Obara Naoshi 小原直

… Alternative Names

OBARA Naoshi 小原直

小原直オバラナオシ

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Researcher Number	70422178
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 筑波大学, 医学医療系, 教授 2017 – 2019: 筑波大学, 医学医療系, 准教授 2016: 筑波大学, 医学医療系, 教授 2013 – 2015: 筑波大学, 医学医療系, 准教授 2011: 筑波大学, 医学医療系, 講師 … More 2011: 筑波大学, 医療医学系, 講師 2010: 筑波大学, 大学院・人間総合科学研究科, 講師 2008: 筑波大, 人間総合科学研究科, 講師 2007: University of Tsukuba, 大学院・人間総合科学研究科, 講師 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 造血不全 / Nestin / 造血支持細胞 / 赤芽球 / マクロファージ / 赤芽球島 / 骨髄異形成症候群 / GFAP / Notchシグナル / エリスロポエチン … More / Nestin陽性細胞 / 網羅的遺伝子解析 / 再生不良性貧血 / aplastic anemia / GFPD / bone marrow failure / 分化障害 / Rbpj / IL-6 / 炎症性貧血 / 造血微小環境 / Notchiシグナル / 血管内皮細胞 / Ｎｏｔｃｈシグナル / Ｎｅｓｔｉｎ / 造血幹細胞 / 赤血球造血 / ストローマ細胞 / エンハンサー / BAC / トランスジェニックマウス / 転写因子 / 腎性貧血 / 組織特異的遺伝子発現 / 低酸素 … More Except Principal Investigator 幹細胞ニッチ / 間葉系幹細胞 / 骨髄繊維症 / 骨髄異形成症候群 / 造血器腫瘍 / 造血ニッチ / 急性骨髄性白血病 / 造血幹細胞 / 造血幹細胞ニッチ / 赤芽球造血 / Notch / Rbpj / NOTCH / nestin / 赤芽球 / 骨髄ストローマ Less

The abnormalities of Haematopoietic supporting cells and impaired erythroblast island formation in bone marrow failure disease.Principal Investigator
- Principal Investigator
  
  Obara Naoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Tsukuba
Analyses of hematopoietic niche in hematologic malignancy
- Principal Investigator
  
  Nishikii Hidekazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Tsukuba
Analysis of neural cell marker-expressing hematopoietic supporting cells in human bone marrow failurePrincipal Investigator
- Principal Investigator
  
  Obara Naoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
Unraveling bone marrow erythropoiesis niche
- Principal Investigator
  
  Chiba Shigeru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
Analysis of Nestin expressing cells in bone marrowPrincipal Investigator
- Principal Investigator
  
  Obara Naoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
The analysis of the hypoxia-induced regulation mechanism in erythropetin gene expression and erythrocytosisPrincipal Investigator
- Principal Investigator
  
  OBARA Naoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
低酸素応答系遺伝子発現における転写制御の解明Principal Investigator
- Principal Investigator
  
  小原直
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba

[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　6）ホルムイミノトランスフェラーゼ欠損症2023
- Author(s)
  小原　直
- Total Pages
  3
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21K08365
[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　3）Imerslund-Graesbeck症候群2023
- Author(s)
  小原　直
- Total Pages
  3
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21K08365
[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　2）若年性悪性貧血2023
- Author(s)
  小原　直
- Total Pages
  3
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21K08365
[Book] 巨赤芽球性貧血2022
- Author(s)
  小原　直
- Total Pages
  367
- Publisher
  日本医師会雑誌
- Data Source
  KAKENHI-PROJECT-21K08365
[Book] 貧血総論と各種貧血へのアプローチ2022
- Author(s)
  小原　直
- Total Pages
  300
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21K08365
[Book] 血液内科2013
- Author(s)
  小原　直
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-25461408
[Book] 血液症候群(第2版)-若年性悪性貧血2013
- Author(s)
  小原　直、二宮　治彦
- Total Pages
  3
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461408
[Book] 血液症候群(第2版)-ホルムイミノトランスフェラーゼ欠損症2013
- Author(s)
  小原　直、二宮　治彦
- Total Pages
  3
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461408
[Book] 血液症候群(第2版)-Imersland-Grasbeck症候群（選択的ビタミンB12吸収不全症）2013
- Author(s)
  小原　直、二宮　治彦
- Total Pages
  2
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25461408
[Journal Article] Durable remission of T-cell prolymphocytic leukemia with CLEC16A::IL2 after allogeneic hematopoietic stem cell transplantation2024
- Author(s)
 百瀬春佳、坂本竜弘、横山泰久、加藤貴康、松岡亮太、小原直、坂田（柳元）麻実子、千葉滋、栗田尚樹、錦井秀和、遊佐希、横山和明、清水英吾、井元清哉、南木融、丸山ゆみ子
- Journal Title
 
 Rinsho Ketsueki
 
 Volume: 65 Issue: 1 Pages: 35-40
- DOI
 10.11406/rinketsu.65.35
- ISSN
 0485-1439, 1882-0824
- Language
 Japanese
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K08365
[Journal Article] A phase 2, open-label study of ibrutinib plus rituximab in Japanese patients with Waldenstrom’s macroglobulinemia2024
- Author(s)
  Izutsu Koji、Kato Hisashi、Sekiguchi Naohiro、Fujisaki Tomoaki、Kawakita Toshiro、Obara Naoshi、Matsue Kosei、Nishimoto Mitsutaka、Hatayama Tomoyoshi、Inagaki Mitsuo、Fujikawa Ei
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 1 Pages: 80-90
- DOI
  10.1007/s12185-024-03761-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Impact of CD34 positive cell dose in donor graft on the outcomes after haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide ? A retrospective single-center study with a Japanese cohort2024
- Author(s)
  Maruyama Yumiko、Nishikii Hidekazu、Kurita Naoki、Sakamoto Tatsuhiro、Hattori Keiichiro、Suehara Yasuhito、Yokoyama Yasuhisa、Kato Takayasu、Obara Naoshi、Sakata-Yanagimoto Mamiko、Chiba Shigeru
- Journal Title
  
  Blood Cells, Molecules, and Diseases
  
  Volume: 105 Pages: 102820-102820
- DOI
  10.1016/j.bcmd.2023.102820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365
[Journal Article] Burden of illness in Japanese patients with paroxysmal nocturnal hemoglobinuria receiving C5 inhibitors2024
- Author(s)
  Obara Naoshi、Usuki Kensuke、Hayashi Takeshi、Fujii Masato、Ikezoe Takayuki
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 3 Pages: 255-264
- DOI
  10.1007/s12185-023-03698-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Repeated immunosuppressive rabbit antithymocyte globulin therapy for adult patients with relapsed or refractory aplastic anemia2023
- Author(s)
  Sakamoto Tatsuhiro、Obara Naoshi、Maruyama Yumiko、Kato Takayasu、Kurita Naoki、Hattori Keiichiro、Suehara Yasuhito、Nishikii Hidekazu、Yokoyama Yasuhisa、Sakata‐Yanagimoto Mamiko、Usuki Kensuke、Chiba Shigeru
- Journal Title
  
  European Journal of Haematology
  
  Volume: 111 Issue: 5 Pages: 768-776
- DOI
  10.1111/ejh.14075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365
[Journal Article] Lymphoplasmacytic lymphoma accompanied by severe myelofibrosis2023
- Author(s)
  宝田亜矢子, 百瀬春佳, 栗田尚樹, 松岡亮太, 中村直哉, 坂本竜弘, 加藤貴康, 服部圭一朗, 末原泰人, 横山泰久, 錦井秀和, 丸山ゆみ子, 小原直, 千葉滋, 坂田（柳元）麻実子
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 1 Pages: 54-59
- DOI
  10.11406/rinketsu.64.54
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16262
[Journal Article] A longitudinal analysis of paroxysmal nocturnal haemoglobinuria‐type cells in patients with bone marrow failure: Results of a prospective multi‐centre study in Japan2023
- Author(s)
  Ishiyama Ken、Yonemura Yuji、Kawaguchi Tatsuya、Hosokawa Kohei、Sugimori Chiharu、Ueda Yasutaka、Takamori Hiroyuki、Obara Naoshi、Noji Hideyoshi、Shirasugi Yukari、Ando Kiyoshi、Shichishima Tsutomu、Ninomiya Haruhiko、Chiba Shigeru、Nishimura Jun‐ichi、Kanakura Yuzuru、Nakao Shinji
- Journal Title
  
