Furuyama Kazumichi 古山和道

… Alternative Names

FURUYAMA Kazumichi 古山和道

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Researcher Number	80280874
Other IDs
External Links
Affiliation (Current)	2025: 岩手医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 岩手医科大学, 医学部, 教授 2013: 岩手医科大学, 医学部, 教授 2011 – 2012: 東北大学, 医学(系)研究科(研究院), 准教授 2008 – 2010: Tohoku University, 大学院・医学系研究科, 准教授 2007: 東北大学, 大学院・医学系・研究科, 准教授 … More 2006: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 2004 – 2005: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2003 – 2004: 東北大学, 大学院・医学系研究科, 助手 1999 – 2001: 東北大学, 大学院・医学系研究科, 助手 1996 – 1998: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 49010:Pathological biochemistry-related / General medical chemistry / Pathological medical chemistry Except Principal Investigator Biological Sciences / General medical chemistry / General medical chemistry / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 54010:Hematology and medical oncology-related / Basic Section 43030:Functional biochemistry-related … More / Hematology / Hematology / Functional biochemistry / Pathological medical chemistry / Pathological medical chemistry Less
Keywords	Principal Investigator アミノレブリン酸合成酵素 / RNA interference / 遺伝性鉄芽球性貧血 / ヘム / aminolevulinate synthase / スクシニルCoA合成酵素 / 質量分析 / 5-アミノレブリン酸合成酵素 / ミトコンドリア / 赤芽球 … More / 翻訳後修飾 / 鉄芽球性貧血 / apoptosis / 鉄欠乏性貧血モデル細胞 / 鉄芽球性貧血モデル細胞 / 環状鉄芽球 / モデル細胞 / ゲノム編集 / 疾患モデル細胞 / ferroptosis / 細胞死 / 蛋白質 / 酵素 / ATP依存性タンパク質分解酵素 / ATP依存性マトリクスプロテアーゼ / LONP1 / CLPXP / ATP依存性プロテアーゼ / マトリクス / heme oxygenase / heme / アミルブリン酸合成酵素 / ヘムオキシゲナーゼ / hereditary sideroblastic anemia / succinyl CoA synthethase / RNA干渉法 / Hereditary Sideroblastic Anemia / Succinyl CoA synthethase / 5-aminolevulinate synthase / split hybrid system / スクシニルCoAシンターゼ / スクシニルCoA酵素 / 翻訳後調節 / ５－アミノレブリン酸合成酵素 / SUMO / 分子病態学 … More Except Principal Investigator ヘム / ヘム合成 / 転写因子 / ヘムオキシゲナーゼ / ミトコンドリア / 鉄代謝 / 赤血球分化 / Bach2 / Bach1 / MafK / GATA-1 / NF-E2 / transcription factor / M-TAT細胞 / GATA-2 / MITF / 低酸素 / 肺動脈 / 酸素センサー / ストレス / T細胞 / 細胞死 / 発ガン / 転写制御 / 5-アミノレブリン酸合成酵素 / 脂肪酸β酸化 / 代謝シフト / エネルギー代謝 / フェロトーシス / ヘム合成系 / プロテアーゼ / ヘム生合成経路 / タンパク質分解 / 鉄芽球性貧血 / erythrocyte / ventilatory response / oxygen sensor / heme oxygenase / 赤血球 / 換気応答 / 小眼球症関連転写因子 / T cell / apoptosis / cancer development / Transcriptional regulation / erythroid differentiation / iron metabolism / heme / ALAS2 / 赤血球型δ-アミノレブリン酸合成酵素 / 合成酵素 / 赤血球型δ-アミノレブリン酸 / X染色体連鎖性鉄芽球性貧血 / 赤血球型б-アミノレブリン酸合成酵素 / 赤血球型δアミノレブリン酸合成酵素 / coproporphyrinogen oxidase / 5-aminolevulinate synthase / heme regulatory motif / メロンボポエチン / Bach因子 / p45 / コプロポルフィリノーゲンオキシダーゼ / ヘム調節モチーフ / transgenic mouse / hematopoiesis / leukemia cells / promoter / enhancer / 病型診断 / 造血前駆細胞 / GATA因子 / MLP / トロンボポエチン / 造血細胞 / プロモーター / 白血病 / 血球分化 / GATA-2因子 / GATA-1因子 / 遺伝子導入マウス / 転写調節 / 白血病細胞 / 選択的プロモーター / 造血細胞特異的エンハンサー / 回避行動 / 網膜色素上皮細胞 / ストレス応答 / 生体防御 / L1エレメント / メラニン / 網膜色素上皮 / イオンチャネル / 換気血流不均等 / 小細胞肺がん / シグナル伝達 / 癌 / 気道神経上皮小体 / 換気・血流比 / 発現制御 / 酸素 / がん / ヘパリン / 表面抗原 / 細胞株 / ヒスチジン脱炭酸酵素 / ノックアウトマウス / 分化 / 肥満細胞 / ヒスタミン / 組織特異性 / ハーダー氏腺 / ハム / 神経細胞 / 胎盤-胎児系 Less

