HAGA Hisashi 芳賀永

Researcher Number	00292045
Other IDs	https://orcid.org/0000-0001-9464-6723
Affiliation (Current)	2024: 北海道大学, 先端生命科学研究院, 教授
Affiliation (based on the past Project Information) *help	2024: 北海道大学, 先端生命科学研究院, 教授 2016 – 2022: 北海道大学, 先端生命科学研究院, 教授 2013 – 2015: 北海道大学, 先端生命科学研究科(研究院), 教授 2014: 北海道大学, 先端生命科学研究科, 教授 2014: 北海道大学, 大学院先端生命科学研究院, 教授 … More 2012: 北海道大学, 先端生命科学研究科(研究院), 准教授 2012: 北海道大学, 先端生命科学研究科, 准教授 2012: 北海道大学, 大学院・生命科学院, 准教授 2010 – 2012: 北海道大学, 大学院・先端生命科学研究院, 准教授 2010: 北海道大学, 大学院・先端生命, 准教授 2007 – 2010: Hokkaido University, Graduate School of Science, Associate Professor 2009: 北海道大学, 大学院・理学研究科, 准教授 2006: 北海道大学, 大学院理学研究院, 助教授 2002 – 2004: 北海道大学, 大学院・理学研究科, 助教授 2002: 北海道大学, 大学院・理学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Tumor biology / Biological Sciences / Basic Section 50010:Tumor biology-related / Science and Engineering / Biophysics / Cell biology Except Principal Investigator Radiation science / Biological Sciences / Basic Section 57060:Surgical dentistry-related / Basic Section 57040:Regenerative dentistry and dental engineering-related … More / Dynamics/Control / Biophysics / Structural biochemistry / Biophysics/Chemical physics / Bioinformatics/Life informatics Less
Keywords	Principal Investigator 細胞・組織 / 集団運動 / がん細胞 / コラーゲンゲル / 集団浸潤 / 電子顕微鏡 / 上皮細胞シート / ゲル基質 / メカノセンス / 細胞運動 … More / 上皮細胞 / 細胞間接着構造 / 接触追従 / ゾル基質 / 粘弾性基質 / アクトミオシン / 自己組織化 / 腸管絨毛構造 / 粘弾性培養基質 / 転写調節因子 / 転写調節因 / 炎症性反応 / 浸潤 / メカノセンシング / 上皮管腔組織 / 接着構造 / 集団性 / 細胞培養 / 組織形成 / 結合組織 / 走査型プローブ顕微鏡 … More Except Principal Investigator 細胞運動 / 細胞 / メカノバイオロジー / 発生 / 三次元 / 物理計測 / ３次元 / シミュレーション / 折り畳み / シミュレ―ション / 数理モデル / 回転 / 折り紙 / 3次元 / 形態形成 / ATF5 / apoptosis / p53 / 放射線治療 / irradiation / 放射線生物学 / 走査型プローブ顕微鏡 / ミオシン / 幹細胞 / アデノウイルスE4 / 足場材硬さ / 角化 / 運動能 / 遺伝子発現 / 口腔ケラチノサイト / 硬さ / 上皮角化 / ヤング率 / 足場材 / 口腔粘膜上皮細胞 / Nカドヘリン / メカノトランスダクション / 口腔粘膜上皮 / 培養口腔粘膜 / 非角化 / 正角化 / 口腔粘膜角化細胞 / 口腔粘膜 / 数理生物学 / バーチャル研究所 / 物理測定 / 計算科学 / ３Ｄ / 合宿 / 班会議 / CTスキャン / 工学 / 数理 / ３D / 形態 / カブトムシ / ３D形態形成 / システムバイオロジー / ３Ｄ形態 / 力学 / 外骨格 / 体節 / 昆虫 / 培養細胞の回転 / クチクラ / 3D形態形成 / transcription factor / radiosensitivity / 転写因子 / 放射線感受性 / 放射線 / atomic force microscopy / living material / cell / visco-eleastic / 表面粘性 / 表面剛性 / フォースモジュレーション法 / カンチレバー / AFM / 生体 / 粘弾性 / HIF/alpha / 低酸素 / translation / trascription / HIF-1a / HIF / UTR / 蛍光プローブ / MDシミュレーション / 細胞極性 / 構造多型性 / メカノセンサー / メカノセンシティビティ / アクチン / タンパク質結晶化 / X線結晶解析 / プラスチック検出器 / 非線形最適化 / 体幹部定位放射線照射 / プラスチック檢出器 / モンテカルロ法 / 電子線トラック解析 / 量子線シミュレーション / 低酸素細胞 / 胃癌 / 細胞遊走 / 生体の動き / 医学研究 / 動体追跡 / 細胞形態 / TGFB-1 / Radiotherapy / cell movement / cancer stem cell / radiation / HIF1-alpha / MMP / mitosis / repopulation / p16 / 力学的メモリー効果 / 力学的応答 / 細胞コロニー / リン酸化 / ホメオスタシス / 力学平衡 / システム Less

Search for novel cancer therapeutic molecular targets from the stemness induction mechanism of adenovirus E4 genes.
- Principal Investigator
  
  安田元昭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hokkaido University
Investigation of cell-cell adhesion structures and signaling pathways causing collective invasion in cancer cellsPrincipal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Investigation of the mechanism of ortho- and non-keratinization pattern using different stiffness of scaffold and its application for fabrication of tissue-engineered oral mucosa
- Principal Investigator
  
  Izumi Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Niigata University
The mechanism of contact following inducing cancer collective invasion and the verification of universalityPrincipal Investigator
- Principal Investigator
  
  Haga Hisashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
3D morphogenesis of epithelial cell sheets in vitroPrincipal Investigator
- Principal Investigator
  
  Haga Hisashi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Virtual laboratory to accelerate international collaboration on 3D morphological logic
- Principal Investigator
  
  Kondo Shigeru
- Project Period (FY)
  2015 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
3D morphologic
- Principal Investigator
  
  Kondo Shigeru
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Stiff Substrates Enhances ATF5-Signaling-Mediated Invasive Ability in Cancer CellsPrincipal Investigator
- Principal Investigator
  
