KIOKA HIDETAKA 木岡秀隆

… Alternative Names

Kioka Hidetaka 木岡秀隆

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Researcher Number	70642099
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2024 – 2025: 大阪大学, 大学院医学系研究科, 助教 2022: 大阪大学, 大学院医学系研究科, 助教 2016 – 2021: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 寄付講座助教 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 寄附講座助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine
Keywords	Principal Investigator イメージング / エネルギー代謝 / 心不全 / 低酸素 / ATP / ミトコンドリア / プロテオミクス / ストレス応答 / 翻訳後修飾 / 創薬 … More / 心筋症 / 生体イメージング / プレコンディショニング / エネルギーー代謝 / 心筋虚血 … More Except Principal Investigator 心筋症 / ゲノム / 心不全 / ゲノム医療 / 心筋不全 / 分子標的医薬品 / ミオシンATP分解酵素 / ATP合成酵素 / エネルギー代謝 / 新規治療法開発 / 新規治療薬開発 / 創薬 / オミックス / 創薬開発 / 創薬治療法開発 / オミックス研究 / ゲノムデータベース構築 / HLA / 心臓サルコイドーシス / サルコイドーシス / 貧血 / ヘモグロビン / マイクロチャネル / 変形能 / 赤血球 Less

時空間代謝イメージングによる心筋リバースリモデリングの本質解明と治療開発Principal Investigator
- Principal Investigator
  
  木岡秀隆
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Osaka
Identification of therapeutic targets for heart failure and development of intervention methods related to the control mechanism of cardiac pump function
- Principal Investigator
  
  高島成二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Stratification of myocardial failure and development of genomic medicine
- Principal Investigator
  
  坂田泰史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Elucidation of a neddylation dependent stress response in cardiomyocytes and drug discoveryPrincipal Investigator
- Principal Investigator
  
  木岡秀隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Establishment of in vivo imaging and research for novel heart failure therapy targeting metabolismPrincipal Investigator
- Principal Investigator
  
  Kioka Hidetaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Identification of Novel Molecular Targets and Drug Development by Genomic and Multilayer-Omics Analysis of Hereditary Cardiomyopathies
- Principal Investigator
  
  Asano Yoshihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Evaluation for genetic predisposition and clinical pathological stratification in cardiac sarcoidosis
- Principal Investigator
  
  Minamiguchi Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Elucidation of the molecular mechanism of cardiac energy metabolism for the development of novel therapy for heart failurePrincipal Investigator
- Principal Investigator
  
  Kioka Hidetaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Analyzing qualitative abnormality of red blood cell for investigating pathophysiology of heart failure
- Principal Investigator
  
  Ohtani Tomohito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
The role of mitochondrial protein MENT in myocardial ischemic preconditioningPrincipal Investigator
- Principal Investigator
  
  Kioka Hidetaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Creatine Chemical Exchange Saturation Transfer (Cr-CEST) Imaging Can Evaluate Cisplatin-induced Testicular Damage2023
- Author(s)
  Kuribayashi Sohei、Saito Shigeyoshi、Sawaya Reika、Takahashi Yusuke、Kioka Hidetaka、Takezawa Kentaro、Kiuchi Hiroshi、Fukuhara Shinichiro、Nonomura Norio
- Journal Title
  
  MRMS
  
  Volume: 22 Issue: 3 Pages: 345-351
- DOI
  10.2463/mrms.mp.2021-0125
- ISSN
  1347-3182, 1880-2206
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-23K15117
[Journal Article] Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity2023
- Author(s)
  Kuribayashi Sohei、Fukuhara Shinichiro、Tsujimura Go、Imanaka Takahiro、Okada Koichi、Ueda Norichika、Takezawa Kentaro、Kiuchi Hiroshi、Saito Shigeyoshi、Takahashi Yusuke、Kioka Hidetaka、Oura Seiya、Shimada Keisuke、Ikawa Masahito、Nonomura Norio
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 22 Issue: 1 Pages: 1-9
- DOI
  10.1002/rmb2.12507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-23K15117, KAKENHI-PROJECT-19K08172
[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022
- Author(s)
  Tabata Tomoka、Kuramoto Yuki、Ohtani Tomohito、Miyawaki Hiroshi、Miyashita Yohei、Sera Fusako、Kioka Hidetaka、Higo Shuichiro、Asano Yoshihiro、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 13 Pages: 1987-1993
- DOI
  10.2169/internalmedicine.8594-21
- NAID
  130008130223
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-23K24328, KAKENHI-PROJECT-19H03652
[Journal Article] Pathophysiological evaluations of initial plaque development after heart transplantation via serial multimodality imaging and cytokine assessments2022
- Author(s)
  Shiraki Tatsuya、Ichibori Yasuhiro、Ohtani Tomohito、Mizote Isamu、Kioka Hidetaka、Tsukamoto Yasumasa、Nakamura Daisuke、Yokoi Kensuke、Ide Seiko、Nakamoto Kei、Takeda Yasuharu、Kotani Jun-ichi、Hikoso Shungo、Sawa Yoshiki、Sakata Yasushi
- Journal Title
  
