AKIZAWA Hiromichi 秋澤宏行

… Alternative Names

秋澤宏行アキザワヒロミチ

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Researcher Number	90311795
Other IDs
Affiliation (Current)	2022: 昭和薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2022: 昭和薬科大学, 薬学部, 教授 2008 – 2012: Health Sciences University of Hokkaido, 薬学部, 准教授 2007: Chiba University, 大学院・薬学研究院, 講師 2006: 千葉大学, 大学院薬学研究院, 講師 2002: 岡山大, 自然科学研究科, 助手 2000 – 2001: 岡山大学, 大学院・自然科学研究科, 助手
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Radiation science / 医薬分子機能学 Except Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator がん / ペプチド / 核医学 / 体内動態制御 / 癌 / 放射性医薬品 / 治療効果予測 / octreotide / アイソトープ内用療法 / 腎臓 … More / チミジンホスホリラーゼ / 5-フルオロウラシル / 腫瘍 / 核医学画像診断 / スペーサー / ^<111>In / DTPA / 腎刷子縁膜酵素 / ^<III>In / 放射免疫療法 / オージェ電子 / 細胞膜透過性ペプチド / 抗体 / アルギニン / 薬学 / 刷子縁膜 / 酵素 / 刷子縁膜酵素 / 腎臟 / イメージング / 抗がん剤 / カペシタビン / ドキシフルリジン / グリオキサラーゼⅠ / 放射性分子プローブ / 質的診断 / 悪性度診断 / グリオキサラーゼI / 核医学診断 / がん治療効果予測 / イメージング剤 / 有機カチオントランスポーター / 個別化医療 / トランスポーター / セラノスティクス / ソマトスタチン / アルブミンバインダー / 多価ペプチド / 負電荷 … More Except Principal Investigator 放射線 / 腫瘍 / アイソトープ治療 / テクネチウム-99m / 放射性ヨウ素 / 分子イメージング / 多価効果 / SPECT / 核医学診断 / 核医学 / チミジンホスホリラーゼ / 抗体 / 腎障害 / 刷子縁膜酵素 / 代謝開列性スペーサ / インジウム-111 / イットリウム-90 / インジウムーll1 / レニウム-186,188 / 代謝開烈性スペーサ / イットリム-90 / 混合配位子錯体 / 標識プローブ / 結合力 / ポジトロンCT / 血管新生 / 標識抗体 / 超高比放射能 / 体内動態 / 極微量 / 抗体フラグメント / がん治療 / 内用放射線治療 / チミジンホスホリラーゼ（TP） / ヨウ素標識IIMU / 核医学診断薬 / SPECTイメージング / 5－フルオロウラシル（5-FU) / プロドラッグ / 抗がん剤Paclitaxel / 担癌モデル動物 / 5-フルオロウラシル（5-FU） / ５－FUプロドラッグ / がんの核医学的分子イメージング / IIMU / ＰＥＴ／ＳＰＥＣＴ / 5-フルオロウラシル / ホウ素中性子捕捉療法 / インビボ蛍光イメージング / EPR効果 / 放射性医薬品 / シアニン系色素 / アルブミン / EPR effect / 放射性医薬品・造影剤 / 蛍光イメージング / 内用放射線療法 / 免疫療法 / がん微小環境 / FABP4 Less

セラノスティクスを目的とした放射性標識ソマトスタチンアナログの体内動態の最適化Principal Investigator
- Principal Investigator
  
  秋澤宏行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Showa Pharmaceutical University
個別化医療を志向したがんに選択的なチミジンホスホリラーゼイメージング技術の開発Principal Investigator
- Principal Investigator
  
  秋澤宏行
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Showa Pharmaceutical University
CAR-T療法と微小環境標的内用放射線療法の融合によるがん治療革新研究
- Principal Investigator
  
  天滿敬
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
Development of a radiolabeled probe to detect a novel target, glyoxalase I, for diagnosing characteristics of cancersPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Hiromichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Showa Pharmaceutical University
Prediction of response to anticancer therapy by thymidine phosphorylase imaging: pre-clinical proof of concept
- Principal Investigator
  
  Zhao Songji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Fukushima Medical University
Development of novel boron-containing cyanine dyes for boron neutron capture therapy
- Principal Investigator
  
