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SHIMADA Hideo  島田 秀夫

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Researcher Number 80095611
Other IDs
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Affiliation (based on the past Project Information) *help 2011 – 2012: 兵庫県立大学, 大学院・生命理学研究科, 教授
2010 – 2011: 兵庫県立大学, 生命理学研究科, 教授
2008 – 2009: University of Hyogo, 大学院・生命理学研究科, 教授
2007: Keio University, 医学部, 准教授
2005 – 2006: 慶應義塾大学, 医学部, 助教授 … More
2000 – 2003: 慶應義塾大学, 医学部, 助教授
2001: 慶応大学, 医学部, 助教授
1998 – 1999: 慶応義塾大学, 医学部, 助教授
1995 – 1997: 慶應義塾大学, 医学部, 助教授
1996: KEIO UNIVERSITY,SCHOOL OF MEDICINE ASSOCIATE PROFESSOR, 医学部, 助教授
1996: 慶應儀塾大学医学部, 助教授
1995 – 1996: 慶応義塾大学, 医学部, 助教授
1990 – 1994: 慶應義塾大学, 医学部, 講師
1988: School of Medicine, Keio University, 医学部, 助手
1986 – 1987: 慶應義塾大学, 医学部, 助手
1986: 慶応大, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Biophysics / 生物物性学 / Science and Engineering / Biophysics
Except Principal Investigator
Bioorganic chemistry / Functional biochemistry / 生物物性学 / Science and Engineering / Structural biochemistry
Keywords
Principal Investigator
部位特異的アミノ酸置換 / プロトンポンプ / ミオグロビン / 過酸化水素 / カンファー / アミノ酸置換 / ミトコンドリア / チトクロム酸化酵素 / シトクロームP450 / Paracoccus denitrificans … More / 水素イオン供給 / 膜タンパク質複合体 / HeLa細胞 / チトクロムc酸化酵素 / 膜蛋白質 / X線結晶構造解析 / 水 / 水素結合のネットワーク / プロトン供給 / プチダレドキシン / 大腸菌 / O-O結合開裂反応 / プロトン / 酸触媒 / 酸素化型 / チトクロームP450 / 酸素 / Nucleotide Sequence / Oxygenated Myoglobin / Yeast / Expression / Conformer / cDNA / Myoglobin / Bovine / タンパク質工学 / 部位特異的変異 / クローニング / コンフォマー / 酸素チャンネル / site-directed mutagenesis / O-O bond scission / dioxygen / hydrogen bonding network / X-ray structure / proton / cytochrome P450 / ハイドロペルオキシ型 / ペプチド / Zn^<2+> / プロリン / 酸素のO-O開裂 / X-線構造 / 水素イオン / チトクロムP450 / cell-free protein synthesis / membrane protein / proton pump / cytochrome oxidase / myoglobin / heme / gene therapy / composite biocatalyst / 亜硝酸イオン還元酵素 / ペルオキシゲナーゼ / オーダーメイド / シトクロムP450 / ペルオキシダーゼ / 亜硝酸還元酵素 / ポルフィセン / 膜たんぱく質複合体 / 無細胞蛋白合成系 / ヘム / 遺伝子治療 / コンポジット生体触媒 / ELECTRON TRANSFER / ARTIFICIAL AMINO ACID / O-O BOND CLEAVAGE / ARTIFICIAL ENZYME / ACID CATALYST / OXYGENATEDFORM / CAMPHOR / CYTOCHROME P450 / 非天然型アミノ酸 / 電子伝達 / 人工アミノ酸 / 人工酵素 / N-acetylcysteine / 無細胞タンパク質合成系 / ウシ心筋 / 機能 / 動態 / 核酸の構造 / タンパク質 / ウシチトクロム酸化酵素発現系 / 酸素還元 / シグナル伝達系 / 水素結合ネットワーク / プロトン輸送 / 培養細胞 / ペプチド結合 / 無細胞転写翻訳系 / チトクロムP450cam / ヘムプロピオン酸基 / ヘムa / X線構造 / エネルギー変換 / EPR / 水素イオン輸送 / X-線結晶構造解析 / 無細胞たんぱく合成 / シトクロム酸化酵素 / カンフア- / スレオニン / 部位特異的変異法 / 水酸化反応 / 一原子酸素添加酵素 / チトクロ-ムPー450 … More
Except Principal Investigator
Site-directed mutagenesis / ミオグロビン / ペルオキシダーゼ / XANES / P450cam / ヘム蛋白質 / ヘム / COMPOUND I / PEG-HRP / Cytochrome P450 / シトクロムP450 / peroxidase / Peroxidase / Hemoglobin / Myoglobin / Laser-Photolysis / Time-Resolved EXAFS / X線吸収スペクトル;ヘモグロビン / 螢光X線 / ミオグロビンCO錯体 / レーザーフォトリシス / 放射光 / 生体高分子の動的構造解析 / フラッシュフォトリシス / EXAFS / 動的構造解析 / チトクロムP450 / ヘモグロビン / レーザフォトリシス / 時間分解EXAFS / prosthetic group / carbon monoxide affinity / dioxygen affinit / iron porphyicene / artificial heme / reconstitution / myoglobin / 自動酸化 / 酸素センサー / 酸素錯体 / タンパク質機能化 / 中間体 / グアイアコール / 過酸化水素 / タンパク質再構成 / ペプオキシゲナーゼ / ペルキオシダーゼ / タンパク質機能変換 / 鉄コロール / ペルオキシダーゼ活性 / ヘムタンパク質 / 補欠分子 / 一酸化炭素親和性 / 酸素親和性 / 鉄ポルフィセン / 人工ヘム / 再構成 / built-in cofactor / heme / flavin / cobalamin / pyridoxal phosphate / structure activity relationship / coenzyme / composite biocatalyst / キノヘムプロテイン / ビルトイン補酵素 / フラビン / コバラミン / ピリドキサルリン酸 / 構造活性相関 / 補酵素 / コンポジット生体触媒 / Hydrogen bonding / Threonine / Dioxygen-bond cleavage / Artificial amino acids / Acid-base catalyst / Activation of molecular oxygen / Cytochome P450 / スレオニン / 人工アミノ酸 / O-O結合開裂反応 / 酸触媒 / 酸素活性化 / HEME / MYOGLOBIN / PEROXIDASE / ハイブリッド / ミューテーション / Oxgen Activation mechanism / NADPH-oxidase / Monooxygenases / Oxygenases / Activated forms of oxygen / Oxygen metabolism / NADPHオキシダーゼ / NADPHオキシターゼ / 部位特異的アミノ酸置換 / 酸素添加酵素 / オキシゲナーゼ / 活性酸素 / 酸素の活性化 / 振動分光解析 / X線結晶構造解析 / 金属タンパク質 / 膜タンパク質 / 生体エネルギー変換 / SoxR / チトクロムP450nor / チトクロムP450cam / ヘムオキシゲナーゼ / Sox R / チトクロム P450 nor / チトクロムP450 cam / ADP-リボシル化 / ハムオキシゲナーゼ / グアニル酸シクラーゼ / X-線結晶解析 / P450 / ヘム結合性ストレス蛋白 / SOXR / 鉄イオウタンパク質 / グアニル酸シクララーゼ / NO合成酵素(NOS) / HBP23 / X線結晶構造 / キサンチン脱水素酵素 / 電子スピン共鳴 / 金属フラビン酵素 / NO合成酵素 / キサンチン酸化酵素 Less
  • Research Projects

