abe hiroshi 阿部洋

… Alternative Names

ABE Hiroshi 阿部洋

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Researcher Number	80415067
Other IDs
Affiliation (Current)	2025: 名古屋大学, 理学研究科, 教授 2025: 名古屋大学, 糖鎖生命コア研究所, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 名古屋大学, 理学研究科, 教授 2016 – 2019: 名古屋大学, 理学研究科, 教授 2015: 名古屋大学, 理学(系)研究科(研究院), 教授 2013 – 2014: 北海道大学, 薬学研究科(研究院), 准教授 2009 – 2012: The Institute of Physical and Chemical Research, 伊藤ナノ医工学研究室, 専任研究員 2006 – 2008: 独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 研究員 2007: The Institute of Physical and Chemical Research, 伊藤ナノ医工学研究室, 研究員
Review Section/Research Field	Principal Investigator Chemical biology / Biofunction/Bioprocess / Chemistry related to living body / Broad Section E / Bio-related chemistry / Transition State Control Except Principal Investigator Medium-sized Section 62:Applied informatics and related fields / Medium-sized Section 52:General internal medicine and related fields / Basic Section 90110:Biomedical engineering-related / Medium-sized Section 90:Biomedical engineering and related fields … More / System genome science / Drug development chemistry / Biofunction/Bioprocess / Living organism molecular science / Biomedical engineering/Biological material science Less
Keywords	Principal Investigator RNA / 蛍光 / 化学反応 / 細胞 / RNA干渉 / 免疫応答 / 環状 / タンパク質 / リボソーム / 翻訳 … More / プローブ / DNA / イメージング / 検出 / 遺伝子 / 増幅 / 蛍光発生化合物 / ナノサイズ / ナノバイオ / 翻訳反応 / ライゲーション / 生体内有機化学 / ビルドアップ / 細胞膜透過性 / 核酸医薬 / 中分子 / ナノテクノロジー / 光反応 / デリバリー / siRNA / 触媒 / 遷移状態 / センサー / 鋳型反応 / RNAプローブ / 触媒回転数 / 核酸鋳型反応 / 蛍光プローブ / 核酸プローブ / グルタチオン / グルタチオントランスフェラーゼ / 生理活性 / 酵素 / 終わりのない回転式翻訳 / 原核生物 / 環状RNA / タンパク質合成 / mRNA / 単離 / 還元反応 / miRNA / 未分化 / フローサイトメーター / 分離 / 核酸連結反応 / 遺伝子検出 / 試験管内進化法 / タンパク質検出 / 消光 / アプタマー / 蛋白質 … More Except Principal Investigator 翻訳効率 / RNA修飾塩基 / RNA２次構造 / 修飾塩基 / 非天然アミノ酸 / 神経変性疾患 / 核酸 / 配列設計 / mRNA / イオントフォレシス / mRNA翻訳 / 薬物送達システム / ワクチン / RNA工学 / ペプチド / mRNAワクチン / 核酸医薬 / mRNA工学 / 中分子医薬 / mRNA医薬 / エピトランスクリプトーム解析 / エピとランスクリプトーム解析 / ＲＮＡ2次構造 / エヒトランスプリクトーム / RNA2次構造 / エネルギーパラメタ / 分子動力学 / バイオインフォマティクス / エピトランスクリプトーム / RNAi創薬 / 化学合成 / DNAデバイス / 核酸創薬 / 進化分子工学 / アルドール縮合 / ミスアシル化tRNA / ペプチド触媒 / mRNAディスプレイ / 分子進化工学 / テロメア / ポリエチレングリコール / 構造 / ルミノール反応 / 触媒 / 有機溶媒 / DNA / G-カルテット / キメラタンパク質 / ミスアシル化tRNA法 / ケミカルライゲーション法 / リボソーム・ディスプレイ / タンパク質工学 / 成長因子 / 表面処理 / バイオマテリアル Less

新規翻訳誘導技術を用いた環状RNAの分子設計と応用Principal Investigator
- Principal Investigator
  
  阿部洋
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section E
- Research Institution
  Nagoya University
送達担体を用いないmRNAの新規体内送達技術による革新的疾患治療
- Principal Investigator
  
  小暮健太朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokushima
化学修飾を含むmRNA配列設計の基盤技術
- Principal Investigator
  
  浅井潔
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  The University of Tokyo
Development of next-generation antisense therapeutics for neurological diseases
- Principal Investigator
  
  佐橋健太郎
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Development and therapeutic application of short mRNA therapeutics based on mRNA engineering
- Principal Investigator
  
  内田智士
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University
  Kyoto Prefectural University of Medicine
修飾塩基を持つRNAの情報解析基盤技術の開発
- Principal Investigator
  
  浅井潔
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  The University of Tokyo
Medium molecularization strategy of high molecular weight RNA medicinePrincipal Investigator
- Principal Investigator
  
  阿部洋
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Nagoya University
Improvement of catalytic turnover based on transition state control of oligonucleotide template chemical reactionPrincipal Investigator
- Principal Investigator
  
  Abe Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Transition State Control
- Research Institution
  Nagoya University
RNA informatics for epi-transcriptome analysis
- Principal Investigator
  
  Asai Kiyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  System genome science
- Research Institution
  The University of Tokyo
Protein synthesis using circular RNAPrincipal Investigator
- Principal Investigator
  
  Abe Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Nagoya University
Development of molecular probe for GSTPrincipal Investigator
- Principal Investigator
  
  Abe Hiroshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Nagoya University
Investigation of practical anticancer strategy based on chemically synthesized iRed/iPed
- Principal Investigator
  
  MINAKAWA Noriaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokushima
Development of RNA medicine based on nano-structured design and templated reactionPrincipal Investigator
- Principal Investigator
  
  ABE HIROSHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Nagoya University
  Hokkaido University
Screening of peptide catalyst by chemically extended molecular evlutionary engineering
- Principal Investigator
  
  ITO Yoshihiro
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research
Analysis and application of new translation systemPrincipal Investigator
- Principal Investigator
  
  ABE Hiroshi
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research
Cell selection based on genetic signalPrincipal Investigator
- Principal Investigator
  
  ABE Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research
Chemical probe for amplification of genetic signalPrincipal Investigator
- Principal Investigator
  
  ABE Hiroshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research
Creation of growth factors binding to metal or ceramic for and their medical applications
- Principal Investigator
  
