Shimizu Youichi 志水陽一

… Alternative Names

SHIMIZU Youichi 志水陽一

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Researcher Number	90634212
Other IDs
External Links
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 講師 2016 – 2020: 京都大学, 医学研究科, 助教 2016 – 2017: 京都大学, 医学(系)研究科(研究院), 助教 2015: 北海道大学, 薬学研究科(研究院), 助教 2012 – 2014: 北海道大学, アイソトープ総合センター, 助教
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Basic Section 52010:General internal medicine-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 核医学 / PET / 薬学 / 放射線 / 細胞治療 / Cell Tracking / 腫瘍随伴マクロファージ / 癌 / イメージング / 2-nitroimidazole … More / 質量イメージング / 低酸素 / マクロファージ / SPECT / 動脈硬化 / 循環器 … More Except Principal Investigator 組織因子 / 放射線 / PET / 核医学 / 不安定プラーク / 核医学診断 / 分子イメージング / 乳癌 / 乳がん / 動脈硬化 / 核医学内用療法 / ソマトスタチン受容体 / DOTATOC PET / 腫瘍 / PRRT / SSTR / 膵β細胞 / GLP-1受容体 / パーキンソン病 / レビー小体病 / イメージング / αシヌクレイン / ケモカイン受容体 / pentixafor / CXCR4 / ケモカイン / ジルコニウム / ハーセプチン / 乳房専用PET / PET/MR / トラスツズマブ / HER2 / 89Zr / 5-フルオロウラシル / ＰＥＴ／ＳＰＥＣＴ / IIMU / がんの核医学的分子イメージング / ５－FUプロドラッグ / 5-フルオロウラシル（5-FU） / 担癌モデル動物 / 抗がん剤Paclitaxel / プロドラッグ / 5－フルオロウラシル（5-FU) / SPECTイメージング / 核医学診断薬 / ヨウ素標識IIMU / チミジンホスホリラーゼ（TP） / チミジンホスホリラーゼ阻害薬 / がんの悪性度評価 / F-18標識プローブ / RI内用療法 / インテグリンαvβ3 / インテグリンαvβ３ / マクロファージ / 低酸素イメージング / 人工抗体 Less

非侵襲的膵β細胞イメージングによる縦断的膵β細胞量評価法
- Principal Investigator
  
  村上隆亮
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kyoto University
Development of comprehensive PET imaging for precise diagnosis of breast cancer
- Principal Investigator
  
  中本裕士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
SR-PETによる各種腫瘍のSSTR発現評価とPRRT適応可能性の検証
- Principal Investigator
  
  河井可奈江 (三宅可奈江)
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of Cell Tracking PET imaging probes for diagnosis of cell therapyPrincipal Investigator
- Principal Investigator
  
  志水陽一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of PET imaging method of 89Zr-trastuzumab with PET/MR and dbPET
- Principal Investigator
  
  Nakamoto Yuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
Exploration of Companion Diagnosis and Personalized Medicine of Tumor Using Chemokine Receptor Imaging
- Principal Investigator
  
  石守崇好
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The Tazuke Kofukai
  Kyoto University
Development of nuclear medicine imaging method targeting alfa-synuclein aggregates for diagnosis and treatment of Lewy body disease.
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of nuclear imaging probes for detection of tumor associated macrophagesPrincipal Investigator
- Principal Investigator
  
  SHIMIZU YOICHI
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Prediction of response to anticancer therapy by thymidine phosphorylase imaging: pre-clinical proof of concept
- Principal Investigator
  
  Zhao Songji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Fukushima Medical University
Development of nuclear imaging probes for detection of tumor associated macrophagesPrincipal Investigator
- Principal Investigator
  
  SHIMIZU YOICHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
A Challenge of radio-isotope therapy for atherosclerosis: Development of a radiopharmaceutical to suppress macrophage infiltration
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
がん悪性度診断ための新規PET用チミジンホスホリラーゼＦ18イメージング剤の開発
- Principal Investigator
  
