SHIRAYOSHI Yasuaki 白吉安昭

… Alternative Names

白吉保昭シラヨシヤスアキ

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Researcher Number	90249946
Affiliation (Current)	2025: 鳥取大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 鳥取大学, 医学部, 准教授 2011 – 2019: 鳥取大学, 医学(系)研究科(研究院), 准教授 2015 – 2016: 鳥取大学, 医学系研究科, 准教授 2014: 鳥取大学, 医学研究科, 准教授 2012: 鳥取大学, 医学研究科, 准教授 … More 2007 – 2010: Tottori University, 大学院・医学系研究科, 准教授 2008: 鳥取大学, 医学系研究科, 准教授 2006: 鳥取大学, 大学院医学系研究科, 助教授 1997 – 2003: National Institute of Genetics, Mammalian Development Laboratory, Assistant Prof, 医学部, 助教授 2001: 鳥取大学, 医学部, 教授 1997: National Institute of Genetics, Genetic Strains Research Center, research associ, 系統生物研究センター, 助手 1992 – 1996: 国立遺伝学研究所, 遺伝実験生物保存研究センター, 助手 Less
Review Section/Research Field	Principal Investigator Developmental biology / Basic Section 48020:Physiology-related / Basic Section 90110:Biomedical engineering-related / General physiology / Regenerative medicine / Developmental biology / 遺伝 Except Principal Investigator Developmental biology / Cardiovascular medicine / General physiology … More / Biological Sciences / Basic Section 42040:Laboratory animal science-related / Studies on the Super-Aging Society / Basic Section 53020:Cardiology-related / Immunology / Circulatory organs internal medicine Less
Keywords	Principal Investigator ペースメーカ細胞 / 蛍光タンパク質 / イオンチャネル / ヒトiPS細胞 / 心筋 / Notch4 / 心筋細胞 / MLC2v / HCN4 / 可視化 … More / iPS細胞 / 幹細胞 / テラトカルシノーマ細胞 / 多能性 / 染色体 / ES細胞 / 細胞融合 / Notch / pacemaker cells / human iPS cells / cardiomyocytes / Patch-seq / 洞結節ペースメーカ細胞 / ヒト多能性幹細胞 / 分化誘導 / オルガノイド / 心臓前駆細胞 / 心外膜 / バイオテクノロジー / 生理学 / 再生医学 / MiRP1 / 心室筋細胞 / ゲノム編集 / ヒトiPS 細胞 / 洞結節ペースメーカ / MIRP1 / 先天性QT延長症候群 / 心室筋 / QT延長症候群 / 疾患iPS細胞 / Gene targeting / Endothelial cells / Hematopoietic stem cells / Stem cells / ジーンターゲッティング / 造血幹細胞 / ジーンターゲティング / 血管内皮細胞 / 造血細胞 / HCN4イオンチャネル / CRISPR/Cas9 / 心筋分化誘導 / ペースメーカ細部 / 再生医療 / 心筋分化 / ヒトES細胞 / 分化能 / 胚性幹細胞 / プロテオーム / クロマチン / 未分化性 / 細胞分化 / 初期化 / 分化抑制因子 / 多分化能 / 神経発生 / int-3 … More Except Principal Investigator 始原生殖細胞 / マウス / 遺伝子導入 / 生殖細胞 / 胎仔生殖細胞 / 細胞外マトリックス / HCN4 / 性分化 / アポトーシス / 主要組織適合性抗原遺伝子群 / テネイシン・ファミリー / テネイシンX / テネイシン / iPS細胞 / iPS cell / ペースメーカ細胞 / 自動能 / ES細胞 / モデルマウス / 卵巣 / 精巣 / EG細胞株 / 増殖因子 / 細胞増殖 / 神経細胞 / iPS / CD133 / primordial germ cells / mouse / 減数分裂 / gp130 / ヒトiPS細胞 / イオンチャネル / ペースメーカ / 染色体導入 / ヒト21番染色体 / 転写因子 / 雌雄分化 / サイトカインレセプター / ジーン・ターゲティング / トランスジェニックマウス / 細胞培養 / がん遺伝子 / マウスモデル / 遺伝子組換え / 光照射 / 疾患モデル / 不整脈 / 光操作型Cre組換え酵素 / 光遺伝学 / 老化関連分泌現象 / 老化 / 健康寿命 / SASP / セノセラピー / 細胞老化 / マクロファージ貪食能 / ラット由来心筋細胞 / 老化ヒト心筋細胞 / SASP因子 / feature value / sinus nodal cell / machine learning / 特徴量 / 形態 / 機械学習 / 洞結節細胞 / 深層学習 / SAN cell / automaticity / deep learning / sinoatrial node / 幹細胞 / 刺激伝導系細胞 / ペースメーカ幹細胞 / human / pacemaker cell / isl1 / progenitor / biological pacemaker / 選別分取 / 心臓 / 再生医学 / Ifチャネル / ヒトES/iPS細胞 / CDM / transferin receptor / differentiation / ES cells / human chromosome / human melanoma specific antibody / TC mice / がん診断・治療 / ヒト染色体特異的抗体 / ヒト抗体ライブラリー / 微小核細胞融合法 / 細胞免疫染色 / ヒト染色体 / B16-F10 / 医薬品探索 / 分化マーカー / ヒト細胞表面抗原 / ヒトメラノーマ特異的抗体 / ヒト抗体産生マウス / cell culture / ovary / testis / meiosis / sex differentiation / 配偶子分化 / EC細胞株 / major histocompatibility complex (MHC) / tenascin family / tenascinX / extraccllular matrix / 主要組織適合性抗原遺伝子 / transgenic mouse / spermatocyte / artificial fertilization / EG cells / apoptosis / gene transfection / 細胞融合 / 顕微注入 / 精子細胞 / 体外受精 / 胚移植 / 生殖巣 / 精母細胞 / 顕微受精 / EG細胞 / Chimeric Mouse / ES cell / CpG island / Gene Knockout / Tenascin-R / Tenascin-X / Tenascin-C / Extracellular Matrix / キメラマウス / CpGアイランド / 遺伝子破壊 / テネイシン-R / テネイシン-X / テネイシン-C / Retinoic acid / Tunor necrosis factor / Apoptosis / Gene transfection / EG cell lines / Fatal germ cells / Primordial germ cells / TNF-alpha / 発生工学 / TNF-α / レチノイン酸 / TNE-α / HSP70 / 疾患iPS細胞 / ion channel / LQT / 熱ショック蛋白 / LQT1 / 疾患iiPS / protein quality control / chaperone / histone deacetylase 10 / Histone deacetylase 6 / histine deacetylase / mutant hERG / mutation / histone deacetylase / HDAC阻害剤 / HDAC6 / ユビキチン化 / アセチル化 / 変異hERG / lysine / ubiquitination / acetylation / histone deacetylase 6 / hERG / LQT2 / ヒトＥＳ細胞 / HCN4搭載BACベクター / ヒトES細胞 / pacemaking cells / human ES cells / 細胞移植 / 房室ブロックモデル / 生物学的ペースメーカ / 遺伝子量効果 / ダウン症候群 / ミオシン蛋白質 / 組織特異性 / 遺伝子発現 / 心奇形 / 行動異常 / ダウン症 / 滅数分裂 / 性決定 / アポートシス / 脳神経系発生 / 胎仔手術 / 不死化がん遺伝子 / グリア細胞 / 細胞株樹立 / 神経幹細胞 / がん浸潤・転移 / ジーン・ターゲテイング / 心筋 / ジーン・タ-デティング / 神経発生 / 細胞分化 / マウス胚子 / 胚幹細胞 Less