  The Journal of Heart and Lung Transplantation
  
  Volume: 41 Issue: 7 Pages: 877-885
- DOI
  10.1016/j.healun.2022.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08155
[Journal Article] Loss-of-function mutations in the co-chaperone protein BAG5 cause dilated cardiomyopathy requiring heart transplantation2022
- Author(s)
  Hakui Hideyuki、Kioka Hidetaka、Miyashita Yohei、Nishimura Shunsuke、Matsuoka Ken、Kato Hisakazu、Tsukamoto Osamu、（3人省略）、Saito Shigeyoshi、Ohta Kunio、Asanuma Hiroshi、Fu Hai Ying、Shinomiya Haruki、Yamada Noriaki、Ohtani Tomohito、Sawa Yoshiki、Kitakaze Masafumi、Takashima Seiji、Sakata Yasushi、Asano Yoshihiro
- Journal Title
  
  Science Translational Medicine
  
  Volume: 14 Issue: 628
- DOI
  10.1126/scitranslmed.abf3274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-19H03652
[Journal Article] Refractory Ventricular Arrhythmias in a Patient With Dilated Cardiomyopathy Caused by a Nonsense Mutation in <i>BAG5</i>2022
- Author(s)
  Hakui Hideyuki、Kioka Hidetaka、Sera Fusako、Nakamoto Kei、Ozu Kentaro、Kuramoto Yuki、Miyashita Yohei、Ohtani Tomohito、Hikoso Shungo、Asano Yoshihiro、Sakata Yasushi
- Journal Title
  
  Circ J
  
  Volume: 86 Issue: 12 Pages: 2043
- DOI
  10.1253/circj.CJ-22-0329
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-22K20919, KAKENHI-PROJECT-23K24328
[Journal Article] The CR9 element is a novel mechanical load‐responsive enhancer that regulates natriuretic peptide genes expression2021
- Author(s)
  Miyashita Y, Tsukamoto O, Matsuoka K, Kamikubo K, Kuramoto Y, Fu HY, Tsubota T, Hasuike H, Takayama T, Ito H, Hitsumoto T, Okamoto C, Kioka H, Oya R, Shinomiya H, Hakui H, Shintani Y, Kato H, Kitakaze M, Sakata Y, Asano Y, Takashima S
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 4
- DOI
  10.1096/fj.202002111rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-20K17151, KAKENHI-PROJECT-19H03652
[Journal Article] Cardiac Fibroblasts Play Pathogenic Roles in Idiopathic Restrictive Cardiomyopathy2021
- Author(s)
  Tsuru Hirofumi、Ishida Hidekazu、Narita Jun、Ishii Ryo、Suginobe Hidehiro、Ishii Yoichiro、Wang Renjie、Kogaki Shigetoyo、Taira Masaki、Ueno Takayoshi、Miyashita Yohei、Kioka Hidetaka、Asano Yoshihiro、Sawa Yoshiki、Ozono Keiichi
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 5 Pages: 677-686
- DOI
  10.1253/circj.CJ-20-1008
- NAID
  130008028981
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-04-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07789, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K17561, KAKENHI-PROJECT-19H03652
[Journal Article] Visualization of Spatial Distribution of Spermatogenesis in Mouse Testes Using Creatine Chemical Exchange Saturation Transfer Imaging2021
- Author(s)
  Takahashi Yusuke、Kioka Hidetaka、Fukuhara Shinichiro、Kuribayashi Sohei、Saito Shigeyoshi、Asano Yoshihiro、Takashima Seiji、Yoshioka Yoshichika、Sakata Yasushi
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 54 Issue: 5 Pages: 1457-1465
- DOI
  10.1002/jmri.27734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-19H03652
[Journal Article] Visualization of Spatial Distribution of Spermatogenesis in Mouse Testes Using Creatine Chemical Exchange Saturation Transfer (CrCEST) Imaging.2021
- Author(s)
  Takahashi Y, Kioka H, Saito S, Fukuhara S, Asano Y, Takashima S, Yoshioka Y, Sakata Y.
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: in-press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03652
[Journal Article] Focal severe decrease in myocardial technetium-99 m sestamibi uptake indicates ventricular irreversibility in patients with dilated cardiomyopathy2021
- Author(s)
  Chimura Misato、Ohtani Tomohito、Sera Fusako、Nakamoto Kei、Konishi Shozo、Miyawaki Hiroshi、Kajitani Kenji、Higuchi Rie、Kioka Hidetaka、Hikoso Shungo、Tomiyama Noriyuki、Sakata Yasushi
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 35 Issue: 8 Pages: 881-888
- DOI
  10.1007/s12149-021-01625-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-21K16056
[Journal Article] Dynamic Nature of Nodular Calcification in Cardiac Allograft Vasculopathy2021
- Author(s)
  Kiyose Yuji、Shiraki Tatsuya、Mizote Isamu、Nakamura Daisuke、Tsukamoto Yasumasa、Yokoi Kensuke、Kioka Hidetaka、Ohtani Tomohito、Hikoso Shungo、Minami Shigeru、Sakata Yasushi
- Journal Title
  
