YOSHIKAWA MASANOBU 吉川正信

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YOSHIKAWA Masanobu 吉川正信

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Researcher Number	90276791
External Links
Affiliation (Current)	2025: 東海大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2010 – 2025: 東海大学, 医学部, 准教授 2013: 東海大学, 医学部, 講師 2010: 東海大学, 医学部, 講師 2006 – 2008: 東海大学, 医学部, 講師 1995 – 2001: 東海大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Basic Section 57010:Oral biological science-related / Pathobiological dentistry/Dental radiology / Pain science Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology/Resuscitation studies / General pharmacology / Anesthesiology / Basic Section 42040:Laboratory animal science-related / General pharmacology / Orthodontic/Pediatric dentistry / Evolutionary biology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 唾液腺 / 唾液分泌 / 神経伝達物質 / マイクロダイアリシス / 自律神経 / 鎮静薬 / マイクリダイアリシス / 唾液腺マイクロダイアリシス / セロトニン / 抗うつ薬 … More / 中枢神経 / アセチルコリン / アミノ酸 / 口腔乾燥症 / Dメチオニン / 口腔領域障害 / 防護薬 / 唾液腺機能障害 / 放射線 / Dアミノ酸 / 神経細胞 / in situ hybridization / ベンゾジアゼピン / ミダゾラム / 下行性痛覚抑制経路 / 鎮痛作用 / NMDA受容体 / 耐性 / 鎮痛 / モルヒネ / セリンラセマーゼ / Dセリン / 疼痛学 … More Except Principal Investigator Dセリン / NMDA受容体 / 鎮痛 / セリンラセマーゼ / モルヒネ / 唾液腺 / シアロルフィン / 脊髄 / 疼痛 / in situ hybridization / D-セリン / 慢性疼痛 / Dアミノ酸 / グルタミン酸 / オピオイド受容体 / RT-PCR / Dアミノ酸酸化酵素 / ケタミン / 統合失調症 / ミューオピオイド受容体 / オピオイドペプチド / マイクロダイアリシス / 鎮痛耐性 / 下行性痛覚抑制経路 / 鎮痛作用 / ダイノルフィン / D体セリン / 神経障害性疼痛 / morphine-induced analgesia / モルヒネ鎮痛 / アンチセンスオリゴヌクレオチド / dynorphin / オピオイド / 活性酸素 / 耐性 / 神経細胞 / ベンゾジアゼピン / ミダゾラム / 精神症状 / 疼痛管理学 / ノックアウトマウス / アンチセンスオリゴDNA / 痛覚過敏 / ゲノム編集 / ラットモデル / カルシトニン遺伝子関連ペプチド（CGRP) / Srcファミリー / 自己炎症性骨疾患 / 神経障害生疼痛 / 興奮性アミノ酸 / 内因性ペプチド / 交感神経 / Dアミノ酸代謝 / モルヒネ誘発性疼痛 / ダサチニブ / Fgr / 骨破壊 / 骨痛モデル / 慢性再発性多発性骨髄炎（CRMO） / カルシトニン関連遺伝子ペプチド / 疾患モデル / Srcファミリーキナーゼ / 自己炎症 / 慢性再発性多発性骨髄炎 / グルタミン酸受容体 / 唾液腺マイクロダイアリシス / Dアミノ酸代謝酵素 / 麻酔薬 / 唾液分泌 / アロステリックモジュレーター / 内因性疼痛抑制系 / アロステリック / アロステリックモデュレーター / Ｄセリン / アストロサイト / 頭痛 / TRPM1 / 術後譫妄 / 譫妄 / NMDA / 酸化ストレス / せん妄 / Benzodiazepine receptor / NMDA receptor / Descending Analgesic System / D-amino acid oxidase / Serine racemase / morphine / Midazolam / D-serine / 脳室内投与 / 下行性抑制系路 / ベンゾジアゼピン受容体 / 下行性疼痛抑制経路 / Dアミノ酸オキシダーゼ / DNAzyme / ribozyme / antisense oligodeoxynucleotide / G protein α subunits / μ-opioid receptor / DNA酵素 / リボザイム / アンチセンスオリゴデオキシヌクレオチド / G蛋白質 / ニューオピオイド受容体 / opioid peptides / western blot / antisense oligodeoxynucleotides / G protein / mu-opioid receptor / G_<sα> / G_<0α> / G_<iα3> / G_<iα2> / G_<iα1> / in situ hvbridization / ウェスタンブロット / Gタンパク質 / モルヒネ慢性投与 / 鎮痛耐性形成 / TRPV1 / ガン性疼痛 / HIF-1 / 低酸素 / がん性疼痛 / cancer pain / toxicity / peptidase / 鎮痛効果 / セボフルラン / ヒスタチン / ダウン症候群 / 電子スピン共鳴法 / Down症候群 / プロテオーム / 唾液タンパク質 / 歯周病 / 術後痛 / Ｄアミノ酸酸化酵素 / 代謝 / Ataxia / 遺伝子発現 / 末梢神経 / 中枢 / ドーパミン / ニワトリ / DRD4 / DRD3 / DRD2 / ドーパミン受容体 / 家畜化 / 人為淘汰 / 分子系統樹 / 免疫組織化学 / 麻薬 / RNA干渉 / D-アミノ酸オキシダーゼ / 輸送体 / 線条体 / ドパミン / in vivo microdialysis / コカイン / ペチジン / アンチセンスDNA投与方法 / 遺伝子発現抑制 / 伝達物質不活性化機構 / ペプチド伝達物質 / ペプチダーゼ阻害剤 / ペプチダーゼ Less

内因性疼痛抑制系におけるプロホルモンSMR1の役割解明Principal Investigator
- Principal Investigator
  
  吉川正信
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Chronic recurrent multifocal osteomyelitis model animals for alleviation of bone pain
- Principal Investigator
  
  阿部幸一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokai University
オピオイド誘導性痛覚過敏におけるダイノルフィンとDセリンの相互作用
- Principal Investigator
  
  姜卓義
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
ダイノルフィンとD-セリンの脊髄疼痛伝達における相互作用に関する研究
- Principal Investigator
  
  渡邊真理子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
鎮静薬と唾液分泌に関する研究Principal Investigator
- Principal Investigator
  
  吉川正信
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Molecular dissection of bone pain using a mouse model for autoinflammatory disease
- Principal Investigator
  
  阿部幸一郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokai University
Effect of D-serine, a modulator of NMDA receptor activity, on morphine-induced pain
- Principal Investigator
  
  Matsuda Mitsumasa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Role of a new endogenous peptide, sialorphin, in pain control
- Principal Investigator
  
  Kan Takugi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Effects of D-body serine on spinal dorsal horn neuron modulation associated with neuropathic pain
- Principal Investigator
  
  Ito Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Studies on anesthesia and salivation
- Principal Investigator
  
  Watanabe Mariko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Effects of activated astrocyte-derived D-serine in neuropathic pain
- Principal Investigator
  