  British Journal of Haematology
  
  Volume: 203 Issue: 3 Pages: 468-476
- DOI
  10.1111/bjh.19048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07859, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K08367
[Journal Article] Decision analysis of allogeneic bone marrow transplantation versus immunosuppressive therapy for young adult patients with aplastic anemia2023
- Author(s)
  Kanda Yoshinobu、Usuki Kensuke、Inagaki Mitsuhiro、Ohta Akiko、Ogasawara Yoji、Obara Naoshi、Kako Shinichi、Kurokawa Mineo、Shimada Naoki、Suzuki Takahiro、Hama Asahito、Yamaguchi Hiroki、Nakao Shinji、Yamazaki Hirohito
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 5 Pages: 660-668
- DOI
  10.1007/s12185-022-03530-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Female and preserved platelet count subgroups of myelodysplastic syndrome patients benefit from standard‐dose azacitidine2023
- Author(s)
  Ogawa Shinichi、Sakamoto Tatsuhiro、Matsuoka Ryota、Ishitsuka Kantaro、Ogino Yasuko、Sootome Ayano、Makishima Kenichi、Yoshida Chikashi、Ito Yufu、Shimizu Seiichi、Suyama Takuya、Shinagawa Atsushi、Ito Takayoshi、Obara Naoshi、Kusakabe Manabu、Sakata‐Yanagimoto Mamiko、Miyazaki Yasushi、Nannya Yasuhito、Chiba Shigeru
- Journal Title
  
  Cancer Reports
  
  Volume: 7 Issue: 1
- DOI
  10.1002/cnr2.1938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Interim analysis of post-marketing surveillance of ravulizumab for paroxysmal nocturnal hemoglobinuria in Japan2023
- Author(s)
  Usuki Kensuke、Ikezoe Takayuki、Ishiyama Ken、Kanda Yoshinobu、Gotoh Akihiko、Hayashi Hideo、Shimono Akihiko、Kitajima Akiyo、Obara Naoshi、Nishimura Jun-ichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 3 Pages: 311-322
- DOI
  10.1007/s12185-023-03625-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Waldenström macroglobulinemia complicated by peripheral neuropathy due to neural infiltration2023
- Author(s)
  法岡菜月、高橋華、中馬越清隆、石井亜紀子、松岡亮太、南木融、玉岡晃、千葉滋、栗田尚樹、加村雄哉、坂本竜弘、加藤貴康、横山泰久、錦井秀和、小原直、坂田（柳元）麻実子
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 1 Pages: 18-22
- DOI
  10.11406/rinketsu.64.18
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-22K06064, KAKENHI-PROJECT-21K08365
[Journal Article] The fatty acid elongase Elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation2023
- Author(s)
  Kiyoki Yusuke、Kato Takayasu、Kito Sakura、Matsuzaka Takashi、Morioka Shin、Sasaki Junko、Makishima Kenichi、Sakamoto Tatsuhiro、Nishikii Hidekazu、Obara Naoshi、Sakata-Yanagimoto Mamiko、Sasaki Takehiko、Shimano Hitoshi、Chiba Shigeru
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 4 Pages: 910-913
- DOI
  10.1038/s41375-023-01842-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-20K08724, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H02680, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K27319
[Journal Article] Hematopoietic recovery by ASXL1-mutated clones after immune suppressive therapy in a patient with severe aplastic anemia2023
- Author(s)
 清水百萌、服部圭一朗、丸山ゆみ子、南谷泰仁、小川誠司、坂田（柳元）麻実子、千葉滋、小原直、錦井秀和、飯塚正、松岡亮太、栗田尚樹、坂本竜弘、横山泰久、加藤貴康、末原泰人
- Journal Title
 
 Rinsho Ketsueki
 
 Volume: 64 Issue: 1 Pages: 49-53
- DOI
 10.11406/rinketsu.64.49
- ISSN
 0485-1439, 1882-0824
- Language
 Japanese
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16262
[Journal Article] Safety of romiplostim administered immediately after cord-blood transplantation: a phase 1 trial2023
- Author(s)
  Kurita Naoki、Nishikii Hidekazu、Maruyama Yumiko、Suehara Yasuhito、Hattori Keiichiro、Sakamoto Tatsuhiro、Kato Takayasu、Yokoyama Yasuhisa、Obara Naoshi、Maruo Kazushi、Ohigashi Tomohiro、Yamaguchi Hitomi、Iwamoto Toshiro、Minohara Hideto、Matsuoka Ryota、Hashimoto Koichi、Sakata-Yanagimoto Mamiko、Chiba Shigeru
- Journal Title
  
  Annals of Hematology
  
  Volume: 102 Issue: 10 Pages: 2895-2902
- DOI
  10.1007/s00277-023-05410-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365
[Journal Article] Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria: Long‐term results from the phase I/II COMPOSER trial2023
- Author(s)
  R?th Alexander、Ichikawa Satoshi、Ito Yoshikazu、Kim Jin Seok、Nagy Zsolt、Obara Naoshi、Panse Jens、Schrezenmeier Hubert、Sica Simona、Soret Juliette、Usuki Kensuke、Yoon Sung‐Soo、Balachandran Nadiesh、Buri Muriel、Lundberg Pontus、Patel Himika、Shinomiya Kenji、Sostelly Alexandre、Nishimura Jun‐ichi
- Journal Title
  
  European Journal of Haematology
  
  Volume: 111 Issue: 2 Pages: 300-310
- DOI
  10.1111/ejh.14011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations2023
- Author(s)
  Tsuboi Y, Sakamoto T, Makishima K, Suehara Y, Hattori K, Kurita N, Yokoyama Y, Kato T, Nishikii H, Obara N, Matsumura F, Matsuoka R, Chiba S, Sakata-Yanagimoto M.
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 10 Pages: 1527-1530
- DOI
  10.2169/internalmedicine.0269-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-05-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-23K15316, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16262
[Journal Article] Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion2023
- Author(s)
  Tsuboi Yuri、Iimura Yumoe、Matsumura Fumiaki、Nanmoku Toru、Suma Sakurako、Matsuoka Ryota、、、、、Sato Kimi、Maruyama Yumiko、Sakamoto Tatsuhiro、Yokoyama Yasuhisa、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Obara Naoshi、Ieda Masaki、Chiba Shigeru、Sakata-Yanagimoto Mamiko
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 4 Pages: 595-600
- DOI
  10.2169/internalmedicine.9248-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-02-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16262
[Journal Article] Salvage Cord Blood Transplantation Using a Short-term Reduced-intensity Conditioning Regimen for Graft Failure2022
- Author(s)
  Suma Sakurako、Yokoyama Yasuhisa、Momose Haruka、Makishima Kenichi、Kiyoki Yusuke、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 11 Pages: 1673-1679
- DOI
  10.2169/internalmedicine.7836-21
- NAID
  130008119247
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
[Journal Article] Acute myeloid leukemia harboring NUP98::DDX102022
- Author(s)
 栗田尚樹、坪井宥璃、小原直、錦井秀和、坂田（柳元）麻実子、千葉滋、加藤貴康、南木融、丸山ゆみ子、末原泰人、服部圭一朗、坂本竜弘、横山泰久、吉田近思
- Journal Title
 
 Rinsho Ketsueki
 
 Volume: 63 Issue: 10 Pages: 1397-1401
- DOI
 10.11406/rinketsu.63.1397
- ISSN
 0485-1439, 1882-0824
- Language
 Japanese
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-21K16262
[Journal Article] Dysmegakaryopoiesis and Transient Mild Increase in Bone Marrow Blasts in Patients With Aplastic Anemia Treated With Eltrombopag May Be Signs of Hematologic Improvement and Not Portend Clonal Evolution2022
- Author(s)
  Matsuda Akira、Imada Kazunori、Obara Naoshi、Iida Hiroatsu、Yamazaki Hirohito、Tomiyama Yoshiaki、Miyamura Koichi、Sasaki Osamu、Maeda Tetsuo、Ohta Kensuke、Usuki Kensuke、Tokumine Yukihiro、Imajo Kenji、Okamoto Yuji、Murakami Mami、Nakao Shinji
- Journal Title
  
  American Journal of Clinical Pathology
  
  Volume: 158 Issue: 5 Pages: 604-615
- DOI
  10.1093/ajcp/aqac094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Novel translocation of POGZ/STK11 in de novo mast cell leukemia with KIT D816H mutation2022
- Author(s)
  Ishitsuka Kantaro、Yoshizawa Yuki、Nishikii Hidekazu、Kusakabe Manabu、Ito Yufu、Inadome Yukinori、Sakamoto Tatsuhiro、Kato Takayasu、Kurita Naoki、Yokoyama Yasuhisa、Obara Naoshi、Hasegawa Yuichi、Nannya Yasuhito、Ogawa Seishi、Sakata-Yanagimoto Mamiko、Chiba Shigeru
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 63 Issue: 14 Pages: 3475-3479
- DOI
  10.1080/10428194.2022.2123235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
[Journal Article] Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuria2022
- Author(s)
  Kamura Yuya、Sakamoto Tatsuhiro、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Chiba Shigeru、Obara Naoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 1 Pages: 55-59
- DOI
  10.1007/s12185-022-03387-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
[Journal Article] Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuria2022
- Author(s)
  OBARA Naoshi
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 33 Issue: 5 Pages: 572-575
- DOI
  10.2491/jjsth.33.572
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Administration of brentuximab vedotin to a Hodgkin lymphoma patient with liver dysfunction due to vanishing bile duct syndrome resulting in a partial response without any severe adverse events2022
- Author(s)
  Ishitsuka Kantaro、Yokoyama Yasuhisa、Baba Naoko、Matsuoka Ryota、Sakamoto Noriaki、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 62 Issue: 3 Pages: 154-157
- DOI
  10.3960/jslrt.21035
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Long-term follow-up of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: post-marketing surveillance in Japan2022
- Author(s)
  Ikezoe Takayuki、Noji Hideyoshi、Ueda Yasutaka、Kanda Yoshinobu、Okamoto Shinichiro、Usuki Kensuke、Matsuda Takahisa、Akiyama Hirozumi、Shimono Akihiko、Yonemura Yuji、Kawaguchi Tatsuya、Chiba Shigeru、Kanakura Yuzuru、Nishimura Jun-Ichi、Ninomiya Haruhiko、Obara Naoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 4 Pages: 470-480
- DOI
  10.1007/s12185-022-03287-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08862, KAKENHI-PROJECT-21K08365
[Journal Article] Early administration of cyclosporine may reduce the incidence of cytokine release syndrome after HLA-haploidentical hematopoietic stem-cell transplantation with post-transplant cyclophosphamide2021
- Author(s)
  Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Annals of Hematology
  