  ITO Yoshihiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The Institute of Physical and Chemical Research
有機溶媒中での試験管内進化法による触媒探索
- Principal Investigator
  
  伊藤嘉浩
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
細胞内蛋白質を可視化できるバイオプローブの開発Principal Investigator
- Principal Investigator
  
  阿部洋
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 化学　Vol.74　No.82019
- Author(s)
  阿部洋, 木村康明, Shu Zhaoma
- Total Pages
  4
- Publisher
  化学同人
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Book] Methods in Molecular Biology 17242018
- Author(s)
  Naoko Abe, Ayumi Kodama, Hiroshi Abe
- Publisher
  Humana Press
- ISBN
  9781493975624
- Data Source
  KAKENHI-PROJECT-16H04178
[Book] PEGylated Antibodies and DNA in Organic Media and Genetic PEGylation"in"Green Polymer 2.!!ed. by H. N. Chen and R. A. Gross2013
- Author(s)
  Seiichi Tada, Hiroshi Abe, and Yoshihiro Ito
- Publisher
  ACS (accepted)
- Data Source
  KAKENHI-PROJECT-24656510
[Book] 「生細胞内RNA検出のための化学反応プローブ」「難培養微生物研究の最新技術II～ゲノム解析を中心とした最前線と将来展望～」2010
- Author(s)
  古川和寛、阿部洋、伊藤嘉浩、常田聡
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22686077
[Book] 難培養微生物研究の最新技術II～ゲノム解析を中心とした最前線と将来展望2010
- Author(s)
  古川和寛、阿部洋、伊藤嘉浩、常田聡
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22686077
[Book] 細胞機能制御高分子と再生医療高分子2009
- Author(s)
  伊藤嘉浩、北嶋隆、阿部洋
- Data Source
  KAKENHI-PROJECT-20750146
[Journal Article] An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery2023
- Author(s)
  Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 3 Pages: 250-256
- DOI
  10.1248/cpb.c22-00852
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures2023
- Author(s)
  Masahito Inagaki, Naoko Abe, Zhenmin Li, Yuko Nakashima, Susit Acharyya, Kazuya Ogawa, Daisuke Kawaguchi, Haruka Hiraoka, Ayaka Banno, Zheyu Meng, Mizuki Tada, Tatsuma Ishida, Pingxue Lyu, Kengo Kokubo, Hirotaka Murase, Fumitaka Hashiya, Yasuaki Kimura, Satoshi Uchida & Hiroshi Abe
- Journal Title
  
  nature communications
  
  Volume: 14 Issue: 1 Pages: 2657-2657
- DOI
  10.1038/s41467-023-38244-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21J15693, KAKENHI-PROJECT-21H04962
[Journal Article] Complete Chemical Synthesis of Minimal Messenger RNA by Efficient Chemical Capping Reaction2022
- Author(s)
  Naoko Abe, Akihiro Imaeda, Masahito Inagaki, Zhenmin Li, Daisuke Kawaguchi, Kaoru Onda, Yuko Nakashima, Satoshi Uchida, Fumitaka Hashiya, Yasuaki Kimura, Hiroshi Abe
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 6 Pages: 1308-1314
- DOI
  10.1021/acschembio.1c00996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] A helix foldamer oligopeptide improves intracellular stability and prolongs protein expression of the delivered mRNA2021
- Author(s)
  S. Uchida, Y. Yamaberi, M. Tanaka, M. Oba
- Journal Title
  
  Nanoscale
  
  Volume: 13 Issue: 45 Pages: 18941-18946
- DOI
  10.1039/d1nr03600a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Intracellular Delivery of Antisense DNA and siRNA with Amino Groups Masked with Disulfide Units2020
- Author(s)
  Shu Zhaoma、Ota Azumi、Takayama Yukiya、Katsurada Yuri、Kusamori Kosuke、Abe Naoko、Nakamoto Kosuke、Tomoike Fumiaki、Tada Seiichi、Ito Yoshihiro、Nishikawa Makiya、Kimura Yasuaki、Abe Hiroshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 2 Pages: 129-132
- DOI
  10.1248/cpb.c19-00811
- NAID
  130007793432
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-02-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15713, KAKENHI-PUBLICLY-18H04398, KAKENHI-PROJECT-18K14357
[Journal Article] Quantification of native mRNA dynamics in living neurons using fluorescence correlation spectroscopy and reduction-triggered fluorescent probes2020
- Author(s)
  Fujita Hirotaka、Oikawa Ryota、Hayakawa Mayu、Tomoike Fumiaki、Kimura Yasuaki、Okuno Hiroyuki、Hatashita Yoshiki、Fiallos Oliveros Carolina、Bito Haruhiko、Ohshima Toshio、Tsuneda Satoshi、Abe Hiroshi、Inoue Takafumi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Issue: 23 Pages: 7923-7940
- DOI
  10.1074/jbc.ra119.010921
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Journal Article] Intracellular build-up RNAi with single-strand circular RNAs as siRNA precursors2020
- Author(s)
  Kimura Yasuaki、Shu Zhaoma、Ito Mika、Abe Naoko、Nakamoto Kosuke、Tomoike Fumiaki、Shuto Satoshi、Ito Yoshihiro、Abe Hiroshi
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Issue: 3 Pages: 466-469
- DOI
  10.1039/c9cc04872c
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15713, KAKENHI-PUBLICLY-18H04398, KAKENHI-PROJECT-18K14357, KAKENHI-PROJECT-19H01014
[Journal Article] Translational control by secondary-structure formation in mRNA in a eukaryotic system2020
- Author(s)
  Daisuke Kawaguchi, Saaya Shimizu, Naoko Abe, Fumitaka Hashiya, Fumiaki Tomoike,Yasuaki Kimura, Hiroshi Abe
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 39 Issue: 1-3 Pages: 195-203
- DOI
  10.1080/15257770.2019.1671593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14357, KAKENHI-PROJECT-19K15713, KAKENHI-PUBLICLY-18H04398
[Journal Article] Chemically synthesized circular RNAs with phosphoramidate linkages enable rolling circle translation2020
- Author(s)
  Nakamoto Kosuke、Abe Naoko、Tsuji Genichiro、Kimura Yasuaki、Tomoike Fumiaki、Shimizu Yoshihiro、Abe Hiroshi
- Journal Title
  