Patch-seqを用いた包括的解析によるiPS細胞由来心筋の解析Principal Investigator
- Principal Investigator
  
  白吉安昭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Tottori University
光操作を用いた不整脈モデル動物の創出による心臓拍動制御メカニズムの解明
- Principal Investigator
  
  森川久未
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double positive cells differentiated from human iPS cells
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Development of basic technology for the production of cardiac organoids derived from human pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  SHIRAYOSHI Yasuaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Tottori University
健康寿命の延伸に向けた再生医療技術によるヒト心筋細胞の老化関連分泌現象の解明
- Principal Investigator
  
  三明淳一朗
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Tottori University
Elucidation of the pathophysiology and etiology of congenital long QT syndrome type 6 by myocardial cell screening and iPS technologyPrincipal Investigator
- Principal Investigator
  
  SHIRAYOSHI Yasuaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tottori University
Development of progenitors of bioogical pacemaker from human iPS cells
- Principal Investigator
  
  Hisatome Ichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Evaluation of cardiac automaticity using human cardiac pacemaking cells derived from human embryonic stem/ induced pluripotent stem cells
- Principal Investigator
  
  Morikawa Kumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Fluorescent reporter lines in human iPS cells offer useful platforms to study cardiac subtype specification, cell-based therapies of cardiac disease and drug development.Principal Investigator
- Principal Investigator
  
  Shirayoshi Yasuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Tottori University
The role of Hsp70 in quality control of mutant hERG protein associated LQT2 and its therapeutic application.
- Principal Investigator
  
  Li Peili
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Stabilization of KvLQT1 by Hsp70 in differentiiated cardiomyocytes derived from LQT1 iPS cells
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tottori University
Establishment of human pluripotent stem cell-derived pace-making cells using physiological approach and its application to the regenerative medicine
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tottori University
Establishment of ES cell-derived biological pacemaker using ion channel and its application to bradycardia arrhythmias
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
Analysis of regulatory mechanism on potency and maintenance of undifferentiated state in undifferentiated stem cells.Principal Investigator
- Principal Investigator
  
  SHIRAYOSHI Yasuaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Tottori University
細胞融合法を用いた初期化と未分化状態の維持に関与する原因染色体の同定Principal Investigator
- Principal Investigator
  
  白吉安昭
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  遺伝
- Research Institution
  Tottori University
ヒト21番染色体を保持するダウン症候群モデルマウスの作出とその原因遺伝子同定
- Principal Investigator
  
  押村光雄
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tottori University
Generation of human chromosome-specific monoclonal antibodies using trans-chromosomic (TC) mice
- Principal Investigator
  
  OSHIMURA Mitsuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Tottori University
ヒト21番染色体を保持するダウン症候群モデルマウスの作出とその原因遺伝子同定
- Principal Investigator
  
  OSHIMURA Mitsuo
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tottori University
マウス胎仔生殖細胞の分化制御機構に関する研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
The regulatory mechanisms of self-proliferation and differentiation in stem cellsPrincipal Investigator
- Principal Investigator
  
  SHIRAYOSHI Yasuaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Tottori University
マウス胎仔生殖細胞の分化制御機構に関する研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
マウス胎仔生殖細胞の分化制御機構に関する研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Research on regulation mechanisms of development and differentiation of mouse primordial germ cells
- Principal Investigator
  
  NAKATSUJI Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
がん遺伝子導入マウス胚由来の神経系幹細胞の増殖・分化に関する研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
新しく見い出した細胞外マトリックス蛋白質のがん浸潤と転移への関与についての研究
- Principal Investigator
  
  松本健一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
マウス胎仔生殖細胞の分化制御機構に関する研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Study on ECM tenascin-family proteins by gene knockout
- Principal Investigator
  
  IKEMURA Toshimichi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  NATIONAL INSTITUTE OF GENETICS
Research on manipulation of mammalian fetal germ cells and gene transfection
- Principal Investigator
  
  NAKATSUJI Norio
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
Studies on extracellular matrix tenascin family
- Principal Investigator
  
  MATSUMOTO Ken-ichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
心筋で高い発現をする細胞外マトリックスTN-Xの心筋の発生・分化における役割
- Principal Investigator
  
  MATSUMOTO Ken-ichi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
新しく見い出した細胞外マトリックス蛋白質のがん浸潤と転移への関与についての研究
- Principal Investigator
  
  松本健一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
マウス神経系の初期発生を制御する遺伝子クローニングの試みPrincipal Investigator
- Principal Investigator
  
  白吉安昭
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
マウス神経幹細胞へのがん遺伝子導入による細胞増殖・分化の研究
- Principal Investigator
  
  中辻憲夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
Research on control mechanisms of growth and differentiation of mouse primordial germ cells and their developmental manipulation
- Principal Investigator
  
  NAKATSUJI Norio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
マウス胚幹細胞へのがん遺伝子導入による細胞増殖・分化の研究
- Principal Investigator
  
  NAKATSUJI Norio
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics

[Journal Article] Inhibition of the uric acid efflux transporter ABCG2 enhances stimulating effect of soluble uric acid on IL-1β production in murine macrophage-like J774.1 cells2023
- Author(s)
  Notsu Tomomi、Kurata Yasutaka、Ninomiya Haruaki、Taufiq Fikri、Komatsu Koji、Miake Junichiro、Sawano Tatsuya、Tsuneto Motokazu、Shirayoshi Yasuaki、Hisatome Ichiro
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 10 Pages: 2368-2377
- DOI
  10.1038/s41440-023-01391-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-23K10826
[Journal Article] Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double-positive cells differentiated from human iPS cells2023
- Author(s)
  Wakimizu T, Naito J, Ishida M, Kurata Y, Tsuneto M, Shirayoshi Y, Hisatome I.
- Journal Title
  
  J. Arrhythm
  
  Volume: 39 Issue: 4 Pages: 664-668
- DOI
  10.1002/joa3.12883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06335, KAKENHI-PROJECT-20K12623
[Journal Article] SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation.2022
- Author(s)
  Wakimizu T, Morikawa K, Fukumura K, Yuki T, Adachi T, Kurata Y, Miake J, Hisatome I, Tsuneto M, Shirayoshi Y.
- Journal Title
  
  Regen Ther.
  