  馮飛
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Nuclear medicine imaging toward therapeutic strategy of atherosclerosis: Experimental research to establish EBM
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Deveolopment of novel SPECT imaging probe targeting extracellular matrix-related biomolecule for diagnosis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Yoichi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Specific imaging of vulnerable atherosclerotic plaque: development of a novel SPECT probe using low molecular artificial antibody
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Development of an atherosclerosis imaging probe for novel biomaker of vulnerble plaquePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Yoichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Early andspecific detection of unstable atherosclerotic pl:aqTuiesssue factor imaging using pre-targeting systems
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy2016
- Author(s)
  Shimizu Y, Hanzawa H, Zhao Y, Nishijima K, Fukura S, Sakamoto T, Zhao S, Tamaki N, Kuge Y
- Total Pages
  326
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Development of a hydroxamamide-based bifunctional chelating agent to prepare technetium-99m-labeled bivalent ligand probes2021
- Author(s)
  Shimizu Yoichi、Ando Masato、Iikuni Shimpei、Watanabe Hiroyuki、Ono Masahiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18714-18714
- DOI
  10.1038/s41598-021-98235-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08096
[Journal Article] Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging2020
- Author(s)
  Kaide S, Watanabe H, Shimizu Y, Iikuni S, Nakamoto Y, Hasegawa M, Itoh K, Ono M.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 11 Issue: 24 Pages: 4254-4261
- DOI
  10.1021/acschemneuro.0c00523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622, KAKENHI-PROJECT-20J14694
[Journal Article] Elimination of tumor hypoxia by eribulin demonstrated by 18F-FMISO hypoxia imaging in human tumor xenograft models2019
- Author(s)
  Zhao S, Yu W, Ukon N, Tan C, Nishijima K, Shimizu Y, Higashikawa K, Shiga T, Yamashita H, Tamaki N, Kuge Y.
- Journal Title
  
  EJNMMI Res
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] A novel PET probe [18F]DiFA accumulates in hypoxic region via glutathione conjugation following reductive metabolism.2019
- Author(s)
  Shimizu Y, Zhao S, Yasui H, Nishijima K, Matsumoto H, Siga T, Tamaki N, Ogawa M, Kuge Y.
- Journal Title
  
  Mol Imaging Biol
  
  Volume: 21 Issue: 1 Pages: 122-129
- DOI
  10.1007/s11307-018-1214-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] Accumulation of hypoxia imaging probe “18F-FMISO” in macrophages depends on macrophage polarization in addition to hypoxic state2019
- Author(s)
  Shimizu Yoichi、Motomura Arata、Takakura Hideo、Tamaki Nagara、Kuge Yuji、Ogawa Mikako
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: in press Issue: 5 Pages: 362-367
- DOI
  10.1007/s12149-019-01332-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19799, KAKENHI-PROJECT-19H03593
[Journal Article] In vitro uptake and metabolism of [14C]acetate in rabbit atherosclerotic arteries: biological basis for atherosclerosis imaging with [11C]acetate.2018
- Author(s)
  Yamasaki K, Yamashita A, Zhao Y, Shimizu Y, Nishii R, Kawai K, Tamaki N, Zhao S, Asada Y, Kuge Y.
- Journal Title
  
  Nucl Med Biol.
  
  Volume: 56 Pages: 21-25
- DOI
  10.1016/j.nucmedbio.2017.08.003
- NAID
  120006546743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08670, KAKENHI-PROJECT-16K10335, KAKENHI-PROJECT-16H05163, KAKENHI-PROJECT-18K19508
[Journal Article] A novel PET probe [18F]DiFA accumulates in hypoxic region via glutathione conjugation following reductive metabolism2018
- Author(s)
  Shimizu Y, Zhao S, Yasui H, Nishijima K, Matsumoto H, Siga T, Tamaki N, Ogawa M, Kuge Y.
- Journal Title
  
  Mol Imaging Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] Accumulation Mechanism of 2-Nitroimidazole-based Hypoxia Imaging Probes Revealed by Imaging Mass Spectrometry2018
- Author(s)
  Shimizu Yoichi
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 11 Pages: 1345-1352
- DOI
  10.1248/yakushi.18-00146
- NAID
  130007502889
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-11-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19799
[Journal Article] FMISO accumulation in tumor is dependent on glutathione conjugation capacity in addition to hypoxic state2017
- Author(s)
  Masaki Yukiko、Shimizu Yoichi、Yoshioka Takeshi、Nishijima Ken-ichi、Zhao Songji、Higashino Kenichi、Numata Yoshito、Tamaki Nagara、Kuge Yuji
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 31 Issue: 8 Pages: 596-604
- DOI
  10.1007/s12149-017-1189-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19799
[Journal Article] Immunoglobulin G (IgG)-Based Imaging Probe Accumulates in M1 Macrophage-Infiltrated Atherosclerotic Plaques Independent of IgG Target Molecule Expression2017
- Author(s)
  Shimizu Yoichi、Hanzawa Hiroko、Zhao Yan、Fukura Sagiri、Nishijima Ken-ichi、Sakamoto Takeshi、Zhao Songji、Tamaki Nagara、Ogawa Mikako、Kuge Yuji
- Journal Title
  
