Yamashiro Yoshito 山城義人

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YAMASHIRO Yoshito 山城義人

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Researcher Number	70751923
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 室長
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立循環器病研究センター, 研究所, 室長 2022: 筑波大学, 生命領域学際研究センター, 助教 2021: 筑波大学, 生存ダイナミクス研究センター, 准教授 2018 – 2020: 筑波大学, 生存ダイナミクス研究センター, 助教 2015 – 2016: 筑波大学, 生命領域学際研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Transformative Research Areas, Section (III) / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 49010:Pathological biochemistry-related / Cardiovascular medicine Except Principal Investigator Basic Section 90110:Biomedical engineering-related / Basic Section 55030:Cardiovascular surgery-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 細胞外マトリクス / メカニカルストレス / 内皮間葉転換 / 低酸素応答 / 血管リモデリング / 血管 / YAP / Thrombospondin-1 / メカノトランスダクション / 大動脈瘤 … More / 血管病態 / 内皮間葉転換（EndMT) / 血管狭窄 / 低酸素 / マルチモダルECM / ライブイメージング / ストレス応答 / ECMダイナミクス / バイオメカニクス / 弾性線維 / オルガノイド / 接着斑 / 筋萎縮性側索硬化症 / 血管オルガノイド / 血管生物 / メカノセンシング / PAR-1 / 細胞接着斑 / シグナル伝達 / 細胞外マトリックス / 血管平滑筋細胞 / TGF-β / 大動脈瘤破裂 / TGFβ … More Except Principal Investigator DNA / 細胞骨格 / 細胞核 / メカノバイオロジー / 細胞バイオメカニクス / バイオマーカー / 脊髄障害 / shaggy aorta / 広報 / 若手支援 / 研究資源共有化 / 技術支援 / 細胞外マトリックス / ＤＮＡ Less

細胞骨格と核の「繋がり」に基づく生体恒常性維持・破綻メカニズムの解明
- Principal Investigator
  
  長山和亮
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Ibaraki University
AIによるステントグラフト内挿術後の脊髄障害発生予測モデル構築とバイオマーカー探索
- Principal Investigator
  
  清家愛幹
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  National Cardiovascular Center Research Institute
領域研究「細胞外情報を統御するマルチモーダルECM」の統括と運営
- Principal Investigator
  
  藤原裕展
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
Molecular mechanisms of ECM-mediated vessel wall remodelingPrincipal Investigator
- Principal Investigator
  
  山城義人
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  National Cardiovascular Center Research Institute
Investigation on the homeostasis mechanism of cells based on the nucleus-cytoskeleton connections
- Principal Investigator
  
  Nagayama Kazuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Ibaraki University
Preparation of vascular organoids by applying functional-elastin materialsPrincipal Investigator
- Principal Investigator
  
  Yamashiro Yoshito
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Cardiovascular Center Research Institute
  University of Tsukuba
Mechanotransduction mechanisms in vascular wall homeostasis and pathogenesisPrincipal Investigator
- Principal Investigator
  
  山城義人
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Cardiovascular Center Research Institute
  University of Tsukuba
Abnormal mechanosensing underlie aortic aneurysm formationPrincipal Investigator
- Principal Investigator
  
  Yamashiro Yoshito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Tsukuba
TGFb signaling pathways involved in rupture of aortic aneurysmsPrincipal Investigator
- Principal Investigator
  
