TAKAMATSU Manabu 高松学

Researcher Number	00750366
Affiliation (Current)	2025: 公益財団法人がん研究会, がん研究所病理部, 主任研究員
Affiliation (based on the past Project Information) *help	2024 – 2025: 公益財団法人がん研究会, がん研究所病理部, 主任研究員 2020 – 2023: 公益財団法人がん研究会, がん研究所病理部, 研究員 2019 – 2022: 公益財団法人がん研究会, 有明病院病理部, 医員 2019: 公益財団法人がん研究会, 研究所病理部, 研究員 2018: 公益財団法人がん研究会, がん研究所病理部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 人工知能 / 病理組織画像 / 発現解析 / 予後予測 / 画像解析 / 病理組織 / 膵癌 / 病理 / 大腸鋸歯状病変 / microRNA … More / FFPEサンプル / RNA抽出 / 癌化 / mRNA / マイクロRNA / 癌化予測 / SSA/P / 大腸 … More Except Principal Investigator 免疫染色 / 消化器外科 / 食道胃接合部腺癌 / AI診断 / TCGA / 上部消化管腺癌 / 分子亜型 / TP53 / ディープラーニング / 化学療法選択 / Caveolin-1発現 / 膵癌EUS-FNA検体 / 効果予測 / カベオリン / 微小環境 / 化学療法 / 膵癌 / 分子探索・プロファイリング / 分子プロファイリング / 生理機能解析 / 病理形態解析 / ゲノム編集 / モデル動物作製 / マイクロアレイ / 予後 / 内臓脂肪 / 補体 / 食道扁平上皮癌 / 肥満 / 食道癌 / BMI / C4 / C3 / Complement factor / Esophaegal cancer / Obese / Exome解析 / 非EBV非MSI-high腫瘍 / 網羅的解析 / 免疫チェックポイント / 細胞傷害性T細胞 / 制御性T細胞 / 腫瘍組織型 / 免疫回避機構 Less

Development of a Novel Prognostic Prediction Approach for Gastroenteropancreatic Neuroendocrine Tumors Through the Integration of Pathological Imaging and Genomic DataPrincipal Investigator
- Principal Investigator
  
  高松学
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Japanese Foundation for Cancer Research
Caveolin-1 expression in pancreatic cancer EUS-FNA specimens and establishment of clinical basis for chemotherapy selection
- Principal Investigator
  
  大庭篤志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
ディープラーニングによる上部消化器腺癌の分子亜型診断モデルの構築
- Principal Investigator
  
  渡邊雅之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
先端モデル動物支援プラットフォーム
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
Prognostic prediction and heterogenetic visualization of pancreatic cancer by histologic and genomic analysisPrincipal Investigator
- Principal Investigator
  
  Takamatsu Manabu
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Japanese Foundation for Cancer Research
Molecular mechanism and novel target of diffuse histological type of non-EBV/non-MSI-H esophagogastric junction adenocarcinoma
- Principal Investigator
  
  IDA Satoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Novel therapeutic targets based on the interactional analaysis between fat cell and cancer cells in the patients with esophageal cancer
- Principal Investigator
  
  WATANABE Masayuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Prediction of carcinogenesis for colonic serrated lesions with micro RNA analysisPrincipal Investigator
- Principal Investigator
  
  TAKAMATSU Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Japanese Foundation for Cancer Research

All 2024 2022 2021

All Journal Article Presentation

[Journal Article] FOXP3+/CD8+ ratio associated with aggressive behavior in RUNX3-methylated diffuse esophagogastric junction tumor2024
- Author(s)
  Maruyama Suguru、Imamura Yu、Toihata Tasuku、Haraguchi Ikumi、Takamatsu Manabu、Yamashita Makiko、Nakashima Yuichiro、Oki Eiji、Taguchi Kenichi、Yamamoto Manabu、Mine Shinji、Okamura Akihiko、Kanamori Jun、Nunobe Souya、Sano Takeshi、Kitano Shigehisa、Noda Tetsuo、Watanabe Masayuki
- Journal Title
  