  Mol Imaging Biol
  
  Volume: 19 Issue: 4 Pages: 531-539
- DOI
  10.1007/s11307-016-1036-8
- NAID
  120006491485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Recent Advances in the Development of PET/SPECT Probes for Atherosclerosis Imaging2016
- Author(s)
  Shimizu Y, Kuge Y
- Journal Title
  
  Nuclear Medicine and Molecular Imaging
  
  Volume: 50 Issue: 4 Pages: 284-291
- DOI
  10.1007/s13139-016-0418-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-nitroimidazole-based Agent “Pimonidazole” in Hypoxia2016
- Author(s)
  Masaki Y, Shimizu Y, Yoshioka T, Fei Feng, Zhao S, Higashino K, NumataY, Kuge Y
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0161639-e0161639
- DOI
  10.1371/journal.pone.0161639
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K19799
[Journal Article] Irbesartan Attenuates Atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits: Noninvasive Imaging of Inflammation by 18F-Fluorodeoxyglucose Positron Emission Tomography.2015
- Author(s)
  Zhao Y, Fukao K, Zhao S, Watanabe A, Yamasaki K, Shimizu Y, Kubo N, Ukon N, Nakano T, Tamaki N, Kuge Y
- Journal Title
  
  Molecular Imaging
  
  Volume: 14 Issue: 5 Pages: 1-8
- DOI
  10.2310/7290.2015.00004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Optimizing of automated production of Gallium-68 radiolabeled clinical agents by cyclotron liquid target system2023
- Author(s)
  Shimizu Y, Miyake KK, Nakamoto Y
- Organizer
  EANM 2023 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07716
[Presentation] Comparison of whole-body PET/CT and dedicated breast PET with F-18 Fluoroestradiol for breast cancer detection in patients with newly diagnosed ER-positive breast cancer2023
- Author(s)
  Kanae K. Miyake, Masahiro Takada, Yoichi Shimizu, Shunsuke Yuge, Yurika Kitano, Takayoshi Ishimori, Masako Kataoka, Masahiro Kawashima, Kosuke Kawaguchi, Tae Oishi, Koji Itagaki, Yosuke Yamada, Yasuhide Takeuchi, Masakazu Toi, Yuji Nakamoto
- Organizer
  36th Annual Congress of the European Association of Nuclear Medicine 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27547
[Presentation] Optimizing the production of metal radionuclide-labeled PET imaging agents for clinical use2023
- Author(s)
  志水陽一，三宅可奈江，中本裕士
- Organizer
  第3回研究交流サロン
- Data Source
  KAKENHI-PROJECT-22K07716
[Presentation] 京大病院におけるPET用金属核種（68Ga, 64Cu, 89Zr）の臨床利用に向けた取り組み2023
- Author(s)
  志水陽一
- Organizer
  第6回Fastlabユーザーミーティング
- Invited
- Data Source
  KAKENHI-PROJECT-22K07716
[Presentation] 浸潤性小葉癌におけるF-18 FES PETの有用性2023
- Author(s)
  弓削瞬介、三宅可奈江、高田正泰、志水陽一、北野香雪、片岡正子、石守崇好、川島雅央、河口浩介、戸井雅和、中本裕士
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27547
[Presentation] 京大病院におけるPET用金属核種（68Ga, 64Cu, 89Zr）の臨床利用に向けた取り組み2023
- Author(s)
  志水陽一
- Organizer
  第6回Fastlabユーザーミーティング
- Invited
- Data Source
  KAKENHI-PROJECT-23K27547
[Presentation] Zr-89標識抗体を用いた臨床研究のための院内製造・品質試験法およびPET撮像法の標準化に関する研究2023
- Author(s)
  中本裕士、赤松剛、梶迫正明、神谷貴史、子安翔、志水陽一、仲定宏、籏野健太郎、吉本光喜、渡部直史
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27547
[Presentation] De novo ER陽性乳癌における[F-18]-FES PETの診断能：全身PET/CTと乳房PET/MRの比較2023
- Author(s)
  三宅可奈江、高田正泰、志水陽一、弓削瞬介、北野香雪、片岡正子、石守崇好、板垣孝治、川島雅央、戸井雅和、中本裕士
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27547
[Presentation] 次世代核医学診療に対応可能なサイクロトロン施設の構築2022
- Author(s)
  志水陽一
- Organizer
  PETサマーセミナー2022 in 甲府
- Invited
- Data Source
  KAKENHI-PROJECT-22K07716
[Presentation] Optimizing of automated synthesis of 68Ga-DOTATOC with Ga-68 produced by cyclotron liquid target system for clinical use2022
- Author(s)
  Shimizu Y, Kobayashi K, Kumano M, Okamura A, Saga T, Nakamoto Y.
- Organizer
  13th Congress of the World Federation of Nuclear Medicine and Biology
