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Asai Naoya  浅井 直也

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… Alternative Names

ASAI Naoya  浅井 直也

浅井 直也  アサイ ナオヤ

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Researcher Number 80273233
Other IDs
Affiliation (Current) 2025: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 藤田医科大学, 医学部, 教授
2018 – 2019: 名古屋大学, 医学部, 招へい教員
2010 – 2018: 名古屋大学, 医学系研究科, 准教授
2015: 名古屋大学, 大学院医学系研究科, 准教授
2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 准教授 … More
2008 – 2011: 名古屋大学, 大学院・医学系研究科, 准教授
2007: 名古屋大学, 医学系研究科, 准教授
2007: Nagoya University, 大学院・医学系研究科, COE特任准教授
2006: 名古屋大学, 大学院医学系研究科, COE特任助教授
1997 – 1998: 名古屋大学, 医学部, 講師
1996 – 1997: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Basic Section 49030:Experimental pathology-related / Experimental pathology / Biological Sciences / Cell biology
Except Principal Investigator
Experimental pathology / Basic Section 49030:Experimental pathology-related / Tumor biology / Hygiene / Experimental pathology / Biological Sciences
Keywords
Principal Investigator
細胞運動 / 遺伝子改変動物 / 蛋白リン酸化 / 遺伝子改変マウス / アクチン結合蛋白 / Ret / 疾患モデルマウス / 細胞移動 / 神経発生 / 血管新生 … More / PTBドメイン / SH2ドメイン / Shc / GDNF / MEN2型 / チロシンキナーゼ / 浸潤 / 膵がん / ミトコンドリア機能 / 3D培養 / 癌幹細胞 / 癌モデル / ヒトiPS細胞 / 細胞動態 / 膵癌 / 強皮症 / 臓器線維化症 / 線維化症 / 間葉系幹細胞 / 癌関連線維芽細胞 / 臓器線維症 / 神経 / 癌 / 線維化 / 中枢神経の発生 / タンパク質リン酸化 / GEF活性 / チロシンリン酸化 / 脳神経発生 / 行動解析 / 蛋白リン酸 / 海馬神経 / BDNF/TekB/Akiシグナル / シナプス可塑性 / 記憶障害 / 網膜 / 血管発生 / 血管-神経ワイヤリング / 神経新生 / 遺伝子変異マウス / 血管・神経相互作用 / 転写因子 / 下垂体発生 / アポトーシス / 依存性受容体 / Retチロシンキナーゼ / Aktキナーゼ / 細胞骨格 / VEGF / ノックアウトマウス / Girdin / ジスルフィド結合 / 褐色細胞腫 / FMTC / MEN2A型,2B型 / Rho / P13-kinase / Paxillin / FAK / PI30Cas / Crk / Neurturin / Hirschsprung病 / Shcアダプター蛋白 / MEN2B / MEN2A / retプロトオンコジーン … More
Except Principal Investigator
Girdin / 細胞運動 / 遺伝子改変マウス / ノックアウトマウス / 神経新生 / Akt / CAF / シグナル伝達 / TIMP / MMP / Wntシグナル / Daple / がんの浸潤、転移 / リン酸化 / がんの進展 / 神経発生 / 嗅球 / 海馬 / 血管新生 / RET / 低分子化合物 / BMPシグナル / Gremlin1 / ISLR / リシルオキシダーゼ / 肺がん / がんの線維化 / Am80 / 尿路上皮がん / 免疫チェックポイント阻害剤 / AM80 / 泌尿器がん / 非小細胞肺がん / 大腸がん / 膵がん / Meflin / がん関連線維芽細胞 / エンドサイトシース / cancer progression / Hydrocephalus / PEHO syndrome / Tuft細胞 / チロシンリン酸化抗体 / mTORC1活性 / アミノ酸シグナル / 4F2hcとの / がん / ダイニン / 水頭症 / 繊毛運動 / アクチン細胞骨格 / がん細胞の集団移動 / 精神神経疾患 / がん遺伝子 / システム生物学 / 癌 / メラニン / 内耳性難聴 / ラセン神経節 / 先天性難聴 / 加齢性難聴 / 感音性難聴 / 騒音性難聴 / 感音難聴 / 騒音 / 分子標的療法 / 色素細胞 / 難聴 / 労働衛生学 / 環境ストレス / 睡眠てんかん / てんかんビデオモニタリング / 実験病理学 / モデルマウス / 感覚辺縁系過剰結合 / 全般化発作 / 動物モデル / 海馬硬化 / 側頭葉てんかん / malignant melanoma / medullary thyroid carcinoma / RET gene / metastasis / transgenic mouse / MMP-9 / ret遺伝子 / チロシンキナーゼ / MEN2A / 甲状腺髄様癌 / 悪性黒色腫 / RET遺伝子 / 癌転移 / トランスジェニックマウス / エンドサイトーシス / Rac / Disheveled / focal adhesion / チロシンリン酸化 / ノックインマウス / ノックアウトマス / 細胞極性 / Par-3 / 病的血管新生 / 癌関連線維芽細胞 / 乳癌 / 長期記憶 / シナプス形成 / NMDA受容体 / 血管内膜肥厚 / 網膜血管新生 / がん微小環境 / Aktキナーゼ / VEGF / AKT / 内膜損傷モデル / 血管内皮 / ERストレス / GRP78 / Gipie / がん細胞の浸潤 / アクチン結合蛋白 / 酸化ストレス / Zn SOD / Cu / 筋萎縮性側索硬化症 / GDNF Less
  • Research Projects

    (22 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (42 People)
  •  膵癌の発生と進展におけるGirdin遺伝子の役割:癌幹細胞の新生と癌浸潤への関与Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Fujita Health University
  •  Functional Analysis of Meflin in Cancer Fibrosis and Research for Development of Novel Therapy

    • Principal Investigator
      Takahashi Masahide
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Fujita Health University
  •  Roles of Girdin in organ fibrosis and cancer associated fibrosisPrincipal Investigator

    • Principal Investigator
      Asai Naoya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Fujita Health University
      Nagoya University
  •  Roles of Girdin in neural and cancer cell migration along vesselsPrincipal Investigator

    • Principal Investigator
      Asai Naoya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Girdinファミリー分子の機能と精神神経疾患・がんの病態形成における役割

    • Principal Investigator
      高橋 雅英
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Functional analysis of Girdin family proteins in psyco-neurological disease and cancer

    • Principal Investigator
      Takahashi Masahide
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Investigation of pathogenesis of mesial temporal epilepsy using monogenic mouse model

    • Principal Investigator
      Asai Masato
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Roles of TTF-1/NKX2-1 lineage-survival oncogene in lung adenocarcinoma

    • Principal Investigator
      Takahashi Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Nagoya University
  •  Roles of Girdin in synaptic plasticity and memoryPrincipal Investigator