    (21 results)
  • Research Products

    (47 results)
  • Co-Researchers

    (40 People)
  •  Elucidation of the mammalian mitochondrial respiration mechanism at the atomic level.

    • Principal Investigator
      YOSHIKAWA Shinya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Hyogo
  •  ウシチトクロム酸化酵素のプロトン輸送系の変異体解析Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Hyogo
  •  Studies by molecular biological methods on proton pumping mechanisms of bovine heart and bacterial cytochrome c oxidasesPrincipal Investigator

    • Principal Investigator
      SHIMADA Hideo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      University of Hyogo
  •  変異体の機能と構造との解析によるチトクロム酸化酵素のプロトンポンプ機構の研究Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  チトクロム酸化酵素によるプロトンポンプ機構の研究Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Extreme Functionalization of Hemoproteins upon the Direct Chemical Modification to Heme Framework

    • Principal Investigator
      HAYASHI Takashi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Kyushu University
  •  カムオペロンの末端酸化酵素と電子供与体たんぱく質の複合体Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Molecular Design and Evolution Engineering for Compositc Biochatalysts

    • Principal Investigator
      TORAYA Tetsuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      KYOTO UNIVERSITY
  •  Development of heme-based highly efficient biocatalystsPrincipal Investigator

    • Principal Investigator
      SHIMADA Hideo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      KEIO UNIVERSITY
  •  Studies on the entry site of protons necessary for the monooxygenation reaction catalyzed by cytochrome P450camPrincipal Investigator