  Volume: 100 Issue: 5 Pages: 1295-1301
- DOI
  10.1007/s00277-021-04439-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
[Journal Article] A simple HPLC assay for determining eltrombopag concentration in human serum2021
- Author(s)
  Yanagimachi Naoya、Obara Naoshi、Sakata‐Yanagimoto Mamiko、Chiba Shigeru、Doki Kosuke、Homma Masato
- Journal Title
  
  Biomedical Chromatography
  
  Volume: 35 Issue: 5 Pages: 1-3
- DOI
  10.1002/bmc.5049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-19K07158
[Journal Article] Eltrombopag in Combination with Rabbit Anti-thymocyte Globulin/Cyclosporine A in Immunosuppressive Therapy-naïve Patients with Aplastic Anemia in Japan2021
- Author(s)
  Imada Kazunori、Obara Naoshi、Iida Hiroatsu、Imajo Kenji、Maeda Tetsuo、Usuki Kensuke、Fanghong Zhang、Hombo Yosuke、Tajima Takeshi、Kumagai Akiko、Matsuda Akira、Nakao Shinji
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 8 Pages: 1159-1168
- DOI
  10.2169/internalmedicine.6063-20
- NAID
  130008025054
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] The clinical significance of PNH-phenotype cells accounting for < 0.01% of total granulocytes detected by the Clinical and Laboratory Standards Institute methods in patients with bone marrow failure2021
- Author(s)
 Hosokawa Kohei、Ishiyama Ken、Ikemoto Toshiyuki、Sugimori Chiharu、Noji Hideyoshi、Shichishima Tsutomu、Obara Naoshi、Chiba Shigeru、Ninomiya Haruhiko、Nguyen Mai Anh Thi、Shirasugi Yukari、Nakamura Yoshihiko、Ando Kiyoshi、Ueda Yasutaka et al.
- Journal Title
 
 Annals of Hematology
 
 Volume: 100 Issue: 8 Pages: 1975-1982
- DOI
 10.1007/s00277-020-04314-w
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19K08862, KAKENHI-PROJECT-21K08365
[Journal Article] IgG-variant Bing-Neel syndrome diagnosed by detecting MYD88 L265P mutation in the cerebrospinal fluid cells2021
- Author(s)
 丸山ゆみ子、小原直、中村直哉、千葉滋、錦井秀和、松岡亮太、槇島健一、栗田尚樹、日下部学、横山泰久、加藤貴康、坂田（柳元）麻実子
- Journal Title
 
 Rinsho Ketsueki
 
 Volume: 62 Issue: 10 Pages: 1493-1498
- DOI
 10.11406/rinketsu.62.1493
- NAID
 130008113174
- ISSN
 0485-1439, 1882-0824
- Language
 Japanese
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-20K16165, KAKENHI-PROJECT-21K08365
[Journal Article] Acquired platelet dysfunction with severe bleeding tendency in triple-negative myelofibrosis2021
- Author(s)
  百瀬春佳、加藤貴康、栗田尚樹、五月女礼乃、坂田（柳元）麻実子、小原直、長谷川雄一、小川誠司、千葉滋、錦井秀和、上妻行則、太田（堤）育代、南谷泰仁、吉田近思、米野琢哉、日下部学、横山泰久
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 9 Pages: 1406-1411
- DOI
  10.11406/rinketsu.62.1406
- NAID
  130008101339
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-21K08365
[Journal Article] Overview2021
- Author(s)
  小原直
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 5 Pages: 370-370
- DOI
  10.11406/rinketsu.62.370
- NAID
  130008049795
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08365
[Journal Article] Random Skin Biopsies Before Brain Biopsy for Intravascular Large B-Cell Lymphoma2019
- Author(s)
  Yamada Erika、Ishikawa Eiichi、Watanabe Rei、Matsumura Hideaki、Sakamoto Noriaki、Ishii Akiko、Tamaoka Akira、Hattori Keiichiro、Obara Naoshi、Chiba Shigeru、Nakamagoe Kiyotaka、Matsuda Masahide、Tsurubuchi Takao、Tomidokoro Yasushi、Akutsu Hiroyoshi、Zaboronok Alexander、Shibuya Makoto、Takano Shingo、Matsumura Akira
- Journal Title
  
  World Neurosurgery
  
  Volume: 121 Pages: 364-369
- DOI
  10.1016/j.wneu.2018.09.110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898
[Journal Article] The prognosis of disseminated intravascular coagulation associated with hematologic malignancy and its response to recombinant human thrombomodulin2019
- Author(s)
  Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Thrombosis Research
  
  Volume: 173 Pages: 57-64
- DOI
  10.1016/j.thromres.2018.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946
[Journal Article] Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis2019
- Author(s)
  Cao-Sy Luan、Obara Naoshi、Sakamoto Tatsuhiro、Kato Takayasu、Hattori Keiichiro、Sakashita Shingo、Nannya Yasuhito、Ogawa Seishi、Harada Hironori、Sakata-Yanagimoto Mamiko、Nishikii Hidekazu、Chiba Shigeru
- Journal Title
  
  International Journal of Hematology
  
  Volume: 109 Issue: 3 Pages: 309-318
- DOI
  10.1007/s12185-018-02576-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-18K08316, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656
[Journal Article] Durable Leukemic Remission and Autologous Marrow Recovery with Random Chromosomal Abnormalities after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia2019
- Author(s)
  Nishikii Hidekazu、Kurita Naoki、Shinagawa Atsushi、Sakamoto Tatsuhiro、Kusakabe Manabu、Yokoyama Yasuhisa、Kato Takayasu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Nakamura Naoya、Chiba Shigeru
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 2019 Pages: 1-5
- DOI
  10.1155/2019/9710790
- NAID
  120007128070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09946
[Journal Article] Hematologic recovery induced by eltrombopag in Japanese patients with aplastic anemia refractory or intolerant to immunosuppressive therapy.2019
- Author(s)
  Yamazaki H, Ohta K, Iida H, Imada K, Obara N, Tokumine Y, Tomiyama Y, Usuki K, Imajo K, Miyamura K, Sasaki O, Fanghong Z, Hattori T, Tajima T, Matsuda A, Nakao S.
- Journal Title
  
  Int J Hematol
  
  Volume: 110 Issue: 2 Pages: 187-196
- DOI
  10.1007/s12185-019-02683-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08318, KAKENHI-PROJECT-17K09898
[Journal Article] Notch signaling in Nestin-expressing cells in the bone marrow maintains erythropoiesis via macrophage integrity2019
- Author(s)
  Sakamoto Tatsuhiro、Obara Naoshi、Nishikii Hidekazu、Kato Takayasu、Luan Cao Sy、Fujimura Ryosuke、Yagita Hideo、Sakata-Yanagimoto Mamiko、Takahashi Satoru、Chiba Shigeru
- Journal Title
  