  JACC: Cardiovascular Interventions
  
  Volume: 14 Issue: 12 Pages: 1378-1380
- DOI
  10.1016/j.jcin.2021.03.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08581
[Journal Article] In vivo real‐time ATP imaging in zebrafish hearts reveals G0s2 induces ischemic tolerance2020
- Author(s)
  Kioka Hidetaka、Kato Hisakazu、Fujita Takeshi、Asano Yoshihiro、Shintani Yasunori、Yamazaki Satoru、Tsukamoto Osamu、Imamura Hiromi、Kogo Mikihiko、Kitakaze Masafumi、Sakata Yasushi、Takashima Seiji
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 2 Pages: 2041-2054
- DOI
  10.1096/fj.201901686r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP‐1702020
- Author(s)
  Yashirogi Shohei、Nagao Takemasa、Nishida Yuya、Takahashi Yusuke、Qaqorh Tasneem、Yazawa Issei、Katayama Toru、Kioka Hidetaka、Matsui Tsubasa S、Saito Shigeyoshi、Masumura Yuki、Tsukamoto Osamu、Kato Hisakazu、Ueda Hiromichi、Yamaguchi Osamu、Yashiro Kenta、Yamazaki Satoru、Takashima Seiji、Shintani Yasunori
- Journal Title
  
  EMBO reports
  
  Volume: 22 Issue: 1
- DOI
  10.15252/embr.202050949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-21K15443
[Journal Article] Accurate Estimation of the Duration of Testicular Ischemia Using Creatine Chemical Exchange Saturation Transfer ( CrCEST ) Imaging2020
- Author(s)
  Takahashi Yusuke、Kioka Hidetaka、Saito Shigeyoshi、Fukuhara Shinichiro、Asano Yoshihiro、Takashima Seiji、Yoshioka Yoshichika、Sakata Yasushi
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 53 Issue: 5 Pages: 1559-1567
- DOI
  10.1002/jmri.27456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-19H03652
[Journal Article] Higd1a improves respiratory function in the models of mitochondrial disorder2019
- Author(s)
  Nagao Takemasa、Shintani Yasunori、Hayashi Takaharu、Kioka Hidetaka、Kato Hisakazu、Nishida Yuya、Yamazaki Satoru、Tsukamoto Osamu、Yashirogi Shohei、Yazawa Issei、Asano Yoshihiro、Shinzawa‐Itoh Kyoko、Imamura Hiromi、Suzuki Takeo、Suzuki Tsutomu、Goto Yu‐ichi、Takashima Seiji
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 1859-1871
- DOI
  10.1096/fj.201800389r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-17H03646, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] Detection of increased intracerebral lactate in a mouse model of Leigh syndrome using proton MR spectroscopy2019
- Author(s)
  Takahashi Yusuke、Kioka Hidetaka、Shintani Yasunori、Ohki Akiko、Takashima Seiji、Sakata Yasushi、Higuchi Takahiro、Saito Shigeyoshi
- Journal Title
  