    • Principal Investigator
      ASAI Naoya
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  新規アクチン結合蛋白ガーディンの変異マウスを用いた、血管と神経の相互作用の解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Molecular mechanisms of postnatal angiogenesis and neurogenesis

    • Principal Investigator
      TAKAHASHI Masahide
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Roles of Girdin phosphorylation by Akt kinase in human diseases

    • Principal Investigator
      TAKAHASHI Masahide
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Study of Ret proapoptotic activity and its relation with human diseasesPrincipal Investigator

    • Principal Investigator
      ASAI Naoya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Physiological functions of the Akt substrate Girdin and its family proteins and their roles in pathogenesis

    • Principal Investigator
      TAKAHASHI Masahide (TAKAHASHI Mashide)
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Development of preventive therapy of no-se-induced hearing loss through clarifying its mechanism

    • Principal Investigator
      KATO MASASHI (KATO Masashi)
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Chubu University
  •  遺伝子改変マウスを用いた、新規アクチン結合蛋白とそのファミリーの解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Nagoya University
  •  Ret蛋白の変異によって生じる多様な臨床病態の解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  家族性筋萎縮性側索硬化症型変異を持つCu/ZnSODのGDNF/Ret系への影響

    • Principal Investigator
      岩下 寿秀
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  Ret蛋白の変異によって生じる多様な臨床病態の解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  変異型Ret蛋白による細胞癌化に特異的なシグナル伝達の解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  Analysis of molecular mechanisms of cancer metastasis using transgenic mice

    • Principal Investigator
      TAKAHASHI Masahide
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University
  •  retプロトオンコジーンの変異による細胞癌化機構の解析Principal Investigator

    • Principal Investigator
      浅井 直也
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Patent

  • [Journal Article] Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas2024

    • Author(s)
      Ando R, Shiraki Y, Miyai Y, Shimizu H, Furuhashi K, Minatoguchi S, Kato K, Kato A, Iida T, Mizutani Y, Ito K, Asai N, Mii S, Esaki N, Takahashi M, Enomoto A.
    • Journal Title

      J Pathol

      Volume: 262 Issue: 1 Pages: 61-75

    • DOI

      10.1002/path.6211

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K18390, KAKENHI-PROJECT-21K07941, KAKENHI-PROJECT-22K07000, KAKENHI-PROJECT-22K07010, KAKENHI-PROJECT-23K06491, KAKENHI-PROJECT-23K24110
  • [Journal Article] Effect of eribulin on epithelial-mesenchymal transition plasticity in metastatic breast cancer: An exploratory, prospective study2023

    • Author(s)
      Hayashi T, Kobayashi N, Ushida K, Asai N, Nakano S, Fujii K, Ando T, Utsumi T.
    • Journal Title

      Genes Cells.

      Volume: 28(5) Issue: 5 Pages: 364-373

    • DOI

      10.1111/gtc.13019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07010
  • [Journal Article] Significance of expression of CD109 in osteosarcoma and its involvement in tumor progression via BMP signaling2023

    • Author(s)
      Mori N, Esaki N, Shimoyama Y, Shiraki Y, Asai N, Sakai T, Nishida Y, Takahashi M, Enomoto A, Mii S.
    • Journal Title

      Pathol Res Pract.

      Volume: 245 Pages: 154443-154443

    • DOI

      10.1016/j.prp.2023.154443

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07010, KAKENHI-PROJECT-22K18390, KAKENHI-PROJECT-21K19561, KAKENHI-PROJECT-22K07000, KAKENHI-PROJECT-23K24110
  • [Journal Article] A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts2022

    • Author(s)
      Minatoguchi S, Saito S, Furuhashi K, Sawa Y, Okazaki M, Shimamura Y, Kaihan AB, Hashimoto Y, Yasuda Y, Hara A, Mizutani Y, Ando R, Kato N, Ishimoto T, Tsuboi N, Esaki N, Matsuyama M, Shiraki Y, Kobayashi H, Asai N, Enomoto A, Maruyama S.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 5389-5389

    • DOI

      10.1038/s41598-022-09331-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07010, KAKENHI-PROJECT-20K08589, KAKENHI-PROJECT-20H03575
  • [Journal Article] Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells2022

    • Author(s)
      Hisamori Shigeo、Mukohyama Junko、Koul Sanjay、Hayashi Takanori、Rothenberg Michael Evan、Maeda Masao、Isobe Taichi、Valencia Salazar Luis Enrique、Qian Xin、Johnston Darius Michael、Qian Dalong、Lao Kaiqin、Asai Naoya、Kakeji Yoshihiro、Gennarino Vincenzo Alessandro、Sahoo Debashis、Dalerba Piero、Shimono Yohei
    • Journal Title

      Journal of Gastroenterology

      Volume: Online ahead of print Issue: 6 Pages: 407-422

    • DOI

      10.1007/s00535-022-01865-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09076, KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-22K07010, KAKENHI-PROJECT-20K17687, KAKENHI-PROJECT-23K21387
  • [Journal Article] Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade2022

    • Author(s)
      Miyai Yuki、Sugiyama Daisuke、Hase Tetsunari、Asai Naoya、Taki Tetsuro、Nishida Kazuki、Fukui Takayuki、Chen-Yoshikawa Toyofumi Fengshi、Kobayashi Hiroki、Mii Shinji、Shiraki Yukihiro、Hasegawa Yoshinori、Nishikawa Hiroyoshi、Ando Yuichi、Takahashi Masahide、Enomoto Atsushi
    • Journal Title

      Life Science Alliance

      Volume: 5 Issue: 6 Pages: e202101230-e202101230

    • DOI

      10.26508/lsa.202101230

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K22807, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03528, KAKENHI-PROJECT-21K20821, KAKENHI-PROJECT-22K07000, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-20H03467, KAKENHI-PROJECT-19K07503
  • [Journal Article] Antitumor effect of polyphyllin D on liver metastases of neuroblastoma2022

    • Author(s)
      Kondo Y, Watanabe S, Naoe A, Takeuchi T, Niimi A, Suzuki M, Asai N, Okada S, Tsuchiya T, Murayama M, Yasui T, Inoue M, Suzuki T.
    • Journal Title

      Pediatr Surg Int.

      Volume: 38(8) Pages: 2022-2022

    • DOI

      10.1007/s00383-022-05146-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07010
  • [Journal Article] The balance of stromal BMP signaling mediated by GREM1 and ISLR drives colorectal carcinogenesis.2021

    • Author(s)
      Kobayashi H, Gieniec KA, Wright JA, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Suzuki N, Lannagan TR, Ng JQ, Hara A, Shiraki Y, Mii S (14番目/36人中), ..., Enomoto A, Takahashi M, Worthley DL, Woods SL.
    • Journal Title

      Gastroenterology.

