UEYAMA TAKEHIKO 上山健彦

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UEYAMA Takehiko 上山健彦

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Researcher Number	80346254
Other IDs	https://orcid.org/0000-0002-5647-3937
Affiliation (Current)	2025: 神戸大学, バイオシグナル総合研究センター, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 神戸大学, バイオシグナル総合研究センター, 教授 2016 – 2019: 神戸大学, バイオシグナル総合研究センター, 准教授 2015: 神戸大学, 先端融合研究環バイオシグナル研究センター, 准教授 2011 – 2015: 神戸大学, バイオシグナル研究センター, 准教授 2012: 神戸大学, 学内共同利用施設等, 准教授 … More 2012: 神戸大学, 自然科学系先端融合研究環バイオシグナル研究センター, 准教授 2010 – 2011: 神戸大学, 自然科学系先端融合研究環・バイオシグナル研究センター, 准教授 2010: 神戸大学, 自然科学系先端融合研究環バイオシグナル研究センター, 准教授 2007 – 2009: Kobe University, 自然科学系先端融合研究環バイオシグナル研究センター, 講師 2008: Kobe University, 自然科学先端融合研究環バイオシグナル研究センター, 講師 2007 – 2008: 神戸大学, バイオシグナル研究センター, 講師 2005 – 2006: 神戸大学, バイオシグナル研究センター, 助手 2004: 神戸大, 助手 2003: 神戸大学, バイオシグナル研究センター, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48030:Pharmacology-related / Medium-sized Section 46:Neuroscience and related fields / General pharmacology / Biological Sciences / Neurochemistry/Neuropharmacology Except Principal Investigator General pharmacology / Biological Sciences / Basic Section 48030:Pharmacology-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator 活性酸素 / NADPH oxidase / 聴覚 / ROS / 難聴 / DIAPH1 / 遺伝性難聴 / 感音難聴 / DFNA1 / DIA1 … More / 活性酸素種 / 平衡覚 / Rac / 後天性難聴 / 後天性感音難聴 / 左右差 / 視覚 / 視聴覚 / ＤＩＡ１ / 遺伝 / 血液異常 / 進行性難聴 / 聴力 / 内耳有毛細胞 / Rho-family GTPase / アクチン / RhoA / Cdc42 / 耳石 / 聴毛 / 低分子量G蛋白質 / 内耳 / balancing / hearing / inner ear / small GTPases / 貧食細胞 / トランスポートソーム / 貪食細胞 / 膜輸送 / 感染症 / Rac1 / NADPH oxidase(Nox) / 宿主感染防御 / Phagocytosis / PKC / 食胞 / microglia / Fcγ receptor / Diacylglycerol kinase / Protein kinase C / ファゴサイトーシス … More Except Principal Investigator プロテインキナーゼC / モデル動物 / パーキンソン病 / 脊髄小脳変性症 / リン酸化 / PKC / リン酸化プロテオーム / リン酸化酵素 / モデルマウス / アミロイド / 創薬 / 遺伝子変異 / 神経変性 / カルシウム / 遺伝子操作動物 / 脂質 / 小脳プルキンエ細胞 / PLEKHG4 / VCP / SCA / 遺伝性難聴 / 有毛細胞 / 遺伝子導入 / 聴覚 / ゲノム編集 / 遺伝子治療 / 難聴 / 遺伝子 / 内耳 / muscular dystrophy / nox3 / dia1 / hearing / inner ear / CSP alpha / リン酸化抗体 / CSPalpha / シャペロン / HSP70 / AAV / プレシナプス / アデノ随伴ウイルス / CSPa / Hspファミリー / ischemia / Spinocerebellar ataxia / NADPH oxidase / phagocytosis / diacylglycerol kinase / lipid / live imaging / protein kinase C / ファゴサイトーシス / 神経可塑性 / カスケード / 脂質メッセンジャー / GFP / 凝集体形成 / 核移行 / 細胞周期 / ジアシルグリセロール / 虚血 / 小脳脊髄変性症 / NADPHオキシダーゼ / ドン食作用 / ジアシルグリセロールキナーゼ / ライブイメージング / Rac / ケラチノサイト / 分化誘導因子 / 脂肪細胞 / ドーパミン / 質量分析 / 治療薬 / 遺伝子解析 / オートファジー / 乳幼児 / 遺伝子異常 / oxidase / NADPH / 活性酸素 / p40phox / クローン病 / 細胞内情報伝達 / 神経変性疾患 / プロテインキナーゼ / 精髄小脳変性症 / 性ホルモン / 神経 / グリア / 脳虚血 / 蛋白質 / シグナル伝達 / 共焦点顕微鏡 / 可視化 Less

活性酸素産生酵素NOX3の発現制御機序解明による後天性及び片側性難聴の治療法開発Principal Investigator
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Elucidation of acquired SNHL mechanism caused from Nox3-derived ROS and beyondPrincipal Investigator
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Neuroprotective mechanisms mediated by PKC phosphorylation in spinocerebellar degeneration and their application to novel therapies.
- Principal Investigator
  
  Shirafuji Toshihiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Challenge for establishing the criteria of laterality-based diseases in hearing and visionPrincipal Investigator
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Kobe University
Development of a novel treatment for Parkinson's disease focusing on the protective effect of CSPa phosphorylation on synaptic terminal
- Principal Investigator
  
  Shirafuji Toshihiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kobe University
Investigation for gene transfer therapy in inner ears
- Principal Investigator
  
  SAKAGUCHI HIROFUMI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe University
  Kyoto Prefectural University of Medicine
Elucidation of amyloid formation mechanism in Spinocerebellar ataxia and its application to drug therapy
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Mechanism clarification of new symptoms in DFNA1 causing from constitutively active DAI1 mutantsPrincipal Investigator
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Roles of Rho-family small GTPases in establishment and maintenance for hearing and balancingPrincipal Investigator
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Elucidation of a new differentiation mechanism of beige adipocytes and its application for drug design
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Determination of PKC substrate involved in neurodegenerative diseases and its application for drug design
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Roles of p40phox in Crohn disease and its application for drug development
- Principal Investigator
  
  SAITOU Naoaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Roles of small GTPases and ROS in functions anddiseases of inner earPrincipal Investigator
- Principal Investigator
  