  Magnetic Resonance Imaging
  
  Volume: 58 Pages: 38-43
- DOI
  10.1016/j.mri.2019.01.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09017, KAKENHI-PROJECT-16K09501, KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-15K21774
[Journal Article] Mouse skeletal muscle creatine chemical exchange saturation transfer (CrCEST) imaging at 11.7T MRI2019
- Author(s)
  Takahashi Yusuke、Saito Shigeyoshi、Kioka Hidetaka、Araki Rikita、Asano Yoshihiro、Takashima Seiji、Sakata Yasushi、Yoshioka Yoshichika
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 51 Issue: 2 Pages: 563-570
- DOI
  10.1002/jmri.26844
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-15K21774, KAKENHI-PROJECT-19K08172
[Journal Article] A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G0/G1 switch gene 22019
- Author(s)
  Kamikubo Kenta、Kato Hisakazu、Kioka Hidetaka、Yamazaki Satoru、Tsukamoto Osamu、Nishida Yuya、Asano Yoshihiro、Imamura Hiromi、Kawahara Hiroyuki、Shintani Yasunori、Takashima Seiji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 40 Pages: 14562-14573
- DOI
  10.1074/jbc.ra119.008544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K09408, KAKENHI-PUBLICLY-19H05293, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-17H03657, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] Liver Stiffness Reflecting Right-Sided Filling Pressure Can Predict Adverse Outcomes in Patients With Heart Failure.2018
- Author(s)
  Taniguchi T, Ohtani T, Kioka H, Tsukamoto Y, Onishi T, Nakamoto K, Katsimichas T, Sengoku K, Chimura M, Hashimoto H, Yamaguchi O, Sawa Y, Sakata Y.
- Journal Title
  
  JACC Cardiovasc Imaging.
  
  Volume: - Issue: 6 Pages: 955-964
- DOI
  10.1016/j.jcmg.2017.10.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09501
[Journal Article] Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota2018
- Author(s)
  Katsimichas T, Ohtani T, Motooka D, Tsukamoto Y, Kioka H, Nakamoto K, Konishi S, Chimura M, Sengoku K, Miyawaki H, Sakaguchi T, Okumura R, Theofilis K, Iida T, Takeda K, Nakamura S, Sakata Y.
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 6 Pages: 1640-1650
- DOI
  10.1253/circj.CJ-17-1285
- NAID
  130006744246
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-05-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09501, KAKENHI-PROJECT-16K09433, KAKENHI-PROJECT-16K09933
[Journal Article] Successful treatment of severe combined post- and pre- capillary pulmonary hypertension in a patient with idiopathic restrictive cardiomyopathy.2018
- Author(s)
  S. Ishihara, H. Kioka, T. Ohtani, Y. Asano, O. Yamaguchi, S. Hikoso, K. Toda, Y. Saito, Y. Sawa, K. Yamauchi-Takihara, Y. Sakata
- Journal Title
  
  Pulm Circ
  
  Volume: 8 Issue: 3 Pages: 1-5
- DOI
  10.1177/2045894018770131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01712, KAKENHI-PROJECT-16K09501, KAKENHI-PROJECT-18K19547
[Journal Article] Clinical Significance of Pulmonary Arterial Capacitance Calculated by Echocardiography in Patients With Advanced Heart Failure2017
- Author(s)
  Saito Y, Ohtani T, Kioka H, Onishi T, Tsukamoto Y, Nakamoto K, Taniguchi T, Nakatani S, Hirayama A, Sakata Y.
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 12 Pages: 1871-1878
- DOI
  10.1253/circj.CJ-16-1318
- NAID
  130006219112
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09501
[Journal Article] Interferon Therapy Exacerbated Pulmonary Hypertension in a Patient with Hepatitis C Virus Infection: Pathogenic Interplay among Multiple Risk Factors2017
- Author(s)
  Tsuchiya H, Kioka H, Ozu K, Ohtani T, Yamaguchi O, Yazaki Y, Yamauchi-Takihara K, Sakata Y.
- Journal Title
  