  Ito Kenji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Mechanism of morphine-induced pain
- Principal Investigator
  
  Matsuda Mitsumasa
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Sialorphin potentiates effects of opioid peptide without toxicity as alosteric modulator
- Principal Investigator
  
  KAN Takugi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokai University
Study of the effect of serotonin in the salivary glands on salivary secretion: using salivary gland microdialysis.Principal Investigator
- Principal Investigator
  
  Yoshikawa Masanobu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokai University
postoperative delirium and oxidative stess
- Principal Investigator
  
  TAKEYAMA Kazuhide
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Tokai University
Effects of D-serine on tolerance to the antinociceptive effects of morphine
- Principal Investigator
  
  ITO Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Tokai University
hypoxia in cancer pain
- Principal Investigator
  
  AJIMI Junko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Tokai University
D-methionine as a protector for irradiation-induced xerostomiaPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Masanobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokai University
The antinociceptive effect of sevoflurane
- Principal Investigator
  
  KANAZAWA Masahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Long-term treatment with morphine increases the D-serine content in the rat brain and spinal cord by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase
- Principal Investigator
  
  ITO Kenji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Elucidation of salivary antioxidant protein for prevention of periodontitis-Analysis of antioxidant property and proteome-
- Principal Investigator
  
  KOMATSU Tomoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kanagawa Dental College
Evolutionary Origin and Genetic Differentiation of Dopamine Receptor D2, D3 and D4 Genes of Japanese Domesticated Chickens
- Principal Investigator
  
  KOMIYAMA Tomoyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Tokai University
Identification of D-serine-related gene and elucidation of etiology of schizophrenia using genetically modified animals
- Principal Investigator
  
  HASHIMOTO Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University
The effects of the gene expression of D-serine related enzymes on psychiatric symptom induced by ketamine
- Principal Investigator
  
  TAKEYAMA Kazuhide
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Study for interaction between D-serine synthesis and development of morphine tolerance
- Principal Investigator
  
  ITO Kenji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Functional analysis of D-serine-metabolizing enzymes using RNA interference : Application to treatment of schizophrenia
- Principal Investigator
  
  HASHIMOTO Atsushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University
The relationship between psychosis induced by ketamine and D-serine synthesis
- Principal Investigator
  
  TAKEYAMA Kazuhide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Effect of administration of morphine on the synthesis of D-serine in rat brainPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Masanobu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tokai University
Study for effects of D-serine on antinociception induced by acute administration of morphine
- Principal Investigator
  
  ITO Kenji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Differential blockade of opioid analgesia by gene-specific therapeutics directed against various G protein α subnits
- Principal Investigator
  
  KOBAYASHI Hiroyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University
アンチセンスオリゴDNAを用いた脳内特定タンパク質の発現阻止に関する研究
- Principal Investigator
  
  岡哲雄
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokai University
Elucidation of cellular mechanism of mu-opioid receptor agonist-induced analgesia by employing antisense oligodeoxynucleotide
- Principal Investigator
  
  OKA Tetsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University
ミューオピオイド受容体に対するアンチセンスオリゴDNAの効果
- Principal Investigator
  
  岡哲雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University
オピオイドペプチドの遊離と不活性化阻害
- Principal Investigator
  
  OKA Tetsuo
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokai University

[Journal Article] D-Serine Increases Release of Acetylcholine in Rat Submandibular Glands2023
- Author(s)
  Yoshikawa M, Okubo M, Shirose K, Kan T, Kawaguchi M
- Journal Title
  
  Biology
  
  Volume: 12 Issue: 9 Pages: 1227-1240
- DOI
  10.3390/biology12091227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09053, KAKENHI-PROJECT-22K09102, KAKENHI-PROJECT-21K08931, KAKENHI-PROJECT-21K08955, KAKENHI-PROJECT-21K09004
[Journal Article] Free D-amino acids in salivary gland in rat2022
- Author(s)
  Yoshikawa M, Kan T, Shirose K, Watanabe M, Matsuda M, Ito K, Kawaguchi M
- Journal Title
  
  Biology
  
  Volume: 11 Issue: 3 Pages: 390-405
- DOI
  10.3390/biology11030390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08830, KAKENHI-PROJECT-18K08831, KAKENHI-PROJECT-18K09514, KAKENHI-PROJECT-19K09337, KAKENHI-PROJECT-21K08931, KAKENHI-PROJECT-21K08955, KAKENHI-PROJECT-21K09004
[Journal Article] The multi‐kinase inhibitor dasatinib suppresses autoinflammation and increases bone density in a mouse model for chronic recurrent multifocal osteomyelitis2021
- Author(s)
  Yoshikawa Ryo, Abe Koichiro
- Journal Title
  
  Cell Biochemistry and Function
  
  Volume: on line Issue: 4 Pages: 1-7
- DOI
  10.1002/cbf.3617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06041, KAKENHI-PROJECT-21K05991, KAKENHI-PROJECT-16H06276
[Journal Article] In Vivo Monitoring of Acetylcholine Release from Nerve Endings in Salivary Gland2021
- Author(s)
  Masanobu Yoshikawa and Mitsuru Kawaguchi
- Journal Title
  
  Biology
  
  Volume: 10 Issue: 5 Pages: 351-351
- DOI
  10.3390/biology10050351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09514
[Journal Article] Sialorphin potentiates effects of [Met5]enkephalin without toxicity by action other than peptidase inhibition2020
- Author(s)
  Takugi Kan, Masanobu Yoshikawa, Mariko Watanabe, Masaaki Miura, Kenji Ito, Mitsumasa Matsuda, Kayoko Iwao, HIroyuki Kobayashi, Takeshi Suzuki and Toshiyasu Suzuki
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 375 Issue: 1 Pages: 104-114
- DOI
  10.1124/jpet.120.266080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08869
[Journal Article] he effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the nephrotoxicity in the mouse during repeated cisplatin (CDDP) treatments2017
- Author(s)
  1. Yajima Y, Kawaguchi M, Yoshikawa M, Okubo M, Tsukagoshi E, Sato K, Katakura A
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Pages: 108-115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10546
[Journal Article] Effect of Peptidase Inhibitors on Dynorphin A (1-17) or (1-13)-Induced Antinociception and Toxicity at Spinal Level2017
- Author(s)
  Mitsumasa Matsuda, Masanobu Yoshikawa, Takugi Kan, Mariko Watanabe, Junko Ajimi, Shigeru Takahashi, Masaaki Miura, Kenji Ito, Hiroyuki Kobayashi, Toshiyasu Suzuki
- Journal Title
  
  Pharmacology & Pharmacy
  
  Volume: ８ Issue: 02 Pages: 33-51
- DOI
  10.4236/pp.2017.82003
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462385
[Journal Article] INHIBITION OF AMPA RECEPTORS AND ACTIVATION OF THE GLYCINE SITE OR POLYAMINE SITE OF NMDA RECEPTORS AT THE SUPRASPINAL LEVEL INDUCES ANTINOCICEPTION2017
- Author(s)
  Mitsumasa Matsuda, Masanobu Yoshikawa, Takugi Kan, Xing Lu Jin, Shigeru Takahashi, Hiroyuki Kobayashi and Tomoki Nishiyama
- Journal Title
  