  Volume: 21 Pages: 239-249
- DOI
  10.1016/j.reth.2022.07.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12623, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K08423, KAKENHI-PROJECT-22K06979
[Journal Article] Esm1 and Stc1 as Angiogenic Factors Responsible for Protective Actions of Adipose-Derived Stem Cell Sheets on Chronic Heart Failure After Rat Myocardial Infarction2021
- Author(s)
  Watanabe Mai、Horie Hiromu、Kurata Yasutaka、Inoue Yumiko、Notsu Tomomi、Wakimizu Takayuki、Adachi Maya、Yamamoto Kenshiro、Morikawa Kumi、Kuwabara Masanari、Sakaguchi Takuki、Morisaki Takayuki、Miake Junichiro、Nishimura Motonobu、Tsuneto Motokazu、Shirayoshi Yasuaki、Ito Shin、Kitakaze Masafumi、et al.
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 5 Pages: 657-666
- DOI
  10.1253/circj.CJ-20-0877
- NAID
  130008028975
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-04-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-18K08757, KAKENHI-PROJECT-21K08844, KAKENHI-PROJECT-20K20662
[Journal Article] Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock2020
- Author(s)
  Otani Naoyuki、Kurata Yasutaka、Maharani Nani、Kuwabara Masanari、Ikeda Nobuhito、Notsu Tomomi、Li Peili、Miake Junichiro、Yoshida Akio、Sakaguchi Hiromi、Higaki Katsumi、Nakasone Naoe、Tsuneto Motokazu、Shirayoshi Yasuaki、Ouchi Motoshi、Ninomiya Haruaki、Yamamoto Kazuhiro、Anzai Naohiko、Hisatome Ichiro
- Journal Title
  
  Circulation Reports
  
  Volume: 2 Issue: 8 Pages: 425-432
- DOI
  10.1253/circrep.cr-20-0016
- NAID
  130007885744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-18K08074
[Journal Article] Pretreatment with cilnidipine attenuates hypoxia/reoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening2020
- Author(s)
  Minato Hiroyuki、Hisatome Ichiro、Kurata Yasutaka、Notsu Tomomi、Nakasone Naoe、Ninomiya Haruaki、Hamada Toshihiro、Tomomori Takuya、Okamura Akihiro、Miake Junichiro、Tsuneto Motokazu、Shirayoshi Yasuaki、Endo Ryo、Otsuki Akihiro、Okada Futoshi、Inagaki Yoshimi
- Journal Title
  
  Hypertension Research
  
  Volume: 43 Issue: 5 Pages: 380-388
- DOI
  10.1038/s41440-019-0391-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-17K08761, KAKENHI-PROJECT-20K20662
[Journal Article] Novel dual-reporter transgenic rodents enable cell tracking in animal models of stem cell transplantation2019
- Author(s)
  Morikawa K, Nakamura K, Suyama Y, Yamamoto K, Fukuoka K, Yagi S, Shirayoshi Y, Ohbayashi T, Hisatome I.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 18 Pages: 100645-100645
- DOI
  10.1016/j.bbrep.2019.100645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K11539
[Journal Article] Inhibitory effects of class I antiarrhythmic agents on Na+ and Ca2+ currents of human iPS cell-derived cardiomyocytes.2019
- Author(s)
  Yonemizu S, Masuda K, Kurata Y, Notsu T, Higashi Y, Fukumura K, Li P, Ninomiya H, Miake J, Tsuneto M, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Regen Ther.
  
  Volume: 10 Pages: 104-111
- DOI
  10.1016/j.reth.2018.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-18K08074
[Journal Article] Restoration of mutant hERG stability by inhibition of HDAC62018
- Author(s)
  Li Peili、Kurata Yasutaka、Endang Mahati、Ninomiya Haruaki、Higaki Katsumi、Taufiq Fikri、Morikawa Kumi、Shirayoshi Yasuaki、Horie Minoru、Hisatome Ichiro
- Journal Title
  
  J mol Cell cardiol
  
  Volume: 115 Pages: 158-169
- DOI
  10.1016/j.yjmcc.2018.01.009
- NAID
  120007170666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-15K08277, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K08074
[Journal Article] Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction2018
- Author(s)
  Yamamoto Kenshiro、Kurata Yasutaka、Inoue Yumiko、Adachi Maya、Tsuneto Motokazu、Miake Junichiro、Ogino Kazuhide、Ninomiya Haruaki、Yoshida Akio、Shirayoshi Yasuaki、Suyama Yoshiko、Yagi Shunjiro、Nishimura Motonobu、Yamamoto Kazuhiro、Hisatome Ichiro
- Journal Title
  
  Regenerative Therapy
  
  Volume: 9 Pages: 79-88
- DOI
  10.1016/j.reth.2018.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09436, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-17K11539, KAKENHI-PROJECT-16K11367
[Journal Article] Isolation and characterization of ventricular-like cells derived from NKX2-5 eGFP/w and MLC2v mCherry/w double knock-in human pluripotent stem cells2018
- Author(s)
  Yamauchi Kaori、Li Junjun、Morikawa Kumi、Liu Li、Shirayoshi Yasuaki、Nakatsuji Norio、Elliott David A.、Hisatome Ichiro、Suemori Hirofumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 1278-1284
- DOI
  10.1016/j.bbrc.2017.11.133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K09580
[Journal Article] Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells2017
- Author(s)
  Onohara, Takeshi; Hisatome, Ichiro; Kurata, Yasutaka; Li, Peili; Notsu, Tomomi; Morikawa, Kumi; Otani, Naoyuki; Yoshida, Akio; Iitsuka, Kazuhiko; Kato, Masaru; Miake, Junichiro; Ninomiya, Haruaki; Higaki, Katsumi; Shirayoshi, Yasuaki; Nishihara, Takashi; Itoh, Toshiyuki; Nakamura, Yoshinobu; Nishimura, Motonobu
- Journal Title
  
  J. Arrhythmia,
  
  Volume: 32 Issue: 3 Pages: 226-233
- DOI
  10.1016/j.joa.2016.09.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241030, KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-15K08277
[Journal Article] <b>Tbx18-positive cells differentiated from murine ES cells serve as proepicardial progenitors to give rise to vascular smooth muscle cells and fibr</b><b>oblasts </b>2017
- Author(s)
  IKEDA Nobuhito、NAKAZAWA Natsumi、KURATA Yasutaka、YAURA Hisako、TAUFIQ Fikri、MINATO Hiroyuki、YOSHIDA Akio、NINOMIYA Haruaki、NAKAYAMA Yuji、KUWABARA Masanari、SHIRAYOSHI Yasuaki、HISATOME Ichiro
- Journal Title
  
  Biomed. Res.
  