  STEM CELLS
  
  Volume: 印刷中 Issue: 7 Pages: 924-936
- DOI
  10.1002/stem.3011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09915
[Journal Article] Fatal exacerbations of chronic active Epstein-Barr virus infection subsequent to cytotoxic chemotherapy2019
- Author(s)
  Suma S, Kurita N, Baba N, Ishitsuka K, Sukegawa S, Makishima K, Kiyoki Y, Maruyama Y, Kato T, Yokoyama Y, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 4 Pages: 286-290
- DOI
  10.11406/rinketsu.60.286
- NAID
  130007642867
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898
[Journal Article] Successful management of primary immune thrombocytopenia with romiplostim during open heart surgery in a hemodialysis patient2019
- Author(s)
  錦井秀和、栗田尚樹、日下部学、横山泰久、加藤貴康、坂田（柳元）麻実子、小原直、長谷川雄一、千葉滋
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 1 Pages: 28-32
- DOI
  10.11406/rinketsu.60.28
- NAID
  130007590727
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16076
[Journal Article] Genetic evidence implies that primary and relapsed tumors arise from common precursor cells in primary central nervous system lymphoma2018
- Author(s)
  Hattori Keiichiro、Sakata-Yanagimoto Mamiko、Kusakabe Manabu、Nanmoku Toru、Suehara Yasuhito、Matsuoka Ryota、Noguchi Masayuki、Yokoyama Yasuhisa、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Obara Naoshi、Takano Shingo、Ishikawa Eiichi、Matsumura Akira、Muratani Masafumi、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 1 Pages: 401-407
- DOI
  10.1111/cas.13848
- NAID
  120007128280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09946, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-16H02660, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-15H05576
[Journal Article] Blastic plasmacytoid dendritic cell neoplasm accompanied by chronic myelomonocytic leukemia successfully treated with azacitidine2018
- Author(s)
  助川慎一郎、横山泰久、錦井秀和、加藤貴康、日下部学、栗田尚樹、小原直、長谷川雄一、千葉滋、坂田（柳元）麻実子、松岡亮太、百瀬春佳、清木祐介、野口雅之、中村直哉、渡辺玲、藤本学
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 12 Pages: 2567-2573
- DOI
  10.11406/rinketsu.59.2567
- NAID
  130007554669
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16076
[Journal Article] Reference guide for adult chronic neutropenia2018
- Author(s)
  横山泰久、千葉滋、日本医療研究開発機構・難治性疾患実用化研究事業「成人慢性好中球減少症の診療ガイドライン作成に向けた予後追跡調査」研究班、高見昭良、森康雄、佐藤信也、鈴木隆浩、五所正彦、小原直、宮﨑泰司、赤司浩一
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 7 Pages: 845-857
- DOI
  10.11406/rinketsu.59.845
- NAID
  130007430620
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-18K08371, KAKENHI-PROJECT-15K09489
[Journal Article] Relationship between clinical features and somatic gene mutations in myelodysplastic syndrome2018
- Author(s)
  平沢伸広、小川誠司、長谷川雄一、千葉滋、坂田（柳元）麻実子、南谷泰仁、服部圭一郎、末原泰人、加藤貴康、横山泰久、栗田尚樹、小原直
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 1 Pages: 80-83
- DOI
  10.11406/rinketsu.59.80
- NAID
  130006337948
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898
[Journal Article] Establishment of a flow cytometry assay for detecting paroxysmal nocturnal hemoglobinuria-type cells specific to patients with bone marrow failure2018
- Author(s)
  Hosokawa Kohei、Sugimori Chiharu、Ishiyama Ken、Takamatsu Hiroyuki、Noji Hideyoshi、Shichishima Tsutomu、Obara Naoshi、Chiba Shigeru、Ninomiya Haruhiko、Shirasugi Yukari、Nakamura Yoshihiko、Ando Kiyoshi、Ueda Yasutaka、Yonemura Yuji、Kawaguchi Tatsuya、Nishimura Jun-ichi、Kanakura Yuzuru、Nakao Shinji
- Journal Title
  
  Annals of Hematology
  
  Volume: 97 Issue: 12 Pages: 2289-2297
- DOI
  10.1007/s00277-018-3443-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K16184
[Journal Article] Effects of eculizumab treatment on quality of life in patients with paroxysmal nocturnal hemoglobinuria in Japan2018
- Author(s)
  Y. Ueda, N. Obara, Y. Yonemura, H. Noji, M. Masuko, Y. Seki, K. Wada, T. Matsuda, H. Akiyama, T. Ikezoe, S. Chiba, Y. Kanda, T. Kawaguchi, T. Shichishima, H. Nakakuma, S. Okamoto, J. Nishimura, Y. Kanakura, H. Ninomiya
- Journal Title
  
  International Journal of Hematology
  
  Volume: epub Issue: 6 Pages: 1-10
- DOI
  10.1007/s12185-018-2409-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09502, KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09898
[Journal Article] An Unprecedented Case of p190 BCR-ABL Chronic Myeloid Leukemia Diagnosed during Treatment for Multiple Myeloma: A Case Report and Review of the Literature2018
- Author(s)
  Miki Kosuke、Obara Naoshi、Makishima Kenichi、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 2018 Pages: 1-5
- DOI
  10.1155/2018/7863943
- NAID
  120007128268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107
[Journal Article] Liquid biopsy for the identification of intravascular large B-cell lymphoma2018
- Author(s)
  Suehara Yasuhito、Sakata-Yanagimoto Mamiko、et al
- Journal Title
  
  Hematologica
  
  Volume: in press Issue: 6 Pages: e241-e244
- DOI
  10.3324/haematol.2017.178830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15497, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946, KAKENHI-PROJECT-18K07436, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-16H02660
[Journal Article] High efficacy of eculizumab treatment for fulminant hemolytic anemia in primary cold agglutinin disease2018
- Author(s)
  Makishima Kenichi、Obara Naoshi、Ishitsuka Kantaro、Sukegawa Shinichiro、Suma Sakurako、Kiyoki Yusuke、Baba Naoko、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Nishikii Hidekazu、Kurita Naoki、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Annals of Hematology
  
  Volume: 98 Issue: 4 Pages: 1031-1032
- DOI
  10.1007/s00277-018-3521-4
- NAID
  120007128039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898
[Journal Article] A phase I/II trial of intrabone marrow cord blood transplantation and comparison of the hematological recovery with the Japanese nationwide database2017
- Author(s)
  Kurita N, Gosho M, Yokoyama Y, Kato T, Obara N, Sakata-Yanagimoto M, Hasegawa Y, Uchida N, Takahashi S, Kouzai Y, Atsuta Y, Kurata M, Ichinohe T, Chiba S
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 52 Issue: 4 Pages: 574-579
- DOI
  10.1038/bmt.2016.319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19542, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-15K19543
[Journal Article] A single institutional retrospective evaluation for younger patients with primary central nervous lymphomas on a modified R-MPV regimen followed by radiotherapy and high dose cytarabine2017
- Author(s)
  Hattori Keiichiro、Sakata-Yanagimoto Mamiko、Okoshi Yasushi、Kato Takayasu、Kurita Naoki、Yokoyama Yasuhisa、Obara Naoshi、Takano Shingo、Ishikawa Eiichi、Yamamoto Tetsuya、Matsumura Akira、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 57 Issue: 2 Pages: 41-46
- DOI
  10.3960/jslrt.17012
- NAID
  130006854539
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-16K15497
[Journal Article] 再生不良性貧血治療の最前線2017
- Author(s)
  小原　直
- Journal Title
  
  臨床血液
  
  Volume: 58 Pages: 1851-1859
- NAID
  130006132645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898
[Journal Article] Chronic Graft-versus-host Disease Presenting with Multiple Punctate Intracranial Lesions on Contrast-enhanced Magnetic Resonance Imaging2017
- Author(s)
  Terada M, Nakamagoe K, Obara N, Ogawa S, Sakamoto N, Sato T, Nohara S, Chiba S, Tamaoka A.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 3 Pages: 363-368
- DOI
  10.2169/internalmedicine.56.7329
- NAID
  130005310315
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-26460901
[Journal Article] Detection of the circulating tumor DNAs in angioimmunoblastic T- cell lymphoma2017
- Author(s)
  Sakata-Yanagimoto Mamiko、Nakamoto-Matsubara Rie、Komori Daisuke、Nguyen Tran B.、Hattori Keiichiro、Nanmoku Toru、Kato Takayasu、Kurita Naoki、Yokoyama Yasuhisa、Obara Naoshi、Hasegawa Yuichi、Shinagawa Atsushi、Chiba Shigeru
- Journal Title
  
  Annals of hematology
  
  Volume: 96 Issue: 9 Pages: 1471-1475
- DOI
  10.1007/s00277-017-3038-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-16H02660, KAKENHI-PROJECT-16K15497
[Journal Article] Clinical significance of disease-specific MYD88 mutations in circulating DNA in primary central nervous system lymphoma2017
- Author(s)
  Hattori Keiichiro、Sakata-Yanagimoto Mamiko、Suehara Yasuhito、Yokoyama Yasuhisa、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Obara Naoshi、Takano Shingo、Ishikawa Eiichi、Matsumura Akira、Hasegawa Yuichi、Chiba Shigeru
- Journal Title
  
  Cancer science
  
  Volume: 109 Issue: 1 Pages: 225-230
- DOI
  10.1111/cas.13450
- NAID
  120007134545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-16H02660, KAKENHI-PROJECT-15H04947, KAKENHI-PROJECT-16K15497
[Journal Article] A nationwide survey of co-occurrence of malignant lymphomas and myelodysplastic syndromes/myeloproliferative neoplasms.2016
- Author(s)
  Sakata-Yanagimoto M, Yokoyama Y, Muto H, Obara N, Kurita N, Kato T, Hasegawa Y, Miyazaki Y, Kurokawa M, Chiba S
- Journal Title
  
  Annals of Hematology
  
  Volume: 98 Issue: 5 Pages: 829-830
- DOI
  10.1007/s00277-016-2612-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25461407, KAKENHI-PROJECT-15K19543
[Journal Article] Late occurrence of Epstein-Barr virus-associated lymphoproliferative disorder in a patient with follicular lymphoma treated with bendamustine and rituximab.2015
- Author(s)
  Muroi K, Sakata-Yanagimoto M, Sato T, Yokoyama Y, Maie K, Kurita N, Obara N, Hasegawa Y, Noguchi M, Chiba S.
- Journal Title
  
