SATO Tsutomu 佐藤勤

Researcher Number	90235367
External Links
Affiliation (based on the past Project Information) *help	2003 – 2006: 秋田大学, 医学部, 助教授 2000 – 2003: Akita University, School of Medicine, LECTURER, 医学部, 講師 1994 – 1999: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / General surgery / General surgery Except Principal Investigator Digestive surgery / Digestive surgery / General surgery
Keywords	Principal Investigator 肝幹細胞 / 肝幹細胞移植 / liver resection / tight junction / prostaglandin E_1 / portal venous pressure / shear stress / 門脈遮断 / hypoxia inducible factor / heme oxygenase 1 … More / heat shock protein / portal vein occlusion / neovascularization / hepatic stem cell / 低酸素負荷 / 血管内皮前駆細胞 / HIF-1 / 虚血耐性 / 血管新生 / 肝微小循環 / liver failure / splenic transposition / portal embolization / liver epithelial (stem-like) cell / 脾内肝移植 / 門脈結紮肝 / 脾内肝細胞 / 肝不全 / 脾臓皮下固着 / 門脈塞栓 / 肝上皮細胞 / 門脈圧 / 肝再生 / タイト結合 / 拒絶反応 / 神経成長因子 / 消化管運動機能障害 / 小腸移植 / nerve growth factor(NGF) / 肝流入血行遮断 / apoptosis / 抗single-stranded DNA抗体 / DNA損傷 / 肝切除 … More Except Principal Investigator protein kinase A / phosphodiesterase-3 inhibitor / cyclic AMP / 虚血再灌流傷害 / PDTC / NKH477 / 肝虚血再灌流障害 / Total body irradiation / Bone marrow transplantation / 放射線照射 / 骨髄移植 / heat shock protein / NICK / Heat Shock Protein / Kupffer cell / Hepatic sinusoidal diameter / Microcirculation / Ischemia-reperfusion injury / Hepatic stellate cell / 活性抑制 / 類洞細胞 / クッパー細胞 / 類洞径 / 微小循環 / 虚血再灌流障害 / 肝星細胞 / liver transplantation / reperfusion injury / hepatic ischemia / Phosphodiesterase inhibitor-3 / Protein kinase A / 肝虚血再灌流傷害 / 肝臓移植 / heme oxygenase-1 / splenic transposition / portal vein occlusion / liver epithelial cell / ヘムオキシゲナーゼ / 低酸素耐性 / 肝幹細胞 / AFP陽性 / 肝虚血耐性 / ヘムオキシゲナーゼ-1 / 熱ショック蛋白 / 脾臓皮下固着 / 門脈遮断 / 肝上皮性細胞 / engraftment / islet transplantation / neutrophl elastase inhibitor / グラフト生着率 / 好中球浸潤 / 生着率 / 膵島移植 / 好中球エラスターゼ阻害剤 / Defense system / Liver protection / PDE-III inhibitor / Olprinone / Milrinone / ischemia-reperfusion injury / 肝微小環境 / adenylate cyclase stimulator / 肝虚血再潅流障害 / 細胞内シグナル伝達 / PDEIII inhibitor / cvclic AMP / HO-1 / cAMP / 肝阻血再灌流障害 / PDE / 生体防御 / 肝保護 / PDEIII阻害剤 / オルプリノン / ミルリノン / kidney transplantation / Islet cell transplantation / 腎移植 / ランゲルハンス島移植 / Small bowel transplantation / 小腸移植 / hepatic metabolism / hepatic vascular exclusion / hepatoma / Hepatic cirrhosis / 熱ショックタンパク / 肝代謝 / 肝血行遮断 / 肝癌 / 肝硬変 / Ischemia and reperfusion-injury / DNA injury / Hepatic injury / 阻血再潅流障害 / 近赤外分光々光計 / Heat Shock protein / 阻血再凍流障害 / DNA損傷 / 肝障害 / 糖尿病 / 幹細胞 / 膵管結紮モデル / 近赤外分光法 / 肝移植 / nitric oxide Less

Management of hepatic ischemia-reperfusion injury by suppressing the hepatic stellate cell activation.
- Principal Investigator
  
  YOSHIOKA Masato
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Induction of Ischemic Tolerance by Augmentation of Hepatic Stem Cells in the Rat
- Principal Investigator
  
  MIYAZAWA Hideaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Tolerance induction against hepatic ischemia/reperfusion injury by an artificial regulation of the intracellular signal
- Principal Investigator
  
  KUME Makoto
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Study on neovascularization and establishment of microcirculation for the function of hepatic stem cells transplanted to the liverPrincipal Investigator
- Principal Investigator
  
  SATO Tsutomu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Akita University
Amelioration of engraftment after islet transplantation
- Principal Investigator
  
  SHIBATA Satoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Research of the intracellular transmission mechanism of the information concerning stress response
- Principal Investigator
  
  YAMAMOTO Yuzo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
  Kyoto University
糖尿病患者における自己膵幹細胞ラ氏島化の試み
- Principal Investigator
  
  KOYAMA Kenji
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Differentiation of hepatic stem cells into hepatocytes by biotechnology and those transplantation to the liver-like spleen with diversion of portal blood flowPrincipal Investigator
- Principal Investigator
  
  SATO Tsutomu, 小山研二
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Study for improvement of islet cell transplantation by renal transplantation with micro cell chimerism
- Principal Investigator
  
  FURUYA Tomoki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Akita University
Changes in Function of Hepatocyte Tight Junctions and Deal with Endotoxin by Hepatocytes after Hepatic ResectionPrincipal Investigator
- Principal Investigator
  