      Volume: 160 Issue: 4 Pages: 1224-1239

    • DOI

      10.1053/j.gastro.2020.11.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07503, KAKENHI-PROJECT-18H02638, KAKENHI-PROJECT-18K07042, KAKENHI-PROJECT-20H03467
  • [Journal Article] Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin/Islr in Cancer Fibrosis2021

    • Author(s)
      Takahashi M, Kobayashi H, Mizutani Y, Hara A, Iida T, Miyai Y, Asai N, Enomoto A.
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 749924-749924

    • DOI

      10.3389/fcell.2021.749924

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03467
  • [Journal Article] Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity2021

    • Author(s)
      Hara A, Kato K, Ishihara T, Kobayashi H, Asai N, Mii S, Shiraki Y, Miyai Y, Ando R, Mizutani Y, Iida T, Takefuji M, Murohara T, Takahashi M, Enomoto A.
    • Journal Title

      Genes Cells

      Volume: - Issue: 7 Pages: 495-512

    • DOI

      10.1111/gtc.12855

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07042, KAKENHI-PROJECT-20H03467, KAKENHI-PROJECT-19K07503
  • [Journal Article] Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.2019

    • Author(s)
      Mizutani Y, Kobayashi H, Iida T, Asai N, Masamune A, Hara A, Yamaguchi J, Wang T, Woods SL, Worthley D, Shimamura T, Fujishiro M, Hirooka Y, Enomoto A, Takahashi M. et al.
    • Journal Title

      Cancer Res.

      Volume: 79 Issue: 20 Pages: 5367-5381

    • DOI

      10.1158/0008-5472.can-19-0454

    • NAID

      120006786261

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07042, KAKENHI-PROJECT-19K07503, KAKENHI-PROJECT-18K15116, KAKENHI-PROJECT-19K17429, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-18H02638, KAKENHI-PROJECT-16H02457
  • [Journal Article] Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin in Cardiac Tissue Repair and the Development of Diastolic Dysfunction.2019

    • Author(s)
      Hara A, Kobayashi H, Asai N, Saito S, Higuchi T, Kato K, Okumura T, Bando YK, Takefuji M, Mizutani Y, Miyai Y, Saito S, Maruyama S, Maeda K, Ouchi N, Nagasaka A, Miyata T, Mii S, Kioka N, Worthley DL, Murohara T, Takahashi M, Enomoto A.
    • Journal Title

      Circ. Res.

      Volume: 125 Issue: 4 Pages: 414-430

    • DOI

      10.1161/circresaha.119.314806

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07042, KAKENHI-PROJECT-18K19541, KAKENHI-PROJECT-19K22279, KAKENHI-PROJECT-17H04175, KAKENHI-PROJECT-18H02638, KAKENHI-PROJECT-19H03651, KAKENHI-PROJECT-17K09696, KAKENHI-PROJECT-18H02805, KAKENHI-PROJECT-15K21774, KAKENHI-PROJECT-16H02457
  • [Journal Article] Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex2018

    • Author(s)
      Liang Weng , Yi-Peng Han, Atsushi Enomoto, Yasuyuki Kitaura, Shushi Nagamori, Yoshikatsu Kanai, Naoya Asai, Jian An, Maki Takagishi, Masato Asai, Shinji Mii, Takashi Masuko, Yoshiharu Shimomura, Masahide Takahashi.
    • Journal Title

      PLoS Biology

      Volume: 16 Issue: 3 Pages: e2005090-e2005090

    • DOI

      10.1371/journal.pbio.2005090

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15593, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-17H03817, KAKENHI-PROJECT-17H04190, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-17K17791, KAKENHI-PROJECT-18H02638, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-17H04065
  • [Journal Article] Use of Anti-phospho-girdin Antibodies to Visualize Intestinal Tuft Cells in Free-Floating Mouse Jejunum Cryosections.2018

    • Author(s)
      Mizutani Y, Kuga D, Iida M, Ushida K, Takagi T, Tokita Y, Takahashi M, Asai M.
    • Journal Title

      Journal of visualized experiments: JoVE

      Volume: 21 Issue: 133 Pages: 133-133

    • DOI

      10.3791/57475

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10152, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-17H04065
  • [Journal Article] Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization2018

    • Author(s)
      Wang Xiaoze、Enomoto Atsushi、Weng Liang、Mizutani Yasuyuki、Abudureyimu Shaniya、Esaki Nobutoshi、Tsuyuki Yuta、Chen Chen、Mii Shinji、Asai Naoya、Haga Hisashi、Ishida Sumire、Yokota Kenji、Akiyama Masashi、Takahashi Masahide
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 11 Pages: 3643-3656

    • DOI

      10.1111/cas.13795

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07150, KAKENHI-PROJECT-26221304
  • [Journal Article] Significance of perivascular tumour cells defined by CD109 expression in progression of glioma2017

    • Author(s)
      Shiraki Yukihiro、Mii Shinji、Enomoto Atsushi、Momota Hiroyuki、Han Yi-Peng、Kato Takuya、Ushida Kaori、Kato Akira、Asai Naoya、Murakumo Yoshiki、Aoki Kosuke、Suzuki Hiromichi、Ohka Fumiharu、Wakabayashi Toshihiko、Todo Tomoki、Ogawa Seishi、Natsume Atsushi、Takahashi Masahide
    • Journal Title

      The Journal of Pathology

      Volume: 243 Issue: 4 Pages: 468-480

    • DOI

      10.1002/path.4981

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08731, KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26253073, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-15H02822
  • [Journal Article] Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells.2017

    • Author(s)
      Han YP, Enomoto A, Shiraki Y, Wang SQ, Wang X, Toyokuni S, Asai N, Ushida K, Ara H, Ohka F, Wakabayashi T, Ma J, Natsume A, Takahashi M.
    • Journal Title

      Neuro Oncol

      Volume: 19 Pages: 636-647

    • DOI

      10.1093/neuonc/now237

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-26221304
  • [Journal Article] Tyrosine Phosphorylation of an Actin-Binding Protein Girdin Specifically Marks Tuft Cells in Human and Mouse Gut.2017

    • Author(s)
      Kuga D, Ushida K, Mii S, Enomoto A, Asai N, Nagino M, Takahashi M, Asai M.
    • Journal Title

      J Histochem Cytochem.