  European Journal of Biomedical AND Pharmaceutical Sciences
  
  Volume: 4 Pages: 77-83
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462385
[Journal Article] Antinociceptive effect of intracerebroventricular administration of d-serine on formalin-induced pain2014
- Author(s)
  Ito M, Yoshikawa M, Ito K, Matsuda M, Jin X.L., Takahashi S, Kobayashi H, Suzuki T
- Journal Title
  
  J. Anesthesia
  
  Volume: 28 Pages: 228-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462932
[Journal Article] Increase in antinociceptive effect of [Leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors2014
- Author(s)
  Miura, M, Yoshikawa M, Watanabe M, Takahashi S, Ajimi J, Ito K, Ito M, Kawaguchi M, Kobayashi H, Suzuki T.
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 Pages: 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592359
[Journal Article] Antinociceptive effect of intracerebroventricular administration of d-serine on formalin-induced pain.2014
- Author(s)
  Ito M, Yoshikawa M, Ito K, Matsuda M, Jin X.L., Takahashi S, Kobayashi H, Suzuki T
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 28 Pages: 228-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Potentiation of [Met5]enkephalin-induced antinociception by mixture of three peptidase inhibitors in rat2014
- Author(s)
  Murata T, Yoshikawa M, Watanabe M, Takahashi S, Kawaguchi M, Kobayashi H, Suzuki T
- Journal Title
  
  J. Anesthesia
  
  Volume: 28 Issue: 5 Pages: 708-715
- DOI
  10.1007/s00540-014-1819-5
- Year and Date
  2014-04-05
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Methamphetamine-withdrawal stress activates PACAP-DBI pathway in rat salivary gland, resulting in inhibition of salivary secretion2014
- Author(s)
  Okubo M, Yoshikawa M, Shinomiya T, Kawaguchi M
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592359
[Journal Article] Antinociceptive effect of intracerebroventricular administration of d-serine on formalin-induced pain2014
- Author(s)
  Ito M, Yoshikawa M, Ito K, Matsuda M, Jin X.L., Takahashi S, Kobayashi H, Suzuki T
- Journal Title
  
  J. Anesthesia
  
  Volume: 28 Pages: 228-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592359
[Journal Article] Antinociceptive effect of intracerebroventricular administration of d-serine on formalin-induced pain2014
- Author(s)
  Ito M, Yoshikawa M, Ito K, Matsuda M, Jin X.L., Takahashi S, Kobayashi H, Suzuki T
- Journal Title
  
  J. Anesthesia
  
  Volume: 28(2) Pages: 228-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Methamphetamine-withdrawal stress activates PACAP-DBI pathway in rat salivary gland, resulting in inhibition of salivary secretion2013
- Author(s)
  Okubo M, Yoshikawa M, Shinomiya T, Kawaguchi M.
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462932
[Journal Article] Increase in antinociceptive effect of [Leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors2013
- Author(s)
  Miura, M, Yoshikawa M, Watanabe M, Takahashi S, Ajimi J, Ito K, Ito M, Kawaguchi M, Kobayashi H, Suzuki T
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 (2) Pages: 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] ncrease in antinociceptive effect of [Leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors2013
- Author(s)
  Miura, M, Yoshikawa M, Watanabe M, Takahashi S, Ajimi J, Ito K, Ito M, Kawaguchi M, Kobayashi H, Suzuki T
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 Pages: 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462932
[Journal Article] Methamphetamine-withdrawal stress activates PACAP-DBI pathway in rat salivary gland, resulting in inhibition of salivary secretion2013
- Author(s)
  Okubo M, Yoshikawa M, Shinomiya T, Kawaguchi M
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 (2) Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Increase in antinociceptive effect of [Leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors2013
- Author(s)
  Miura, M, Yoshikawa M, Watanabe M, Takahashi S, Ajimi J, Ito K, Ito M, Kawaguchi M, Kobayashi H, Suzuki T.
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 38 Pages: 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Pharmacological protection from radiation- and chemoradiation- induced oral mucositis2012
- Author(s)
  Cotrim P. A, Yoshikawa M, Sunshine N. A, Zheng C, Sowers L. A, Thetford D. A, Cook J. A, Mitchell B. J, Baum J. B
- Journal Title
  
  International Journal of Radiation Oncology Biology and Physics
  
  Volume: 83 (4) Pages: 1284-1290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Diazepam Enhances Production of Diazepam-Binding Inhibitor (DBI), a Negative Saliva Secretion Regulator, Localized in Rat Salivary Gland2011
- Author(s)
  Tsukagashi E., Shinomiya T., Yoshikawa M., et al
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 115 Pages: 221-229
- NAID
  10029892190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592026
[Journal Article] Proteomic Analysis of Lipopolysaccharide- treated Submandibular Gland in Rat2011
- Author(s)
  Sawaki K, Shinomiya T, Okubo M, Tsukagashi E, Ogane M, Matsuura M, Yoshikawa M, Kawaguchi M
- Journal Title
  
  Bulletin of Tokyo Dental College
  
  Volume: 52(1) Pages: 31-37
- NAID
  130004868647
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Diazepam Enhances Production of Diazepam-Binding Inhibitor(DBI), a Negative Saliva Secretion Regulator, Localized in Rat Salivary Gland2011
- Author(s)
  Tsukagoshi E, Shinomiya T, Yoshikawa M, Kawano T, Okubo M, Sawaki K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Pages: 221-229
- NAID
  10029892190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592026
[Journal Article] Diazepam Enhances Production of Diazepam-Binding Inhibitor (DBI), a Negative Saliva Secretion Regulator, Localized in Rat Salivary Gland2011
- Author(s)
  Tsukagoshi E, Kawaguchi M, Shinomiya T, Yoshikawa M, Kawano T, Okubo M, Sawaki K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Pages: 221-229
- NAID
  10029892190
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Subchronic administration of Ketamine decreases the mRNA expression of serine racemase in rat brain2010
- Author(s)
  M.Watanabe, M.Yoshikawa, K.Takeyama, et al
- Journal Title
  
  Tokai Journal of Experimental and Clinical Medicine
  
  Volume: 35 Pages: 137-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592026
[Journal Article] Subchronic administration of Ketamine decreases the mRNA expression of serine racemase in rat brain2010
- Author(s)
  M.Watanabe, M.Yoshikawa, K.Takeyama, et al
- Journal Title
  
  Tokai Journal of Experimental and Clinical Medicine
  
  Volume: 35 Pages: 137-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability2010
- Author(s)
  Nozaki M, Yoshikawa M, Ishitani K, Kobayashi H, Houkin K, Imai K, Ito Y, Muraki T
- Journal Title
  