  Volume: 38 Issue: 4 Pages: 229-238
- DOI
  10.2220/biomedres.38.229
- NAID
  130005966981
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-15K06896, KAKENHI-PROJECT-15K08277
[Journal Article] Prion Protein and Stage Specific Embryo Antigen 1 as Selection Markers to Enrich the Fraction of Murine Embryonic Stem Cell-Derived Cardiomyocytes.2016
- Author(s)
  Ikeda N, Nakayama Y, Nakazawa N, Yoshida A, Ninomiya H, Shirayoshi Y.
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 59 Pages: 126-134
- NAID
  120005775321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26501003
[Journal Article] M3 Muscarinic Receptor Signaling Stabilizes a Novel Mutant Human Ether-a-Go-Go-Related Gene Channel Protein via Phosphorylation of Heat Shock Factor 1 in Transfected Cells2016
- Author(s)
  Mahati E., Li P., Kurata Y., Maharani N., Nobuhito I., Sakata S., Ogura K., Miake J., Aiba T., Shimizu W., Nakasone N., Ninomiya H., Higaki K., Yamamoto K., Nakai A., Shirayoshi Y., Hisatome I.
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 12 Pages: 2443-2452
- DOI
  10.1253/circj.CJ-16-0712
- NAID
  130005284978
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-26501003
[Journal Article] Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1.2016
- Author(s)
  Kondo T., Hisatome I., Yoshimura S., Mahati E., Notsu T., Li P., Iitsuka K., Kato M., Ogura K., Miake J., Aiba T., Shimizu W., Kurata Y., Sakata S., Nakasone N., Ninomiya H., Nakai A., Higaki K., Kawata Y., Shirayoshi Y., Yoshida A., Yamamoto K.
- Journal Title
  
  Journal of Arrhythmia
  
  Volume: 32 Issue: 5 Pages: 433-440
- DOI
  10.1016/j.joa.2015.10.005
- NAID
  120007146982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-26501003
[Journal Article] 生物学的ペースメーカの展望2016
- Author(s)
  森川久未, 白吉安昭, 久留一郎.
- Journal Title
  
  心電図
  
  Volume: 34(4) Pages: 264-268
- NAID
  130005139479
- Data Source
  KAKENHI-PROJECT-15K21170
[Journal Article] Electrophysiological Properties of iPS Cell-Derived Cardiomyocytes from a Patient with Long QT Syndrome Type 1 Harboring the Novel Mutation M437V of KCNQ12016
- Author(s)
  Tatsufumi Sogo; Kumi Morikawa; Yasutaka Kurata; Peili Li; Takafumi Ichinose; Shinsuke Yuasa; Daizou Nozaki; Junichiro Miake, Haruaki Ninomiya, Wataru Shimizu, Keiichi Fukuda, Kazuhiro Yamamoto, Yasuaki Shirayoshi and Ichiro Hisatome.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 4 Pages: 9-17
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26501003
[Journal Article] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring the novel mutation M437V of KCNQ12016
- Author(s)
  Sogo T, Morikawa K, Kurata Y, Li P, Ichinose T, Yuasa S, Nozaki D, Miake J, Ninomiya H, Shimizu W, Fukuda K, Yamamoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 4 Pages: 9-17
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21170
[Journal Article] 生物学的ペースメーカの展望2016
- Author(s)
  森川久未、白吉安昭、久留一郎
- Journal Title
  
  心電図
  
  Volume: 35 Pages: 264-268
- NAID
  130005139479
- Data Source
  KAKENHI-PROJECT-26501003
[Journal Article] Stabilization of Kv1.5 channel protein by the inotropic agent olprinone.2015
- Author(s)
  Endo R, Kurata Y, Notsu T, Li P, Morikawa K, Kondo T, Ogura K, Miake J, Yoshida A, Shirayoshi Y, Ninomiya H, Higaki K, Kuwabara M, Yamamoto K, Inagaki Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 765 Pages: 488-494
- DOI
  10.1016/j.ejphar.2015.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-25461109
[Journal Article] Carvedilol Suppresses Apoptosis and Ion Channel Remodelling of HL-1 Cardiac Myocytes Expressing E334K cMyBPC.2015
- Author(s)
  Endo R, Bahrudin U, Notsu T, Tanno S, Onohara T, Yamaguchi S, Ikeda N, Surastri B, Nakayama Y, Ninomiya H, Shirayoshi Y, Inagaki Y, Yamamoto K, Yoshida A, Hisatome I.
- Journal Title
  
  Drug Res (Stuttg).
  
  Volume: 66 Issue: 03 Pages: 126-129
- DOI
  10.1055/s-0035-1555772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K06896
[Journal Article] P19 cells overexpressing Lhx1 differentiate into the definitive endoderm by recapitulating an embryonic developmental pathway.2015
- Author(s)
  Hasagawa A, Shirayoshi Y.
- Journal Title
  
  Yonago Acta medica
  
  Volume: 58 Pages: 15-22
- NAID
  120005596734
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26501003
[Journal Article] Molecular Mechanisms Underlying Urate-Induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes2015
- Author(s)
  Maharani N, Ting YK, Cheng J, Hasegawa A, Kurata Y, Li P, Nakayama Y, Ninomiya H, Ikeda N, Morikawa K, Yamamoto K, Makita N, Yamashita T, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 12 Pages: 2659-2668
- DOI
  10.1253/circj.CJ-15-0416
- NAID
  130005110934
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K15311, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-15H04823, KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-24390199
[Journal Article] E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells.2015
- Author(s)
  Li P, Kurata Y, Maharani N, Mahati E, Higaki K, Hasegawa A, Shirayoshi Y, Yoshida A, Kondo T, Kurozawa Y, Yamamoto K, Ninomiya H, Hisatome I.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 86 Pages: 138-146
- DOI
  10.1016/j.yjmcc.2015.07.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-25461109
[Journal Article] Instability of KCNE1-D85N that Causes Long QT Syndrome: Stabilization by Verapamil2014
- Author(s)
  Sakata S, Kurata Y, Li P, Notsu T, Morikawa K, Miake J, Higaki K, Yamamoto Y, Yoshida A, Shirayoshi Y, Yamamoto K, Horie M, Ninomiya H, Kanzaki S, Hisatome I.
- Journal Title
  
  Pacing Clinical Electrophysiology
  
  Volume: Epub ahead of print Issue: 7 Pages: 1-11
- DOI
  10.1111/pace.12360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591512, KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25461387, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134, KAKENHI-PROJECT-26501003
[Journal Article] Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers2013
- Author(s)
  Morikawa K, Ikeda N, Hisatome I, Shirayoshi Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 431(2) Pages: 225-31
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins2013
- Author(s)
  Iwai C, P Li,
- Journal Title
  
  Cardiovasc Res
  
  Volume: ３ Issue: 3 Pages: 520-528
- DOI
  10.1093/cvr/cvt200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25461387, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134
[Journal Article] Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers.2013
- Author(s)
  Morikawa K, Ikeda N, Hisatome I, Shirayoshi Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 431(2) Issue: 2 Pages: 225-31
- DOI
  10.1016/j.bbrc.2012.12.128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00001, KAKENHI-PROJECT-23659112, KAKENHI-PROJECT-25670110
[Journal Article] Simultaneous Treatment with Azelnidipine and Olmesartan Inhibits Apoptosis of Hl-1 Cardiac Myocytes Expressing E334k cMyBPC2013
- Author(s)
  Bahrudin U, Ikeda N, Utami SB, Maharani N, Morikawa K, Li P
- Journal Title
  
  Drug Res (Stuttg).
  
