Takahashi Takeshi 高橋武司

… Alternative Names

TAKAHASHI Takeshi 高橋武司

高橋武司タカハシタケシ

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Researcher Number	80335215
Other IDs	https://orcid.org/0000-0001-5056-0178
Affiliation (Current)	2024: 公益財団法人実中研, 実験動物基礎研究部, 部長
Affiliation (based on the past Project Information) *help	2024: 公益財団法人実中研, 実験動物基礎研究部, 部長 2020 – 2023: 公益財団法人実験動物中央研究所, 実験動物基礎研究部, 部長 2019: 公益財団法人実験動物中央研究所, 実験動物研究部, 部長 2018: 公益財団法人実験動物中央研究所, 実験動物研究部, 室長 2016: 公益財団法人実験動物中央研究所, その他部局等, 室長 … More 2016: 実験動物中央研究所, 免疫研究室, 室長 2012 – 2015: 公益財団法人実験動物中央研究所, その他部局等, 研究員 2014: 東北大学, 医学研究科, 助教 2013: 公益財団法人実験動物中央研究所, その他部局等, 室長 2011: 公益財団法人実験動物中央研究所, 実験動物研究部, 室長 2011: 公益財団法人実験動物中央研究所, 実験動物研究部, 研究員 2010: 東北大学, 医学研究科, 助教 2010: Tohoku University, 大学院・医学系研究科, 助教 2008 – 2009: Tohoku University, 大学院・医学研究科, 助教 2007 – 2008: Tohoku University Graduate School of Medicine, 大学院・医学系研究科, Assistant Professor 2002 – 2003: 京都大学, 再生医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Immunology / Laboratory animal science / Immunology Except Principal Investigator Immunology / Basic Section 53040:Nephrology-related / Laboratory animal science / Biological Sciences / Laboratory animal science
Keywords	Principal Investigator ヒト化マウス / T細胞 / 抗体医薬 / マクロファージ / 自然免疫 / Fc受容体 / アレルギー / HLA-DR / マラリア / 赤血球 … More / 受容体 / PDX / immunocheckpoint / tumor immunology / ADCC / antibody / FcR / RBC / innate immunity / immunodeficient mice / 疾患モデル / 病態モデル / クラススイッチ / 獲得免疫 / IgG / 胸腺 / NOGマウス / リンパ球 / CD25 / CD25+ / 制御性T細胞 / 免疫学的自己寛容 / 自己免疫病 … More Except Principal Investigator Foxp3 / ヒト化マウス / 近位尿細管 / 腎疾患モデル / 薬剤腎毒性評価系 / iPS細胞 / ヒト化腎臓マウス / マウスリソース開発 / 受精卵ゲノム編集 / ゲノム編集 / Cytokine / T-cell costimulatory signal / CD4 T cells / Inflammatory response / サイトカイン / T細胞補助シグナル / CD4陽性T細胞 / 炎症反応 / Immunological self-tolerance / Genetic susceptibilit / Co-stimulatory molecule / Semaphoring / Dendritic cells / Regulatory T cell / Autoimmune disease / CTLA-4 / GITR / 免疫学 / 病理学 / 単クローン抗体 / CD25 / helios / Gpr83 / GITR-L / 移植免疫 / 腫瘍免疫 / 自己免疫 / 樹状細胞 / 遺伝的疾患感受性 / セマフォリン / 教刺激分子 / 免疫自己寛容 / 制御性T細胞 / 自己免疫病 / 個別衣料 / ヒト化モデル / 免疫不全動物 / 個別化医療 / 実験動物 / 個別医療 / 実験動物学 / 免疫不全マウス / MVB / 小胞輸送 / MHC II / 抗原提示 / 細胞 Less

Generation and application of humanized kidney mice using iPS cells
- Principal Investigator
  
  長船健二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyoto University
Improvement of humanized mice through elucidation of interaction between mouse innate immune system and human cellsPrincipal Investigator
- Principal Investigator
  
  高橋武司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Central Institute for Experimental Animals
Development of highly immunodeficient mice by regulating innate immune systemsPrincipal Investigator
- Principal Investigator
  
  Takahashi Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Central Institute for Experimental Animals
Induction of human allergic responses in 2nd generation NOG micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI TAKESHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Genetic humanized Mouse production by CRISPITT
- Principal Investigator
  
  MIZUNO Seiya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of humanized mouse with functional immune systemsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Central Institute for Experimental Animals
Development of experimentation systems related to personalized medicine using humanized NOG mice
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
The analysis of immune responses in humanized NOG micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tohoku University
Regulation of APC function by STAM1/2.
- Principal Investigator
  
  MURATA Kazuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tohoku University
Regulation of effector T cells that mediate inflammatory responses
- Principal Investigator
  
  ISHII Naoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tohoku University
CD25+CD4+制御性T細胞による免疫制御機構の分子的基礎Principal Investigator
- Principal Investigator
  
  高橋武司
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Immune tolerance and regulation towards understanding and cure of autoimmune disease
- Principal Investigator
  
  SAKAGUCHI Shimon
- Project Period (FY)
  2001 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

[Book] Humanized Mice for HIV Research2015
- Author(s)
  Takahashi,T.
- Total Pages
  538
- Publisher
  横浜
- Data Source
  KAKENHI-PROJECT-22220007
[Book] Humanized Mice for HIV Reserach2014
- Author(s)
  Takahashi Takeshi
- Total Pages
  525
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26290034
[Book] Humanized Mice for HIV Research2013
- Author(s)
  Takeshi Takahashi
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis2023
- Author(s)
  Quah Hong Sheng、Cao Elaine Yiqun、Suteja Lisda、Li Constance H.、Leong Hui Sun、Chong Fui Teen、Gupta Shilpi、Arcinas Camille、Ouyang John F.、Ang Vivian、Celhar Teja、Zhao Yunqian、Tay Hui Chen、Chan Jerry、Takahashi Takeshi、Tan Daniel S. W.、Biswas Subhra K.、Rackham Owen J. L.、Iyer N. Gopalakrishna
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1680-1680
- DOI
  10.1038/s41467-023-37379-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396
[Journal Article] Efficient differentiation of human neutrophils with recapitulation of emergency granulopoiesis in human G-CSF knockin humanized mice2022
- Author(s)
  Ito Ryoji、Katano Ikumi、Kwok Immanuel W.H.、Ng Lai Guan、Ida-Tanaka Miyuki、Ohno Yusuke、Mu Yunmei、Celhar Teja、Yen Chan Jerry Kok、Takahashi Takeshi、Goto Motohito、Ogura Tomoyuki、Takahashi Riichi、Ito Mamoru
- Journal Title
  
