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MAEGAWA Hiroshi  前川 聡

… Alternative Names

前川 聡  マエカワ ヒロシ

Less
Researcher Number 00209363
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4611-8149
Affiliation (Current) 2025: 滋賀医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2022 – 2024: 滋賀医科大学, 医学部, 非常勤講師
2014 – 2021: 滋賀医科大学, 医学部, 教授
2009 – 2011: Shiga University of Medical Science, 医学部, 教授
2007 – 2008: Shiga University of Medical Science, Undergraduate School of Medicine, Associate Professor
2007: 滋賀医科大学, 医学部, 講師 … More
2005 – 2006: 滋賀医科大学, 医学部, 助教授
2005: 滋賀医科大学, 医学部滋賀医科大学・医学部, 助教授
2003 – 2004: MAEGAWA,Hiroshi, 医学部, 講師
1996 – 2002: 滋賀医科大学, 医学部, 助手
1993 – 1994: 滋賀医科大学, 医学部, 助手
1991: 滋賀医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / 内分泌・代謝学 / Biological Sciences
Except Principal Investigator
Metabolomics / 内分泌・代謝学 / Biological Sciences / Epidemiology and preventive medicine / Hygiene and public health / Metabolomics / Public health/Health science
Keywords
Principal Investigator
肥満 / PP2A / SHP-2 / チロシンホスファターゼ / SREBP-1 / PTP1B / インスリン抵抗性 / 糖尿病 / TFAP2B / CAAX signal … More / Protein phosphatase / プロテインホスファターゼ / Crk-associated substrate / トランスジェニックマウス / ケトン体 / IL-6 / 内臓脂肪組織 / 皮下脂肪組織 / レプチン / アディポネクチン / 脂肪組織 / メタボリックシンドローム / 脂質代謝 / 糖代謝 / 絶食 / 老化 / インスリン / 細胞内栄養シグナル / シグナル / 糖鎖修飾 / タンパク翻訳後修飾 / 糖尿病合併症 / Endoplasmic reticulum / SREBP-1c / Protein Tyrosine Phosphatase1B / インスリン分解 / インスリンクリアランス / 高インスリン血症 / Endoplasmic Reticulum / insulin resistance / Protein-tyrosine phosphatase / Insulin Resistance / Transgenic Mice / Protein-Tyrosine Phosphatase / Insulin resistance / Trasgenic mice / Janus kinase 2 / PTPase / SHPTP2 / Janus kinase 2 (JAK2) / Janus kinase 2(JAK2) / SHP2 / ケトン産生 / 飢餓 / 脳・神経 / 内科 / オートファジー / 腎臓 / 糖尿病性腎症 / TNFα / Adiponectin / MCP-1 / PKCμ / AP-2β / 遺伝子改変マウス / アディポサイトカイン / AP2B / 転写因子 / アディポサトカイン / Akt / PI3キナーゼ / 脂肪分化 / Small T antigen / PP2C / Glucose transporter 4 / Tumor Necrosis Factor α / adiponectin / Grb2 associated binder-1 / atypical Protein Kinase C / Phospholipase C / Src homology 2 / SH-PTP2 / PTP1C / Insulin Receptor Substrate 1 / インスリン受容体 … More
Except Principal Investigator
インスリン抵抗性 / 糖尿病 / SREBP-1c / RBMX / AP-1 / fibronectin / Ac-SDKP / Smad / TGF-β / ICAM-1 / 一般住民 / 疫学 / 動脈硬化 / 糖尿病性腎症 / 糖尿病合併症 / コホート研究 / 地域住民 / 糖代謝 / 地域一般住民 / 筋肉 / 異所性脂肪 / 予防 / 脳萎縮 / 一般女性 / 女性 / 認知症 / 遺伝子 / 1型糖尿病 / 遺伝因子 / 1型糖尿病 / free fatty acid / phosphatase / insulin resistance / diabetes mellitus / フォスファターゼ / ホスファターゼ / 遊離脂肪酸 / ボスファターゼ / Nutrients / Fructose / 果糖反応性遺伝子 / 代謝症候群 / 遺伝子発現調節 / 肝細胞 / 転写調節 / 栄養素 / 果糖 / SREBP-lc / pioglitazone / mesangial cells / MAPKs / 細胞外基質 / ピオグリタゾン / メサンギウム細胞 / Glutathione redox cycle / Oxidative LDL / Oxidative stress / Endothelial cells / Hyperglycemia / Aging / Diabetes mellitus / 動脈硬化症 / ラジカルスカベンジャー / ペントース燐酸経路 / 活性酸素 / 遺伝子発現 / 糖尿病性血管障害 / グルタチオンレドックスサイクスル / 酸化LDL / 酸化ストレス / 血管内皮細胞 / 高血糖 / 老化 / Tyrosine Kinase / Point Mutation / Syndrome of Extreme Insulin Resistance / Insulin Receptor / プロモ-タ- / インスリン受容体遺子 / インスリン受容体異常症 / 点宅燃変異 / インスリンレセプター insulin receptor / チロシン・キナーゼ / インスリン・レセプター異常症 / チロシンキナーゼ / 点突然変異 / インスリンレセプター異常症 / insulin receptor / 一般地域住民 / 国際共同研究 / 公衆衛生学 / PKC beta / 白血球DNA / 家系図 / 遺伝子多型 / 候補遺伝子 Less
  • Research Projects

    (22 results)
  • Research Products

    (128 results)
  • Co-Researchers

    (57 People)
  •  Role of Ketone bodies in glucose and lipid metabolismPrincipal Investigator

    • Principal Investigator
      前川 聡
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Shiga University of Medical Science
  •  Role of protein O-GlcNAcylation in physiology and diabetesPrincipal Investigator

    • Principal Investigator
      Maegawa Hiroshi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Shiga University of Medical Science
  •  Subclinical atherosclerosis and brain atrophy in the general Japanese women

    • Principal Investigator
      Miura Katsuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene and public health
    • Research Institution
      Shiga University of Medical Science
  •  Comprehensive analysis of autophagy in the pathogenesis of diabetes and its complicationsPrincipal Investigator

    • Principal Investigator
      Maegawa Hiroshi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Identification and characterization of susceptible genes to type 1 diabetes using in the clustered family

    • Principal Investigator
      KAWABATA Yumiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kindai University
  •  The impacts of ectopic fats in muscle, liver, and abdominal tissues on the metabolism related to glucose and insulin