    • Principal Investigator
      SHIMADA Hideo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      KEIO UNIVERSITY
  •  カンファー水酸化酵素P450と鉄イオウたんぱく質の複合体:複合体形成によって誘導されるP450の活性型構造と誘導機構の解明Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  無細胞たんぱく合成系でのチトクロム酸化酵素の機能発現: 人工アミノ酸の部位特異的導入法を利用したプロトン能動輸送機構の解析を目指してPrincipal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biophysics
    • Research Institution
      Keio University
  •  金属蛋白質による情報変換

    • Principal Investigator
      西野 武士
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nippon Medical School
  •  CHARACTERIZATION OF UNSTABLE INTERMEDIATES OF HEME ENZYMES BY UTILIZING ENZYMES AND THEIR HYBRIDES

    • Principal Investigator
      WATANABE Yoshihito
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      OKAZAKI NATIONAL RESEARCH INSTITUTES
  •  MECHANISM FOR OXYGEN ACTIVATION BY CYTOCHROME P450cam

    • Principal Investigator
      ISHIMURA Yuzuru
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      SCHOOL OF MEDICINE,KEIO UNIVERSITY
  •  Oxygen activation mechanisms in cytochrome P450-and NADPH oxidase-catalyzed reactions

    • Principal Investigator
      ISHIMURA Yuzuru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Keio University
  •  Elucidation for the catalytic function of cytochrome P450cam by site-specific incorporation of natural and unnatural amino acid.Principal Investigator

    • Principal Investigator
      SHIMADA Hideo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      KEIO UNIVERSITY
  •  チトクロームP450camの構造と機能の相関ー活性部位に位置する酵素反応に必須のアミノ酸残基の役割Principal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      生物物性学
    • Research Institution
      Keio University
  •  チトクロ-ムP450camにおける酸素ポケットの構造と機能の相関の解明ーアミノ酸置換による機能変換の解析ーPrincipal Investigator

    • Principal Investigator
      島田 秀夫
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      生物物性学
    • Research Institution
      Keio University
  •  Investigation on Ligand Active Conformer of Bovine Myoglobin.Principal Investigator

    • Principal Investigator
      SHIMADA Hideo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      生物物性学
    • Research Institution
      Keio University
  •  Time-resolved EXAFS method for analyses of dynamical structure of biopolymers

    • Principal Investigator
      IIZUKA Tetsutaro
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      生物物性学
    • Research Institution
      The Institute of Physicaland Chemical Research

All 2012 2011 2010 2009 2005 2004 2003 2001 Other

All Journal Article Presentation

  • [Journal Article] Characterization by mutagenesis analysis of putative proton transfer pathway, D-pathway of bovine heart cytochrome c oxidase2012

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Journal Title

      生物物理

      Volume: 151

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Mutagenesis analyses of D-pathway of bovine heart cytochrome c oxidase suggest that the pathway does not transfer the pumping protons2012

    • Author(s)
      Ryohta Aminaka, Mai Itoh, Kunitoshi Shimokata, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Journal Title

      Biochim Biophys Acta

      Volume: 1817 Pages: 93-93

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Diversity in proton pumping mechanism of the terminal oxidases2011

    • Author(s)
      Hideo Shimada, Shinya Yoshikawa
    • Journal Title

      生物物理

      Volume: 151

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Mutagenesis studies on the functional mechanism of cytochrome c oxidase and cytochrome P450cam2010

    • Author(s)
      Hideo Shimada
    • Journal Title

      生物物理

      Volume: 50

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Mutagenesis studies on D-pathway function of bovine heart cytochrome c oxidase2010

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Journal Title

      Biochimica Biophysica Acta

      Volume: 1797 Pages: 93-94

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Cell-free synthesis of cytochrome c oxidase, a multicomponent membrane protein2010

    • Author(s)
      Yukie Katayama, Kunitoshi Shimokata, Makoto Suematsu, Takashi Ogura, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Journal Title

      J . Bioenerg. Biomembr

      Volume: 42 Pages: 235-240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Mutagenesis studies on the functional roles of possible proton transfer pathwaysin bovine heart cytochrome c oxidase2009

    • Author(s)
      Shimada, Hideo, et al.
    • Journal Title

      J.Biol.Inorg.Chem. 14(Suppl 1)

    • Data Source
      KAKENHI-PROJECT-20051023
  • [Journal Article] Mutagenesis studies on the functional roles of possible proton transfer pathways in bovine heart cytochrome c oxidase2009