  UEYAMA Takehiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Production and analysis of model animals for neurodegenerative diseases caused by dysfunction of PKC and their use for drug design
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
貪食細胞における活性酸素産生トランスポートソームの形成・活性化機構の解明Principal Investigator
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Mechanism and treatment for the disease caused by the impairment of PKC signaling
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Analysis of activation mechanism of new members of NADPH oxidase familyPrincipal Investigator
- Principal Investigator
  
  UEYAMA Takehiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
性ホルモンの神経保護作用におけるグリア・ニューロン内情報伝達クロストーク機構
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
核内脂質シグナル及び核移行蛋白質の可視化システムを用いた細胞周期制御機構の解明
- Principal Investigator
  
  SHIRAI Yasuhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
非貪食細胞の最終分化による活性酸素産生能の獲得とその制御機構の解明Principal Investigator
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Molecular mechanism of cellular response induced by dynamic metabolism of membrane phospholipid
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
ファゴサイトーシス時に働くシグナルカスケードのリアルタイム解析Principal Investigator
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kobe University

[Journal Article] Remodeling of the postsynaptic proteome in male mice and marmosets during synapse development2024
- Author(s)
  Kaizuka Takeshi、Suzuki Takehiro、Kishi Noriyuki、Tamada Kota、Kilimann Manfred W.、Ueyama Takehiko、Watanabe Masahiko、Shimogori Tomomi、Okano Hideyuki、Dohmae Naoshi、Takumi Toru
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2496-2496
- DOI
  10.1038/s41467-024-46529-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0132, KAKENHI-PROJECT-23K06399, KAKENHI-ORGANIZER-21H05238, KAKENHI-PUBLICLY-23H04233, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21H02672
[Journal Article] Dispensable role of Rac1 and Rac3 after cochlear hair cell specification2023
- Author(s)
  Nakamura Takashi, Sakaguchi Hirofumi, Mohri Hiroaki, Ninoyu Yuzuru, Goto Akihiro, Yamaguchi Taro, Hishikawa Yoshitaka, Matsuda Michiyuki, Saito Naoaki, Ueyama Takehiko
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 101 Issue: 7 Pages: 843-854
- DOI
  10.1007/s00109-023-02317-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06738, KAKENHI-PUBLICLY-22H05496, KAKENHI-PROJECT-21H02672
[Journal Article] S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis2023
- Author(s)
  Niki Yoko、Adachi Naoko、Fukata Masaki、Fukata Yuko、Oku Shinichiro、Makino-Okamura Chieko、Takeuchi Seiji、Wakamatsu Kazumasa、Ito Shosuke、Declercq Lieve、Yarosh Daniel B.、Mammone Tomas、Nishigori Chikako、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 143 Issue: 2 Pages: 317-327.e6
- DOI
  10.1016/j.jid.2022.08.040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06858, KAKENHI-PROJECT-20H00459, KAKENHI-PROJECT-21H02672, KAKENHI-PROJECT-16KK0181, KAKENHI-PROJECT-23K23986
[Journal Article] Loss of synaptic ribbons is an early cause in ROS-induced acquired sensorineural hearing loss2023
- Author(s)
  Kurasawa Shunkou、Mohri Hiroaki、Tabuchi Keiji、Ueyama Takehiko
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 186 Pages: 106280-106280
- DOI
  10.1016/j.nbd.2023.106280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02672
[Journal Article] Effects of flurbiprofen on the functional regulation of serotonin transporter and its misfolded mutant2022
- Author(s)
  Hirakawa Haruki、Taguchi Kei、Murakawa Seiya、Asano Masaya、Noguchi Soma、Kikkawa Satoshi、Harada Kana、Adachi Naoko、Ueyama Takehiko、Hide Izumi、Tanaka Shigeru、Sakai Norio
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 1 Pages: 187-195
- DOI
  10.1016/j.jphs.2021.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-19H03409, KAKENHI-PROJECT-21H02672, KAKENHI-PROJECT-21K06802, KAKENHI-PROJECT-21K07274
[Journal Article] Late‐onset hearing loss case associated with a heterozygous truncating variant of <scp> <i>DIAPH1</i> </scp>2022
- Author(s)
  Kim Bong Jik、Miyoshi Takushi、Chaudhry Taimur、Friedman Thomas B.、Choi Byung Yoon、Ueyama Takehiko
- Journal Title
  
  Clinical Genetics
  
  Volume: 101 Issue: 4 Pages: 466-471
- DOI
  10.1111/cge.14115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02672
[Journal Article] Nox3-Derived Superoxide in Cochleae Induces Sensorineural Hearing Loss2021
- Author(s)
  Mohri Hiroaki、Ninoyu Yuzuru、Sakaguchi Hirofumi、Hirano Shigeru、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 21 Pages: 4716-4731
- DOI
  10.1523/jneurosci.2672-20.2021
- NAID
  120007097047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-21H02672
[Journal Article] Nox3-derived superoxide in cochleae induces sensorineural hearing loss.2021
- Author(s)
  Mohri H, Ninoyu Y, Sakaguchi H, Hirano S, Saito N, Ueyama T
- Journal Title
  
  J. Neurosci.
  
  Volume: JN-RM-2672-20
- NAID
  120007097047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09383
[Journal Article] Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes2020
- Author(s)
  Ueyama Takehiko、Sakuma Megumi、Nakatsuji Mio、Uebi Tatsuya、Hamada Takeshi、Aiba Atsu、Saito Naoaki
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 140 Issue: 1 Pages: 75-84.e6
- DOI
  10.1016/j.jid.2019.06.140
- NAID
  120006733143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] The integrity of cochlear hair cells is established and maintained through the localization of Dia1 at apical junctional complexes and stereocilia2020
- Author(s)
  Ninoyu Yuzuru、Sakaguchi Hirofumi、Lin Chen、Suzuki Toshiaki、Hirano Shigeru、Hisa Yasuo、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  Cell Death & Disease
  