  ONOE Satoru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Showa Pharmaceutical University
Usefulness of imaging tumor-specific enzyme expression by radiopharmaceuticals with thymidine phosphorylase inhibitory potency
- Principal Investigator
  
  Ohkua Kazue
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Prediction of efficacy of anticancer agents by in vivo imaging of thymidine phosphorylasePrincipal Investigator
- Principal Investigator
  
  AKIZAWA Hiromichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Showa Pharmaceutical University
Development of radioiolabeled uracil derivatives as radionuclide therapeutic agents for thymidine phosphorylase expressing tumors
- Principal Investigator
  
  OHKURA Kazue
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Enzyme-sensitive radiolabeling reagent to reduce renal radioactivity after administration of radiolabeled peptide for cancer therapyPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Hiromichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Development of a radiolabeled uracil derivative as a potential PET tracer for angiogenesis imaging.
- Principal Investigator
  
  OHKURA Kazue
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
がん集積の向上を目指す標識抗体の新規設計法
- Principal Investigator
  
  荒野泰
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
Development of a novel method for reducing renal accumulation of radiolabeled peptidesPrincipal Investigator
- Principal Investigator
  
  AKIZAWA Hiromichi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Chemical design of chelating agents suitable to radiotherapy using antibody fragments as vehicles
- Principal Investigator
  
  YASUSHI Arano
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
標的分子との高い結合力を有する多価テクネチウム標識薬剤の設計
- Principal Investigator
  
  荒野泰
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
オージェ電子による微小転移巣の放射免疫療法を目的とする薬剤の体内動態制御法の研究Principal Investigator
- Principal Investigator
  
  秋澤宏行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
診断精度の向上した腫瘍核医学画像診断用タンパク質放射性薬剤の開発Principal Investigator
- Principal Investigator
  
  秋澤宏行
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Okayama University
高精度の診断を実現するペプチドを用いた腫瘍核医学画像診断薬剤の開発Principal Investigator
- Principal Investigator
  
  秋澤宏行
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  Okayama University

[Book] Technetium-99m radiopharmaceuticals for monitoring drug resistance. In : Technetium-99m Radiopharmaceuticals : Status and Trends.2009
- Author(s)
  Akizawa H, Uehara T, Arano Y.
- Total Pages
  360
- Publisher
  Sales and promotion Section, International Atomic Energy Agency
- Data Source
  KAKENHI-PROJECT-20659186
[Book] Technetium-99m Radiopharmaceuticals for lymphoscintigraphy. In : Technetium-99m Radiopharmaceuticals : Status and Trends.2009
- Author(s)
  Uehara T, Akizawa H, Arano Y.
- Total Pages
  360
- Publisher
  Sales and promotion Section, International Atomic Energy Agency
- Data Source
  KAKENHI-PROJECT-20659186
[Journal Article] Redesign of negatively charged 111 In-DTPA-octreotide derivative to reduce renal radioactivity2017
- Author(s)
  Oshima N., Akizawa H., Kawashima H., Zhao S., Zhao Y., Nishijima K. I., Kitamura Y., Arano Y., Kuge Y. and Ohkura K.
- Journal Title
  
  Nucl Med Biol
  
  Volume: 48 Pages: 16-25
- DOI
  10.1016/j.nucmedbio.2017.01.006
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09886, KAKENHI-PROJECT-15K19810, KAKENHI-PROJECT-16K10335
[Journal Article] Relationship between biodistribution of a novel thymidine phosphorylase (TP) probe and TP expression levels in normal mice2015
- Author(s)
  Zhao Ｓ., Li H.,Nishijima K.,,Zhao Y., Akizawa H,,Shimizu Y., Ohkura K., Tamaki N., KugeY.
- Journal Title
  
  Anal.Nucl.Med
  
  Volume: 29 Pages: 582-587
- DOI
  10.1007/s12149-015-0981-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461802
[Journal Article] Raiolabeled uracil derivatives as a novel SPECT probe for thymidine phosphorylase suppresses accumulation into tumor cells by target gene knockdown2011
- Author(s)
  Li H., Zhao S., Jin Y., Nishijima K., Akizawa H., Ohkura K., Tamaki N., Kuge Y
- Journal Title
  
