MURAKAMI Yukihisa 村上幸寿

… Alternative Names

MURAKAME Yukihisa 村上孝寿

村上孝壽ムラカミユキヒサ

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Researcher Number	00377269
Affiliation (based on the past Project Information) *help	2007 – 2010: University of Toyama, Institute of Natural Medicine, Assistant Professor 2006: 富山大学, 助手 2005: 富山大学, 和漢医薬学総合研究所, 助手
Review Section/Research Field	Except Principal Investigator General internal medicine (including Psychosomatic medicine) / Psychiatric science
Keywords	Except Principal Investigator M-CSF / BNIP-3 / experimental ischemia / gene expression / cholinergic system / endogenous factor(s) / chotosan / Kampo Medicine / cognitive deficit / chronic hypoperfusion … More / mRNA expression / Hochuekkito / depressive disorder / dementia / Chotosan / Wakan-yaku / NG108-15 / CSF / ウイリアムズ症候群 / 抗うつ / セロトニン / C6グリオーマ / 遺伝子発現変化 / 両方向性調節 / 記憶学習 / 和漢処方 / 当帰芍薬散 / 認知症 / 釣藤散 / うつ病 / 補中益気湯 / 和漢薬 / special cognitive deficit / saikokeishito / gene analysis / macrophage colony刺激因子 / Senescence-accelerated mouse / emotional disoders / anti-dementia drug / mediator(s) / ischemia / platelet derived growth factor / aging / neuroplasticity / vascular endothelial growth factor / Kampo medicine / dementia model / 加齢 / 脳虚血 / メディエータ / 漢方薬 / 認知症モデル / 内在性因子 / DNAアレイ解析 / ペントバルビタール / 神経栄養因子 / Ergl / 遺伝子発現 / ベンゾジアゼピン系薬物 / γアミノ酪酸神経系 / 情動行動障害 / 攻撃行動 / 長期隔離飼育ストレス Less

Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine
- Principal Investigator
  
  MATSUMOTO Kinzo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
攻撃行動制御因子の単離同定と神経生理機能に関する研究
- Principal Investigator
  
  MATSUMOTO Kinzo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  University of Toyama
Search, identification, and functional analysis of target molecules for cerebrovascular dementia treatment using bioactivities of Kampo medicines
- Principal Investigator
  
  MATSUMOTO Kinzo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Identification of the intrinsic molecules which are involved in the generation of disease, and the analysis of the molecular mechanisms and functions, by using Wakan-yaku, Japanese traditional systematized medicine
- Principal Investigator
  
  TOHDA Michihisa
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] 治療学:特集「漢方の教育とEBM」痴呆マウスと釣藤散2006
- Author(s)
  村上孝寿, 松本欣三
- Publisher
  ライフサイエンス出版(株)(In press)
- Data Source
  KAKENHI-PROJECT-17390208
[Journal Article] Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain2010
- Author(s)
  Mingmalairak S, Tohda M, Murakami Y, Matsumoto K.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 636-640
- NAID
  130000248011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390197
[Journal Article] Enhanced expression of BCL2/adenovirus EIB 19-kDa-interacting protein 3 mRNA, a candidate for intrinsic depression-related factor, and effects of imipramine in the frontal cortex of stressed mice.2010
- Author(s)
  Tohda M, Mingmalairak S, Murakami Y, Matsumoto K.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 53-57
- NAID
  130000140191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390197
[Journal Article] 脳とくすり-脳血管性認知症と漢方薬を中心に2009
- Author(s)
  松本欣三, 趙碕, 村上孝寿, 東田道久
- Journal Title
  
  脳21 12
  
  Pages: 114-122
- Data Source
  KAKENHI-PROJECT-20390197
[Journal Article]2009
- Author(s)
  Cuia H-S., Murakami Y., Hori H., Zhao Q., Obi R., Matsumoto K.
- Journal Title
  
  Biol.Pharm.Bull. 32
  
  Pages: 79-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390197
[Journal Article] Chotosan enhances Macrophage colony-stimulating factor mRNA expression in the ischemic rat brain and C6Bu-1 glioma cells2007
- Author(s)
  Obi, R., Tohda, M., Zhao, Q., Obi, N., Hori, H., Murakami, Y., Goto, H., Shimada, Y., Ochiai, H., Matsumoto, K
- Journal Title
  
  Biol. Pharm. Bull 30
  
  Pages: 2250-2256
- NAID
  110006546420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus2007
- Author(s)
  Sumanont, Y, Murakami, Y, Tohda, M, Vajragupta, O, Watanabe, H, Matsumoto, K
- Journal Title
  