  YAMASHIRO Yoshito
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba

All 2024 2023 2022 2021 2020 2019 2018 2016 2015

All Journal Article Presentation Book

[Book] 血管組織・細胞のバイオロジー2024
- Author(s)
  山城義人
- Publisher
  バイオマテリアル学会誌
- Data Source
  KAKENHI-PLANNED-23H04929
[Book] 血管組織・細胞のバイオロジー2024
- Author(s)
  山城義人
- Publisher
  バイオマテリアル学会誌
- Data Source
  KAKENHI-PROJECT-23K21373
[Book] 血管・リンパ管の機能制御と疾患メカニズム「メカノバイオロジーと研究」2022
- Author(s)
  山城義人、柳沢裕美
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23K21373
[Book] 医学のあゆみ2019
- Author(s)
  山城義人、柳沢裕美
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-18K15057
[Journal Article] Protective Role of Endothelial Fibulin‐4 in Valvulo‐Arterial Integrity2023
- Author(s)
  Nguyen Tram Anh Vu、Lino Caroline Antunes、Hang Huynh Thuy、Alves Juliano Vilela、Thang Bui Quoc、Shin Seung Jae、Sugiyama Kaori、Matsunaga Hiroko、Takeyama Haruko、Yamashiro Yoshito、Yanagisawa Hiromi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 12 Issue: 1
- DOI
  10.1161/jaha.122.026942
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-23H00431
[Journal Article] C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response2022
- Author(s)
  Shiota Tomo、Nagata Riko、Kikuchi Sotaro、Nanaura Hitoki、Matsubayashi Masaya、Nakanishi Mari、Kobashigawa Shinko、Isozumi Noriyoshi、Kiriyama Takao、Nagayama Kazuaki、Sugie Kazuma、Yamashiro Yoshito、Mori Eiichiro
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 750829-750829
- DOI
  10.3389/fcell.2022.750829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K17043, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-21K15032, KAKENHI-PROJECT-22K07725, KAKENHI-PROJECT-21H03804, KAKENHI-PROJECT-19K08150, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21K19881
[Journal Article] Partial endothelial-to-mesenchymal transition mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022
- Author(s)
  Yamashiro Yoshito、Ramirez Karina、Nagayama Kazuaki、Hattori Naoko、Liu Yu-Yu、Matsunaga Shinji、Tomita Shuhei、Kubota Yoshiaki、Yanagisawa Hiromi
- Journal Title
  
  Cardiovascular Research
  
  Volume: 12 Issue: 7 Pages: 1606-1618
- DOI
  10.1093/cvr/cvac190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-23K06365, KAKENHI-PROJECT-22K19890, KAKENHI-PLANNED-23H04929, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21H03804, KAKENHI-PROJECT-23K27352
[Journal Article] Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms2021
- Author(s)
  Sugiyama Kaori、Marzi Julia、Alber Julia、Brauchle Eva M.、Ando Masahiro、Yamashiro Yoshito、Ramkhelawon Bhama、Schenke-Layland Katja、Yanagisawa Hiromi
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 2 Issue: 5 Pages: 100261-100261
- DOI
  10.1016/j.xcrm.2021.100261
- NAID
  120007180697
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-21K15366, KAKENHI-PROJECT-23K21373
[Journal Article] Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels2021
- Author(s)
  Kimura Kenichi、Ramirez Karina、Nguyen Tram Anh Vu、Yamashiro Yoshito、Sada Aiko、Yanagisawa Hiromi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-88126-6
- NAID
  120007180733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-23K21373
[Journal Article] Role of PAR1-Egr1 in the initiation of Thoracic Aortic Aneurysm in Fibulin-4 deficient mice.2020
- Author(s)
  Shin SJ, Hang HT, Thang BQ, Shimoda T, Sakamoto H, Osaka M, Hiramatsu Y, Yamashiro Y, Yanagisawa H
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol.
  
  Volume: 40(8) Issue: 8 Pages: 1905-1917
- DOI
  10.1161/atvbaha.120.314560
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
[Journal Article] The Molecular Mechanism of Mechanotransduction in Vascular Homeostasis and Disease2020
- Author(s)
  Yamashiro Y, Yanagisawa H
- Journal Title
  
  Clin. Sci.
  
  Volume: 134(17) Issue: 17 Pages: 2399-2418
- DOI
  10.1042/cs20190488
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
[Journal Article] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling2020
- Author(s)
  Yamashiro Yoshito、Thang Bui Quoc、Ramirez Karina、Shin Seung Jae、Kohata Tomohiro、Ohata Shigeaki、Nguyen Tram Anh Vu、Ohtsuki Sumio、Nagayama Kazuaki、Yanagisawa Hiromi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 18 Pages: 9896-9905
- DOI
  10.1073/pnas.1919702117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22944, KAKENHI-PROJECT-17H02077, KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
[Journal Article] Novel ELN mutation in a Japanese family with a severe form of supravalvular aortic stenosis2019
- Author(s)
  Sugiyama K, Horigome H, Lin L, Murakami T, Shiono J, Yamashiro Y, Matsuura H, Yoda H, Yanagisawa H
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 7 Issue: 11
- DOI
  10.1002/mgg3.986
- NAID
  120007133081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07813, KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-17H04289
[Journal Article] Role of thrombospondin-1 in mechanotransduction and development of thoracic aortic aneurysm in mouse and humans.2018
- Author(s)
  Yamashiro Y, Thang BQ, Shin SJ, Lino CA, Nakamura T, Kim J, Sugiyama K, Tokunaga C, Sakamoto H, Osaka M, Davis EC, Wagenseil JE, Hiramatsu Y and Yanagisawa H.
- Journal Title
  
