保典
- Organizer
  第39回日本結合組織学会学術大会・第54回マトリックス研究会大会合同学術集会
- Place of Presentation
  北とぴあ(東京)
- Year and Date
  2007-05-11
- Data Source
  KAKENHI-PROJECT-18790254
[Presentation] 「炎症細胞の血管外遊走におけるADAM28の役割」(一般口演)2007
- Author(s)
  下田将之、橋本学爾、望月早月、池田栄二、永井紀博、石田晋、岡田保典
- Organizer
  第28回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18790254

1. Ohtsuka Takashi (40306717)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. OKADA Yasunori (00115221)

# of Collaborated Projects: 5 results

# of Collaborated Products: 29 results
3. NISHIMURA Tomoyasu (90348649)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. MOCHIZUKI Satsuki (80365428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
5. 長谷川直樹 (20198724)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. FUJII Yutaka (80211522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. KIMURA Tokuhiro (40445200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SASAKI Aya (60343381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. 浦岡俊夫 (80448216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 佐藤圭吾 (40868626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. IKEDA Eiji (30232177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. ARAMAKI Noriko (80365311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 安樂真樹 (70598557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. デベガスサーナ (30623590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 平澤恵理 (50245718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石島旨章 (70365576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. チレッキメフメット・ゼイネル (10827538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 貴志和生 (40224919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 橋本浩平 (70464964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 柚木俊二 (20399398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 栗林志行 (60726173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 木下智成 (30573406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 高橋祐介 (00445214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 浦野泰照 (20292956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岡潔 (80354661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 竹内洋司 (60728856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 久保健一郎 (20348791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KIRAN Chada

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. JEANINE D' armiento

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KANAI Yae

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
31. SUGIURA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. AKASAKI Yasuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 佐々木光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 田中俊英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 吉田清嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 吉田彩舟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 上野秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 平沢晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 金治有彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 中山淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimoda Masayuki 下田 将之

SHIMODA Masayuki 下田 将之

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個細胞空間的degradome解析に基づくプロテアーゼを介したがん免疫制御の解明Principal Investigator

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Pathological analysis of HYBID-mediated hyaluronic acid metabolism involved in the tumor microenvironment creationPrincipal Investigator

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Analysis of cancer-associated fibroblasts from the perspective of proteinases and epigeneticsPrincipal Investigator

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Comprehensive analysis of metalloproteinases in cancer-associated fibroblastsPrincipal Investigator

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Shimoda Masayuki 下田将之

SHIMODA Masayuki 下田将之

[Book] Cowden病/PTEN過誤腫症候群. 九嶋亮治，牛久哲男編. 腫瘍病理鑑別診断アトラス十二指腸・小腸・虫垂腫瘍2021

[Book] Cronkhite-Canada症候群. 九嶋亮治，牛久哲男編. 腫瘍病理鑑別診断アトラス十二指腸・小腸・虫垂腫瘍2021