      Volume: 65(6) Issue: 6 Pages: 347-366

    • DOI

      10.1369/0022155417702586

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-17H04065
  • [Journal Article] Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus2017

    • Author(s)
      Maki Takagishi, Masato Sawada, Shinya Ohata, Naoya Asai, Atsushi Enomoto, Kunihiko Takahashi, Liang Weng, Kaori Ushida, Hosne Ara, Shigeyuki Matsui, Kozo Kaibuchi,3Kazunobu Sawamoto, and Masahide Takahashi.
    • Journal Title

      Cell Reports

      Volume: 20 Issue: 4 Pages: 960-972

    • DOI

      10.1016/j.celrep.2017.06.089

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15593, KAKENHI-PUBLICLY-17H05512, KAKENHI-PUBLICLY-17H05561, KAKENHI-PUBLICLY-17H05693, KAKENHI-PUBLICLY-17H05750, KAKENHI-PROJECT-17H01392, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-17K17791, KAKENHI-PROJECT-26221304
  • [Journal Article] CCDC88A mutations cause PEHO-like syndrome in humans and mouse.2016

    • Author(s)
      Nahorski MS, Asai M, Wakeling E, Parker A, Asai N, Canham N, Holder SE, Chen YC, Dyer J, Brady AF, Takahashi M, Woods CG.
    • Journal Title

      Brain.

      Volume: 139 Issue: 4 Pages: 1036-1044

    • DOI

      10.1093/brain/aww014

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-26221304
  • [Journal Article] Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells.2016

    • Author(s)
      Han YP, Enomoto A, Shiraki Y, Wang SQ, Wang X, Toyokuni S, Asai N, Ushida K, Ara H, Ohka F, Wakabayashi T, Ma J, Natsume A, Takahashi M.
    • Journal Title

      Neuro Oncol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08399
  • [Journal Article] Suppression of skin tumorigenesis in CD109-deficient mice.2016

    • Author(s)
      Sunagawa M, Mii S, Enomoto A, Kato T, Murakumo Y, Shiraki Y, Asai N, Asai M, Nagino M, Takahashi M.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 50 Pages: 82836-82850

    • DOI

      10.18632/oncotarget.12653

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02822, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104
  • [Journal Article] Collective invasion of cancer: Perspectives from pathology and development2016

    • Author(s)
      Wang X, Enomoto A, Asai N, Kato T, Takahashi M
    • Journal Title

      Pathol Int

      Volume: 66 Issue: 4 Pages: 183-192

    • DOI

      10.1111/pin.12391

    • NAID

      120005893271

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-26221304
  • [Journal Article] Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells2016

    • Author(s)
      Maeda K, Enomoto A, Hara A, Asai N, Kobayashi T, Horinouchi A, Maruyama S, Ishikawa Y, Nishiyama T, Kiyoi H, Kato T, Ando K, Weng L, Mii S, Asai M, Mizutani Y, Watanabe O, Hirooka Y, Goto H, Takahashi M
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 22288-22288

    • DOI

      10.1038/srep22288

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26506009, KAKENHI-PROJECT-15K21061, KAKENHI-PLANNED-24120007, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-25860293
  • [Journal Article] Akt-Girdin as oncotarget.2015

    • Author(s)
      Takahashi M, Asai N, Enomoto A.
    • Journal Title

      Oncoscience.

      Volume: 2(10) Pages: 811-812

    • Data Source
      KAKENHI-PROJECT-15K08399
  • [Journal Article] Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury2015

    • Author(s)
      Nakano T, Kotani T, Mano Y, Tsuda H, Imai K, Ushida T, Li H, Miki R, Sumigama S, Sato Y, Iwase A, Hirakawa A, Asai M, Toyokuni S, Kikkawa F.
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 57 Issue: 3 Pages: 178-182

    • DOI

      10.3164/jcbn.15-90

    • NAID

      130005106454

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461630, KAKENHI-PROJECT-26462484, KAKENHI-PROJECT-25460493
  • [Journal Article] New endoplasmic reticulum stress regulator, gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.2015

    • Author(s)
      Noda T, Maeda K, Hayano S, Asai N, Enomoto A, Takahashi M, Murohara T
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 35 Issue: 5 Pages: 1246-1253

    • DOI

      10.1161/atvbaha.114.304923

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-26293184, KAKENHI-PROJECT-26221304
  • [Journal Article] Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin2015

    • Author(s)
      Aya Muramatsu, Atsushi Enomoto, Takuya Kato, Liang Weng, Keisuke Kuroda, Naoya Asai, Masato Asai, Shinji Mii, Masahide Takahashia
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 463 Issue: 4 Pages: 999-1005

    • DOI

      10.1016/j.bbrc.2015.06.049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-15K21061, KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-26640074, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26221304
  • [Journal Article] Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction.2015

    • Author(s)
      Hayano S, Takefuji M, Maeda K, Noda T, Ichimiya H, Kobayashi K, Enomoto A, Asai N, Takahashi M, Murohara T.
    • Journal Title

      J Mol Cell Cardiol.

      Volume: 88 Pages: 55-63

    • DOI

      10.1016/j.yjmcc.2015.09.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-26293184, KAKENHI-PROJECT-26221304
  • [Journal Article] Akt-Girdin as oncotarget2015

    • Author(s)
      Masahide Takahashi, Naoya Asai, Atsushi Enomoto
    • Journal Title

      Oncoscience

      Volume: 2 Issue: 10 Pages: 811-812

    • DOI

      10.18632/oncoscience.233

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26221304
  • [Journal Article] Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration2015

    • Author(s)
      Kenji Omori, Masato Asai, Daisuke Kuga, Kaori Ushida, Tetsuya Izuchi, Shinji Mii, Atsushi Enomoto, Naoya Asai, Masato Nagino, Masahide Takahashi
    • Journal Title

      Biochem. Biopys. Res. Commun.

      Volume: 458 Issue: 4 Pages: 934-940

    • DOI

      10.1016/j.bbrc.2015.02.065

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
  • [Journal Article] A role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis2015

    • Author(s)
      Hosne Ara, Maki Takagishi, Atsushi Enomoto, Masato Asai, Kaori Ushida, Naoya Asai, Yoshie Shimoyama, Kozo Kaibuchi, Yasuhiro Kodera and Masahide Takahashi.
    • Journal Title

      Cancer Science

      Volume: 107 Issue: 2 Pages: 133-139

    • DOI

      10.1111/cas.12848

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-13J40134, KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-26221304
  • [Journal Article] Akt-girdin signaling in cancer-associated fibroblasts contributes to tumor progression2015

    • Author(s)
      Yumiko Yamamura, Naoya Asai, Atsushi Enomoto, Takuya Kato, Shinji Mii, Yuji Kondo, Kaori Ushida, Kaoru Niimi, Nobuyuki Tsunoda, Masato Nagino, Shu Ichihara, Koichi Furukawa, Kengo Maeda, Toyoaki Murohara, Masahide Takahashi
    • Journal Title

      Cancer Research

      Volume: 75 Issue: 5 Pages: 813-823

    • DOI

      10.1158/0008-5472.can-14-1317

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-15K15080, KAKENHI-PROJECT-26221304
  • [Journal Article] Role of Girdin in intimal hyperplasia in vein grafts and efficacy of atelocollagen-mediated application of siRNA for vein failure2014

    • Author(s)
      Miyachi, H., Mii, S., Enomoto, A., Murakumo, Y., Kato, T., Asai, N., Komori, K. and Takahashi, M.
    • Journal Title

      J. Vasc. Surg.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells.2014

    • Author(s)
      Niimi K, Murakumo Y, Watanabe N, Kato T, Mii S, Enomoto A, Asai M, Asai N, Yamamoto E, Kajiyama H, Shibata K, Kikkawa F, Takahashi M.
    • Journal Title

      Cancer Sci.