  Keio J Med
  
  Volume: 59 Pages: 10-18
- NAID
  10026203480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592026
[Journal Article] Subchronic Administration of Ketamine Decreases the mRNA Expression of Serine Racemase in Rat Brain2010
- Author(s)
  Watanabe M, Yoshikawa M, Takeyama K, Hashimoto A, Kobayashi H, Suzuki T
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: 35(4) Pages: 137-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592026
[Journal Article] Subchronic administration of Ketamine decreases the mRNA exppresion of serine racemase in rat brain2010
- Author(s)
  Watamabe M., Yoshikawa M., Takeyama K., Hashimoto A., Kobayashi H. and Suzuki T.
- Journal Title
  
  Tokai J. Exp. Clin. Med
  
  Volume: 35 Pages: 137-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590292
[Journal Article] Inhibitory effect of low-dose pentazocine on the development of antinociceptive tolerance to morphine2009
- Author(s)
  Chiba S, Hayashida M, Yoshikawa M, Shu H, Nishiyama T, Yamada Y
- Journal Title
  
  J Anesthesia 23(1)
  
  Pages: 99-107
- NAID
  10025381744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The antinociceptive effects of midazolam on three different types of nociception in mice2009
- Author(s)
  Chiba S, Nishiyama T, Yoshikawa M, Yamada Y
- Journal Title
  
  J Pharmacol Sci 109(1)
  
  Pages: 71-77
- NAID
  10025733715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The antinociceptive effects of midazolam on three different types of nociception in mice2009
- Author(s)
  Masanobu Yoshikawa, et.al.
- Journal Title
  
  Journal of Pharmacological Sciences 109
  
  Pages: 71-77
- NAID
  10025733715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590292
[Journal Article] Inhibitory effect of low-dose pentazocine on the development of antinociceptive tolerance to morphine2009
- Author(s)
  Chiba S, Hayashida M, Yoshikawa M, Shu H, Nishiyama T, Yamada Y
- Journal Title
  
  J Anesthesia 23(1)
  
  Pages: 99-107
- NAID
  10025381744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] The antinociceptive effects of midazolam on three different types of nociception in mice2009
- Author(s)
  hiba S, Nishiyama T, Yoshikawa M, Yamada Y
- Journal Title
  
  J Pharmacol Sci 109(1)
  
  Pages: 71-77
- NAID
  10025733715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] The antinociceptive effects of midazolam on three different types of nociception in mice2009
- Author(s)
  Chiba S, Nishiyama T, Yoshikawa M, Yamada Y
- Journal Title
  
  J Pharmacol Sci 109(1)
  
  Pages: 71-77
- NAID
  10025733715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Inhibitory effect of low-dose pentazocine on the development of antinociceptive tolerance to morphine2009
- Author(s)
  Chiba S, Hayashida M, Yoshikawa M, Shu H, Nishiyama T, Yamada Y
- Journal Title
  
  J Anesthesia 23(1)
  
  Pages: 99-107
- NAID
  10025381744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] The serine racemase mRNA is expressed in both neurons and glial cells of rat retina2008
- Author(s)
  Takayasu N, Yoshikawa M, Watanabe M, Tsukamoto H, Suzuki T, Kobayashi H, Noda S
- Journal Title
  
  Arch Histol Cytol 71(2)
  
  Pages: 123-129
- NAID
  10025095752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Acute administration of methamphetamine decreases the mRNA expression of diazepam binding inhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Hashimoto A, Kawaguchi M, Bryne WD, Kobayashi H
- Journal Title
  
  Tokai J Exp Clin Med 33(1)
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  Yoshikawa M, Shinomiya T, Takayasu N, Tsukamoto H, Kawaguchi M, Kobayashi H, Oka T, Hashimoto A
- Journal Title
  
  J Pharmacol Sci 107(3)
  
  Pages: 270-276
- NAID
  10024321297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  Yoshikawa M, Shinomiya T, Takayasu N, Tsukamoto H, Kawaguchi M, Kobayashi H, Oka T, Hashimoto A
- Journal Title
  
  J Pharmacol Sci 107(3)
  
  Pages: 270-276
- NAID
  10024321297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition2008
- Author(s)
  Akahori K, Kosaka K, Jin XL, Arai Y, Yoshikawa M, Kobayashi H, Oka T
- Journal Title
  
  J Pharmacol Sci 106(2)
  
  Pages: 295-300
- NAID
  10024318545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Midazolam attenuates the antinociception induced by D-serine or morphine at the supraspinal level in rats.2008
- Author(s)
  Ito K., Yoshikawa M., Maeda M., Jin X.L., Takahashi S., Matsuda M., Tamaki R., Kobayashi H., Suzuki T., Hashimoto A.
- Journal Title
  
  morphine at the supraspinal level in rats. 586
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition2008
- Author(s)
  Akahori K, Kosaka K, Jin XL, Arai Y, Yoshikawa M, Kobayashi H, Oka T
- Journal Title
  
  J Pharmacol Sci 106(2)
  
  Pages: 295-300
- NAID
  10024318545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Acute administration of methamphetamine decreases the mRNA expression of diazepam binding expression of diazepam bindinginhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Hashimoto A, Kawaguchi M, Bryne WD, Kobayashi H
- Journal Title
  
  Tokai J Exp Clin Tokai J Exp Clin Med 33(1)
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Mice lacking D-amino acid oxidase activity exhibit marked reduction of methamphetamine -induced stereotypy2008
- Author(s)
  Hashimoto A, Konno R, Yano H, Yoshikawa M, Tamaki R, Matsumoto H, Kobayashi H
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Acute administration of methamphetamine decreases the mRNA expression of diazepam binding inhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Hashimoto A, Kawaguchi M, Bryne WD, Kobayashi H
- Journal Title
  
  Tokai J Exp Clin Med 33(1)
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition2008
- Author(s)
  Akahori K, Kosaka K, Jin XL, Arai Y, Yoshikawa M, Kobayashi H, Oka T
- Journal Title
  
  J Pharmacol Sci 106(2)
  
  Pages: 295-300
- NAID
  10024318545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Mice lacking D-amino acid oxidase activity exhibit marked reduction of methamphetamine -induced stereotypy.2008
- Author(s)
  Hashimoto A., Konno R., Yano H., Yoshikawa M., Tamaki R., Matsumoto H., Kobayashi H.
- Journal Title
  
  Eur. J. Pharmacol. 586
  
  Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] Chronic administration of methamphetamine increases the mRNA expression of diazepam binding inhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Andoh H, Kawaguchi M, Hashimoto A, Bryne WD, Kobayashi H
- Journal Title
  
  Tokai J Exp Clin Med 33(1)
  
  Pages: 46-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Long-Torm Treatmont With Morphino Increases tho D-Seine Content in the Rat Brain by Regulating the mRNA and Protein Expressions of Serine Racemase and D-Amino Acid Oxidase2008
- Author(s)
  Masanobu Yoshikawa
- Journal Title
  
