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KOBAYASHI Koichi  小林 紘一

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… Alternative Names

KOBAYASHI Kouichi  小林 紘一

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Researcher Number 80051704
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012: 慶應義塾大学, 医学部, 名誉教授
2010: 慶應義塾大学, 医学部, 名誉教授
2009: 慶應義塾大学, 医学部
2007 – 2008: 慶應義塾大学, 医学部, 名誉教授
1998 – 2007: 慶應義塾大学, 医学部, 教授 … More
2004 – 2006: 慶應義塾大学, 医学部(外科), 教授
2003: Keio University, School of Medicine, Professor
2001: 慶応義塾大学, 医学部, 教授
1998: 慶応大学, 医学部, 教授
1996: 慶應義塾大学, 医学部・外科, 教授
1995 – 1996: 慶応義塾大学, 医学部, 教授
1992 – 1996: 慶應義塾大学, 医学部, 教授
1995: 慶應義塾大学, 理工学部, 教授
1989 – 1991: 慶應義塾大学, 医学部, 講師
1989 – 1990: 慶應義塾大学, 医学部・外科, 講師
1988: 慶応義塾大学, 医学部外科, 講師 Less
Review Section/Research Field
Principal Investigator
General surgery / Thoracic surgery / Thoracic surgery
Except Principal Investigator
Thoracic surgery / Thoracic surgery / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / General surgery / Fluid engineering / Applied optics/Quantum optical engineering
Keywords
Principal Investigator
人工酸素運搬体 / 人工赤血球 / artificial oxygen carrier / LY-80 / ラット / chemotherapy / 放射線療法 / 腫瘍の酸素化 / tumor irradiation / tumor perfusion … More / tumor oxygenation / 腎腫瘍 / 酸素代謝 / 放射線照射 / 腫瘍潅流 / 腫瘍酸素化 / radiation / Ly-80 / tumor / rat / 補助科学療法 / 動脈内注入 / 腫瘍循環 / 腫瘍内酸素分圧 / LK-80 / 抗癌剤 / 腫瘍 / increment of sensitivity / drug sensitivity test / oxygenations of tumors / 腫瘍細胞の酸素化 / 化学療法 / 感受性の増強 / 抗癌剤感受性試験 / exchange transfusion / lipid heme microsphere / red blood cell substitute / totally synthetic oxygen carrier / 脱血交換実験 / lipid-heme-microsphere(LHM) / リピドヘムマイクロスフェア / 全合成系酸素運搬体 / 酸素運搬 / リポソームヘム / リポソ-ムヘム / 完全合成系酸素運搬体 / リピドヘム-マイクロスフェア / 全合成系人工酸素運搬体 / 酸素運搬能 / ヘモグロビンカプセル化 / ヘモグロビンカプセル化人工赤血球 … More
Except Principal Investigator
肺癌 / 人工酸素運搬体 / 人工赤血球 / CYFRA / 腫瘍マーカー / マイクロサンプリング法 / 気管支鏡 / 腫瘍循環 / CEA / 微小循環 / ヘモグロビン / 人工血液 / 低酸素 / リポソ-ムヘム / PTEN / VEGF / HIF-1α / Bronchoscopy / angiogenesis / 血管新生 / Microcirculation / ヘモグロビン小胞体 / ヘモレオロジー / 酸素輸液 / 輸血代替 / リポソーム / マイクロサンプリング / プロテオーム解析 / 気道上皮被覆液 / 一酸化窒素 / 人工臓器工学 / 放射線治療 / 癌 / Tumor markers / Proteomics / Lung cancer / Epithelial lining fluid / Microsampling / 気道被覆液 / プロテオミクス / oxymetry / hypoxia / tumor microcirculation / cancer / 腫瘍内酸素分圧 / 腹水肝癌 / 組織酸素分圧 / 組織酸素分圧測定 / hypoxic condition / non small cell lung cancer / 腫瘍内低酸素 / 原発性非小細胞肺癌 / 原発性肺癌 / Liposome / Artificial Blood / Hemorheology / Oxygen release / Ischemia / Hemoglobin / Artificial Red Cells / レオロジー制御 / 酸素放出 / 虚血 / 微小循環動態 / Tumor marker / Lung Cancer / Microsampling method / Interstitial matrix / Heparan sulphate proteoglycan / lung metastasis / heparanase / ヘパリナーゼ / 腫瘍内血管密度 / ヘパラナーゼ / ヘパラン硫酸プロテオグリカン / 間質組織 / プロテオグリカン / 肺転移 / Heparanase活性 / tumor marker / microsampling method / bronchoscopy / lung cancer / シフラ / 腫瘍コーカー / laser confocal microscope / nitric oxide / Hemogobin-Vesicle / artificialoxygen carrier / pulmonary microcirculation / lung neoplasm / metastasis / 肺微少循環 / 肺微小循環 / 共焦点レーザー顕微鏡 / 肺循環 / 転移性肺腫瘍 / Methemoglobin / Diagnostics / Non-invasive Method / Metabolism / Con focal Laser Scanning Microscopy / Hemoglobin-Vesicles / Artificial Oxygen Carrier / 過渡吸収スペクトル / 細網内皮系 / 出血ショック / 医用・生体画像 / 生体情報・計測 / 生体機能材料 / メトヘモグロビン / 診断法 / 非侵襲観測法 / 代謝過程 / レーザー共焦点顕微鏡 / convetive resonance / seondary flow / biomechanics / high frequency oscillation / biofluid mechanics / oscillatory flow / respiration mechanics / 気道 / 軸方向輸送 / 分岐管 / バイオメカニクス / 対流レゾナンス / 二次流れ / バイオメカニズム / 高頻度換気人工呼吸 / 生物流体力学 / 振動流 / 呼吸力学 / Cancer Diagnosis / Cancer therapy / Luminol reaction / Oxygene radical / Photosensitive material / Dye laser / Photodynamic treatment / Polymer optical fiber / 癌診断 / 癌治療 / ルミノール反応 / 活性酸素 / 色素レーザ / 光感受性物質 / 光化学療法 / ポリマー光ファイバ / liver perfusion test / oxygen dynamics / oxygen transport / animal test / microcirculation / hemoglobin vesicle / hemoglobin / red cell substitute / リン脂質小胞体 / 肝灌流試験 / 血流動態 / 肝潅流試験 / 酸素動力学 / 酸素運搬 / 動物試験 / 赤血球代替物 / 分子集合体 / 再生医療 / 臓器灌流 / 血液代替物 / 再生医工学 / プロテオーム / 非結核性抗酸菌症 / 呼吸器外科 / 癒着防止 / 吸水性ゲル / ポリグルタミン酸架橋 / ポリグルタミン酸架橋体 / 吸水性ハイドロゲル / 癒着 / レオロジー / 一酸化炭素 / 生体機能利用 / ナノバイオ / 生物・生体工学 / 生体材料 / 転移 / がん / 呼吸器外科学 / ストローマ細胞 / がん転移 / 放射線治寮 / 酸素消費率 / 手術成績 / 外科治療 / 自己血輸血 / 輸血 / 全合成系人工赤血球 / 全合成系酸素運搬体 Less
  • Research Projects