  Nucl. Med. Commun
  
  Volume: 32 Pages: 1211-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591826
[Journal Article] New [^<11>C] phosgene based synthesis of [^<11>C] pyrimidines for positron emission tomography2009
- Author(s)
  Seki K., Nishijima K., Sanoki K., Kuge Y., Takahashi M., Akizawa H., Tamaki N., Wiebe LI., Ohkura K.
- Journal Title
  
  Heterocycles 77
  
  Pages: 1307-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] New [11C] phosgene based synthesis of [11C]- pyrimidines for positron emission tomography2009
- Author(s)
  Seki K., Nishijima K., Sanoki K., Kuge Y., Takahashi M., Akizawa H., Tamaki N., Wiebe LI., Ohkura K.
- Journal Title
  
  Heterocycles 77
  
  Pages: 1307-1321
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] Renal uptake and metabolism of radiopharma- ceuticals derived from peptides and proteins.2008
- Author(s)
  Akizawa H, Uehara T, Arano Y.
- Journal Title
  
  Adv. Drug Deliv. Review 60
  
  Pages: 1319-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Assessment of macrocyclic triamine ligands as syntons for organometallic 99mTc radiopharmaceuticals.2008
- Author(s)
  Suzuki K, Shimmura N, Thipyapong K, Uehara T, Akizawa H, Arano Y.
- Journal Title
  
  Inorg Chem 47
  
  Pages: 2593-2600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Assessment of macrocyclic triamine ligands as syntons for organo-metallic <99m>^Tc radiopharmaceuticals2008
- Author(s)
  K. Suzuki, N. SHimmura, T. Uehara, H. Akizawa, Y. Arano
- Journal Title
  
  Inorg Chem 47
  
  Pages: 2593-2600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Renal uptake and metabolism of radiopharmaceuticals Derived from peptides and proteins2008
- Author(s)
  Akizawa H, Uehara T, Arano Y.
- Journal Title
  
  Advanced Drug Delivery Reveiws 60
  
  Pages: 1319-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659186
[Journal Article] Assessment of macrocyclic triamine ligands as syntons for organometallic ^<99m>Tc radiopharmaceuticals2008
- Author(s)
  Suzuki K, Shimmura T, Thipyapong K, Uehara T, Akizawa H, Arano Y.
- Journal Title
  
  Inorg. Chem. 47
  
  Pages: 2593-2600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Assessment of macrocyclic triamine ligands as syntons for organo-metallic ^<99m>Tc radiopharmaceuticals2008
- Author(s)
  K. Suzuki, N. SHimmura, T. Uehara, H. Akizawa, Y. Arano
- Journal Title
  
  Inorg Chem 47
  
  Pages: 2593-2600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659342
[Journal Article] Renal metabolism of radiopharmaceuticals derived from peptides and proteins2008
- Author(s)
  Akizawa H, Uehara T, Arano Y
- Journal Title
  
  Adv. Drug Deliv. Reviews 60
  
  Pages: 1319-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Effect of carboxyl-group of D-glutamic acid or γ-carboxy-D-glutamic acidas N-teminal amino acid of In-diethylenetriaminepentaacetic acid-octreotide on accumulation of radioactivity in the kidney2007
- Author(s)
  H. Akizawa, M. Saito, T. Tsuka-moto, T. Ohkura, T. Shimizu, Y. Kitamura, M. Mufune, Y. Saito, Y. Arano, H. Saji.
- Journal Title
  
  Bio.Pharm.Bull 30
  
  Pages: 2226-2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Technetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart.2007
- Author(s)
  T.Uehara, T.Uemura, S.Hirabayashi, S.Adachi, K.Odaka, H.Akizawa, Y.Magata, T.Irie, Y.Arano
- Journal Title
  
  Journal of Medicinal Chemistry 50(3)
  
  Pages: 543-249
- Data Source
  KAKENHI-PROJECT-18659342
[Journal Article] Design, synthesis and evaluation of [^<186>Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels.2007
- Author(s)
  T.Uehara, M.Koike, H.Nakata, H.Hanaoka, Y.Iida, K.Hashimoto, H.Akizawa, K.Endo, Y.Arano
- Journal Title
  