  Volume: １０ Issue: 10 Pages: 515-520
- DOI
  10.1055/s-0033-1347188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134
[Journal Article] Electrophysiological properties of prion-positive cardiac progenitors derived from murine embryonic stem cells.2012
- Author(s)
  Fujii H, Ikeuchi Y, Kurata Y, Ikeda N, Bahrudin U, Li P, Nakayama Y, Endo R, Hasegawa A, Morikawa K, Miake J,Yoshida A, Hidaka K, Morisaki T, Ninomiya H, Shirayoshi Y, Yamamoto K, Hisatome I.
- Journal Title
  
  Circ J.
  
  Volume: 76(12) Pages: 2875-83
- NAID
  10031126061
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone2012
- Author(s)
  Suzuki S, Kurata Y, Li P, Notsu T, Hasegawa A, Ikeda N, Kato M, Miake J, Sakata S, Shiota G, Yoshida A, Ninomiya H, Higaki K, Yamamoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 696(1-3) Pages: 28-34
- NAID
  10027704706
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction2011
- Author(s)
  Bahrudin U, Morikawa K, Takeuchi A, Kurata Y, Miake J, Mizuta E, Adachi K, HigakiK, Yamamoto Y, Shirayoshi Y, Yoshida A, Kato M, Yamamoto K, Nanba E, Morisaki H, Morisaki T, Matsuoka S, Ninomiya H, Hisatome I.
- Journal Title
  
  J Mol Biol
  
  Volume: 413(4) Pages: 857-78
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Transcriptional activation of SAP97 by HSF-1 stabilizes Kv1.5 in HL-1 cells2011
- Author(s)
  YK Ting, K Morikawa, Y Kurata, PL Li, U Bahrudin, E Mizuta, M Kato,J Miake, Y Yamamoto, A Yoshida, M Murata, T Inoue, A Nakai, G Shiota, K Higaki, E Nanba, H Ninomiya, Y Shirayoshi, I Hisatome.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 162(8) Pages: 1832-1842
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels2011
- Author(s)
  Urashima T, Kurata Y, Miake J, Kato M, Ogura K, Yano A, Adachi M, Tanaka Y, Yamada K, Hamada T, Mizuta E, Kuwabara M, Kato M, Yamamoto Y, Ogino K, Yoshida A, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biomed Res
  
  Volume: 32(5) Pages: 303-12
- NAID
  130004724056
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Novel effects of extracts from poisonous mushrooms on expression and function of the human ether-a-go-go-related gene channel.2011
- Author(s)
  Li P, Tanaka S, Ichiyanagi T, Ninomiya H, Ting Y, Utami SB, Aimi T, Shirayoshi Y, Miake J, Hisatome I.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34(9) Pages: 1474-80
- NAID
  130001872443
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Reciprocal Control of hERG Stability by Hsp70 and Hsc70 with Implication for Restoration of LQT2 Mutant Stability2011
- Author(s)
  Peili Li, Haruaki Ninomiya, Yasutaka Kurata, Masaru Kato, Junichiro Miake, Yasutaka Yamamoto, Osamu Igawa, Akira Nakai, Katsumi Higaki, Futoshi Toyoda, Jie Wu, Minoru Horie, Hiroshi Matsuura, Akio Yoshida, Yasuaki Shirayoshi, Masayasu Hiraoka, Ichiro Hisatome.
- Journal Title
  
  Circ Res.
  
  Volume: 108(4) Pages: 458-68
- NAID
  130002130408
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Reciprocal Control of hERG Stability by Hsp70 and Hsc70 with Implication for Restoration of LQT2 Mutant Stability2010
- Author(s)
  Peili Li, Haruaki Ninomiya, Yasutaka Kurata, Masaru Kato, Junichiro Miake, Yasutaka Yamamoto, Osamu Igawa, Akira Nakai, Katsumi Higaki, Futoshi Toyoda, Jie Wu, Minoru Horie, Hiroshi Matsuura, Akio Yoshida, Yasuaki Shirayoshi, Masayasu Hiraoka, Ichiro Hisatome
- Journal Title
  
  Circ Res (in press)
- NAID
  130002130408
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Transcriptional activation of SAP97 by HSF-1 stabilizes Kv1.5 in HL-1 cells2010
- Author(s)
  YK Ting, K Morikawa, Y Kurata, PL Li, U Bahrudin, E Mizuta, M Kato, J Miake, Y Yamamoto, A Yoshida, M Murata, T Inoue, A Nakai, G Shiota, K Higaki, E Nanba, H Ninomiya, Y Shirayoshi, I Hisatome
- Journal Title
  
  British J Pharmacol (in press)
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Identification, isolation and characterization of HCN4-positive pacemaking cells derived from murine embryonic stem cells during cardiac differentiation2010
- Author(s)
  Morikawa K, Bahrudin U, Miake J, Igawa O, Kurata Y, Nakayama Y, Shirayoshi Y, Hisatome I
- Journal Title
  
  Pacing Clin Electrophysiol 33
  
  Pages: 290-303
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca^<2+> channels in the embryonic heart of mice2010
- Author(s)
  Mizuta E, Shirai M, Arakawa K, Hidaka K, Miake J, Ninomiya H, Kato M, Shigemasa C, Shirayoshi Y, Hisatome I, Morisaki T
- Journal Title
  
  Biomed Res 31
  
  Pages: 301-305
- NAID
  130004903809
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway.2009
- Author(s)
  Kawazoe S, Ikeda N, Miki K, Shibuya M, Morikawa K, Nakano S, Oshimura M, Hisatome I, Shirayoshi Y.
- Journal Title
  
  Dev Growth Differ. 51(2)
  
  Pages: 81-93
- NAID
  10025373749
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.2009
- Author(s)
  Koshida S, Kurata Y, Notsu T, Hirota Y, Kuang TY, Li P, Bahrudin U, Harada S, Miake J, Yamamoto Y, Hoshikawa Y, Igawa O, Higaki K, Soma M, Yoshida A, Ninomiya H, Shiota G, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol. 604(1-3)
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases.2009
- Author(s)
  Yoshida A, Hisatome I, Taniguchi S, Shirayoshi Y, Yamamoto Y, Miake J, Ohkura T, Akama T, Igawa O, Shigemasa C, Kamijo K, Ikuyama S, Caturegli P, Suzuki K.
- Journal Title
  
  J Clin Endocrinol Metab. 94(2)
  
  Pages: 442-448
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Changes of HCN gene expression and I(f) currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation.2008
- Author(s)
  Yano S, Miake J, Mizuta E, Manabe K, Bahrudin U, Morikawa K, Arakawa K, Sasaki N, Igawa O, Shigemasa C, Yamamoto Y, Morisaki T, Hidaka K, Kurata Y, Yoshida A, Shiota G, Higaki K, Ninomiya H, Lee JK, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biomed Res. 29(4)
  