肝細胞におけるCLPXによる代謝シフトのメカニズムおよびその生理的意義の解明
- Principal Investigator
  
  鈴木亘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Iwate Medical University
Analyses of the mechanism for the cell death of ring sideroblastsPrincipal Investigator
- Principal Investigator
  
  Furuyama Kazumichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Iwate Medical University
Analysis of mitochondrial iron accumulation mechanism on sideroblastic anemia model cells
- Principal Investigator
  
  Kaneko Kiriko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Iwate Medical University
Analysis of heme-dependent degradation mechanisms of ALAS1, mitochondrial heme synthesis enzyme
- Principal Investigator
  
  Kubota Yoshiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Iwate Medical University
The protein quality control in mitochondrial matrix by ATP-dependent proteasesPrincipal Investigator
- Principal Investigator
  
  Furuyama Kazumichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Iwate Medical University
The analysis of mechanism for mitochondrial iron accumulation on sideroblastic anemia model cells
- Principal Investigator
  
  Kaneko Kiriko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Iwate Medical University
Homeostasis of retinal pigment epithelium essential for survival of photorecptor cells
- Principal Investigator
  
  SHIBAHARA Shigeki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Regulatory mechanisms for heme biosynthesis in response to the change of regulatory heme pool.Principal Investigator
- Principal Investigator
  
  FURUYAMA Kazumichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Iwate Medical University
  Tohoku University
Post-translational modification of erythroid-specific 5-aminolevulinate synthase and its' role in erythroid differentiation.Principal Investigator
- Principal Investigator
  
  FURUYAMA Kazumichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
肺がんの進展に関与する肺循環血流の制御機構の解明
- Principal Investigator
  
  柴原茂樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
肺がんの発生と進展に関与する肺特異的低酸素応答の分子機構の解明
- Principal Investigator
  
  柴原茂樹
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Multiple mechanisms for the regulation of heme biosynthesis and catabolism.Principal Investigator
- Principal Investigator
  
  FURUYAMA Kazumichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
肺特異的低酸素応答と換気・血流比維持機構の解明
- Principal Investigator
  
  柴原茂樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Molecular basis for hypoxic sensing and regulation of ventilatory responses
- Principal Investigator
  
  SHIBAHARA Shigeki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
腫瘍の形成と維持を規定する低酸素応答の分子基盤
- Principal Investigator
  
  SHIBAHARA Shigeki
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
The disruption of protein-protein interaction in mitochondria results in sideroblastic anemia.Principal Investigator
- Principal Investigator
  
  FURUYAMA Kazumichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
ヒスタミンによる肥満細胞分化制御機構
- Principal Investigator
  
  大津浩
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写因子Nrf3の大腸癌とapoptosis誘導における機能解析
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Functional analyses of the CNC transcription factor Nrf3 in colon cancer and T cell development
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Research for the relationship of hereditary sideroblastic anemia with enzyme complex formation in mitochondriaPrincipal Investigator
- Principal Investigator
  
  FURUYAMA Kazumichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Identification of the causative gene for inherited sideroblastic anemia and analysis of sideroblastis induced in vitro
- Principal Investigator
  
  HARIGAE Hideo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tohoku University
生命の適応戦略:ヘムの機能の考案
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
  Tohoku University
Regulation of erythroid differentiation by trnscription factors and heme
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Analysis of the expression profile of lineage-specific transcription factors in leukemia cells
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University

[Book] Handbook of Porphyrin Science, Volume 27 p 1-392013
- Author(s)
  Kazumichi Furuyama and Masayuki Yamamoto
- Total Pages
  39
- Publisher
  World Scientific Publishing Co. Pte. Ltd.
- Data Source
  KAKENHI-PROJECT-23590353
[Book] Handbook of porphyrin science(volume 27)
- Author(s)
  Furuyama K, Yamamoto M(Ferreira G.C. edited)
- Publisher
  World Scientific Publishing Co.Ltd
- Data Source
  KAKENHI-PROJECT-23590353
[Journal Article] Erythroid-specific 5-aminolevulinate synthase is stabilized by HSPA9 in mitochondrial matrix2023
- Author(s)
  Costantine Chasama Kamata, Yoshiko Kubota, Kazumichi Furuyama
- Journal Title
  
