Sugihara Masami 杉原匡美

Researcher Number	80648163
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 順天堂大学, 医学部, 准教授 2015 – 2022: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 59010:Rehabilitation science-related / Applied health science Except Principal Investigator Basic Section 48020:Physiology-related / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator 心室性不整脈 / 心不全 / 拡張型心筋症 / 運動療法 / 不整脈 / レニン・アンギオテンシン阻害薬 Except Principal Investigator カルシウム遊離チャネル / 筋小胞体 / 骨格筋 / カルシウムイオン … More / 筋収縮 / 興奮収縮連関 / カルシウムチャネル / リアノジン受容体 / 創薬 / 心筋 / 機能抑制型変異 / カルシウム / 抗不整脈薬 / 不整脈 / 2型リアノジン受容体 Less

家族性拡張型心筋症モデルにおける運動療法の効果Principal Investigator
- Principal Investigator
  
  杉原匡美
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agents
- Principal Investigator
  
  呉林なごみ
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system
- Principal Investigator
  
  村山尚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
The construction of exercise therapy in familial DCM model micePrincipal Investigator
- Principal Investigator
  
  杉原匡美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
The construction of combination therapy of exercise and medication on DCM model micePrincipal Investigator
- Principal Investigator
  
  Sugihara Masami
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
The construction of exercise therapy on DCM model micePrincipal Investigator
- Principal Investigator
  
  Sugihara Masami
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University

All 2023 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca<sup>2+</sup>Monitoring2023
- Author(s)
  Takenaka Mai、Kodama Masami、Murayama Takashi、Ishigami-Yuasa Mari、Mori Shuichi、Ishida Ryosuke、Suzuki Junji、Kanemaru Kazunori、Sugihara Masami、Iino Masamitsu、Miura Aya、Nishio Hajime、Morimoto Sachio、Kagechika Hiroyuki、Sakurai Takashi、Kurebayashi Nagomi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 104 Issue: 6 Pages: 275-286
- DOI
  10.1124/molpharm.123.000720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652
[Journal Article] Current smorkers with hyperlipidemia lack slevated preβ-high-dencity lipoprotein concentrations．2017
- Author(s)
  Yuki Nagao, Satoshi Hirayama, Mika Kon, Kenta Sasamoto, Masami Sugihara, Akiko Hirayama, Miwa Isshiki, Utako Seino, Osamu Miyazaki, Takashi Miida
- Journal Title
  
  Jurnal od Clinical Lipidology
  
  Volume: １ Issue: 1 Pages: 242-249
- DOI
  10.1016/j.jacl.2016.12.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16523, KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-26461644
[Journal Article] The bromocresol green assay, but not the modified bromocresol purple assay, overestimates the serum albumin concentration in nephrotic syndrome through reaction with α2-macroglobulin.2015
- Author(s)
  Ueno T, Hirayama S, Sugihara M, Miida T
- Journal Title
  