  Circulation Research
  
  Volume: 123(6) Issue: 6 Pages: 660-672
- DOI
  10.1161/circresaha.118.313105
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-16H05145, KAKENHI-PROJECT-17H04289, KAKENHI-PROJECT-17K19534
[Journal Article] Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.2018
- Author(s)
  Tsunezumi J, Sugiura H, Oinam L, Ali A, Thang BQ, Sada A, Yamashiro Y, Kuro-O M and Yanagisawa H.
- Journal Title
  
  Matrix Biology
  
  Volume: 74 Pages: 5-20
- DOI
  10.1016/j.matbio.2018.04.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-17H04289
[Journal Article] MMP17/MT4-MMP and thoracic aortic aneurysms: OPNing new potential for effective treatment2015
- Author(s)
  C. L. Papke, Y. Yamashiro, and H. Yanagisawa
- Journal Title
  
  Circulation Research
  
  Volume: 117 Pages: 109-112
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20898
[Journal Article] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysms in mice2015
- Author(s)
  Y. Yamashiro, C. L. Papke, J. Kim, L.-J. Ringuette, Q.-J. Zhang, Z.-P. Liu, H. Mirzaei, J. E. Wagenseil, E. C. Davis, and H. Yanagisawa
- Journal Title
  
  Science Signaling
  
  Volume: 8(399) Issue: 399
- DOI
  10.1126/scisignal.aab3141
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20898
[Journal Article] Loss of fibulin-4 disrupts collagen synthesis and maturation: Implications for pathology resulting from EFEMP2 mutations2015
- Author(s)
  C. L. Papke, J. Tsunezumi, L.-J. Ringuette, H. Nagaoka, M. Terajima, Y. Yamashiro, G. Urquhart, M. Yamauchi, E. C. Davis, and H. Yanagisawa
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 15;24(20) Issue: 20 Pages: 5867-79
- DOI
  10.1093/hmg/ddv308
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Vessel Remodeling via Extracellular Matrix2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  TARA Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] プロテオームで解き明かす、細胞外マトリクスを介した血管リモデリング2023
- Author(s)
  山城義人
- Organizer
  JPrOS 2023（日本プロテオーム学会）
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] Vessel Remodeling via Extracellular Matrix2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  TARA Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] プロテオームで解き明かす、細胞外マトリクスを介した血管リモデリング2023
- Author(s)
  山城義人
- Organizer
  JPrOS 2023（日本プロテオーム学会）
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Matrix-mediated mechanotransduction underlies Vessel wall remodeling2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  FAOPS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 内皮間葉転換を制御する細胞外情報と転写制御ネットワーク2023
- Author(s)
  山城義人
- Organizer
  第96回日本生化学会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] Partial EndMT mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  第87回日本循環器学会
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT in neointima formation2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  第55回日本結合組織学会 KSMB-JSMBM Joint Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT in neointima formation2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  第55回日本結合組織学会 KSMB-JSMBM Joint Symposium
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 細胞外マトリクスを介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  第8回　血管生物若手の会
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクスを介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  第8回　血管生物若手の会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 血管壁の恒常性維持機構と細胞外マトリクスの役割2023
- Author(s)
  山城義人
- Organizer
  日本平滑筋学会・若手の会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクスを介した介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  CVEM2023
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 細胞外マトリクスを介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  第3回血管研究会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 血管の恒常性維持と病態形成におけるメカノトランスダクション機序2023
- Author(s)
  山城義人
- Organizer
  第64回日本脈管学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 内皮間葉転換を制御する細胞外情報と転写制御ネットワーク2023
- Author(s)
  山城義人
- Organizer
  第96回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 血管の恒常性維持と病態形成におけるメカノトランスダクション機序2023
- Author(s)
  山城義人
- Organizer
  第64回日本脈管学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04929
[Presentation] 細胞外マトリクスを介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  第3回血管研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Matrix-mediated mechanotransduction underlies Vessel wall remodeling2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  FAOPS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  GRC2023 Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクスを介した介した血管リモデリング機構2023
- Author(s)
  山城義人
- Organizer
  CVEM2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT underlies neointima formation2023
- Author(s)
  Yoshito Yamashiro
- Organizer
  NAVBO Online Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022
- Author(s)
  山城義人
- Organizer
  CVMW2022・血管生物医学会
- Data Source
  KAKENHI-PROJECT-21K19881
[Presentation] Partial EndMT mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022
- Author(s)
  Yoshito Yamashiro
- Organizer
  International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 部分的内皮間葉転換の役割と意義2022
- Author(s)
  山城義人
- Organizer
  第7回血管生物医学会
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクス (ECM) が駆動する血管リモデリング機構について2022
- Author(s)
  山城義人
- Organizer
  関西共創の場　第15回若手人材育成セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19881
[Presentation] What have we learned from basic research for aortic aneurysm so far? -大動脈瘤の基礎研究から見えてきたトランスレーショナル研究への道しるべ-2022
- Author(s)
  山城義人
- Organizer
  第26回日本心血管内分泌代謝学会・中尾一和賞
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022