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] [18F]F-AraGの臨床利用に向けた多目的合成装置による製造法の検討2022
- Author(s)
  志水陽一，野橋智美，中本裕士
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] 次世代核医学診療に対応可能なサイクロトロン施設の構築2022
- Author(s)
  志水陽一
- Organizer
  PETサマーセミナー2022 in 甲府
- Invited
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] αシヌクレインイメージングプローブの開発を目的とした新規18F標識スチリルキノリン/キノキサリン誘導体の合成と評価2021
- Author(s)
  中川航平, 渡邊裕之, 貝出翔, 飯國慎平, 志水陽一, 小野正博
- Organizer
  第4回日本核医学会分科会放射性薬品科学研究会/第19回放射性医薬品・画像診断薬研究会（仙台)
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] Ga-68標識薬剤の安定供給に向けたサイクロトロン liquid target system によるGa-68製造法の検討2021
- Author(s)
  5.志水陽一，小林敬三，熊野充繁，岡村明彦，石守崇好，佐賀恒夫，中本裕士
- Organizer
  第3 回日本核医学会近畿支部会
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] サイクロトロンliquid target systemにて製造するGa-68を用いた68Ga-DOTATOC自動合成法の検討2021
- Author(s)
  1.志水陽一，小林敬三，熊野充繁，岡村明彦，石守崇好，佐賀恒夫，中本裕士
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] カルコン類縁体を基盤としたαシヌクレイン標的PETイメージングプローブの開発2021
- Author(s)
  貝出翔, 渡邊裕之, 飯國慎平, 志水陽一, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  第61回日本核医学会学術総会（名古屋）
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] 99mTc標識2価リガンドを容易に調製可能とするHydroxamamide母核二官能性キレート剤の開発2020
- Author(s)
  安藤正登，志水陽一，飯國慎平，渡邊裕之，小野正博
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08096
[Presentation] FMISO-PET imaging may be affected by inhibitors of multidrug-resistant protein 1 independent of the hypoxic state2018
- Author(s)
  Shimizu Y, Nakai Y, Watanabe H, Ono M, Saji H, Kuge Y, Nakamoto Y, Saga T, Togashi K
- Organizer
  The 65nd Society of Nuclear Medicine and Molecular Imaging 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] Investigation of the influence of intratumoral glutathione status on the distribution of a hypoxic probe [18F]FMISO.2018
- Author(s)
  Yasui H, Higashikawa K, Shimizu Y, Shibata Y, Zhao S, Matsumoto H, Shiga T, Tamaki N, Kuge Y.
- Organizer
  WFNMB 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] 質量イメージングによる低酸素領域集積性ニトロイミダゾール薬剤の集積機序の解明　―薬物療法時における[18F]FMISOを用いた低酸素PET診断への影響評価―2018
- Author(s)
  志水陽一
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] 質量イメージングによる低酸素領域集積性ニトロイミダゾール薬剤の集積機序の解明―薬物療法が低酸素PET診断に与える影響評価―2017
- Author(s)
  志水陽一，久下裕司，佐治英郎
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] イメージング質量分析によるPET診断用低酸素イメージング剤“FMISO”の腫瘍内集積機序の解明2017
- Author(s)
  志水陽一，久下裕司
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] マクロファージの極性化が18F-FMISOと125I-BMIPPの集積に及ぼす影響2017
- Author(s)
  1.本村新，志水陽一，高倉栄男，安井博宣，東川桂，玉木長良，久下裕司，小川美香子
- Organizer
  第1回放射性薬品科学研究会(京都市)
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Effect of eribulin on remodeling of tumor vasculature confirmed by FMISO PET imaging-Small-animal PET study in human breast cancer cell xenograft-2017
- Author(s)
  Zhao S, Yu W, Ukon N, Nishijima K, Shimizu Y, Higashikawa K, Yamashita H, Tamaki N, Kuge Y.
- Organizer
  The 64th Society of Nuclear Medicine Annual Meeting in Denver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] Accumulation mechanism of novel PET imaging probe “[18F]DiFA” in hypoxic cells revealed by imaging mass spectrometry.2017
- Author(s)
  Shimizu Y, Zhao S, Kishi R, Yasui H, Nishijima K, Matsumoto H, Tamaki N, Ogawa M, Kuge Y.
- Organizer
  The 64th Society of Nuclear Medicine Annual Meeting in Denver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] マクロファージの極性化18F-FMISOの細胞内集積に与える影響2016
- Author(s)
  本村新，志水陽一，高倉栄男，玉木長良，久下裕司，小川美香子
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] 低酸素イメージング剤“FMISO”の腫瘍集積におけるグルタチオン関連因子の影響2016
- Author(s)
  志水陽一，正木悠紀子，吉岡健，東野賢一，沼田義人，西嶋剣一，趙　松吉，玉木長良，小川美香子，久下裕司
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] Does FMISO-PET really visualize only hypoxic states?; accumulation mechanism assessment of FMISO in hypoxic cells in combination with mass spectrometry2016