  Journal of Iwate Medical Assiociation
  
  Volume: 75 Issue: 2 Pages: 49
- DOI
  10.24750/iwateishi.75.2_49
- ISSN
  0021-3284, 2434-0855
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06874
[Journal Article] <i>In vitro</i> analyses for the diagnosis of congenital sideroblastic anemia2023
- Author(s)
  古山和道、Kamata Costantine Chasama
- Journal Title
  
  Journal of Iwate Medical Assiociation
  
  Volume: 75 Issue: 1 Pages: 1-9
- DOI
  10.24750/iwateishi.75.1_1
- ISSN
  0021-3284, 2434-0855
- Year and Date
  2023-04-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06874
[Journal Article] CLPX regulates mitochondrial fatty acid β-oxidation in liver cells2023
- Author(s)
  Suzuki Ko、Kubota Yoshiko、Kaneko Kiriko、Kamata Costantine Chasama、Furuyama Kazumichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 10 Pages: 105210-105210
- DOI
  10.1016/j.jbc.2023.105210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06874, KAKENHI-PROJECT-21K08375
[Journal Article] Mass spectrometric analysis of erythroid specific 5-aminolevulinate synthase protein complex2023
- Author(s)
  鈴木　亘, Costantine Chasama Kamata, 古山和道
- Journal Title
  
  Journal of Iwate Medical Assiociation
  
  Volume: 75 Issue: 2 Pages: 69-79
- DOI
  10.24750/iwateishi.75.2_69
- ISSN
  0021-3284, 2434-0855
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06874
[Journal Article] Heme‐dependent recognition of 5‐aminolevulinate synthase by the human mitochondrial molecular chaperone ClpX2021
- Author(s)
  Nomura Kazumi、Kitagawa Yu、Aihara Marina、Ohki Yusuke、Furuyama Kazumichi、Hirokawa Takatsugu
- Journal Title
  
  FEBS Letters
  
  Volume: 595 Issue: 24 Pages: 3019-3029
- DOI
  10.1002/1873-3468.14214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06874
[Journal Article] Establishment of a cell model of X-linked sideroblastic anemia using genome editing.2018
- Author(s)
  Kaneko K, Kubota Y, Nomura K, Hayashimoto H, Chida T, Yoshino N, Wayama M, Ogasawara K, Nakamura Y, Tooyama I, Furuyama K
- Journal Title
  
  Exp Hematol
  
  Volume: 65 Pages: 57-68
- DOI
  10.1016/j.exphem.2018.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08640, KAKENHI-PROJECT-17K09910
[Journal Article] A novel heterozygous ALAS2 mutation in a female with macrocytic sideroblastic anemia resembling myelodysplastic syndrome with ring sideroblasts: a case report and literature review2017
- Author(s)
  Fujiwara T, Fukuhara N, Ichikawa S, Kobayashi M, Okitsu Y, Onishi Y, Furuyama K, Harigae H
- Journal Title
  
  Annals of Hematology
  
  Volume: 96(11) Issue: 11 Pages: 1955-1957
- DOI
  10.1007/s00277-017-3106-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-17K08640, KAKENHI-PROJECT-17K16176, KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-15K09447
[Journal Article] Iron metabolism in erythroid cells and patients with congenital sideroblastic anemia2017
- Author(s)
  Furuyama Kazumichi、Kaneko Kiriko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 107 Issue: 1 Pages: 44-54
- DOI
  10.1007/s12185-017-2368-0
- Data Source
  KAKENHI-PROJECT-17K08640, KAKENHI-PROJECT-17K09910
[Journal Article] Identification of a novel erythroid-specific enhancer for the ALAS2 gene and its loss-of-function mutation which is associated with congenital sideroblastic anemia2014
- Author(s)
  Kaneko K, Furuyama K, Fujiwara T, Kobayashi R, Ishida H, Harigae H, Shibahara S
- Journal Title
  
  Haematologica
  
  Volume: 99(2)(PubMed PMID : 23935018; PMCID : PMC3912954) Issue: 2 Pages: 252-261
- DOI
  10.3324/haematol.2013.085449
- Data Source
  KAKENHI-PROJECT-23590353
[Journal Article] Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS)2013
- Author(s)
  大場理恵、吉田健一
- Journal Title
  