  Annals of Clinical Biochemistry
  
  Volume: 53 Issue: 1 Pages: 97-105
- DOI
  10.1177/0004563215574350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K16523, KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-26461644
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の頻度と詳細2023
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, Inoue YU, Inoue T, Noguchi S and Sakurai T
- Organizer
  67th Biophysical Society Anual lMeeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] EFFECTS OF VOLUNTARY EXERCISE AND ADMINISTRATION OF RENIN ANGIOTENSIN INHIBITOR ON CARDIAC FUNCTION IN INHERITED DILATED CARDIOMYOPATHY MODEL2023
- Author(s)
  Masami Sugihara,Ryo Kakigi,Takashi Murayam,Takashi Miida,Takashi Sakura,,Sachio Morimoto,Nagomi Kurebayashi
- Organizer
  第67回米国生物物理学会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, U-Inoue Y, Inoue T, Satoru N and Sakurai T
- Organizer
  第100回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 拡張型心筋症モデルマウスにおける自発運動とレニン・アンギオテンシン阻害剤投与の比較2022
- Author(s)
  杉原匡美、柿木亮、村山尚、櫻井隆、三井田孝、森本幸生、呉林なごみ
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍（CPVT）に対する抗不整脈薬の評価2022
- Author(s)
  呉林なごみ, 児玉昌美, 村山尚, 杉原匡美, 石井光一郎, 岡部雄太, 村越伸行, 三浦綾, 西尾元, 井上-上野由紀子, 井上高良, 野口悟, 中村衣里, 金井富三夫, 多田昇弘櫻井隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の効果2021
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の効果2021
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-18K17686
[Presentation] 拡張型心筋症モデルマウスにおける性差による自発運動の効果の違い2020
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第93回日本薬理学会年会（紙上開催）
- Data Source
  KAKENHI-PROJECT-18K17686
[Presentation] 拡張型心筋症モデルマウスにおける性差による自発運動の効果の違い2020
- Author(s)
  杉原匡美, 柿木亮, 村山尚, 三井田孝,櫻井隆, 森本幸生, 呉林なごみ
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K17686
[Presentation] 拡張型心筋症モデルにおける性差による自発運動の効果の違い2020
- Author(s)
  杉原匡美, 柿木亮, 村山尚, 平山哲, 三井田孝, 森本幸生, 呉林なごみ
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K17686
[Presentation] Relation between voluntary exercise frequency and cardiac function in dilated cardiomyopathy model mice2018
- Author(s)
  Sugihara M, Kakigi R, Murayama T, Sakurai T, Miida T, Morimoto S, Kurebayashi N
- Organizer
  62th Biophysical Society Annual Meeting
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の頻度と心不全進行との関係2018
- Author(s)
  杉原匡美，柿木亮，村山尚，平山哲，森本幸生，呉林なごみ，三井田孝
- Organizer
  第65回日本臨床検査医学学術集会
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] The Comparison of Voluntary and Forced Exercises on Cardiac Function of DCM Model Mice2017
- Author(s)
  Masami Sugihara, Ryo kakigi, Takashi murayama, Takashi Sakurai, Takashi Miida, Sachio Morimoto, Nagomi Kurebayashi
- Organizer
  第61回米国生物物理学会
- Place of Presentation
  ニューオリンズ
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] 拡張型心筋症モデルマウスにおける自発運動と強制運動の効果2017
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] The Effects of Voluntary and Forced Exercises on Cardiac Function of DCM Model Mice2017
- Author(s)
  Sugihara M, Kakigi R, Murayama T, Hirayama S, Miida T, Sakurai T, Morimoto S,Kurebayashi N,
- Organizer
  3nd Congress International Academy of Sportology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] 拡張型心筋症モデルマウスにおける自発運動と強制運動2017
- Author(s)
  杉原　匡美、柿木　亮、村山　尚、平山　哲、森本　幸生、呉林　なごみ、三井田　孝
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] Voluntary exercise on cardiac function in DCM model mice2016
- Author(s)
  Masami Sugihara, Ryo Kakigi, Takashi Murayama, Takashi Sakurai, Takashi Miida, Sachio Morimoto, Nagomi Kurebayashi
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] Effects of voluntary exercise on cardiac function in DCM model mice2016
- Author(s)
  Masami Sugihara, Ryo Kakigi, Takashi Murayama, Takashi Sakurai, Takashi Miida, Sachio Morimoto, Nagomi Kurebayashi
- Organizer
  60th Biophysical Society Annual Meeting
- Place of Presentation
  Los Angeles
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] Voluntary exercise preserves cardiac function in DCM model mice2015
- Author(s)
  Masami Sugihara, Takashi Miida, Ryo Kakigi, Takashi Murayama, Satoshi Hirayama, Sachio Morimoto, Nagomi Kurebayashi
- Organizer
  第2回　国際スポートロジー学会
- Place of Presentation
  東京
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16523
[Presentation] 自発的運動は拡張型心筋症モデルマウスの心不全進行を遅延させる2015
- Author(s)
  3)杉原　匡美、柿木　亮、村山　尚、平山　哲、森本　幸生、呉林　なごみ、三井田　孝
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  岐阜
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K16523

1. 呉林なごみ (50133335)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. 村山尚 (10230012)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. 柿木亮 (70614931)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
4. 小川治夫 (40292726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 石田良典 (10937684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 岡本瑞穂 (90964148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小林琢也 (60468585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 冨田拓郎 (60705060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

Sugihara Masami 杉原 匡美

Research Projects

Research Products

Co-Researchers

家族性拡張型心筋症モデルにおける運動療法の効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agents

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The construction of exercise therapy in familial DCM model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The construction of combination therapy of exercise and medication on DCM model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The construction of exercise therapy on DCM model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca<sup>2+</sup>Monitoring2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current smorkers with hyperlipidemia lack slevated preβ-high-dencity lipoprotein concentrations．2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The bromocresol green assay, but not the modified bromocresol purple assay, overestimates the serum albumin concentration in nephrotic syndrome through reaction with α2-macroglobulin.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 拡張型心筋症モデルマウスにおける自発運動の頻度と詳細2023

Author(s)

Organizer

Data Source

[Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023

Author(s)

Organizer

Data Source

[Presentation] EFFECTS OF VOLUNTARY EXERCISE AND ADMINISTRATION OF RENIN ANGIOTENSIN INHIBITOR ON CARDIAC FUNCTION IN INHERITED DILATED CARDIOMYOPATHY MODEL2023

Author(s)

Organizer

Data Source

[Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models2023

Author(s)

Organizer

Data Source

[Presentation] 拡張型心筋症モデルマウスにおける自発運動とレニン・アンギオテンシン阻害剤投与の比較2022

Author(s)

Organizer

Data Source

[Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍（CPVT）に対する抗不整脈薬の評価2022

Author(s)

Organizer

Data Source

[Presentation] 拡張型心筋症モデルマウスにおける自発運動の効果2021

Sugihara Masami 杉原匡美

[Presentation] 自発的運動は拡張型心筋症モデルマウスの心不全進行を遅延させる2015