  Cancer Science
  
  Volume: 116 Issue: 1 Pages: 178-191
- DOI
  10.1111/cas.16373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08908, KAKENHI-PROJECT-23K08101, KAKENHI-PROJECT-24K11901, KAKENHI-PROJECT-24K11921
[Journal Article] Caveolin-1 expression is a predictor of survival and recurrence patterns in resected pancreatic ductal adenocarcinoma2024
- Author(s)
  Hirose Yuki、Oba Atsushi、Takamatsu Manabu、Hamada Tsuyoshi、Takeda Tsuyoshi、Suzuki Tatsunori、Maekawa Aya、Kitano Yuki、Sato Shoki、Kobayashi Kosuke、Omiya Kojiro、Ono Yoshihiro、Sato Takafumi、Ito Hiromichi、Sasaki Takashi、Ozaka Masato、Takeuchi Kengo、Sasahira Naoki、Inoue Yosuke、Wakai Toshifumi、Takahashi Yu
- Journal Title
  
  Pancreatology
  
  Volume: 24 Issue: 7 Pages: 1021-1030
- DOI
  10.1016/j.pan.2024.10.001
- Data Source
  KAKENHI-PROJECT-24K11858
[Journal Article] Development and Validation Study of the Prognostic Impact of Deep Learning-Determined Myxoid Stroma After Neoadjuvant Chemotherapy in Patients with Esophageal Squamous Cell Carcinoma2024
- Author(s)
  Kouzu Keita、Tsujimoto Hironori、Imamura Yu、Kajiwara Yoshiki、Nearchou Ines P.、Einama Takahiro、Takamatsu Manabu、Haraguchi Ikumi、Watanabe Takanori、Horiguchi Hiroyuki、Kishi Yoji、Tsuda Hitoshi、Watanabe Masayuki、Ueno Hideki
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 31 Issue: 9 Pages: 6300-6308
- DOI
  10.1245/s10434-024-15626-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K11901, KAKENHI-PROJECT-24K11921
[Journal Article] Prediction of Recurrence Pattern of Pancreatic Cancer Post-Pancreatic Surgery Using Histology-Based Supervised Machine Learning Algorithms: A Single-Center Retrospective Study2022
- Author(s)
  Hayashi K, Ono Y, Takamatsu M, Oba A, Ito H, Sato T, Inoue Y, Saiura A, Takahashi Y.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 29 Issue: 7 Pages: 4624-4634
- DOI
  10.1245/s10434-022-11471-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15393
[Journal Article] Immunogenic characteristics of microsatellite instability‐low esophagogastric junction adenocarcinoma based on clinicopathological, molecular, immunological and survival analyses2021
- Author(s)
  Imamura Y, Toihata T, Haraguchi I, Ogata Y, Takamatsu M, Kuchiba A, Tanaka N, Gotoh O, Mori S, Nakashima Y, Oki E, Mori M, Oda Y, Taguchi K, Yamamoto M, Morita M, Yoshida N, Baa H, Mine S, Nunobe S, Sano T, Noda T, Watanabe M
- Journal Title
  
  International Journal of Cancer
  
  Volume: 148 Issue: 5 Pages: 1260-1275
- DOI
  10.1002/ijc.33322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09231, KAKENHI-PROJECT-20K09046, KAKENHI-PROJECT-18K08638, KAKENHI-PROJECT-21K08766, KAKENHI-PROJECT-21K16477
[Presentation] HoxD遺伝子座を含む染色体逆位はマウスの雌性不妊を引き起こす2024
- Author(s)
  平野克樹、岩田悟、高松学、長原美樹、岩本隆司
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] Molecular subtype と食道浸潤長からみた食道胃接合部腺癌の至適リンパ節郭清2021
- Author(s)
  今村裕、蟹江恭和、丸山傑、坂本啓、藤原大介、岡村明彦、金森淳、高松学、布部創也、吉田直矢、沖英次、森田勝、森正樹、馬場秀夫、佐野武、渡邊雅之
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09231

1. WATANABE Masayuki (80254639)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 今村裕 (70583045)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. IDA Satoshi (80583038)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 森誠一 (10334814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 武川睦寛 (30322332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 井上純一郎 (70176428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中村卓郎 (00180373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高田昌彦 (00236233)