  Volume: 11 Issue: 7 Pages: 1-15
- DOI
  10.1038/s41419-020-02743-z
- NAID
  120006877483
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-18K09383, KAKENHI-PROJECT-18K16851
[Journal Article] Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy2020
- Author(s)
  Morioka Shigefumi、Sakaguchi Hirofumi、Mohri Hiroaki、Taniguchi-Ikeda Mariko、Kanagawa Motoi、Suzuki Toshiaki、Miyagoe-Suzuki Yuko、Toda Tatsushi、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 5 Pages: 1-28
- DOI
  10.1371/journal.pgen.1008826
- NAID
  120006863578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-18K07790, KAKENHI-PROJECT-18K09383, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19K07519
[Journal Article] Rho-family small GTPases: from highly polarized sensory neurons to cancer cells2019
- Author(s)
  Ueyama T
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 2 Pages: 92-92
- DOI
  10.3390/cells8020092
- NAID
  120006599240
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04042
[Journal Article] Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene2019
- Author(s)
  Shirafuji Toshihiko、Shimazaki Haruo、Miyagi Tatsuhiro、Ueyama Takehiko、Adachi Naoko、Tanaka Shigeru、Hide Izumi、Saito Naoaki、Sakai Norio
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 98 Pages: 46-53
- DOI
  10.1016/j.mcn.2019.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06700, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-18K07392, KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-19H03409
[Journal Article] Differential disruption of autoinhibition and defect in assembly of cytoskeleton during cell division decide the fate of human DIAPH1-related cytoskeletopathy2019
- Author(s)
  Kim Bong Jik、Ueyama Takehiko、Miyoshi Takushi、Lee Seungmin、Han Jin Hee、Park Hye-Rim、Kim Ah Reum、Oh Jayoung、Kim Min Young、Kang Yong Seok、Oh Doo Yi、Yun Jiwon、Hwang Sang Mee、Kim Nayoung K D、Park Woong-Yang、Kitajiri Shin-ichiro、Choi Byung Yoon
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 56 Issue: 12 Pages: 818-827
- DOI
  10.1136/jmedgenet-2019-106282
- NAID
  120007032326
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-17H04345
[Journal Article] Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene2019
- Author(s)
  Shirafuji T, Shimazaki H, Miyagi T, Ueyama T, Adachi N, Tanaka T, Hide I, Saito S, Sakai S
- Journal Title
  
  Mol. Cell. Neurosci.
  
  Volume: 98 Pages: 46-53
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04032
[Journal Article] Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 142018
- Author(s)
  Nakazono, A., Adachi, N., Takahashi, H., Seki, T., Hamada, D., Ueyama, T., Sakai, N. and Saito, N.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 293 Issue: 38 Pages: 14758-14774
- DOI
  10.1074/jbc.ra118.002913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-16K08276, KAKENHI-PROJECT-16K15318
[Journal Article] Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis2018
- Author(s)
  Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N
- Journal Title
  
  Exp. Neurol.
  
  Volume: 302 Pages: 57-67
- NAID
  120006733139
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04042
[Journal Article] Hearing vulnerability after noise exposure in a mouse model of reactive oxygen species overproduction2018
- Author(s)
  Morioka Shigefumi、Sakaguchi Hirofumi、Yamaguchi Taro、Ninoyu Yuzuru、Mohri Hiroaki、Nakamura Takashi、Hisa Yasuo、Ogita Kiyokazu、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 146 Issue: 4 Pages: 459-473
- DOI
  10.1111/jnc.14451
- NAID
  120006545101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-16K08288
[Journal Article] The Role of Cysteine String Protein Alpha (CSPα) Phosphorylation at Serine 10, and 34, by Protein Kinase Cγ for Presynaptic Maintenance.2018
- Author(s)
  Shirafuji T, Ueyama T, Adachi N, Yoshino KI, Sotomaru Y, Uwada J, Kaneoka A, Ueda T, Tanaka S, Hide I, Saito N, Sakai N
- Journal Title
  
  J. Neurosci.
  
  Volume: 38 Issue: 2 Pages: 278-290
- DOI
  10.1523/jneurosci.1649-17.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08234, KAKENHI-PROJECT-16K19012, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-15K09317, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-16K15318
[Journal Article] Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis. Exp. Neurol.2018
- Author(s)
  Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N.
- Journal Title
  
  Exp. Neurol.
  
  Volume: 302 Pages: 57-67
- DOI
  10.1016/j.expneurol.2017.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-17H04032
[Journal Article] Golgi-Associated Protein Kinase C-ε Is Delivered to Phagocytic Cups: Role of Phosphatidylinositol 4-Phosphate2017
- Author(s)
  Hanes Cheryl M.、D’Amico Anna E.、Ueyama Takehiko、Wong Alexander C.、Zhang Xuexin、Hynes W. Frederick、Barroso Margarida M.、Cady Nathaniel C.、Trebak Mohamed、Saito Naoaki、Lennartz Michelle R.
- Journal Title
  
  J. Immunol
  
  Volume: 199 Issue: 1 Pages: 271-277
- DOI
  10.4049/jimmunol.1700243
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] Validation of Anti-CSPα, SNAP25, Tyrosine Hydroxylase, Ubiquitin, Cleaved Caspase 3, and pSer PKC Motif Antibodies for Utilization in Western Blotting2017
- Author(s)
  Shirafuji T, Ueyama T, Tanaka S, Hide I, Saito N and Sakai N
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 50 Issue: 6 Pages: 177-180
- DOI
  10.1267/ahc.17028
- NAID
  130006285168
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08234, KAKENHI-PROJECT-16K15318, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-15K09317
[Journal Article] Novel role of Rac-Mid1 signaling in medial cerebellar development.2017
- Author(s)
  Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.
- Journal Title
  
  Development
  
  Volume: 144 Issue: 10 Pages: 1863-1875
- DOI
  10.1242/dev.147900
- NAID
  120006363303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08471, KAKENHI-PLANNED-25115010, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury2017
- Author(s)
  Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N
- Journal Title
  
  J Biol Chem
  
  Volume: 292 Issue: 4 Pages: 1240-1250
- DOI
  10.1074/jbc.m116.748871
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04032
[Journal Article] Identification and characterization of PKCγ, a kinase associated with SCA14, as　an amyloidogenic protein.2015
- Author(s)
  Takahashi H, Adachi N, Shirafuji T, Danno S, Ueyama T, Vendruscolo M, Shuvaev AN, Sugimoto T, Seki T, Hamada D, Irie K, Hirai H, Sakai N, *Saito N.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 24 Issue: 2 Pages: 525-539
- DOI
  10.1093/hmg/ddu472
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25430065, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124, KAKENHI-PROJECT-26440076, KAKENHI-PROJECT-25293061
[Journal Article] The Extracellular A-loop of Dual Oxidases Affects the Specificity of Reactive Oxygen Species Release.2015
- Author(s)
  Ueyama T, Sakuma M, Ninoyu Y, Hamada T, Dupuy C, Geiszt M, Leto TL, Saito N.
- Journal Title
  