  Pages: 195-203
- NAID
  130004470715
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines.2008
- Author(s)
  Hirota Y, Kurata Y, Kato M, Notsu T, Koshida S, Inoue T, Kawata Y, Miake J, Bahrudin U, Li P, Hoshikawa Y, Yamamoto Y, Igawa O, Shirayoshi Y, Nakai A, Ninomiya H, Higaki K, Hiraoka M, Hisatome I.
- Journal Title
  
  Biochem Biophys Res Commun. 372(3)
  
  Pages: 469-474
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] ES細胞から心筋細胞への分化の分子機序2007
- Author(s)
  白吉安昭, 久留一郎
- Journal Title
  
  アニテックス 19・1
  
  Pages: 14-20
- Data Source
  KAKENHI-PROJECT-18570201
[Journal Article] ES細胞から心筋細胞への分化の分子機序2007
- Author(s)
  白吉安昭、久留一郎
- Journal Title
  
  アニテックズ 19
  
  Pages: 14-14
- Data Source
  KAKENHI-PROJECT-18570201
[Journal Article] AMP deaminase 3 plays a critical role in remote reperfusion lung injury.
- Author(s)
  Li P, Ogino K, Hoshikawa Y, Morisaki H, Toyama K, Morisaki T, Morikawa K, Ninomiya H, Yoshida A, Hashimoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biochem Biophys Res Commun.
- Data Source
  KAKENHI-PROJECT-23659112
[Patent] 新規刺激伝導系細胞様細胞2018
- Inventor(s)
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Holder
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-062705
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K09580
[Patent] 新規刺激伝導系様細胞2018
- Inventor(s)
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Holder
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-062705
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08539
[Patent] 新規ペースメーカ2010
- Inventor(s)
  久留一郎、白吉安昭、三明淳一朗
- Industrial Property Rights Holder
  大学法人鳥取大学
- Filing Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-20590866
[Patent] 新規ペースメーカ2009
- Inventor(s)
  久留一郎、白吉安昭、三明淳一朗
- Industrial Property Rights Holder
  大学法人鳥取大学
- Industrial Property Number
  2009-226760
- Filing Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-20590866
[Presentation] Developmental fate and cellular characteristics exhibited by HCN4-positive cardiomyocytes derived from human iPS cells.2023
- Author(s)
  森川久未、足立隆、今川明梨、重永雅人、脇水孝之、久留一郎、經遠智一、白吉安昭
- Organizer
  The Cardiovascular Bioengineering Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06072
[Presentation] Developmental fate and cellular characteristics exhibited by HCN4-positive cardiomyocytes derived from human iPS cells.2023
- Author(s)
  Kumi Morikawa, Takashi Adachi, Akari Imagawa, Masato Shigenaga, Takayuki Wakimizu, Ichiro Hisatome, Motokazu Tsuneto, Yasuaki Shirayoshi
- Organizer
  CARDIOVASCULAR BIOENGINEERING (CVBE) SYMPOSIUM 2023, Kyoto, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06335
[Presentation] Developmental fate and cellular characteristics exhibited by HCN4-positive cardiomyocytes derived from human iPS cells.2023
- Author(s)
  Morikawa K, Adachi T, Imagawa A, Shigenaga M, Wakimizu T, Hisatome I, Tsuneto M, Shirayoshi Y.
- Organizer
  Cardiovascular Bioengineering (CVBE) Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] ヒトiPS細胞を用いた心臓前駆細胞の選択的分取法の開発と特性解析2022
- Author(s)
  重永雅人, 今川明梨, 谷本久実, 經遠智一, 白吉安昭
- Organizer
  第45回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] ヒトiPS細胞に由来するHCN4陽性心筋細胞のはっせい・分化能とその特性解析2021
- Author(s)
  谷本久実、足立隆、經遠智一、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞からの心臓洞結節ペースメーカ細胞の分取システムの構築2021
- Author(s)
  脇水孝之、經遠智一、白吉安昭、久留一郎
- Organizer
  心電学関連春期大会2021
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 心臓洞結節ペースメーカ細胞の分取、解析のためのヒトiPS 細胞株の作製2021
- Author(s)
  脇水孝之、足立隆、林裕也、経遠智一、白吉安昭、久留一郎
- Organizer
  第20回　日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] HCN4/Sox2遺伝子標識によるヒトiPS細胞からの心臓洞結節ペースメーカ細胞の分取システムの構築2021
- Author(s)
  脇水孝之、経遠智一、白吉安昭、久留一郎
- Organizer
  心電学関連春期大会2021
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞からの心臓洞結節ペースメーカ細胞の分取システムの構築2021
- Author(s)
  脇水孝之、経遠智一、白吉安昭、久留一郎
- Organizer
  心電学関連春季大会2021
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] 予定心臓領域特異的マーカー遺伝子の発現を可視化したIPS細胞株の樹立2021
- Author(s)
  重永雅人、今川明梨、經遠智一、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 心房細動関連遺伝子PRRX1のヒト心房筋様細胞における機能解析2021
- Author(s)
  幸哲夫、經遠智一、三明淳一郎、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] 予定心臓領域特異的マーカー遺伝子の発現を可視化したIPS細胞株の樹立2021
- Author(s)
  重永雅人、今川明梨、經遠智一、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] 心房細動関連遺伝子PRRX1のヒト心房筋様細胞における機能解析2021
- Author(s)
  幸哲夫、經遠智一、三明淳一郎、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞からの心臓洞結節ペースメーカ細胞の分取システムの構築2021
- Author(s)
  脇水孝之、經遠智一、白吉安昭、久留一郎
- Organizer
  心電学関連春期大会2021
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] ヒトiPS細胞に由来するHCN4陽性心筋細胞のはっせい・分化能とその特性解析2021
- Author(s)
  谷本久実、足立隆、經遠智一、久留一郎、白吉安昭
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] ヒトiPS 細胞から心臓ペースメーカ細胞への全分化過程の検討2020
- Author(s)
  脇水孝之、足立隆、林裕也、経遠智一、久留一郎、白吉安昭
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] ヒトiPS 細胞から心臓ペースメーカ細胞への全分化過程の検討2020
- Author(s)
  脇水孝之、足立隆、林裕也、経遠智一、久留一郎、白吉安昭
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 心臓洞結節ペースメーカ細胞の分取、解析のためのヒトiPS 細胞株の作製2020
- Author(s)
  脇水孝之、足立隆、林裕也、経遠智一、白吉安昭、久留一郎
- Organizer
  第20回　日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K12623
[Presentation] サブタイプ心筋の分取、解析のためのヒト多能性幹細胞の作製2019
- Author(s)
  足立隆、林裕也、脇水孝之、経遠智一、久留一郎、白吉安昭
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 心臓発生メカニズムの解明を目的とする新規hiPS細胞株の樹立と解析2019
- Author(s)
  増田啓一郎、米水彩香、東祐平、野津智美、経遠智一、久留一郎、白吉安昭
- Organizer
  第18回　日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] Selective isolation and analysis of cardiac progenitor cells derived from human iPS cells2018
- Author(s)
  Yuhei Higashi, Kenta Fukumura, Keiichiro Masuda, Sayaka Yonemizu, Ichiro Hisatome, Yasuaki Shirayoshi
- Organizer
  第41回日本分子生物学会年会　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] ヒトiPS細胞由来心筋（iCell CMs）の電気生理学的特性とClass 1群抗不整脈薬によるNa+ならびにCa2+ channel阻害効果2018
- Author(s)
  米水彩香、増田啓一郎、東祐平、福村健太、三明淳一郎、小倉一能、白吉安昭、山本一博、久留一郎
- Organizer
  第１７回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] ヒトiPS細胞由来HCN4陽性心筋の電気生理学的特性解析と薬剤応答性2018
- Author(s)
  白吉安昭、増田啓一郎、米水彩香、野津智美、久留一郎
- Organizer
  第45回　日本毒性学会学術年会　大阪国際会議場
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 心臓発生メカニズムの解明を目的とする新規hiPS細胞株の樹立と解析2018
- Author(s)
  東祐平、福村健太、増田啓一郎、米水彩香、宮城香乃望、足立隆、久留一郎、經遠智一、白吉安昭
- Organizer
  第4１回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] Selective isolation of cardiac progenitor cells derived from human iPS cells2018
- Author(s)
  Yasuaki Shirayoshi, kenta Fukumura, Yuhei Higashi, Kumi Morikawa, Motokazu Tsuneto, Ichiro Hisatome
- Organizer
  Weinstein Cardiovascular Development and Regeneration Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] ヒトiPS細胞由来心筋（iCell CMs）の電気生理学的特性とClass 1群抗不整脈薬によるNa+ならびにCa2+ channel阻害効果2018
- Author(s)
  増田啓一郎、米水彩香、東祐平、福村健太、三明淳一郎、小倉一能、白吉安昭、山本一博、久留一郎
- Organizer
  第65回日本不整脈心電学会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] 虚血性心不全モデルに対する脂肪幹細胞シートと心不全薬の併用効果の検討2017
- Author(s)
  山本堅士郎、丹野翔伍、足立真彩、森川久未、大月優樹、大谷直由、陶山淑子、八木俊路朗、荻野和秀、三明淳一朗、白吉安昭、山本一博、西村元延、久留一郎
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台、仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Selective isolation and analysis of cardiac progenitor cells derived from human iPS cells2017
- Author(s)
  Higashi Yuhei、Fukumura Kenta、Masuda Keiichiro、Yonemizu Sayaka、Hisatome Ichiro、Shirayoshi Yasuaki
- Organizer
  第40回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] Fluorescent human iPS reporter lines offer useful platforms to study cardiac subtype specification and cell-based therapies of cardiac disease.2017
- Author(s)
  Yasuaki Shirayoshi, Kenta Fukumura, Kumi Morikawa, Ichiro Hisatome
- Organizer
  ISSCR (International Society of Stem Cell Research) 2017 Annual Meeting
- Place of Presentation
  Boston, Boston Convention and Exhibition Center
- Year and Date
  2017-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Fluorescent Human iPS/ES Reporter Lines Offer the Opportunity to Track Cardiac Subtype Cells in Cell-based Therapies and Drug Development2017