- Author(s)
  山城義人
- Organizer
  第30回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクスを介した血管リモデリング2022
- Author(s)
  山城義人
- Organizer
  国立循環器病研究センター　ZF Meeting
- Data Source
  KAKENHI-PROJECT-21K19881
[Presentation] 細胞外マトリクス（ECM）を介したメカノトランスダクション制御2022
- Author(s)
  山城義人
- Organizer
  第1回和歌山MatriCell研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Vessel wall remodeling and partial EndMT underlies neointima formation2022
- Author(s)
  Yoshito Yamashiro
- Organizer
  Cardiovascular Metobolic week 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Role of Partial EndMT in carotid artery ligation2022
- Author(s)
  山城義人
- Organizer
  第44回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Matrix-mediated Mechanotransduction2021
- Author(s)
  山城義人
- Organizer
  第60回日本生体医工学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 細胞外マトリクスを介したメカノトランスダクション2021
- Author(s)
  山城義人
- Organizer
  マトリセルフォーラム
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] 血管病態の発症に寄与する細胞外マトリクスを介したメカノトランスダクション2021
- Author(s)
  山城義人
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT contributes to vessel wall remodeling after carotid artery ligation2021
- Author(s)
  山城義人
- Organizer
  CVMW2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Partial EndMT and its function on Cardiovascular Disease2021
- Author(s)
  山城義人
- Organizer
  第94回日本生化学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21373
[Presentation] Thrombospondin-1を介した大動脈瘤血管壁の機械刺激応答と大動脈瘤形成における役割2020
- Author(s)
  山城義人
- Organizer
  第52回日本結合組織学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] 血管のメカニカルストレス応答と恒常性維持のメカニズム2020
- Author(s)
  山城義人
- Organizer
  千葉大学医学研究院　内分泌代謝・血液・老年内科学講座セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP signaling pathway in the remodeling of blood vessel.2020
- Author(s)
  Yoshito Yamashiro
- Organizer
  The 84th Annual Scientific Meeting of Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] 血管のメカニカルストレス応答機構の解明と病態発症のメカニズム2020
- Author(s)
  山城義人
- Organizer
  順天堂大学DBSB Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] 血管の恒常性維持を担うECM-Cell相互作用2020
- Author(s)
  山城義人
- Organizer
  KOWA Web Conference
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] 血管リモデリングを制御する細胞外マトリクスを介したメカノトランスダクション2020
- Author(s)
  山城義人
- Organizer
  第93回日本生化学学会年会
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP signaling pathway in the remodeling of vessel wall2019
- Author(s)
  Yoshito Yamashiro
- Organizer
  NAVBO: Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP signaling pathway in the remodeling of vessel wall2019
- Author(s)
  Yoshito Yamashiro
- Organizer
  The 3nd JCS Council Forum on Basic CardioVascular Research
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] メカノジャックで紐解く、血管のリモデリング2019
- Author(s)
  山城義人
- Organizer
  第42回　日本分子生物学会年会　ワークショップ「生物情報はいかにして細胞の未来を紡ぐのか？」
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] マトリクスメカノトランスダクションと血管リモデリング2019
- Author(s)
  山城義人
- Organizer
  CardioVascular and Metabolic Week 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm2018
- Author(s)
  Yoshito Yamashiro
- Organizer
  Korea-Japn joint symposium for vascular biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm2018
- Author(s)
  Yoshito Yamashiro
- Organizer
  日本血管生物医学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm2018
- Author(s)
  Yoshito Yamashiro
- Organizer
  GenTAC Aortic Sumit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Thrombospondin-1を介した大動脈瘤血管壁の機械刺激応答2018
- Author(s)
  山城義人
- Organizer
  日本結合組織学会
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Role of thrombospondin-1 in mechanotransduction and development of thoracic aortic aneurysm2018
- Author(s)
  Yoshito Yamashiro
- Organizer
  Phosphatase Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15057
[Presentation] Vessel wall integrity under the mechanical stress2016
- Author(s)
  Yoshito Yamashiro
- Organizer
  日本血管生物医学会若手の会
- Place of Presentation
  東北大学　加齢医学研究所（仙台）
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal Mechanosensing underling ascending aneurysm formation2016
- Author(s)
  Yoshito Yamashiro
- Organizer
  第48回日本結合組織学会
- Place of Presentation
  長崎大学医学部（長崎県・長崎市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing underling aortic aneurysm formation2016
- Author(s)
  Yoshito Yamashiro
- Organizer
  Molecular Cardiovascular Conference II
- Place of Presentation
  東京ドームホテル（東京都・文京区）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing and activation of slingshot-cofilin pathway underlie initiation and expansion of ascending aortic aneurysms in fibulin-4 deficient mice2015
- Author(s)
  Yoshito Yamashiro
- Organizer
  日本細胞生物学会
- Place of Presentation
  タワーホール船堀（東京）
- Year and Date
  2015-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysm in mice2015
- Author(s)
  Yoshito Yamashiro
- Organizer
  大動脈病態研究会
- Place of Presentation
  久留米大学（福岡）
- Year and Date
  2015-08-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysm in mice2015
- Author(s)
  Yoshito Yamashiro
- Organizer
  日本血管生物医学会
- Place of Presentation
  神戸国際会議場（兵庫）
- Year and Date
  2015-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysm in mice2015
- Author(s)
  Yoshito Yamashiro
- Organizer
  Gordon Research Conference
- Place of Presentation
  ニューイングランド大学（メイン州、U.S.A)
- Year and Date
  2015-07-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20898
[Presentation] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysm in mice2015
- Author(s)
  Yoshito Yamashiro
- Organizer
  エラスチン研究会
- Place of Presentation
  私学会館アルカディア市ヶ谷（東京）
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-15K20898