    • Author(s)
      Hideo Shimada
    • Journal Title

      J. Biol. Inorg. Chem

      Volume: 14(Suppl 1)

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] Mutagenesis studies on the functional roles of possible proton transfer pathways in bovine heart cytochrome c oxidase2009

    • Author(s)
      Shimada, Hideo, et al.
    • Journal Title

      J.Biol.Inorg.Chem. 14(Suppl 1)

    • Data Source
      KAKENHI-PROJECT-21370073
  • [Journal Article] ウシ・ヒト雑種チトクロム酸化酵素のヒト培養細胞での発現2005

    • Author(s)
      島田秀夫
    • Journal Title

      生物物理 45

      Pages: 324-324

    • Data Source
      KAKENHI-PROJECT-17053025
  • [Journal Article] Vibronic coupling between Soret and higher-energy excited states in iron(II) porphyrins : Raman excitation profiles of A_<2g> modes in the Soret region.2004

    • Author(s)
      Egawa, T., Suzuki, N., Dokoh, T., Higuchi, T., Shimada, H., Kitagawa, T., Ishimura, Y.
    • Journal Title

      J.Phys.Chem. 108

      Pages: 568-577

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Refolding Processes of Cytochrome P450_<cam> from Ferric and Ferrous Acid Forms to the Native Conformation : Formations of Folding Intermediates with Non-Native Heme Coordination State.2004

    • Author(s)
      Egawa, T., Hishiki, T., Ichikawa, Y., Kanamori, Y., Shimada, H., Takahashi, S., Kitagawa, T., Ishimura, Y.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 32008-32017

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Infrared Spectroscopic and Mutational Studies on Putidaredoxin-induced Conformational Changes in Ferrous CO-P450cam.2003

    • Author(s)
      Nagano, N., Shimada, H., Tarumi, A., Hishiki, T., Kimata-Ariga, Y., Egawa, T., Suematsu, M., Park, S-Y., Adachi, S., Shiro, Y., Ishimura, Y.
    • Journal Title

      Biochemistry 42

      Pages: 14507-14514

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Kinetic and Spectroscopic Characterization of Hydroperoxy Compound in the Reaction of Native Myoglobin with Hydrogen Peroxide.2003

    • Author(s)
      Egawa, T., Yoshioka, S., Takahashi, S., Hori, H., Nagano, S., Shimada, H., Ishimori, K., Morishima, I., Suematsu, M., Ishimura, Y.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 41597-41606

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] NMR Study on the Structural Changes of Cytochrome P450cam upon the Complex Formation with Putidaredoxin : Functional Significance of the Putidaredoxin-induced Structural Changes.2003

    • Author(s)
      Tosha, T., Yoshioka, S., Takahashi, T., Ishimori, K., Shimada, H., Morishima, I.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 39809-39821

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Elucidation of the differences between the 430- and 455-nm absorbing forms of P450-isocyanide adducts by resonance Raman spectroscopy.2001

    • Author(s)
      Tomita, T., Ogo, S., Egawa, T., Shimada, H., Okamoto, N., Imai, Y., Watanabe, Y., Ishimura, Y., Kitagawa, T.
    • Journal Title

      J.Biol.Chem. 276

      Pages: 36261-36267

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Cytochrome P450cam-putidaredoxin interaction.2001

    • Author(s)
      Shimada, H., Nagano, S., Hori, H., Ishimura, Y.
    • Journal Title

      J.Inorg.Biochem. 83

      Pages: 255-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Journal Article] Cytochrome P450cam-putidaredoxin interaction2001

    • Author(s)
      Shimada, H., et al.
    • Journal Title

      J.Inorg.Biochem. 83

      Pages: 255-260

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13680750
  • [Presentation] Mutagenesis analyses of D-pathway of bovine heart cytochrome c oxidase suggest that the pathway does not transfer the pumping protons2012

    • Author(s)
      Ryohta Aminaka, Mai Itoh, Kunitoshi Shimokata, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      17th European Bioenergetics Conference
    • Place of Presentation
      Freiberg, Germany
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Characterization by mutagenesis analysis of putative proton transfer pathway, D-pathway of bovine heart cytochrome c oxidase2012

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第50回日本生物物理学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] ウシ心筋チトクロムc 酸化酵素のプロトン輸送経路の変異体解析2011