  HAGA HISASHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
ゲル基質の軟らかさと粘性を利用した上皮シートの3次元組織構築Principal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
多数の細胞の力と運動がもたらす管腔構造形成のロジックPrincipal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Tension-induced conformational changes of actin filaments and their influence on actin binding and intracellular localization of myosin.
- Principal Investigator
  
  UYEDA Taro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  National Institute of Advanced Industrial Science and Technology
がん細胞は自身の生存をかけ放射線域を逃れるべく上皮間葉移行をなしうるか
- Principal Investigator
  
  西岡健
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Research for Real-time Tracking Medical Science
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Collective migration of epithelial cells induced by softness of substratesPrincipal Investigator
- Principal Investigator
  
  HAGA Hisashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Hokkaido University
力学的応答測定を利用した極微小タンパク質結晶の判別・評価法の開発
- Principal Investigator
  
  田中勲
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Hokkaido University
The secret of radiation-surviving cell : multidisciplinary approach to eradicate cancer
- Principal Investigator
  
  NISHIOKA Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Mechanical memory effect of cells in colony
- Principal Investigator
  
  KAWABATA Kazushige
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics/Chemical physics
- Research Institution
  Hokkaido University
Radiation-induced highly-malignant cancer cells: the mechanism and how to deal with it
- Principal Investigator
  
  NISHIOKA Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
細胞システムにおける「力学平衡」モデルの実証
- Principal Investigator
  
  KAWABATA Kazushige
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Hokkaido University
ナノ力学プローブ顕微鏡による結合組織の形成過程における力学的制御機構の解明Principal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Quantitative evaluation of visco-elastic distribution of living cells using scanning probe microscopy
- Principal Investigator
  
  HIRAI Yoshihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dynamics/Control
- Research Institution
  Osaka Prefecture University

[Book] 三次元培養における培養手法と周辺技術動向2019
- Author(s)
  石原誠一郎、芳賀永
- Total Pages
  197
- Publisher
  情報機構
- Data Source
  KAKENHI-PLANNED-15H05858
[Book] 医学のあゆみ2019
- Author(s)
  芳賀永
- Total Pages
  70
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PLANNED-15H05858
[Book] 三次元培養における培養手法と周辺技術動向2019
- Author(s)
  石原誠一郎，芳賀永
- Total Pages
  197
- Publisher
  情報機構
- ISBN
  9784865021684
- Data Source
  KAKENHI-PROJECT-17K07150
[Book] Chromosome Nanoscience and Technology2007
- Author(s)
  K. Kawabata, K. Nomura, K. Ikeda. O. Hoshi, D. Fukushi, H. Haga and T. Ushiki
- Publisher
  Taylor & Francis Group
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Substrate stiffness induces nuclear localization of myosin regulatory light chain to suppress apoptosis2023
- Author(s)
  Onishi Katsuya、Ishihara Seiichiro、Takahashi Masayuki、Sakai Akihiro、Enomoto Atsushi、Suzuki Kentaro、Haga Hisashi
- Journal Title
  
  FEBS Letters
  
  Volume: 597 Issue: 5 Pages: 643-656
- DOI
  10.1002/1873-3468.14592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07141, KAKENHI-PROJECT-21K07142
[Journal Article] Stiffness-Modulation of Collagen Gels by Genipin-Crosslinking for Cell Culture2023
- Author(s)
  Ishihara Seiichiro、Kurosawa Haruna、Haga Hisashi
- Journal Title
  
  Gels
  
  Volume: 9 Issue: 2 Pages: 148-148
- DOI
  10.3390/gels9020148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07141, KAKENHI-PROJECT-21K07142
[Journal Article] Matrix stiffness contributes to cancer progression by regulating transcription factors2022
- Author(s)
  Seiichiro Ishihara, Hisashi Haga
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 4 Pages: 1049-1049
- DOI
  10.3390/cancers14041049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0234, KAKENHI-PROJECT-21K07142
[Journal Article] Mammaglobin 1 mediates progression of trastuzumab‐resistant breast cancer cells through regulation of cyclins and <scp>NF‐κB</scp>2022
- Author(s)
  Kusumastuti Ratih、Kumagai Yuji、Ishihara Seiichiro、Enomoto Atsushi、Murakami Takashi、Yasuda Motoaki、Haga Hisashi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 10 Pages: 1797-1813
- DOI
  10.1002/2211-5463.13468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07141, KAKENHI-PROJECT-21K07142, KAKENHI-PROJECT-22K08437, KAKENHI-PROJECT-23K24110
[Journal Article] The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces2022
- Author(s)
  Kumagai Yuji、Nio-Kobayashi Junko、Ishihara Seiichiro、Enomoto Atsushi、Akiyama Masashi、Ichihara Ryosuke、Haga Hisashi
- Journal Title
  
  Oncogenesis
  
  Volume: 11 Issue: 1 Pages: 27-27
- DOI
  10.1038/s41389-022-00403-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07141, KAKENHI-PROJECT-21K07142
[Journal Article] Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice.2019
- Author(s)
  Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G.
- Journal Title
  
  Commun. Biol.
  
  Volume: eCollection Issue: 1 Pages: 95-95
- DOI
  10.1038/s42003-019-0336-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06837, KAKENHI-PROJECT-18K19479, KAKENHI-PLANNED-17H06432, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-16K07215, KAKENHI-PROJECT-16K07375, KAKENHI-PROJECT-18K06938, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-18H02474
[Journal Article] The intercellular expression of type-XVII collagen, laminin-332, and integrin-β1 promote contact following during the collective invasion of a cancer cell population2019
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Sumire Ishida-Ishihara, Hiromi Tachibana, Ryosuke Omori, Atsushi Enomoto, Seiichiro Ishihara, Hisashi Haga
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 514 Issue: 4 Pages: 1115-1121
- DOI
  10.1016/j.bbrc.2019.05.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07150, KAKENHI-PROJECT-17K08502
[Journal Article] Modulation and characterization of the double network hydrogel surface-bulk transition.2019
- Author(s)
  Frauenlob M, King DR, Guo H, Ishihara S, Tsuda M, Kurokawa T, Haga H, Tanaka S, Gong JP.
- Journal Title
  