# of Collaborated Projects: 1 results

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9. 清宮啓之 (50280623)

# of Collaborated Projects: 1 results

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10. 八尾良司 (80291095)

# of Collaborated Projects: 1 results

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11. 山崎聡 (50625580)

# of Collaborated Projects: 1 results

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12. 荒木喜美 (90211705)

# of Collaborated Projects: 1 results

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13. 阿部学 (10334674)

# of Collaborated Projects: 1 results

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14. 山田泰広 (70313872)

# of Collaborated Projects: 1 results

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15. 伊川正人 (20304066)

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16. 高橋智 (50271896)

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17. 真下知士 (80397554)

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18. 小林和人 (90211903)

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19. 小林憲太 (70315662)

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20. 井上謙一 (90455395)

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21. 豊國伸哉 (90252460)

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22. 二口充 (60275120)

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23. 神田浩明 (90260067)

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24. 上野正樹 (30322267)

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25. 宮崎龍彦 (80239384)

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26. 鈴木周五 (60363933)

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27. 宮川剛 (10301780)

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28. 高雄啓三 (80420397)

# of Collaborated Projects: 1 results

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29. 池田和隆 (60281656)

# of Collaborated Projects: 1 results

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30. 井手聡一郎 (30389118)

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31. 新田淳美 (20275093)

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32. 尾藤晴彦 (00291964)

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33. 虫明元 (80219849)

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34. 小山内実 (90286419)

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35. 旦慎吾 (70332202)

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36. 馬島哲夫 (30311228)

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37. 田代悦 (00365446)

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38. 堂前直 (00321787)

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39. 松本健 (60222311)

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40. 川田学 (20300808)

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41. 田原栄俊 (00271065)

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42. 掛谷秀昭 (00270596)

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43. 澤崎達也 (50314969)

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44. 松浦正明 (40173794)

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45. 大庭篤志 (70740257)

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46. 佐々木隆 (10569106)

# of Collaborated Projects: 1 results

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47. 廣瀬雄己 (10737365)

# of Collaborated Projects: 1 results

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48. 笹平直樹 (30401102)

# of Collaborated Projects: 1 results

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49. 高橋祐 (30595517)

# of Collaborated Projects: 1 results

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50. 井上陽介 (50597747)

# of Collaborated Projects: 1 results

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51. 田口健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 中島雄一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 山本学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAMATSU Manabu 高松 学

Research Projects

Research Products

Co-Researchers

Development of a Novel Prognostic Prediction Approach for Gastroenteropancreatic Neuroendocrine Tumors Through the Integration of Pathological Imaging and Genomic DataPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Caveolin-1 expression in pancreatic cancer EUS-FNA specimens and establishment of clinical basis for chemotherapy selection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ディープラーニングによる上部消化器腺癌の分子亜型診断モデルの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

先端モデル動物支援プラットフォーム

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Prognostic prediction and heterogenetic visualization of pancreatic cancer by histologic and genomic analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism and novel target of diffuse histological type of non-EBV/non-MSI-H esophagogastric junction adenocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapeutic targets based on the interactional analaysis between fat cell and cancer cells in the patients with esophageal cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of carcinogenesis for colonic serrated lesions with micro RNA analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] FOXP3+/CD8+ ratio associated with aggressive behavior in RUNX3-methylated diffuse esophagogastric junction tumor2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Caveolin-1 expression is a predictor of survival and recurrence patterns in resected pancreatic ductal adenocarcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development and Validation Study of the Prognostic Impact of Deep Learning-Determined Myxoid Stroma After Neoadjuvant Chemotherapy in Patients with Esophageal Squamous Cell Carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of Recurrence Pattern of Pancreatic Cancer Post-Pancreatic Surgery Using Histology-Based Supervised Machine Learning Algorithms: A Single-Center Retrospective Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunogenic characteristics of microsatellite instability‐low esophagogastric junction adenocarcinoma based on clinicopathological, molecular, immunological and survival analyses2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] HoxD遺伝子座を含む染色体逆位はマウスの雌性不妊を引き起こす2024

Author(s)

Organizer

Data Source

TAKAMATSU Manabu 高松学