  Annals of Hematology
  
  Volume: 94 Issue: 12 Pages: 2061-2062
- DOI
  10.1007/s00277-015-2463-3
- NAID
  120007134139
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25461407
[Journal Article] Acute painful crisis in a female Nigerian patient with sickle cell disease2015
- Author(s)
  Nin S, Seki M, Maie K, Kuroda A, Miyamoto K, Ogawa S, Ito Y, Kurita N, Yokoyama Y, Sakata Yanagimoto M, Obara N, Hasegawa Y, Ogino Y, Ito T, Chiba S.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 1 Pages: 30-34
- DOI
  10.11406/rinketsu.56.30
- NAID
  130004920690
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461407, KAKENHI-PROJECT-25461408
[Journal Article] Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia.2015
- Author(s)
  Ogawa S, Yokoyama Y, Suzukawa K, Nanmoku T, Kurita N, Seki M, Maie K, Suyama T, Takaiwa N, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
- Journal Title
  
  Annals of Hematology
  
  Volume: 94 Issue: 8 Pages: 1431-1433
- DOI
  10.1007/s00277-015-2391-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25461407
[Journal Article] Multiple myeloma recurring as small intestinal polyposis after autologous hematopoietic stem cell transplantation2015
- Author(s)
  Otsu K, Seki M, Ogawa S, Miyamoto K, Ito Y, Sakata A, Kurita N, Yokoyama Y, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 4 Pages: 400-405
- DOI
  10.11406/rinketsu.56.400
- NAID
  130005069840
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461408
[Journal Article] Complete Remission in Systemic Skin Interdigitating Dendritic Cell Sarcoma after ABVD Chemotherapy2015
- Author(s)
  Kyogoku C, Seki M, Ogawa S, Miyamoto K, Ito Y, Kurita N, Yokoyama Y, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Fujishima F, Ichinohasama R, Nakamura S, Chiba S.
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 55 Issue: 1 Pages: 33-37
- DOI
  10.3960/jslrt.55.33
- NAID
  130005083796
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25461407
[Journal Article] Double somatic mosaic mutations in TET2 and DNMT3A-origin of peripheral T cell lymphoma in a case2015
- Author(s)
  Nguyen TB, Sakata-Yanagimoto M, Nakamoto-Matsubara R, Enami T, Ito Y, Kobayashi T, Obara N, Hasegawa Y, Chiba S
- Journal Title
  
  Annals of Hematology
  
  Volume: EPUB ahead of print Issue: 7 Pages: 1221-1223
- DOI
  10.1007/s00277-015-2332-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670444, KAKENHI-PROJECT-15K15359, KAKENHI-PROJECT-25461408
[Journal Article] Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria.2015
- Author(s)
  Ninomiya H, Obara N, Niiori-Onishi A, Yokoyama Y, Sakata-Yanagimoto M, Hasegawa Y, Chiba S
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 673195 Pages: 1-4
- DOI
  10.1155/2015/673195
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25461407
[Journal Article] Perisurgical induction of eculizumab in a patient with paroxysmal nocturnal hemoglobinuria: its inhibition of surgery-triggered hemolysis and the consequence of subsequent discontinuation2013
- Author(s)
  Kurita N, Obara N, Fukuda K, Nishikii H, Sato S, Inagawa S, Kurokawa T, Owada Y, Ninomiya H, Chiba S
- Journal Title
  
  Blood Coagul Fibrinolysis
  
  Volume: 24 Issue: 6 Pages: 658-662
- DOI
  10.1097/mbc.0b013e328360d057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461408
[Journal Article] Effectiveness and safety of rabbit anti-thymocyte globulin in Japanese patients with aplastic anemia2013
- Author(s)
  Sakamoto T, Obara N, Kurita N, Sakata-Yanagimoto M, Nishikii H, Yokoyama Y, Suzukawa K, Hasegawa Y, Chiba S.
- Journal Title
  
  Int J Hematol.
  
  Volume: 98 Issue: 3 Pages: 319-322
- DOI
  10.1007/s12185-013-1418-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461408
[Journal Article] Acute myeloid leukemia possibly originating from the same clone of testicular germ cell tumor2013
- Author(s)
  Suyama T, Obara N, Kawai K, Yamada K, Kusakabe M, Kurita N, Nishikii H, Yokoyama Y, Suzukawa K, Hasegawa Y, Noguchi M, Chiba S
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 54 Pages: 764-768
- NAID
  10031196294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461408
[Journal Article] Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.2013
- Author(s)
  Kon A, Yoshida K
- Journal Title
  
  Nature Genet.
  
  Volume: 45 Issue: 10 Pages: 1232-1237
- DOI
  10.1038/ng.2731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134003, KAKENHI-PLANNED-22134006, KAKENHI-PROJECT-22221009, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-25290065, KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25670446, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25860521
[Journal Article]2011
- Author(s)
  Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O
- Journal Title
  
  Molecular cell biology
  
  Volume: 31 Issue: 16 Pages: 3298-3331
- DOI
  10.1128/mcb.05310-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790895
[Journal Article] Frequent pathway mutations of splicing machinery in myelodysplasia2011
- Author(s)
  Kenichi Yoshida
- Journal Title
  
  Nature
  
  Volume: 478 Issue: 7367 Pages: 64-69
- DOI
  10.1038/nature10496
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130002, KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-22390191, KAKENHI-PROJECT-22659058, KAKENHI-PROJECT-22790895, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23118503, KAKENHI-PROJECT-23390269, KAKENHI-PROJECT-23659482, KAKENHI-PROJECT-23659533, KAKENHI-PROJECT-23791068, KAKENHI-PROJECT-23791075
[Journal Article] Nine years interval between first and second bone marrow transplantations and subsequent long-term survival-a case of acute myeloid leukemia with MLL-AF6 fusion gene2011
- Author(s)
  Yokoyama Y, Suzukawa K, Okoshi Y, Nanmoku T, Obara N, Enami T, Hasegawa Y, Chiba S
- Journal Title
  
  Annals of Hematology
  
  Volume: 91 Issue: 9 Pages: 1491-1493
- DOI
  10.1007/s00277-012-1417-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790895
[Journal Article] Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages2011
- Author(s)
  Suzuki N, Obara N, Pan X, Watanabe M, Jishage K-i, Minegishi N, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 18 Pages: 3896-3905
- DOI
  10.1128/mcb.05463-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22790895
[Journal Article] 巨赤芽球性貧血2010
- Author(s)
  小原直、二宮治彦
- Journal Title
  
  治療
  
  Volume: 92 Pages: 2333-2338
- Data Source
  KAKENHI-PROJECT-22790895
[Journal Article] Detection of the STAT5B-RARA fusion transcript in acute promyelocytic leukemia with the normal chromosome 17 on G-banding.2008
- Author(s)
  Kusakabe M, Suzukawa K, Nanmoku T, Obara N, Okoshi Y, Mukai HY, Hasegawa Y, Kojima H, Kawakami Y, Ninomiya H, Nagasawa T.
- Journal Title
  
  Eur J Haematol. 80
  
  Pages: 444-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790658
[Journal Article] Repression via the GATA bos is essential for tissue-specific erythropoietin geneexpression.2008
- Author(s)
  Obara N, Suzuki N, Kim K, Imagawa S, Nagasawa T, Yamamoto M.
- Journal Title
  
  Blood (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790658
[Journal Article] Myelodysplastic syndrome accompanied by basophilia and eosinophilia with t(5;12)(q31:p13).2007
- Author(s)
  Katsura Y, Suzukawa K, Nanmoku T, Nemoto N, Machino T, Obara N, Okoshi Y, Mukai HY, Hasegawa Y, Kojima H, Nagasawa T.
- Journal Title
  
  Cancer Genet Cytogenet. 178
  
  Pages: 85-88
- NAID
  120007139117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790658
[Journal Article] Use of gene-manipulated mice in the study of erythropoietin gene expression.2007
- Author(s)
  Suzuki N, Obara N, Yamamoto M.
- Journal Title
  