      Volume: 105 Issue: 5 Pages: 545-52

    • DOI

      10.1111/cas.12390

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24650618, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-25460493
  • [Journal Article] Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.2014

    • Author(s)
      Liang Weng, Atsushi Enomoto, Hiroshi Miyoshi, Kiyofumi Takahashi, Naoya Asai, Nobuhiro Morone, Ping Jiang, Jian An, Takuya Kato, Keisuke Kuroda, Takashi Watanabe, Masato Asai, Maki Ishida-Takagishi, Yoshiki Murakumo, Hideki Nakashima, Kozo Kaibuchi and Masahide Takahashi.
    • Journal Title

      EMBO Journal.

      Volume: 33 Issue: 18 Pages: 2098-2112

    • DOI

      10.15252/embj.201488289

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J40134, KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25430118, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-26253024, KAKENHI-PROJECT-26286027, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
  • [Journal Article] Girdin phosphorylation is crucial for synaptic plasticity and memory: A potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor2014

    • Author(s)
      Tsuyoshi Nakai, Taku Nagai, Motoki Tanaka, Norimichi Itoh, Naoya Asai, Atsushi Enomoto, Masato Asai, Shinnnosuke Yamada, Ali Bin Saifullah, Masahiro Sokabe, Masahide Takahashi, Kiyofumi Yamada
    • Journal Title

      The Journal of Neuroscience

      Volume: 34 Issue: 45 Pages: 14995-15008

    • DOI

      10.1523/jneurosci.2228-14.2014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
  • [Journal Article] Role of Girdin in intimal hyperplasia in vein grafts and efficacy of atelocollagen-mediated application of siRNA for vein failure2014

    • Author(s)
      Hiroki Miyachi, Shinji Mii, Atsushi Enomoto, Yoshiki Murakumo, Takuya Kato, Naoya Asai, Kimihiro Komori, Masahide Takahashi
    • Journal Title

      Journal of Vascular Surgery

      Volume: 60 Issue: 2 Pages: 479-489

    • DOI

      10.1016/j.jvs.2013.06.080

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24591873, KAKENHI-PROJECT-24659586, KAKENHI-PROJECT-25293295, KAKENHI-PROJECT-25462160, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26253024
  • [Journal Article] Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA2014

    • Author(s)
      Haruko Ota, Takao Hikita, Masato Sawada, Tomoki Nishioka, Mami Matsumoto, Masayuki Komura, Akihisa Ohno, Yukiyo Kamiya, Takuya Miyamoto, Naoya Asai, Atsushi Enomoto, Masahide Takahashi, Kozo Kaibuchi, Kazuya Sobue, Kazunobu Sawamoto
    • Journal Title

      Nature Communications

      Volume: 5 Issue: 1 Pages: 4532-4532

    • DOI

      10.1038/ncomms5532

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PLANNED-22122004, KAKENHI-PROJECT-26221304
  • [Journal Article] Detection of a Soluble Form of CD109 in Serum of CD109 Transgenic and Tumor Xenografted Mice.2014

    • Author(s)
      Sakakura H, Murakumo Y, Mii S, Hagiwara S, Kato T, Asai M, Hoshino A, Yamamoto N, Sobue S, Ichihara M, Ueda M, Takahashi M.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: e83385-e83385

    • DOI

      10.1371/journal.pone.0083385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-25460493
  • [Journal Article] TRIM27/MRTF-B-Dependent Integrin β1 Expression Defines Leading Cells in Cancer Cell Collectives.2014

    • Author(s)
      Takuya Kato, Atsushi Enomoto, Takashi Watanabe, Hisashi Haga, Sumire Ishida, Yuji Kondo, Koichi Furukawa, Takeshi Urano, Shinji Mii, Liang Weng, Maki Ishida-Takagishi, Masato Asai, Naoya Asai, Kozo Kaibuchi, Yoshiki Murakumo, Masahide Takahashi.
    • Journal Title

      Cell reports.

      Volume: 7 Issue: 4 Pages: 1156-1167

    • DOI

      10.1016/j.celrep.2014.03.068

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J40134, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26640074, KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-25460493
  • [Journal Article] The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.2013

    • Author(s)
      Watanabe, N., Mii, S., Asai, N., Asai, M., Niimi, K., Ushida, K., Kato, T., Enomoto, A., Ishii, H., Takahashi, M., Murakumo, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Issue: 15 Pages: 10459-10471

    • DOI

      10.1074/jbc.m112.421966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-23651189, KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25134711, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-25460493
  • [Journal Article] Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain2013

    • Author(s)
      Ota, H., Hikita, T., Nishioka, T., Matsumoto, M., Ito, J., Asai, N., Enomoto, A., Takahashi, M., Kaibuchi, K., Sobue, K. and Sawamoto, K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 442 Pages: 16-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.2013

    • Author(s)
      Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, Majzoub JA.
    • Journal Title

      Science

      Volume: 341 Issue: 6143 Pages: 275-278

    • DOI

      10.1126/science.1233000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Journal Article] Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina2013

    • Author(s)
      Ito, T., Komeima, K., Yasuma, T., Enomoto, A., Asai, N., Iwase, S., Takahashi, M. and Terasaki, H.
    • Journal Title

      Am. J. Pathol.

      Volume: 182 Pages: 586-596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina2013

    • Author(s)
      Takanori Ito, Keiichi Komeima, Tetsuhiro Yasuma, Atsushi Enomoto, Naoya Asai, Masato Asai, Sayoko Iwase, Masahide Takahashi, Hiroko Terasaki
    • Journal Title

      American Journal of Pathology

      Volume: 182 Issue: 2 Pages: 586-596

    • DOI

      10.1016/j.ajpath.2012.10.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-23390401, KAKENHI-PROJECT-24390095, KAKENHI-PUBLICLY-23111511, KAKENHI-PUBLICLY-23122508
  • [Journal Article] Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain2013

    • Author(s)
      Haruko Ota, Takao Hikita, Tomoki Nishioka, Mami Matsumoto, Jun Ito, Naoya Asai, Atsushi Enomoto, Masahide Takahashi, Kozo Kaibuchi, Kazuya Sobue, Kazunobu Sawamoto
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 442 Issue: 1-2 Pages: 16-21

    • DOI

      10.1016/j.bbrc.2013.10.126

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-23791722, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25113513
  • [Journal Article] The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility2012

    • Author(s)
      Ishida-Takagishi, M., Enomoto, A., Asai, N., Ushida, K., Watanabe, T., Hashimoto, T., Kato, T., Weng, L., Matsumoto, S., Asai, M., Murakumo, Y., Kaibuchi, K., Kikuchi, A. and Takahashi, M.
    • Journal Title

      Nature Commun.