  Cell Reports
  
  Volume: 41 Issue: 12 Pages: 111841-111841
- DOI
  10.1016/j.celrep.2022.111841
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396, KAKENHI-PROJECT-20K06477
[Journal Article] Establishment of Human Leukocyte Antigen-Mismatched Immune Responses after Transplantation of Human Liver Bud in Humanized Mouse Models2021
- Author(s)
  Mori A, Murata S, Tashiro N, Tadokoro T, Okamoto S, Otsuka R, Wada H, Murata T, Takahashi T, Seino KI, Taniguchi H.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 2 Pages: 476-476
- DOI
  10.3390/cells10020476
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02368, KAKENHI-PROJECT-18H02874, KAKENHI-PROJECT-19K22666
[Journal Article] Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse2020
- Author(s)
  Katano Ikumi、Ito Ryoji、Kawai Kenji、Takahashi Takeshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1-9
- DOI
  10.3389/fimmu.2020.532684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-18H02368
[Journal Article] Hepatitis C virus infection suppresses hepatitis B virus replication via the RIG-I-like helicase pathway2020
- Author(s)
  Murai Kazuhiro、Hikita Hayato、Kai Yugo、Kondo Yasuteru、Fukuoka Makoto、Fukutomi Keisuke、Doi Akira、Yamai Takuo、Nakabori Tasuku、Fukuda Ryo、Takahashi Takeshi、Miyakawa Kei、Suemizu Hiroshi、Ryo Akihide、Yamada Ryoko、Kodama Takahiro、Sakamori Ryotaro、Tatsumi Tomohide、Takehara Tetsuo
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 941-941
- DOI
  10.1038/s41598-020-57603-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08374, KAKENHI-PROJECT-17K09424, KAKENHI-PROJECT-18H02368
[Journal Article] Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice2020
- Author(s)
  Ito Ryoji、Katano Ikumi、Otsuka Iyo、Takahashi Takeshi、Suemizu Hiroshi、Ito Mamoru、Simons Peter J
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 3 Pages: 183-189
- DOI
  10.1093/intimm/dxaa067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-18H02368
[Journal Article] Exacerbation of pathogenic Th17-cell-mediated cutaneous graft-versus-host-disease in human IL-1β and IL-23 transgenic humanized mice.2019
- Author(s)
  Ito R, Katano I, Otsuka I, Hanazawa A, Takahashi T, Kawai K, Yagoto M, Goto M, Ogura T, Takahashi R, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 516 Issue: 2 Pages: 480-485
- DOI
  10.1016/j.bbrc.2019.06.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-18H02368
[Journal Article] Recent Advances in Allergy Research Using Humanized Mice2019
- Author(s)
  Ito Ryoji、Maruoka Shuichiro、Gon Yasuhiro、Katano Ikumi、Takahashi Takeshi、Ito Mamoru、Izuhara Kenji、Nunomura Satoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 11 Pages: 2740-2740
- DOI
  10.3390/ijms20112740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K08613, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-18H02368
[Journal Article] SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells.2017
- Author(s)
  Tokue M, Ikami K, Mizuno S, Takagi C, Miyagi A, Takada R, Noda C, Kitadate Y, Hara K, Mizuguchi H, Sato T, Taketo MM, Sugiyama F, Ogawa T, Kobayashi S, Ueno N, Takahashi S, Takada S, Yoshida S.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 8 Issue: 3 Pages: 561-575
- DOI
  10.1016/j.stemcr.2017.01.006
- NAID
  120005997826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01523, KAKENHI-PLANNED-15H05865, KAKENHI-PLANNED-25114004, KAKENHI-PLANNED-25114007, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04380, KAKENHI-PROJECT-26713012, KAKENHI-PROJECT-26450453, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H00596, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-24111002, KAKENHI-PUBLICLY-17H05782, KAKENHI-PLANNED-25114002
[Journal Article] A novel xenogeneic graft-versus-host disease model for investigating the pathological role of human CD4+ or CD8+ T cells using immunodeficient NOG mice.2017
- Author(s)
  Ito R, Katano I, Kawai K, Yagoto M, Takahashi T, Ka Y, Ogura T, Takahashi R, Ito M
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 5 Issue: 5 Pages: 1216-1228
- DOI
  10.1111/ajt.14116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034, KAKENHI-PROJECT-16K07103, KAKENHI-PROJECT-16K18405, KAKENHI-PROJECT-17H03571
[Journal Article] Generation of CRISPR/Cas9-mediated bicistronic knock-in <i>ins1-cre</i> driver mice2016
- Author(s)
  Yoshikazu Hasegawa, Yoshikazu Hoshino, Abdelaziz E. Ibrahim, Kanako Kato, Yoko Daitoku1, Yoko Tanimoto, Yoshihisa Ikeda, Hisashi Oishi, Satoru Takahashi, Atsushi Yoshiki, Ken-ichi Yagami, Hiroyoshi Iseki, Seiya Mizuno, Fumihiro Sugiyama
- Journal Title
  
  Exp. Anim.
  