  Methods Enzymol. 435
  
  Pages: 157-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790658
[Presentation] ATRAによる横紋筋融解症が疑われた一例2023
- Author(s)
  上原惇; 服部圭一朗; 末原泰人; 佐々木裕哉; 横山泰久; 小原直ら
- Organizer
  日本内科学会ことはじめ2023
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] BTK 阻害薬が著効した脳神経障害を有する再発難治 MYD88 変異陽性 B 細胞リンパ腫2023
- Author(s)
  上原惇; 錦井秀和; 末原泰人; 服部圭一朗; 佐々木裕哉; 丸山ゆみ子; 坂本竜弘; 加藤貴康; 栗田尚樹; 横山泰久; 小原
- Organizer
  第18回日本血液学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 再生不良性貧血患者の血清ビリルビン測定に及ぼす血中エルトロンボパグ濃度の干渉2023
- Author(s)
  小田　峻; 土岐浩介; 鈴木嘉治; 小原　直; 千葉　滋; 本間真人
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] The burden of illness of patients with PNH receiving complement inhibitors: PRO study in Japan2023
- Author(s)
  Naoshi Obara; Kensuke Usuki; Takeshi Hayashi; Masato Fujii et al
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] Pegcetacoplan improves D-dimer normalization and decreases incidence of thrombosis in PNH patients2023
- Author(s)
  Hisakazu Nishimori; Kensuke Usuki; Naoshi Obara et al.
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] Real-World Treatment Patterns, Outcomes and Disease Burden of Japanese Patients with High-Risk Myelodysplastic Syndrome: A Claims Database Study2023
- Author(s)
  Obara Naoshi; Shioi Hirotomo; Ooi Shi Hong et al.
- Organizer
  64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 再生不良性貧血に対するウサギATGを用いた２度目の免疫抑制療法についての検討2022
- Author(s)
  坂本竜弘; 小原直; 加藤貴康; 栗田尚樹; 日下部学; 横山泰久; 錦井秀和; 坂田(柳元)麻実子; 臼杵憲祐; 千葉滋
- Organizer
  第119回日本内科学会総会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 白血病環境由来の TNFa は造血幹細胞の巨核球バイアスを促進する2022
- Author(s)
  錦井秀和; 斎藤美月; 木村隆治; 清木祐介; 加藤貴康; 坂本竜弘; 坂田(柳元)麻実子; 小原直; 山﨑　聡; 千葉滋
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 同種造血幹細胞移植後に発症した肝類洞閉塞症候群 24 例に対する治療の後方視的検討2022
- Author(s)
  宝田亜矢子; 栗田尚樹; 丸山ゆみ子; 末原泰人; 服部圭一朗; 坂本竜弘; 加藤貴康; 横山泰久; 錦井秀和; 小原直; 坂田(...
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 多発性骨髄腫に対する同種移植後のレナリドミド維持療法の至適投与量の検討2022
- Author(s)
  河村浩二; 塚田信弘; 木村俊一; 賀古真一; 皆方大佑; 榎並輝和; 浜埜康晴; 内田直之; 太田秀一; 小原直; 安藤潔;
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -2021
- Author(s)
  Yasutaka Ueda, Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
- Organizer
  63rd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] "COMPOSER Part 4: an optimized dosing strategy for crovalimab in patients with PNH"2021
- Author(s)
  Naoshi Obara, Regis Peffault de Latour，Simona Sica，Julia Ramos，Jules Hernandez-Sanchez，Jin Seok Kim，Anna Kiialainen，Sung-Soo Yoon，Sasha Sreckovic，Antoine Soubret，Alexandre Sostelly，Jens Panse，Simon Buatois，Hubert Schrezenmeier，Ido Paz-Priel，Alexander Roeth，Jun-ichi Nishimura
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] 腫瘍細胞の神経浸潤による末梢神経障害を合併した原発性マクログロブリン血症2021
- Author(s)
  法岡菜月, 栗田尚樹，加村雄哉，日下部学，坂本竜弘，加藤貴康，横山泰久，錦井秀和，坂田（柳元）麻実子，小原　直，高橋　華，中馬越清隆，石井亜紀子，松岡亮太，玉岡　晃，千葉　滋
- Organizer
  第15回日本血液学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] Repeated immunosuppressive therapy using rabbit anti-thymocyte globulin for aplastic anemia2021
- Author(s)
  Tatsuhiro Sakamoto, Naoshi Obara，Takayasu Kato，Naoki Kurita，Manabu Kusakabe，Yasuhisa Yokoyama，Hidekazu Nishikii，Mamiko Sakata-Yanagimoto，Kensuke Usuki，Shigeru Chiba
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08365
[Presentation] Notch signaling in nestin-expressing bone marrow stromal cells supports erythropoietic niche2019
- Author(s)
  Tatsuhiro Sakamoto、Naoshi Obara, Hidekazu Nishikii, Takayasu Kato, Cao Sy Luan, Ryosuke Fujimura, Mamiko Sakata-Yanagimoto, Satoru Takahashi, Shigeru Chiba
- Organizer
  The 10th JSH INTERNATIONAL SYMPOSIUM 2019 in Ise-Shima
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 地固め療法中に骨髄壊死を認めたフィラデルフィア染色体陽性急性リンパ芽球性白血病、地固め療法中に骨髄壊死を認めたフィラデルフィア染色体陽性急性リンパ芽球性白血病2019
- Author(s)
  石塚幹太郎, 小原　直，坂本　竜弘，加藤　貴康，日下部　学，栗田　尚樹，横山　泰久，錦井　秀和，坂田（柳元）麻実子，長谷川　雄一，千葉　滋
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] The relationship between the pretreatment PNH clone size and clinical course in patients with bone marrow failure syndromes: Interim analysis of Japanese multicenter prospective study2019
- Author(s)
  asutaka Ueda、Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Hiroshi Takahashi, Yukari Shirasugi, Takahisa Matsuda, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
- Organizer
  The 24th Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] ブスルファン投与に伴う幻覚の解析2019
- Author(s)
  栗田　尚樹, 坂本　竜弘，加藤　貴康，日下部　学，横山　泰久，錦井　秀和，坂田（柳元）麻実子，小原直，長谷川　雄一，千葉滋
- Organizer
  第41回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] Distinct Schwann cell abnormalities in MDS and MPN bone marrow with fibrosis2019
- Author(s)
  Luan Cao-Sy, Yoshiaki Takahoko, Naoshi Obara, Tatsuhiro Sakamoto, Takayasu Kato, Keiichiro Hattori, Ryota Matsuoka, Shingo Sakashita, Yasuhito Nannya, Hideki Makishima, Seishi Ogawa, Mamiko Sakata-Yanagimoto, Hidekazu Nishikii, Shigeru Chiba
- Organizer
  日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08316
[Presentation] 後天性血小板機能異常により顕著な出血傾向を呈し，急速な経過を辿った原発性骨髄線維症の1例2019
- Author(s)
  百瀬春佳、錦井　秀和，上妻　行則，堤（太田）育代，吉田　近思，米野　琢哉，助川　慎一郎，石塚　幹太郎，槇島　健一，日下部　学，横山　泰久，加藤　貴康，栗田　尚樹，坂田（柳元）麻実子，小原　直，長谷川　雄一，千葉　滋
- Organizer
  第10回日本血液学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 特発性血小板減少性紫斑病患者における血清エルトロンボパグ濃度が肝障害発現に及ぼす影響2019
- Author(s)
  柳町　直哉、小原直, 横山　泰久, 錦井　秀和, 坂田（柳元）麻実子, 長谷川　雄一, 大越靖, 千葉滋, 土岐　浩介, 本間　真人
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] Distinct bone marrow microenvironment abnormalities in MDS and MPN with fibrosis2019
- Author(s)
  Luan Cao-Sy, Yoshiaki Takahoko, Naoshi Obara, Tatsuhiro Sakamoto, Takayasu Kato, Keiichiro Hattori, Ryota Matsuoka, Shingo Sakashita, Yasuhito Nannya, Hideki Makishima, Seishi Ogawa, Mamiko Sakata-Yanagimoto, Hidekazu Nishikii, Shigeru Chiba
- Organizer
  Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08316
[Presentation] Targeting T-cell receptor signaling pathway by dasatinib in relapsed/refractory angioimmunoblastic T-cell lymphoma2019
- Author(s)
  usuke Kiyoki、Mamiko Sakata-Yanagimoto, Tran B. Nguyen, Manabu Fujisawa, Yasuhito Nanya, Kantaro Ishitsuka, Haruka Momose, Shinichiro Sukegawa, Atsushi Shinagawa, Takuya Suyama, Yuji Sato, Hidekazu Nishikii, Naoshi Obara et al.
- Organizer
  The 24th Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] Targeted sequencing and IgH rearrangement status revealed branching evolution pattern of SMZL and DLBCL2019
- Author(s)
  Manabu Kusakabe、Mamiko Sakata-Yanagimoto, Yasuhito Suehara, Keiichiro Hattori, Toru Nanmoku, Tatsuhiro Sakamoto, Yasuhisa Yokoyama, Takayasu Kato, Naoki Kurita, Hidekazu Nishikii, Naoshi Obara, Masafumi Muratani, Yuichi Hasegawa, Shigeru Chiba
- Organizer
  The 10th JSH INTERNATIONAL SYMPOSIUM 2019 in Ise-Shima
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 生着不全に対するmodified 1-day regimenを用いた臍帯血移植の検討2018
- Author(s)
  須摩桜子、横山泰久，石塚幹太郎，助川慎一郎，槇島健一，清木祐介，馬場直子，坂本竜弘，日下部学，加藤貴康，錦井秀和，栗田尚樹，坂田（柳元）麻実子，小原直，長谷川雄一，千葉滋
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] Bone Marrow Erythropoiesis is Maintained by Notch Signaling in Specific Bone Marrow2018
- Author(s)
  Tatsuhiro Sakamoto, Naoshi Obara, Hidekazu Nishikii, Takayasu Kato, Ryosuke Fujimura, Cao Sy Luan, Mamiko Sakata- Yanagimoto, Satoru Takahashi, Shigeru Chiba
- Organizer
  The 9th JSH International Symposium 2018 in Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 成人慢性好中球減少症の予後追跡調査2018
- Author(s)
  横山泰久, 小原　直，五所正彦，鈴木隆浩，高見昭良，宮崎泰司，赤司浩一，千葉　滋
- Organizer
  第115回　日本内科学会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] エクリズマブ（ソリリス）製造販売後調査（発作性夜間ヘモグロビン尿症）に関する長期観察の中間報告2018
- Author(s)
  野地秀義, 植田康敬, 小原直, 神田善伸, 岡本真一郎, 臼杵憲祐, 松田貴久, 秋山仁泉, 高橋正典, 米村雄士, 川口辰哉, 西村純一, 池添隆之, 千葉滋, 金倉譲, 二宮治彦
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 骨髄破壊的前処置を用いたHLA半合致移植の第I/II相研究2018
- Author(s)
  栗田尚樹、横山泰久，坂本竜弘，加藤貴康，日下部学，錦井秀和，坂田（柳元）麻実子，小原直，小川晋一，周山卓也，馬場直子，長谷川雄一，千葉滋
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] "TP53 mutations found in the serum of malignant lymphoma patients at remission derive from clonal hematopoiesis rather than minimal residual disease. "2018
- Author(s)
  Yasuhito Suehara, Mamiko Sakata-Yanagimoto, Keiichiro Hattori, Taiki Sato, Masayuki Noguchi, Tatsuhiro Sakamoto, Manabu Kusakabe, Naoki Kurita, Takayasu Kato, Yasuhisa Yokoyama, Hidekazu Nishikii, Naoshi Obara, Yuichi Hasegawa, Shigeru Chiba
- Organizer
  2018 ASH Meeting on Lymphoma Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 造血幹細胞移植における入院期間と医療費の検討2018
- Author(s)
  栗田尚樹, 坂本竜弘，加藤貴康，日下部学，錦井秀和，横山泰久，坂田（柳元）麻実子，小原　直，長谷川雄一，千葉　滋
- Organizer
  第115回　日本内科学会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 原発性寒冷凝集素症の溶血発作に対してエクリズマズが著効した一例2018
- Author(s)
  槇島健一, 小原直, 石塚幹太郎, 助川慎一郎, 須摩桜子, 清木祐介, 馬場直子, 坂本竜弘, 日下部学, 加藤貴康, 錦井秀和, 栗田尚樹, 横山泰久, 坂田（柳元）麻実子, 長谷川雄一, 千葉滋
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 同種移植後10年以上経過したのちに再発を認めた成人T細胞白血病／リンパ腫2018
- Author(s)
  助川慎一郎, 横山泰久，石塚幹太郎，百瀬春佳，須摩桜子，清木祐介，馬場直子，真家絋一郎，坂本竜弘，日下部学，錦井秀和，加藤貴康，栗田尚樹，坂田（柳元）麻実子，小原　直，長谷川雄一，千葉　滋
- Organizer
  第8回日本血液学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 再生不良性貧血に対する2回目の免疫抑制療法の単施設における経験2018
- Author(s)
  坂本竜弘, 小原直, 加藤貴康, 栗田尚樹, 日下部学, 錦井秀和, 坂田（柳元）麻実子, 長谷川雄一, 千葉滋
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] 成人慢性好中球減少症の診療に関する全国調査 -第2報-2018
- Author(s)
  横山泰久, 小原直, 五所正彦, 鈴木隆浩, 高見昭良, 宮崎泰司, 赤司浩一, 千葉滋
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09898
[Presentation] Abnormal Increase in a Distinct Subset of Nestin-Expressing Cells in the Bone Marrow of Myelodysplastic Syndromes.2016
- Author(s)
  Luan Cao Sy, Naoshi Obara, Tatsuhiro Sakamoto, Takayasu Kato, Hidekazu Nishikii, Mamiko Sakata-Yanagimoto, Shigeru Chiba.
- Organizer
  The American Society of Hematology 58th Annual Meeting and Exposition
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] Localization of distinct subsets of nestin-expressing cells in human bone marrow and their abnormalities in myelodysplastic syndromes2016