    (30 results)
  • Research Products

    (123 results)
  • Co-Researchers

    (43 People)
  •  Bioengineering of artificial red cells for clinical application

    • Principal Investigator
      SAKAI Hiromi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Waseda University
  •  Biochemical and proteomic analysis of epithelial lining fluid for early diagnosis of respiratory diseases

    • Principal Investigator
      WATANABE Masazumi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Artificial Red Cells : Physiological Importance of the Ligand Reaction Dynamism and the New Application for Ligand Therapy

    • Principal Investigator
      SAKAI Hiromi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Waseda University
  •  Application of hydrogels for adhesion prevention after thoracotomy

    • Principal Investigator
      IZUMI Yotaro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Enhanced radiation response andn inhibition of angiogenesis by artificial oxygen carrier

    • Principal Investigator
      HORINOUCHI Hirohisa
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Lung cancer cells metastasize together with tumor-derived host cells

    • Principal Investigator
      KOHNO Mitsutomo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  "Analysis of oxygen releasing behavior of hemoglobin-vesicles (nano-particles) and the mechanism of oxygenation of ischemic tissue."

    • Principal Investigator
      SAKAI Hiromi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Waseda University
  •  Hypoxic condition of the tumor and malignant progression in non-small cell lung cancer

    • Principal Investigator
      EGUCHI Keisuke
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Control of angiogenesis by attenuation of oxygen tension in the metastatic tumor of the lung

    • Principal Investigator
      HORINOUCHI Hirohisa
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Analysis of epithelial lining fluid covered by bronchoscopic microsampling method for diagnosis of small size lung adenocarcinoma

    • Principal Investigator
      WATANABE Masazumi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Changes in oxygen metabolism in solid tumors by administration of artificial oxygen carriersPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Koichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Analysis of metastasis mechanism in experimental lung metastasis with heparanase transgenic tumor cells

    • Principal Investigator
      HORINOUCHI Hirohisa
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Early diagnosis of small sized lung adenocarcinoma using bronchoscopic microsampling method

    • Principal Investigator
      WATANABE Masazumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Tumor sensitization to chemotherapy of radiation by artificial oxygen carriersPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Koichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KEIO UNIVERSITY
  •  Microhemodynamics after Infusion of an Artificial O_2 Carriers Using Laser Flash Irradiation.

    • Principal Investigator
      SAKAI Hiromi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Waseda University
  •  Analysis of microcirculation of experimental metastatic lung tumor using artificial oxygen carrier as a tool for altering the microvascular tone

    • Principal Investigator
      HORINOUCHI Hirohisa
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Bronchoscopic microsampling method for the diagnosis of small lung cancer

    • Principal Investigator
      WATANABE Masazumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Enhancement of gas transfer due to the convective resonance in the bifurcating tube of the airway

    • Principal Investigator
      TANISHITA Kazuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Fluid engineering
    • Research Institution
      Keio University
  •  Tumor oxygenation to in crease sensitivity to anti-cancerous drug by using artificial oxygen carrierPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Koichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      Keio University
  •  自己血輸血の免疫増強作用が肺癌手術の予後に及ぼす影響に関する研究

    • Principal Investigator
      菊地 功次
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  Preclinical Evaluation Tests of Red Cell Substitutes by Microcirculatory Dynamical Analyzes

    • Principal Investigator
      TSUCHIDA Eishun
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Waseda University
  •  Effect on Biological Tissues in Photodynamic Diagnosis and Therapy using Plastic Optical Fiber Amplifier

    • Principal Investigator
      SASAKI Keisuke
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied optics/Quantum optical engineering
    • Research Institution
      Keio University
  •  Oxygen Carrying Capacity of Totally Synthetic Oxygen Carrier-Lipidheme-Microsphere-Principal Investigator

    • Principal Investigator
      KOBAYASHI Koichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Keio University
  •  全合成系人工酸素運搬体リピドヘムマイクロスフェアの酸素運搬能に関する基礎的研究Principal Investigator

    • Principal Investigator
      小林 紘一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  ヘモクロビンカプセル化人工赤血球の安全性と酸素運搬能に関する基礎的研究Principal Investigator

    • Principal Investigator
      小林 紘一
    • Project Period (FY)
      1992
    • Research Institution
      Keio University
  •  人工赤血球(リポソ-ムヘム)の臨床応用に関する研究

    • Principal Investigator
      石原 恒夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  ヘモグロビンカプセル化人工赤血球の安全性と酸素運搬能に関する基礎的研究Principal Investigator

    • Principal Investigator
      小林 紘一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Keio University
  •  人工赤血球(リポソ-ムヘム)の臨床応用に関する研究

    • Principal Investigator
      石原 恒夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Keio University
  •  人工赤血球の臨床応用に関する研究

    • Principal Investigator
      石原 恒夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Keio University
  •  人工赤血球(リポソ-ムヘム)の臨床応用に関する基礎的研究Principal Investigator

    • Principal Investigator
      小林 紘一
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Keio University

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier. In : Chemistry and Biochemistry of Oxygen Therapeutics : from Transfusion to Artificial Blood. (Ed. by S. Bettati and A. Mozzarelli), Chapter 272011

    • Author(s)
      H. Sakai, H. Horinouchi, E. Tsuchida, K. Kobayashi
    • Publisher
      John Wiley & Sons
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Book] Hb-vesicles as a cellular type Hb-based O2 carrier. In : Chemistry and Biochemistry of Oxygen The rapeutics(Bettati & Mozzarelli, Ed.)2011

    • Author(s)
      H.Sakai, H.Horinouchi, E.Tsuchida, K.Kobayashi
    • Total Pages
      442
    • Publisher
      John Wiley & Sons
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Book] Oxygen Transport to Tissue XXXI(Hemoglobin-vesicle, a cellular artificial oxygen carrier, that fulfils the physiological roles of the red blood cells structure).2010

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida
    • Publisher
      Adv. Exp. Med. Biol.
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Book] 人工酸素運搬体.「からだと酸素の事典」酸素ダイナミクス研究会編.第5章:酸素の利用.pp.478-4842009

    • Author(s)
      堀之内宏久, 小林紘一, 酒井宏水, 土田英俊
    • Total Pages
      583
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Book] MOOK肺癌の臨床疫学・病理・発見・診断・治療2006-2006/高齢者肺癌の外科治療2006

    • Author(s)
      堀之内宏久, 小林紘一
    • Total Pages
      471
    • Publisher
      篠原出版新社
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Book] "Blood Substitutes" Chapt. 44 "Hemoglobin-Vesicles as a Molecular Assembly : Characteristics of Preparation Process and Performances as Artificial Oxygen Carriers." (Ed. By Robert M. Winslow)2006