  Volume: 65 Issue: 3 Pages: 319-327
- DOI
  10.1538/expanim.16-0016
- NAID
  130006882371
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14359, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26290028, KAKENHI-PROJECT-26460356, KAKENHI-PROJECT-15K20888, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K14588
[Journal Article] Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs.2016
- Author(s)
  Sakie Ohmura, Seiya Mizuno, Hisashi Oishi, Chia-Jui Ku, Mary Hermann, Tomonori Hosoya, Satoru Takahashi, James Douglas Engel
- Journal Title
  
  the journal of clinical investigation
  
  Volume: 126 Issue: 3 Pages: 865-878
- DOI
  10.1172/jci83894
- NAID
  120007129597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-26220207
[Journal Article] Sodium taurocholate cotransporting polypeptide inhibition efficiently blocks hepatitis B virus spread in mice with a humanized liver2016
- Author(s)
  Tasuku Nakabori, Hayato Hikita, Kazuhiro Murai, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Yoshinobu Saito, Satoshi Tanaka, Hiroshi Wada, Hidetoshi Eguchi, Takeshi Takahashi, Hiroshi Suemizu, Ryotaro Sakamori, Naoki Hiramatsu, Tomohide Tatsumi, and Tetsuo Takehara
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 27782-27782
- DOI
  10.1038/srep27782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290034
[Journal Article] Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing.2016
- Author(s)
  Sato K, Oiwa R, Kumita W, Henry R, Sakuma T, Ito R, Nozu R, Inoue T, Katano I, Sato K, Okahara N, Okahara J, Shimizu Y, Yamamoto M, Hanazawa K, Kawakami T, Kametani Y, Suzuki R, Takahashi T, Weinstein EJ, Yamamoto T, Sakakibara Y, Habu S, Hata J, Okano H, Sasaki E.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 19 Issue: 1 Pages: 127-138
- DOI
  10.1016/j.stem.2016.06.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034, KAKENHI-PROJECT-16K07103, KAKENHI-PROJECT-16K18405, KAKENHI-PROJECT-16K18478
[Journal Article] The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice.2015
- Author(s)
  Yokoyama Y, Miyagi T, Hikita H, Yoshioka T, Mukai K, Nawa T, Sakamori R, Ohkawa K, Hiramatsu N, Takahashi T, Suemizu H, Ryo A, Tatsumi T, Takehara T.
- Journal Title
  
  PLoS One.
  
  Volume: 10(12) Issue: 12 Pages: e0144775-e0144775
- DOI
  10.1371/journal.pone.0144775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461002, KAKENHI-PROJECT-26290034
[Journal Article] Visualization of the human CD4(+) T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/gammac(null) (NOG) mice by retrogenic expression of the human TCR gene2015
- Author(s)
  Takahashi, T. Katano, I. Ito, R. Ito, M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 456 Issue: 1 Pages: 219-224
- DOI
  10.1016/j.bbrc.2014.11.062
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-25871075, KAKENHI-PROJECT-26290034
[Journal Article] Predominant Development of Mature and Functional Human NK Cells in a Novel Human IL-2-Producing Transgenic NOG Mouse2015
- Author(s)
  Katano, I. Takahashi, T. Ito, R. Kamisako, T. Mizusawa, T. Ka, Y. Ogura, T. Suemizu, H. Kawakami, Y. Ito, M.
- Journal Title
  
  J Immunol
  
  Volume: 194 Issue: 7 Pages: 3513-3525
- DOI
  10.4049/jimmunol.1401323
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-25871075, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-26290034, KAKENHI-PROJECT-25430099
[Journal Article] Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation2015
- Author(s)
  Seiya Mizuno, Kohei Takami, Yoko Daitoku, Yoko Tanimoto, Tra Thi Huong Dinh, Saori Mizuno-Iijima, Yoshikazu Hasegawa, Satoru Takahashi, Fumihiro Sugiyama, Ken-ichi Yagami
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 13632-13632
- DOI
  10.1038/srep13632
- NAID
  120007136187
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26640050, KAKENHI-PROJECT-26290028
[Journal Article] Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system.2014
- Author(s)
  Mizuno S, Dinh TT, Kato K, Mizuno-Iijima S, Tanimoto Y, Daitoku Y, Hoshino Y, Ikawa M, Takahashi S, Sugiyama F, Yagami KI.
- Journal Title
  
  Mamm Genome.
  
  Volume: 25 Issue: 7-8 Pages: 327-34
- DOI
  10.1007/s00335-014-9524-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-26870077
[Journal Article] NOD-Rag2(null) IL-2Rgamma(null) Mice: An Alternative to NOG Mice for Generation of Humanized Mice2014
- Author(s)
  Katano, I. Ito, R. Kamisako, T. Eto, T. Ogura, T. Kawai, K. Suemizu, H. Takahashi, T. Kawakami, Y. Ito, M.
- Journal Title
  
  Exp Anim
  
  Volume: 63 Pages: 321-30
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] Y-Chromosome-linked B- and NK-cell deficiency in mice2013
- Author(s)
  Shu-lan Sun, Satoshi Horino, Ari Nakadai, Takeshi Kawabe, Atsuko Asao, Takeshi Takahashi, Takanori So, Ryo Funayama, and Naoto Ishii
- Journal Title
  
  Journal of Immunology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Establishment of a Human Allergy Model Using Human IL-3/GM-CSF-Transgenic NOG Mice2013
- Author(s)
  Ito R, Takahashi T, Katano I, Kawai K, Kamisako T, Ogura T, Ida-Tanaka M, Suemizu H, Nunomura S, Ra C, Mori A, Aiso S, Ito M
- Journal Title
  
  Journal of Immunology
  
  Volume: 191 Pages: 2890-2899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells.2013
- Author(s)
  Hirose, S., N. Takayama, S. Nakamura, K. Nagasawa, K. Ochi, S. Hirata, S. Yamazaki, T. Yamaguchi, M. Otsu, S. Sano, N. Takahashi, A. Sawaguchi, M. Ito, T. Kato, H. Nakauchi, and K. Eto.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 1 Issue: 6 Pages: 499-508
- DOI
  10.1016/j.stemcr.2013.10.010
- NAID
  120005350227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells2013
- Author(s)
  Kawabe T, Sun SL, Fujita T, Yamaki S, Asao A, Takahashi T, So T, Ishii N
- Journal Title
  
  Journal of Immunology
  
  Volume: 190 Pages: 5788-5798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Establishment of a Human Allergy Model Using Human IL-3/GM-CSF-Transgenic NOG Mice.2013
- Author(s)
  Ito, R., T. Takahashi, I. Katano, K. Kawai, T. Kamisako, T. Ogura, M. Ida-Tanaka, H. Suemizu, S. Nunomura, C. Ra, A. Mori, S. Aiso, and M. Ito.
- Journal Title
  