    • Principal Investigator
      Fujiyoshi Akira
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Shiga University of Medical Science
  •  A study on determinants of subclinical atherosclerosis

    • Principal Investigator
      UESHIMA Hirotsugu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Public health/Health science
    • Research Institution
      Shiga University of Medical Science
  •  Role of TFAP2B as environment response gene on Metabolic SyndromePrincipal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Regulation of Adipokine Expression on Metabolic SyndromePrincipal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the postprandial state ofrata

    • Principal Investigator
      KASHIWAGI Atsunori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  The Pathophysiological Role of Protein Phosphatase 2A (PP2A) in metabolic Syndrome

    • Principal Investigator
      UGI Satoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  脂肪細胞におけるインスリン感受性獲得の分子機構と肥大化誘導分子の同定Principal Investigator

    • Principal Investigator
      前川 聡
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shiga University of Medical Science
  •  Role of Protein-tyrosine phosphatase on pathogenesis of Metabolic syndromePrincipal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Organ specificity of insulin resistance induced by Protein-tyrosine phosphatasePrincipal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  糖尿病合併症家系図の構築と糖尿病合併症候補遺伝子に検索

    • Principal Investigator
      KASHIWAGI Atsunori
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Shiga University of Medical Science
  •  糖尿病合併症家系図の構築と糖尿病合併症候補遺伝子の探索

    • Principal Investigator
      KIKKAWA Ryuichi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Shiga University of Medical Science
  •  Development of the treatment of diabetic nephropathy by targeting the TGF-β signaling

    • Principal Investigator
      KIKKAWA Ryuichi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University of Medical Science
  •  Investigation For Molecular Mechanism Of Insulin Resistance In Transgenic Mice Expressing A Mutant Shp2Principal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shiga University Of Medical Science
  •  Roles of stimulatory and inhibitory protein-tyrosine phosphatase in pathogenesis of insulin resistancePrincipal Investigator

    • Principal Investigator
      MAEGAWA Hiroshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Shiga University of Medical Science
  •  インスリンシグナル伝達におけるチロシン蛋白脱燐酸化酵素の意義Principal Investigator

    • Principal Investigator
      前川 聡
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Shiga University of Medical Science
  •  Hyperglycemia and atherosclerosis : Radical scavenger dysfunction and abnormal gene expression in endothelial cells

    • Principal Investigator
      KASHIWAGI Atsunori
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      SHIGA UNIVERSITY OF MEDICAL SCIENCE
  •  Syndrome of extreme insulin resistance due to decreased promoter activity of 5'-flanking region of insulin receptor gene.

    • Principal Investigator
      KOBAYASHI Msashi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      TOYAMA MEDICAL AND PHARMACERTICAL UNIVERSITY
      Shiga University of Medical Science

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Other

  • [Journal Article] Ketone bodies: A double‐edged sword for mammalian life span2023

    • Author(s)
      Tomita Issei、Tsuruta Hiroaki、Yasuda‐Yamahara Mako、Yamahara Kosuke、Kuwagata Shogo、Tanaka‐Sasaki Yuki、Chin‐Kanasaki Masami、Fujita Yukihiro、Nishi Eiichiro、Katagiri Hideki、Maegawa Hiroshi、Kume Shinji
    • Journal Title

      Aging Cell

      Volume: in press Issue: 6 Pages: 1-5

    • DOI

      10.1111/acel.13833

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-23K21619, KAKENHI-PROJECT-23K24387, KAKENHI-PROJECT-22K19428
  • [Journal Article] Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine2022

    • Author(s)
      Nishimura Kimihiro、Fujita Yukihiro、Ida Shogo、Yanagimachi Tsuyoshi、Ohashi Natsuko、Nishi Kiyoto、Nishida Atsushi、Iwasaki Yasumasa、Morino Katsutaro、Ugi Satoshi、Nishi Eiichiro、Andoh Akira、Maegawa Hiroshi
    • Journal Title

      Molecular Metabolism

      Volume: 59 Pages: 101458-101458

    • DOI

      10.1016/j.molmet.2022.101458

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08998, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-18H02862, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-21K20867
  • [Journal Article] O-GlcNAc修飾と疾患2021

    • Author(s)
      森野 勝太郎, 大橋 夏子, 井田 昌吾, 前川 聡
    • Journal Title

      循環器内科

      Volume: 64 Pages: 111-113

    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Journal Article] Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes2019

    • Author(s)
      Sugahara S, Kume S, Chin-Kanasaki M, Tomita I, Yasuda-Yamahara M, Yamahara K, Takeda N, Osawa N, Yanagita M, Araki SI, Maegawa H.
    • Journal Title

      Journal of the American Society of Nephrology

      Volume: In press Issue: 6 Pages: 962-978

    • DOI

      10.1681/asn.2018090950

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09612, KAKENHI-PROJECT-19K08724, KAKENHI-PROJECT-18K15998, KAKENHI-PROJECT-18H02862
  • [Journal Article] Lack of O-GlcNAcylation enhances exercise-dependent glucose utilization potentially through AMP-activated protein kinase activation in skeletal muscle2018

    • Author(s)
      Murata Koichiro、Morino Katsutaro、Ida Shogo、Ohashi Natsuko、Lemecha Mengistu、Park Shi-Young、Ishikado Atsushi、Kume Shinji、Choi Cheol Soo、Sekine Osamu、Ugi Satoshi、Maegawa Hiroshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 495 Issue: 2 Pages: 2098-2104

    • DOI

      10.1016/j.bbrc.2017.12.081

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09383, KAKENHI-PROJECT-18H02862, KAKENHI-PROJECT-16K09744
  • [Journal Article] Emerging role of mammalian autophagy in ketogenesis to overcome starvation.2016

    • Author(s)
      Takagi A, Kume S, Maegawa H, Uzu T.
    • Journal Title

      Autophagy. 2016;12(4):709-10.