  Macromolecules
  
  Volume: 52 Issue: 17 Pages: 6704-6713
- DOI
  10.1021/acs.macromol.9b01399
- NAID
  120006885161
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07059, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-17H06144
[Journal Article] Differential contributions of nonmuscle myosin IIA and IIB to cytokinesis in human immortalized fibroblasts2019
- Author(s)
  Yamamoto, K., Otomo, K., Nemoto, T., Ishihara, S., Haga, H., Nagasaki, A., Murakami, Y., Takahashi, M.
- Journal Title
  
  Experimental Cell Research
  
  Volume: 376 Issue: 1 Pages: 67-76
- DOI
  10.1016/j.yexcr.2019.01.020
- NAID
  120006803950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06200, KAKENHI-PROJECT-18K06591, KAKENHI-PLANNED-15H05953, KAKENHI-PROJECT-16H06280, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858
[Journal Article] Collective Movement and 3D Morphogenesis of Epithelial Cells Induced by Softness of the Extracellular Matrix2018
- Author(s)
  芳賀永
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 58 Issue: 4 Pages: 196-199
- DOI
  10.2142/biophys.58.196
- NAID
  130007420830
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
[Journal Article] Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells2018
- Author(s)
  Ishihara Seiichiro、Aoki Kei、Mizutani Takeomi、Amano Maho、Nishimura Shin-Ichiro、Haga Hisashi
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 43 Issue: 2 Pages: 177-185
- DOI
  10.1247/csf.18026
- NAID
  130007507045
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07150
[Journal Article] Anisotropic Multi-channel Collagen Gel (MCCG) Guides the Growth Direction of the Neurite-like Processes of PC12 Cells2018
- Author(s)
  Koh Isabel、Furusawa Kazuya、Haga Hisashi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1
- DOI
  10.1038/s41598-018-32156-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
[Journal Article] Long-term Culture of Human iPS Cell-derived Telencephalic Neuron Aggregates on Collagen Gel2018
- Author(s)
  Oyama Hiroshi、Takahashi Koji、Tanaka Yoshikazu、Takemoto Hiroshi、Haga Hisashi
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 43 Issue: 1 Pages: 85-94
- DOI
  10.1247/csf.18002
- NAID
  130006742880
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
[Journal Article] Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization2018
- Author(s)
  Wang Xiaoze、Enomoto Atsushi、Weng Liang、Mizutani Yasuyuki、Abudureyimu Shaniya、Esaki Nobutoshi、Tsuyuki Yuta、Chen Chen、Mii Shinji、Asai Naoya、Haga Hisashi、Ishida Sumire、Yokota Kenji、Akiyama Masashi、Takahashi Masahide
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 11 Pages: 3643-3656
- DOI
  10.1111/cas.13795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07150, KAKENHI-PROJECT-26221304
[Journal Article] Mesenchymal Stem Cells in Breast Cancer: Response to Chemical and Mechanical Stimuli2017
- Author(s)
  Ishihara S., Ponik S. M., Haga H.
- Journal Title
  
  Oncoscience
  
  Volume: 4 Issue: 11-12 Pages: 158-159
- DOI
  10.18632/oncoscience.381
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07150
[Journal Article] Mathematical Model of Collective Cell Migrations Based on Cell Polarity2017
- Author(s)
  M. Akiyama, T. Sushida, S. Ishida, H. Haga
- Journal Title
  
  Dev. Growth Differ
  
  Volume: 59 Issue: 5 Pages: 471-490
- DOI
  10.1111/dgd.12381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05857, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-17J06276, KAKENHI-ORGANIZER-15H05856
[Journal Article] Data set for comparison of cellular dynamics between human AAVS1 locus-modified and wild-type cells2016
- Author(s)
  Takeomi Mizutani, Hisashi Haga, Kazushige Kawabata
- Journal Title
  
  Data in Brief
  
  Volume: 6 Pages: 793-798
- DOI
  10.1016/j.dib.2015.12.053
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-26430104, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
[Journal Article] Role of ATF5 in the invasive potential of diverse human cancer cell lines2016
- Author(s)
  Akihiro Nukuda, Hiroki Endoh, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 474(3) Issue: 3 Pages: 509-514
- DOI
  10.1016/j.bbrc.2016.04.131
- NAID
  120006219898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010
[Journal Article] Conformational Plasticity of JRAB/MICAL-L2 Provides 'Law and Order'2016
- Author(s)
  A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, H.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 27 Issue: 20 Pages: 3095-3108
- DOI
  10.1091/mbc.e16-05-0332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05858, KAKENHI-PLANNED-15H05954, KAKENHI-PROJECT-15H03004, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084, KAKENHI-PROJECT-16K12872, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
[Journal Article] Receptor activator of NF-κB ligand induces cell adhesion and integrin α2 expression via NF-κB in head and neck cancers2016
- Author(s)
  T.Yamada, M. Tsuda, T. Wagatsuma, Y. Fujioka, M. Fujioka, A. O. Satoh, K. Horiuchi, S. Nishide, A. Nanbo, Y. Totsuka, H. Haga, S. Tanaka, M. Shindoh, and Y. Ohba
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 23545-23545
- DOI
  10.1038/srep23545
- NAID
  120005753715
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460545, KAKENHI-PROJECT-15K15106, KAKENHI-PUBLICLY-26115701, KAKENHI-PROJECT-26670414, KAKENHI-PROJECT-26860254, KAKENHI-PROJECT-26861539, KAKENHI-PUBLICLY-15H01248, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-15K15023, KAKENHI-PROJECT-15KK0290
[Journal Article] Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway.2015
- Author(s)
  Takemoto, T., Ishihara, S., Mizutani, T., Kawabata, K., Haga, H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0117937-e0117937
- DOI
  10.1371/journal.pone.0117937
- NAID
  120005613567
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
[Journal Article] Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate2015
- Author(s)
  Misako Imai, Kazuya Furusawa, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 14208-14208
- DOI
  10.1038/srep14208
- NAID
  120005682122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15010, KAKENHI-PROJECT-15K16330, KAKENHI-PLANNED-15H05858, KAKENHI-PUBLICLY-26106703, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
[Journal Article] Stiff Substrates Increase YAP-Signaling-Mediated Matrix Metalloproteinase-7 Expression2015
- Author(s)
  A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and H. Haga
- Journal Title
  