    • Author(s)
      H.Sakai, K.Sou, S.Takeoka, K.Kobayashi, E.Tsuchida
    • Publisher
      Elsevier
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] Blood Substitutes (Ed.By Robert M.Winslow), Chapt.44, pp.514-5222006

    • Author(s)
      Sakai H, Sou K, Takeoka S, Kobayashi K, Tsuchida E
    • Total Pages
      9
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] "Hb-vesicles as Artificial O2 Carriers". In : Artificial O2 Carrier : Its Front Line, Keio Univ.Intern.Symp.for Life Sci.& Med.Vol.12(Eds.by K.Kobayashi, E.Tsuchida, and H.Horinouchi.)2005

    • Author(s)
      Sakai H, Sou K, Takeoka S, Kobayashi K, Tsuchida E.
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] 先端医療シリーズ37「人工臓器・再生医療の最先端」第16章-4.pp.279-2862005

    • Author(s)
      土田英俊, 酒井宏水, 小松晃之, 小林紘一
    • Total Pages
      8
    • Publisher
      寺田国際事務所/先端医療技術研究所
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] 先端医療シリーズ37「人工臓器・再生医療の最先端」第16章-4.酸素輸液(人工赤血球)の臨床応用2005

    • Author(s)
      土田英俊, 酒井宏水, 小松晃之, 小林紘一
    • Publisher
      寺田国際事務所/先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] Artificial Oxygen Carrier : Its Front Line, Keio University International Symposia for Life Sciences and Medicine Vol.12 (Eds. by K. Kobayashi, E. Tsuchida, and H. Horinouchi) ("Hemoglobin-vesicles (HbV) as Artificial Oxygen Carriers")2005

    • Author(s)
      H.Sakai, K.Sou, S.Takeoka, K.Kobayashi, E.Tsuchida
    • Publisher
      Springer-Verlag (2005).
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] "Safety and Efficacy of Hb-Vesicles and Albumin-Hemes". In : Artificial O2 Carrier : Its Front Line, Keio Univ.Intern.Symp.for Life Sci.& Med.Vol.12(Eds.by K.Kobayashi, E.Tsuchida, and H.Horinouchi.)2005

    • Author(s)
      Kobayashi, Horinouchi, Sakai, komatsu, Takeoka, Tsuchida, et al.
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Book] 「医療用マテリアルと機能膜」第5章、人工赤血球2005

    • Author(s)
      酒井宏水, 宗慶太郎, 武岡真司, 小林紘一, 土田英俊
    • Publisher
      (株)シーエムシー出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Fluid resuscitation of hemorrhagic shock with Hemoglobin vesicles in Beagle dogs : pilot study2012

    • Author(s)
      M.Yamamoto, H.Horinouchi, Y.Seishi, K.Kobayashi, H.Sakai, et al
    • Journal Title

      Artif.Cells Blood Substitutes Biotechnol

      Volume: 40 Issue: 1-2 Pages: 179-195

    • DOI

      10.3109/10731199.2011.637929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Effect of the cellular-type artificial oxygen carrier Hb-vesicle as a resuscitative fluid for pre-hospital treatment : Experiments in a rat uncontrolled hemorrhagic shock model.2012

    • Author(s)
      Y. Seishi, H. Horinouchi, H. Sakai, K. Kobayashi
    • Journal Title

      Shock

      Volume: 38 Pages: 153-158

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Removal of Hemoglobin-vesicles from circulating blood by using centrifugation and ultrafiltration.2012

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, E. Tsuchida, K. Kobayashi.
    • Journal Title

      Artif. Organs

      Volume: 36 Pages: 202-209

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Fluid resuscitation of hemorrhagic shock with Hemoglobin vesicles in Beagle dogs : pilot study.2012

    • Author(s)
      M. Yamamoto, H. Horinouchi, Y. Seishi, N. Sato, M. Itoh, K. Kobayashi, H. Sakai
    • Journal Title

      Artif. Cells Blood Substitutes Biotechnol

      Volume: 40 Pages: 179-195

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Hemoglobin vesicle as an effective blood substitute and its removal from circulating blood2012

    • Author(s)
      H.Sakai, K.Sou, H.Horinouchi, E.Tsuchida, K.Kobayashi
    • Journal Title

      Artificial Organs

      Volume: 36 Issue: 2 Pages: 202-209

    • DOI

      10.1111/j.1525-1594.2011.01236.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Fourteen-days observation and pharmacokinetic evaluation after massive intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers) in cynomolgus monkeys.2012

    • Author(s)
      K. Taguchi, H. Watanabe, H. Sakai, H. Horinouchi, K. Kobayashi, T. Maruyama, M. Otagiri
    • Journal Title

      J. Drug Metab. Toxicol

      Volume: 3 Pages: 1000128-1000128

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2011

    • Author(s)
      K. Taguchi, M. Miyasato, H. Watanabe, H. Sakai, H. Horinouchi, K. Kobayashi, E. Tsuchida, T. Maruyama, M. Otagiri
    • Journal Title

      J. Pharmaceut. Sci.

      Volume: 100 Pages: 775-783

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Repeated injection of high dose of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011

    • Author(s)
      K. Taguchi, Y. Iwao, H. Watanabe, D. Kadowaki, H. Sakai, K. Kobayashi, H. Horinouchi, T. Maruyama, M. Otagiri
    • Journal Title

      Drug Metab. Dispos

      Volume: 39 Pages: 484-489

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Fluid resuscitation with hemoglobin vesicles prevents Esherichia coli growth via complement activation in a hemorrhagic shock rat model.2011

    • Author(s)
      K. Taguchi, S. Ogaki, H. Watanabe, D. Kadowaki, H. Sakai, K. Kobayashi, H. Horinouchi, T. Maruyama, M. Otagiri
    • Journal Title

      J. Pharmacol. Exp. Therap

      Volume: 337 Pages: 201-208

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Intravenous injection of Hb-vesicles (artificial oxygen carriers) after hemodilution with a series of plasma expanders (water-soluble biopolymers) in a rat repeated hemorrhage model.2011

    • Author(s)
      H. Sakai, N. Miyagawa, H. Horinouchi, S. Takeoka, M. Takaori, E. Tsuchida, K. Kobayashi
    • Journal Title

      Polymers Adv. Technol.