  Chemical Communications
  
  Volume: - Issue: 46 Pages: 6217-6220
- DOI
  10.1039/d0cc02140g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398, KAKENHI-PROJECT-18K14357, KAKENHI-PROJECT-19K15713
[Journal Article] Synthesis and Biological Evaluation of NMDI-14 Derivatives as anti-Mesothelioma Agents2020
- Author(s)
  Hong Nhung Nguyen, Koya Suzuki, Yasuaki Kimura, Takatsugu Hirokawa, Yuko Murakami-Tonami, and Hiroshi Abe
- Journal Title
  
  Heterocycles
  
  Volume: 100 Issue: 2 Pages: 253-266
- DOI
  10.3987/com-19-14191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06979, KAKENHI-PROJECT-19K16809, KAKENHI-PUBLICLY-18H04398
[Journal Article] Disulfide-Unit Conjugation Enables Ultrafast Cytosolic Internalization of Antisense DNA and siRNA2019
- Author(s)
  Shu Zhaoma、Tanaka Iku、Ota Azumi、Fushihara Daichi、Abe Naoko、Kawaguchi Saki、Nakamoto Kosuke、Tomoike Fumiaki、Tada Seiichi、Ito Yoshihiro、Kimura Yasuaki、Abe Hiroshi
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 印刷中 Issue: 20 Pages: 6611-6615
- DOI
  10.1002/anie.201900993
- NAID
  130007841763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0052, KAKENHI-PROJECT-17K15479, KAKENHI-PROJECT-18K14357, KAKENHI-PUBLICLY-18H04398
[Journal Article] A robust model for quantitative prediction of the silencing efficacy of wild-type and A-to-I edited miRNAs2019
- Author(s)
  Tian Shen、Terai Goro、Kobayashi Yoshiaki、Kimura Yasuaki、Abe Hiroshi、Asai Kiyoshi、Ui-Tei Kumiko
- Journal Title
  
  RNA Biology
  
  Volume: 17 Issue: 2 Pages: 264-280
- DOI
  10.1080/15476286.2019.1678364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04398, KAKENHI-PROJECT-16H02484, KAKENHI-PROJECT-16H06279
[Journal Article] N6-methyl adenosine in siRNA evades immune response without reducing RNAi activity2019
- Author(s)
  Akihiro Imaeda, Fumiaki Tomoike, Mayu Hayakawa, Kosuke Nakamoto, Yasuaki Kimura, Naoko Abe, Hiroshi Abe
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 38 Issue: 12 Pages: 972-979
- DOI
  10.1080/15257770.2019.1641205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14357, KAKENHI-PROJECT-19K15713, KAKENHI-PUBLICLY-18H04398
[Journal Article] A Covalent Inhibitor for Glutathione S‐Transferase Pi (GSTP1‐1) in Human Cells2019
- Author(s)
  Shishido Yuko、Tomoike Fumiaki、Kuwata Keiko、Fujikawa Haruka、Sekido Yoshitaka、Murakami‐Tonami Yuko、Kameda Tomoshi、Abe Naoko、Kimura Yasuaki、Shuto Satoshi、Abe Hiroshi
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 7 Pages: 900-905
- DOI
  10.1002/cbic.201800671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14356, KAKENHI-PROJECT-17K15479, KAKENHI-PUBLICLY-18H04398, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-18K06979, KAKENHI-PROJECT-15K08325
[Journal Article] Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation2018
- Author(s)
  Onizuka Kazumitsu、Miyashita Takuya、Chikuni Tomoko、Ozawa Mamiko、Abe Hiroshi、Nagatsugi Fumi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 46 Issue: 17 Pages: 8710-8719
- DOI
  10.1093/nar/gky744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-16KT0052, KAKENHI-PROJECT-16K08153
[Journal Article] Chemical ligation of oligonucleotides using an electrophilic phosphorothioester2017
- Author(s)
  Maruyama Hideto、Oikawa Ryota、Hayakawa Mayu、Takamori Shono、Kimura Yasuaki、Abe Naoko、Tsuji Genichiro、Matsuda Akira、Shuto Satoshi、Ito Yoshihiro、Abe Hiroshi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 45 Issue: 12 Pages: 7042-7048
- DOI
  10.1093/nar/gkx459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21091, KAKENHI-PROJECT-16H02484
[Journal Article] Diastereoselective Synthesis of 6" (Z)- and 6" (E) Fluoro Analogues of Anti-hepatitis B Virus Agent Entecavir and Its Evaluation of the Activity and Toxicity Profile of the Diastereomers2016
- Author(s)
  Hiroki Kumamoto, Misato Fukano, Tomohiko Nakano, Keito Iwagami, Chiaki Takeyama, Satoru Kohgo, Shuhei Imoto, Masayuki Amano, Nobuyo Kuwata-Higashi, Manabu Aoki, Hiroshi Abe, Hiroaki Mitsuya, Kiyoshi Fukuhara, Kazuhiro Haraguchi
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume: 81 Issue: 7 Pages: 2827-2836
- DOI
  10.1021/acs.joc.6b00105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12751, KAKENHI-PROJECT-15K09574
[Journal Article] Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents2016
- Author(s)
  Fukuda, H; Muromoto, R.; Takakura, Y.; Ishimura, K.; Kanada, R.; Fushihara, D.; Tanabe, M.; Matsubara, K.; Hirao, T.; Hirashima, K.; Abe, Arisawa, M.; Matsuda, T.; Shuto, S.
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Issue: 24 Pages: 6224-6227
- DOI
  10.1021/acs.orglett.6b02612
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01026, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-26288051, KAKENHI-PROJECT-15K12751, KAKENHI-PROJECT-15K14976, KAKENHI-PROJECT-15K18898, KAKENHI-PROJECT-15KT0063, KAKENHI-PROJECT-16K15136
[Journal Article] Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase2016
- Author(s)
  Marcus Cebula, Ilke Simsek Turan, Birgitta Sjoudin, Madhuranayaki Thulasingam, Joseph Brock, Volodymyr Chmyrov, Jerker Widengren, Hiroshi Abe, Bengt Mannervik, Jesper Haeggstroum, Agnes Rinaldo-Matthis, Engin Akkaya, Ralf Morgenstern
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 38316-38316
- DOI
  10.1038/srep38316
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12751
[Journal Article] Phosphorylated 5-ethynyl-2'-deoxyuridine for advanced DNA labeling2015
- Author(s)
  1.Seo, Siyoong; Onizuka, Kazumitsu; Nishioka, Chieko; Takahashi, Eiki; Tsuneda, Satoshi; Abe, Hiroshi; Ito, Yoshihiro
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 13 Issue: 15 Pages: 4589-4595
- DOI
  10.1039/c5ob00199d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282240
[Journal Article] Rolling Circle Translation of Circular RNA in Living Human Cells.2015
- Author(s)
  N. Abe, K. Matsumoto, M. Nishihara, Y. Nakano, A. Shibata, H. Maruyama, S. Shuto, A. Matsuda, M. Yoshida, Y. Ito, H. Abe
- Journal Title
  