  Biol. Pharm. Bull 30
  
  Pages: 1732-1739
- NAID
  110006380259
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Chotosan, a kampo formula, ameliorates chronic cerebral hypoperfusion-induced deficits in object recognition behaviors and central cholinergic systems in mice2007
- Author(s)
  Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y., Matsumoto, K
- Journal Title
  
  J Pharmacol Sci 103
  
  Pages: 360-373
- NAID
  10024313412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by maneanese complexes of curcumin and diacetylcurcumin2006
- Author(s)
  Sumanont, Y., Murakami, Y., Tohda, M., Vajragupta, O., Watanabe, H., Matsumoto, K
- Journal Title
  
  Life Sci 78
  
  Pages: 1884-1891
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action2006
- Author(s)
  Vajragupta, O, Boonyarat, C, Murakami, Y, Tohda, M, Musatmoto, K, Olson, AJ, Watanabe, H
- Journal Title
  
  Free Radic Res 40
  
  Pages: 685-695
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Supressive effects of isorhynchophyline on 5-HT2A receptor function in the brain: Behavioral and electrophysiological studies2005
- Author(s)
  Matsumoto, K., Morishige, R., Murakami,Y., Tohda, M., Takayama, H., Sakakibara, I., Watanabe, H
- Journal Title
  
  Eur. J. Pharmacol 517
  
  Pages: 191-199
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Preventive effect of chotosan, a kampo medicine, on transient ischemia-induced learning deficit is mediated by stimulation of muscarinic ml but not nicotinic receptor2005
- Author(s)
  Zhao, Q., Murakami, Y., Tohda, M., Watanabe, H., Matsumoto, K
- Journal Title
  
  Biol Pharm Bull 28
  
  Pages: 1873-1878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Hayashi, H., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H2005
- Author(s)
  Hayashi, H., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H
- Journal Title
  
  Biol. Pharm. Bull 28
  
  Pages: 744-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M_1 receptor.2005
- Author(s)
  Murakami Y. et al.
- Journal Title
  
  Pharmacology, Biochemistry and Behavior 81
  
  Pages: 616-625
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor2005
- Author(s)
  Murakami, Y., et. al.
- Journal Title
  
  Pharmacol. Biochem. Behav 81
  
  Pages: 616-625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390208
[Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor2005
- Author(s)
  Murakami, Y., Zhao, Q., Harada, K., Tohda, M., Watanabe, H., Matsumoto, K
- Journal Title
  
  Pharm. Biochem. Behay 81
  
  Pages: 616-625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Effects of Choto-san and its related constituents on endogenous antioxidant systems2005
- Author(s)
  Mahakunakorn, P., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H
- Journal Title
  
  Biol. Pharm. Bull 28
  
  Pages: 53-57
- NAID
  110003665770
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Social isolation stress-induced oxidative damage in mouse brain and its modulation by majonoside-R2, a Vietnamese ginseng saponin2005
- Author(s)
  Huong, N.T., Murakami, Y., Tohda, M., Watanabe, H., Matsumoto, K
- Journal Title
  
  Biol Pharm Bull 28
  
  Pages: 1389-1393
- NAID
  110003666433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor2005
- Author(s)
  Murakami Y. et al.
- Journal Title
  
  Pharmacol.Biochem.Behav. 81
  
  Pages: 616-625
- Data Source
  KAKENHI-PROJECT-17390208
[Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor.2005
- Author(s)
  Murakami, Y., 他計6名
- Journal Title
  