  Oncogenesis
  
  Volume: 4 Issue: 9 Pages: e165-e165
- DOI
  10.1038/oncsis.2015.24
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26462831, KAKENHI-PROJECT-25287106
[Journal Article] Leader Cells Regulate Collective Cell Migration via Rac Activation in the Downstream Signaling of Integrin Beta1 and PI3K2015
- Author(s)
  N. Yamaguchi, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 7656-7656
- DOI
  10.1038/srep07656
- NAID
  120005567742
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
[Journal Article] Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices2015
- Author(s)
  Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 40 Issue: 2 Pages: 61-67
- DOI
  10.1247/csf.15001
- NAID
  130005086307
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430104
[Journal Article] Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells2015
- Author(s)
  S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 4602-4614
- NAID
  120005613573
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430104
[Journal Article] Transgene Integration into the Human AAVS1 Locus Enhances Myosin II-Dependent Contractile Force by Reducing Expression of Myosin Binding Subunit 852015
- Author(s)
  T. Mizutani, R. Li, H. Haga, and K. Kawabata
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 465 Issue: 2 Pages: 270-274
- DOI
  10.1016/j.bbrc.2015.08.018
- NAID
  120005906854
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
[Journal Article] Coating extracelular matrix proteins on a (3-aminopropyl)triethoxysilane-treated glass substrate for improved cell culture.2014
- Author(s)
  Masuda, H.T., Ishihara, S., Harada, I., Mizutani, T., Ishikawa, M., Kawabata, K., Haga, H..
- Journal Title
  
  Biotechniques
  
  Volume: 56 Issue: 4 Pages: 172-179
- DOI
  10.2144/000114156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
[Journal Article] An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions2014
- Author(s)
  S.Ishihara, T.Mizutani, K.Kawabata, and H.Haga
- Journal Title
  
  Cytotechnology
  
  Volume: 09 Jul. Pages: 1-8
- NAID
  120005905602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26106702
[Journal Article] Modulation of extracellular conditions prevents the multilayering of the simple epithelium2014
- Author(s)
  T. Mizutani, K. Takeda, H. Haga, M. Todo, K. Kawabata
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: Vol. 141(5) Issue: 5 Pages: 459-471
- DOI
  10.1007/s00418-013-1176-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-25287106
[Journal Article] Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells2014
- Author(s)
  S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, H. Haga
- Journal Title
  
  Oncotarget
  
  Volume: 09 Jul Issue: 1 Pages: 1-8
- DOI
  10.1007/s10616-014-9766-4
- NAID
  120005613573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390285, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104
[Journal Article] Epithelial Sheet Folding Induces Lumen Formation by Madin-Darby Canine Kidney Cells in a Collagen Gel2014
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 8 Pages: e99655-e99655
- DOI
  10.1371/journal.pone.0099655
- NAID
  120005476150
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702
[Journal Article] Irradiation-tolerant Lung Cancer Cells Acquire Invasive Ability Dependent on Dephosphorylation of the Myosin Regulatory Light Chain2013
- Author(s)
  S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, K. Kawabata, H. Shirato and H. Haga
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Pages: 732-736
- NAID
  120005228631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Lung cancer cells that survive ionizing radiation show increased integrin α2β1- and EGFR-dependent invasiveness2013
- Author(s)
  Xue Li, Seiichiro Ishihara, Motoaki Yasuda, Takeshi Nishioka, Takeomi Mizutani, Masayori Ishikawa, Kazushige Kawabata, Hiroki Shirato, Hisashi Haga
- Journal Title
  
  PLoS One
  
  Volume: 8(8) Issue: 8 Pages: 1-12
- DOI
  10.1371/journal.pone.0070905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24390285, KAKENHI-PROJECT-25287106
[Journal Article] Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions2013
- Author(s)
  Seiichiro Ishihara, Motoaki Yasuda, Ichiro Harada, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Experimental Cell Research
  
  Volume: 319(19) Issue: 19 Pages: 2916-2927
- DOI
  10.1016/j.yexcr.2013.09.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
[Journal Article] Irradiation-tolerant lung cancer cells acquire invasive ability dependent on dephosphorylation of the myosin regulatory light chain2013
- Author(s)
  Ishihara S, Yasuda M, Nishioka T, Mizutani T, Kawabata K, Shirato H, Haga H
- Journal Title
  
  FEBS Lett
  
  Volume: 587(6) Issue: 6 Pages: 732-736
- DOI
  10.1016/j.febslet.2013.01.055
- NAID
  120005228631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-24390285
[Journal Article] Tempo-Spatial Change of Cellular Stiffness and Geometry in the Process of Developing Epithelial Cell-Cell Adhesion Measured by Atomic Force Microscopy2013
- Author(s)
  R. Tanaka, T. Mizutani, H. Haga, and K. Kawabata
- Journal Title
  
  pn. J. Appl. Phys. Conf. Proc.
  