  J Immunol
  
  Volume: 191 Issue: 6 Pages: 2890-2899
- DOI
  10.4049/jimmunol.1203543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-23590561, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-25871075
[Journal Article] Y-Chromosome-linked B- and NK-cell deficiency in mice2013
- Author(s)
  Sun SL, Horino S, Nakadai A, Kawabe T, Asao A, Takahashi T, So T, Funayama R, Ishii N
- Journal Title
  
  Journal of Immunology
  
  Volume: 190 Pages: 6209-6220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells2013
- Author(s)
  Takeshi Kawabe, Shu-lan Sun, Tsuyoshi Fujita, Satoshi Yamaki, Atsuko Asao, Takeshi Takahashi, Takanori So, and Naoto Ishii
- Journal Title
  
  Journal of Immunology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse2012
- Author(s)
  Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K
- Journal Title
  
  Int Immunol
  
  Volume: 24 Pages: 243-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γc^<null> mouse2012
- Author(s)
  Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K.
- Journal Title
  
  Int Immunol
  
  Volume: 24 Issue: 4 Pages: 243-52
- DOI
  10.1093/intimm/dxs045
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059005, KAKENHI-PROJECT-21390114, KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458, KAKENHI-PROJECT-23590561, KAKENHI-PROJECT-24390118, KAKENHI-PROJECT-24659487
[Journal Article] Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice2012
- Author(s)
  Moriya K, Suzuki M, Watanabe Y, Takahashi T, Aoki Y, Uchiyama T, Kumaki S, Sasahara Y, Minegishi M, Kure S, Tsuchiya S, Sugamura K, Ishii N
- Journal Title
  
  PLoS One
  
  Volume: 7(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] Current advances in humanized mouse models2012
- Author(s)
  Ito R, Takahashi T, Katano I, Ito M
- Journal Title
  
  Cell Mol Immunol
  
  Volume: 9(3) Pages: 208-214
- Data Source
  KAKENHI-PROJECT-23590561
[Journal Article] In vivo assay of human NK-dependent ADCC using NOD/SCID/gammac(null) (NOG) mice.2010
- Author(s)
  Shiokawa M, Takahashi T, Murakami A, Kita S, Ito M, Sugamura K, Ishii N.
- Journal Title
  
  Biochem Biophys Res Commun. 399
  
  Pages: 733-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590484
[Journal Article] Characterization of the epithelial cell adhesion molecule (EpCAM)+ cell population in hepatocellular carcinoma cell lines.2010
- Author(s)
  Kimura O, Takahashi T, Ishii N, Inoue Y, Ueno Y, Kogure T, Fukushima K, Shiina M, Yamagiwa Y, Kondo Y, Inoue J, Kakazu E, Iwasaki T, Kawagishi N, Shimosegawa T, Sugamura K.
- Journal Title
  
  Cancer Science 101
  
  Pages: 2045-2155
- NAID
  10027832222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590484
[Journal Article] In vivo assay of human NK-dependent ADCC using NODISCIDlgammac(null)(NOG)mice.2010
- Author(s)
  Shiokawa M, Takahashi T, Murakami A, KitほS, Ito M, Sugamura K, Ishii N
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 399 Pages: 733-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590484
[Journal Article] The analysis of the functions of human B andT cells in humanizedNOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice).2009
- Author(s)
  Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K.
- Journal Title
  
  Int.Immunol. 21
  
  Pages: 843-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590484
[Journal Article] The analysis of human B and T cells in humanized NOG mice (hu-HSC NOG mice)2009
- Author(s)
  Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K
- Journal Title
  
  International Immunology 21
  
  Pages: 843-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590484
[Journal Article] Co-inhibitory roles for Glucocorticoid-induced TNF receptor (GITR) in CD1d-dependent natural killer T cells2008
- Author(s)
  Chen, S., Ndhlovu, L.C., Takahashi, T., Takeda, K., Ikarashi, Y., Kikuchi, T., Murata, K., Pandolfi, P.P., Riccardi, C., Ono, M., Sugamura, K. and Ishii, N.
- Journal Title
  
  Eur. J. Immunol. 38
  
  Pages: 2229-2240
- Data Source
  KAKENHI-PROJECT-19590488
[Journal Article] Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction : Part 1.2006
- Author(s)
  Sakaguchi, S., Sakaguchi, N., Yoshitomi, H., Hata, H., Takahashi, T., Nomura, T.
- Journal Title
  
  Semin. Immunol. 18
  
  Pages: 199-206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] 「研究成果報告書概要(欧文)」より2006
- Author(s)
  Sakaguchi, S., Takahashi, T., Hata, H., Yoshitomi, H., Tanaka, S., Hirota, K.
- Journal Title
  
  Birkhaeuser Verlag, Basel
  
  Pages: 147-159
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica.2006
- Author(s)
  Takahashi, T. et. al.
- Journal Title
  
  Tohoku J. Exp. Med. 210
  
  Pages: 307-313
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390148
[Journal Article] Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease..2006
- Author(s)
  Sakaguchi, S., Ono, M., Setoguchi, R., Hori, S., Fehervari, Z., Shimizu, J., Takahashi, T., Nomura, T.
- Journal Title
  
  Immunol. Rev. 212
  
  Pages: 8-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Establishment of a new sensitive assay for anto-human aquaporin-4 antibody in neuromyelitis optica2006
- Author(s)
  Takahashi, T, et. al.
- Journal Title
  
  Tohoku. J. Exp. Med 210
  
  Pages: 307-313
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390148
[Journal Article] Preferential involvement of Tim-3 in the regulation of hepatic CD8^+ T cells in murine acute graft-versus-host disease.2006
- Author(s)
  Oikawa T, Kamimura Y, Akiba H, Yagita H, Okumura K, Takahashi H, Zeniya M, Tajiri H, Azuma M.
- Journal Title
  