  J Biol. Chem
  
  Volume: 290 Issue: 10 Pages: 6495-6506
- DOI
  10.1074/jbc.m114.592717
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124, KAKENHI-PROJECT-25293060
[Journal Article] Hydrogen peroxide generated by DUOX1 regulates the expression levels of specific differentiation markers in normal human keratinocyte2014
- Author(s)
  Choi H, Park J, Kim H, Noh M, Ueyama T, Bae Y, Lee TR, Shin DW
- Journal Title
  
  J Dermatol Sci
  
  Volume: 74 Pages: 56-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460340
[Journal Article] Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells,2014
- Author(s)
  Ueyama, T., Sakaguchi, H., Nakamura, T., Goto, A., Morioka, S., Shimizu, A., Nakao, K., Hishikawa, Y., Ninoyu, Y., Kassai, H., Suetsug, J., Koji, T., Fritzsch, B., Yonemura, S., Hisa, Y., Matsuda, M., Aiba, A., and Saito, N.
- Journal Title
  
  J. Cell Science
  
  Volume: 印刷中
- NAID
  120006986582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293060
[Journal Article] Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells2014
- Author(s)
  Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N.
- Journal Title
  
  J Cell Sci.
  
  Volume: 127 Pages: 2040-2052
- DOI
  10.1242/jcs.143602
- NAID
  120006986582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590255, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26291037, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124
[Journal Article] Diacylglycerol kinase gamma regulates antigen-induced mast cell degranulation by mediating Ca2+ influxes2014
- Author(s)
  Sakuma, M., Shirai, Y., Ueyama, T., and Saito, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun,
  
  Volume: 445 Issue: 2 Pages: 340-345
- DOI
  10.1016/j.bbrc.2014.01.197
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26670124
[Journal Article] Diacylglycerol kinase  regulates antigen-induced mast cell degranulation by mediating Ca2+ influxes2014
- Author(s)
  Sakuma M, Shirai Y, Ueyama T, Saito N
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 445 Pages: 340-345
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460340
[Journal Article] RANTES/CCL5 mediated-biological effects depend on the s 1 yndecan-4/PKC signaling pathway2014
- Author(s)
  Maillard L, Saito N, Hlawaty H, Friand V, Suffee N, Chmilewsky F, Haddad O, Laguillier C, Guyot E, Ueyama T, Oudar O, Sutton A, Charnaux N
- Journal Title
  
  Biology Open
  
  Volume: 3 Pages: 995-1004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460340
[Journal Article] RANTES/CCL5 mediated-biological effects depend on the syndecan-4/PKCa signaling pathway2014
- Author(s)
  Maillard, L., Saito, N., Hlawaty, H., Friand, V., Suffee, N., Chmilewsky, F., Haddad, O., Laguillier, C., Guyot, E., Ueyama, T., Oudar, O., Sutton, A., Charnaux, N.
- Journal Title
  
  Biology Open
  
  Volume: 3 Issue: 10 Pages: 995-1004
- DOI
  10.1242/bio.20148227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26670124
[Journal Article] The role of Pak-interacting exchange factor-β phosphorylation at serines 340 and 583 by PKCγ in dopamine release.2014
- Author(s)
  Shirafuji T, Ueyama T, Yoshino K, Takahashi H, Adachi N, Ago Y, Koda K, Nashida T, Hiramatsu N, Matsuda T, Toda T, Sakai N, Saito N.
- Journal Title
  
  J Neurosci
  
  Volume: 34 Issue: 28 Pages: 9268-9280
- DOI
  10.1523/jneurosci.4278-13.2014
- NAID
  120005619641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25293061, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124
[Journal Article] Negative Charges in the Flexible N-Terminal Domain of Rho GDP-Dissociation Inhibitors (RhoGDIs) Regulate the Targeting of the RhoGDI-Rac1 Complex to Membranes2013
- Author(s)
  Ueyama T, Son J, Kobayashi T, Hamada T, Nakamura T, Sakaguchi H, Shirafuji T, Saito N
- Journal Title
  
  J. Immunol.
  
  Volume: 191 Issue: 5 Pages: 2560-2569
- DOI
  10.4049/jimmunol.1300209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060
[Journal Article] Enhanced generation of reactive oxygen species by interferon-γ may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease.2013
- Author(s)
  Yamashita K, Miyoshi T, Arai Y, Mizugishi K, Takaori-Kondo A, Ueyama T
- Journal Title
  
  Int J Hematol
  
  Volume: 97(4) Pages: 505-10
- NAID
  10031168518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590271
[Journal Article] Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes2013
- Author(s)
  Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S
- Journal Title
  
  Mol Biol Cell
  
  Volume: 24 Pages: 1700-1712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590271
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during FcγR-mediated phagocytosis --Mechanism for acquisition of p40phox PI(3)P binding--2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., Son, J-h., Sakaguchi, H., Leto, T., and Saito, N
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 40693-40705
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Direct binding of RalA to ηPKC and its crucial role in morphological change during keratinocyte differentiation2011
- Author(s)
  Shirai Y, Morioka S, Sakuma M, Yoshino Kl, Otsuji C, Sakai N, Kashiwagi K, Chida K, Shirakawa R, Horiuchi H, Nishigori C, Ueyama T, Saito N
- Journal Title
  
  Mol.Biol.Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590271
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma} R-mediated phagocytosis--Mechanism for acquisition of p40phox PI(3)P binding--2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T.,-hyun Son, J-h., Sakaguchi, H., Leto, T., Saito, N.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol.Biol.Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Direct binding of RalA to PKCh and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Cooperation of p40^<phox> with p47^<phox> for Nox2 activation during Fc_γ R-mediated phagocytosis---Mechanism for acquisition of p40^<phox> PI(3)P binding---2011
- Author(s)
  Ueyama T, Nakakita N, Nakamura T, Kobayashi T, Kobayashi T, Son J, Sakuma M, Sakaguchi H, Leto TL, Saito N
- Journal Title
  
  J Biol.Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590271
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma} R-mediated phagocytosis-Mechanism for acquisition of p40phox PI(3) P binding-2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., Son, J-h., Sakaguchi, H., Leto, T., and Saito, N.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 40693-40705
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Direct binding of RalA to PKC and its crucial role in morphological change during keratinocytes differentiation.2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma}R-mediated phagocytosis --Mechanism for acquisition of p40phox PI(3)P binding--"2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., -hyun Son, J-h., Sakaguchi, H., Leto, T., and Saito, N
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] PKC-induced phosphorylation of Orai1 regulates intracellular Ca2+ level via store operated Ca2+ channel2010
- Author(s)
  Kawasaki, T., Ueyama, T., Lange, I., Feske, S. Saito, N.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285(33) Pages: 25720-30
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] PKC-induced phosphorylation of Orai1 regulates intracellular Ca^<2+> level via store operated Ca^<2+> channel2010
- Author(s)
  Kawasaki T, Ueyama T, Lange I, Feske S, Saito N
- Journal Title
  
  J Biol.Chem.
  