  Ann Hematol
  
  Volume: 92 Issue: 1 Pages: 1-9
- DOI
  10.1007/s00277-012-1564-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23590353, KAKENHI-PROJECT-23791067
[Journal Article] Coordinated expression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 and heme oxygenase 2: evidence for a regulatory link between glycolysis and heme catabolism2012
- Author(s)
  Li B, Takeda K, Ishikawa K, Yoshizawa M, Sato M, Shibahara S, Furuyama K
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 228(1)(PMID : 22892400) Pages: 27-41
- NAID
  10031025395
- Data Source
  KAKENHI-PROJECT-23590353
[Journal Article] The carboxyl-terminal region of erythroid-specific 5-aminolevulinate synthase acts as an intrinsic modifier for its catalytic activity and protein stability.2012
- Author(s)
  Kadirvel S, Furuyama K, Harigae H, Kaneko K, Tamai Y, Ishida Y, Shibahara S.
- Journal Title
  
  Exp Hematol
  
  Volume: 40 Issue: 6 Pages: 477-486
- DOI
  10.1016/j.exphem.2012.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590353
[Journal Article] Coordinated expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 and heme oxygenase 2: evidence for a regulatory link between glycolysis and heme catabolism.2012
- Author(s)
  Li B, Takeda K, Ishikawa K, Yoshizawa M, Sato M, Shibahara S, Furuyama K.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume: 228 Pages: 27-41
- NAID
  10031025395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590353
[Journal Article] Expression of (pro)renin receptor in human erythroid cell lines and its increased protein accumulation by interferon-γ2012
- Author(s)
  Kaneko K, Nishiyama H, Ohba K, Shibasaki A, Hirose T, Totsune K, Furuyama K, Takahashi K
- Journal Title
  
  Peptides
  
  Volume: 37 Issue: 2 Pages: 285-289
- DOI
  10.1016/j.peptides.2012.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590352, KAKENHI-PROJECT-23590353, KAKENHI-PROJECT-23790242
[Journal Article] Depletion of glutamine enhances sodium butyrate-induced erythroid differentiation of K562 cells.Depletion of glutamine enhances sodium butyrate-induced erythroid differentiation of K562 cells.2012
- Author(s)
  Hiep,N. C., Kinohira, S., Furuyama, K and Taketani S
- Journal Title
  
  J. Biochem
  
  Volume: 152(6) Issue: 6 Pages: 509-519
- DOI
  10.1093/jb/mvs097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241052, KAKENHI-PROJECT-23510256, KAKENHI-PROJECT-23590353
[Journal Article] Roles of porphyrin and iron metabolisms in the δ-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin and photodamage of tumor cells2011
- Author(s)
  Yoshiko Ohgari
- Journal Title
  
  Photochemistry and Photobiology
  
  Volume: 87 Issue: 5 Pages: 1138-1145
- DOI
  10.1111/j.1751-1097.2011.00950.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380060, KAKENHI-PROJECT-22658036, KAKENHI-PROJECT-23590353
[Journal Article] Hereditary sideroblastic anemia : pathophysiology and gene mutations.2010
- Author(s)
  Harigae H, Furuyama K.
- Journal Title
  
  Int J Hematol. vol.92
  
  Pages: 425-431
- NAID
  10027673283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hypoxemia induces expression of heme oxygenase-1 and heme oxygenase-2 proteins in the mouse myocardium.2010
- Author(s)
  Han F, Takeda K, Ono M, Date F, Ishikawa K, Yokoyama S, Shinozawa Y, Furuyama K, Shibahara S.
- Journal Title
  
  J Biochem. vol.147
  
  Pages: 143-151
- NAID
  10027873503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hereditary sideroblastic anemia : pathophysiology and gene mutations.2010
- Author(s)
  Hahgae H., Furuyama K.
- Journal Title
  
  Int.J.Hematol
  
  Volume: 92 Pages: 425-431
- NAID
  10027673283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling2009
- Author(s)
  Kaneko K, Furuyama K, Aburatani H, Shibahara S
- Journal Title
  
  FEBS Journal 276
  
  Pages: 1370-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Functional expression of heme oxygenase-1 in human differentiated epidermis and its regulation by cytokines.2009
- Author(s)
  Numata I, Okuyama R, Memezawa A, Ito Y, Takeda K, Furuyama K, Shibahara S, Aiba S.
- Journal Title
  
  J Invest Dermatol. vol.129
  
  Pages: 2594-2603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling.2009
- Author(s)
  Kaneko K, Furuyama K, Aburatani H, Shibahara S.
- Journal Title
  