  Scientific Rep
  
  Volume: 15 Issue: 1 Pages: 16435-16435
- DOI
  10.1038/srep16435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-25282240
[Journal Article] Nickel-Catalyzed Suzuki-Miyaura Coupling of a Tertiary Iodocyclopropane with Wide Boronic Acid Substrate Scope: Coupling Reaction Outcome Depends on Radical Species Stability2015
- Author(s)
  Keisuke Yotsuji, Naoyuki Hoshiya, Takaaki Kobayashi, Hayato Fukuda, Hiroshi Abe, Mitsuhiro Arisawa and Satoshi Shuto
- Journal Title
  
  Adv. Synth. Catal.
  
  Volume: 357 Issue: 5 Pages: 1022-1028
- DOI
  10.1002/adsc.201401000
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23246013, KAKENHI-PROJECT-24390023, KAKENHI-PUBLICLY-25105702, KAKENHI-PROJECT-25282240, KAKENHI-PROJECT-25670049, KAKENHI-PROJECT-26288051, KAKENHI-PROJECT-26860003, KAKENHI-PROJECT-15H02495
[Journal Article] Automatic Pseudorotaxane Formation Targeting on Nucleic Acids Using a Pair of Reactive Oligodeox-ynucleotides2014
- Author(s)
  Kazumitsu Onizuka*, Fumi Nagatsugi, Yoshihiro Ito, Hiroshi Abe
- Journal Title
  
  ournal of the American Chemical Society
  
  Volume: 136 Issue: 20 Pages: 7201-7204
- DOI
  10.1021/ja5018283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282240, KAKENHI-PROJECT-25288073, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-26860007
[Journal Article] An intracellular buildup reaction of active siRNA species from short RNA fragments.2014
- Author(s)
  Maruyama, H.; Nakashima, Y.; Shuto, S.; Matsuda, A.; Itoh, Y.; Abe, H.
- Journal Title
  
  Chem. Commun.
  
  Volume: 50 Issue: 11 Pages: 1284-1287
- DOI
  10.1039/c3cc47529h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249008, KAKENHI-PROJECT-25282240
[Journal Article] Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: Discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin2014
- Author(s)
  Shimada H, Haraguchi K, Hotta K, Miyaike T, Kitagawa Y, Tanaka H, Kaneda R, Abe H, Shuto S, Mori K, Ueda Y, Kato N, Snoeck R, Andrei G, Balzarini J.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 21 Pages: 6174-82
- DOI
  10.1016/j.bmc.2014.08.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J02962, KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-25282240, KAKENHI-PROJECT-25293110
[Journal Article] Sustained delivery of siRNA from dopamine-coated stainless steel surface2013
- Author(s)
  10. Binata Joddar*, Aydin Albayrak, Jeonghwa Kang, Mizuki Nishihara, Hiroshi Abe, Yoshihiro Ito
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 9 Pages: 6753-6761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282240
[Journal Article] Cationic cholesterol-modified gelatin as an in vitro siRNA delivery vehicle2013
- Author(s)
  P. A. Kadengodlu
- Journal Title
  
  Mol. BioSyst.
  
  Volume: 9 Issue: 5 Pages: 965-968
- DOI
  10.1039/c2mb25424g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220009, KAKENHI-PROJECT-25282240
[Journal Article] Rolling circle amplification in a prokaryotic translation system using small circular RNA2013
- Author(s)
  Naoko Abe, Michio Hiroshima, Hideto Maruyama, Yuko Nakashima, Yukiko Nakano, Akira Matsuda, Yasushi Sako, Yoshihiro Ito, Hiroshi Abe
- Journal Title
  
  Angewandte Chemie Int. Ed.
  
  Volume: x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656511
[Journal Article] Rolling circle amplification in prokaryotic translation system using small circular RNA.2013
- Author(s)
  Abe, N., Hiroshima, M., Maruyama, H., Nakashima, Y., Nakano, Y., Matsuda, A., Sako, Y., Ito, Y., and Abe, H.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 27 Pages: 7004-7008
- DOI
  10.1002/anie.201302044
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24113726, KAKENHI-PROJECT-24656511, KAKENHI-PROJECT-25282240
[Journal Article] Structure Formation and Catalytic Activity of DNA in Organic Solvents2012
- Author(s)
  Hiroshi Abe, Naoko Abe, Aya Shibata, Keiji Ito, Yoshiyuki Tanaka, Mika Ito, Hisao Saneyoshi, Satoshi Shuto, and Yoshihiro Ito
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 51 Issue: 26 Pages: 6475-6479
- DOI
  10.1002/anie.201201111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06507, KAKENHI-PROJECT-23659049, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-24656510
[Journal Article] Stmcture Formation and Catalytic Activity of DNA in Organic Solvents2012
- Author(s)
  Hiroshi Abe, Naoko Abe, Aya Shibata, Keiji Ito, Yoshiyuki Tanaka, Mika Ito, Hisao Saneyoshi, Satoshi Shuto, and Yoshihiro Ito
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 51 Pages: 6475-6479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656510
[Journal Article] Oligonucleotide-Templated, Reactions for Sensing Nucleic Acids2012
- Author(s)
  Aya Shibata, Hiroshi Abe, Yoshihiro Ito
- Journal Title
  
  Molecules
  
  Volume: 17(3) Pages: 2446-2463
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Universal Caging Group for In Cell Detection of Glutathione Transferase Applied to 19F NMR and Bioluminogenic Probes2012
- Author(s)
  Mika Ito, Aya Shibata, Jie Zhang, Michio Hiroshima, Yasushi Sako, Yukiko Nakano, Kyoko Kojima-Aikawa, Bengt Mannervik, Satoshi Shuto, Yoshihiro Ito, Ralf Morgenstern, Hiroshi Abe
- Journal Title
  