  Journal of Pharmacological Sciences 107
  
  Pages: 270-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Midazolam attenuates the antinociception induced by D-serine or morphine at the supraspinal level in rats2008
- Author(s)
  Ito K, Yoshikawa M, Maeda M, Jin XL, Takahashi S, Matsuda M, Tamaki R, Kobayashi H, Suzuki T, Hashimoto A
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Chronic administration of methamphetamine increases the mRNA expression of diazepam binding inhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Andoh H, Kawaguchi M, Hashimoto A, Bryne WD, Kobayashi H.
- Journal Title
  
  Tokai J Exp Clin Med 33(1)
  
  Pages: 46-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Midazolam attenuates the antinociception induced by D-serine or morphine at the supraspinal level in rats2008
- Author(s)
  Ito K, Yoshikawa M, Maeda M, Jin XL, Takahashi S, Matsuda M, Tamaki R, Kobayashi H, Suzuki T, Hashimoto A
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  Yoshikawa M, Shinomiya T, Takayasu N, Tsukamoto H, Kawaguchi M, Kobayashi H, Oka T, Hashimoto A
- Journal Title
  
  J Pharmacol Sci 107(3)
  
  Pages: 270-276
- NAID
  10024321297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is expressed in both neurons and glial cells of rat retina2008
- Author(s)
  Takayasu N, Yoshikawa M, Watanabe M, Tsukamoto H, Suzuki T, Kobayashi H, Noda S
- Journal Title
  
  Arch Histol Cytol 71(2)
  
  Pages: 123-129
- NAID
  10025095752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Mice lacking D-amino acid oxidase activity exhibit marked reduction of methamphetamine -induced stereotypy2008
- Author(s)
  Hashimoto A, Konno R, Yano H, Yoshikawa M, Tamaki R, Matsumoto H, Kobayashi H
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase.2008
- Author(s)
  Yoshikawa M., et al.
- Journal Title
  
  J. Pharmcol. Sci. 107
  
  Pages: 270-276
- NAID
  10024321297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] Mice lacking D-amino acid oxidase activity exhibit marked reduction of methamphetamine -induced stereotypy2008
- Author(s)
  Hashimoto A, Konno R, Yano H, Yoshikawa M, Tamaki R, Matsumoto H, Kobayashi H
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is expressed in both neurons and glial cells of rat retina2008
- Author(s)
  Takayasu N, Yoshikawa M, Watanabe M, Tsukamoto H, Suzuki T, Kobayashi H, Noda S
- Journal Title
  
  Arch Histol Cytol 71(2)
  
  Pages: 123-129
- NAID
  10025095752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591843
[Journal Article] Long-Term Treatment With Morphine Increases the D-Seine Content in the Rat Brain by Regulating the mRNA and Protein Expressions of Serine Racemase and D-Amino Acid Oxidase2008
- Author(s)
  Masanobu Yoshikawa
- Journal Title
  
  Journal of Pharmacological Sciences 107
  
  Pages: 270-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Midazolam attenuates the antinociception induced by D-serine or morphine at the supraspinal level in rats2008
- Author(s)
  Ito K, Yoshikawa M, Maeda M, Jin XL, Takahashi S, Matsuda M, Tamaki R, Kobayashi H, Suzuki T, Hashimoto A
- Journal Title
  
  Eur J Pharmacol 856(1-3)
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Chronic administration of methamphetamine increases the mRNA expression of diazepam binding inhibitor in rat brain2008
- Author(s)
  Tamaki R, Yoshikawa M, Shinomiya T, Andoh H, Kawaguchi M, Hashimoto A, Bryne WD, Kobayashi H
- Journal Title
  
  Tokai J Exp Clin Med 33(1)
  
  Pages: 46-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Yoshikawa M., Takayasu N., Hashimoto A., Sato Y., Tamaki R., Tsukamoto H., Kobayashi H., Noda S.
- Journal Title
  
  Arch. Histol. Cytol. 70
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Yoshikawa M, Takayasu N, Hashimoto A, Sato Y, Tamaki R, Tsukamoto H, Kobayashi H, Noda S
- Journal Title
  
  Arch Histol Cytol 70(2)
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Activation of supraspinal NMDA receptor by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail flick test of rats2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  European Journal of Pharmacology 565
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick2007
- Author(s)
  Yoshikawa M., Ito K., Maeda M., Akahori K., Takahashi S., Jin X.L., Matsuda M., Suzuki T., Oka T., Kobayashi H., Hashimoto A.
- Journal Title
  
  Eur. J. Pharmacol. 565
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  Archives of Histology and Cytology 70
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Effects of MK-801 on the expression of serine racemase and D-amino acid oxidase mRNAs and on the D-serine levels in rat brain2007
- Author(s)
  Hashimoto A, Yoshikawa M, Andoh H, Yano H, Matsumoto H, Kawaguchi M, Oka T, Kobayashi H
- Journal Title
  
  Eur J Pharmacol 555(1)
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats2007
- Author(s)
  Yoshikawa M, Ito K, Maeda M, Akahori K, Takahashi S, Jin XL, Matsuda M, Suzuki T, Oka T, Kobayashi H, Hashimoto A
- Journal Title
  
  Eur J Pharmacol 565(1-3)
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats2007
- Author(s)
  Yoshikawa Masanobu, et. al.
- Journal Title
  
  European Journal of Pharmacology 565
  
  Pages: 89-97
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] The enhancing effects of peptidase inhibitors on antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats2007
- Author(s)
  Takahashi S, Jin XL, Kosaka K, Yoshikawa M, Kobayashi H, Oka T
- Journal Title
  
  J Pharmacol Sci 105(1)
  
  Pages: 117-121
- NAID
  10024315987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Yoshikawa, Masanobu, et. al.
- Journal Title
  
  Arch Hdtol Cytol 70(2)
  
  Pages: 127-134
- NAID
  10019551068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Effects of MK-801 on the expression of serine racemase and D-amino acid oxidase mRNAs and on the D-serine levels in rat brain.2007
- Author(s)
  Hashimoto A., Yoshikawa M., Andoh H., Yano H., Matsumoto H., Kawaguchi M., Oka T., Kobayashi H.
- Journal Title
  
  Eur. J. Pharmacol 555
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats2007
- Author(s)
  Yoshikawa, Masanobu, et. al.
- Journal Title
  
  Eur J Pharmacol 565(1-3)
  
  Pages: 89-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Yoshikawa M, Takayasu N, Hashimoto A, Sato Y, Tamaki R, Tsukamoto H, Kobayashi H, Noda S
- Journal Title
  
  Arch Histol Cytol 70(2)
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  Archives of Histology and Cytology 70
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats2007
- Author(s)
  Yoshikawa M, Ito K, Maeda M, Akahori K, Takahashi S, Jin XL, Matsuda M, Suzuki T, Oka T, Kobayashi H, Hashimoto A
- Journal Title
  