      Volume: May 29 3 Pages: 859-859

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Similar Phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage2012

    • Author(s)
      Asai M., Asai, N., Murata, A., Yokota, H., Ohmori, K., Mii, S., Enomoto, A., Murakumo, Y. and Takahashi, M.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 426 Pages: 533-538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Involvement of Girdin in the determination of cell polarity during cell migration2012

    • Author(s)
      Ohara, K., Enomoto, A., Kato, T., Hashimoto, T., Isotani-Sakakibara, M., Asai, N., Ishida,-Takagishi, M., Weng, L., Nakayama, M., Watanabe, T., Kato, K., Kaibuchi, K., Murakumo, Y., Hirooka, Y., Goto, H. and Takahashi M.
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage2012

    • Author(s)
      Masato Asai
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 426 Issue: 4 Pages: 533-538

    • DOI

      10.1016/j.bbrc.2012.08.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24590479, KAKENHI-PLANNED-22117005, KAKENHI-PUBLICLY-23122508
  • [Journal Article] Partial impairment of c-Ret at tyrosine1062 accelerates age-related hearing loss in mice2012

    • Author(s)
      Ohgami N, Ida-Eto M, Sakashita N, Sone M, Nakashima T, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M.
    • Journal Title

      Neurobiol Aging

      Volume: 33(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] Partial impairment of c-Ret at tyrosine 1062 accelerates age-related hearing loss in mice.2011

    • Author(s)
      Ohgami N, Ida-Etoh M, SakashitaN, Sone M, Nakashima N, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M
    • Journal Title

      Neurobiol Aging (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Loss of Sprouty2 partially rescues renal hypoplasia and stomach hypoganglionosis but not intestinal aganglionosis in Ret Y1062F mutant mice.2011

    • Author(s)
      Miyamoto, R., Jijiwa, M., Asai, M., Kawai, K., Ishida-Takagishi, M., Mii, S., Asai, N., Enomoto, A., Murakumo, Y., Yoshimura, A., Takahashi M.
    • Journal Title

      Dev.Biol. 349

      Pages: 160-168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain2011

    • Author(s)
      Wang, Y., Kaneko, N., Asai, N., Enomoto, A., Isotani-Sakakibara, M., Kato, T., Asai, M., Murakumo, Y., Ota, H., Hikita, T., Namba, T., Kuroda, K., Kaibuchi, K., Ming, G., Song, H., Sawamoto, K. and Takahashi, M.
    • Journal Title

      J. Neurosci.

      Volume: 31 Pages: 8109-8122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] Loss of Sprouty2 partially rescues renalhy poplasia and stomach hypoganglionosisbut not intestinal aganglionosis in RetY1062F mutant mice2011

    • Author(s)
      Miyamoto R, Jijiwa M, Asai M, Kawai K, Ishida-Takagishi M, Mii S, Asai N, Enomoto A, Murakumo Y, Yoshimura A, Takahashi M.
    • Journal Title

      Dev Biol

      Volume: 349(2) Pages: 160-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury2011

    • Author(s)
      Miyake, H., Maeda, K., Asai, N., Shibata, R., Ichimiya, H., Isotani-Sakakibara, M., Yamamura, Y., Kato, K., Enomoto, A., Takahashi, M. and Murohara, T.
    • Journal Title

      Circ. Res.

      Volume: 108 Pages: 1170-1179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Journal Article] c-Ret-mediated hearing loss in mice with Hirschsprung disease2010

    • Author(s)
      Ohgami N, Ida-Eto M, Shimotake T, Sakashita N, Sone M, Nakashima T, TabuchiK, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 107(29) Pages: 13051-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] c-Ret-mediated hearing loss in mice with Hirschsprung disease.2010

    • Author(s)
      Ohgami N, Ida M, Shimotake T, Sakashita N, Sone M, Nakashima T, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M
    • Journal Title

      Proc Natl Acad Sci USA 107(29)

      Pages: 13051-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] c-Ret-mediated hearing loss in mice with Hirschsprung disease.2010

    • Author(s)
      Ohgami N, Ida M, Shimotake T, Sakashita N, Sone M, Nakashima T, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue C, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 13051-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Girding for migratory cues: Role of the Akt substrate Girdin in cancer progression and angiogenesis.2010

    • Author(s)
      Weng, L., Enomoto, A., Ishida-Takagishi, M.,Asai, N., Takahashi M.
    • Journal Title

      Cancer Sci. 101

      Pages: 836-842

    • NAID

      10026590367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells2010

    • Author(s)
      Kurotsuchi A, Murakumo Y, Jijiwa M, Kurokawa K, Itoh Y, Kodama Y, Kato T, Enomoto A, Asai N, Terasaki H, Takahashi M.
    • Journal Title

      Cancer Sci

      Volume: 101(5) Pages: 1147-55

    • NAID

      10026592015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] Roles of Disrupted-in-Schizophrenia 1-interacting protein Girdin in postnatal development of the dentate gyrus.2009

    • Author(s)
      Enomoto, A., Asai, N., Namba, T., Wang, Y., Kato, T., Tanaka, M., Tatsumi, H., Taya, S., Tsuboi, D., Kuroda, K., Kaneko, N., Sawamoto, K., Miyamoto, R., Jijiwa, M., Murakumo, Y., Sokabe, M., Seki, T., Kaibuchi, K., Takahashi M.
    • Journal Title

      Neuron 63

      Pages: 774-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Ret-dependent cell rearrangements in the Wolffian duct pithelium initiate ureteric bud morphogenesis2009

    • Author(s)
      Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F
    • Journal Title

      Dev Cell 17(2)

      Pages: 199-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis2009

    • Author(s)
      Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F.
    • Journal Title

      Dev Cell

      Volume: 17(2) Pages: 199-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.2009

    • Author(s)
      Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F
    • Journal Title

      Dev Cell 17(2)

      Pages: 199-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Roles of Disrupted-in-Schizophrenia 1-interacting protein Girdin in postnatal development of the dentate gyrus2009

    • Author(s)
      Enomoto, A., Asai, N., Namba, T., Wang, Y., Kato, T., Tanaka, M., Tatsumi, H., Taya, S., Tsuboi, D., Kuroda, K., Kaneko, N., Sawamoto, K., Miyamoto, R., Jijiwa, M., Murakumo, Y., Sokabe, M., Seki, T., Kaibuchi, K., Takahashi, M.
    • Journal Title