      Volume: 12 Issue: 4 Pages: 709-10

    • DOI

      10.1080/15548627.2016.1151597

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293217, KAKENHI-PROJECT-25713033
  • [Journal Article] Lipoprotein-associated phospholipase A2 related to the risk of subclinical atherosclerosis independent of small low density lipoprotein particles in a general Japanese population.2016

    • Author(s)
      Ueshima H, Kadowaki T, Fujiyoshi A, Miura K, Ohkubo T, Kadota A, Kadowaki S, Nakamura Y, Miyagawa N, Okamura T, Kita Y, Takashima N, Kashiwagi A, Maegawa H, Horie M, Yamamoto T, et ai.
    • Journal Title

      Athelosclerosis

      Volume: 246 Pages: 141-147

    • DOI

      10.1016/j.atherosclerosis.2015.12.027

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461068, KAKENHI-PROJECT-15K19224, KAKENHI-PROJECT-24790616, KAKENHI-PROJECT-26293140, KAKENHI-PROJECT-25253046, KAKENHI-PROJECT-15H04818
  • [Journal Article] Impaired podocyte autophagy exacerbates proteinuria in diabetic nephropathy.2016

    • Author(s)
      Tagawa A, Yasuda M, Kume S, Ymahara K, Nakazawa J, Chin-Kanasaki M, Araki H, Araki SI, Koya D, Asanuma K, Kim EH, Haneda M, Kajiwara N, Hayashi K, Ohashi H, Ugi S, Maegawa H, Uzu T
    • Journal Title

      Diabetes.

      Volume: - Issue: 3 Pages: 755-767

    • DOI

      10.2337/db15-0473

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670431, KAKENHI-PROJECT-15K19511, KAKENHI-PROJECT-26893116, KAKENHI-PROJECT-26293217, KAKENHI-PROJECT-25713033
  • [Journal Article] Mammalian autophagy is essential for hepatic and renal ketogenesis during starvation.2016

    • Author(s)
      Takagi A, Kume S, Kondo M, Nakazawa J, Chin-Kanasaki M, Araki H, Araki S, Koya D, Haneda M, Chano T, Matsusaka T, Nagao K, Adachi Y, Chan L, Maegawa H, Uzu T.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 18944-18944

    • DOI

      10.1038/srep18944

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460648, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-26293217, KAKENHI-PROJECT-25713033, KAKENHI-PROJECT-25293130
  • [Journal Article] Emerging role of podocyte autophagy in the progression of diabetic nephropathy.2015

    • Author(s)
      Yasuda-Yamahara M, Kume S, Tagawa A, Maegawa H, Uzu T.
    • Journal Title

      Autophagy

      Volume: 11 Issue: 12 Pages: 2385-2386

    • DOI

      10.1080/15548627.2015.1115173

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19511, KAKENHI-PROJECT-26293217, KAKENHI-PROJECT-25713033
  • [Journal Article] Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.2015

    • Author(s)
      Yasuda-Yamahara M, Kume S, Yamahara K, Nakazawa J, Chin-Kanasaki M, Araki H, Araki S, Koya D, Haneda M, Ugi S, Maegawa H, Uzu T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 18 Issue: 2 Pages: 249-255

    • DOI

      10.1016/j.bbrc.2015.08.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19511, KAKENHI-PROJECT-26893116, KAKENHI-PROJECT-26293217
  • [Journal Article] High-density lipoprotein particle concentration and subclinical atherosclerosis of the carotid arteries in Japanese men.2015

    • Author(s)
      Zaid M, Fujiyoshi A, Miura K, Abbott RD, Okamura T, Takashima N, Torii S, Saito Y, Hisamatsu T, Miyagawa N, Ohkubo T, Kadota A, Sekikawa A, Maegawa H, Nakamura Y, Mitsunami K, Ueshima H.
    • Journal Title

      Atherosclerosis

      Volume: 239 Pages: 444-450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293140
  • [Journal Article] 肥満と腎臓病 新規治療標的の開発を目指して2014

    • Author(s)
      久米真司 前川聡
    • Journal Title

      肥満研究

      Volume: 20 Pages: 160-167

    • NAID

      40020321227

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Journal Article] Autophagy regulates inflammation in adipocytes2012

    • Author(s)
      YoshizakiT, Kusunoki C, Kondo M, Yasuda M, Kume S, Morino K, Sekine O, Ugi S, Uzu T, Nishio Y, Kashiwagi A, Maegawa H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Pages: 352-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Autophagy regulates inflammation in adipocytes2012

    • Author(s)
      Yoshizaki T, Maegawa H., et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Issue: 1 Pages: 352-357

    • DOI

      10.1016/j.bbrc.2011.11.114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129, KAKENHI-PROJECT-21591162, KAKENHI-PROJECT-24591322, KAKENHI-PROJECT-24591350
  • [Journal Article] Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes2012

    • Author(s)
      Morino K, Maegawa H, et al
    • Journal Title

      Diabetes

      Volume: 61 Issue: 4 Pages: 877-87

    • DOI

      10.2337/db11-1391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin Resistant Offspring of Parents with Type 2 Diabetes2012

    • Author(s)
      Morino K, Petersen KF, Sono S, Choi CS, Varman T. Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A, Ira J. Goldberg IR, Wang H, , Robert H. Eckel RH, Maegawa H, and Shulman GI
    • Journal Title

      Diabetes

      Volume: 61 Pages: 877-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Postprandial activation of protein kinase Cμregulates the expression of adipocytokines via the transcription factor AP-2β2011

    • Author(s)
      Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H.
    • Journal Title

      Int J Mol Med

      Volume: 28 Pages: 95-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Postprandial activation of protein kinase CM regulates the expression of adipocytokines via the transcription factor AP-2β.2011

    • Author(s)
      Kondo M, Maegawa, et al
    • Journal Title

      Int J Mol Med.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Association between serum soluble TNFα receptors and renal dysfunction in type 2 diabetic patients without proteinuria.2011

    • Author(s)
      Miyazawa I, Maegawa H., et al.
    • Journal Title

      Diab Research Clin Pract

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Postprandial activation of protein kinase Cμ regulates the expression of adipocytokines via the transcription factor AP-2ss2011

    • Author(s)
      Kondo M, Maegawa H, et al
    • Journal Title

      Int J Mol Med.