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Kenta Fukumura, Ichiro Hisatome
- Organizer
  第81回　日本循環器学会学術集会
- Place of Presentation
  石川県立音楽堂他、金沢
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Fluorescent Human iPS/ES Reporter Lines Offer the Opportunity to Track Cardiac Subtype Cells in Cell-based Therapies and Drug Development.2017
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Kenta Fukumura, Ichiro Hisatome
- Organizer
  第81回　日本循環器学会学術集会
- Place of Presentation
  金沢, 石川県立音楽堂他
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Fluorescent human reporter lines offer useful platforms to study cardiac subtype specification and cell-based therapies of cardiac disease2017
- Author(s)
  Shirayoshi Yasuaki、Fukumura Kenta、Morikawa Kumi、Hisatome Ichiro
- Organizer
  ISSCR 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539
[Presentation] 虚血性心不全モデルに対する脂肪幹細胞シートと心不全薬の併用効果の検討2017
- Author(s)
  山本堅士郎、丹野翔伍、足立真彩、森川久未、大月優樹、大谷直由、陶山淑子、八木俊路朗、荻野和秀、三明淳一朗、白吉安昭、山本一博、西村元延、久留一郎
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Fluorescent human iPS reporter lines offer useful platforms to study cardiac subtype specification and cell-based therapies of cardiac disease.2017
- Author(s)
  Yasuaki Shirayoshi, Kenta Fukumura, Kumi Morikawa, Ichiro Hisatome
- Organizer
  ISSCR 2017
- Place of Presentation
  Boston, USA
- Year and Date
  2017-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] ヒトiPS細胞に由来する心筋前駆細胞の選別採取とその解析2017
- Author(s)
  東祐平、福村健太、増田啓一郎、米水彩香、久留一郎、白吉安昭
- Organizer
  第40回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] ヒトiPS細胞に由来するHCN4陽性心筋前駆細胞の解析2016
- Author(s)
  福村健太、横井文香、森川久未、野崎大蔵、久留一郎、白吉安昭
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  横浜, パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Stabilization of Kv1.5 Channel Protein by Olprinone as a Chemical Chaperone2016
- Author(s)
  Ryo Endo, Yasutaka Kurata, Peili Li, Kumi Morikawa, Takehito Kondo, Kazuyoshi Ogura, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] ヒトiPS細胞に由来するHCN4陽性心筋前駆細胞の解析2016
- Author(s)
  福村健太、横井文香、森川久未、野崎大蔵、久留一郎、白吉安昭
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] 選別純化したヒト多能性幹細胞由来分化誘導心筋に関する電気生理学的特性と薬剤応答性の評価2016
- Author(s)
  白吉安昭、森川久未、山内香織、横井文香、福村健太、野崎大蔵、末盛博文、久留一郎
- Organizer
  第43回　日本毒性学会
- Place of Presentation
  名古屋, ウインクあいち
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Electrophysiological Properties of iPS Cell-Derived Cardiomyocytes from a Patient with LQT1 Harboring the Novel Mutation M437V of KCNQ12016
- Author(s)
  Yasutaka Kurata, Peili Li, Kumi Morikawa, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Generation of Biological Pacemaker Derived fromHuman Pluripotent Stem Cells2016
- Author(s)
  白吉安昭
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2016-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Generation of Biological Pacemaker Derived from Human Pluripotent Stem Cells2016
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Junichiro Miake, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] 選別純化したヒト多能性幹細胞由来分化誘導心筋に関する電気生理学的特性と薬剤応答性の評価2016
- Author(s)
  白吉安昭、森川久未、山内香織、横井文香、福村健太、野崎大蔵、末盛博文、久留一郎
- Organizer
  第43回　日本毒性学会
- Place of Presentation
  ウインクあいち、名古屋
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Electrophysiological properties of iPS cell-derived cardiomyocytes from patients with long QT syndrome type 1 harvoring a novel mutation KCNQ1.2015
- Author(s)
  Yasutaka Kurata, Peili Li, Kumi Morikawa, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第３０回日本不整脈学会学術集会・第３２回日本心電学会学術集会合同学術大会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Isolation and Characterization of HCN4 positive cells derived from human embryonic stem cells2015
- Author(s)
  Kumi Morikawa, Nozaki Daizou, Yasuaki Shirayoshi, Ichiro Hisatome.
- Organizer
  ISSCR (International Society of Stem Cell Research) 13th Annual Meeting
- Place of Presentation
  STockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] HCN4 Positive Cells Derived from Pluripotent Stem Cells Show Automaticity and Pacemaking Ability2015
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Junichiro Miake, Ichiro Hisatome
- Organizer
  The79th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-04-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Stabiliation of Kv1.5 Channel Protein by Olprinone2015
- Author(s)
  Ryo Endo, Yasutaka Kurata, Peili Li, Kumi Moeikawa, Tatehito Kondo, Kazuyoshi Ogura, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第32回日本心電学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Isolation and Characterization of HCN4 positive cells derived from human embryonic stem cells2015
- Author(s)
  Kumi Morikawa, Nozaki Daizou, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  ISSCR (International Society of Stem Cell Research) 13th Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring a novel mutation of KCNQ12015
- Author(s)
  Yasutaka Kurata, Peili Li, Kumi Moeikawa, Junichiro Miake Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第32回日本心電学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] ヒト末梢血T細胞由来人工多能性幹(hTiPS)細胞の樹立と心筋分化誘導ならびにその特性解析2013
- Author(s)
  十川達文.三明淳一朗.山本 ―博.白吉安昭.久留一郎
- Organizer
  第103回日本循環器学会中国地方会
- Place of Presentation
  米子市　米子ビッグシップ
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] E3 ligase CHIP interacts with Hsc70 to regulate Kv1.5 expression and repolarization　in HL-1 cells2013
- Author(s)
  Peili Li, Masaru Kato, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第30回日本心電学会学術集会
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] イオンチャンネルを可視化選別マーカーとしたES細胞由来生物学的ペースメーカー細胞の樹立とその特性の検討2008
- Author(s)
  白吉安昭
- Organizer
  第25回日本心電学会学術集会
- Place of Presentation
  朱鷺メツセ(新潟)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-18570201
[Presentation] イオンチャンネルを可視化選別マーカーとしたES細胞由来生物学的ペースメーカー細胞の樹立とその特性の検討2008
- Author(s)
  白吉安昭
- Organizer
  第25回日本心電学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-18570201
[Presentation] Hsp90 Prevents Interaction between CHIP and HERG Proteins to Facilitate Maturation of Wild-type and Mutant HERG Proteins
- Author(s)
  Peili Li, Yasutaka Kurata, Nani Maharani, Yuko Ishido, Juichiro Miake, Yasuaki Shirayoshi, Kazuhiro Yamamoto, Ichiro Hisatome
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] Electrical properties of human iPS cell^derived cardiac myocytes from the patient with ling QT syndrome harboring a novel mutation of KCNQ1.
- Author(s)
  Sogo T, Ichinose T, Ikeda N, Shirayoshi Y, Morikawa K, Kurata Y, Miake J, Yamamoto K, Yuasa S, Fukuda K, Hisatome I.
- Organizer
  第29回日本不整脈学会、第31回日本心電図学会、合同学術大会
- Place of Presentation
  東京プリンスホテル、東京
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] Stabilization of A78T-HERG that Causes Long QT Syndrome Type2 by Heat Shock Protein Family
- Author(s)
  TakehitoKondo, JunichiroMiake, Kazuyoshi Ogura, Masaru Kato, Kazuhiko Iitsuka, Kazuhiro Yamamoto Yasuaki　Shirayoshi, Ichiro Hisatome.
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] Electrical properties of human iPS cell-derived cardiac myocytes from the patient with long QT syndrome harboring a novel mutation of KCNQ1.
- Author(s)
  十川達文、一ノ瀬貴史、森川久未、池田信人、白吉安昭、倉田康孝、三明淳一朗、山本一博、湯浅慎介、福田恵一、久留一郎
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] Isolation and Characterrization of HCN4 positive cells derived from human embryonic stem cells.
- Author(s)
  Morikawa K, Nozaki D, Shirayoshi Y, Hisatome I.
- Organizer
  International Society for Stem cell Rsearch 13th Annual Meeting
- Place of Presentation
  Stocjholm Sweden
- Year and Date
  2015-06-24 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-26501003
[Presentation] HCN4 positive cells derived from pluripotent stem cells show automaticity and pace making ability.
- Author(s)
  Shirayoshi Y, Morikawa K, Miake J, Hisatome I.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場等、大阪
- Year and Date
  2015-04-24 – 2015-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-26501003
[]