  ChemBioChem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Fluorescent Detection of Intron Lariat RNAs with Reduction-Triggered Fluorescence Probes2011
- Author(s)
  Kazuhiro Furukawa, Hiroshi Abe, Yasutsugu Tamura, Rei Yoshimoto, Minoru Yoshida, Satoshi Tsuneda, Yoshihiro Ito
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 50(50) Pages: 12020-12023
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy2011
- Author(s)
  Jie Zhang, Aya Shibata, Mika Ito, Satoshi Shuto, Yoshihiro Ito, Bengt Mannervik, Hiroshi Abe and Ralf Morgenstern
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133(35) Pages: 14109-14119
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Ralf Morgenstern, Characterization of New Potential Anticancer Drugs Designed To Overcome Glutathione Transferase Mediated Resistance2011
- Author(s)
  Katarina Johansson, Mika Ito, Carolien M. S. Schophuizen, Sherin Mathew T, Vanina D. Heuser, Jie Zhang, Miyuki Shimoji, Marie Vahter, Wee Han Ang, Paul J. Dyson, Aya Shibata, Satoshi Shuto, Yoshihiro, Ito, Hiroshi Abe
- Journal Title
  
  Molecular Pharmaceutics.
  
  Volume: 8(5) Pages: 1698-1708
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Photoactivatable fluorescein derivatives with azidomethyl caging groups for tracing oligonucleotides in living human cells.2010
- Author(s)
  Kazuhiro Furukawa, Hiroshi Abe, Satoshi Tsuneda, Yoshihiro Ito
- Journal Title
  
  Organic Biomolecular Chemistry
  
  Volume: 8 Pages: 2309-2311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22686077
[Journal Article] Reduction-triggered red fluorescent probes for dual-color detection of oligonucleotide sequences2009
- Author(s)
  Kazuhiro Furukawa, Hiroshi Abe, Jin Wang, Miwako Uda, Satoshi Tsuneda, Yoshihiro Ito
- Journal Title
  
  Organic Biomolecular Chemistry 7
  
  Pages: 671-677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750146
[Journal Article] 細胞制御材料と再生医療2009
- Author(s)
  伊藤嘉浩、北嶋隆、阿部洋
- Journal Title
  
  高分子 58(3)
  
  Pages: 129-132
- Data Source
  KAKENHI-PROJECT-19200041
[Journal Article] DNA templated nucleophilic aromatic substitution reactions for fluorogenic sensing of oligonucleotides2009
- Author(s)
  Aya Shibata, Hiroshi Abe, Mika Ito, Yuko Kondo, Shigeru Shimizu, Kyoko Aikawa Yoshihiro Ito
- Journal Title
  
  Chemical Communication 43
  
  Pages: 6586-6588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750146
[Journal Article] Reduction-triggered Fluorescent Amplification Probe for Detection of endogenous RNAs in Living Human Cells2009
- Author(s)
  Kazuhiro Furukawa, Hiroshi Abe, Kayoko Hibino, Yasushi Sako, Satoshi Tsuneda, Yoshihiro Ito
- Journal Title
  
  Bioconjugate Chemistry 20
  
  Pages: 1026-1036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750146
[Journal Article] Intermolecular transfer of aminoacylated adenosine towards chemical aminozcylation of tRNA2008
- Author(s)
  M. Liu, H. Jinmei, K. Furuzono, H. Abe, and Y. Ito,
- Journal Title
  
  Chem. Lett. 37
  
  Pages: 102-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200041
[Journal Article] Chemically fixed nurse cells for culturing murine or primate embryonic stem cells2007
- Author(s)
  Y Ito, M. Kawamorita, T. Yamabe, T. Kiyono, K. Miyamoto
- Journal Title
  
  J. Biosci. Bioeng. 103
  
  Pages: 113-121
- NAID
  110006239218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200041
[Journal Article] Rapid DNA Chemical Ligation for Amplification of RNA and DNA Signal2007
- Author(s)
  阿部洋、他
- Journal Title
  
  Bioconjyugate Chemistry 19
  
  Pages: 327-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750159
[Journal Article] alpha -C-glucoside trisphosphates based on the conformational restriction strategy.2006
- Author(s)
  M.Terauchi, H.Abe, S.C.Tovey, S.G.Dedos, C.W.Taylor, M.Paul, M.Trusselle, B.V.L.Potter, A.Matsuda, S.Shuto
- Journal Title
  
  Journal of Medicinal Chemistry 49
  
  Pages: 1900-1909
- Data Source
  KAKENHI-PROJECT-18750159
[Journal Article] Structure analysis of oligonucleotide in organic solvent.2006
- Author(s)
  阿部洋、阿部奈保子、伊藤嘉浩
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf). 50
  
  Pages: 25-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651098
[Journal Article] Design and synthesis of 5'-deoxy-5'-phenyladenophostin A, a highly potent IP3 receptor ligand.2006
- Author(s)
  T.Mochizuki, Y.Kondo, H.Abe, C.W.Taylor, B.V.L.Potter, A.Matsuda, S.Shuto
- Journal Title
  
  Organic Letter 8
  
  Pages: 1455-1458
- Data Source
  KAKENHI-PROJECT-18750159
[Journal Article] Flow cytometric detection of specific RNAs in native human cells with quenched auto ligating FRET probes2006
- Author(s)
  H.Abe, E.T.Kool
- Journal Title
  
  Proceedings of the National Academy of Sciences USA 103
  
  Pages: 263-268
- Data Source
  KAKENHI-PROJECT-18750159
[Journal Article] Synthesis of adenophostin A analogues conjugating an aromatic group at the 5'-position as potent IP3 receptor ligands.2006
- Author(s)
  T.Mochizuki, Y.Kondo, H.Abe, S.C.Tovey, S.G.Dedos, C.W.Taylor, M.Paul, B.V.Potter, A.Matsuda, S.Shuto
- Journal Title
  