      Volume: 28 Pages: 95-100

    • DOI

      10.3892/ijmm.2011.651

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129, KAKENHI-PROJECT-21591162
  • [Journal Article] Transcription factor AP-2βinhibits expression and secretion of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes2010

    • Author(s)
      Fuke T, Yoshizaki T, Kondo M, Morino K, Obata T, Ugi S, Nishio Y, Maeda S, Kashiwagi A, Maegawa H.
    • Journal Title

      Int J of Obesity

      Volume: 34 Pages: 670-678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues2010

    • Author(s)
      Ugi S, Nishio Y, Yamamoto H, Ikeda K, 5 KobayashiM, Tsukada S Kondo S, Morino K, Obata T, Yoshizaki T, Uzu T, Naitoh H, Tani T, Maeda S, Kashiwagi A, and Maegawa H.
    • Journal Title

      Obesity

      Volume: 18 Pages: 1277-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] ERA JUMP Study group.: Circulating levels of 8 cytokines and marine n-3 fatty acids and indices of obesity in Japanese, white, and Japanese American middle-aged men2010

    • Author(s)
      Sekikawa A, Kadowaki T, Maegawa H, Kadota A, Ueshima H, 他10名14番目
    • Journal Title

      J Interferon Cytokine Res.

      Volume: 30(7) Pages: 541-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249043
  • [Journal Article] Possible role of transcriptional factor TFAP2B in regulation of adipokine genes in subcutaneous and omental adipose tissues2010

    • Author(s)
      Ugi S, Maegawa H, et al
    • Journal Title

      Obesity (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Transcription factor AP-2□ inhibits expression and secretion of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes2010

    • Author(s)
      Fuke T, Maegawa H, et al.
    • Journal Title

      International Journal of Obesity (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Transcription factor AP-2β: a negative regulator of IRS-1 gene expression2010

    • Author(s)
      Meng X, Maegawa H, et al.
    • Journal Title

      Biochem Biophys Res Commun (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] Transcription factor AP-2β: a negative regulator of IRS-1 gene expression2010

    • Author(s)
      Meng X, Kondo M, Morino K, Fuke T, Obata T, Yoshizaki, Ugi S, Nishio Y, Maeda S, Araki E, Kashiwagi A, Maegawa H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 392 Pages: 526-532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Journal Article] A. Transcription factor AP-2β : a positive regulator of MCP-1gene expression Endocrinology2009

    • Author(s)
      Kondo M, Maegawa H, Obata T, Ugi S, Ikeda K, Morino K, Nakai Y, Nishio Y, Maeda S, Kashiwagiu A
    • Journal Title

      150

      Pages: 1654-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Postprandial hyperglycemia after gastrectomy and the prediabetic state : a comparison between distal and total gastrectomy2008

    • Author(s)
      Yamamoto H, Tsuchihashi H, Akabori H, Naitoh H, Maegawa, H, Tani T.
    • Journal Title

      Surgery Today 38

      Pages: 685-90

    • NAID

      10021940322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Intima-media thickness of the carotid artery and the distribution of lipoprotein subclasses in men aged 40 to 49 years between whites in the United States and the Japanese in Japan for the ERA JUMP study2008

    • Author(s)
      Sekikawa, A, Ueshima H, Sutton-Tyrrell K, Kadowaki T, El-Saed A, Okamura T, Takamiya T, Ueno Y, Evans RW, Nakamura Y, Edmundowicz D, Kashiwagi A, Maegawa H, Kuller LH.
    • Journal Title

      Metabolism 57

      Pages: 177-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Kashiwagi A RBMX is a novel heptic transcripitinal regulator of SREBP-1c gene to high-fructose diet2007

    • Author(s)
      Takemoto T, Nishio Y, Sekine O, Ikeuchi C,Nagai Y, Maeno Y, Maegawa H, Kimura H
    • Journal Title

      FEBS letter 581

      Pages: 218-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Less subclinical atherosclerosisin Japanese men in Japan than in white men in the United States in the post World-War-II birth cohort2007

    • Author(s)
      Sekikawa A, Ueshima H, Kadowaki T, El-Saedl A, Okamura T, Takamiya T,Kashiwagi A, Edmundowicz D, Murata K,Sutton-Tyrrell1 K, Maegawa H, Evans RW, Kita Y, Kuller LH and for the ERA JUMP Study Group
    • Journal Title

      Am Jepidemiology 165

      Pages: 617-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Short-term low-dosage pioglitazone treatment improves vascular dysfunction in patients with type 2 diabetes Endocrine J.2007

    • Author(s)
      Maegawa H, Nishio Y, Nakao K, Ugi S, Maeda K, Uzu T, Kashiwagi A
    • Journal Title

      54

      Pages: 613-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinemic rats2007

    • Author(s)
      Sato Y, Nishio Y, Sekine O, Kodama K, Nagai Y, Nakamura T, Maegawa H, Kashiwagi A
    • Journal Title

      Diabetologia 50

      Pages: 481-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] 「研究成果報告書概要(欧文)」より2007

    • Author(s)
      Sato Y, Nishio Y, Sekine 0, Kodama K, Nagai Y, Nakamura T, Maegawa H, Kashiwagi A.
    • Journal Title

      Diabetologia 50

      Pages: 481-489

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2007

    • Author(s)
      Takemoto T, Nishio Y, Sekine 0, Ikeuchi C, Nagai Y, Maeno Y, Maegawa H, Kimura H, Kashiwagi
    • Journal Title

      FEBS letter 581

      Pages: 218-222

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Membrane Localization of Protein-Tyrosine Phosphatase 1B is Essential for its Activation of Sterol Regulatory Element-binding Protein-1 Gene Expression2007

    • Author(s)
      Shi K, Ugi S , Shimizu S, Sekine O, Ikeda K,Egawa K, Yoshizaki T, Nagai Y, Nishio Y,Takada T, Torii R, Kimura H, Kashiwagi, A, Maegawa H
    • Journal Title

      Biochem Biophys Res Commun 363

      Pages: 626-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Mol Endocrinol 20

      Pages: 1104-1111

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression2006

    • Author(s)
      Ikeda, K., Maegawa, H., Ugi, S., et. al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression.2006

    • Author(s)
      Ikeda K, Maegawa H, Ugi S, et al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-31253

    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] The transcription factor AP-2 beta regulates adiponectin gene expression.2006

    • Author(s)
      Ikeda K, Maegawa H, et al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-31253

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Tao Y, Maegawa H, Ugi S, et al.
    • Journal Title

      Endocrinology 147

      Pages: 1685-1696

    • Data Source
      KAKENHI-PROJECT-17590927
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Tao Y, Maegawa H, et al.
    • Journal Title

      Endocrinology 147

      Pages: 1685-1696

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006

    • Author(s)
      Tao Y, Maegawa H, et al.
    • Journal Title

      Endocrinology (in press)