      Volume: 22 Pages: 1216-1222

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1.2011

    • Author(s)
      Takada Y, Gresh L, Bozec A, Ikeda E, Kamiya K, Watanabe M, Kobayashi K, Asano K, Toyama Y, Wagner EF, Matsuo K.
    • Journal Title

      Oncogene (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591677
  • [Journal Article] Phagocytosis of liposome particles by rat splenic immature monocytes makes them transiently and highly immunosuppressive in ex vivo culture condition.2011

    • Author(s)
      D. Takahashi, H. Azuma, H. Sakai, K. Sou, D. Wakita, H. Abe, M. Fujihara, H. Horinouchi, K. Kobayashi, T. Nishimura, H. Ikeda.
    • Journal Title

      J. Pharmacol. Exp. Therap

      Volume: 337 Pages: 42-49

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Gas bioengineering using hemoglobin-vesicles for versatile clinical application2011

    • Author(s)
      H. Sakai, S. Takeoka, K. Kobayashi
    • Journal Title

      Curr. Pharmaceut. Design

      Volume: 17 Pages: 2352-2359

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Hemoglobin-vesicle, a cellular artificial oxygen carrier, that fulfils the physiological roles of the red blood cells structure2010

    • Author(s)
      H.Sakai, K.Sou, H.Horinouchi, K.Kobayashi, E.Tsuchida
    • Journal Title

      Adv.Exp.Med.Biol. 662

      Pages: 433-438

    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Cytokine profiles of bronchoalveolar lavage fluid in patients with pneumocystis pneumonia.2010

    • Author(s)
      Tasaka S, Kobayashi S, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Mizokuchi K, Ishii M, Takeuci T, Hasegawa N.
    • Journal Title

      Microbiol Immunol 54

      Pages: 425-433

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591677
  • [Journal Article] Hemoglobin-vesicle, a cellular artificial oxygen carrier, that fulfils the physiological roles of the red blood cells structure.2010

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida
    • Journal Title

      Adv. Exp. Med. Biol.

      Volume: 662 Pages: 433-438

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Hepatically-metabolized and .excreted artificial oxygen carrier, hemoglobin-vesicles, can be safely used under conditions of hepatic impairment.2010

    • Author(s)
      K. Taguchi, M. Miyasato, H. Ujihara, H. Watanabe, D. Kadowaki, H. Sakai, E. Tsuchida, H. Horinouchi, K. Kobayashi, T. Maruyama, M. Otagiri
    • Journal Title

      Toxicol. Appl. Pharmacol.

      Volume: 248 Pages: 234-241

    • Data Source
      KAKENHI-PROJECT-22300161
  • [Journal Article] Hemoglobin-vesicles and red blood cells as carriers of carbon monoxide prior to oxygen for resuscitation after hemorrhagic shock in a rat model2009

    • Author(s)
      H. Sakai, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Journal Title

      Shock 31

      Pages: 507-514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Review of hemoglobinvesicles as artificial oxygen carriers2009

    • Author(s)
      Sakai H, Sou K, Horinouchi H, Kobayashi K, Tsuchida E.
    • Journal Title

      Artif Organs 33

      Pages: 139-145

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Hemoglobin vesicles and red blood cells as carriers of carbon monoxide prior to oxygen for resuscitation after hemorrhagic shock in a rat model2009

    • Author(s)
      Sakai H, Horinouchi H , Tsuchida E, Kobayashi K.
    • Journal Title

      Shock 31

      Pages: 507-514

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Histopathological changes of rat brain after direct injection of hemoglobin-vesicles (oxygen carriers) and neurological impact in an intracerebral hemorrhage model2009

    • Author(s)
      H. Sakai, M. Okamoto, E. Ikeda, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Journal Title

      J. Biomed. Mater. Res. 90A

      Pages: 1107-1119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Fluid resuscitation with artificial oxygen carriers in hemorrhaged rats: Profiles of Hb-vesicles degradation and hematopoiesis for 14 days2009

    • Author(s)
      H. Sakai, Y. Seishi, Y. Obata, S. Takeoka, H. Horinouchi, E. Tsuchida, K. Kobayashi.
    • Journal Title

      Shock 31

      Pages: 192-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry2009

    • Author(s)
      E.Tsuchida, K.Sou, A.Nakagawa, H.Sakai, T.Komatsu, K.Kobayashi.
    • Journal Title

      Bioconjugate Chem. 20

      Pages: 1419-1440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifies tumor response to irradiation.2009

    • Author(s)
      Yamamoto M, Izumi Y, Horinouchi H, Teramura Y, Sakai H, Kohno M, Watanabe M, Kawamura M, Adachi T, Ikeda E, Takeoka S, Tsuchida E, Kobayashi K.
    • Journal Title

      J Surg Res. (Epub 2008 Jan 17) 151(1)

      Pages: 48-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591410
  • [Journal Article] ヘモグロビン小胞体を含有する血液検体の臨床検査2009

    • Author(s)
      宗慶太郎, 小峰梨沙, 酒井宏水, 小林紘一, 土田英俊, 村田満
    • Journal Title

      人工血液 17

      Pages: 6-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Hemoglobin-vesicles and red blood cells as carriers of carbon monoxide prior to oxygen for resuscitation after hemorrhagic shock in a rat model2009

    • Author(s)
      H.Sakai, H.Horinouchi, K.Kobayashi, E.Tsuchida
    • Journal Title

      Shock 31

      Pages: 507-514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifies tumor response to irradiation2009

    • Author(s)
      Yamamoto M, Izumi Y, Horinouchi H, Teramura Y, Sakai H, Kohno M, Watanabe M, Kawamura M, Adachi T, Ikeda E, Takeoka S, Tsuchida E, Kobayashi K
    • Journal Title

      J Surg Res 151

      Pages: 48-54

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591410
  • [Journal Article] Review of hemoglobin-vesioles as artificial oxygen carriers2009

    • Author(s)
      H. Sakai, K. Sou, H. Horinouohi, K. Kobayashi, E. Tsuchida
    • Journal Title

      Artif. Organs 33

      Pages: 139-145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Histopathological changes of rat brain after direct injection of Hb-vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model2008

    • Author(s)
      Sakai H, Okamoto M, Ikeda E, Horinouchi H, Kobayashi K, Tsuchida E.
    • Journal Title

      J Biomed Mater Res A.(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Histopathological features and prognostic significance of the micropapillary pattern in lung adenocarcinoma2008

    • Author(s)
      Kamiya K, Hayashi Y, Douguchi J, Hashiguchi A, Yamada T, Izumi Y, Watanabe M, Kawamura M, Horinouchi H, Shimada N, Kobayashi K, Sakamoto M.
    • Journal Title

      Mod Pathol.(Epub 2008 May 30) 21(8)

      Pages: 992-1001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Histopathological changes of rat brain after direct injection of Hb-vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model2008

    • Author(s)
      Sakai H, Okamoto M, Ikeda E, Horinouchi H, Kobayashi K, Tsuchida E.
    • Journal Title

      J Biomed Mater Res A.(Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Structure, photophysical property, and cytotoxicity of human serum albumin complexed with tris(dicarboxymethylene)[60]fullerene2008

    • Author(s)
      Qu X, Komatsu T, Sato T, Glatter O, Horinouchi H, Kobayashi K, Tsuchida E.
    • Journal Title

      Bioconjug Chem.(Epub 2008 Jul 22) 19(8)

      Pages: 1556-1560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Enhanced radiation response of a solid tumor with the artificial oxygen carrier 'albumin-heme'2008

    • Author(s)
      Horinouchi H , Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K.
    • Journal Title

      Cancer Sci.(Epub 2008 Apr 21.) 99(6)

      Pages: 1274-1278

    • NAID

      10024007807

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifies tumor response to irradiation2008