  Volume: 1 Pages: 11004-11004
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25127701
[Journal Article] Neuronal correlates of multiple top-down signals during covert tracking of moving objects in macaque prefrontal cortex2012
- Author(s)
  Matsushima, A. & Tanaka, M.
- Journal Title
  
  J. Cogn. Neurosci
  
  Volume: 24 Issue: 01 Pages: 2043-2056
- DOI
  10.4236/cellbio.2012.11001
- NAID
  120005090600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-24106502
[Journal Article] Relationship between Diffusion-Weighted　Magnetic　Resonance Imaging and Histological Tumor Grading of Hepatocellular Carcinoma2012
- Author(s)
  Nakanishi M, Chuma M, Hige S, Omatsu T, Yokoo H, Nakanishi K, Kamiyama T, Kubota K, Haga H, Matsuno Y, Onodera Y, Kato M, Asaka M.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Issue: 4 Pages: 1302-1309
- DOI
  10.1245/s10434-011-2066-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21390369
[Journal Article] Radiation-induced cancer cell repopulation : a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line.2011
- Author(s)
  Nishioka T, Yasuda M, Takeshima T, Haga H, Miyai Y, Shibata K, Yamazaki R, Shirato H, Teduka M, Date H.
- Journal Title
  
  Cell Struct Funct. 36
  
  Pages: 13-20
- NAID
  40019163767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Radiation-induced Cancer Cell Repopulation : A possible mechanism implied by experiments using trasplantable mouse-derived sarcoma cell line2011
- Author(s)
  T.Nishioka, M.Yasuda, T.Takeshima, H.Haga, Y.Miyai, K.Shibata, H.Shirato, M, Teduka, H.Date.
- Journal Title
  
  Cell Structure and Function
  
  Volume: 36 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Active fluctuation in the cortical cytoskeleton observed by high-speed live-cell scanning probe microscopy2011
- Author(s)
  K.Tamura, T.Mizutani, H.Haga, K.Kawabata
- Journal Title
  
  Acta Biomater.
  
  Volume: 7 Issue: 10 Pages: 3766-3772
- DOI
  10.1016/j.actbio.2011.06.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21570158, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167
[Journal Article] Integrin betal-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.2010
- Author(s)
  Ishihara S, Haga H, Yasuda M, Mizutani T, Kawabata K, Shirato H, Nishioka T.
- Journal Title
  
  Biochem Biophys Res. 396
  
  Pages: 651-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Nano-mechanical Properties of Living Cells Expressing Constitutively Active RhoA Effectors2010
- Author(s)
  K. Tamura, T. Mizutani, H. Haga, and K. Kawabata
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 403巻 Issue: 3-4 Pages: 363-367
- DOI
  10.1016/j.bbrc.2010.11.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570158
[Journal Article] Integrin β1-dependent Invasive Migration of Irradiation-tolerant Human Lung Adenocarcinoma Cells in 3D Collagen Matrix2010
- Author(s)
  S.Ishihara, H.Haga, M.Yasuda, T.Mizutani, K.Kawabata, H.Shirato, T.Nishioka
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 396 Pages: 651-655
- NAID
  120002223716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Superselective high-dose cisplatin infusion with concomitant radiotherapy in patients with advanced cancer of the nasal cavity and paranasal sinuses : a single institution experience.2009
- Author(s)
  Tsutsumi K, Tsuda M, Yazawa N, Nakamura H, Ishihara S, Haga H, Yasuda M, Yamazaki R, Shirato H, Kawaguchi H, Nishioka T
- Journal Title
  
  Cell Structure and Function 34
  
  Pages: 86-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Regulation of Cellular Contractile Force in Response t Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009
- Author(s)
  T. Mizutani, K.Kawabata, Y. Koyama, M. Takahashi, H. Haga
- Journal Title
  
  Cell Motility and the Cytoskeleton (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Novel Function of Transcripion Factor ATF5 : Blockade of p53-dependent Apoptosis Induced by Ionizing Irradation2009
- Author(s)
  T. Ni shioka, Y. Miyai, H. Haga, K. Kawabata, H. Shirato, A. Homma, K. Shibata and M. Yasuda
- Journal Title
  
  Cell Structre and Function 34
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Regulation of Cellular Contractile Force in Response to Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009
- Author(s)
  T. Mizutani, K. Kawabata, Y. Koyama, M. Takahashi, and H. Haga
- Journal Title
  
  Cell Motility and the Cytoskeleton
  
  Volume: 66巻 Issue: 7 Pages: 389-397
- DOI
  10.1002/cm.20378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570158
[Journal Article] Nishioka T, Miyai Y, Haga H, Kawabata K, Shirato H, Homma A, Shibata K, and Yasuda M2009
- Author(s)
  Nishioka T, Miyai Y, Haga H
- Journal Title
  
  Cell Struct Funct 34
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Mechanical Response of Sinle Myoblasts to Various Stretching Patterns Visualized by Scanning Proe Microscoy2009
- Author(s)
  W. Mitsui, K. Tamura, T. Mizutani,Haga and K. Kawabata
- Journal Title
  
  Archivesof Histology and Cytology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Mechanical Response to Isotropic Shrinkage of Fibroblasts Measured by canning Probe Microscopy2008
- Author(s)
  T. Kawamoto, H. Haga, K. Tamura, T.Mizutani and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 47
  
  Pages: 6173-6176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007
- Author(s)
  H. Haga and K. Kawabata
- Journal Title
  
  Proceedings of the international symposium on topological aspects of critical systems and netwrks
  
  Pages: 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007
- Author(s)
  H. Haga
- Journal Title
  
  Proceedings of the international symposium on topological aspects of critical systems and networks
  
  Pages: 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Visualization of stretch-induc intracellular teal response of single fibroblasts by mechanical scaning probe microscopy2007
- Author(s)
  K. Tamura, T. Mizutani, H. Haga, K.Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 46
  
  Pages: 5631-5635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Development of a Device to Stretch Tissue-like Materials and to Measure Their Mechanical Properties by Scanning Probe Microscopy2007
- Author(s)
  T. Mizutani, H. Haga, K. Kawabta
- Journal Title
  
  Acta Biomaterialia 3
  
  Pages: 485-493
- NAID
  120000971009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscoy2007
- Author(s)
  H. Haga, M. Nagayama and K. Kawabata
- Journal Title
  
  Crent Nanoscien 3
  
  Pages: 97-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscopy2007
- Author(s)
  H. Haga
- Journal Title
  
  Current Nanoscience 3
  
  Pages: 97-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] The Role of Actin-Binding Protein Filamin A in Cellular Stiffness and Morphology Studied by Wide-Range Scanning Probe Microscopy2006
- Author(s)
  K. Kato, Y. Ohmori, T. Mizutani, H. Haga Kohashi, T. Ito, and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 45
  