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Molecular Endocrinology 20

      Pages: 1104-1111

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] The transcription factor AP-2beta causes cell enlargement and insulinresistance in 3T3-L1 adipocytes.2006

    • Author(s)
      Tao Y, Maegawa H, Ugi S, 他
    • Journal Title

      Endocrinology 147

      Pages: 1685-96

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006

    • Author(s)
      Tao Y, Maegawa H, Ugi S, et al.
    • Journal Title

      Endocrinology 147 (4)

      Pages: 1685-1685

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590927
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Uzu T, Kimura G Yamauchu A, Kanasaki M, Issiki K, Araki S, Sugimoto T, Nishio Y, Maegawa H, et al.
    • Journal Title

      J. Hypertension 24

      Pages: 1627-1632

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes2006

    • Author(s)
      Tao, Y., Maegawa, H., Ugi, S., et. al.
    • Journal Title

      Endocrinology 147

      Pages: 1685-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Molecular Endocrinology (in press)

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Kadowaki T, Sekikawa A, Okamura T, Takamiya T, Kashiwagi A, Zaky WR, Maegawa H, et al.
    • Journal Title

      Metabolism 55

      Pages: 1561-1563

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] The transcription factor AP-2β causes cell enlargement and insulin resistance in 3T3-L1 adipocytes.2006

    • Author(s)
      Tao Y, Maegawa H, et al.
    • Journal Title

      Endocrinology 147

      Pages: 1685-1696

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Transcription factor activating enhancer-binding protein-2beta. A negativeregulator of adiponectin gene expression.2006

    • Author(s)
      Ikeda K, Maegawa H, Ugi S, 他
    • Journal Title

      J Biol Chem 281

      Pages: 31245-53

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] The lranscription factor AP-2 beta regulates adiponectin gene expression.2006

    • Author(s)
      Ikeda K, Maegawa H. et al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-31253

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Kadowaki T, Serkikawa A, Murata K, Maegawa H, et al.
    • Journal Title

      International J Obesity 30

      Pages: 1163-1165

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Mol Endocrinol. 20

      Pages: 1104-1111

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Ikeda K, Maegawa H, et al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-31253

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Ikeda K, Maegawa H, Ugi S, et al.
    • Journal Title

      J Biol Chem 281

      Pages: 31245-31253

    • Data Source
      KAKENHI-PROJECT-17590927
  • [Journal Article] Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.2006

    • Author(s)
      Tsukada S, Tanaka Y, Maegawa H, et al.
    • Journal Title

      Mol Endocrinol 20

      Pages: 1104-1111

    • Data Source
      KAKENHI-PROJECT-17390262
  • [Journal Article] 「研究成果報告書概要(欧文)」より2005

    • Author(s)
      Maeda S, Tsukada S, Kanazawa A, Sekine A, Tsunoda T, Koya D, Maegawa H, et al.
    • Journal Title

      J Hum Genet. 50

      Pages: 283-292

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2005

    • Author(s)
      Hashimoto T, Nakamura T, Maegawa H, et al.
    • Journal Title

      J Biol Chem 280

      Pages: 1893-1900

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2005

    • Author(s)
      Kodama K, Nishio Y, Sekine 0, Sato Y, Egawa K, Maegawa H, Kashiwagi A.
    • Journal Title

      Am J Physiol.Cell Ph 289

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein phosphatase 2C α as a positive regulator of insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004

    • Author(s)
      Yoshizaki T, Maegawa H. et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B)Activity in 3T3-L1 Adipocyte.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H. et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein phosphatase 2C α as a positive regulator if insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004

    • Author(s)
      Yoshizaki T, Maegawa H, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes.2004

    • Author(s)
      Ugi S, Imamura T, Maegawa H, et al.
    • Journal Title

      Mol Cell Biol 24

      Pages: 8778-8789

    • Data Source
      KAKENHI-PROJECT-16046211
  • [Journal Article] 「研究成果報告書概要(欧文)」より2004

    • Author(s)
      Nagata R, Nishio Y, Sekine 0, Nagai Y, Maeno Y. Ugi S, Maegawa H, Kashiwagi A.
    • Journal Title

      J Biol Chem 279

      Pages: 29031-29042

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein phosphatase 2C α as a positive regulator of insulin sensitivity through direct activation of phospphatidylinointol 3-kinase in 3T3-L1 adipocytes2004

    • Author(s)
      Yoshizaki T, Maegawa H, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Protein-Tyrosine Phosphatase 1B Associates Insulin Receptor and Negatively Regulates Insulin Signaling without Receptor Internalization.2004

    • Author(s)
      Shi K, Egawa K, Maegawa H, et al.
    • Journal Title

      J Biochem, Tokyo 136

      Pages: 89-96

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2004

    • Author(s)
      Yoshizaki T, Maegawa H, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 22715-22726

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] 「研究成果報告書概要(欧文)」より2004

    • Author(s)
      Shi K, Egawa K, Maegawa H, et al.
    • Journal Title

      J Biochem Tokyo 136

      Pages: 89-96

    • Data Source
      KAKENHI-PROJECT-16590876
  • [Journal Article] Soy Phosphatidyl-choline Inhibited TLR4-Mediated MCP-1 Expression in Vascular Cells Atherosclerosis

    • Author(s)
      Ishikado A, Nishio Y; Yamane K, Mukose; A, Morino K, Murakami Y, Sekine O, Makino T,Maegawa H, Kashiwagi A
    • Journal Title

      (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Soy Phosphatidylcholine Inhibited TLR4-Mediated MCP-1 Expression in Vascular Cells

    • Author(s)
      Ishikada A, Maegawa H, et al.
    • Journal Title

      Atherosclerosis (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Journal Article] Transcription factor AP-2β : a positive regulator of MCP-1 gene expression

    • Author(s)
      Kondo M, Maegawa H, et al
    • Journal Title

      Endocrinology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] 外因性ケトン体投与がマウス寿命に及ぼす影響の検討2023

    • Author(s)
      富田一聖、霍田裕明、山原真子、吉林護、桑形尚吾、山原康佑、佐々木裕紀、金﨑雅美、前川聡、藤田征弘、久米真司
    • Organizer
      第66回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-23K24387
  • [Presentation] 腸管における局所ケトン体産生の役割の解明2022