1. Nagayama Kazuaki (10359763)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 上杉薫 (20737027)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 出口真次 (30379713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Yanagisawa Hiromi (40746301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 藤原裕展 (20615744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 木戸屋浩康 (00543886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 島村徹平 (00623943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高橋淑子 (10183857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鳴瀧彩絵 (10508203)

# of Collaborated Projects: 1 results

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10. 秋元文 (10585805)

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11. 長山雅晴 (20314289)

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12. 永樂元次 (40415097)

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13. 関口清俊 (50187845)

# of Collaborated Projects: 1 results

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14. 松田知己 (50419206)

# of Collaborated Projects: 1 results

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15. 高田慎治 (60206753)

# of Collaborated Projects: 1 results

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16. 岸田晶夫 (60224929)

# of Collaborated Projects: 1 results

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17. 大槻純男 (60323036)

# of Collaborated Projects: 1 results

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18. 三輪佳宏 (70263845)

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19. 三井優輔 (70634129)

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20. 秋吉一成 (90201285)

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21. 板倉英祐 (90754218)

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22. 森英一朗 (70803659)

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23. 吉野大輔 (80624816)

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24. 清家愛幹 (20728381)

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25. 松田均 (20294217)

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26. 畠山金太 (60325735)

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27. 中岡良和 (90393214)

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28. 小林三紀 (90898727)

# of Collaborated Projects: 1 results

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29. 久保田義顕 (50348687)

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30. 山本希美子 (00323618)

# of Collaborated Projects: 1 results

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31. 杉江和馬

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32. 七浦仁紀

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# of Collaborated Products: 1 results
33. 桐山敬生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 塩田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 安藤正浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 堀米仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashiro Yoshito 山城 義人

YAMASHIRO Yoshito 山城 義人

Research Projects

Research Products

Co-Researchers

細胞骨格と核の「繋がり」に基づく生体恒常性維持・破綻メカニズムの解明

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AIによるステントグラフト内挿術後の脊髄障害発生予測モデル構築とバイオマーカー探索

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領域研究「細胞外情報を統御するマルチモーダルECM」の統括と運営

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Molecular mechanisms of ECM-mediated vessel wall remodelingPrincipal Investigator

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Investigation on the homeostasis mechanism of cells based on the nucleus-cytoskeleton connections

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Preparation of vascular organoids by applying functional-elastin materialsPrincipal Investigator

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Mechanotransduction mechanisms in vascular wall homeostasis and pathogenesisPrincipal Investigator

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Abnormal mechanosensing underlie aortic aneurysm formationPrincipal Investigator

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TGFb signaling pathways involved in rupture of aortic aneurysmsPrincipal Investigator

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[Book] 血管組織・細胞のバイオロジー2024

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[Book] 血管組織・細胞のバイオロジー2024

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[Book] 血管・リンパ管の機能制御と疾患メカニズム「メカノバイオロジーと研究」2022

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[Book] 医学のあゆみ2019

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[Journal Article] Protective Role of Endothelial Fibulin‐4 in Valvulo‐Arterial Integrity2023

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DOI

Yamashiro Yoshito 山城義人

YAMASHIRO Yoshito 山城義人