  Pages: 2328-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Observation of Stiff Domain Structure on Collagen Gels by Wide-Range Scanning Probe Microscopy2006
- Author(s)
  T. Mizutani, H. Haga, K. Kato, K. Matsuda, and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 45
  
  Pages: 2353-2356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Diphosphorylation of the Myosin Regulatory Light Chain Enhancs the Tension Acting on Stress Fibers in Fibroblasts2006
- Author(s)
  T. Mizutani, H. Haga. Y. Koyama, M.Takahashi, K. Kawabata
- Journal Title
  
  Journal of Cellular Physiology 209
  
  Pages: 726-731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005
- Author(s)
  Hisashi Haga
- Journal Title
  
  Biophys.J. 88
  
  Pages: 2250-2256
- Data Source
  KAKENHI-PROJECT-14780536
[Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005
- Author(s)
  Hisashi Haga
- Journal Title
  
  Biophys.J. 88
  
  Pages: 2250-2256
- Data Source
  KAKENHI-PROJECT-15650051
[Patent] ゲルの製造方法及びコラーゲンゲル2018
- Inventor(s)
  古澤和也、芳賀永、立花真美
- Industrial Property Rights Holder
  古澤和也、芳賀永、立花真美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-007402
- Filing Date
  2018
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] STAT1活性化細胞により誘引される皮膚扁平上皮がんの集団浸潤2021
- Author(s)
  熊谷祐二, 小林純子, 石原誠一郎, 榎本篤, 芳賀永
- Organizer
  患者由来がんモデル研究会2021
- Data Source
  KAKENHI-PROJECT-21K07142
[Presentation] STAT1活性化は皮膚扁平上皮癌の集団浸潤を促進する2021
- Author(s)
  熊谷祐二, 小林純子, 石原誠一郎, 芳賀永
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07142
[Presentation] I型インターフェロン経路の亢進は扁平上皮がん由来サブクローン細胞の集団浸潤を引き起こす2021
- Author(s)
  熊谷祐二, 石原誠一郎, 芳賀永
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07142
[Presentation] がん細胞の集団浸潤：接触追従におけるintegrin-β1の機能解析2019
- Author(s)
  熊谷祐二，小林純子，石原誠一郎，芳賀永
- Organizer
  第56回日本生化学会北海道支部例会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 球形の細胞シートでみられる細胞張力依存的な変形2019
- Author(s)
  山村芳央、石原誠一郎、古澤和也、芳賀永
- Organizer
  第56回日本生化学会北海道支部例会
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] ゲル基質上の上皮細胞シートが引き起こす浸透圧勾配依存的なドーム形成2019
- Author(s)
  石原（石田）すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
- Organizer
  第56回日本生化学会北海道支部例会
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Osmotic stimuli triggered the dome formation of epithelial cells2019
- Author(s)
  Sumire Ishida-Ishihara, Masakazu Akiyama, Kazuya Furusawa, Isao Naguro, Hiroki Ryuno, Takamichi Sushida, Seiichiro Ishihara, Hisashi Haga
- Organizer
  北海道大学ライフサイエンスフォーラム 2019
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 広い細胞間隙が惹起するがん細胞の集団浸潤2019
- Author(s)
  熊谷祐二，小林純子，石原誠一郎，芳賀永
- Organizer
  第16回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019
- Author(s)
  石原（石田）すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
- Organizer
  日本生物物理学会北海道支部会例会
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019
- Author(s)
  石原（石田）すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
- Organizer
  日本生物物理学会北海道支部会例会
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] Collective Movement and 3D Morphology of Epithelial Cells on Viscoelastic Substrates2019
- Author(s)
  芳賀永
- Organizer
  GSS International Symposium（invited speaker），札幌
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019
- Author(s)
  石原（石田）すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
- Organizer
  日本生物物理学会北海道支部会例会
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] Integrin-β1 promotes contact following in collective invasion of squamous carcinoma cells2019
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
- Organizer
  第71回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] FSCN1 promotes breast cancer cell invasion via expression of LGR52019
- Author(s)
  Yuki Ito, Seiichiro Ishihara, Masayuki Kano, Hisahiro Matsubara, Hisashi Haga
- Organizer
  第71回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] Development of collagen gels with adjustable stiffness by genipin crosslinking2019
- Author(s)
  Haruna Kurosawa, Seiichiro Ishihara, Hisashi Haga
- Organizer
  7th International Life-Science Symposium
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 細胞集団に自発的な3次元形態形成を促す培養技術の開発2018
- Author(s)
  芳賀永，古澤和也
- Organizer
  帝人21世紀フォーラム
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] 細胞の集団運動と3次元形態形成2018
- Author(s)
  芳賀　永
- Organizer
  AIMaP研究会「反応拡散系と実験の融合」
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] ascin-1 promotes breast cancer cell invasion by regulating expression of LGR52018
- Author(s)
  Yuki Ito, Seiichiro Ishihara, Hisashi Haga
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 多細胞系のメカノバイオロジー2018
- Author(s)
  芳賀永
- Organizer
  CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 細胞集団に自発的な3次元形態形成を促す培養技術の開発2018
- Author(s)
  芳賀　永，古澤　和也
- Organizer
  帝人21世紀フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 細胞の集団運動と3次元形態形成2018
- Author(s)
  芳賀永
- Organizer
  AIMaP研究会「反応拡散系と実験の融合」
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] 細胞の基質牽引力と基質の粘弾性がもたらす上皮細胞の集団運動と３Ｄ形態形成2018
- Author(s)
  芳賀永
- Organizer
  第95回日本生理学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] A mathematical model of collective cell migrations based on cell polarity2018
- Author(s)
  Masakazu Akiyama,Takamaichi （Hokkaido University）,Hitomi Mori（Hokkaido University）,Sumire　（Hokkaido University）,Hisashi　Haga（Hokkaido University）
- Organizer
  11th European Conference on Mathematical and Theoretical Biology
- Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] Intercellular ECM proteins promote collective invasion in human squamous carcinoma cells through the activation of intercellular integrin-β12018
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 多細胞系のメカノバイオロジー2018
- Author(s)
  芳賀永
- Organizer
  CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] FSCN1-LGR5経路により誘導される乳がん細胞の浸潤機構2018
- Author(s)
  伊東祐紀, 石原誠一郎, 芳賀永
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 細胞の基質牽引力と基質の粘弾性がもたらす上皮細胞の集団運動と３Ｄ形態形成2018
- Author(s)
  芳賀　永
- Organizer
  第95回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Activation of intercellular integrin-β1 promotes collective invasion in human squamous carcinoma cells2018
- Author(s)
  Yuji Kumagai, Seiichiro Ishihara, Hisashi Haga
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] Collective Movement and 3D Morphogenesis of Epithelial Cells Responding to Viscoelastic Substrates2018
- Author(s)
  Hisashi Haga
- Organizer
  Japan-Toronto Morphogenesis Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 多細胞系のメカノバイオロジー2018
- Author(s)
  芳賀永
- Organizer
  CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] The role of intercellular gaps for collective invasion in cancer cell population2018
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
- Organizer
  第70回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] A self-propelled particle model for representing collective cell migrations2018
- Author(s)
  T. Sushida, H. Mori, S. Ishida, H.Haga, M. Akiyama
- Organizer
  13th SIAM East Asian Section Conference 2018: June 22-25, 2018.
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] Mechanosensitive Response of Cancer and Epithelial Cells Induced by in/on Viscoelastic Substrates2018
- Author(s)
  芳賀　永
- Organizer
  The 33rd Biomechanics Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] Epithelial cell polarity essential for collective migration and 3D morphogenesis of cell sheets2017
- Author(s)
  Hisashi Haga
- Organizer
  The 18th RIES-HOKUDAI International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] Collective movement and 3D morphogenesis of epithelial cells induced by viscoelasticity of the extracellular matrix2017
- Author(s)
  Hisashi HAGA
- Organizer
  Japan-UCI Meeting on 3D Morphogenesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Substrate stiffness enhances cancer　progression through transcription factor YAP and ATF52017
- Author(s)
  Hisashi Haga
- Organizer
  HU-KSMCB Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] The role of integrin-α2β1 in the collective invasion of human A431 squamous carcinoma cells2017
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Hisashi Haga
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] The role of integrins in the collective invasion of human A431 squamous carcinoma cells2017
- Author(s)
  Yuji Kumagai, Hisashi Haga
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] メカニカルなストレスによって促進されるがん細胞の悪性化2017
- Author(s)
  芳賀　永
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] Epithelial cell polarity essential for collective migration and 3D morphogenesis of cell sheets2017
- Author(s)
  芳賀　永
- Organizer
  The 18th RIES-HOKUDAI International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Investigation of the cell-cell adhesion mechanism of A431 cells with collective invasive potential2017
- Author(s)
  Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
- Organizer
  5th International Life-Science Symposium
- Data Source
  KAKENHI-PROJECT-17K07150
[Presentation] 基底膜に覆われた細胞群の回転運動を表現するための数理モデル2017
- Author(s)
  須志田隆道,森瞳,石田すみれ,古澤和也,芳賀永,秋山正和
- Organizer
  2017年度応用数学合同研究集会
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] Role of ATF5 in cancer cell invasion of several diverse human cancer cell lines2016
- Author(s)
  Akihiro Nukuda, Motoaki Yasuda, and Hisashi Haga
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016
- Author(s)
  芳賀　永
- Organizer
  第54回日本生物物理学会年会シンポジウム
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と３次元形態形成2016
- Author(s)
  芳賀　永
- Organizer
  第54回日本生物物理学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05856
[Presentation] Fascin-1 promotes cancer cell invasion via activation of Stat32016
- Author(s)
  Toshiki Takahashi, Akihiro Nukuda, Masayuki Kano, Hisahiro Matsubara, and Hisashi Haga
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 3D morphogensis of epithelial cells responding to viscoelasticity of the extracellular matrix2016
- Author(s)
  Hisashi Haga
- Organizer
  Japan-Austria joint meeting "Understanding the logic behind developmental dynamics
- Place of Presentation
  IST, Klosterneuburg（Austria）
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 転写因子ATF5による多様ながん細胞株の浸潤促進2016
- Author(s)
  温田晃弘, 安田元昭, 水谷武臣, 川端和重, 芳賀永
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016
- Author(s)
  芳賀永
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Activating transcription factor 5 promotes invasion of cancer cells via transcriptional activation of integrins2015
- Author(s)
  Akihiro Nukuda, Seiichiro Ishihara, Motoaki Yasuda, and Hisashi Haga
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Activating transcription factor 5 promotes cancer cell invasion through transcriptional activation of integrins2015
- Author(s)
  Akihiro Nukuda, Hiroki Endo, Seiichiro Ishihara, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, and Hisashi Haga
- Organizer
  2015 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  サンディエゴ（アメリカ合衆国）
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 基質の硬さによって促進される大腸がん細胞の悪性化：転写因子YAPを介した基質分解酵素MMP-7の発現亢進2015
- Author(s)
  温田晃弘, 石原誠一郎, 水谷武臣, 中村公則, 綾部時芳, 川端和重, 芳賀永
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1,integrin beta1,and PI3K2014
- Author(s)
  N.Yamaguchi, T.Mizutani, K.Kawabata, and H.Haga
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂（奈良県春日野町）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PUBLICLY-26106702
[Presentation] Epithelial sheet folding triggers a luminal structure of Madin-Darby canine kidney cells in a collagen gel2014
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, N. Ishikawa, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
- Organizer
  International Symposium on 3D Tissue Fabrication
- Place of Presentation
  東京大学生産技術研究（東京都）
- Data Source
  KAKENHI-PUBLICLY-25127701
[Presentation] 3D tulip hat-like morphogenesis on deformable substrate induced by cellular contractile force2014
- Author(s)
  M. Imai, T. Mizutani, K. Kawabata, and H. Haga
- Organizer
  International Symposium on 3D Tissue Fabrication
- Place of Presentation
  東京大学生産技術研究（東京都）
- Data Source
  KAKENHI-PUBLICLY-25127701
[Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Integrin α2 dependent increased invasiveness of lung adenocarcinoma cells that survived 10 Gy ionizing radiation2012
- Author(s)
  李雪、石原誠一郎、山田泰士、安田元昭、水谷武臣、川端和重、西岡健、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] EGFR and Integrin α2β1 Dependent Invasiveness of Lung Adenocarcinoma Cells that Survived 10 Gy Ionizing Radiation2012
- Author(s)
  X. Li, S. Ishihara, M. Yasuda, T. Mizutani, K. Kawabata, T. Nishioka, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター（米国）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and composition of extracellular matrix2012
- Author(s)
  芳賀永
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012
- Author(s)
  石田すみれ、田中良昌、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] A stiff substrate activates transcription factor NF-B and increases the adhesion area in cancer cells2012
- Author(s)
  石原誠一郎、安田元昭、芳賀永