    • Author(s)
      Yamamoto M, Izumi Y, Horinouchi H , Teramura Y, Sakai H, Kohno M, Watanabe M, Kawamura M, Adachi T, Ikeda E, Takeoka S, Tsuchida E, Kobayashi K.
    • Journal Title

      JSurg Res(Epub 2008Jan 17) 151(1)

      Pages: 48-54

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Enhanced radiation response of a solid tumor with the artificial oxygen carrier 'albumin-heme'2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K.
    • Journal Title

      Cancer Sci.(Epub 2008 Apr 21) 99(6)

      Pages: 1274-1278

    • NAID

      10024007807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Hemoglobin-vesicles as artificial oxygen carriers:Present situation and future vision.2008

    • Author(s)
      H.Sakai, K.Sou, H.Horinouchi, K.Kobayashi, E.Tsuchida.
    • Journal Title

      J.Intern.Med 263

      Pages: 4-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Enhanced radiation response of a solid tumor with the artificial oxygen carrier 'albumin-heme'.2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K.
    • Journal Title

      Cancer Science 99

      Pages: 1274-8

    • NAID

      10024007807

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591410
  • [Journal Article] Syndrome of inappropriate secretion of antidiuretic hormone after chemotherapy with vinorelbine2008

    • Author(s)
      Kuroda H, Kawamura M, Hato T, Kamiya K, Kawakubo M, Izumi Y, Watanabe M, Horinouchi H, Kobayashi K, Nakayama M.
    • Journal Title

      Cancer Chemother Pharmacol 62(2)

      Pages: 331-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Systemic Administration of Hemoglobin Vesicle Elevates Tumor Tissue Oxygen Tension and Modifies Tumor Response to Irradiation2008

    • Author(s)
      Yamamoto M, Izumi Y, Horinouchi H, Teramura Y, Sakai H, Kohno M, Watanabe M, Kawamura M, Adachi T, Ikeda E, Takeoka S, Tsuchida E, Kobayashi K.
    • Journal Title

      JSurg Res 2008(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] 多波長パルス分光法を用いたHb小胞体用パルスオキシメータに関する研究.2008

    • Author(s)
      須崎裕典, 酒井宏水, 小林直樹, 池田達彦, 堀之内宏久, ほか.
    • Journal Title

      人工血液 16

      Pages: 198-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Enhanced radiation response of a solid tumor with the artificial oxygen carrier 'albumin-heme'.2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K.
    • Journal Title

      Cancer Sci. 99(6) (Epub 2008 Apr 21)

      Pages: 1274-8

    • NAID

      10024007807

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591410
  • [Journal Article] NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers.2008

    • Author(s)
      H. Sakai, A. Sato, P. Sobolewski, S. Takeoka, J.A. Frangos, K. Kobayashi, M. Intaglietta, E. Tsuchida.
    • Journal Title

      Biochim. Biophys. Acta 1784

      Pages: 1441-1447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Occult injury in the residual lung after pneumonectomy in mice2008

    • Author(s)
      Tajima A, Kohno M, Watanabe M, Izumi Y, Tasaka S, Maruyama I, Miyasho T, Kobayashi K.
    • Journal Title

      Interact Cardiovasc Thorac Surg.(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Exacerbation of bleomycin-induced injury and fibros is bypneumonectomy in the residual lung of mice2008

    • Author(s)
      Kakizaki T, Kohno M, Watanabe M, Tajima A, Izumi Y, Miyasho T, Tasaka S, Fukunaga K, Maruyama I, Ishizaka A, Kobayashi K.
    • Journal Title

      Journal of Surgical Research (E-pub ahead)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Occult injury in the residual lung after pneumonectomy in mice.2008

    • Author(s)
      Tajima A, Kohno M, Watanabe M, Izumi Y, Tasaka s, Maruyama I, Miyasho T, Kobayashi K.
    • Journal Title

      Interact Cardiovasc Thorac Surg 7(6)

      Pages: 1114-1120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Enhanced radiation response of a solid tumor with the a rtificial 0xygen carrier'albumin-heme'.2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K.
    • Journal Title

      Cancer science 99

      Pages: 1274-1278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Systemic Administration of Hemoglobin Vesicle Elevates Tumor Tissue Oxygen Tension and Modifies Tumor Response to Irradiation.2008

    • Author(s)
      Yamamoto M, Izumi Y, Horinouchi H, Teramura Y, Sakai H, Kohno M, Watanabe M, Kawamura M, Adachi T, Ikeda E, Takeoka S, Tsuchida E, Kobayashi K
    • Journal Title

      J Surg Res E-pub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] An enhanced radiation response of solid tumor with the artificial oxygen carrier"allbumin-heme"(rHSA-FeP)2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Huang Y, Tsuchida E, Kobayashi K
    • Journal Title

      Cancer Science 99(6)

      Pages: 1274-1278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Hemoglobin-vesicles as artificial oxygen carriers: Present situation and future vision.2008

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Journal Title

      J. Intern. Med. 263

      Pages: 4-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Journal Article] Hyperthermia-enhanced tumor accumulation and antitumor efficacy of a doxorubicin-conjugate with a novel macromolecular carrier system in mice with non-small cell lung cancer.2007

    • Author(s)
      Oyama T, Kawamura M, Abiko T, Izumi Y, Watanabe M, Kumazawa E, Kuga H, Shiose Y, Kobayashi K
    • Journal Title

      Oncol Rep. 17(3)

      Pages: 653-659

    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] 縦隔へ向かって発育を示した鎖骨原発軟骨肉腫の1例2007

    • Author(s)
      江間俊哉, 江口圭介, 井澤菜緒子, 高橋祐介, 池田達彦, 朝倉啓介, 塚田紀理, 河野光智, 泉陽太郎, 渡辺真純, 堀之内宏久, 川村雅文, 小林紘一
    • Journal Title

      日本呼吸器外科学会雑誌 21巻6号

      Pages: 850-853

    • NAID

      110006452377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Haemoglobin-vesicles as artificial oxygen carriers : present situation and future visions2007

    • Author(s)
      Sakai H, Sou K, Horinouchi H , Kobayashi K, Tsuchida E.
    • Journal Title

      J Intern Med(Epub 2007 Nov 27. Review) 263

      Pages: 4-15

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Influence of O(2)-carrying plasma hemoprotein "albumin-heme" on complement system and platelet activation in vitro and physiological responses to exchange transfusion2007

    • Author(s)
      Komatsu T, Huang Y, Wakamoto S, Abe H, Fujihara M, Azuma H, Ikeda H, Yamamoto H, Horinouchi H , Kobayashi K, Tsuchida E.
    • Journal Title

      J Biomed Mater Res A. 81(4)

      Pages: 821-826

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Prediction of anti-tumour effect of thermochemotherapy with in vitro thermochemosensitivity testing for non-small cell lung cancer2007

    • Author(s)
      Abiko T, Kawamura M, Izumi Y, Oyama T, Saito Y, Kobayashi K.
    • Journal Title

      Int J Hyperthermia. 23(3)