  Pharm. Biochem. Behav. 81
  
  Pages: 616-625
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390209
[Presentation] マウスの嗅球摘出により誘発される記憶障害にないする抑肝散の改善効果2010
- Author(s)
  林田未希, Salin Mingmalairak, 村上孝寿, Zhao Q., 東田道久, 松本欣三
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 一過性脳虚血誘発のラット海馬グルタミン酸遊離増加に対する黄連解毒湯の作用2010
- Author(s)
  堀仁美, 村上孝寿, 趙〓, 東田道久, 松本欣三
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] Innovative Research in Natural Products fos Sustainable Development2009
- Author(s)
  村上孝寿, 崔虎山, 堀仁美, 趙〓, 小尾龍右, 松本欣三
- Organizer
  The 8th JSPS-NRCT Joint Seminar
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] Neuroprotective effect of berberine on ischemic damage in hippocampal slice cultures and its putative mechanism (s) of the action2009
- Author(s)
  Yukihisa Murakami, et al.
- Organizer
  8th JSPS-NRCT Joint Seminar on “Innovative Research in Natural Products fos Sustainable Development"
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 恐怖条件付けによるマウスのフリージング行動に対する数種漢方方剤の影響2009
- Author(s)
  村上孝寿, 山田麻利名, 東田道久, 柴原直利, 松本欣三
- Organizer
  第26回和漢医薬学会大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] 脳虚血に対するベルベリンの保護効果とその作用機序-海馬切片培養系及び脳内透析法による検討2008
- Author(s)
  村上孝寿, 崔虎山, 堀仁美, 小尾龍右, 松本欣三
- Organizer
  第25回和漢医薬学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] マウス海馬切片培養系における虚血性障害に対するベルベリンの影響2008
- Author(s)
  崔虎山, 村上孝寿, 堀仁美, 趙〓, 小尾龍右, 松本欣三
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390197
[Presentation] Neuropharmacological evidence for availability of a Kampo medicine Chotosan in clinical treatment of vascular dementia: From behavior to molecular aspect2007
- Author(s)
  Matsumoto, K., Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y
- Organizer
  Joint Symposium: Evidence-based Approach to Traditional Medicine and Modern Medicine
- Place of Presentation
  Beijing
- Year and Date
  2007-06-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Presentation] 学習性無力マウスの回避行動障害に対するdesipramineおよびfluoxetine反復投与の効果2007
- Author(s)
  村上孝寿, 他計3名
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Presentation] Neuroprotective Activities of Manganese Complexes of Curcumin and Diacetylcurcumin in A Kainic Acid-induced Neurotoxicity Model of Rats2006
- Author(s)
  Matsumoto, K., Sumanont, Y., Murakami, Y., Tohda, T., Vajragupta, O., Watanabe, H
- Organizer
  The 7th JSPS-NRCT Joint Seminar
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Presentation] Choto-san, a Kampo formula, ameliorates spatial learning behaviour deficits and central cholinergic dysfunction caused by chronic cerebral hvnonerfusion in mice2006
- Author(s)
  Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y., Matsumoto, K
- Organizer
  The 7th JSPS-NRCT Joint Seminar
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390209
[Presentation] Effects of Chotosan on brain ischemia- induced spatial cognitive deficits in mice2005
- Author(s)
  Murakami, Y., et. al.
- Organizer
  The 16th Symposium on Natural Medicine Development and Applications
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390208
[Presentation] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor2005
- Author(s)
  Murakami, Y., et. al.
- Organizer
  The 22nd Annual meeting of medical and pharmaceutical Society for Wakan-Yaku
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390208
[Presentation] 脳虚血誘発のマウスの空間認知障害に対する釣藤散の効果2005
- Author(s)
  村上孝寿, 他計5名
- Organizer
  第16回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390209

1. MATSUMOTO Kinzo (10114654)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. TOHDA Michihisa (20207525)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. TANAKA Ken (60418689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TSUNEYAMA Koichi (10293341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SIBAHARA Naotoshi (10272907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SAKURAI Hideaki (00345571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOMATSU Katsuko (50225570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOHDA Chihiro (10272931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
9. OBI Ryousuke (60401816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 後藤博三 (40313598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

MURAKAMI Yukihisa 村上 幸寿

MURAKAME Yukihisa 村上 孝寿

村上 孝壽 ムラカミ ユキヒサ

Research Projects

Research Products

Co-Researchers

Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

攻撃行動制御因子の単離同定と神経生理機能に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search, identification, and functional analysis of target molecules for cerebrovascular dementia treatment using bioactivities of Kampo medicines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the intrinsic molecules which are involved in the generation of disease, and the analysis of the molecular mechanisms and functions, by using Wakan-yaku, Japanese traditional systematized medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 治療学:特集「漢方の教育とEBM」痴呆マウスと釣藤散2006

Author(s)

Publisher

Data Source

[Journal Article] Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Enhanced expression of BCL2/adenovirus EIB 19-kDa-interacting protein 3 mRNA, a candidate for intrinsic depression-related factor, and effects of imipramine in the frontal cortex of stressed mice.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 脳とくすり-脳血管性認知症と漢方薬を中心に2009

Author(s)

Journal Title

Data Source

[Journal Article]2009

Author(s)

Journal Title

Data Source

[Journal Article] Chotosan enhances Macrophage colony-stimulating factor mRNA expression in the ischemic rat brain and C6Bu-1 glioma cells2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Chotosan, a kampo formula, ameliorates chronic cerebral hypoperfusion-induced deficits in object recognition behaviors and central cholinergic systems in mice2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by maneanese complexes of curcumin and diacetylcurcumin2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action2006

Author(s)

Journal Title

Description

Data Source

MURAKAMI Yukihisa 村上幸寿

MURAKAME Yukihisa 村上孝寿

村上孝壽ムラカミユキヒサ