  Journal of Medicinal Chemistry 49
  
  Pages: 5750-5758
- Data Source
  KAKENHI-PROJECT-18750159
[Patent] グルタチオンS－トランスフェラーゼ阻害剤2016
- Inventor(s)
  阿部洋、宍戸裕子
- Industrial Property Rights Holder
  阿部洋、宍戸裕子
- Industrial Property Rights Type
  特許
- Filing Date
  2016-07-05
- Overseas
- Data Source
  KAKENHI-PROJECT-15K12751
[Patent] 細胞内ビルドアップ型RNA2013
- Inventor(s)
  阿部洋
- Industrial Property Rights Holder
  阿部洋
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-01
- Overseas
- Data Source
  KAKENHI-PROJECT-25282240
[Patent] 蛍光発生分子2011
- Inventor(s)
  阿部洋、伊藤嘉浩、古川和寛
- Industrial Property Rights Holder
  理化学研究所
- Acquisition Date
  2011-03-31
- Overseas
- Data Source
  KAKENHI-PROJECT-22686077
[Patent] 蛍光発生分子2008
- Inventor(s)
  阿部洋、伊藤嘉浩、古川和寛、王瑾
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Filing Date
  2008-01-09
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] 核酸医薬のための分子デザイン2020
- Author(s)
  阿部　洋
- Organizer
  第415回　CBI学術講演会「広がりゆく核酸医薬」
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 生命をだまして薬をつくる2019
- Author(s)
  阿部　洋
- Organizer
  第29回　名古屋大学理学部懇話会　2019年6月16日
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Synthetic oligonucleotides for gene silencing method2019
- Author(s)
  Hiroshi Abe
- Organizer
  China Trends in Nucleic Acid (TINA) 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Membrane Permeable Oligonucleotides based on Disulfide Unit2019
- Author(s)
  Zhaoma Shu, Iku Tanaka, Azumi Ota, Fumiaki Tomoike, Naoko Abe, Hiroshi Abe
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] RNAの形状デザインに基づく機能設計2019
- Author(s)
  阿部　洋
- Organizer
  名古屋市立大学薬学部、薬学会東海支部特別講演会、2019年4月24日
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] RNA 創薬 ―生命をだまして薬をつくるー2019
- Author(s)
  阿部　洋
- Organizer
  愛知サイエンスフェステバル
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] ケミカルライゲーション法による環状RNAの構築とその翻訳評価2019
- Author(s)
  中本航介、阿部奈保子、阿部洋
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 人工核酸による翻訳機能制御2019
- Author(s)
  阿部　洋
- Organizer
  先端化学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 二次構造形成によるmRNAの翻訳反応制御2019
- Author(s)
  川口大輔、清水沙彩、阿部奈保子、友池史明、木村康明、阿部洋
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 新規核酸ケミカルライゲーション反応の開発2019
- Author(s)
  小久保建吾、山岡和樹、中本航介、友池史明、木村康明、阿部洋
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 迅速に細胞質分布するアンチセンス核酸・siRNAの開発2019
- Author(s)
  阿部　洋
- Organizer
  新学術領域研究第 8 回成果報告会　京都大学桂キャンパス船井晢良記念講堂　2019年5月31日
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] タンパク合成を効率化するめのｍRNAの分子デザイン2019
- Author(s)
  阿部　洋
- Organizer
  協和キリンセミナー東京　町田　2019年9月24日
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Molecular Design of mRNA improving translation reaction2019
- Author(s)
  Hiroshi Abe
- Organizer
  CISNAC2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Nano-structured RNA for drug discovery2019
- Author(s)
  Hiroshi Abe
- Organizer
  China NANO 2019, 8th International Conference on Nanoscience and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Shape Design of RNA Molecule Provides General Functions2019
- Author(s)
  Hiroshi Abe
- Organizer
  Core-to-Core and GTR Symposium on Elements Function for transformative Catalysis and Materials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Molecular Design of mRNA improving translation reaction2019
- Author(s)
  Hiroshi Abe
- Organizer
  the 9th Inter national Conference on Nucleic Acid-Protein Chemical and Structural Biology for Drug Discovery at Sichuan University, China, August 13th-16th, 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] Synthetic Oligonucleotide for Drug Discovery2019
- Author(s)
  Hiroshi Abe
- Organizer
  NU-UoE JD and JSPS Core-to-Core Joint-Workshop on "New Horizons in Chemistry and Materials Science"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 膜透過性核酸の開発2019
- Author(s)
  川口紗貴, Zhaoma Shu, 太田杏摘, 中本航介, 阿部奈保子, 友池史明, 木村康明, 阿部洋
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] ケミカルライゲーション法による環状RNAの構築とその翻訳評価2018
- Author(s)
  中本航介, 阿部奈保子, 阿部洋
- Organizer
  日本化学会　第99回
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] Nano-structured RNA for drug discovery2018
- Author(s)
  Naoko Abe, Hiroshi Abe
- Organizer
  FNA Perth 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] 真核生物における環状RNAを用いた終わりのない回転式翻訳現象2018
- Author(s)
  清水沙彩、児玉亜有実、阿部奈保子、友池史明、木村康明、阿部洋
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] 膜透過性核酸の開発2018
- Author(s)
  Zhaoma Shu, Iku Tanaka, Azumi Ota, Naoko Abe, Seiichi Tada，Yoshihiro Ito, Hiroshi Abe
- Organizer
  第34回　日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] The development of membrane permeabable oligonucleotides2018
- Author(s)
  Zhaoma Shu, Iku Tanaka, Azumi Ota, Naoko Abe, Seiichi Tada，Yoshihiro Ito, Hiroshi Abe
- Organizer
  ISNAC2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 潜在性カチオン分子を利用したオリゴ核酸の膜透過性向上2018
- Author(s)
  田中育, 太田杏摘, 伏原大地, Shu Zhaoma, 阿部奈保子, 友池史明, 木村康明, 多田誠一, 阿部洋
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] ジスルフィド構造導入によるオリゴ核酸の膜透過性向上2018
- Author(s)
  田中育, 太田杏摘, 伏原大地, Shu Zhaoma, 阿部奈保子, 友池史明, 木村康明, 多田誠一, 阿部洋
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 真核生物における環状RNAを用いた終わりのない回転式翻訳現象2018