  Bioconjugate Chemistry 18(1)
  
  Pages: 190-198
- Data Source
  KAKENHI-PROJECT-18659342
[Journal Article] Assessment of ^186Re-chelate-conjegated bisphosphonate for the development of new rradiopharmaceuticals for bone.2007
- Author(s)
  T.Uehara, Z-L.Jin, K.Ogawa, H.Akizawa, K.Hashimoto, M.Nakayama, Y.Arano.
- Journal Title
  
  Nuclear Mesicine and Biology 34(1)
  
  Pages: 79-87
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Effect of carboxyl-group of D-glutamic acid or γ-carboxy-D-glutamic acid as N-terminal amino acid of 111In-diethylene- triaminepentaacetic acid-octreotide on accu- mulation of radioactivity in the kidney2007
- Author(s)
  Akizawa H, Saito M, Tsukamoto I, Ohkura T, Shimizu T, Kitamura Y, Mifune I, Saito Y, Arano Y, Saji H.
- Journal Title
  
  Chem. Pharm. Bull. 30
  
  Pages: 2226-2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Bull.Effect of carboxyl-group of D-glutamic acid or γ-carboxy-D-glutamic acid as N-teminal amino acid of ^<111>ln-diethylenetriaminepentaacetic acid-Octreotide on accumulation of radioactivity in the kidney.2007
- Author(s)
  H. Akizawa, M. Saito, T. Tsuka-moto, T. Ohkura, T. Shimizu, Y. Kitamura, M. Mufune, Y. Saito, Y. Arano, H. Saji.
- Journal Title
  
  Bio. Pharm. 30
  
  Pages: 2226-2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659342
[Journal Article] Techonetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart.2007
- Author(s)
  T.Uehara, T.Uemura, S.Hirabayashi, S.Adachi, K.Odaka, H.Akizawa, Y.Magata, T, Irie, Y.Arano.
- Journal Title
  
  Journal of Medicinal Chemistry 50(3)
  
  Pages: 543-249
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Design, synthesis and evaluation of [186Re]organorhenium-labeled antibody frag- ments with renal enzyme-cleavable linkage for low renal radioactivity levels2007
- Author(s)
  Uehara T, Koike M, Nakata H, Hanaoka H, K, Iida Y, Hashimoto K, Akizawa H, Endo K, Arano Y.
- Journal Title
  
  Bioconjugate Chem. 18
  
  Pages: 190-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Assessment of ^<186>Re-chelate-conjugated bisphosphonate for the development of new radiopharmaceuticals for bone.2007
- Author(s)
  T.Uehara, Z-L.Jin, K.Ogawa, H.Akizawa, K.Hashimoto, M.Nakayama, Y.Arano
- Journal Title
  
  Nuclear Medicine and Biology 34(1)
  
  Pages: 79-87
- Data Source
  KAKENHI-PROJECT-18659342
[Journal Article] Design, synthesis and evaluation of [^186Re]organorhenium-labeled antibody fragments with renal enzyme-cleavble linkage for low renal redioactivity levels.2007
- Author(s)
  T.Uehara, M.Koike, H.Nakata, H.Hanaoka, Y.Iida, K.Hashimoto, H.Akizawa, K.Endo, Y.Arano.
- Journal Title
  
  Bioconjugate Chemistry 18(1)
  
  Pages: 190-198
- Data Source
  KAKENHI-PROJECT-18390328
[Journal Article] Technetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart2007
- Author(s)
  Uehara T, Uemura T, Hirabayashi S, Adachi S, Odaka K, Akizawa H, Magata Y, Irie T, Arano Y.
- Journal Title
  