    • Author(s)
      川原 良介, 藤田 征弘, 柳町 剛司, 楠井 進之介, 西村 公宏, 井田 昌吾, 佐藤 大介, 久米 真司, 森野 勝太郎, 卯木 智, 前川 聡
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-23K24387
  • [Presentation] ケトン体による哺乳類の健康寿命延長効果の検討2022

    • Author(s)
      富田 一聖, 霍田 裕明, 山原 真子, 吉林 護, 桑形 尚吾, 山原 康佑, 田中 裕紀, 前川 聡, 藤田 征弘, 久米 真司
    • Organizer
      第37回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-23K24387
  • [Presentation] 血管内皮細胞のO-GlcNAc修飾は肥満・高血糖で誘発される高血圧発症に関わる重要な因子である2021

    • Author(s)
      大角 誠一郎, 森野 勝太郎, 大橋 夏子, 石角 篤, 井田 昌吾, 一山 悠介, Rachel Perry, 藤田 征弘, 卯木 智, Gerald Shulman, 大路 正人, 前川 聡
    • Organizer
      第36回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 肥満2型糖尿病における白色及び褐色脂肪細胞のO-GlcNAc修飾の役割と新規治療標的の探索2021

    • Author(s)
      大橋 夏子, 中本 明紀子, 森野 勝太郎, 井田 昌吾, 久米 真司, 関根 理, 藤田 征弘, 卯木 智, 前川 聡
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 脂肪組織におけるO-GlcNAc修飾は肥満形成過程における脂肪組織増大に必須である2021

    • Author(s)
      中本 明紀子, 大橋 夏子, 森野 勝太郎, 井田 昌吾, Perry Rachel, Shulman Gerald, 岡本 拓也, 柳町 剛司, 佐藤 大介, 藤田 征弘, 卯木 智, 前川 聡
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 脂肪組織におけるO-GlcNAc修飾は、de novo脂肪合成を介した正常な機能維持に重要である2021

    • Author(s)
      中本 明紀子, 大橋 夏子, 森野 勝太郎, 管原 礼知安, 井田 昌吾, Perry Rachel, Shulman Gerald I., 岡本 拓也, 柳町 剛司, 佐藤 大介, 藤田 征弘, 卯木 智, 前川 聡
    • Organizer
      第36回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 腸管でのO-GlcNAc修飾はブドウ糖吸収を制御し、糖代謝の恒常性に寄与している2021

    • Author(s)
      西村 公宏, 藤田 征弘, 井田 昌吾, 柳町 剛, 西田 淳史, 安藤 朗, 森野 勝太郎, 卯木 智, 前川 聡
    • Organizer
      第36回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 腸管でのΟ-GlcNAc修飾は吸収を介して糖代謝の恒常性に寄与している2020

    • Author(s)
      西村 公宏, 藤田 征弘, 井田 昌吾, 柳町 剛司, 森野 勝太郎, 卯木 智, 前川 聡, 安藤 朗, 西田 淳史
    • Organizer
      第35回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 血管内皮細胞特異的O-GlcNAc transferase欠損マウスは高脂肪食による肥満に対し抵抗性を示す2020

    • Author(s)
      大角誠一郎、森野勝太郎、大橋夏子、石角 篤、井田昌吾、一山悠介、Perry Rachal、藤田征弘、卯木智、Shulman Gerald、大路正人、前川聡
    • Organizer
      第63回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] The role of O-GlcNAcylation in brown and white adipose tissue2020

    • Author(s)
      大橋 夏子, 森野 勝太郎, 前川 聡
    • Organizer
      第63回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 脂肪組織におけるO-GlcNAc修飾は肥満形成過程における脂肪組織増大に必須である2020

    • Author(s)
      中本 明紀子, 大橋 夏子, 森野 勝太郎, 井田 昌吾, Perry Rachel, Shulman Gerald, 岡本 拓也, 柳町 剛司, 佐藤 大介, 藤田 征弘, 卯木 智, 前川 聡
    • Organizer
      第63回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 腸管上皮細胞のO-GlcNAc修飾は栄養吸収の調整に重要である2020

    • Author(s)
      西村公宏、藤田征弘、井田昌吾、柳町剛司、西田淳史、安藤朗、森野勝太郎、卯木智、前川聡
    • Organizer
      第63回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 腸管上皮細胞のO-GlcNAc修飾は栄養吸収に重要である2019

    • Author(s)
      西村 公宏, 井田 昌吾, 森野 勝太郎, 大橋 夏子, 藤田 征弘, 今井 隆行, 西田 淳史, 杉谷 義彦, 安藤 朗, 卯木 智, 前川 聡
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 腎臓近位尿細管のO-GlcNAc修飾依存的脂肪酸代謝に着目した新規糖尿病性腎臓病治療標的の探索2019

    • Author(s)
      菅原 翔, 久米 真司, 山原 真子, 山原 康佑, 武田 尚子, 大澤 紀之, 金崎 雅美, 柳田 素子, 荒木 信一, 前川 聡
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 脂肪組織におけるO-GlcNAc修飾の欠損は白色脂肪組織の萎縮と高脂肪食摂取下での耐糖能増悪を惹起する2019

    • Author(s)
      辻 明紀子, 大橋 夏子, 森野 勝太郎, 井田 昌吾, 佐藤 大介, 藤田 征弘, 卯木 智, 前川 聡
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] Protein O-GlcNAcylation Regulates Renal Lipolysis During Fasting and Diabetes2018

    • Author(s)
      Sugahara S, Maegawa H, Kume S, Yamahara K, Yamahara M, Takeda N, Osawa N, Kanasaki M, Yanagita M, Araki S.
    • Organizer
      Kidney Week 2018 (American Society of Nephrology)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] Effect of interaction between podocyte autophagy and glomerular endothelial dysfunction on progression of diabetic nephropathy2018

    • Author(s)
      Yoshibayashi M, Kume S, Takeda N, Osawa N, Chin-Kanasaki M, Nakae Y, Yokoi H, Mukoyama M, Araki S-i, Maegawa H
    • Organizer
      The ISN Frontiers meeting 2018
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] 骨格筋におけるO-GlcNAc修飾の低下はAMPK蛋白発現の増加を伴う抗糖尿病および抗肥満作用を有する2018

    • Author(s)
      村田 幸一郎, 森野 勝太郎, 井田 昌吾, 大橋 夏子, Lemecha Mengistu, Park Shi-Young, 石角 篤, 久米 真司, Choi Cheol Soo, 関根 理, 卯木 智, 前川 聡
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 糖尿病性腎症進展における糸球体血管内皮障害とポドサイトオートファジーの関連2018