  Eur J Pharmacol 565(1-3)
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] The enhancing effects of peptidase inhibitors on antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats2007
- Author(s)
  Takahashi S, Jin XL, Kosaka K, Yoshikawa M, Kobayashi H, Oka T
- Journal Title
  
  J Pharmacol Sci 105(1)
  
  Pages: 117-121
- NAID
  10024315987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Yoshikawa Masanobu, et. al.
- Journal Title
  
  Archives of Histology and Cytology 70
  
  Pages: 127-134
- NAID
  10019551068
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Effects of MK-801 on the expression of serine racemase and D-amino acid oxidase mRNAs and on the D-serine levels in rat brain2007
- Author(s)
  Hashimoto A, Yoshikawa M, Andoh H, Yano H, Matsumoto H, Kawaguchi M, Oka T, Kobayashi H
- Journal Title
  
  Eur J Pharmacol 555(1)
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] The serine racemase mRNA is predominantly expressed in rat brain neurons2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  Archives of Histology and Cytology 70
  
  Pages: 127-134
- NAID
  10019551068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603016
[Journal Article] Activation of supraspinal NMDA receptor by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail flick test of rats2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  European Journal of Pharmacology 565
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591820
[Journal Article] Activation of suprasphinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats.2007
- Author(s)
  Masanobu Yoshikawa, et. al.
- Journal Title
  
  European Journal of Pharmacology 565
  
  Pages: 89-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590258
[Journal Article] Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons2006
- Author(s)
  Yoshikawa, Masanobu, et. al.
- Journal Title
  
  Eur J Pharmacol 548(1-3)
  
  Pages: 74-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons2006
- Author(s)
  Yoshikawa Masanobu, et. al.
- Journal Title
  
  European Journal of Pharmacology 548
  
  Pages: 74-76
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Acute treatment with morphine augments the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain2005
- Author(s)
  Yoshikawa, Masanobu, et. al.
- Journal Title
  
  Eur J Pharmacol 525(1-3)
  
  Pages: 94-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Acute treatment with morphine augments the expression of serine race mase and D-amino acid oxidase mRNAs in rat brain2005
- Author(s)
  Yoshikawa Masanobu, et. al.
- Journal Title
  
  European Journal of Pharmacology 525
  
  Pages: 94-97
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591723
[Journal Article] Effect of three peptidase inhibitors on antinociceptive potential and toxicity with intracerebroventricular administration of dynorphin A (1-17) or (1-13) in rat
- Author(s)
  Ajimi J, Yoshikawa M, Takahashi S, Miura M, Tsukamoto H, Kawaguchi M, Kobayashi H, Suzuki T
- Journal Title
  
  J. Anesthesia
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592312
[Journal Article] Activation of supraspinal NMDA receptor by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail flick test of rats
- Author(s)
  Masanobu Yoshikawa, Kenji Ito, et al. (他9名)
- Journal Title
  