- Author(s)
  阿部奈保子、清水沙彩、児玉亜有実、友池史明、木村康明、阿部洋
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] Circular RNA for protein translation2018
- Author(s)
  Naoko Abe, Hiroshi Abe
- Organizer
  FNA Perth 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] Improvement of Oligonucleotide Cellular Uptake with Latently Cationic Molecules2018
- Author(s)
  Azumi Ota, Zhaoma Shu, Iku Tanaka, Daichi Fushihara, Naoko Abe, Fumiaki Tomoike, Yasuaki Kimura, Seiichi Tada, Yoshihiro Ito, Hiroshi Abe
- Organizer
  ISNAC2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04398
[Presentation] 光解除性保護基を有するヌクレオシドを利用した長鎖RNAのケミカルライゲーション2017
- Author(s)
  辻厳一郎, 笈川涼太, 早川真由, 木村康明, 阿部洋
- Organizer
  統合物質創製化学研究推進機構第２回国内シンポジウム
- Place of Presentation
  北海道
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 求電子的ホスホロチオエステルによる核酸の化学的連結反応2017
- Author(s)
  木村康明, 丸山豪斗, 笈川涼太, 早川真由, 阿部奈保子, 松田彰, 周東智, 伊藤嘉浩, 阿部洋
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 機能性核酸合成を志向した化学的核酸連結反応2017
- Author(s)
  笈川涼太、早川真由、丸山豪斗、阿部奈保子、木村康明、周東智、松田彰、南川典昭、阿部洋
- Organizer
  日本核酸医薬学会第３回年会
- Data Source
  KAKENHI-PROJECT-15H04656
[Presentation] ビルドアップ型核酸分子の開発2017
- Author(s)
  吉永静也, 辻厳一郎, 阿部奈保子, 友池史明, 木村康明, 阿部洋
- Organizer
  統合物質創製化学研究推進機構第２回国内シンポジウム
- Place of Presentation
  北海道
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 共有結合型グルタチオンS-転移酵素阻害剤の創薬研究2017
- Author(s)
  宍戸裕子, 藤川遥加, 木村康明, 友池史明, 桑田啓子, 矢野貴人, 福井健二, 関戸好孝, 村上優子, 周東智, 阿部洋
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 環状RNAを鋳型にしたローリングサークル翻訳反応2017
- Author(s)
  阿部奈保子、児玉亜有実、清水沙彩、友池史明、木村康明、伊藤嘉浩、阿部洋
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] 高効率な核酸検出を可能にする核酸鋳型反応の開発2017
- Author(s)
  伊藤真央　柴田綾　阿部奈保子　木村康明　阿部洋
- Organizer
  日本薬学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16KT0052
[Presentation] 高効率な核酸検出を可能にする核酸鋳型反応の開発2017
- Author(s)
  伊藤真央, 柴田綾, 阿部奈保子, 木村康明、阿部洋
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] ヒト細胞における環状RNAのローリングサークル型翻訳反応2017
- Author(s)
  阿部奈保子、児玉亜有実、清水沙彩、友池史明、木村康明、伊藤嘉浩、阿部洋
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] 糖部三員環型ヌクレオシドアナログの創成2017
- Author(s)
  伏原大地, 福田隼, 阿部洋, 周東智
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 合成環状RNAからのタンパク質発現2016
- Author(s)
  児玉亜有実, 阿部奈保子, 友池史明, 伊藤嘉浩, 松本健, 吉田稔, 清水義宏, 亀田倫史, 阿部洋
- Organizer
  第39回分子生物学会
- Data Source
  KAKENHI-PROJECT-16H04178
[Presentation] Development of novel chemical ligation reaction for RNA strands2016
- Author(s)
  笈川涼太, 丸山豪斗, 早川真由, 阿部奈保子, 木村康明, 阿部洋
- Organizer
  第43回　国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 細胞内ビルドアップ型SiRNAを指向した新規核酸連結反応2016
- Author(s)
  早川真由, 笈川涼太, 丸山豪斗, 阿部奈保子, 木村康明, 周東智, 松田彰, 阿部洋
- Organizer
  日本核酸医薬学会第二回年会
- Place of Presentation
  東京
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 人工核酸によるRNA機能の解析と制御2016
- Author(s)
  阿部洋
- Organizer
  2015年度東海高分子学生研究会
- Place of Presentation
  名古屋
- Year and Date
  2016-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 共有結合型グルタチオン S-転移酵素阻害剤の創薬研究2016
- Author(s)
  宍戸裕子, 藤川遥加, 木村康明, 友池史明, 桑田啓子, 矢野貴人, 福井健二, 関戸好孝, 村上優子, 周東智, 阿部洋
- Organizer
  第34回メデシナルケミストリーシンポジウム
- Place of Presentation
  つくば
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] Nile Blueを基本骨格とした脂肪滴検出プローブの創製2016
- Author(s)
  戸田直宏, 伊藤美香, 石田綾乃, 鬼頭宏任, 横川大輔, Stephan Irle, 木村康明, 友池史明, 西村智, 阿部洋
- Organizer
  第31回生体機能関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 合成環状RNAからのタンパク質発現2016
- Author(s)
  児玉亜有実, 阿部奈保子, 友池史明, 伊藤嘉浩, 松本健, 吉田稔, 清水義宏, 亀田倫史, 阿部洋
- Organizer
  第39回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] Si-Si結合の特性を利用した光分解性保護基の開発2016
- Author(s)
  伊藤真央, 金田龍太郎, 木村康明, 周東智, 阿部洋
- Organizer
  第31回生体機能関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K12751
[Presentation] 人工核酸を用いた細胞内RNAの解析及び機能制御2015
- Author(s)
  阿部洋
- Organizer
  第一回新しい原子分子組織化物質・材料創出に向けた光・量子ビーム応用技術調査専門委員会
- Place of Presentation
  名古屋大学
- Year and Date
  2015-05-08
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 合成環状RNAからのタンパク質発現2015
- Author(s)
  阿部洋，阿部奈保子, 伊藤嘉浩, 松本健, 吉田稔
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 低分子RNAから活性型高分子RNAを細胞内でビルドアップする方法論の開発2015
- Author(s)
  阿部　洋、丸山豪斗、周東　智、松田　彰
- Organizer
  RNA meeting 2015 in Sapporo
- Place of Presentation
  札幌
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 細胞内RNAの解析と機能制御2015
- Author(s)
  阿部洋
- Organizer
  特別招待セミナー(愛知がんセンター)
- Place of Presentation
  愛知がんセンター
- Year and Date
  2015-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] Synthetic biology of Circular RNA2014
- Author(s)
  Hiroshi Abe
- Organizer
  RIKEN SYPOSIUM & 15th Tokyo RNA club
- Place of Presentation
  Wako-shi
- Year and Date
  2014-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] RNAのナノ構造化に基づく機能創発2014
- Author(s)
  阿部洋
- Organizer
  RNAインフォマティクス道場in 札幌
- Place of Presentation
  産総研北海道センター
- Year and Date
  2014-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 標的を触媒として利用する遺伝子検出のための化学反応プローブの開発2014
- Author(s)
  阿部洋
- Organizer
  若手研究者のための有機化学札幌セミナー
- Place of Presentation
  北海道大学理学部5号館
- Year and Date
  2014-11-17
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] RNAナノ構造化による医薬機能創発2014
- Author(s)
  阿部洋
- Organizer
  第25回未来創薬・医療イノベーションセミナー
- Place of Presentation
  北海道大学、札幌市
- Year and Date
  2014-07-09