      Neuron 63

      Pages: 774-787

    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis2009

    • Author(s)
      Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, D' Agati V, Costantini F.
    • Journal Title

      Nat Genet

      Volume: 41(12) Pages: 1295-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] RET遺伝子の機能と多発性内分泌腫瘍症2型2009

    • Author(s)
      浅井直也、高橋雅英
    • Journal Title

      ホルモンと臨床

      Volume: 57(3) Pages: 39-45

    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] RET遺伝子の機能と多発性内分泌腫瘍症2型2009

    • Author(s)
      浅井直也、高橋雅英
    • Journal Title

      ホルモンと臨床 57(3)

      Pages: 39-45

    • Data Source
      KAKENHI-PROJECT-21590436
  • [Journal Article] An actin-binding protein Girdin regulates the motility of breast cancer cells2008

    • Author(s)
      Jiang, P., Enomoto, A., Jijiwa, M., Kato, T., Hasegawa, T., Ishida, M., Sato, T., Asai, N., Murakumo, Y., Takahashi, M.
    • Journal Title

      Cancer Res. 68

      Pages: 1310-1318

    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] An actin-binding protein Girdin regulates the motility of breast cancer cells.2008

    • Author(s)
      Jiang, P., Enomoto, A., Jijiwa, M., Kato, T., Hasegawa, T., Ishida, M., Sato, T., Asai, N., Murakumo, Y., Takahashi M.
    • Journal Title

      Cancer Res. 68

      Pages: 1310-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.2008

    • Author(s)
      Kitamura, T., Asai, N., Enomoto, A., Maeda, K., Kato, T., Ishida, M., Jiang, P., Watanabe, T., Usukura, J., Kondo, T., Costantini, F., Murohara, T., Takahashi M.
    • Journal Title

      Nature Cell Biol. 10

      Pages: 329-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin2008

    • Author(s)
      Kitamura, T., Asai, N., Enomoto, A., Maeda, K., Kato, T., Ishida, M., Jiang, P., Watanabe, T., Usukura, J., Kondo, T., Costantini, F., Murohara, T., Takahashi, M.
    • Journal Title

      Nature Cell Biol. 10

      Pages: 329-337

    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.2006

    • Author(s)
      Naoya Asai
    • Journal Title

      Development 133(22)

      Pages: 4507-4516

    • Data Source
      KAKENHI-PROJECT-18657060
  • [Journal Article] RET receptor signaling : dysfunction in thyroid cancer and Hirschsprung's disease.2006

    • Author(s)
      Naoya Asai
    • Journal Title

      Pathology International 56(4)

      Pages: 164-172

    • NAID

      10018196115

    • Data Source
      KAKENHI-PROJECT-18657060
  • [Journal Article] Girding for migratory cues : Role of the Akt substrate Girdin in cancer progression and angiogenesis

    • Author(s)
      Weng, L., Enomoto, A., Ishida-Takagishi, M., Asai, N., Takahashi, M.
    • Journal Title

      Cancer Sci. (in press)

    • NAID

      10026590367

    • Data Source
      KAKENHI-PROJECT-19209013
  • [Journal Article] Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cell.

    • Author(s)
      .Matsushita, E., Asai, N., Enomoto, A., Kawamoto, Y., Kato, T., Mii, S., Maeda, K., Shibata, R., Hattori, S., Hagikura, M., Takahashi, k., Sokabe, M., Murakumo, Y., Murohara, T., Takahashi M.
    • Journal Title

      Mol.Biol.Cell. in press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Patent] ノックアウトマウス、内側側頭葉てんかんを抑制する物質のスクリーニング方法、及び内側側頭葉てんかんを抑制する手法の選択方法2015

    • Inventor(s)
      浅井真人、髙橋雅英、浅井直也、榎本篤、内山孝蔵
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-10-13
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Patent] ノックアウトマウス、内側側頭葉てんかんを抑制する物質のスクリーニング方法、及び内側側頭葉てんかんを抑制する手法の選択方法2014

    • Inventor(s)
      浅井真人、高橋雅英、浅井直也、榎本篤、内山孝蔵
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-10-14
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Patent] ノックアウトマウス、内側側頭葉てんかんを抑制する物質のスクリーニング方法、及び内側側頭葉てんかんを抑制する手法の選択方法2014

    • Inventor(s)
      浅井真人、髙橋雅英、浅井直也、榎本篤、内山孝蔵
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-10-14
    • Acquisition Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Patent] 難聴モデル動物及びその用途2009

    • Inventor(s)
      加藤昌志, 大神信孝, 高橋雅英, 浅井直也, 時々輪真由美
    • Industrial Property Rights Holder
      中部大学、名古屋大学
    • Industrial Property Number
      2009-053481
    • Filing Date
      2009-03-06
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Patent] 難聴モデル動物及びその用途2009

    • Inventor(s)
      加藤昌志, 大神信孝, 高橋雅英, 浅井直也, 時々輪真由美
    • Industrial Property Rights Holder
      中部大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2009-03-06
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Patent] 難聴モデル動物及びその用途2009

    • Inventor(s)
      加藤昌志、大神信孝、高橋雅英、浅井直也、時々輪真由美
    • Industrial Property Rights Holder
      中部大学、名古屋大学
    • Industrial Property Number
      2009-053481
    • Filing Date
      2009-03-06
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Presentation] 創薬を目的とした高品質の側頭葉てんかんマウスモデル2016

    • Author(s)
      浅井真人
    • Organizer
      中部地区医療・バイオ系シーズ発表会
    • Place of Presentation
      名古屋市中小企業振興会館吹上ホール(愛知県名古屋市)
    • Year and Date
      2016-02-04
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] Meflin is a specific marker for mesenchymal stem cells (MSCs) whose expression is regulatedby substrate stiffness.2016

    • Author(s)
      Atsushi Enomoto, Naoya Asai, Takeshi Kobayashi, Nobuhisa Nakamura. Masahide Takahashi
    • Organizer
      ASCB Annual Meeting 2016 (San Francisco, USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221304
  • [Presentation] がんの進展におけるAkt-girdinシグナル伝達系の役割2016

    • Author(s)
      高橋雅英、榎本篤、浅井直也
    • Organizer
      第75回日本癌学会学術総会(横浜、神奈川)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221304
  • [Presentation] Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin2015

    • Author(s)
      Liang Weng, Atsushi Enomoto, Naoya Asai, Takuya Kato, Takashi Watanabe, Kozo Kaibuchi, Masahide Takahashi
    • Organizer
      The 6th EMBO meeting
    • Place of Presentation
      The International Convention Centre (Birmingham, UK)
    • Year and Date
      2015-09-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221304
  • [Presentation] 哺乳類消化管タフト細胞とアノイキスに陥った吸収上皮の同一性2015