  FEBS J. vol.276
  
  Pages: 1370-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Induction of lipocalin-type prostaglandin D synthase in mouse heart under hypoxemia.2009
- Author(s)
  Han F, Takeda K, Ishikawa K, Ono M, Date F, Yokoyama S, Furuyama K, Shinozawa Y, Urade Y, Shibahara S.
- Journal Title
  
  Biochem Biophys Res Commun. vol.385
  
  Pages: 449-453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf2.2008
- Author(s)
  Nagai T, Kikuchi S, Ohmine K, Miyoshi T, Nakamura M, Kondo T, Furuyama K, Komatsu N, Ozawa K.
- Journal Title
  
  J Cell Biochem. vol.104
  
  Pages: 680-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway2008
- Author(s)
  Vargas PD, Furuyama K, Sassa S, Shibahara S
- Journal Title
  
  FEBS Journal 275
  
  Pages: 5947-5959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Leishmania spp. : delta-aminolevulinate-inducible neogenesis of porphyria by genetic complementation of incomplete heme biosynthesis pathway.2008
- Author(s)
  Dutta S, Furuyama K, Sassa S, Chang KP.
- Journal Title
  
  Exp Parasitol. vol.118
  
  Pages: 629-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway.2008
- Author(s)
  Vargas PD, Furuyama K, Sassa S, Shibahara S.
- Journal Title
  
  FEBS J. vol.75
  
  Pages: 5947-5959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590301
[Journal Article] Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity2006
- Author(s)
  Furuyama K.
- Journal Title
  
  Eur. J. Haematol. 76・1
  
  Pages: 33-41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity2006
- Author(s)
  Furuyama K.
- Journal Title
  
  Eur.J.Haematol. 76
  
  Pages: 33-41
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.2006
- Author(s)
  Furuyama K., et al.
- Journal Title
  
  European Journal of Haematology vol.76(1)
  
  Pages: 33-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590262
[Journal Article] Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.2006
- Author(s)
  Furuyama K.
- Journal Title
  
  European Journal of Haematology 76
  
  Pages: 33-41
- Data Source
  KAKENHI-PROJECT-17590262
[Journal Article] Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines.2006
- Author(s)
  Ding Y, Zhang Y-Z, Furuyama K, Ogawa K, Igarashi K, Shibahara S
- Journal Title
  
  FEBS J. 273 (23)
  
  Pages: 5333-5346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines : A possible strategy for the maintenance of intracellular heme level.2006
- Author(s)
  Zhang Y, Furuyama K, Kaneko K, Ding Y, Ogawa K, Yoshizawa M, Kawamura M, Takeda K, Yoshida T, Shibahara S
- Journal Title
  
  FEBS J. 273 (14)
  
  Pages: 3136-3147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.2006
- Author(s)
  Furuyama K, Harigae H, Heller T, Hamel BC, Minder EI, Shimizu T, Kuribara T, Blijlevens N, Shibahara S, Sassa S
- Journal Title
  
  Eur.J.Haematol. 76 (1)
  
  Pages: 33-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Aig452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.2006
- Author(s)
  Furuyama K.
- Journal Title
  
  European Journal of Haematology 76巻・1号
  
  Pages: 33-41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590262
[Journal Article] Dynamic changes in expression of heme oxygenases in mouse heart and liver during hypoxia.2005
- Author(s)
  Han F, Takeda K, Yokoyama S, Ueda H, Shinozawa Y, Furuyama K, Shibahara S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 338 (1)
  
  Pages: 653-659
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Expression of heme oxygenase-1 is repressed by interferon-gamma and induced by hypoxia in human retinal pigment epithelial cell.2004
- Author(s)
  R.Udono-Fujimori, K.Takahashi, K.Takeda, K.Furuyama, S.Shibahara.他
- Journal Title
  
  European Journal of Biochemistry 271
  
  Pages: 3076-3081
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Role of the heme regulatory motif in the heme-mediated inhibition of mitochondrial import of 5-aminolevulinate synthase.2004
- Author(s)
  H.Munakata, JY.Sun, K.Yoshida, T.Nakatani, E.Honda, S.Hayakawa, K.Furuyama, N.Hayashi
- Journal Title
  
  J Biochem (Tokyo) 136
  
  Pages: 233-238
- NAID
  10016201587
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Role of the heme regulatory motif in the heme-mediated inhibition of mitochondrial import of 5-aminolevulinate synthase.2004
- Author(s)
  H.Munakata, JY.Sun, K.Furuyama, N.Hayashi.他
- Journal Title
  
  Journal of Biochemistry (Tokyo) 136
  
  Pages: 233-238
- NAID
  10016201587
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2.2004
- Author(s)
  Adachi T, Ishikawa K, Hida W, Matsumoto H, Masuda T, Date F, Ogawa K, Takeda K, Furuyama K, Zhang Y, Kitamuro T, Ogawa H, Maruyama Y, Shibahara S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 320 (2)
  