  Volume: 285 Pages: 25720-25730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590271
[Journal Article] Duox maturation factors form cell surface complexes with Duox affecting the specificitv of reactive oxvaen species generation2009
- Author(s)
  Morand S, Ueyama T, Tsujibe S, Saito N, Korzeniowska A, Leto TL
- Journal Title
  
  FASEB Journal 23
  
  Pages: 1205-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Ca^<2+> oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (βPKC)2008
- Author(s)
  Ashida, N., Ueyama, T., Rikitake, K., Shirai, Y. Eto, M., Kondoh, T., Kohmura, E., and Saito, N.
- Journal Title
  
  Neurosci. Lett 446
  
  Pages: 123-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Ca2+ oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (・PKC)2008
- Author(s)
  Ashida N, Ueyama T, Rikitake K, Shirai Y, Eto M, Kondoh T, Kohmura E, Saito N
- Journal Title
  
  Neurosci Lett 446
  
  Pages: 123-128
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] 新規アダプター蛋白質(Noxo1, Noxa1)の構造と機能2008
- Author(s)
  上山健彦, 齋藤尚亮
- Journal Title
  
  G.I. Research(先端医学社) 16
  
  Pages: 208-213
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Sequential Binding of Cytosolic Phox Complex to Phagosomes through Regulated Adaptor Proteins : Evaluation Using the Novel Monomeric Kusabira-Green System and Live Imaging of Phagocytosis2008
- Author(s)
  Ueyama, T., 他
- Journal Title
  
  J. Immunol. 181
  
  Pages: 629-640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Sequential Binding of Cytosolic Phox Complex to Phagosomes through Regulated Adaptor Proteins : Evaluation Using the Novel Monomeric Kusabira-Green System and Live Imaging of Phagocytosis2008
- Author(s)
  Ueyama, T., Kusakabe, T., Karasawa, S., Kawasaki, T., Shimizu, A., Son J-H, Shirai, Y., Leto, TL., Miyawaki, A., and Saito N.
- Journal Title
  
  J. Immunol 181
  
  Pages: 629-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Enzymological analysis of mutant protein kinase C gamma causing spinocerebellar ataxia type 14 and dysfunction in Ca^<2+> homeostasis2008
- Author(s)
  Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N
- Journal Title
  
  J of Biological Chemistry 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Regulation of Clathrin Dependent Endocytosis by Diacylglycerol kinaseδ2008
- Author(s)
  Kawasaki, T., Kobayashi, T., Ueyama, T., Shirai, Y. and Saito, N.
- Journal Title
  
  -Importance of Kinase Activity and Binding to AP2α-Biochem. J 409
  
  Pages: 471-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Regulation of clathrin dependent endocytosis by diacylglycerol kinase delta-importance of kinase activity and binding to AP2alpha.2008
- Author(s)
  Kawasaki, Kobayashi, Ueyama, Shirai, Saito
- Journal Title
  
  Biochemical Journal 409
  
  Pages: 471-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Ca^<2+> oscillation induced by P2Y2 receptor activation and its regulation by a neuron-spacific subtype of PKC (γPKC)2008
- Author(s)
  Ashida N, Ueyama T, Rikitake K, Shirai Y, Eto M, Kondoh T, Kohmura E, Saito N
- Journal Title
  
  Neuroscience Letters 446
  
  Pages: 123-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Sequential binding of cytosolic phox proteins to phagosomes through regulated adaptor proteins: evaluation using the novel monomeric Kusabira-Green system and live imaging of phagocytosis2008
- Author(s)
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N
- Journal Title
  
  J Immunol. 181
  
  Pages: 629-640
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Enzymological analysis of mutant protein kinase C gamma causing spinocerebeliar ataxia type 14 and dysfunction in Ca^<2+> homeostasis.2008
- Author(s)
  Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N
- Journal Title
  
  j of Biological Chemistry 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Regulation of clathrin dependent endocytosis by diacylglycerol kinase delta-importance of kinase activity and binding to AP2alpha2008
- Author(s)
  Kawasaki T, Kobayashi T, Ueyama T, Shirai Y, Saito N
- Journal Title
  
  Biochem J 409
  
  Pages: 471-479
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Enzymological analysis of mutant protein kinase C gamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis2008
- Author(s)
  Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N.
- Journal Title
  
  J Biol Chem, 283
  
  Pages: 19854-19863
- Data Source
  KAKENHI-PROJECT-19590278
[Journal Article] Enzymological analysis of mutant protein kinase Cγ causing spinocerebellar ataxia type 14 and its dysfunction in Ca^<2+> homeostasis2008
- Author(s)
  Adachi, N., Kobayashi, T., Takahashi, H., Kawasaki, T., Shirai, Y., Ueyama, T., Matsuda, T., Seki, T., Sakai, N. and Saito N.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] A regulated adaptor function of p40^<phox>: distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>2007
- Author(s)
  Ueyama T, et al
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 441-454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] A regulated adaptor function of p40^<phox> : distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>.2007
- Author(s)
  Ueyama T
- Journal Title
  
  Mol. Biol. Cell 18,2
  
  Pages: 441-454
- Data Source
  KAKENHI-PROJECT-17790189
[Journal Article] A regulated adaptor function of p4O^<phox> : distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>.2007
- Author(s)
  Ueyama T, et al.
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 441-454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Subcellular localization and function of alternatively spliced Noxo1 isoforms.2007
- Author(s)
  Ueyama T
- Journal Title
  