  J. Immun 177
  
  Pages: 4281-4287
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Development of Autoimmunity against Transcriptionally Unrepressed Target Antigen in the Thymus of Aire-Deficient Mice..2005
- Author(s)
  Kuroda N, Mitani T, Takeda N, Ishimaru N, Arakaki R, Hayashi Y, Bando Y, Izumi K, Takahashi T, Nomura T, Sakaguchi S, Ueno T, Takahama Y, Uchida D, Sun S, Kajiura F, Mouri Y, Han H, Matsushima A, Yamada G, Matsumoto M.
- Journal Title
  
  J. Immunol. 174
  
  Pages: 1862-1870
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization.2005
- Author(s)
  Setoguchi, R., Hori, S., Takahashi, T., Sakaguchi, S.
- Journal Title
  
  J. Exp. Med. 201
  
  Pages: 723-735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] A crucial role of IL-2 in the homeostatic maintenance of CD25+CD4+ regulatory T cells.2004
- Author(s)
  Setoguchi, R., Hori, S., Takahashi, T., Sakaguchi, S.
- Journal Title
  
  mmunology2004. MedimondI S.r.1., Bologna, Italy.
  
  Pages: 341-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Costimulation via glucocorticoid-induced tumor necrosis factor receptor (GITR) in both conventional and CD25^+ regulatory CD4^+ T cells.2004
- Author(s)
  Kanamaru F, Youngnak P, Takahashi T, Sakaguchi S, Ishikawa I, Azuma M.
- Journal Title
  
  J. Immunol 172
  
  Pages: 7306-7314
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells.2004
- Author(s)
  Kanamaru, F., Youngnak, P., Hashiguchi, M., Nishioka, T., Takahashi, T., Sakaguchi.S., Ishikawa, I., Azuma, M.
- Journal Title
  
  J. Immunol. 172
  
  Pages: 7306-7314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] The expression of B7-H1 on keratinocytes in chronic inflammatory mucocutaneous disease and its regulatory role.2004
- Author(s)
  Youngnak-Piboonratanakit P, Tsushima F, Otsuki N, Igarashi H, Machida U, Iwai H, Takahashi Y, Okura K, Yokozeki H, Azuma M.
- Journal Title
  
  Immunol. Let 94(3)
  
  Pages: 215-222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Italy.2004
- Author(s)
  Sakaguchi, N., Takahashi, T., Hata, H., Nomura, T., Tagami, T., Yamazaki, S.
- Journal Title
  
  Immunology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Naturally arising CD25+CD4+ regulatory T cells in maintaining immunologic self-tolerance and preventing autoimmune disease..2003
- Author(s)
  Takahashi, T., Sakaguchi, S.
- Journal Title
  
  Curr. Mol. Med. 3
  
  Pages: 693-706
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] The role of regulatory T cells in controlling immunologic self-tolerance..2003
- Author(s)
  Takahashi, T., Sakaguchi, S.
- Journal Title
  
  Int. Rev. Cytol. 225
  
  Pages: 1-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Control of autoimunity by natural regulatory T cells.2003
- Author(s)
  Hori, S., Takahashi, T., Sakaguchi, S
- Journal Title
  
  Adv. Immunol. 81
  
  Pages: 329-369
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Naturally arising CD25^+CD4^+ regulatory T cells in maintaining immunologic self-tolerance and preventing autoimmune disease.2003
- Author(s)
  Takahashi, T., Sakaguchi, S
- Journal Title
  
  Curr. Mol. Med. 3
  
  Pages: 693-706
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Thymic generation and selection of CD25+CD4+ regulatory T cells : Implications of their broad repertoire and high self-reactivity for the maintenance of immunologic self-tolerance..2003
- Author(s)
  Sakaguchi, S., Hori, S., Fukui, Y., Sasazuki, T., Sakaguchi, N., Takahashi, T.
- Journal Title
  
  Novartis Foundation Symposium. 252 252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] The role of regulatory T cells in controlling immunologic self-tolerance.2003
- Author(s)
  Takahashi, T., Sakaguchi, S
- Journal Title
  
  Int. Rev. Cytol 225
  
  Pages: 1-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses.2003
- Author(s)
  Tsushima F, Iwai H, Otsuki N, Abe M, Hirose S, Yamazaki T, Akiba H, Yagita H, Takahashi Y, Omura K, Okumura K, Azuma M.
- Journal Title
  
  Eur. J. Immunol 33
  
  Pages: 2773-2782
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Control of autoimunity by natural regulatory T cells..2003
- Author(s)
  Hori, S., Takahashi, T., Sakaguchi, S.
- Journal Title
  
  Adv. Immunol. 81
  
  Pages: 329-369
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice.2003
- Author(s)
  Sakaguchi, N., Takahashi, T., Hata, H., Nomura, T., Tagami, T., Yamazaki, S., Sakihama, T., Matsutani, T., Negishi, I., Nakatsuru, S., Sakaguchi, S.
- Journal Title
  
  Nature. 426
  
  Pages: 454-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Stimulation of CD25^+ CD4^+ regulatory T cells through GITR breaks immunological self-tolerance.2002
- Author(s)
  Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., Sakaguchi, S.
- Journal Title
  
  Nat Immunol. 3
  
  Pages: 135-142
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Stimulation of CD25+ CD4+ regulatory T cells through GITR breaks immunological self-tolerance.2002
- Author(s)
  Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., Sakaguchi, S.
- Journal Title
  
  Nat Immunol. 3
  
  Pages: 135-142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD3OL, CD27L, OX4OL, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.2001
- Author(s)
  Seko Y, Takahashi N, Oshima H, Shimozato 0, Akiba H, Takeda K, Kobata T, Yagita H, Okumura K, Azuma M, Nagai R.
- Journal Title
  
  J Pathol. 195
  
  Pages: 593-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.2001
- Author(s)
  Seko Y, Takahashi N, Oshima H, Shimozato O, Akiba H, Takeda K, Kobata T, Yagita H, Okumura K, Azuma M, Nagai R.
- Journal Title
  
  J Pathol 195
  
  Pages: 593-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Transgene-mediated hyper-expression of IL-5 inhibits autoimmune disease, but increases the risk of B-cell chronic lymphocytic leukemia in a model of murine lupus.
- Author(s)
  Takahashi K, Abe M, Ohtsuji M, Nishimura H, Takatsu K, Shirai T, Hirose S
- Journal Title
  