    • Author(s)
      網中良太、下方国稔、伊藤真衣、片山幸江、月原冨武、吉川信也、島田秀夫
    • Organizer
      第37回日本生体エネルギー研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Development of a Paracoccus denitorificans cell-free protein synthesis system2011

    • Author(s)
      Yukie Katayama, Mai Itoh, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第49回日本生物物理学会
    • Place of Presentation
      姫路
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Diversity in proton pumping mechanism of the terminal oxidases2011

    • Author(s)
      Hideo Shimada, Shinya Yoshikawa
    • Organizer
      生物物理学会
    • Place of Presentation
      兵庫県立大学姫路書写キャンパス(兵庫県)(招待講演)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis analysis of proton transport pathway suggested by X-ray structure of bovine heart cytochrome c oxidase2011

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第49回日本生物物理学会
    • Place of Presentation
      姫路 (一般発表と招待講演)
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Diversity in proton pumping mechanisms of the terminal oxidases, in symposium " Structural Features and Molecular Evolution of Bioenergetic Enzymes2011

    • Author(s)
      Hideo Shimada, and Shinya Yoshikawa
    • Organizer
      第49回日本生物物理学会
    • Place of Presentation
      姫路 (招待講演)
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] The integrity of the bovine heart NADH-ubiquinone oxidoreductase responsible for the quality of the 2D crystals.2010

    • Author(s)
      Satoru Shimada
    • Organizer
      日本生物物理学会第48回年会
    • Place of Presentation
      東北大学(仙台)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22247012
  • [Presentation] Mutagenesis studies on the functional mechanism of cytochrome c oxidase and cytochrome P450cam2010

    • Author(s)
      Hideo Shimada
    • Organizer
      第48回日本生物物理学会
    • Place of Presentation
      仙台 (招待講演)
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis studies on D-pathway function of bovine heart cytochrome c oxidase2010

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      16th European Bioenergetics Conference
    • Place of Presentation
      Warsaw Poland
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Proton pumping pathway of bovine heart cytochrome c oxidase2010

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Ito, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第48回日本生物物理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis studies on the functional mechanism of cytochrome c oxidase and cytochrome P450cam2010

    • Author(s)
      Hideo Shimada
    • Organizer
      第48回日本生物物理学会
    • Place of Presentation
      東北大学、川内キャンパス、仙台市(宮城県)
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Characterization of histidine-tagged cytochrome P450cam and its synthesis in a cell-free system2010

    • Author(s)
      Yukie Katayama, Miyuki Yoshiya, Keisuke Sakurai and Hideo Shimada
    • Organizer
      第48回日本生物物理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] The functional analysis of hydrogen bond network in bovine heart cytochrome c oxidase by mutagenesism2009

    • Author(s)
      Ryohta Aminaka, Kunitoshi Shimokata, Mai Itoh, Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第47回日本生物物理学会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] HeLa細胞でのミトコンドリアから核への情報伝達2009

    • Author(s)
      島田秀夫, 他
    • Organizer
      生体エネルギー研究会第35回討論会
    • Place of Presentation
      旭川医科大学
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-20051023
  • [Presentation] チトクロム酸化酵素の部位特異的同位体標識2009

    • Author(s)
      島田秀夫, 他
    • Organizer
      第47回日本生物物理学会
    • Place of Presentation
      アスティー徳島
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Synthesis of Paracoccus denitrificans cytochrome c oxidase in the E. coli cell-free system2009

    • Author(s)
      Yukie Katayama, Tomitake Tsukihara, Shinya Yoshikawa, and Hideo Shimada
    • Organizer
      第47回日本生物物理学会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis studies on the functional roles of possible proton transfer pathways in bovine heart cytochrome c oxidase2009

    • Author(s)
      島田秀夫, et al
    • Organizer
      14^<th> Internatinal conference on Biological Inorganic Chemistry
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] チトクロム酸化酵素の部位特異的同位体標識2009

    • Author(s)
      島田秀夫, 他
    • Organizer
      第47回日本生物物理学会
    • Place of Presentation
      アスティー徳島
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-20051023
  • [Presentation] ウシ(サブユニットI)/ヒト雑種チトクロムc酸化酵素のHeLa細胞発現系2009

    • Author(s)
      島田秀夫
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20051023
  • [Presentation] HeLa細胞でのミトコンドリアから核への情報伝達2009

    • Author(s)
      島田秀夫, 他
    • Organizer
      生体エネルギー研究会第35回討論会
    • Place of Presentation
      旭川医科大学
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] ウシ(サブユニットI)/ヒト雑種チトクロムc酸化酵素のHeLa細胞発現系2009