  Free Radical Biol. Med. 42,2
  
  Pages: 180-190
- NAID
  120000942003
- Data Source
  KAKENHI-PROJECT-17790189
[Journal Article] A regulated adaptor function fof p40^<phox>: distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>.2007
- Author(s)
  Ueyama T, et. al.
- Journal Title
  
  Mol. Biol. Cell, 18
  
  Pages: 441-454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18053016
[Journal Article] A regulated adaptor function of p40^<phox> : distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>2007
- Author(s)
  Ueyama T, 他
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 441-454
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] A regulated adaptor function of p40^<phox>. distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>2007
- Author(s)
  Ueyama T, 他
- Journal Title
  
  Mol. Biol. Cell. 18
  
  Pages: 441-454
- Data Source
  KAKENHI-PROJECT-18053016
[Journal Article] Subcellular localization and function of alternatively spliced Noxo1 isoforms.2007
- Author(s)
  Ueyama T 他
- Journal Title
  
  Free Radical Biol. Med 42
  
  Pages: 180-190
- NAID
  120000942003
- Data Source
  KAKENHI-PROJECT-18053016
[Journal Article] Subcellular localization and function of alternatively spliced Noxo1 isoforms.2007
- Author(s)
  Ueyama T. et al.
- Journal Title
  
  Free Radical Biol. Med. 42
  
  Pages: 180-190
- NAID
  120000942003
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Subcellular localization and function of alternatively spliced Noxo1 isoforms.2007
- Author(s)
  Ueyama T 他
- Journal Title
  
  Free Radical Biol. Med 42
  
  Pages: 180-190
- NAID
  120000942003
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] A regulated adaptor function of p40^<phox> distinct p67^<phox> membrane targeting by p40^<phox> and by p47^<phox>.2007
- Author(s)
  Ueyama T, 他
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 441-454
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Involvement of Rac1 in activation of multicomponent Nox1 and Nox3-based NADPH oxidases.2006
- Author(s)
  Ueyama T
- Journal Title
  
  Mol. Cell. Biol. 26,6
  
  Pages: 2160-2174
- NAID
  120000942467
- Data Source
  KAKENHI-PROJECT-17790189
[Journal Article] Involvement of Rac1 in activation of multicomponent Nox1 and Nox3-based NADPH oxidases2006
- Author(s)
  Ueyama T
- Journal Title
  
  Molecular and Cellular Biology 26・6
  
  Pages: 2160-2174
- NAID
  120000942467
- Data Source
  KAKENHI-PROJECT-17790189
[Journal Article] Isoform-specific Membrane Targeting Mechanism of Rac During FcγR-mediated Phagocytosis.-Positive charge-dependent and independent targeting mechanism of Rac to the phagosome-2005
- Author(s)
  Ueyama, T.他
- Journal Title
  
  J.Immunol. 175
  
  Pages: 2381-2390
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Isoform-specific Membrane Targeting Mechanism of Rac During FcgR-mediated Phagocytosis.2005
- Author(s)
  Ueyama T
- Journal Title
  
  J of Immunology 175・4
  
  Pages: 2381-2390
- Data Source
  KAKENHI-PROJECT-17790189
[Journal Article] Isoform-specific Membrane Targeting Mechanism of Rac During FcγR-mediated Phagocytosis.- Positive charge-dependent and independent targeting mechanism of Rac to the phagosome-2005
- Author(s)
  Ueyama, T., 他
- Journal Title
  
  J. Immunol. 175
  
  Pages: 2381-2390
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Isoform-specific Membrane Targeting Mechanism of Rac During FcγR-mediated Phagocytosis--Positive charge-dependent and independent targeting mechanism of Rac to the phagosome-2005
- Author(s)
  Ueyama, T. et al.
- Journal Title
  
  J. Immunol. 175
  
  Pages: 2381-2390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Isoform-specific Membrane Targeting Mechanism of Rac During FcgR-mediated Phagocylosis.2005
- Author(s)
  Ueyama T
- Journal Title
  