  Eur. J. Immunol. 34
  
  Pages: 2740-2749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Preferential contribution of B7-H1 to programmed death・mediated regulation of hapten-specific allergic inflammatory responses. '
- Author(s)
  Tsushima F, Iwai H, Otsuki N, Abe M, Hirose S, Yamazaki T, Akiba H, Yagita 2003 Takahashi Y, Omura K, Okumura K, Azuma M
- Journal Title
  
  Eur. J. Immunl. 33
  
  Pages: 2773-2782
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Journal Article] Genetic dissection of anxiety in autoimmune disease.
- Author(s)
  Nakamura K, Xiu Y, Ohtsuji M, Sugita Abe M, Ohtsuji N, Hamano Y, 2003 Jiang Y, Takahashi N, Shirai T, Nishimura H, Hirose S.
- Journal Title
  
  Hum. Mol. Genet. 12
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13140203
[Patent] 免疫不全マウス2018
- Inventor(s)
  高橋武司
- Industrial Property Rights Holder
  公益財団法人実験動物中央研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-181930
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] A novel ischemic　infarction model using humanized NOG-IL-34 Tg mouse2022
- Author(s)
  Ikumi Katano, Takeshi Takahashi, Mamoru Ito
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02396
[Presentation] Prolonged survival of hRBC in NOG-C3-Clec4f double deficient mice2022
- Author(s)
  Takuya Yamaguchi, Iyo Otsuka, Takeshi Takahashi
- Organizer
  International workshop on humanized mice 6 (IWHM6)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396
[Presentation] A novel humanized mouse model based on NOG-FcγR-/- mice recapitulates anti-tumor immune reactions by human immune systems in response to anti-PD-1 antibody (Nivolumab).2022
- Author(s)
  Ikumi Katano, Asami Hanazawa, Iyo Otsuka, Takuya Yamaguchi, Misa Mochizuki, Kenji Kawai, Ryoji Ito, Motohito Goto, Takahiro Kagawa & Takeshi Takahashi
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396
[Presentation] Functional evaluation model for anti human PD 1 antibody using humanized NOG-FcgR KO mouse2022
- Author(s)
  Ikumi Katano, Asami Hanazawa, Iyo Ootsuka, Misa Mochizuki, Kenji Kawai, Takeshi Takahashi
- Organizer
  International workshop on humanized mice 6 (IWHM6)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396
[Presentation] Development of NOG mice with modifications of innate receptors2022
- Author(s)
  Takeshi Takahashi
- Organizer
  International workshop on humanized mice 6 (IWHM6)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02396
[Presentation] 免疫系ヒト化マウスを用いた抗体医薬品評価2020
- Author(s)
  高橋武司
- Organizer
  第27回HAB研究機構学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] Specific detection of human NK cell mediated in vivo ADCC in FcgR-deficient NOG-human IL-15 transgenic mice2019
- Author(s)
  Ikumi Katano*, Asami Hanazawa, Ryoji Ito, Mamoru Ito, Takeshi Takahashi
- Organizer
  AACR
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] Beta-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/GM-CSF Tg mice2019
- Author(s)
  Ito R, Katano I, Otsuka I, Takahashi T, Ito M, and Simons PJ
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] 抗体受容体欠損型NOG-FｃRKOマウスを用いた抗PD-1抗体の機能評価モデル2019
- Author(s)
  片野いくみ　花澤麻美　大塚伊代　伊藤亮治　位高美香　川井健司　高橋武司
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] Development of human neutrophils in hG-CSF knockin NOG mouse transferred with human HSC2019
- Author(s)
  Ito R, Katano I, Takahashi T, Goto M, Takahashi R, Ito M
- Organizer
  103rd American Association of Immunology
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] Specific detection of human NK cell mediated in vivo ADCC in FcgR-deficient NOG-human IL-15 transgenic mice2018
- Author(s)
  片野いくみ、花澤麻美、伊藤亮治、伊藤守、高橋武司
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] Modification of human hematopoiesis in novel NOG strain2018
- Author(s)
  高橋武司
- Organizer
  International Symposium of Humanized mouse models
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02368
[Presentation] LTi特異的なIL-2Rg鎖発現によるNOGマウスでのリンパ節復元2016
- Author(s)
  高橋武司、杉山文博、水野聖哉、阿部隼人、伊藤守
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] NOG hIL-3/GM-CSF/IL-5Tgマウスを用いたヒト喘息モデルの開発2016
- Author(s)
  伊藤亮治、布村聡、片野いくみ、川井健司、高橋武司、後藤元人、小倉智幸、高橋利一、伊藤守
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] Generation of 2nd generation NOG mice　and application to human immunology2016
- Author(s)
  Takeshi Takahashi
- Organizer
  International symposium of humanized mouse models
- Place of Presentation
  Nanjing, China
- Year and Date
  2016-09-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] Development and applications of novel humanized mice with improved human immune system2016
- Author(s)
  Takeshi Takahashi
- Organizer
  7th AFLAS congress
- Place of Presentation
  Raffles City Convention Center, Singapore
- Year and Date
  2016-11-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] A novel xenogeneic graft-versus-host disease model for investigating the pathological role of human CD4+ or CD8+ T cells using immunodeficient NOG mice.2016
- Author(s)
  Ryoji Ito, Ikumi Katano, Takeshi Takahashi, Mamoru Ito
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] CRISPR/Casを用いたマウスゲノム編集の実際2016
- Author(s)
  水野聖哉、高橋智、杉山文博、八神健一
- Organizer
  第121回日本解剖学会総会全国学術集会
- Place of Presentation
  ビッグパレットふくしま
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] Development of 2nd generation NOG mice in CIEA2016
- Author(s)
  Takeshi Takahashi
- Organizer
  International workshop on humanized mice 5
- Place of Presentation
  Zurich
- Year and Date
  2016-01-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] CRISPR/Cas9システムを用いた多様な遺伝子改変マウス作製の実際2016
- Author(s)
  水野聖哉、高橋智、杉山文博
- Organizer
  生化学会大会
- Place of Presentation
  宮城県仙台市.仙台国際センター
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] Reconstitution of human immune systems in next generation humanized mice and their application2015
- Author(s)
  Takeshi Takahashi
- Organizer
  第14回中華実験動物学会
- Place of Presentation
  台北
- Year and Date
  2015-11-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290034
[Presentation] Applied Genome Editing with CRISPR/Cas9 Plasmid in Mice2015
- Author(s)
  Seiya Mizuno, Kanako Kato, Saori Iijima, Yuko Hamada, Tra Dinh Thi Huong, Yoshikazu Hoshino, Yoko Tanimoto, Satoru Takahashi, Fumihiro Sugiyama, Ken-ichi Yagami
- Organizer
  トランスポゾン転移とゲノム編集技術に関する国際会議2015
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] IgE-mediated allergic responses in human mast cells in humanized NOG mice expressing human IL-3 and GM-CSF2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Satoshi Nunomura, Chisei Ra, Akio Mori, Sadakazu Aiso, Mamoru Ito
- Organizer
  15th International congress of Immunology
- Place of Presentation
  ミラノ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Characterization of human Eosinophil in HSC-transferred NOG-human IL-5 transgenic mice2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Functional NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  15th International congress of Immunology
- Place of Presentation
  ミラノ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 transgenic NOG mice2013
- Author(s)
  TakeshiTakahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスを用いたヒトアレルギーモデルの開発2013
- Author(s)
  伊藤亮治、片野いくみ、高橋武司、川井健司、上迫努、布村聡、相磯貞和、伊藤守
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば/茨城
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Predominant development of mature and functional human NK Cells in a novel human IL-2 producing transgenic NOD-scid,IL-2Rg KO (NOG) mouse.2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Retrogenic expression of human TCR in HLA-DR4 transgenic NOG mice2013
- Author(s)
  高橋武司、片野いくみ、伊藤亮治、伊藤守
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張/千葉