      Pages: 267-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] One-year observation of Wistar rats after infusion of Hb-vesicles (Artificial oxygen carriers).2007

    • Author(s)
      H.Sakai, H.Horinouchi, E.Tsuchida, K.Kobayashi
    • Journal Title

      Artif. Cells Blood Substitutes Biotechnol. 35

      Pages: 81-91

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] 術前化学療法後に外科的切除し得た前縦隔原発Germ cell tumor with somatic typemalignancy の1 例2007

    • Author(s)
      高橋祐介, 池田達彦, 河野光智, 堀之内宏久, 林雄一郎, 小林紘一, 仁木利郎
    • Journal Title

      肺癌 47巻6号

      Pages: 793-794

    • NAID

      110006475037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] One-year observation of Wistar rats after infusion of Hb-vesicles (Artificial oxygen carriers).2007

    • Author(s)
      H.Sakai, H.Horinouchi, E.Tsuchida, K.Kobayashi.
    • Journal Title

      Artif. Cells Blood Substitutes Biotechnol. 35(in press)

    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] The short-term efficacy of fibrin glue combined with absorptive sheet material in visceral pleural defect repair2007

    • Author(s)
      Gika M, Kawamura M, Izumi Y, Kobayashi K.
    • Journal Title

      Interact Cardiovasc Thorac Surg 6(1)

      Pages: 12-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Hemostatic efficacy of a recombinant thrombin-coated polyglycolic acid sheet coupled with liquid fibrinogen, evaluated in a canine model of pulmonary arterial hemorrhage2007

    • Author(s)
      Izumi Y, Gika M, Shinya N, Miyabashira S, Imamura T, Nozaki C, Kawamura M, Kobayashi K.
    • Journal Title

      J Trauma.(discussion 787) 63(4)

      Pages: 783-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] ヘモグロビン小胞体(HbV)-リコンビナントアルブミン分散溶液による40%交換輸血 : ラット脾臓内HbV代謝と造血に関する2週間の観察(論文記事 : secondary publication).2007

    • Author(s)
      酒井宏水, 堀之内宏久, 山本学, 池田栄二, 武岡真司, 高折益彦, 土田英俊, 小林紘一
    • Journal Title

      日本輸血細胞治療学会誌 53

      Pages: 47-55

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Effect of hemoglobin vesicle, a cellular-type artificial oxygen carrier, on middle cerebral artery occlusion- and arachidonic acid-induced stroke models in rats2007

    • Author(s)
      Komatsu H, Furuya T, Sato N, Ohta K, Matsuura A, Ohmura T, Takagi S, Matsuura M, Yamashita M, Itoda M, Itoh J, Horinouchi H , Kobayashi K.
    • Journal Title

      Neurosci Lett(Epub 2007 Jun 2) 421(2)

      Pages: 121-125

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] 術前化学療法後に外科的切除し得た前縦隔原発Germ cell tumor with somatic type mahgnancyの1例2007

    • Author(s)
      高橋 祐介, 池田 達彦, 河野 光智, 堀之内 宏久, 林雄 一郎, 小林 紘一, 仁木 利郎
    • Journal Title

      肺癌 47

      Pages: 793-794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] 縦隔へ向かって発育を示した鎖骨原発軟骨肉腫の1例2007

    • Author(s)
      江間 俊哉, 江口 圭介, 井澤 菜緒子, 高橋 祐介, 池田 達彦, 朝倉 啓介, 塚田 紀理, 河野 光智, 泉 陽太郎, 渡辺 真純, 堀之内 宏久, 川村 雅文, 小林 紘一
    • Journal Title

      日本呼吸器外科学会雑誌 21

      Pages: 850-853

    • NAID

      110006452377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] One-year observation of Wistar rats after infusion of Hb-vesicles (Artificial oxygen carriers).2007

    • Author(s)
      H.Sakai, H.Horinouchi, E.Tsuchida, K.Kobayashi.
    • Journal Title

      Artif.Cells Blood Substitutes Biotechnol. 35

      Pages: 81-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] One-year observation of Wistar rats after intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers)2007

    • Author(s)
      Sakai H, Tsuchida E, Horinouchi H , Kobayashi K.
    • Journal Title

      Artif Cells Blood Substit Immobil Biotechnol 35(1)

      Pages: 81-91

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Phase II trial of gemcitabine and docetaxel in patients with completely resected stage IIA-IIIA non-small-cell lung cancer2007

    • Author(s)
      Kawamura M, Eguchi K, Izumi Y, Yamato Y, Koike T, Sakaguchi H, Hada E, Kobayashi K.
    • Journal Title

      Cancer Chemother Pharmacol 60(4)

      Pages: 495-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Cross-linked poly (gamma-glutamic acid) attenuates peritoneal adhesion in arat model2007

    • Author(s)
      Izumi Y, Yamamoto M, Kawamura M, Adachi T, Kobayashi K.
    • Journal Title

      Surgery 141(5)

      Pages: 678-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Hyperthermia-enhanced tumor accumulation and antitumor efficacy of a doxorubicin-conjugate with a novel macromolecular carrier system in mice with non-small cell lung cancer2007

    • Author(s)
      Oyama T, Kawamura M, Abiko T, Izumi Y, Watanabe M, Kumazawa E, Kuga H, Shiose Y, Kobayashi K.
    • Journal Title

      Oncol Rep. 17(3)

      Pages: 653-659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Large chondrosarcoma of the rib invading the mediastinum an the spine.2006

    • Author(s)
      Morioka H, Yabe H, Kaneko S, Takaishi H, Ueda T, Watanabe M, Kobayashi K, Toyama Y
    • Journal Title

      J Thorac Cardiovasc Surg. 132(4)

      Pages: 986-987

    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] PEGylated albumin-heme as an oxygen-carrying plasma expander : Exchange transfusion into acute anemia rat model2006

    • Author(s)
      Huang Y, Komatsu T, Yamamoto H, Horinouchi H , Kobayashi K, Tsuchida E.
    • Journal Title

      Biomaterials 27(25)

      Pages: 4477-4483

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Hemoglobin-vesicles as atransfusion alternative2006

    • Author(s)
      Tsuchida E, Sakai H, Horinouchi H , Kobayashi K.
    • Journal Title

      Artif Cells Blood Substit Immobil Biotechnol(Review) 34(6)

      Pages: 581-588

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] PEGylated albumin-heme as an oxygen-carrying plasma expander : Exchange transfusion into acute anemia rat model.2006

    • Author(s)
      Huang Y, Komatsu T, Yamamoto H, Horinouchi H, Kobayashi K, Tsuchida E
    • Journal Title

      Biomaterials 27・25

      Pages: 4477-4483

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Hemoglobin-Vesicles as a Molecular Assembly : Characteristics of Preparation Process and Performances as Artificial Oxygen Carriers.2006

    • Author(s)
      H.Sakai, K.Sou, S.Takeoka, K.Kobayashi, E.Tsuchida
    • Journal Title