  J Immunol 175,4
  
  Pages: 2381-2390
- Data Source
  KAKENHI-PROJECT-17790189
[Presentation] Sensorineural hearing loss: challenges for therapy development based on its mechanisms2022
- Author(s)
  上山健彦
- Organizer
  第8回ニューロサイエンスネットワークシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H02672
[Presentation] Acquired hearing loss induced by ROS and challenges for therapy development based on its mechanism2022
- Author(s)
  上山健彦
- Organizer
  日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02672
[Presentation] 活性酸素産生酵素Nox3のマウス脳内発現分布に関する解析2021
- Author(s)
  鈴木俊章　山口恭子　上山健彦
- Organizer
  第140回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19K22472
[Presentation] 細胞骨格異常に起因する新規の症候群性遺伝性感音難聴: 糖鎖修飾欠損型筋ジストロフィーに合併する末梢蝸牛神経の髄鞘化障害による聴覚異常2020
- Author(s)
  上山健彦
- Organizer
  第30回日本耳科学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22472
[Presentation] ROSによる聴覚伝達障害の発症メカニズム解明2020
- Author(s)
  陳　林　毛利宏明　齋藤尚亮　上山健彦
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] DFNA1疾患モデルマウスを用いたDIA1分子の局在と病態メカニズムの解2019
- Author(s)
  二之湯弦、坂口博史、陳林、毛利宏明、齋藤尚亮、上山健彦
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] 活性酸素種（ROS）過剰発現モデルマウスにおける聴覚機能解析と聴覚保護因子の検索2019
- Author(s)
  森岡　繁文、坂口　博史、山口　太郎、二之湯　弦、毛利　宏明、中村　高志、久　育男、荻田　喜代一、齋藤　尚亮、上山　健彦
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] 遺伝子改変マウスからの疾患病態解明と治療法開発戦略へのフィードバック2019
- Author(s)
  上山　健彦
- Organizer
  第60回日本組織細胞化学会総会・学術集会および第13回日中合同組織細胞化学セミナー
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] 難聴を生み出す活性酸素発生源細胞の同定とその機能・障害メカニズムの解明2019
- Author(s)
  毛利宏明、二之湯弦、坂口博史、齋藤尚亮、上山健彦
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] Cysteine String Protein alpha (CSPa)Ser34特異的リン酸化抗体の作製と機能解析2019
- Author(s)
  白藤俊彦, 上山健彦, 足立直子, 齋藤尚亮
- Organizer
  第60回日本組織細胞化学会総会
- Data Source
  KAKENHI-PROJECT-18K06700
[Presentation] 遺伝子改変マウスからの疾患病態解明と治療法開発戦略へのフィードバック2019
- Author(s)
  上山　健彦
- Organizer
  第60回日本組織細胞化学会総会・学術集会および第13回日中合同組織細胞化学セミナー
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22472
[Presentation] The molecular mechanism of hearing loss caused by a novel DIA1 mutant (R1204X)2017
- Author(s)
  Yuzuru Ninoyu, Shin-ichiro Kitajiri, Takushi Miyoshi, Dean Thumkeo, Hirofumi Sakaguchi, Naoki Watanabe, Shin-ichi Usami, Naoaki Saito, Takehiko Ueyama
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460340
[Presentation] 脳・脊髄損傷後修復時のアストロサイトにおける新規シグナリング2017
- Author(s)
  上山健彦
- Organizer
  第５８回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04042
[Presentation] Analysis of hearing loss causing from failed maintenance of auditory hair’s integrity2016
- Author(s)
  Takehiko Ueyama
- Organizer
  第８９回日本薬理学会年会、シンポジウム
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26460340
[Presentation] 脊髄小脳変性症14型におけるPKCのアミロイド様構造体の形成と疾患への関与2015
- Author(s)
  足立直子、高橋英之、白藤俊彦、上山健彦、Michele, Vendruscolo., 入江一浩、平井宏和、酒井規雄、齋藤尚亮
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 脊髄小脳変性症14型におけるPKCのアミロイド様構造体の形成と疾患への関与2015
- Author(s)
  足立直子、高橋英之、白藤俊彦、上山健彦、Michele, Vendruscolo., 入江一浩、平井宏和、酒井規雄、齋藤尚亮
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] Cde-42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells2014
- Author(s)
  Ueyama, T. and Saito, N.
- Organizer
  Joint Workshop between University Catholic Louvain and Kobe University
- Place of Presentation
  Brussels, Belgium
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 黒質線条体系におけるPKC・の基質の解析:ドパミン遊離における・PI・リン酸化の役割2013
- Author(s)
  白藤俊彦, 上山健彦, 吉野健一, 足立直子,高橋英之, 吾郷由希夫, 松田敏夫,齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] Duox の活性酸素産生機構2013
- Author(s)
  佐久間恵、上山健彦、ヒン田猛、齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡(口頭発表・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 黒質線条体系におけるPKCγの基質の解析：β2PIXリン酸化のドパミン遊離への役割2013
- Author(s)
  白藤俊彦、上山健彦、吉野健一、足立直子、高橋英之、香田健、平松直樹、吾郷由希夫、松田敏夫、酒井　規雄、齋藤　尚亮
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 黒質線条体系における PKCγの基質の解析:ドパミン遊離におけるβPIX リン酸化の役割2013
- Author(s)
  白藤俊彦、上山健彦、吉野健一、足立直子、高橋英之、吾郷由希夫、松田敏夫、齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡(口頭発表・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Duoxの活性酸素産生機構2013
- Author(s)
  佐久間　恵、上山　健彦、濵田　猛、齋藤　尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Duox と Duoxa の H2O2 産生に重要な領域の同定2013
- Author(s)
  佐久間恵,上山健彦,浜田猛,齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] 中枢神経損傷とRho family GTPases (CNS injury and Rho family GTPases)2012
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(口頭発表、英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Glial functions of Rho-family small GTPases during cerebellar development and after CNS injury2012
- Author(s)
  Ueyama,T., Kondoh T., Kohta M., Kohmura,E., Hayashibe,M., Nakamura,T.,
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Involvment of PKCgamma in neurodegenerative disease2012
- Author(s)
  Saito, N., Takahashi, H., Shirafuji, T., Adachi, N., Danno, S., Ueyama, T., Seki, T. and Sakai,N
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都(ポスター・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Involvment of PKCgamma in neurodegenerative disease2012
- Author(s)
  Saito, N., Takahashi, H., Shirafuji, T., Adachi, N., Danno, S., Ueyama, T.,
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] ジアシルグリセロールキナーゼのヒスタミン分泌制御における役割2012
- Author(s)
  佐久間恵、白井康仁、上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(ポスター発表、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 中枢神経損傷と Rho family GTPases (CNS injury and Rho family GTPases)2012
- Author(s)
  上山健彦
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] Glial functions of Rho-family small GTPases during cerebellar development and after CNS injury2012
- Author(s)
  Ueyama,T., Kondoh T., Kohta M., Kohmura,E., Hayashibe,M., Nakamura,T., Sakahara,M., Kassai,H., Nakao,K., Aiba,A. and Saito,N.
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都(ポスター・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 中枢神経損傷とRho family GTPases2012
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  (京都府)国立京都国際会館
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 中枢神経損傷とRho family GTPases (CNS injury and Rho family GTPases)2012
- Author(s)
  上山健彦
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(招待講演)
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] 部位特異的 KO マウスを用いた低分子量 G タンパク質の組織学的機能解析2011
- Author(s)
  上山健彦
- Organizer
  日本組織細胞化学会年会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] Translocation/dissociation/activation mechanisms of Rac-RhoGDI complex on membranes2011
- Author(s)
  Takehiko Ueyama
- Organizer
  2011 International Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] Translocation/dissociation/activation mechanisms of Rac-RhoGDI complex on membranes2011
- Author(s)
  Takehiko Ueyama
- Organizer
  International Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] Regulatory mechanisms of Rac activation by RhoGDI2011
- Author(s)
  Takehiko Ueyama
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] 部位特異的KOマウスを用いた低分子量Gタンパク質の組織学的機能解析2011
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  日本組織細胞化学会年会
- Place of Presentation
  金沢(招待講演、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Rac-RhoGDI複合体の解離・活性化メカニズム2010
- Author(s)
  上山健彦
- Organizer
  生理学研究所研究会「貪食細胞機能のイメージング」
- Place of Presentation
  岡崎カンファレンスセンター(愛知県)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-20056022
[Presentation] Translocation/dissociation/activation mechanisms of Rac-RhoGDI complex on membranes2010
- Author(s)
  Takehiko Ueyama
- Organizer
  Gordon Research Cofference
- Place of Presentation
  Les Diablerets, Switerland
- Data Source
  KAKENHI-PROJECT-22590271
[Presentation] マウス初代培養表皮細胞におけるRac3のRac1代償機能2009
- Author(s)
  清水彩、上山健彦、坂原瑞穂、饗場篤、齋藤尚亮
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Sequential targeting of cytosolic phox proteins to phagosomes through regulated adaptor proteins during Fc□R-mediated phagocytosis2008
- Author(s)
  Ueyama,T., Kusakabe,T., Karasawa,S., Kawasaki,T., Shimizu,A., Son,eong-hyun., Leto L.Thomas
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green (mKG) system and live imaging of phagocytosis2008
- Author(s)
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N
- Organizer
  Gordon Research Conferences (NADPH oxidase)
- Place of Presentation
  Colby-Sawyer College, Laconia, NH, USA
- Data Source
  KAKENHI-PROJECT-20056022
[Presentation] Nox2 活性化時におけるphox蛋白複合体の食胞膜へのターゲティング機構2008
- Author(s)
  上山健彦, 他8名
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシヒィコ横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19590278
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins2008
- Author(s)
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N
- Organizer
  Gordon Research Conferences (NADPH oxidase)
- Place of Presentation
  Colby-Sawyer College, NH, USA
- Data Source
  KAKENHI-PROJECT-19590278
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green(mKG) system and liveimaging of phagocytosis.2008
- Author(s)
  Ueyama, T., 他
- Organizer
  Gordon Research Conference
- Place of Presentation
  ボストン(米国)
- Year and Date
  2008-06-04
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green(mKG)system and liveimaging of phagocytosis2008
- Author(s)
  Ueyama,T., Kusakabe,T., Karasawa,S., Kawasaki,T., Shimizu,A., Son, Jeong-hyun., Leto,L.Thomas., Miyawaki,A., Saito,N.
- Organizer
  Gordon Research Conference
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] NADPH oxidaseファミリーの活性化機構とその生理機能2008
- Author(s)
  上山健彦
- Organizer
  第3回グローバルCOE研究討論会
- Place of Presentation
  淡路島(兵庫)
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Nox2活性化時におけるphox蛋白複合体の食胞膜へのターゲティング機構2008
- Author(s)
  上山健彦, 他8名
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  バシフィコ横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19590278
[Presentation] Differential regulation of dual oxidase 1 by dual activator 1 splicing variants2008
- Author(s)
  Tsujibe,S., Ueyama,T., Shirai,Y., Leto L. Thomas., Saito,N.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulateda daptor proteins : evaluation using the novel monomeric Kusabira-Green (mKG) system and live imaging of phagocytosis.2008
- Author(s)
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, SonJ, Leto TL, Miyawaki A, Saito N
- Organizer
  Gordon Research Conferences (NADPH oxidase)
- Place of Presentation
  Colby-Sawyer College, Laconia, NH, USA
- Data Source
  KAKENHI-PROJECT-19590278
[Presentation] Clarification of regulatory mechanism of Orail(SOCs)by PKC2007
- Author(s)
  Kawasaki,T., Ueyama,T., Shirai,Y., Saito, N.
- Organizer
  14^<th> Congress of Ca2+ binding proteins & Ca2+ function in health & disease
- Place of Presentation
  La Palma Spain
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] A regulated adaptor function of p40phox : Intramolecular interaction (PX-PB1 domain)within p40phox2007
- Author(s)
  Ueyama,T., Tatsuno,T., Kawasaki,T., Thomas L.Leto., Saito, N.
- Organizer
  Gordon Research Conference
- Place of Presentation
  ロードアイランド
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] A regulated adaptor function of p40phox: Intramolecular interaction (PX-PB1 domain) within p40phox2007
- Author(s)
  Ueyama T, Tatsuno T, Kawasaki T, Leto TL, Saito N
- Organizer
  Gordon Research Conferences (Phagocytes)
- Place of Presentation
  Bryant University, Smithfield, RI, USA
- Data Source
  KAKENHI-PROJECT-19590278
[Presentation] P2Y受容体を介するγPKCのオシレーション機構の解明2006
- Author(s)
  芦田典明、上山健彦、力武恭子、白井康仁、衛藤三佳、近藤威、甲村英二、齋藤尚亮
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2006-06-20
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] RalAはηPKCによるケラチノサイトの扁平化に必須である。2006
- Author(s)
  白井康仁、盛岡祥子、大辻千裕、吉野健一、酒井規雄、上山健彦、齋藤尚亮
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2006-06-20
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] ・Maintenance of stereocillia and apical junctional complexes by Cdc42 in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi,H., Nakamura, T., Goto, A., Morioka, S., Fritzsch, B., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] Cdc42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi, H., Goto, A., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  The 37th Naito Conference,
- Place of Presentation
  北海道ニセコ
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] 中枢神経損傷とRho family GTPases
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Cdc42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi, H., Goto, A., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  The 37th Naito Conference
- Place of Presentation
  北海道ニセコ
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25293060