- Invited
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] DNA templated reaction for efficient signal amplification and its steady-state kinetic analysis of the turnover cycle2014
- Author(s)
  Hiroshi Abe, Aya Shibata, Takanori Uzawa, Yoshihiro Ito, Satoshi Shuto
- Organizer
  The 41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kitakyushu-shi
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25282240
[Presentation] 生細胞内遺伝子の解析と制御を目的とした機能正核酸分子の創製2012
- Author(s)
  阿部洋
- Organizer
  次代を担う若手大学人育成イニシアティブセミナー
- Place of Presentation
  筑波大学下田臨界実験センター、下田市(招待講演)
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 生細胞内遺伝子の解析と制御を目的とした機能正核酸分子の創製2012
- Author(s)
  阿部洋
- Organizer
  次代を担う若手大学人育成イニシアティブセミナー
- Place of Presentation
  筑波大学下田臨界実験センター、下田市
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] Peroxidase Activity of G-Quadraplex Hemin-Binding DNA Aptamers Determined by Electrochemical Measurement2012
- Author(s)
  Kubo I, Hoshino Y, Liu Mingzhe, Abe Hiroshi, Ito Yoshihiro
- Organizer
  Prime 2012
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-24656510
[Presentation] 医療応用を目指した人工核酸分子の創製2011
- Author(s)
  阿部洋
- Organizer
  高分子学会関東支部第22回埼玉地区談話会
- Place of Presentation
  東洋大学川越キャンパス、川越市
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 遺伝子シグナルの化学的増幅2011
- Author(s)
  阿部洋
- Organizer
  トクシマ・ファルマ・トライアングル(TPT)構築事業特別講演会
- Place of Presentation
  徳島大学薬学部、徳島市
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 遺伝子シグナルの化学的増幅2011
- Author(s)
  阿部洋
- Organizer
  トクシマ・ファルマ・トライアングル(TPT)構築事業特別講演会
- Place of Presentation
  徳島大学薬学部、徳島市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 人工核酸分子を用いた遺伝子発現の解析と制御2010
- Author(s)
  阿部洋
- Organizer
  大阪大学免疫学フロンティア研究センター
- Place of Presentation
  大阪市
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 人工核酸分子を用いた遺伝子発現の解析と制御2010
- Author(s)
  阿部洋
- Organizer
  大阪大学免疫学フロンティア研究センターセミナー
- Place of Presentation
  大阪大学
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22686077
[Presentation] 芳香族求核置換反応を引き金とした新規蛍光発生分子システムを導入した遺伝子検出プローブの開発2010
- Author(s)
  伊藤美香, 柴田綾, 阿部洋, 中嶋裕子, 清水繁, 相川京子, 伊藤嘉浩
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] RNA情報を釣り針とする微生物生細胞の分離・濃縮技術の開発2009
- Author(s)
  古川和寛, 阿部洋, 常田聡, 伊藤嘉浩
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] Chemical reaction triggered fluorogenic probe for RNA detection in living cells2009
- Author(s)
  Hiroshi Abe
- Organizer
  BIT's 3^<rd> world congress of Gene-2009
- Place of Presentation
  Foshan, China
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] 金属結合ペプチド融合蛋白質の創製と金属ナノ粒子への結合評価2009
- Author(s)
  阿部祥子
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学
- Data Source
  KAKENHI-PROJECT-19200041
[Presentation] 機能性人工核酸の創製2008
- Author(s)
  阿部洋
- Organizer
  分子研研究会-物質系と生体系での自己組織化-
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-19651098
[Presentation] 新規蛍光化合物を導入したプローブよる遺伝子シグナルの化学増幅2008
- Author(s)
  阿部洋、古川和寛、王瑾、烏田美和子、常田聡、伊藤嘉浩
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  大阪、ポスター
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] 細胞内RNA検出プローブの開発2008
- Author(s)
  阿部洋、古川和寛、王瑾、烏田美和子、常田聡、伊藤嘉浩
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] 新規蛍光化合物を導入した化学反応プローブによる遺伝子シグナルの増幅2008
- Author(s)
  阿部洋
- Organizer
  第3回バイオ関連化学合同シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20750146
[Presentation] 核酸の有機溶媒可溶化と構造解析2007
- Author(s)
  阿部洋、阿部奈保子、神明博、伊藤嘉浩
- Organizer
  第56回高分子学会年次大会
- Place of Presentation
  京都
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-19651098
[Presentation] 有機溶液に溶ける核酸の構造解析:有機溶媒中のGカルテット構造2007
- Author(s)
  阿部洋、阿部奈保子、伊藤嘉浩
- Organizer
  第56回高分子討論会
- Place of Presentation
  名古屋
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-19651098

1. ITO Yoshihiro (40192497)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. Asai Kiyoshi (30356357)

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6. KITAJIMA Takashi (40399556)

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7. WANG Wei (30632955)

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8. TADA Seiichi (30598165)

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27. 友池史明

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abe hiroshi 阿部 洋

ABE Hiroshi 阿部 洋

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新規翻訳誘導技術を用いた環状RNAの分子設計と応用Principal Investigator

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Medium molecularization strategy of high molecular weight RNA medicinePrincipal Investigator

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Improvement of catalytic turnover based on transition state control of oligonucleotide template chemical reactionPrincipal Investigator

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Protein synthesis using circular RNAPrincipal Investigator

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Development of molecular probe for GSTPrincipal Investigator

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Development of RNA medicine based on nano-structured design and templated reactionPrincipal Investigator

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abe hiroshi 阿部洋

ABE Hiroshi 阿部洋

[Book] 化学　Vol.74　No.82019