- Author(s)
  Luan Cao Sy, Naoshi Obara, Tatsuhiro Sakamoto, Takayasu Kato, Hidekazu Nishikii, Satoshi Ikeda, Keiko Suzuki, Shigeru Chiba.
- Organizer
  The 14th Stem Cell Research Symposium
- Place of Presentation
  淡路夢舞台（兵庫県淡路市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] Localization and Characteristic of Nestin-expressing Cells in Human Bone Marrow and Their Abnormalities in Myelodysplastic Syndromes.2016
- Author(s)
  Luan Cao Sy, Naoshi Obara, Tatsuhiro Sakamoto, Takayasu Kato, Hidekazu Nishikii, Satoshi Ikeda, Keiko Suzuki, Shigeru Chiba.
- Organizer
  The 5th JCA-AACR Special Joint Conference
- Place of Presentation
  ヒルトン東京ベイ（千葉県浦安市）
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] NOTCH signaling in bone marrow nestin-expressing cells is involved in regulating erythropoiesis.2016
- Author(s)
  坂本竜弘，小原　直，藤村亮介，加藤貴康，Luan Cao Sy，錦井秀和，坂田（柳元）麻実子，高橋　智，千葉　滋.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] Notch Signaling in Bone Marrow Nestin-Expressing Cells Controls Balance of Erythropoiesis at the Bone Marrow and Spleen.2016
- Author(s)
  Tatsuhiro Sakamoto, Naoshi Obara, Takayasu Kato, Luan Cao Sy, Hidekazu Nishikii, Mamiko Sakata-Yanagimoto, Satoru Takahashi, Shigeru Chiba.
- Organizer
  The American Society of Hematology 58th Annual Meeting and Exposition
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] Abnormalities in nestin-expressing bone marrow stromal cells in myelodysplastic syndromes2015
- Author(s)
  NAOSHI OBARA
- Organizer
  International Society for Experimental Hematology 44th Annual Scientific Meeting
- Place of Presentation
  京都l国際会館
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] Abnormalities in nestin-expressing bone marrow stromal cells in myelodysplastic syndromes2015
- Author(s)
  NAOSHI OBARA
- Organizer
  The 6th JSH International Symposium 2015
- Place of Presentation
  軽井沢プリンスホテル
- Year and Date
  2015-05-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] Abnormalities in nestin-expressing bone marrow stromal cells in myelodysplastic syndromes2015
- Author(s)
  Naoshi Obara
- Organizer
  JSH国際シンポジウム
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] Abnormalities in nestin-expressing bone marrow stromal cells in MDS patients2015
- Author(s)
  Noshi Obara，Tatsuhiro Sakamoto，Luan Cao Sy，Takayasu Kato，Sachie Suzuki，Naoki Kurita，Yasuhisa Yokoyama，Mamiko Sakata，Yuichi Hasegawa，Shigeru Chiba.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂、ANAクラウンプラザホテル金沢、ホテル日航金沢、ホテル金沢、金沢市アートホール、もてなしドーム
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K15359
[Presentation] Localization of nestin-expressing cells in bone marrow and the role of Notch signaling in nestin-expressing stromal cells in hematopoiesis2014
- Author(s)
  Naoshi Obara
- Organizer
  日本血液学会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] The OPTIMA update: baseline assessment of PNH-type cells in patients with bone marrow failure2013
- Author(s)
  Yuji Yonemura, Tatsuya Kawaguchi, Kohei Hosokawa, Chiharu Sugimori, Masaki Yamamoto, Naoshi Obara, Hideyoshi Noji, Yoshihiko Nakamura, Kiyoshi Ando, Tsutomu Shichishima, Haruhiko Ninomiya, Shigeru Chiba, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
- Organizer
  日本血学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] Baseline assessment of PNH-type cells in patients with bone marrow failure (The OPTIMA study)2013
- Author(s)
  Naoshi Obara, Shigeru Chiba, Kohei Hosokawa, Chiharu Sugimori, Masaki Yamamoto, Hideyoshi Noji, Yuji Yonemura, Yoshihiko Nakamura, Kiyoshi Ando, Tatsuya Kawaguchi, Tsutomu Shichishima, Haruhiko Ninomiya, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
- Organizer
  アメリカ血液学会
- Place of Presentation
  ニューオーリンズ
- Data Source
  KAKENHI-PROJECT-25461408
[Presentation] Acute panmyelosis with myelofibrosisに対し同種造血幹細胞が有用であった1例2011
- Author(s)
  松原理絵, 小原直, 坂本竜弘, 福田匡芳, 越野繭子, 栗田尚樹, 錦井秀和, 横山泰久, 坂田-柳元麻実子, 大越靖, 鈴川和己, 長谷川雄一, 千葉滋
- Organizer
  第165回日本血液学会例会
- Place of Presentation
  東京
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] 静注Busulfn/Cyclophosphamideを移植前処置に用いた同種造血幹細胞移植11例の検討2011
- Author(s)
  栗田尚樹, 大越靖, 福田匡芳, 松原理絵, 坂本竜弘, 錦井秀和, 横山泰久, 坂田麻実子, 小原直, 鈴川和己, 長谷川雄一, 千葉滋
- Organizer
  日本造血幹細胞移植学会
- Place of Presentation
  松山
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] 発症から8年経過し再発後の治療が奏功しているT細胞性中枢神経原発2011
- Author(s)
  真家紘一郎、鈴川和己、坂本竜弘、福田匡芳、日下部学、鈴木幸恵、栗田尚樹、錦井秀和、横山泰久、小原直、大越靖、長谷川雄一、千葉滋
- Organizer
  第166回日本血液学会例会
- Place of Presentation
  東京
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Outcomes of splenectomy for adult patients with ITP-a single center retrospective analysis2011
- Author(s)
  Yasushi Okoshi, Naoki Kurita, Hidekazu Nishikii, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Naoshi Obara, Kazumi Suzukawa, Yuichi Hasegawa, Shigeru Chiba
- Organizer
  日本血液学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Effect and safety of rabbit anti-thymocyte globulin (ATG)for aplastic anemia2011
- Author(s)
  Tatsuhiro Sakamoto, Naoshi Obara, Rie Matsubara, Kuniyoshi Fukuda, Mayuko Koshino, Naoski Kurita, Hedekazu Nishikii, Yasuhisa Yokoyama, Mamiko Sakata, Yasuhi Okoshi, Kazumi Suzukawa, Yuichi Hasegawa, Shigeru Chiba
- Organizer
  日本血液学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Detection of CD55-and CD59-negative immature reticulocytes may improves sensitivity/specificity to identify a minor population of PNH-type cells in patients with myelodysplastic syndrome/aplastic anemia2011
- Author(s)
  小原直、佐藤晶子、千葉滋、二宮治彦
- Organizer
  第2回JSH国際シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Effect and safety of rabbit anti-thymocyte globulin (ATG) for aplastic anemia2011
- Author(s)
  Tatsuhiro Sakamoto, Naoshi Obara, RieMatsubara, Kuniyoshi Fukuda, MayukoKoshino, Naoski Kurita, Hedekazu Nishikii, Yasuhisa Yokoyama, Mamiko Sakata, YasuhiOkoshi, Kazumi Suzukawa, Yuichi Hasegawa, Shigeru Chiba
- Organizer
  日本血液学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Adverse effecs of intravenous morphine and fentanyl for stomatitis in patients receiving allogenic HCT a single center retrospective analysis2011
- Author(s)
  越野繭子, 大越靖, 坂本竜弘, 福田匡芳, 松原理絵, 栗田尚樹, 錦井秀和, 横山泰久, 坂田麻実子, 小原直, 鈴川和己, 長谷川雄一, 千葉滋
- Organizer
  日本造血幹細胞移植学会
- Place of Presentation
  松山
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Detection of CD55-and CD59-negative immature reticulocytes may improves sensitivity/specificity to identify aminor population of PNH-type cells in patients with myelodysplastic syndrome/aplastic anemia2011
- Author(s)
  小原直, 佐藤晶子, 千葉滋, 二宮治彦
- Organizer
  第2回JSH国際シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] 静注Busulfanによる前処置後の移植後胃前庭部毛細血管拡張症2011
- Author(s)
  福田匡芳, 栗田尚樹, 坂本竜弘, 錦井秀和, 横山泰久, 坂田-柳元麻実子, 小原直, 大越靖, 鈴川和己, 長谷川雄一, 千葉滋
- Organizer
  日本血液学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Who le exome analysis of myelodysplastic syndromes using next-generation reseq uencing technology2010
- Author(s)
  Kenichi Yoshida, Masashi Sanada, Yasunobu Nagata, Ryouichiro Kawahata, Motohiro Kato, Aiko Matsubara, Junko Takita, Hirano Mori, Ken Ishiyama, Taka yuki Ishikawa, Shuichi Miyawaki, Naoshi Obara, Shigeru Chiba, Seishi Ogawa
- Organizer
  The American So ciety of Hematology 52nd Annual Meeting
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Characterization of co-repressor complex DRED in globin gene expression2010
- Author(s)
  Naoshi Obara, Katarzyna Kolodziej, Osamu Tanabe, Flank Grosveld, John Stroubolius, James Douglas Engel
- Organizer
  The 1st JSH International Symposium 2010
- Place of Presentation
  Akita
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Dentification of components of globin gene repressor, DRED2010
- Author(s)
  Naoshi Obara, Katarzyna Kolodziej, Osamu Tanabe, Flank Grosveld, John Stroubolius, James Douglas Engel
- Organizer
  日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Retrospective analysis of BCL2+DLBCL in the rituximab era : multi-center analysis2010
- Author(s)
  Hidekazu Nishikii, Naoya Nakamura, Yuzuru Kondou, Minoru Kojima, Jun Takizawa, Yuichi Hasegawa, Yasushi Okoshi, Kazumi Suzukawa, Yasuhisa Yokoyama, Naoshi Obara, Mamko Sakata-Yanagimoto, Masayuki Noguchi, Sadao Aoki, Kiyoshi Andou, Shigeru Chiba
- Organizer
  日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] Profiling of mul tiple gene mutations in myelodysplasti c syndromes using high-throughput reseq uenceing combined with barcode labeling2010
- Author(s)
  Yasunobu Nagata, Masashi Sanada, Kenichi Yoshida, Takeo Nakaya, Aiko Matsubara, Naoshi Obara, Ken Ishiyama Shuichi Miyawaki, Junko Takita, Shigeru Chiba, Lee-Yung Shih, H Phillip Koeffler, Seishi Ogawa
- Organizer
  The American Society of Hematology 52nd Annual Meeting
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22790895
[Presentation] tT5;12)(q31;p13)を有し好酸球増多と好塩基球増多を伴ったMDSの1症例2007
- Author(s)
  桂行孝・鈴川和己・南木融・根本範子・町野孝幸・小原直・大越靖・向井陽美・長谷川雄一・小島寛川上・康二宮・治彦・長澤俊郎
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  東京
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19790658
[Presentation] 組織球性壊死性リンパ節炎および血球食食症候群を合併したマイコプラズマ肺炎の一例2007
- Author(s)
  越野繭子・向井陽美・武藤秀治・小原直・大越靖・鈴川和己・長谷川雄一・小島寛
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  東京
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19790658
[Presentation] 腎臓におけるエリスロポエチン遺伝子発現制御機構の解析2007
- Author(s)
  佐藤智咲・鈴木教郎・小原直・山嵜瞬・潘小青・今川重彦・山本雅之
- Organizer
  第16回腎とエリスロポエチン研究会
- Place of Presentation
  東京
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19790658
[Presentation] 2-オキソグルタル酸投与による腫瘍血管新生抑制効果2007
- Author(s)
  松本健・今川重彦・小原直・鈴木教郎・長澤俊郎・山本雅之
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19790658
[Presentation] 血中サイトカインを用いた鼻型NK/H細胞リンパ腫の予後・病態解析2007
- Author(s)
  小原直・大越靖・鈴川和己・向井陽美・長谷川雄一・小島寛・長澤俊郎
- Organizer
  第69回日本血液学会・第49回目本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19790658