  J. Med. Chem. 50
  
  Pages: 543-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] トランスポーター高発現細胞を用いたチミジンホスホリラーゼ標的放射性プローブ[123I] IIMUの取り込み機構に関する検討2022
- Author(s)
  長谷川舞衣, 宿里充穗, 尾江悟, 水野雄貴, 久下裕司, 秋澤宏行
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K08105
[Presentation] トリアゾロピリミジノン骨格を有する脂肪細胞型脂肪酸結合タンパク質標的プローブの改善に関する検討2022
- Author(s)
  田口ありさ、近藤直哉、薗田珠実、尾江　悟、秋澤宏行、天滿　敬
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H03606
[Presentation] Fatty acid binding protein-4標的PETプローブの開発に向けた新規フッ化アリール結合triazolopyrimidine誘導体の合成2021
- Author(s)
  尾江　悟、田中裕之、佐藤隆浩、水野雄貴、宿里充穗、近藤直哉、天滿　敬、秋澤宏行
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19H03606
[Presentation] 腫瘍のSPECT/OI蛍光デュアルイメージングを目的とした放射性ヨウ素結合シアニン系色素の合成と基礎的評価2019
- Author(s)
  菊地正悟、尾江悟、西紗里奈、水野雄貴、宿里充穗、佐治英郎、秋澤宏行
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-16K19858
[Presentation] チミジンホスホリラーゼ標的放射性プローブ[125I]IIMUの取り込みに対する有機カチオントランスポーターの影響2018
- Author(s)
  中山賢志、宿里充穂、東川桂、尾江悟、水野雄貴、大倉一枝、久下裕司、秋澤宏行
- Organizer
  日本薬学会第１３８年会（金沢）
- Data Source
  KAKENHI-PROJECT-26461802
[Presentation] がん集積性シアニン系色素の放射性標識誘導体化に関する基礎的検討2017
- Author(s)
  紺野龍平、尾江悟、菊地正悟、布施有理、窪田奈々、秋澤宏行
- Organizer
  第61回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-16K19858
[Presentation] 放射性ヨウ素を導入したGlyoxalase I 阻害剤の合成2016
- Author(s)
  平野愛耶美、尾江悟、鈴木友久、宿里充穗、秋澤宏行
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学大学院薬学系研究科（東京都・文京区）
- Data Source
  KAKENHI-PROJECT-16K10295
[Presentation] Preclinical and translational researchs novel PET and SPECT tracers: 18F-Difa and 123I-IIMU for hypoxia and thymidine phosphorylase imaging2015
- Author(s)
  Zhao S., Nishijima K., Matsumoto H., Akizawa H., Ohkura K., Tamaki N., Kuge Y.
- Organizer
  アジアオセアニア核医学・生物学会（AOCNMB 2015）
- Place of Presentation
  韓国チェジュ
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461802
[Presentation] Preparation and evaluation of IIMU for SPECT imaging thymidine phosphorylase expression in tumors2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, Kuge Y
- Organizer
  20^<th> International Synposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] チミジンホスホリラーゼイメージング剤[^<123>I]IIMUによるCapecitabineの治療効果予測2013
- Author(s)
  小橋信弥,女池俊介,奥村侑紀,阿部務,秋澤宏行,大倉一枝,西嶋剣一,趙松吉,久下裕司,松本博樹
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] Preparation and evaluation of [123I]IIMU for SPECT imaging of thymidine phosphorylase expression in tumors.2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, and Kuge Y
- Organizer
  20th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] チミジンホスホリラーゼを標的とする新規腫瘍イメージング剤^<123>I-IIMUの開発:マウス組織におけるチミジンホスホリラーゼ発現と^<123/125>I-IIMU集積との関係2012
- Author(s)
  趙松吉,李花,西嶋剣一,秋澤宏行,大倉一枝,玉木長良,久下裕司
- Organizer
  第7回分子イメージング学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] 放射性標識核酸誘導体による腫瘍の核医学診断と内用療法2012
- Author(s)
  秋澤宏行, 趙松吉, 高橋正幸, 西嶋剣一, 関興一, 玉木長良, 下裕司, 大倉一枝
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] 放射性標識核酸誘導体による腫瘍の核医学診断と内用療法2012
- Author(s)
  秋澤宏行
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] チミジンホスホリラーゼイメージング剤[^<123>I]5-iodo-6[(2-iminoimidazoli- dinyl)methyl]uracilの開発;タンパク結合測定と画像化の検討2012
- Author(s)
  西嶋剣一, 越田早織, 趙松吉, 秋澤宏行, 大倉一枝, 松本博樹, 志賀哲, 玉木長良, 久下裕司
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] アスパラギン酸で負電荷を付与した ^In-DTPA-D-Phe^ オクトレオチド誘導体の受容体親和性および体内動態の評価2012
- Author(s)
  大島伸宏、秋澤宏行、趙松吉、趙芫、西嶋剣一、北村陽二、荒野泰、久下裕司、大倉一枝
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22791218
[Presentation] アスパラギン酸で負電荷を付与した^In-DTPA-オクトレオチドの腎集積性および in vitro における腫瘍集積性の評価2011
- Author(s)
  大島伸宏、秋澤宏行、趙松吉、趙芫、藤岳夕歌、西嶋剣一、北村陽二、荒野泰、久下裕司、大倉一枝
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-22791218
[Presentation] [^<11>C] phosgeneを用いるoxoimidazolidinylmethyluracilの合成とがんイメージングプローブへの応用2010
- Author(s)
  関興一・西嶋剣一・高橋正幸・趙松吉・向田理恵・秋澤宏行・久下裕司・玉木長良・大倉一枝
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  大阪(近畿大学)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20591457
[Presentation] [11C]phosgene を用いるoxo-imidazolidinylmethyluracil の合成とがんイメージングプローブへの応用2010
- Author(s)
  関興一・西嶋剣一・高橋正幸・趙松吉・向田理恵・秋澤宏行・久下裕司・玉木長良・大倉一枝
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20591457