    • Author(s)
      吉林護、久米真司、武田尚子、大澤紀之、金崎雅美、中江由希、横井秀基、向山政志、荒木信一、前川聡
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] 近位尿細管のエネルギー代謝恒常性維持における蛋白質O-GlcNAc修飾の役割2018

    • Author(s)
      菅原 翔, 久米 真司, 金崎 雅美, 武田 尚子, 大澤 紀之, 柳田 素子, 荒木 信一, 前川 聡
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 近位尿細管における蛋白質O-GlcNAc修飾は脂質代謝の安定化を介して絶食時および肥満糖尿病状態での細胞障害を軽減する2018

    • Author(s)
      菅原 翔, 久米 真司, 金崎 雅美, 山原 康佑, 山原 真子, 武田 尚子, 大澤 紀之, 柳田 素子, 荒木 信一, 前川 聡
    • Organizer
      第33回 日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-18H02862
  • [Presentation] 糖尿病性腎症のポドサイト障害における糸球体血管内皮障害とポドサイトオートファジーの役割2017

    • Author(s)
      吉林 護, 久米 真司, 武田 尚子, 大澤 紀之, 金崎 雅美, 中江 由紀, 横井 秀基, 向山 政志, 荒木 信一, 前川 聡
    • Organizer
      第32回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] Association of serum n-3 polyunsaturatedfatty acids with silent cerebral vascularlesions in a Japanese male population2017

    • Author(s)
      Keiko Kondo, Hisatomi Arima, Takashi Hisamatsu, Akira Fujiyoshi, Aya Kadota, Akira Sekikawa, Sayuki Torii, Sentaro Suzuki, Akihiko Shiino, Kazuhiko Nozaki, Naoko Miyagawa, Hiroshi Maegawa, Kiyoshi Murata, Katsuyuki Miura, Hirotsugu Ueshima
    • Organizer
      21st International Epidemiological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293140
  • [Presentation] Association of serum n-3 polyunsaturatedfatty acids with silent cerebral vascularlesions in a Japanese male population2017

    • Author(s)
      Keiko Kondo, Hisatomi Arima, Takashi Hisamatsu, Akira Fujiyoshi, Aya Kadota, Akira Sekikawa, Sayuki Torii, Sentaro Suzuki, Akihiko Shiino, Kazuhiko Nozaki, Naoko Miyagawa, Hiroshi Maegawa, Kiyoshi Murata, Katsuyuki Miura, Hirotsugu Ueshima, for the SESSA Research Group
    • Organizer
      21st International Epidemiological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02528
  • [Presentation] 糖尿病に伴うポドサイト障害における食餌中アミノ酸バランスの重要性2017

    • Author(s)
      吉田 尚平, 久米 真司, 武田 尚子, 大澤 紀之, 金崎 雅美, 古家 大祐, 安達 祐介, 荒木 信一, 前川 聡
    • Organizer
      第32回日本糖尿病合併症学会
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] Role of autophagy in diabetic nephropathy and renal ketogenesis2016

    • Author(s)
      Kume S, Maegawa H
    • Organizer
      Kidney Week 2016
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-11-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] 全エクソーム解析を用いた1型糖尿病濃厚発症家系における原因遺伝子変異の探索2016

    • Author(s)
      川畑由美子、能宗伸輔、馬場谷成、廣峰義久、細道一善、前川聡、池上博司
    • Organizer
      第89回日本内分泌学会学術総会
    • Place of Presentation
      京都市(国立京都国際会館)
    • Year and Date
      2016-04-22
    • Data Source
      KAKENHI-PROJECT-26461348
  • [Presentation] Relationship of Insulin Resistance to Prevalence and Progression of Coronary Artery Calcification beyond Metabolic Syndrome in a General Population2016

    • Author(s)
      Masahiro Yamazoe, Takashi Hisamatsu, Katsuyuki Miura, Sayaka Kadowaki, Maryam Zaid, Aya Kadota, Takashi Kadowaki, Akira Fujiyoshi, Robert Abbott, Hisatomi Arima, Akira Sekikawa, Hiroshi Maegawa, Minoru Horie, Hirotsugu Ueshima
    • Organizer
      AHA EPI Lifestyle
    • Place of Presentation
      アリゾナ州、米国
    • Year and Date
      2016-03-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293140
  • [Presentation] 全エクソーム解析を用いた1型糖尿病濃厚発症家系における原因遺伝子変異の探索2016

    • Author(s)
      川畑由美子、能宗伸輔、馬場谷成、廣峰義久、細道一善、前川聡、池上博司
    • Organizer
      第89回日本内分泌学会学術総会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461348
  • [Presentation] 餓時の糖新生ならびにケトン産生における肝腎オートファジーの役割.2015

    • Author(s)
      高木 彩乃, 久米 真司, 中澤 純, 金崎 雅美, 荒木 久澄, 荒木 信一, 宇津 貴, 前川 聡.
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] 糸球体上皮細胞におけるオートファジー不全は糖尿病性腎症における蛋白尿を増悪させる.2015

    • Author(s)
      田川 安都子, 安田 真子, 久米 真司, 中澤 純, 金崎 雅美, 荒木 久澄,荒木 信一, 古家 大祐, 羽田 勝計, 宇津 貴, 前川 聡.
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] シャペロン介在性オートファジー欠損は高脂肪食負荷肥満糖尿病の発症を抑制する.2015

    • Author(s)
      安田 真子, 久米 真司, 中澤 純, 金崎 雅美, 荒木 久澄, 荒木 信一, Paul Saftig, 宇津 貴, 前川 聡.
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      山口県下関市
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] Postprandial Activation of Protein Kinase CμRegulates the Expression of Adipocytokines Via Transcription Factor AP-2β2011

    • Author(s)
      Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H.
    • Organizer
      The Annual meeting of 71st American Diabetes Association
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Presentation] The transcription factor AP-2βis a unique regulator of IRS-1 and a candidate gene for insulin resistance2010

    • Author(s)
      Kondo M, Meng X, Morino K, Yoshizaki K, Fuke T, Obata T, Ugi S, Nishio Y, Maeda S, Kashiwagi A, and Maegawa H.
    • Organizer
      The Annual meeting of 70th American diabetes association
    • Place of Presentation
      Tanpa, USA
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Presentation] New Role of Protein Kinase Cμon Adipocytokine Expression in Re-Feeding Condition Via Transcription Factor AP-2β, a Regulator of Adipocytokine Expression2009

