suzuki keisuke 鈴木啓介

… Alternative Names

鈴木啓介スズキケイスケ

Less

Researcher Number	70635408
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立長寿医療研究センター, 病院先端医療開発推進センター, センター長
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人国立長寿医療研究センター, 病院先端医療開発推進センター, センター長 2017 – 2019: 国立研究開発法人国立長寿医療研究センター, 治験・臨床研究推進センター, 部長 2012: 名古屋大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Except Principal Investigator Basic Section 58010:Medical management and medical sociology-related / Radiation science / Biological Sciences
Keywords	Except Principal Investigator 研究倫理 / 高齢者 / 同意能力評価 / 同意能力 / インフォームド・コンセント / MIRD法 / 被曝線量 / アルツハイマー病 / タウ蛋白 / アルツハイマー … More / PET / 陽電子断層撮像法 / マイクロドーズ試験 / イソプロテレノール / 神経変性 / CGRP-1 / 運動ニューロン疾患 / 筋萎縮性側索硬化 / アンドロゲン受容体 / サイクリン依存性キナーゼ / TGF-β / サーキット変性 / レンチウイルスベクター / ポリグルタミン / heat shock factor-1 / 熱ショック蛋白質 / TGF-beta / 細胞周期 / ミトコンドリア / 酸化ストレス / 骨格筋 / 球脊髄性筋萎縮症 / 筋萎縮性側索硬化症 / 運動ニューロン / 神経変性疾患 Less

高齢者対象の臨床研究における同意能力評価ガイドライン実装に向けた研究
- Principal Investigator
  
  脇之薗真理
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Fujita Health University
PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementia
- Principal Investigator
  
  Ito Kengo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Center for Geriatrics and Gerontology
Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseases
- Principal Investigator
  
  KATSUNO Masahisa
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University

All 2023 2020 2019 2018 2017 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents2020
- Author(s)
  Ogata Aya、Kimura Yasuyuki、Ikenuma Hiroshi、Yamada Takashi、Abe Junichiro、Koyama Hiroko、Suzuki Masaaki、Ichise Masanori、Kato Takashi、Ito Kengo
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: － Pages: 52-58
- DOI
  10.1016/j.nucmedbio.2020.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
[Journal Article] Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone2019
- Author(s)
  Ikenuma Hiroshi、Koyama Hiroko、Kajino Naoya、Kimura Yasuyuki、Ogata Aya、Abe Junichiro、Kawasumi Yasuhiro、Kato Takashi、Takashima Akihiko、Ito Kengo、Suzuki Masaaki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 16 Pages: 2107-2111
- DOI
  10.1016/j.bmcl.2019.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
[Journal Article] Schwann cell involvement in the peripheral neuropathy of spinocerebellar ataxia type 3.2014
- Author(s)
  Suga N, Katsuno M, Koike H, Banno H, Suzuki K, Hashizume A, Mano T, Iijima M, Kawagashira Y, Hirayama M, Nakamura T, Watanabe H, Tanaka F, Sobue G
- Journal Title
  
  Neuropathol Appl Neurobiol.
  
  Volume: 40 Issue: 5 Pages: 628-639
- DOI
  10.1111/nan.12055
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670445
[Journal Article] Brugada syndrome in spinal and bulbar muscular atrophy.2014
- Author(s)
  Araki A, Katsuno M, Suzuki K, Banno H, Suga N, Hashizume A, Mano T, Hijikata Y, Nakatsuji H, Watanabe H, Yamamoto M, Makiyama T, Ohno S, Fukuyama M, Morimoto S, Horie M, Sobue G
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 20 Pages: 1813-1821
- DOI
  10.1212/wnl.0000000000000434
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25461054, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PLANNED-26117002
[Journal Article] Tongue pressure as a novel biomarker of spinal and bulbar muscular atrophy (SBMA)2014
- Author(s)
  Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Watanabe H, Tanaka S, Yamamoto M, Sobue G
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 3 Pages: 255-262
- DOI
  10.1212/wnl.0000000000000041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
[Journal Article] Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.2013
- Author(s)
  Tanaka S, Banno H, Katsuno M, Suzuki K, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Adachi H, Tatsumi H, Yamamoto M, Sobue G.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 337 Issue: 1-2 Pages: 193-200
- DOI
  10.1016/j.jns.2013.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005
[Journal Article] Differential change of clinical outcome measures in spinal and bulbar muscular atrophy: comparison of natural history with placebo-treated group.2012
- Author(s)
  Hashizume A, Katsuno M, Banno H, Suzuki K, Suga N, Tanaka F, Sobue G.
- Journal Title
  
  J Neurol.
  
  Volume: 259 Issue: 4 Pages: 712-719
- DOI
  10.1007/s00415-011-6251-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986
[Journal Article] Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials.2012
- Author(s)
  Hama T, Hirayama M, Hara T, Nakamura T, Atsuta N, Banno H, Suzuki K, Katsuno M, Tanaka F, Sobue G.
- Journal Title
  
  Muscle Nerve
  
  Volume: 45 Issue: 2 Pages: 169-174
- DOI
  10.1002/mus.22291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-21600003, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24500458
[Journal Article] Molecular pathophysiology and disease-Modifying therapies for spinal and bulbar muscular atrophy2012
- Author(s)
  Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
- Journal Title
  
  Arch Neurol
  
  Volume: 69 Issue: 4 Pages: 436-440
- DOI
  10.1001/archneurol.2011.2308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
[Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2010
- Author(s)
  Banno H, Katsuno M, Suzuki K, Sobue G.
- Journal Title
  
  Lancet Neurol.
  