      Blood Substitutes (Ed.By Robert M.Winslow, Elsevier)(Chapt.) 44

      Pages: 514-522

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution : degradation of HbV and erythropoiesis in a rat spleen for 2 weeks.2006

    • Author(s)
      H.Sakai, H.Horinouchi, M.Yamamoto, E.Ikeda, S.Takeoka, M.Takaori, E.Tsuchida, K.Kobayashi
    • Journal Title

      Transfusion 46

      Pages: 339-347

    • NAID

      120001107019

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Early pulmonary resection for Mycobacterium avium complex lung disease treated with macrolides and quinolones2006

    • Author(s)
      Watanabe M, Hasegawa N, Ishizaka A, Asakura K, Izumi Y, Eguchi K, Kawamura M, Horinouchi H, Kobayashi K.
    • Journal Title

      Ann Thorac Surg 81(6)

      Pages: 2026-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Prognosis of surgically treated thymic epithelial tumors2006

    • Author(s)
      Horinouchi H, Asakura K, Kimura Y, Takeuchi K, Kawamura M, Watanabe M, Eguchi K, Kobayashi K
    • Journal Title

      Nippon Geka Gakkai Zasshi 107(6)

      Pages: 262-267

    • NAID

      110004852494

    • Data Source
      KAKENHI-PROJECT-18599007
  • [Journal Article] Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution : degradation of HbV and erythropoiesis in a rat spleen for 2 weeks.2006

    • Author(s)
      H.Sakai, H.Horinouchi, M.Yamamoto, E.Ikeda, S.Takeoka, M.Takaori, E.Tsuchida, K.Kobayashi.
    • Journal Title

      Transfusion 46

      Pages: 339-347

    • NAID

      120001107019

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Hemoglobin-vesicles as a transfusion alternative.2006

    • Author(s)
      E.Tsuchida, H.Sakai, H.Horinouchi, K.Kobayashi
    • Journal Title

      Artif. Cells Blood Substitutes Biotechnol. 34

      Pages: 581-588

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] 胸腺上皮性腫瘍の外科治療成績2006

    • Author(s)
      堀之内宏久, 朝倉啓介, 木村吉成, 竹内健, 川村雅文, 渡辺真純, 江口圭介, 小林紘一
    • Journal Title

      日本外科学会雑誌 107・6

      Pages: 262-267

    • NAID

      110004852494

    • Data Source
      KAKENHI-PROJECT-18591560
  • [Journal Article] Hemoglobin-vesicles as a transfusion alternative.2006

    • Author(s)
      E.Tsuchida, H.Sakai, H.Horinouchi, K.Kobayashi.
    • Journal Title

      Artif.Cells Blood Substitutes Biotechnol. 34

      Pages: 581-588

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Safety and Efficacy of Hemoglobin-Vesicles and Albumin-Hemes.2005

    • Author(s)
      K.Kobayashi, H.Horinouchi, M.Watanabe, Y.Izumi, Y.Teramura, A.Nakagawa, Y.Huang, K.Sou, H.Sakai, T.Komatsu, S.Takeoka, E.Tsuchida.
    • Journal Title

      Artificial Oxygen Carrier : Its Front Line, Keio University International Symposia for Life Sciences and Medicine(Eds.by K.Kobayashi, E.Tsuchida, H.Horinouchi.)(Springer-Verlag) Vol.12

      Pages: 1-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Oxygen Infusions (Hemoglobin-Vesicles and Albumin-Hemes) Based on Nano-Molecular Sciences.2005

    • Author(s)
      E.Tsuchida, H.Sakai, T.Komatsu, S.Takeoka, Y.Huang, K.Sou, A.Nakagawa, Y.Teramura, K.Kobayashi
    • Journal Title

      Polymers Adv. Technol. 16

      Pages: 73-83

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Hemoglobin-vesicles (HbV) as Artificial Oxygen Carriers.2005

    • Author(s)
      H.Sakai, K.Sou, S.Takeoka, K.Kobayashi, E.Tsuchida.
    • Journal Title

      Artificial Oxygen Carrier : Its Front Line, Keio University International Symposia for Life Sciences and Medicine(Eds.by K.Kobayashi, E.Tsuchida, H.Horinouchi)(Springer-Verlag) Vol.12

      Pages: 135-168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Oxygen Infusions (Hemoglobin-Vesicles and Albumin-Hemes) Based on Nano-Molecular Sciences.2005

    • Author(s)
      E.Tsuchida, H.Sakai, T.Komatsu, S.Takeoka, Y.Huang, K.Sou, A.Nakagawa, Y.Teramura, K.Kobayashi.
    • Journal Title

      Polymers Adv.Technol. 16

      Pages: 73-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Physiologic capacity of reticuloendothelial system for degradation of hemoglobin-vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days.2004

    • Author(s)
      H.Sakai, Y.Masada, H.Horinouchi, E.Ikeda, K Sou, S.Takeoka, M.Suematsu, M.Takaori, K.Kobayashi, E.Tsuchida
    • Journal Title

      J. Pharmacol. Exp. Ther. 311

      Pages: 874-884

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Hemorrhagic shock resuscitation with an artificial oxygen carrier Hemoglobin Vesicle (HbV) maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor alpha (TNFa).2004

    • Author(s)
      A.Yoshizu, Y.Izumi, S.Park, H.Sakai, S.Takeoka, H.Horinouchi, E.Ikeda, E.Tsuchida, K.Kobayashi.
    • Journal Title

      ASAIO J. 50

      Pages: 458-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model.2004

    • Author(s)
      H.Sakai, H.Horinouchi, Y.Masada, S.Takeoka, M.Takaori, K.Kobayashi, E.Tsuchida
    • Journal Title

      Biomaterials 25

      Pages: 4317-4325

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model.2004

    • Author(s)
      H.Sakai, H.Horinouchi, Y.Masada, S.Takeoka, M.Takaori.K.Kobayashi, E.Tsuchida.
    • Journal Title

      Biomaterials 25

      Pages: 4317-4325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Hemorrhagic shock resuscitation with an artificial oxygen carrier Hemoglobin Vesicle (HbV) maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor alpha (TNF α).2004

    • Author(s)
      A.Yoshizu, Y.Izumi, S.Park, H.Sakai, S.Takeoka, H.Horinouchi, E.Ikeda, E.Tsuchida, K.Kobayashi
    • Journal Title

      ASAIO J. 50

      Pages: 458-463

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Metabolism of hemoglobin-vesicles(artificial oxygen carriers) and their influence on organ functions in a rat model.2004

    • Author(s)
      Sakai H, Horinouchi H, Takeoka S, Takaori M, Kobayashi K, Tsuchida E
    • Journal Title

      Biomaterials 25

      Pages: 4317-4325

    • Data Source
      KAKENHI-PROJECT-16300162
  • [Journal Article] Exacerbation of bleomycin-induced injury and fibrosis by pneumonectomy in the residual lung of mice

    • Author(s)
      Kakizaki T, Kohno M, Watanabe M, Tajima A, Izumi Y, Miyasho T, Tasaka S, Fukunaga K, Maruyama I, Ishizaka A, Kobayashi K.
    • Journal Title