  SATO Tsutomu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
小腸移植後の神経系再構築における神経成長因子の役割Principal Investigator
- Principal Investigator
  
  佐藤勤
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  Akita University
How to improve the safety of total hepatic vascular exclusion for hepatectomy in hepatoma with cirrhosis
- Principal Investigator
  
  KOYAMA Kenji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Study for improvement of small bowel transplantation by donor bone marrow transplantation or total body irradiation
- Principal Investigator
  
  FURUYA Tomoki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Akita University
Nitric oxide産生抑制による生体部分肝移植後肝不全の予防
- Principal Investigator
  
  浅沼義博
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
核DNA損傷度測定による肝切除における血流不良域の評価と処置法Principal Investigator
- Principal Investigator
  
  佐藤勤
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  Akita University
Reduction of Hepatic Injury after Hepatic Surgery by Advance Induction of Heart Shock Protein and Hepatic Oxygenation
- Principal Investigator
  
  KOYAMA Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  AKITA UNIVERSITY

All 2004 2003

All Journal Article

[Journal Article] Enhanced proliferation of hepatic progenitor cells in rats after portal branch occlusion.2004
- Author(s)
  Ise N, Sato_T, Yasui O, Watanabe G, Koyama K, Terada K, Sugiyama T.
- Journal Title
  
  Liver Transpl 10
  
  Pages: 748-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Enhanced proliferation of hepatic progenitor cells in rats after portal branch occlusion.2004
- Author(s)
  Ise N, Sato T, Yasui O, Watanabe G, Koyama K, Terada K, Sugiyama T.
- Journal Title
  
  Liver Transplantation 10
  
  Pages: 748-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591287
[Journal Article] Enhanced proliferation of hepatic progenitor cells in rats after portal branch occlusion2004
- Author(s)
  Ise N, Sato T, Yasui O, Watanabe G, Koyama K, Terada K, Sugiyama T
- Journal Title
  
  Liver transplantation 10
  
  Pages: 748-754
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591287
[Journal Article] Enhanced proliferation of hepatic progenitor cells in rats after portal branch occlusion2004
- Author(s)
  Ise N, Sato T, Yasui O, et al.
- Journal Title
  
  Liver Transplantation 10・6
  
  Pages: 748-754
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Treatment of postoperative liver failure after major hepatectomy under hepatic total vascular exclusion2003
- Author(s)
  Asanuma Y, Sato T, Yasui O, et al.
- Journal Title
  
  Journal of Artificial Organs 6
  
  Pages: 152-156
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Two cases of hepatic artery interruption after hepatopancreatobiliary surgery treated by prostaglandin El infusion via the superior mesenteric artery.2003
- Author(s)
  Sato_T, Yasui O, Kurokawa T, Andoh H, Yoshioka M, Asanuma Y, Hashimoto M, Koyama K.
- Journal Title
  
  Hepato Res 25
  
  Pages: 92-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Efficacy of continuous infusion of PGE1 through the superior mesenteric artery against ischemic liver cell necrosis after hepatic arterial occlsuion2003
- Author(s)
  Kato T, Sato T, Kurokawa T, et al.
- Journal Title
  
  Transplantation 76
  
  Pages: 1340-1345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Efficacy of continuous infusion of prostaglandin E through the superior mesenteric artery against ischemic liver cell necrosis after hepatic arterial occlusion.2003
- Author(s)
  Kato T, Sato_T, Kurokawa T, Nanjo H, Asanuma Y, Koyama K.
- Journal Title
  
  Transplantation 76
  
  Pages: 1340-1345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Two cases of hepatic artery interruption after hepatopancreatobiliary surgery treated by PGE1 infusion via the superior mesenteric artery2003
- Author(s)
  Sato T, Yasui O, Kurokawa T, et al.
- Journal Title
  
  Hepatology Research 25
  
  Pages: 92-97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591324
[Journal Article] Treatment of postoperative liver failure after major hepatectomy under hepatic total vascular exclusion.2003
- Author(s)
  Asanuma Y, Sato_T, Yasui O, Kurokawa T, Koyama K.
- Journal Title
  
  J Artif Organs 6
  
  Pages: 152-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591324

1. KOYAMA Kenji (80004638)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. YAMAMOTO Yuzo (70281730)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MIYAZAWA Hideaki (10323148)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. OUKI Yasui (40323141)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. SHIBATA Satoshi (40333934)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. FURUYA Tomoki (60250891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SATO Yasuhiko (80235407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ITO Masanao (80282169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ANDOH Hideaki (00323147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAOKA Yoshio (90089102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TERAJIMA Hiroaki (40314215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IIDA Masatake (90372325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUME Makoto (00372326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOSHIOKA Masato (40375275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 浅沼義博 (20142937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉野裕顕 (90182807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SATO Tsutomu 佐藤 勤

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Study on neovascularization and establishment of microcirculation for the function of hepatic stem cells transplanted to the liverPrincipal Investigator

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Differentiation of hepatic stem cells into hepatocytes by biotechnology and those transplantation to the liver-like spleen with diversion of portal blood flowPrincipal Investigator

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Changes in Function of Hepatocyte Tight Junctions and Deal with Endotoxin by Hepatocytes after Hepatic ResectionPrincipal Investigator

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小腸移植後の神経系再構築における神経成長因子の役割Principal Investigator

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核DNA損傷度測定による肝切除における血流不良域の評価と処置法Principal Investigator

Principal Investigator

SATO Tsutomu 佐藤勤