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Human mast cell mediated allergic responses in humanized NOG mouse expressing human IL-3 and GM-CSF2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Characterization of human Eosinophil in HSC-transferred NOG-human IL-5 transgenic mice2013
- Author(s)
  片野いくみ、高橋武司、伊藤亮治、伊藤守
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張/千葉
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Predominant development of mature and functional human NK Cells in a novel human IL-2 producing transgenic NOD-scid,IL-2Rg KO (NOG) mouse2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013
- Author(s)
  TakeshiTakahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice2013
- Author(s)
  TakeshiTakahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  15th International congress of Immunology
- Place of Presentation
  ミラノ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Pathology of cutaneous xeno-GVHD in human CD4 T cell transplanted NOG mice.2013
- Author(s)
  伊藤亮治, 片野いくみ, 高橋武司, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Predominant development of mature and functional human NK Cells in a novel human IL-2 producing transgenic NOD-scid,IL-2Rg KO (NOG) mouse2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice2013
- Author(s)
  TakeshiTakahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Human mast cell mediated allergic responses in humanized NOG mouse expressing human IL-3 and GM-CSF.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Functional NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice.2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Pathology of cutaneous xeno-GVHD in human CD4 T cell transplanted NOG mice.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Mamoru Ito
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 transgenic NOG mice2013
- Author(s)
  高橋武司, 片野いくみ, 伊藤亮治, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Human mast cell mediated allergic responses in humanized NOG mouse expressing human IL-3 and GM-CSF.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Mamoru Ito
- Organizer
  4th International workshop on humanized mice
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013
- Author(s)
  Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Characterization of human Eosinophil in HSC-transferred NOG-human IL-5 transgenic mice2013
- Author(s)
  片野いくみ, 伊藤亮治, 高橋武司, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Functional NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milano
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] IgE-mediated allergic responses in human mast cells in humanized NOG mice expressing human IL-3 and GM-CSF.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Satoshi Nunomura, Chisei Ra, Akio Mori, Sadakazu Aiso, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Pathology of cutaneous xeno-GVHD in human CD4 T cell transplanted NOG mice2013
- Author(s)
  伊藤亮治、片野いくみ、高橋武司、伊藤守
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張/千葉
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] IgE-mediated allergic responses in human mast cells in humanized NOG mice expressing human IL-3 and GM-CSF2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Satoshi Nunomura, Chisei Ra, Akio Mori, Sadakazu Aiso, Mamoru Ito
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milano
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013
- Author(s)
  Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice2013
- Author(s)
  TakeshiTakahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milano
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Homeostatic proliferation occurs iin mesenteric lymph nodes and supplies effector memory CD4 T cells in the intestine2012
- Author(s)
  Takeshi Kawabe, Shu-lan Sun, Satoshi Yamaki, Atsuko Asao, Takeshi Takahashi, Takanori So, and Naoto Ishii
- Organizer
  第４１回日本免疫学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Characteristics of NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice2012
- Author(s)
  Katano Ikumi, Ito Ryoji, Takahashi Takeshi, Ito Mamoru
- Organizer
  第４１回日本免疫学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Functional maturation of human myeloid cells in a NOD/SCID/IL2rgnull(NOG) transgenic humanized mouse strain expressing human IL-3 and GM-CSF2012
- Author(s)
  Ito Ryoji, Takahashi Takeshi, Katano Ikumi, Kawai Kenji, Nunomura Satoshi, Ra Chisei, Kamisako Tsutomu, Aiso Sadakazu, Ito Mamoru
- Organizer
  第４１回日本免疫学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] HLA発現NOGマウスを用いたヒト機能的免疫反応の惹起2012
- Author(s)
  高橋武司
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/γcnull (NOG)-HLA transgenic mice2010
- Author(s)
  Takeshi Takahashi
- Organizer
  国際免疫学会(International Congress of Immunology)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/gamma Cnull(NOG)-HLA transgenic mice.2010
- Author(s)
  Takahashi, T.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/gcnull (NOG)-HLA transgenic mice2010
- Author(s)
  高橋武司、鈴木真紀子、森谷邦彦、片野いくみ、伊藤亮治、伊藤守、菅村和夫、石井直人
- Organizer
  国際免疫学会(International Congress of Immunology)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] The analysis of human B and T cells in humanized NOG mice (hu-HSC NOG mice)2009
- Author(s)
  高橋武司、片野いくみ、伊藤亮治、伊藤守、菅村和夫、石井直人
- Organizer
  2^<nd> international workshop on humanized mice
- Place of Presentation
  オランダアムステルダム
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] Analysis of the functional human T cellsin reconstituted NOG mice2008
- Author(s)
  岡嶋亮良、高橋武司、渡邊庸平、片野いくみ、伊藤亮治、伊藤守、石井直人、菅村和夫
- Organizer
  日本免疫学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] Facilitating the human B cell development in humanized NOG mice2008
- Author(s)
  渡邊庸平、高橋武司、岡嶋亮良、片野いくみ、伊藤亮治、伊藤守、土屋滋、石井直人、菅村和夫
- Organizer
  日本免疫学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] Analysis of the functional human T cells in reconstituted NOG mice Facilitating the human B cell development in humanized NOG mice2008
- Author(s)
  高橋武司
- Organizer
  日本免疫学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20590484
[Presentation] BRGヌードマウスの計画生産および特性データ
- Author(s)
  水澤卓馬、小倉智幸、何裕遥、上迫努、高橋利一、江藤智生、伊藤守、日置恭司
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] 重度免疫不全NOGヘアレスマウスの計画生産および特性データ
- Author(s)
  何裕遥、小倉智幸、水澤卓馬、上迫努、高橋利一、伊東一昭、堤秀樹、江藤智生、伊藤守、日置恭司
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Induction of human humoral immune repsonses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/ｇc null mouse
- Author(s)
  高橋武司
- Organizer
  The 3rd International workshop on humanized mouse
- Place of Presentation
  ピッツバーグ
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] Induction of human humoral immune repsonses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/gc null mouse
- Author(s)
  鈴木真紀子、高橋武司、片野いくみ、伊藤亮治、伊藤守、張替秀郎、石井直人、菅村和夫
- Organizer
  日本免疫学会総会
- Place of Presentation
  千葉幕張
- Data Source
  KAKENHI-PROJECT-23590561
[Presentation] CRISPR/Cas9プラスミドを介したマウスゲノム編集の応用
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・依馬正次・伊川正人・高橋智・杉山文博・八神健一
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] Applied Genome Efiting with CRISPR/Cas9 Plasmid in Mice
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・高橋智・杉山文博・八神健一
- Organizer
  28th International Mammalian Genome Conference
- Place of Presentation
  アメリカメイン州
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] ヒトIL=5遺伝子導入型NOGマウスのヒト好酸球分化能の解析
- Author(s)
  片野いくみ、高橋武司、伊藤亮治、上迫努、何裕遥、小倉智幸、高橋利一、末水洋志、河上裕、伊藤守
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] TK-NOGマウスの計画生産および特性データ
- Author(s)
  富山香代、小倉智幸、何裕遥、上迫努、高橋利一、伊藤守、日置恭司、末水洋志
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒトIL-5遺伝子導入型NOGマウスのヒト好酸球分化能の解析
- Author(s)
  片野いくみ、高橋武司、伊藤亮治、上迫努、何裕遥、小倉智幸、高橋利一、末水洋志、河上裕、伊藤守
- Organizer
  第６１回　実験動物学会
- Place of Presentation
  札幌
- Year and Date
  2014-05-14 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26290034