  Volume: 10 Pages: 113-115
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010
- Author(s)
  Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  Current Mol Med.
  
  Volume: 11 Pages: 48-56
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010
- Author(s)
  Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 81 Pages: 567-571
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010
- Author(s)
  Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
- Journal Title
  
  Lancet Neurol.
  
  Volume: 9 Pages: 875-884
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  J Neurosci.
  
  Volume: 30 Pages: 5702-5707
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 歳を重ねても自分らしく生き延びるための意思決定～同意能力評価と意思決定支援～2023
- Author(s)
  脇之薗真理,飯島祥彦,鈴木啓介,村井はるか
- Organizer
  日本生命倫理学会第35回年次大会
- Data Source
  KAKENHI-PROJECT-23K09637
[Presentation] Formulation of 11C-labeled (R,S)-isoproterenol and pharmacokinetic studies in rats.2019
- Author(s)
  Ikenuma H, Ogata A, Kimura Y, Koyama H, Abe J, Yamada T, Ichise M, Kato T, Suzuki M, Ito K
- Organizer
  Brain & Brain PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Improved (R,S)-[11C]isoproterenol formulation toward clinical study2019
- Author(s)
  池沼宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣綾、山田貴史、加藤隆司、伊藤健吾、鈴木正昭
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Synthesis of 11C-Labeled (R,S)-Isoproterenol and Preclinical PET Study2018
- Author(s)
  Ikenuma H, Koyama H, Kajino N, Kimura Y, Ogata A, Abe J, Kawasumi Y, Kato T, Suzuki M, Ito K
- Organizer
  The World Molecular Imaging Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Synthesis of highly-qualified 11C-labeled (R,S)-isoproterenol aimed at a clinical study2017
- Author(s)
  Ikenuma H, Koyama H, Kimura Y, Abe J, Kawasumi K, Ogata A, Kato T, Ito K, Suzuki M.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 臨床研究を目的とした11C標識化(R,S)-イソプロテレノールの高効率合成法の開発2017
- Author(s)
  池沼　宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣　綾、加藤隆司、伊藤健吾、鈴木正昭
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 認知症治療薬としてのイソプロテレノールの小動物PETを用いたラット脳内移行性の検討2017
- Author(s)
  小縣　綾、木村泰之、池沼　宏、古山浩子、関千江、山田貴史、鈴木正昭、加藤隆司、伊藤健吾
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Brain penetration of isoproterenol as a drug of dementia measured in rats with a micro-PET2017
- Author(s)
  Ogata A, Kimura Y, Ikenuma H, Koyama H, Seki C, Yamada T, Suzuki M, Kato T, Ito K.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 球脊髄性筋萎縮症における細胞周期異常2011
- Author(s)
  勝野雅央, 足立弘明, 南山誠, 土井英樹, 近藤直英, 松本慎二郎, 宮崎雄, 坂野晴彦, 鈴木啓介, 田中章景, 祖父江元
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Central motor conduction time (CMCT) in patients with spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Suzuki K, Katsuno M, Banno H, Suga N, Hashizume A, Hara T, Hama T, Nakamura T, Hirayama M, Tanaka F, Sobue G
- Organizer
  15th Congress of the European Federation of Neurological Societies
- Place of Presentation
  Budapest, Hungary
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Long-term effects of the luteinizing hormone-releasing hormone analogues for spinal and bulbar muscular atrophy2011
- Author(s)
  Ota K, Ishikawa K, Suzuki K, Banno H, Katsuno M, Sobue G, Mizusawa H
- Organizer
  63rd American Academy of Neurology Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Effect of leuprorelin in patients with spinal and bulbar muscular atrophy (SBMA) : a multicenter, randomized, double-blind, placebo-controlled trial2011
- Author(s)
  Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group
- Organizer
  63rd American Academy of Neurology Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 球脊髄性筋萎縮症(SBMA)におけるナトリウムチャンネルの発現異常2010
- Author(s)
  勝野雅央、足立弘明、南山誠、土井英樹、近藤直英、松本慎二郎、坂野晴彦、鈴木啓介、田中章景、祖父江元
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Matsumoto S, Miyazaki Y, Banno H, Suzuki K, Tanaka F, Sobue G.
- Organizer
  21st International Symposium on ALS/MND.
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PLANNED-22110005

1. KATSUNO Masahisa (50402566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
2. SOBUE Gen (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. ADACHI Hiroaki (40432257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. Ito Kengo (70184653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 木村泰之 (20423171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. 関千江 (40443080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 古山浩子 (50402160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. 山田貴史 (50531860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 加藤隆司 (60242864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. 鈴木正昭 (90093046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. 脇之薗真理 (60773843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 村井はるか (90647893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 飯島祥彦 (50584679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TANAKA Fumiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
15. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

suzuki keisuke 鈴木 啓介

鈴木 啓介 スズキ ケイスケ

Research Projects

Research Products

Co-Researchers

高齢者対象の臨床研究における同意能力評価ガイドライン実装に向けた研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Schwann cell involvement in the peripheral neuropathy of spinocerebellar ataxia type 3.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brugada syndrome in spinal and bulbar muscular atrophy.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tongue pressure as a novel biomarker of spinal and bulbar muscular atrophy (SBMA)2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential change of clinical outcome measures in spinal and bulbar muscular atrophy: comparison of natural history with placebo-treated group.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular pathophysiology and disease-Modifying therapies for spinal and bulbar muscular atrophy2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2010

Author(s)

Journal Title

Data Source

[Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010

Author(s)

Journal Title

Data Source

[Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010

Author(s)

Journal Title

Data Source

suzuki keisuke 鈴木啓介

鈴木啓介スズキケイスケ