1. NAKATSUJI Norio (80237312)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
2. HISATOME Ichiro (60211504)

# of Collaborated Projects: 6 results

# of Collaborated Products: 43 results
3. IKEMURA Toshimichi (50025475)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. MATSUMOTO Ken-ichi (30202328)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. MIAKE Junichiro (40372677)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
6. Morikawa Kumi (90707217)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
7. Ikeda Nobuhito (50620316)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
8. OSHIMURA Mitsuo (20111619)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. Li Peili (40464292)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
10. 目黒牧子 (20304222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 經遠智一 (60730207)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
12. KATOH Motonobu (00273904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. YAMAMOTO Yasutaka (20362882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
14. OGURA Atsuo (20194524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HAYASHI Shinnichi (50208617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 海老原達彦 (00344119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. BIRD A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TOMIZUKA Kazuma

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAZAWA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. CHIQUETーEHRI エリスマンアール

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SHIRAYOSHI Y.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. CHIQUET-EHRISMANN R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MATSUMOTO K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 伊藤敏幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 中井彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 荻野和秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 神崎晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIRAYOSHI Yasuaki 白吉 安昭

白吉 保昭 シラヨシ ヤスアキ

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Co-Researchers

Patch-seqを用いた包括的解析によるiPS細胞由来心筋の解析Principal Investigator

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Development of basic technology for the production of cardiac organoids derived from human pluripotent stem cellsPrincipal Investigator

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Elucidation of the pathophysiology and etiology of congenital long QT syndrome type 6 by myocardial cell screening and iPS technologyPrincipal Investigator

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Fluorescent reporter lines in human iPS cells offer useful platforms to study cardiac subtype specification, cell-based therapies of cardiac disease and drug development.Principal Investigator

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Analysis of regulatory mechanism on potency and maintenance of undifferentiated state in undifferentiated stem cells.Principal Investigator

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SHIRAYOSHI Yasuaki 白吉安昭

白吉保昭シラヨシヤスアキ