[Presentation] 肝動脈塞栓療法併用アイソトープ治療を目的とする放射性ヨウ素標識環状ポリアミン誘導体の合成と基礎的検討2009
- Author(s)
  小川愛那, 富岡直子, 黒川将弘, 初芝清徳, 松島理, 秋澤宏行, 上原知也, 荒野泰
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009
- Author(s)
  宮本怜、秋澤宏行、上原知也、東佑翼、二木史郎、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20659186
[Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009
- Author(s)
  宮本怜, 秋澤宏行, 上原知也, 東祐翼, 二木史郎, 花岡宏史, 飯田靖彦, 遠藤啓吾, 荒野泰
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009
- Author(s)
  宮本怜、秋澤宏行、上原知也、東佑翼、二木史朗、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790882
[Presentation] A simple and convenient method to estimate therapeutic radiopharmaceuticals for transchatheter arterial embolization2008
- Author(s)
  Tomioka N, Akizawa H, Uehara T, Sun W-J, Kurokawa M, Matsushima S, Hatsushiba K, Hashimoto K, Arano Y.
- Organizer
  Society of Nuclear Medicine 2008 Annual Meeting
- Place of Presentation
  New Orleans
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 標的組織での集積向上を目的とするラジオアイソトープ標識抗体のアルギニンリッチペプチド修飾2008
- Author(s)
  宮本怜、秋澤宏行、上原知也、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] デンドリマーの体内動態制御に関する基礎的研究2008
- Author(s)
  上原知也, 鈴木博元, 石井大輔, 秋澤宏行, 高間雅志, 村上正裕, 荒野泰
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 標的組織での集積量の増加を目的とする抗体のアルギニン・リッチペプチド修飾2008
- Author(s)
  秋澤宏行
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18790874
[Presentation] 多価効果による標的分子への集積向上を目指した新たな99mTc標識薬剤の設計2008
- Author(s)
  宮本怜、秋澤宏行、上原知也、東佑翼、二木史郎、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
- Organizer
  第48回日本核医学会総会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20659186
[Presentation]2008
- Author(s)
  秋澤宏行, 宮本怜, 上原知也, 東祐翼, 中瀬生彦, 二木史郎, 花岡宏史, 飯田靖彦, 遠藤啓吾, 荒野泰
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 多価効果による標的分子への集積向上を目指した新たな99mTc標識薬剤の設計2008
- Author(s)
  平良優一郎、土屋将夫、内田雪絵、上原知也、秋澤宏行、荒野泰
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 多価効果による標的分子への集積向上を目指した新たな^<99m>Tc標識薬剤の設計2008
- Author(s)
  上原知也, 平良優一郎, 土屋将夫, 秋澤宏行, 荒野泰
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] Prolonged retention of antibody on target by modification with arginine-rich peptide2008
- Author(s)
  Miyamoto R, Akizawa H, Uehara T, Takayama K, Futaki S, Hanaoka H, Iida Y, Endo K, Arano Y.
- Organizer
  Society of Nuclear Medicine 2008 Annual Meeting
- Place of Presentation
  New Orleans
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] デンドリマーの体内動態制御に関する基礎的研究2008
- Author(s)
  鈴木博元、石井大輔、上原知也、秋澤宏行、高間雅志、村上正裕、荒野泰
- Organizer
  第48回日本核医学会総会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20659186
[Presentation] 肝動脈塞栓療法併用アイソトープ治療を目的とする環状ポリアミン誘導体の比較2008
- Author(s)
  秋澤宏行, 富岡直子, 黒川将弘, 上原知也, 荒野泰
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 非特異的腎集積を低減する金属RI標識抗体フラグメントの開発2007
- Author(s)
  上原知也, 平林正次, 秋澤宏行, 荒野泰
- Organizer
  第47回日本核医学会
- Place of Presentation
  仙台
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] デンドリマーの化学修飾による動態制御2007
- Author(s)
  土屋将夫, 石井大輔, 上村友恵, 内田雪絵, 上原知也, 秋澤宏行, 荒野泰
- Organizer
  日本薬学会第128年会
- Place of Presentation
  富山
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 非特異的腎集積を低減する金属RI標識抗体フラグメントの開発2007
- Author(s)
  上原知也, 平林正次, 秋澤宏行, 荒野泰
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] 標的分子への集積向上を目的とする新たな^<99m>Tc標識薬剤の設計2007
- Author(s)
  上原知也, 土屋将夫, 内田雪絵, 秋澤宏行, 荒野泰
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18659342
[Presentation] 標的分子への集積向上を目的とする新たな^<99m>Tc標識薬剤の設計2007
- Author(s)
  上原知也, 土屋将夫, 内田雪絵, 平良優一郎, 秋澤宏行, 荒野泰
- Organizer
  第47回日本核医学会
- Place of Presentation
  仙台
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-18390328
[Presentation] Preclinical evaluation of thymidine phosphorylase imaging probe, 123I-IIMU for the First-in-Human clinical trials.
- Author(s)
  Nishijima K, Zhao S, Feng F, Shimizu Y, Akizawa H, Ohkura K, Kobashi N. Abe T, Matsumoto H, Tamaki N, Kuge Y
- Organizer
  The 12th International Symposium for Future Drug Discovery and Medical Care, Perspectives of Molecular and Target Therapy
- Place of Presentation
  Sapporo
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26461802