1. Nishikii Hidekazu (30512834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Chiba Shigeru (60212049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 加藤貴康 (20646591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 日下部学 (40804381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 横山泰久 (70512820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKAMOTO Tatsuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. Luan Cao Sy

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. KURITA Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. NISHIMURA Jun-Ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. YAMAZAKI Hirohito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. SUZUKI Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. SUZUKI Takafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 服部圭一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 植田康敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
15. 金倉譲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 坂田麻実子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 峯岸直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Obara Naoshi 小原 直

OBARA Naoshi 小原 直

小原 直 オバラ ナオシ

Research Projects

Research Products

Co-Researchers

The abnormalities of Haematopoietic supporting cells and impaired erythroblast island formation in bone marrow failure disease.Principal Investigator

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Analyses of hematopoietic niche in hematologic malignancy

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Analysis of neural cell marker-expressing hematopoietic supporting cells in human bone marrow failurePrincipal Investigator

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Unraveling bone marrow erythropoiesis niche

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Analysis of Nestin expressing cells in bone marrowPrincipal Investigator

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The analysis of the hypoxia-induced regulation mechanism in erythropetin gene expression and erythrocytosisPrincipal Investigator

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低酸素応答系遺伝子発現における転写制御の解明Principal Investigator

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[Book] 別冊血液症候群I 血液症候群(第3版) 1.貧血 （3）巨赤芽球性貧血 6）ホルムイミノトランスフェラーゼ欠損症2023

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Total Pages

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[Book] 別冊血液症候群I 血液症候群(第3版) 1.貧血 （3）巨赤芽球性貧血 3）Imerslund-Graesbeck症候群2023

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[Book] 別冊血液症候群I 血液症候群(第3版) 1.貧血 （3）巨赤芽球性貧血 2）若年性悪性貧血2023

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[Book] 巨赤芽球性貧血2022

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[Book] 貧血総論と各種貧血へのアプローチ2022

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[Book] 血液内科2013

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[Book] 血液症候群(第2版)-若年性悪性貧血2013

Author(s)

Obara Naoshi 小原直

OBARA Naoshi 小原直

小原直オバラナオシ

[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　6）ホルムイミノトランスフェラーゼ欠損症2023

[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　3）Imerslund-Graesbeck症候群2023

[Book] 別冊血液症候群I 血液症候群(第3版)　1.貧血　（3）巨赤芽球性貧血　2）若年性悪性貧血2023