- Author(s)
  Shimizu Y, Masaki Y, Yoshioka T, Higashino K, Numata Y, Nishijima K, Zhao S, Tamaki N. Ogawa M. Kuge Y
- Organizer
  The 63nd Society of Nuclear Medicine and Molecular Imaging 2016
- Place of Presentation
  San Diego　（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] イメージング質量分析（IMS）による低酸素診断剤“Pimonidazole”の腫瘍内集積機序の解明2016
- Author(s)
  志水陽一，正木悠紀子，吉岡健，東野賢一，沼田義人，趙　松吉，小川美香子，久下裕司
- Organizer
  第11回日本分子イメージング学会総会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] イメージング質量分析法によるPET診断用低酸素イメージング剤の腫瘍内集積メカニズムの解明2016
- Author(s)
  志水陽一
- Organizer
  第32回緑陰セミナー
- Place of Presentation
  旅亭「雪の屋」（北海道・旭川市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K19799
[Presentation] 動脈硬化病変における放射性標識化免疫グロブリンG集積機序の探索2015
- Author(s)
  .志水陽一、半澤宏子、趙芫、趙松吉、福良沙霧、西嶋剣一、坂本健、玉木長良、小川美香子、久下裕司
- Organizer
  第10回日本分子イメージング学会総会・学術総会
- Place of Presentation
  神戸サンボーホール（兵庫県、神戸市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26860961
[Presentation] Accumulation mechanism of non-targeted immunoglobulin G in atherosclerotic legions2015
- Author(s)
  Yoichi Shimizu, Hiroko Hanzawa, Yan Zhao, Songji Zhao, Sagiri Fukura, Ken-ichi Nishijima, Takeshi Sakamoto, Nagara Tamaki, and Yuji Kuge
- Organizer
  Annual Meeting of Society of Nuclear Medicine and Molecular Imaging
- Place of Presentation
  Baltimore Convention Center (Baltimore, Maryland)
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] 動脈硬化病変における放射性標識化免疫グロブリンG集積機序の探索2015
- Author(s)
  志水陽一、半澤宏子、趙芫、趙松吉、福良沙霧、西嶋剣一、坂本健、玉木長良、小川美香子、久下裕司
- Organizer
  第10回日本分子イメージング学会総会・学術総会、
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] , Radiolabeled immunoglobulin G visualizes active inflammation in atherosclerosis,2015
- Author(s)
  Sagiri Fukura, Yoichi Shimizu, Hiroko Hanzawa, Ken-ichi Nishijima, Takeshi Sakamoto, Songji Zhao, Mikako Ogawa, Yuji Kuge
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  放射線医学総合研究所(千葉県、千葉市）
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860961
[Presentation] Radiolabeled immunoglobulin G visualizes active inflammation in atherosclerosis2015
- Author(s)
  Sagiri Fukura, Yoichi Shimizu, Hiroko Hanzawa, Ken-ichi Nishijima, Takeshi Sakamoto, Songji Zhao, Mikako Ogawa, Yuji Kuge
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  National Institute of Radiological Sciences (Chiba, Japan)
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Accumulation mechanism of non-targeted immunoglobulin G in atherosclerotic legions2015
- Author(s)
  Yoichi Shimizu, Hiroko Hanzawa, Yan Zhao, Songji Zhao, Sagiri Fukura, Ken-ichi Nishijima, Takeshi Sakamoto, Nagara Tamaki, and Yuji Kuge
- Organizer
  Society of Nuclear Medicine and Molecular Imaging 2015
- Place of Presentation
  Baltimore（アメリカ）
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860961
[Presentation] 動脈硬化病変の進行における脂肪酸結合タンパク質(FABP4、FABP5)の発現変動に関する組織学的・生化学的検討2014
- Author(s)
  志水陽一, 他6名
- Organizer
  第134回日本薬学会
- Place of Presentation
  熊本市総合体育館(熊本県)
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-24890003
[Presentation] 動脈硬化病変の進行における脂肪酸結合蛋白質（FABP4、FABP5）の発現変動に関する組織学的・生化学的検討2014
- Author(s)
  志水陽一、半澤宏子、趙芫、趙松吉、坂本健、玉木長良、久下裕司
- Organizer
  第134回日本薬学会
- Place of Presentation
  熊本市総合体育館(熊本市）
- Data Source
  KAKENHI-PROJECT-24890003
[Presentation] 動脈硬化病変への免疫グロブリンG 集積機序の探索：動脈硬化診断用薬剤開発への応用に関する基礎的検討
- Author(s)
  志水陽一、半澤宏子、趙芫、福良沙霧、西嶋剣一、坂本健、趙松吉、玉木長良、久下裕司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県・神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860961
[Presentation] 多目的自動合成装置を用いたクリック反応による18F-標識ペプチドの合成：5-[18F]fluoro-1-pentyneの合成検討
- Author(s)
  大曲茂生, 小松由紀子,西嶋剣一, 志水陽一, 馮飛, 玉木長良, 久下裕司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県・神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293268