    • Author(s)
      Kondo M, Maegawa H, Morino K, Yoshizaki T, Fike T, Obata T, Ugi S, Nioshio Y, Maeda S, Kashiwagi A.
    • Organizer
      The Annual meeting of 69th American diabetes association
    • Place of Presentation
      New Olens USA
    • Data Source
      KAKENHI-PROJECT-21591129
  • [Presentation] Safb1, an RBMX-Binding Protein, is a Newly Identified Activator in the Regulation of Hepatic SREBP-1c Gene Expression2008

    • Author(s)
      Omura Y, Nishio Y, Takemoto T, Ikeuchi C,Sekine O, Morino K, Maeno Y, Obata T, UgiS, Maegawa H, Kimura H, Kashiwagi A.
    • Organizer
      The 68th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Activation of TranscriptionFactor AP-2β Mediated by Protein Kinase Cμ Aggravates Expression of Inflammatory Adipokines in Differentiated Adipocyte2008

    • Author(s)
      Kondo M, Maegawa H, Morino K, Fuke T, Obata T, Ugi S, Nishio Y, Maeda S, Kashiwagi A
    • Organizer
      The 68th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Transcription Factor AP-2β Inhibits Glucose-Induced Insulin Secretion in Cultured Insulin-Secreting Cell Lines2008

    • Author(s)
      Tsukada S, Unoki H, Maegawa H,Kashiwagi A, Maeda S
    • Organizer
      The 68th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Transcription Factor AP-2[beta], A Novel Candidate Gene for Metabolic Syndrome,Accelerates MCP-1 Gene Expression in 3T3-L1 Adipocytes2007

    • Author(s)
      Maegawa H, Kondo M, Ikeda K, Fuke T, Nishio Y, Maeda S, Kashiwagi A
    • Organizer
      14th Japan - Korea Symposium on Diabetes Mellitus
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Amelioration of Hepatic and Visceral Fat Deposition by Pioglitazone Treatment in Normoglycemic Patients with Metabolic Syndrome2007

    • Author(s)
      Tsuchiya M, Enomoto K, Kakaoka K, Iijima H, Nishio Y, Maegawa H, Kashiwagi A
    • Organizer
      The 67th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Transcription Factor AP-2[beta],A Novel Candidate Gene for MetabolicSyndrome,Accelerates MCP-1 Gene Expression in 3T3-L1 Adipocytes.2007

    • Author(s)
      Kondo M, Maegawa H, IkedaK, 他
    • Organizer
      The 67th annual meeting of American Diabetes Association
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2007-06-24
    • Data Source
      KAKENHI-PROJECT-17390262
  • [Presentation] Transcription Factor AP-2[beta], A Novel Candidate Gene for Metabolic Syndrome, Accelerates MCP-1 Gene Expression in 3T3-L1 Adipocytes2007

    • Author(s)
      Kondo M, Maegawa H, Ikeda K, Fuke T,Nishio Y, Maeda S, Kashiwagi A
    • Organizer
      The 67th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] Common Variants of the TCF7L2 are Associated with Susceptibility to Type 2 Diabetes, But Not with the Expression of TCF7L2 in the Adipose or Plasma GLP-1 Concentrations in a Japanese Population2007

    • Author(s)
      Hayashi T, Maegawa H, Babazono T,Yamamoyto H, Hirose H, Naito H, Tani T,Kawamori R, Kaku K, Kashiwagi A, Iwamoto Y, Maeda S
    • Organizer
      The 67th annual meeting of American Diabetes Association
    • Data Source
      KAKENHI-PROJECT-19591044
  • [Presentation] 糸球体上皮細胞オートファジー不全は糖尿病性腎症における蛋白尿を増悪させる

    • Author(s)
      安田 真子, 田川 安都子, 久米 真司, 田中 敬, 金崎 雅美, 荒木 久澄, 一色 啓二, 荒木 信一, 古家 大祐, 羽田 勝計, 柏木 厚典, 宇津 貴, 前川 聡
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] Insufficient podocyte autophagy is associated with the progression of proteinuria in diabetic nephropathy.

    • Author(s)
      Mako Yasuda, Atsuko Tagawa, Shinji Kume, Yuki Tanaka, Shin-ichi Araki, Daisuke Koya, Masakazu Haneda, Takashi Uzu, Hiroshi Maegawa
    • Organizer
      The 14th Asian Pacific Congress of Nephrology (APCN2014)
    • Place of Presentation
      東京
    • Year and Date
      2014-05-14 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] The Role of Starvation-induced Autophagy in Gluconeogenesis and Ketogenesis

    • Author(s)
      Ayano Takagi, Shinji Kume, Yuki Tanaka, Hisazumi Araki, Keiji Isshiki, Shin-Ichi Araki, Takashi Uzu, Hiroshi Maegawa
    • Organizer
      American Diabetes Association (ADA) 74th Scientific Sessions
    • Place of Presentation
      サンフランシスコ, アメリカ合衆国
    • Year and Date
      2014-06-13 – 2014-06-17
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] 飢餓時の糖新生ならびにケトン産生におけるオートファジーの役割

    • Author(s)
      高木 彩乃, 久米 真司, 金崎 雅美, 荒木 久澄, 一色 啓二, 荒木 信一, 茶野 徳宏, 柏木 厚典, 宇津 貴, 前川 聡
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26293217
  • [Presentation] Podocyte Autophagy is Associated with the Progression of Proteinuria in Diabetic Nephropathy

    • Author(s)
      Mako Yasuda, Atsuko Tagawa, Shinji Kume, Yuki Tanaka, Kosuke Yamahara, Hisazumi Araki, Keiji Isshiki, Shin-ichi Araki, Daisuke Koya, Masakazu Haneda, Takashi Uzu, Hiroshi Maegawa
    • Organizer
      American Diabetes Association (ADA) 74th Scientific Sessions
    • Place of Presentation
      サンフランシスコ, アメリカ合衆国
    • Year and Date
      2014-06-13 – 2014-06-17
    • Data Source
      KAKENHI-PROJECT-26293217
  • []

  • []

  • 1.  MAEDA Shiro (50314159)
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