1. SAITO Naoaki (60178499)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. SAKAGUCHI Hirofumi (00515223)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. SHIRAI Yasuhito (60263399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. ADACHI Naoko (70604510)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
5. SHIRAFUJI Toshihiko (30595765)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. KUSUNOKI Masato (50192026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 中村高志 (80724179)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 瀧正勝 (30453111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HISHIKAWA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. TANAKA SHIGERU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KOBAYASHI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 斎藤尚亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 56 results
13. 酒井規雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. チョウジョウフナランツオツク

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 秀和泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 東田千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 内匠透

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 戸田達史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UEYAMA TAKEHIKO 上山 健彦

UEYAMA Takehiko 上山 健彦

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活性酸素産生酵素NOX3の発現制御機序解明による後天性及び片側性難聴の治療法開発Principal Investigator

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Elucidation of acquired SNHL mechanism caused from Nox3-derived ROS and beyondPrincipal Investigator

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Challenge for establishing the criteria of laterality-based diseases in hearing and visionPrincipal Investigator

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Mechanism clarification of new symptoms in DFNA1 causing from constitutively active DAI1 mutantsPrincipal Investigator

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Roles of Rho-family small GTPases in establishment and maintenance for hearing and balancingPrincipal Investigator

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Roles of small GTPases and ROS in functions anddiseases of inner earPrincipal Investigator

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UEYAMA TAKEHIKO 上山健彦

UEYAMA Takehiko 上山健彦