  European Journal of Pharmacology (In press)
- Data Source
  KAKENHI-PROJECT-18591723
[Presentation] 慢性再発性多発性骨髄炎モデル動物における疼痛発現機序の解2023
- Author(s)
  阿部幸一郎、吉川正信
- Organizer
  第95回日本遺伝学会
- Data Source
  KAKENHI-PROJECT-21K05991
[Presentation] イミプラミンは唾液腺内ノルエピネフリン、セロトニン遊離量を増加する唾液腺マイクロダイアリシス法を用いた検討2022
- Author(s)
  白勢康介　姜卓義　渡邊真理子　松田光正　伊藤健二　鈴木武志　小林広幸　吉川正信
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09102
[Presentation] イミプラミンは唾液腺内ノルエピネフリン、セロトニン遊離量を増加する唾液腺マイクロダイアリシス法を用いた検討2022
- Author(s)
  白勢康介姜卓義渡邊真理子松田光正伊藤健二鈴木武志小林広幸吉川正信
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K09004
[Presentation] D-セリンはラット顎下腺間質液中に遊離されるアセチルコリン量を増加する2022
- Author(s)
  吉川正信大久保みぎわ川口充
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K09004
[Presentation] D-セリンはラット顎下腺間質液中に遊離されるアセチルコリン量を増加する2022
- Author(s)
  吉川正信大久保みぎわ川口充
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09053
[Presentation] イミプラミンは唾液腺内ノルエピネフリン、セロトニン遊離量を増加する唾液腺マイクロダイアリシス法を用いた検討2022
- Author(s)
  白勢康介姜卓義渡邊真理子松田光正伊藤健二鈴木武志小林広幸吉川正信
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K08955
[Presentation] 疾患モデルマウスを用いた慢性再発性多発性骨髄炎における疼痛発現機序の解析2022
- Author(s)
  阿部幸一郎，ヘルムット　フックス、マーティン　フラベデアンゲリス、吉川正信
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K05991
[Presentation] D-セリンはラット顎下腺間質液中に遊離されるアセチルコリン量を増加する2022
- Author(s)
  吉川正信　大久保みぎわ　川口充
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09102
[Presentation] D-セリンはラット顎下腺間質液中に遊離されるアセチルコリン量を増加する2022
- Author(s)
  吉川正信大久保みぎわ川口充
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K08955
[Presentation] イミプラミンは唾液腺内ノルエピネフリン、セロトニン遊離量を増加する唾液腺マイクロダイアリシス法を用いた検討2022
- Author(s)
  白勢康介姜卓義渡邊真理子松田光正伊藤健二鈴木武志小林広幸吉川正信
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09053
[Presentation] イミプラミンは唾液腺内ノルエピネフリン、セロトニン遊離量を増加する唾液腺マイクロダイアリシス法を用いた検討2022
- Author(s)
  白勢康介姜卓義渡邊真理子松田光正伊藤健二鈴木武志小林広幸吉川正信
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K08931
[Presentation] D-セリンはラット顎下腺間質液中に遊離されるアセチルコリン量を増加する2022
- Author(s)
  吉川正信大久保みぎわ川口充
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K08931
[Presentation] ラット顎下腺内副交感神経終末からのアセチルコリン遊離に対するD-セリンの作用2019
- Author(s)
  吉川正信、大久保みぎわ、川口充
- Organizer
  第64回日本唾液腺学会総会
- Data Source
  KAKENHI-PROJECT-18K09514
[Presentation] D-アミノ酸と唾液腺2013
- Author(s)
  吉川正信,大久保みぎわ,三次百合香,濱瀬健司,村山千恵子,金野柳一,川口充
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  東北大学(宮城)
- Year and Date
  2013-03-19
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] D-methionine as a protector for irradiation-induced oral mucositis or salivary glands dysfunction2013
- Author(s)
  吉川正信,村山千恵子, Ana P. Cotrium,平山亮一,古澤佳也,塚田秀雄, Bruce J Baum
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] D-アミノ酸と唾液分泌2013
- Author(s)
  吉川正信,大久保みぎわ,三次百合香,濱瀬健司,金野柳一,川口充
- Organizer
  D-アミノ酸研究会第9回学術講演会
- Place of Presentation
  関西大学(大阪)
- Year and Date
  2013-09-14
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] 放射線障害に対する防護薬としてのD体アミノ酸の可能性2013
- Author(s)
  吉川正信,村山千恵子,古澤佳也,平山亮一,鵜澤玲子,松本謙一郎
- Organizer
  第15回癌治療増感研究シンポジウム
- Place of Presentation
  猿沢荘(奈良)
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] 重粒子線照射による口腔粘膜障害および唾液腺機能障害に対するD-メチオニンの防護効果2012
- Author(s)
  吉川正信,村山千恵子,平山亮一,鵜澤玲子,古澤佳也
- Organizer
  第41回放射線による制癌シンポジウム
- Place of Presentation
  フェストーネ(沖縄)
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] Effects of three peptidase inhibitors on antinosiceptive action of Dynoephin A by intrathecal administration in rat2012
- Author(s)
  Ajimi J, Miura M, Takahashi S, Watanabe M, Yoshikawa M, Suzuki T
- Organizer
  2011年度日本薬理学会年会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] Oral mucositis resultiing from irradiation2012
- Author(s)
  吉川正信
- Organizer
  The 85th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] X線・重粒子線照射による口腔粘膜障害・唾液腺機能障害に対するD-メチオニンの防護効果2012
- Author(s)
  吉川正信,村山千恵子, Ana P. Cotrium,平山亮一,鵜澤玲子, Bruce J Baum,古澤佳也
- Organizer
  第8回D-アミノ酸研究会学術集会
- Place of Presentation
  滋賀医科大学(滋賀)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] Oral Mucositis resulting from irradiation2012
- Author(s)
  吉川正信
- Organizer
  The 85^<th> Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  京都国際会館(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] セボフルランのラット髄腔内投与による抗侵害効果の検討2011
- Author(s)
  金澤正浩、村田智彦、吉川正信、鈴木利保
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸ポートピア(神戸)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] ラット髄腔内に投与したペプチド分解酵素阻害剤によるロイシンエンケファリンの鎮痛効果の増強2011
- Author(s)
  三浦正明、渡邊真理子、高橋滋、吉川正信、鈴木利保
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸ポートピア(神戸)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] メチオニンエンケファリンの鎮痛効果に及ぼすオピオイドペプチド分解酵素阻害剤の影響2011
- Author(s)
  村田智彦、渡邊真理子、松田光正、吉川正信、高橋滋、鈴木利保
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸ポートピア(神戸)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] 放射線照射による口腔粘膜障害に対するD体メチオニンの防護効果2011
- Author(s)
  吉川正信,村山千恵子, Ana P. Cotrium, Anastatia L. Sower, James B. Mitchell, Bruce J Baum
- Organizer
  第31回日本歯科薬物療法学会
- Place of Presentation
  幕張メッセ国際会議場(千葉)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-23592312
[Presentation] Subchronic administration of ketamine decreases the mRNA expression of serine racemase in rat brain2011
- Author(s)
  Watanabe M, Yoshikawa M, Suzuki T, Takeyama K, Takahashi S
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸ポートピア(神戸)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] D-Methionine as a protector for irradiation-oral mucositis2010
- Author(s)
  Yoshikawa M, Cotrim PA, Sower AL, Mitchell JB, Baum BJ
- Organizer
  39th Annual Meetng of American Asociation of Dental Research. Washington D. C. Convention Center
- Place of Presentation
  USA, Washington D. C.
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] ケタミン長期投与によるDセリン代謝関連酵素遺伝子発現の変化2009
- Author(s)
  渡邊真理子, 吉川正信, 竹山和秀, 村田智彦, 金幸禄, 小林智美, 橋本篤司, 小林広幸, 鈴木利保
- Organizer
  第82回日本薬理学会年会
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] ケタミン長期投与によるDセリン代謝関連酵素遺伝子発現の変化2009
- Author(s)
  渡邊真理子, 吉川正信, 竹山和秀, 村田智彦, 金幸禄, 小林智美, 橋本篤司, 小林広幸, 鈴木利保
- Organizer
  第82回日本薬理学会年会
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] ケタミン長期投与によるD-セリン代謝関連酵素遺伝子発現の変化2009
- Author(s)
  渡邊真理子、吉川正信、竹山和秀、村田智彦、金幸禄、小林智美、橋本篤司、小林広幸、鈴木利保
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-21590292
[Presentation] セリンラセマーゼ遺伝子のラット眼組織における発現について2009
- Author(s)
  野田節子,高安直子,渡辺真理子,吉川正信
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] ケタミン長期投与によるDセリン代謝関連酵素遺伝子発現の変化2009
- Author(s)
  渡邊真理子,吉川正信,竹山和秀,村田智彦,金幸禄,小林智美,橋本篤司,小林広幸,鈴木利保
- Organizer
  第82回日本薬理学会年会
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] セリンラセマーゼ遺伝子のラット眼組織における発現について2009
- Author(s)
  野田節子, 高安直子, 渡辺真理子, 吉川正信
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] セリンラセマーゼ遺伝子のラット眼組織における発現について2009
- Author(s)
  野田節子, 高安直子, 渡辺真理子, 吉川正信
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] The change of upper limbs PVI in spinal block(The comparison in high spinal block and non-high spinal block)2009
- Author(s)
  K.Takeyama, M.Yoshikawa, T.Suzuki
- Organizer
  Euroanesthesia 2009
- Place of Presentation
  Milano Convention Center
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] ケタミン長期投与によるD-セリン代謝酵素遺伝子発現の変化2009
- Author(s)
  渡邊真理子、吉川正信、竹山和秀、村田智彦、金幸禄、小林智美、橋本篤司、小林広幸、鈴木利保
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590258
[Presentation] The change of upper limbs PVI in spinal block(The comparison in high spinal block and non-high spinal block)2009
- Author(s)
  Takeyama K, Yoshikawa M, Suzuki T.
- Organizer
  Euroanesthesia
- Place of Presentation
  Milano Convention Center(Italia Milano)
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21592026
[Presentation] セリンラセマーゼ遺伝子のラット脳神経細胞における発現について2008
- Author(s)
  6.野田節子,高安直子,佐藤雄一,橋本篤司,小林広幸,吉川正信
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] メタンフェタミン投与によるジアゼパムバインディングインヒビター遺伝子発現の変化2008
- Author(s)
  5.玉記雷太,吉川正信,四宮敬史,橋本篤司,川口充,小林広幸
- Organizer
  第118回日本薬理学会関東部会
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] D-セリン関連タンパク質のmRNAは唾液腺において発現する2008
- Author(s)
  吉川正信、四宮敬史、小林智美、赤堀一仁、橋本篤司、小林広幸、川口充
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590258
[Presentation] ホルマリンテストでのD-serineの鎮痛効果2008
- Author(s)
  4.松田光正,吉川正信,前田美保,伊藤健二,鈴木利保
- Organizer
  日本麻酔科学会第55回学術集会
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  Masanobu Yoshikawa
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation]2008
- Author(s)
  吉川正信, 四宮敬史, 小林智美, 赤堀一仁, 橋本篤司, 小林広幸, 川口充.
- Organizer
  第81回日本薬理学会年会
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  M.Yoshikawa, A.Hashimoto, H.Kobayashi
- Organizer
  Neuroscience 2008
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] ホルマリンテストでのD-serineの鎮痛効果2008
- Author(s)
  松田光正, 吉川正信, 前田美保, 伊藤健二, 鈴木利保
- Organizer
  日本麻酔科学会第55回学術集会
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation]2008
- Author(s)
  吉川正信,四宮敬史,小林智美,赤堀一仁,橋本篤司,小林広幸,川口充
- Organizer
  第81回日本薬理学会年会
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] セリンラセマーゼ遺伝子のラット脳神経細胞における発現につ遺伝子のラット脳神経細胞における発現について2008
- Author(s)
  野田節子, 高安直子, 佐藤雄一, 橋本篤司, 小林広幸, 吉川正信
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] ラット脳室内および髄腔内投与によるL-702,324の鎮痛効果に対する作用2008
- Author(s)
  前田美保,松田光正,鈴木利保,吉川正信,橋本篤司
- Organizer
  日本ペインクリニック学会第42回大会
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase.2008
- Author(s)
  M.Yoshikawa, A.Hashimoto, H.Kobayashi
- Organizer
  Neuroscience 2008
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  M.Yoshikawa, A.Hashimoto, H.Kobayashi
- Organizer
  Neuroscience 2008
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] メタンフェタミン投与によるジアゼパムバインディングインヒビター遺伝子発現の変化2008
- Author(s)
  玉記雷太, 吉川正信, 四宮敬史, 橋本篤司, 川口充, 小林広幸
- Organizer
  第118回日本薬理学会関東部会
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase2008
- Author(s)
  Masanobu Yoshikawa
- Organizer
  Neuroscience 2008
- Place of Presentation
  WASHINGT0N, D. C. Conference Center
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] ラット脳室内および髄腔内投与によるL-702,324の鎮痛効果に対する作用2008
- Author(s)
  前田美保, 松田光正, 鈴木利保, 吉川正信, 橋本篤司
- Organizer
  日本ペインクリニック学会第42回大会
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] セリンラセマーゼ遺伝子のラット脳神経細胞における発現について2008
- Author(s)
  野田節子, 高安直子, 佐藤雄一, 橋本篤司, 小林広幸, 吉川正信
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] ラット脳室内および髄腔内投与によるL-702, 324の鎮痛効果に対する作用2008
- Author(s)
  前田美保, 松田光正, 鈴木利保, 吉川正信, 橋本篤司
- Organizer
  日本ペインクリニック学会第42回大会
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] メタンフェタミン投与によるジアゼパムバインディングインヒビター遺伝子発現の変化2008
- Author(s)
  玉記雷太, 吉川正信, 四宮敬史, 橋本篤司, 川口充, 小林広幸
- Organizer
  第118回日本薬理学会関東部会
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation]2008
- Author(s)
  吉川正信, 四宮敬史, 小林智美, 赤堀一仁, 橋本篤司, 小林広幸, 川口充
- Organizer
  第81回日本薬理学会年会
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] ホルマリンテストでのD-serineの鎮痛効果2008
- Author(s)
  松田光正, 吉川正信, 前田美保, 伊藤健二, 鈴木利保
- Organizer
  日本麻酔科学会第55回学術集会
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信, 高安直子, 野田節子, 佐藤雄一, 小林広幸, 橋本篤司
- Organizer
  第50回神経化学会大会
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] セリンラセマーゼMrnaは主に神経細胞に発現する2007
- Author(s)
  吉川正信、高安直子、野田節子、佐藤雄一、小林広幸、橋本篤司
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590258
[Presentation] Serine racemase mRNA localizes predominantly in neuron2007
- Author(s)
  Yoshikawa, Masanobu, et. al.
- Organizer
  The 50th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信, 高安直子, 野田節子, 佐藤雄一, 小林広幸, 橋本篤司
- Organizer
  第50回神経化学会大会
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信, 他
- Organizer
  第50回神経化学会大会
- Place of Presentation
  パシヒコ横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19603016
[Presentation] セリンラセマーゼmRNAは主に神経細胞に発現する2007
- Author(s)
  吉川正信, ら
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  パシヒコ横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19590258
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信,高安直子,野田節子,佐藤雄一,小林広幸,橋本篤司
- Organizer
  第50回神経化学会大会
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-20591843
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信, 他
- Organizer
  第50回神経化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591723
[Presentation] セリンラセマーゼmRNAは主に神経細胞において発現する2007
- Author(s)
  吉川正信, 他
- Organizer
  第50回神経化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19591820
[Presentation] D-METHIONINE AS A PROTECTOR FOR IRRADIATION-INDUCED ORAL MUCOSITIS OR SALIVARY GLANDS HYPOFUNCTION
- Author(s)
  吉川正信
- Organizer
  The 2nd International Conferrence of D-Amino Acid Reserach
- Place of Presentation
  栃木県文化センター
- Year and Date
  2014-09-02 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25462932
[Presentation] D-AMINO ACID AS A PROMORTER FOR SALIVATION
- Author(s)
  吉川正信
- Organizer
  The 2nd International Conferrence of D-Amino Acid Reserach
- Place of Presentation
  栃木県文化センター
- Year and Date
  2014-09-02 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25462932