1. OHKURA Kazue (60094827)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. KUGE Yuji (70321958)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
3. ONOE Satoru (90756107)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
4. UEHARA Tomoya (10323403)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
5. ZHAO Songji (80374239)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
6. YASUSHI Arano (90151167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
7. 宿里充穗 (20525571)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. 東川桂 (10756878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 水野雄貴 (90805194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. ENDO Keigo (10115800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. TAMAKI Nagara (30171888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 関興一 (60094835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 河嶋秀和 (70359438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 志賀哲 (80374495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北川善政 (00224957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 天滿敬 (90378787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 近藤直哉 (80756172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 藤森功 (70425453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平田雅彦 (00268301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KITAMURA Yoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. OSHIMA Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 天満敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

AKIZAWA Hiromichi 秋澤 宏行

秋澤 宏行 アキザワ ヒロミチ

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セラノスティクスを目的とした放射性標識ソマトスタチンアナログの体内動態の最適化Principal Investigator

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個別化医療を志向したがんに選択的なチミジンホスホリラーゼイメージング技術の開発Principal Investigator

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Development of a radiolabeled probe to detect a novel target, glyoxalase I, for diagnosing characteristics of cancersPrincipal Investigator

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Prediction of efficacy of anticancer agents by in vivo imaging of thymidine phosphorylasePrincipal Investigator

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Enzyme-sensitive radiolabeling reagent to reduce renal radioactivity after administration of radiolabeled peptide for cancer therapyPrincipal Investigator

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Development of a novel method for reducing renal accumulation of radiolabeled peptidesPrincipal Investigator

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AKIZAWA Hiromichi 秋澤宏行

秋澤宏行アキザワヒロミチ