  Internal Medicine
  
  Volume: 印刷中
- NAID
  130005632048
- Data Source
  KAKENHI-PROJECT-16K09501
[Journal Article] Cardiogenic shock caused by left mid-ventricular obstruction in a patient with anorexia nervosa; A novel cardiac manifestation of refeeding syndrome.2017
- Author(s)
  Sakamoto Y, Kioka H, Hashimoto R, Takeda S, Ohtani T, Yamaguchi O, Wasa M, Nakatani S, Sakata Y.
- Journal Title
  
  Nutrition
  
  Volume: 35 Pages: 148-150
- DOI
  10.1016/j.nut.2016.12.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16H06950, KAKENHI-PROJECT-16K09501
[Journal Article] A Development of Nucleic Chromatin Measurements as a New Prognostic Marker for Severe Chronic Heart Failure.2016
- Author(s)
  1.M. Kanzaki, Y. Asano, H. Ishibashi-Ueda, E, Oiki, T. Nishida, H. Asanuma, H. Kato, Y. Oka, T. Ohtani, O. Tsukamoto, S. Higo, H. Kioka, K. Matsuoka, Y. Sawa, I. Komuro, M. Kitakaze, S. Takashima, Y. Sakata.
- Journal Title
  
  PLoS One.
  
  Volume: 11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860559
[Journal Article] Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.2016
- Author(s)
  Masumura Y, Higo S, Asano Y, Kato H, Yan Y, Ishino S, Tsukamoto O, Kioka H, Hayashi T, Shintani Y, Yamazaki S, Minamino T, Kitakaze M, Komuro I, Takashima S, Sakata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 28592-28592
- DOI
  10.1038/srep28592
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15K08271, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-16K09501
[Journal Article] Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5.2015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 6137-6137
- DOI
  10.1038/ncomms7137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-25461119
[Journal Article] Higdla is a oositive regulaator of cytochrome c oxidase2015
- Author(s)
  T. Hayashi, Y. Asano, Y. Shintani, H. Aoyama, H. Kioka, O. Tsukamoto, M. Hikita, K. Shinzawa-Itoh, K. Takajuji, S. Higo, H. Kato, S. Yamazaki, K. Matsuoka, A. Nakano, H. Asanuma, M. Asakura, T. Minamino, Y. Goto, T. Ogura, M. Kitakaze, I. Komuro, Y. Sakata, T. Tsukihara, S. Yoshikawa, S. Takashima
- Journal Title
  
  Proc. Nat. Acad. Sci. U.S.A.
  
  Volume: 112 Issue: 5 Pages: 1553-1558
- DOI
  10.1073/pnas.1419767112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PUBLICLY-25109540, KAKENHI-PROJECT-25860599, KAKENHI-PUBLICLY-26104532, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26670402, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-25461119
[Journal Article] Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2.2014
- Author(s)
  Shintani Y, Drexler HC, Kioka H, Terracciano CM, Coppen SR, Imamura H, Akao M, Nakai J, Wheeler AP, Higo S, Nakayama H, Takashima S, Yashiro K, Suzuki K.
- Journal Title
  
  EMBO Reports
  
  Volume: 15 Issue: 4 Pages: 438-445
- DOI
  10.1002/embr.201337945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390212, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25111703, KAKENHI-PROJECT-25461346, KAKENHI-PROJECT-25670387, KAKENHI-PUBLICLY-26115504, KAKENHI-PROJECT-26291027, KAKENHI-PROJECT-26560456, KAKENHI-PROJECT-26860559
[Journal Article] Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart.2014
- Author(s)
  Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S.
- Journal Title
  
  FASEB J.
  