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館（北海道）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Substrate stiffness enhances MMP-7 expression and ECM degradation in cancer cells2012
- Author(s)
  佐々木千絵、桝田浩孝、中村公則、綾部時芳、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and Composition of extracellular matrix2012
- Author(s)
  芳賀永
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡市)(招待講演)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012
- Author(s)
  今井美沙子、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012
- Author(s)
  今井美沙子、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Invasive Migration ofIrradiation Survived Human LungAdenocarcinoma Cells in 3D Matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム(招待講演)
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity and cell migration in folding phenomena of epith elial sheets2012
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター(米国,サンフランシスコ)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012
- Author(s)
  石田すみれ、田中良昌、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity and cell migration in folding phenomena of epithelial sheets2012
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター（米国）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール(北海道)(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大(東京都) 招待講演
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大(東京都) 招待講演
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール(北海道)(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Substrate stiffness regulates NF-k B expression and malignancy in cancer cells2011
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] NF-k B expression in cancer cells regulated by substrate stiffness2011
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Substrate stiffness regulates NF-k B expression and activity in cancer cells2011
- Author(s)
  S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
- Organizer
  第51回米国細胞生物学会年会
- Place of Presentation
  Colorado Convention Center (USA)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 3次元培養環境においてみられる放射線照射後に生残した肺がん細胞の浸潤機構2010
- Author(s)
  石原誠一郎、安田元昭、武島嗣英、水谷武臣、川端和重、西岡健、芳賀永
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Integrin Dependent Invasive Mmigration in 3D Collagen Matrix of Human Lung Adenocarcinoma Cells that Survived 10Gy Iirradiation2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
- Organizer
  札幌国際がんシンポジウム2010
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクール
- Place of Presentation
  北海道医療大学・サテライトキャンパス
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学(当別町) 招待講演
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学(石狩) 招待講演
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクールin Sapporo
- Place of Presentation
  北海道医療大学サテライトキャンパス(石狩) 招待講演
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクールin Sapporo
- Place of Presentation
  北海道医療大学・サテライトキャンパス(札幌市) 招待講演
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Enhancement of NE- EIB Expression and Malignancy of Cancer Cells Induced by Substrate Stiffness2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
- Organizer
  第50回米国細胞生物学会年会
- Place of Presentation
  Pennsylvania Convention Center(アメリカ)
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Invasive Mechanism of Lung Adenocarcinoma Cells Revealed by 3D Collagen Culture2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
- Organizer
  第57回マトリックス研究会大会
- Place of Presentation
  秋田拠点センター・アルヴェ(秋田)
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸) 招待講演
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 基質の硬さがもたらす転写因子NF-κBの発現2010
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第5回メカノセンシング研究会
- Place of Presentation
  京都大学(京都)
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸市) 招待講演
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009
- Author(s)
  芳賀永
- Organizer
  第49回米国細胞生物学会年会
- Place of Presentation
  サンディエゴコンベンションセンター
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009
- Author(s)
  H.Haga, et al.
- Organizer
  第49回米国細胞生物学会年会
- Place of Presentation
  米国・サンディエゴ市・コンベンションセンター
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007
- Author(s)
  芳賀永
- Organizer
  日本表面科学会第27回表面科学講演大会
- Place of Presentation
  東京
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-18340122
[Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007
- Author(s)
  芳賀永
- Organizer
  日本表面科学会第27回表面科学講演大会招待講演
- Place of Presentation
  東京都
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-18340122
[Presentation] Invasive ability is regulated by activating transcription factor 5 in high invasive cancer cells
- Author(s)
  H. Endoh, S. Ishihara, T. Nishioka, M. Yasuda, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Activating transcription factor 5 enhances radioresistance and malignant phenotypes in lung cancer cells
- Author(s)
  S. Ishihara, M. Yasuda, T. Nishioka, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1, integrin beta1, and PI3K
- Author(s)
  N. Yamaguchi, T. Mizutani, K. Kawabata, and H.i Haga
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂（奈良県春日野町）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PUBLICLY-25127701
[Presentation] Substrate stiffness enhances expression of matrix metalloproteinase 7 via myosin phosphorylation in colon cancer cells
- Author(s)
  A. Nukuda, S. Ishihara, K. Nakamura, T. Ayabe, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104

1. KAWABATA Kazushige (20261274)

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HAGA Hisashi 芳賀 永

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Investigation of cell-cell adhesion structures and signaling pathways causing collective invasion in cancer cellsPrincipal Investigator

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The mechanism of contact following inducing cancer collective invasion and the verification of universalityPrincipal Investigator

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3D morphogenesis of epithelial cell sheets in vitroPrincipal Investigator

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Stiff Substrates Enhances ATF5-Signaling-Mediated Invasive Ability in Cancer CellsPrincipal Investigator

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ゲル基質の軟らかさと粘性を利用した上皮シートの3次元組織構築Principal Investigator

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多数の細胞の力と運動がもたらす管腔構造形成のロジックPrincipal Investigator

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Collective migration of epithelial cells induced by softness of substratesPrincipal Investigator

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HAGA Hisashi 芳賀永