    • Author(s)
      陸大輔 浅井真人 浅井直也 榎本篤 梛野正人 高橋雅英
    • Organizer
      第104回 日本病理学会総会
    • Place of Presentation
      愛知県名古屋市 名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] 遺伝子Xのノックアウトマウス 理想的な内側側頭葉てんかんモデルマウス2015

    • Author(s)
      浅井真人
    • Organizer
      DSANJ疾患別商談会(中枢神経系疾患領域)
    • Place of Presentation
      大阪産業創造館(大阪府大阪市)
    • Year and Date
      2015-08-28
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] メラノコルチン2受容体付属タンパク2(MRAP2)の機能喪失は哺乳類の肥満と関連する2015

    • Author(s)
      浅井真人
    • Organizer
      第49回日本小児内分泌学会学術集会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] Mrap2遺伝子変異と肥満2014

    • Author(s)
      浅井真人
    • Organizer
      第41回 日本神経内分泌学会学術集会
    • Place of Presentation
      東京都千代田区 都道府県会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] 癌関連線維芽細胞においてAktシグナル下流にあるGirdinがリン酸化されることにより腫瘍増大を引き起こす2014

    • Author(s)
      山村由美子、浅井直也、榎本篤、加藤琢哉、三井伸二、近藤裕史、前田健吾、室原豊明、高橋雅英
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26221304
  • [Presentation] Roles of the Akt substrate Girdin in cancer progression and angiogenesis2014

    • Author(s)
      Takahashi, M., Enomoto, A. and Asai, N.
    • Organizer
      International Symposium on Nanomedicine
    • Place of Presentation
      Nagoya University Graduate School of Medicine, Nagoya
    • Data Source
      KAKENHI-PROJECT-23249020
  • [Presentation] リン酸化Girdin特異的抗体の作製とマウス脳における組織学的検討2013

    • Author(s)
      浅井真人
    • Organizer
      日本病理学会総会
    • Place of Presentation
      ロイトン札幌 札幌市
    • Year and Date
      2013-06-06
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] Phosphorylation of Girdin in Colorectal Cancer2013

    • Author(s)
      大森健治、浅井真人、榎本篤、浅井直也、梛野正人、高橋 雅英
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜 横浜市
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-25460493
  • [Presentation] 新規先天性難聴遺伝子の解析2011

    • Author(s)
      大神信孝、下竹孝志、時々輪真由美、浅井直也、高橋雅英、加藤昌志
    • Organizer
      第81回日本衛生学会総会
    • Place of Presentation
      東京都(一般演題)
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Presentation] 腸管神経におけるGDNF/Retシグナルの役割界2011

    • Author(s)
      浅井直也、時々輪真由美、高橋雅英
    • Organizer
      第88回日本生理学界・第116回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] 腸管神経におけるGDNF/Retシグナルの役割2011

    • Author(s)
      浅井直也、時事輪真由美、高橋雅英
    • Organizer
      第88回日本生理学界・第116回日本解剖学会総会・全国学術集会
    • Place of Presentation
      神奈川県、横浜
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] Regulation of angiogenesis and neointima formation by the Akt substrate Girdin2010

    • Author(s)
      高橋雅英、北村倫也、三宅裕史、前田健吾、榎本篤、浅井直也、室原豊明
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-19209013
  • [Presentation] Functional analysis of RET tyrosinekinase receptor as a dependence receptor2009

    • Author(s)
      Takahashi M, Asai N, Costantini F
    • Organizer
      2nd International symposium, Development of the enteric nervous system
    • Place of Presentation
      London, UK
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] Retチロシンキナーゼにより形成される細胞内断片の転写制御因子としての作用2009

    • Author(s)
      浅井直也、高橋雅英
    • Organizer
      第68回、日本癌学会学術総会
    • Place of Presentation
      神奈川県、横浜
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] Retチロシンキナーゼにより形成される細胞内断片の転写制御因子としての作用2009

    • Author(s)
      浅井直也、高橋雅英
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      神奈川県、横浜
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] 依存性受容体としてのRETチロシンキナーゼの機能と腸管神経の発生2009

    • Author(s)
      高橋雅英、浅井直也
    • Organizer
      第62回日本自律神経学会総会
    • Place of Presentation
      和歌山県、和歌山市
    • Data Source
      KAKENHI-PROJECT-21590436
  • [Presentation] Analysis of the Ret knock-in mice with D707N mutation.2007

    • Author(s)
      浅井直也
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18657060
  • [Presentation] 癌関連線維芽細胞においてAktシグナルの下流にあるGirdinがリン酸化されることにより腫瘍増大を引き起こす

    • Author(s)
      山村由美子、浅井直也、榎本篤、加藤琢哉、三井伸二、近藤裕史、前田健吾、室原豊明、高橋雅英
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26253024
  • [Presentation] 腫瘍微小環境におけるAkt結合蛋白Girdinの関与の検討

    • Author(s)
      山村由美子、浅井直也、榎本篤、加藤琢哉、前田健吾、室原豊明、高橋雅英
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-26253024
  • [Presentation] Akt signaling in cancer-associated fibroblasts contributes ot tumor progression via Girdin phosphorylation

    • Author(s)
      山村由美子、浅井直也、榎本篤、加藤琢哉、三井伸二、近藤裕史、前田健吾、室原豊明、高橋雅英
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PLANNED-22117005
  • [Presentation] 腫瘍微小環境におけるAkt結合蛋白Girdinの関与の検討

    • Author(s)
      山村由美子、浅井直也、榎本篤、加藤琢哉、前田健吾、室原豊明、高橋雅英
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県、広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PLANNED-22117005
  • 1.  TAKAHASHI Masahide (40183446)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 37 results
  • 2.  ENOMOTO Atsushi (20432255)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 41 results
  • 3.  IWASHITA Toshihide (00283432)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MURAKUMO Yoshiki (40324438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  NAGAI Taku (10377426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAKASHIMA Izumi (40022826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Asai Masato (70543536)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 8.  KATO MASASHI (10281073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 9.  OHGAMI Nobutaka (80424919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  Takahashi Takashi (50231395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MIYANO Satoru (50128104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YANAGISAWA Kiyoshi (20372112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  川本 善之 (10410664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  山ノ下 理 (50424924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  後藤 友二 (70362522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HIDESHI Ishii
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  SHI Lei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  MOMOTA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  MAEDA Kengo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  TOMOKI Nishioka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  TAKAO Keizo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  SATO Noriko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  KOBAYASHI Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  高岸 麻紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 25.  吉川 史隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  梶山 広明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  三井 伸二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  黒田 啓介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  久森 重夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  宮井 雄基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  飯田 真智子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  貝淵 弘三
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  高尾 昌樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  高尾 英正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  高橋 良輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  伊佐 正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  祖父江 元
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  青木 茂樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  太田 順
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  饗場 篤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  高橋 淑子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  芳賀 永
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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