  Pages: 514-522
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Expression of heme oxygenase-1 is repressed by interferon-gamma and induced by hypoxia in human retinal pigment epithelial cells.2004
- Author(s)
  R.Udono-Fujimori, K.Takahashi, K.Takeda, K.Furuyama, K.Kaneko, S.Takahashi, M.Tamai, S.Shibahara
- Journal Title
  
  Eur J Biochem. 271
  
  Pages: 3076-3081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2.2004
- Author(s)
  T.Adachi, K.Ishikawa, W.Hida, H.Matsumoto, T.Masuda, F.Date, K.Ogawa, K.Takeda, K.Furuyama, Y.Zhang, T.Kitamuro, H.Ogawa, Y.Maruyama, S.Shibahara
- Journal Title
  
  Biochem Biophys Res Commun. 320
  
  Pages: 514-522
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2.2004
- Author(s)
  T.Adachi, K.Ishikawa, K.Furuyama, S.Shibahara 他
- Journal Title
  
  Biochemistry and Biophysiology Research Communication 320
  
  Pages: 514-522
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Expression of heme oxygenase-1 is repressed by interferon-y and induced by hypoxia in human retinal pigment epithelial cells.2004
- Author(s)
  Udono-Fujimori R, Takahashi K, Takeda K, Furuyama K, Kaneko K, Takahashi S, Tamai M, Shibahara S
- Journal Title
  
  Eur.J.Biochem. 271 (14)
  
  Pages: 3076-3084
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390071
[Journal Article] Regulation of YB-1 gene expression by GATA transcription factors.2003
- Author(s)
  H.Yokoyama, H.Harigae, S.Takahashi, K.Furuyama, M.Kaku, M.Yamamoto, T.Sasaki
- Journal Title
  
  Biochem Biophys Res Commun. 303
  
  Pages: 140-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha.2003
- Author(s)
  Y.Li, K.Totsune, K.Takeda, K.Furuyama, S.Shibahara, K.Takahashi
- Journal Title
  
  Eur J Endocrinol. 149
  
  Pages: 231-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts.2003
- Author(s)
  H.Harigae, O.Nakajima, N.Suwabe, H.Yokoyama, K.Furuyama, T.Sasaki, M.Kaku, M.Yamamoto, S.Sassa
- Journal Title
  
  Blood 101
  
  Pages: 1188-1193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Bach1 functions as a hypoxia-inducible repressor for the heme oxgenase-1 gene in human cells.2003
- Author(s)
  T.Kitamuro, K.Takahashi, O.Ogawa, R.Udono-Fujimori, K.Takeda, K.Furuyama, 他
- Journal Title
  
  J Biol Chem 278
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase(ALAS2)-deficient definitive erythroblasts.2003
- Author(s)
  H.Harigae, O.Nakajima, N.Suwabe, H.Yokoyama, K.Furuyama 他
- Journal Title
  
  Blood 101
  
  Pages: 1188-1193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.2003
- Author(s)
  T.Kitamuro, K.Takahashi, K.Ogawa, R.Udono-Fujimori, K.Takeda, K.Furuyama, M.Nakayama, J.Sun, H.Fujita, W.Hida, T.Hattori, K.Shirato, K.Igarashi, S.Shibahara
- Journal Title
  
  J Biol Chem. 278
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Late-onset X-linked sideroblastic anemia following hemodialysis2003
- Author(s)
  Furuyama K, 他
- Journal Title
  
  BLOOD 101・11
  
  Pages: 4623-4624
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha.2003
- Author(s)
  Y.LI, K.Totsune, K.Takeda, K.Furuyama, 他
- Journal Title
  
  Eur J Endocrinol. 149
  
  Pages: 231-238
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Late-onset X-linked sideroblastic anemia following hemodialysis.2003
- Author(s)
  K.Furuyama, H.Harigae, C.Kinoshita, T.Shimada, K.Miyaoka, C.Kanda, Y.Maruyama, S.Shibahara, S.Sassa
- Journal Title
  
  Blood 101
  
  Pages: 4623-4624
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Journal Article] Regulation of YB-1 gene expression by GATA transcription factors.2003
- Author(s)
  H.Yokoyama, H.Harigae, S.Takahashi, K.Furuyama, 他
- Journal Title
  