1. KUGE Yuji (70321958)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. NISHIJIMA Ken-ichi (60364254)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. Nakamoto Yuji (20360844)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. 河井可奈江 (60812641)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. ZHAO Songji (80374239)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. KAWAI Keiichi (30204663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YAMASHITA Atsushi (90372797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. 東川桂 (10756878)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. 片岡正子 (10611577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. 大倉一枝 (60094827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 石守崇好 (70742211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. Ono Masahiro (80336180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 浅田祐士郎 (70202588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鐙谷武雄 (80270726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 七戸秀夫 (80374479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 玉木長良 (30171888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
17. 馮飛 (60374196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 志賀哲 (80374495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 北川善政 (00224957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 秋澤宏行 (90311795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松本純明 (80760769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 子安翔 (80781913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 渡邊裕之 (40710786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 飯國慎平 (70837731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. 村上隆亮 (50904017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 藤本裕之 (50437274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 高田正泰 (50452363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 戸井雅和 (10207516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shimizu Youichi 志水 陽一

SHIMIZU Youichi 志水 陽一

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Development of Cell Tracking PET imaging probes for diagnosis of cell therapyPrincipal Investigator

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Development of nuclear imaging probes for detection of tumor associated macrophagesPrincipal Investigator

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Development of nuclear imaging probes for detection of tumor associated macrophagesPrincipal Investigator

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Deveolopment of novel SPECT imaging probe targeting extracellular matrix-related biomolecule for diagnosis of atherosclerosisPrincipal Investigator

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Shimizu Youichi 志水陽一

SHIMIZU Youichi 志水陽一