  Volume: 28(4) Issue: 4 Pages: 1870-9
- DOI
  10.1096/fj.13-245522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25118709, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26860559
[Patent] Cr-CEST-MRIを用いた精巣機能の部位別診断法2021
- Inventor(s)
  木岡秀隆
- Industrial Property Rights Holder
  木岡秀隆
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K08581
[Patent] 心不全感受性エンハンサーを含む遺伝子治療用ベクター2020
- Inventor(s)
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Holder
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-206823
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03652
[Patent] Cr-CEST-MRIを用いた精巣機能の部位別診断法2020
- Inventor(s)
  木岡秀隆
- Industrial Property Rights Holder
  木岡秀隆
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K08581
[Patent] 心不全感受性エンハンサーを含む遺伝子治療用ベクター2019
- Inventor(s)
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Holder
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-206823
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Identification of a Novel Causative Gene for Dilated Cardiomyopathy andFuture Therapeutic Strategies2022
- Author(s)
  木岡秀隆
- Organizer
  第39回　国際心臓研究学会日本部会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08155
[Presentation] Establishment of in vivo ATP Imaging System in Beating Heart and Development of Novel Drug Therapy to Increase Mitochondrial ATP production2021
- Author(s)
  木岡　秀隆
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08581
[Presentation] Visualization of ATP dynamics and protection against hypoxia in the heart2020
- Author(s)
  木岡　秀隆
- Organizer
  BCVR
- Data Source
  KAKENHI-PROJECT-19K08581
[Presentation] 11.7T-MRI装置を用いたマウス下肢骨格筋CrCESTイメージングの確立2019
- Author(s)
  高橋佑典, 齋藤茂芳, 木岡秀隆, 荒木力太, 高島成二, 坂田泰史, 吉岡芳親
- Organizer
  第47回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-19K08581
[Presentation] ”Analysis of genetic variants and chamber specific RNAexpressions in patients with advanced heart failure.”2018
- Author(s)
  木岡秀隆
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09501
[Presentation] Genetic Analysis and Chamber Specific Gene Expression Analysis in Patients with Cpc-PH and Ipc-PH2018
- Author(s)
  Hidetaka Kioka
- Organizer
  The 6th World Symposium on Pulmonary Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09501
[Presentation] Onco-Pulmo Cardiology “Molecular Targeted Drugs Associate Pulmonary Vascular and Cardiac Diseases”2018
- Author(s)
  木岡秀隆
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09501
[Presentation] Mitochondrial Energy Metabolism and Potential Metabolic Therapy for Heart Failure2016
- Author(s)
  木岡　秀隆
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K09501
[Presentation] In vivo Visualization of ATP Dynamics Under Hypoxia Reveals That G0/G1 Switch Gene 2 Provides Ischemic Tolerance Through the Increase of ATP Production
- Author(s)
  Hidetaka Kioka, Hisakazu Kato, Yoshihiro Asano, Yasushi Sakata, Masafumi Kitakaze, Seiji Takashima.
- Organizer
  American Heart Association Scientific Sessions 2014
- Place of Presentation
  Chicago, Illinois,USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26860559

1. 坂田泰史 (00397671)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. Ohtani Tomohito (30623897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Asano Yoshihiro (60527670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Minamiguchi Hitoshi (90648495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 塚本泰正 (80747072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 宮下洋平 (60816312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 塚本蔵 (80589151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 高島成二 (90379272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 加藤久和 (30589312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 肥後修一朗 (00604034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KANEKO Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TANIGUCHI Tatsunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. CHIMURA Misato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ASAKURA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. NAKANO Astushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. MIN Kyung-Duk

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. ITO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. SAITO Shigeyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 新谷泰範

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 中山博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 北風政史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 山崎悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 浅沼博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 小倉尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 瀧原圭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIOKA HIDETAKA 木岡 秀隆

Kioka Hidetaka 木岡 秀隆

Research Projects

Research Products

Co-Researchers

時空間代謝イメージングによる心筋リバースリモデリングの本質解明と治療開発Principal Investigator

Principal Investigator

Project Period (FY)

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Identification of therapeutic targets for heart failure and development of intervention methods related to the control mechanism of cardiac pump function

Principal Investigator

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Stratification of myocardial failure and development of genomic medicine

Principal Investigator

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Elucidation of a neddylation dependent stress response in cardiomyocytes and drug discoveryPrincipal Investigator

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Establishment of in vivo imaging and research for novel heart failure therapy targeting metabolismPrincipal Investigator

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Identification of Novel Molecular Targets and Drug Development by Genomic and Multilayer-Omics Analysis of Hereditary Cardiomyopathies

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Evaluation for genetic predisposition and clinical pathological stratification in cardiac sarcoidosis

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Elucidation of the molecular mechanism of cardiac energy metabolism for the development of novel therapy for heart failurePrincipal Investigator

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Analyzing qualitative abnormality of red blood cell for investigating pathophysiology of heart failure

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The role of mitochondrial protein MENT in myocardial ischemic preconditioningPrincipal Investigator

Principal Investigator

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[Journal Article] Creatine Chemical Exchange Saturation Transfer (Cr-CEST) Imaging Can Evaluate Cisplatin-induced Testicular Damage2023

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[Journal Article] Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity2023

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[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022

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KIOKA HIDETAKA 木岡秀隆

Kioka Hidetaka 木岡秀隆