  Biochem Biophys Res Commun 303
  
  Pages: 140-145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590266
[Presentation] 非特異的5-アミノレブリン酸合成酵素のヘム依存的分解反応に関わる因子の同定2021
- Author(s)
  久保田美子, 鈴木亘, 金子桐子, 古山和道
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06874
[Presentation] SLC25A38遺伝子変異細胞の樹立2021
- Author(s)
  金子桐子，久保田美子，鈴木亘，Kamata Costantine Chasama , 古山和道
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K08375
[Presentation] SLC25A38遺伝子変異細胞の樹立2021
- Author(s)
  金子桐子, 久保田美子, 鈴木亘, 古山和道
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06874
[Presentation] CLPXはタンパク質相互作用の調節を介して肝細胞におけるミトコンドリアβ酸化を制御する2021
- Author(s)
  金子桐子, 久保田美子, 鈴木亘, 古山和道
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06874
[Presentation] ミトコンドリア内ヘム依存的ALAS1分解の調節機構 Heme-dependent degradation of mitochondrial protein ALAS12019
- Author(s)
  久保田美子、金子桐子、鈴木亘、Kamata Costantine Chasama、古山和道
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06116
[Presentation] ミトコンドリア内ヘム依存的ALAS1分解の調節機構2019
- Author(s)
  久保田美子, 金子桐子, 鈴木亘, Kamata Costantine Chasama, 古山和道
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ミトコンドリア内ヘム依存的ALAS1分解の調節機構2019
- Author(s)
  久保田美子, 金子桐子, 鈴木亘, Kamata Costantine Chasama, 古山和道
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K09910
[Presentation] ヘム合成経路の律速酵素ALAS1の分解経路の抑制によるゲノム不安定性の誘導2018
- Author(s)
  久保田美子、草壁香帆里、久慈強、金子桐子、野村和美、博多修子、古山和道
- Organizer
  日本生化学会東北支部例会
- Data Source
  KAKENHI-PROJECT-18K06116
[Presentation] ALAS2変異による鉄芽球性貧血のモデル細胞構築2018
- Author(s)
  金子桐子、久保田美子、野村和美、林本遥、千田大誠、吉野直人、和山真里奈、小笠原勝利、中村幸雄、遠山育夫、古山和道
- Organizer
  第682回岩手医学会例会
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ヘム合成経路の律速酵素ALAS1の分解経路の抑制によるゲノム不安定性の誘導2018
- Author(s)
  久保田美子，草壁香帆里，久慈強，金子桐子，野村和美，博多修子，古山和道
- Organizer
  生化学会東北支部第84回例会シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] 遺伝性鉄芽球性貧血モデル細胞の樹立2018
- Author(s)
  金子桐子，林本遥，千田大誠，久保田美子，野村和美，小笠原勝利，和山真里奈，吉野直人，中村幸夫，遠山育夫，博多修子，古山和道
- Organizer
  生化学会東北支部第84回例会シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ヘム生合成経路の律速酵素ALAS1の分解経路の低下によるゲノム不安定性の誘導2017
- Author(s)
  久保田美子、久慈強、古山和道
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ヒトCLPX-CLPP複合体によるヘム結合型ALAS1の認識及び分解メカニズムの解明2017
- Author(s)
  野村和美、北川悠、大木祐亮、久保田美子、金子桐子、古山和道
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ALAS2変異による遺伝性鉄芽球性貧血のモデル細胞樹立2017
- Author(s)
  金子桐子、千田大誠、久保田美子、野村和美、古山和道
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K08640
[Presentation] ヘム（鉄-プロトポルフィリンIX）が関与する細胞内クロストーク機構2013
- Author(s)
  古山和道
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] 「ヘム鉄—プロトポルフィリンIX」が関与する細胞内クロストーク機構2013
- Author(s)
  古山和道
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Identification of the Novel Erythroid-Specific Enhancer in the First Intron of Human ALAS2 Gene;The Mutation Disrupting GATA Transcription Factor-Binding Site in the Enhancer Causes X-Linked Sideroblastic Anemia2012
- Author(s)
  Furuyama K, Kaneko K, Fujiwara T, Harigae H, Shibahara S
- Organizer
  54th Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, U.S.A
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] ヒト赤芽球特異的5-アミノレブリン酸合成酵素遺伝子における新たな赤芽球特異的エンハンサーの同定2012
- Author(s)
  古山和道、金子桐子、藤原亨、張替秀郎、柴原茂樹.
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Identification of the Novel Erythroid-Specific Enhancer in the First Intron of Human ALAS2 Gene; Tthe Mutation Disrupting GATA Transcription Factor-Binding Site in the Enhancer Causes X-Linked Sideroblastic Anemia.2012
- Author(s)
  Furuyama K, Kaneko K, Fujiwara T, Harigae H, Shibahara S.
- Organizer
  54th Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, U.S.A.
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] ヒト赤芽球特異的5−アミノレブリン酸合成酵素遺伝子における新たな赤芽球特異的エンハンサーの同定2012
- Author(s)
  古山和道, 金子桐子, 藤原亨, 張替秀郎, 柴原茂樹
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] 赤芽球特異的5−アミノレブリン酸合成酵素のカルボキシル末端は内因性抑制ドメインとして機能する2011
- Author(s)
  Senkottubelan Kadirvel,古山和道, 金子桐子, 張替秀郎, 柴原茂樹
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Expression of (pro) renin receptor in human erythroid cell lines : the effect of interferon–gamma2011
- Author(s)
  Kiriko Kaneko, Akiko Shibasaki, Hiroshi Nishiyama, Takuo Hirose, Koji Ohba, Kazuhito Totsune, Kazumichi Furuyama and Kazuhiro Takahashi
- Organizer
  第53回アメリカ血液学会
- Place of Presentation
  San Diego, U.S.A
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] haracteristics of sideroblastic anemia in japan–from the analysis of multicenter study2011
- Author(s)
  Rie Ohba, Kazumichi Furuyama, Atsushi Manaba, Etsuro Ito, Seiji Kojima, Keiya Ozawa, Hideo Harigae
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Tissue specific regulation of the enzymes in heme biosynthetic pathway under hypoxia2008
- Author(s)
  Furuyama K., et al.
- Organizer
  第8回国際ポルフィリン-ヘムシンポジウム
- Place of Presentation
  松江市
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20590301
[Presentation] 低酸素刺激によるヘモグロビン合成誘導機構2008
- Author(s)
  金子桐子、古山和道、柴原茂樹
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20590301
[Presentation] 赤芽球特異的5-アミノレブリン酸合成酵素のカルボキシル末端は内因性抑制ドメインとして機能する
- Author(s)
  Senkottubelan Kadirvel, 古山和道、金子桐子、張替秀郎、柴原茂樹
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Characteristics of sideroblastic anemia in Japan-from the analysis of multicenter study
- Author(s)
  Rie Ohba, Kazumichi Furuyama, Atsushi Manaba, Etsuro Ito, Seiji Kojima, Keiya Ozawa, Hideo Harigae
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23590353
[Presentation] Expression of (pro)renin receptor in human erythroid cell lines: the effect of interferon- gamma
- Author(s)
  Kiriko Kaneko, Akiko Shibasaki, Hiroshi Nishiyama, Takuo Hirose, Koji Ohba, Kazuhito Totsune, Kazumichi Furuyama and Kazuhiro Takahashi
- Organizer
  第53回アメリカ血液学会総会
- Place of Presentation
  サンディエゴコンベンションセンター、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-23590353