1. MURATA Kazuko (20137631)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 玉井恵一 (40509262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ITO Mamoru (00176364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
4. ANDO Kiyoshi (70176014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOYANAGI Yoshio (80215417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAMETANI Yoshie (50338787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAHATA Tatsutoshi (20110744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAHATA Takashi (10398753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUEMIZU Hiroshi (40332209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. ETO Tomoo (30370175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. SAKAGUCHI Shimon (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
12. INABA Kayo (00115792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIKUTANI Hitoshi (80161412)

# of Collaborated Projects: 1 results

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14. AZUYMA Miyuki (90255654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
15. HIROSE Sachiko (00127127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. ISHII Naoto (60291267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. MIZUNO Seiya (10633141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. Sugiyama Fumihiro (90226481)

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# of Collaborated Products: 6 results
19. 中野直子 (90222166)

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20. 長船健二 (80502947)

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21. 荒岡利和 (40437661)

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22. ITO Ryoji

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# of Collaborated Products: 21 results
23. KATANO Ikumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
24. Iijima Saori

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
25. Dinh Thi Huong Tra

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HARA Kenshiro

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# of Collaborated Products: 1 results
27. KONDO Yasuteru

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# of Collaborated Products: 1 results
28. 伊川正人

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# of Collaborated Products: 1 results
29. 巽智秀

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# of Collaborated Products: 1 results
30. 阪森亮太郎

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# of Collaborated Products: 1 results
31. 権寧博

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# of Collaborated Products: 1 results
32. 丸岡秀一郎

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# of Collaborated Products: 1 results

Takahashi Takeshi 高橋 武司

TAKAHASHI Takeshi 高橋 武司

高橋 武司 タカハシ タケシ

Research Projects

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Generation and application of humanized kidney mice using iPS cells

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Improvement of humanized mice through elucidation of interaction between mouse innate immune system and human cellsPrincipal Investigator

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Development of highly immunodeficient mice by regulating innate immune systemsPrincipal Investigator

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Induction of human allergic responses in 2nd generation NOG micePrincipal Investigator

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Genetic humanized Mouse production by CRISPITT

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Development of humanized mouse with functional immune systemsPrincipal Investigator

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Development of experimentation systems related to personalized medicine using humanized NOG mice

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The analysis of immune responses in humanized NOG micePrincipal Investigator

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Regulation of APC function by STAM1/2.

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Regulation of effector T cells that mediate inflammatory responses

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CD25+CD4+制御性T細胞による免疫制御機構の分子的基礎Principal Investigator

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Immune tolerance and regulation towards understanding and cure of autoimmune disease

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[Book] Humanized Mice for HIV Research2015

Author(s)

Takahashi Takeshi 高橋武司

TAKAHASHI Takeshi 高橋武司

高橋武司タカハシタケシ