      J Surg Res. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Presentation] Characteristics of hemoglobin vesicles as a cellular type artificial oxygen carrier2011

    • Author(s)
      H. Sakai, H. Horinouchi, K. Kobayashi
    • Organizer
      XIII International Symposium on Blood Substitutes and Oxygen Therapeutics
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Presentation] HEMOGLOBIN-VESICLES, ARTIFICIAL RED CELLS, AS O_2 AND CO CARRIERS FOR CYTOPROTECTION2010

    • Author(s)
      H. Sakai, H. Horinoichi, K. Kobayashi, E. Tsuchida
    • Organizer
      The 5th SBE International Conference on Bioengineering and Nanotechnology
    • Place of Presentation
      Biopolis, Singapore
    • Data Source
      KAKENHI-PROJECT-22300161
  • [Presentation] Physicochemical characteristics of Hb-Vesicles as RBC substitutes2009

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Organizer
      XII International Symposium on Blood Substitutes
    • Place of Presentation
      Parma
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] マウス出血性ショック時における人工赤血球投与の脳酸素分圧への影響2008

    • Author(s)
      冨田裕, 鳥海春樹, TatarishviliJemal, 冨田稔, 畝川美悠紀, 酒井宏水, 土田英俊, 堀之内宏久, 小林紘一, 鈴木則宏
    • Organizer
      第20回脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-06
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] Molecular artificial oxygen carrier“albumin-heme"can en hance radiation response of solid tumor. Experimental in vivo study.2008

    • Author(s)
      Horinouchi H, Yamamoto H, Komatsu T, Yubin Huang, Tsuchida E, Kobayashi K.
    • Organizer
      36^<th> Annual Conference of International Sosiety on Oxygen Transport to Tissue
    • Place of Presentation
      Sapporo Prince Hotel
    • Year and Date
      2008-08-05
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] Enhanced radiation response by artificial oxygen carrier2008

    • Author(s)
      Hirohisa Horinouchi, Hisashi Yamamoto, Takayo Oba, Mizuha Haraguchi, Koichi Kobayashi, Teruaki Komatsu, Eishun Tsuchida
    • Organizer
      ISOTT2008
    • Place of Presentation
      Sapporo
    • Year and Date
      2008-08-05
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] 輸血代替としての利用法 Beagle 犬を用いた40%脱血ショックにおけるHb 小胞体の蘇生効果および中長期生存後の安全性の検討2008

    • Author(s)
      池田達彦, 堀之内宏久, 井澤菜緒子, 河野光智, 泉陽太郎, 渡辺真純, 川村雅文, 宗慶太郎, 酒井宏水, 土田英俊, 小林紘一
    • Organizer
      第15回日本血液代替物学会年次大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] 輸血代替としての利用法マウス肺切除+周術期出血モデルでのヘモグロビン小胞体投与の有効性の検討2008

    • Author(s)
      河野光智, 竹田貴, 堤恭介, 池田達彦, 泉陽太郎, 渡辺真純, 堀之内宏久, 小林紘一, 酒井宏水, 土田英俊
    • Organizer
      第15回日本血液代替物学会年次大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] Hb-Vesicle: A Cellular Hb-Based Oxygen Carrier that Fulfills the Physiological Roles of the RBC Structure2008

    • Author(s)
      H. Sakai, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida
    • Organizer
      ISOTT 2008 (Intenational Society on Oxygen Transport to Tissue)
    • Place of Presentation
      Sapporo Prince Hotel
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] 輸血代替としての利用法 腎傷害による制御不能出血モデルに対するヘモグロビン小胞体の蘇生効果2008

    • Author(s)
      勢司泰久, 堀之内宏久, 相川直樹, 酒井宏水, 土田英俊, 小林紘一
    • Organizer
      第15回日本血液代替物学会年次大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] 輸血代替としての利用法 血管損傷による制御不能出血性ショックの蘇生 人工酸素運搬体の効果について2008

    • Author(s)
      堀之内宏久, 勢司泰久, 河野光智, 泉陽太郎, 酒井宏水, 小林紘一, 土田英俊
    • Organizer
      第15回日本血液代替物学会年次大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-18591560
  • [Presentation] Hemoglobin-vesicles as O2- and CO carriers2008

    • Author(s)
      H. Sakai, H. Horinouchi, K. Kobayashi, E. Tsuchida
    • Organizer
      The 6th Current Issues on Blood Substitute Research
    • Place of Presentation
      Keio University Shinanomachi Campus
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] Fluid resuscitation with Hemoglobin-vesicles(Artificial Red Cells) in hemorrhaged rats and profiles of recovery for 14 days.2007

    • Author(s)
      H. Sakai, H. Horinouchi, E. Tsuchida, K. Kobayashi.
    • Organizer
      53rd Annual Conference of ASAIO
    • Place of Presentation
      Chicago,USA
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] ヘモグロビン小胞体と各種代用血漿剤の併用に関する検討2007

    • Author(s)
      酒井 宏水、佐藤 敦、武岡 真司、堀之内 宏久、高折 益彦、小林 紘一、土田 英俊
    • Organizer
      第14回日本血液代替物学会年次大会
    • Place of Presentation
      慶應義塾大学
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] Hemoglobin vesicles as artificial oxygen carriers: Interactions with ligand molecules in the production process and in blood circulation.2007

    • Author(s)
      H. Sakai, A. Sato, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Organizer
      The 11th International Symposium on Blood Substitutes
    • Place of Presentation
      Beijing,China
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] Hb-vesicles as artificial oxygen carriers: Interactions with ligand molecules in the production process and in blood circulation.2007

    • Author(s)
      H. Sakai, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Organizer
      2007 Joint Congress of the 45th Annual Meeting of the Japanese Society for Artificial Organs (JSAO) and The 2nd Meeting of the International Federation for Artificial Organs (IFAO)
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] Hb-vesicles as artificial oxygen carriers:Intenactions with ligand molecules in the production process and in blood circulation.2007

    • Author(s)
      H. Sakai, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Organizer
      2007 Joint Congress of the 45th Annual Meeting of JSAO and The 2nd Meeting of IFAO
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-19300164
  • [Presentation] 実験的胸膜播種モデルにおける原発巣由来ストローマ細胞の関与についての検討2007

    • Author(s)
      河野 光智, 羽藤 泰, 泉 陽太郎, 渡辺 真純, 川村 雅文, 堀之内 宏久, 小林 紘一
    • Organizer
      第48回 日本肺癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-11-08
    • Data Source
      KAKENHI-PROJECT-18599007
  • [Presentation] Hemoglobin vesicles as artificial oxygen carriers: Interactions with ligand molecules in the production process and in blood circulation.2007

    • Author(s)
      H. Sakai, A. Sato, K. Sou, H. Horinouchi, K. Kobayashi, E. Tsuchida.
    • Organizer
      The 11th International Symposium on Blood Substitutes
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-19300164
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