1. SHIBAHARA Shigeki (70206142)

# of Collaborated Projects: 7 results

# of Collaborated Products: 32 results
2. KANEKO Kiriko (10545784)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
3. HARIGAE Hideo (50302146)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. 鈴木亘 (90610395)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. SHIBAHARA Shigeki (00154253)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. Kubota Yoshiko (30260102)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
7. NAGAI Tadashi (40237483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KOBAYASHI Akira (50292214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HIDA Wataru (10142944)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. TAKEDA Kazuhisa (30311559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. HAYASHI Norio (00004606)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. YOSHIZAWA Miki (50221669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MINEGISHI Naoko (40271895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MUNAKATA Hiroshi (90111294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤田博美 (60142931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 大津浩 (60250742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 倉増敦朗 (90302091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 丸山芳夫 (00133942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 野村和美 (50733581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. 高橋隼一郎 (30982368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. OKITSU Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. TOTSUNE Kazuhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 佐藤亘

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
24. 吉田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 高橋和広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 武谷茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Furuyama Kazumichi 古山 和道

FURUYAMA Kazumichi 古山 和道

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Analyses of the mechanism for the cell death of ring sideroblastsPrincipal Investigator

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The protein quality control in mitochondrial matrix by ATP-dependent proteasesPrincipal Investigator

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Regulatory mechanisms for heme biosynthesis in response to the change of regulatory heme pool.Principal Investigator

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Post-translational modification of erythroid-specific 5-aminolevulinate synthase and its' role in erythroid differentiation.Principal Investigator

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Multiple mechanisms for the regulation of heme biosynthesis and catabolism.Principal Investigator

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Furuyama Kazumichi 古山和道

FURUYAMA Kazumichi 古山和道