    • Author(s)
      島田秀夫
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] 細菌チトクロムc 酸化酵素の変異体解析が支持するプロトンポンプ経路の変異に対応したウシ心筋酵素部位の変異体解析2009

    • Author(s)
      網中良太、下方国稔、伊藤真衣、片山幸江、月原冨武、吉川信也、島田秀夫
    • Organizer
      生体エネルギー研究会第35回討論会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis Studies on the Functional Roles of Possible Proton Transfer Pathways in Bovine Heart Cytochrome c Oxidase2009

    • Author(s)
      Hideo Shimada, Kunitoshi Shimokata, Ryohta Aminaka, Yukie Katayama, Kazumasa Muramoto, Tomitake Tsukihara, Shinya Yoshikawa
    • Organizer
      14th International Conference in Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan (Invited)
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] ウシ心筋チトクロムc 酸化酵素のX 線構造が示唆する水形成用プロトン輸送系の機能解析2009

    • Author(s)
      網中良太、下方国稔、伊藤真衣、片山幸江、月原冨武、吉川信也、島田秀夫
    • Organizer
      第6回「生体超分子の構造形成と機能制御の原子機構」公開シンポジュウム大阪
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] ウシ(サブユニットI)/ヒト雑種チトクロムc 酸化酵素のHeLa 細胞発現系:ミトコンドリアにおけるミトコンドリアおよび核由来タンパク質の発現誘導2009

    • Author(s)
      下方国稔、網中良太、末松 誠、月原富武、吉川信也、島田秀夫
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] Mutagenesis studies on the functional roles of possible proton transfer pathways in bovine heart cytochrome c oxidase2009

    • Author(s)
      Shimada, Hideo, et al
    • Organizer
      14^<th> Internatinal conference on Biological Inorganic Chemistry
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-20051023
  • [Presentation] Site-directed isotope labeling of cytochrome c oxidase2009

    • Author(s)
      Hideo Shimada, Yukie Katayama, Takashi Ogura, Tomitake Tsukihara, Shinya Yoshikawa
    • Organizer
      第47回日本生物物理学会
    • Place of Presentation
      徳島 (招待講演)
    • Data Source
      KAKENHI-PROJECT-21370073
  • [Presentation] ウシ心筋NADH―ユビキノン酸化還元酵素の2次元結晶化

    • Author(s)
      島田悟
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-22247012
  • 1.  EGAWA Tsuyoshi (10232935)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  NAGANO Shingo (60286440)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HIROSE Tadaaki (60051405)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KIMATA Yoko (60255429)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  ISHIMURA Yuzuru (40025599)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MIKI Hideho (90229667)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MUKAI Kuniaki (80229913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  HAYASHI Takashi (20222226)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  堀 洋 (20127294)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  菱木 貴子 (10338022)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KATAYAMA Yukie (70464998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 12.  YOSHIKAWA Shinya (40068119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OGURA Takashi (70183770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIYAZAWA Otsuo (60247252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MURAMOTO Kazumasa (50305679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAMIYA Katsumasa (60436243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  WATANABE Yoshihito (10201245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OZAKI Shin-ichi (40280581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TORAYA Tetsuo (50135597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HAYASHI Hideyuki (00183913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HAYASHI Katsuyuki (20133134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TORAYA Tetsuo (70026318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HIROTSU Ken (10047269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  FUJII Hiroshi (80228957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HISAEDA Yoshio (70150498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TANAKA Torahiko (90171785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  IIZUKA Tetsutaro (30029475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  SHIRO Yoshitsugu (70183051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  MAKINO Ryu (40101026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  西野 武士 (40094312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  谷口 寿章 (10257636)
    # of Collaborated Projects: 1 results
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  • 32.  津山 伸吾 (00094508)
    # of Collaborated Projects: 1 results
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  • 33.  小林 一雄 (30116032)
    # of Collaborated Projects: 1 results
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  • 34.  野口 正人 (10124611)
    # of Collaborated Projects: 1 results
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  • 35.  今井 嘉郎 (60029949)
    # of Collaborated Projects: 1 results
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  • 36.  堀池 喜八郎 (80089870)
    # of Collaborated Projects: 1 results
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  • 37.  三浦 洌 (70093466)
    # of Collaborated Projects: 1 results
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  • 38.  高橋 勝緒 (30087580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  AMINAKA Ryohta
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 40.  TAKAHASHI Katsuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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