1. HASHIMOTO Atsushi (80271592)

# of Collaborated Projects: 10 results

# of Collaborated Products: 40 results
2. ITO Kenji (10317779)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
3. KOBAYASHI Hiroyuki (60195807)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
4. OKA Tetsuo (40055976)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. TAKEYAMA Kazuhide (80256148)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. KAN Takugi (60580256)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
7. Matsuda Mitsumasa (10384918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. Watanabe Mariko (60609220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 松宮輝彦 (20056203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 阿部幸一郎 (90294123)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. KOMIYAMA Tomoyoshi (60439685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GOJOBORI Takashi (50162136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IWAMA Hisakazu (20398035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAMURA Youji (90463182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANAKA Tuyoshi (70414919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KOMATSU Tomoko (20234875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. LEE Masaichi (60220795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KANAZAWA Masahiro (60276847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. AJIMI Junko (80328111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHIKAWA MASANOBU 吉川 正信

YOSHIKAWA Masanobu 吉川 正信

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内因性疼痛抑制系におけるプロホルモンSMR1の役割解明Principal Investigator

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鎮静薬と唾液分泌に関する研究Principal Investigator

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Study of the effect of serotonin in the salivary glands on salivary secretion: using salivary gland microdialysis.Principal Investigator

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YOSHIKAWA MASANOBU 吉川正信

YOSHIKAWA Masanobu 吉川正信