KIMURA Minoru 木村穣

… Alternative Names

木村穰キムラミノル

木村穣キムラミノル

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Researcher Number	10146706
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022 – 2023: 東海大学, 医学部, 客員教授 2019 – 2021: 東海大学, 総合医学研究所, 特任教授 1995 – 2018: 東海大学, 医学部, 教授 1996: 東海大学, 医学部・分子生命学科, 教授 1996: School of Medicine, Tokai University, Department of Genetic Information, Profess, 医学部・分子生命科学, 教授 … More 1995: 東海大学医学部, 分子生命科学, 教授 1994: 東海大, 医学部, 助教授 1993: 東海大学, 医学部, 助教授 1991: 東海大学, 医学部・DNA生物学, 助教授 1989 – 1991: Tokai Univ. School of Med. Associate Prof., 医学部, 助教授 1989: 東海大学, 医学部DNA生物学教室, 助教授 1989: 東海大学, 医学部・DNA生物学教室, 助教授 1987 – 1988: 東海大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Developmental biology / Basic Section 48040:Medical biochemistry-related / Risk sciences of radiation and chemicals / 広領域 / Genetics/Genome dynamics / 内科学一般 / Molecular biology / Medical genome science / Risk sciences of radiation/Chemicals / Human genetics / Biological Sciences / Applied animal science … More Except Principal Investigator … More Morphological basic dentistry / Human pathology / Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related / Environmental impact assessment / General internal medicine(including psychosomatic medicine) / Developmental mechanisms and the body works / Environmental risk control and evaluation / Laboratory animal science / Surgical dentistry / Developmental biology / 広領域 / Kidney internal medicine / Ophthalmology / Circulatory organs internal medicine / Developmental biology / Public health/Health science / General internal medicine (including Psychosomatic medicine) / Laboratory animal science / Biological Sciences / Applied genomics / Applied animal science / Applied animal science Less
Keywords	Principal Investigator 遺伝子発現 / 母性RNA / マウス / 翻訳制御 / 初期胚 / maternal RNA / gene expression / mouse / cDNA / 受精卵 … More / 着床前初期胚 / SSEC-D / tsec / 神経障害エステラーゼ / トランスジェニックマウス / 遺伝子操作マウス / 接合型遺伝子発現 / 卵形成 / poly(A) / 疾患モデル / polyA / cDNAライブラリー / M32 / B1 / 遺伝子工学 / 遺伝子改変 / CRISPR / 有機リン / PNPLA6 / 疾患感受性遺伝子 / シックハウス症候群 / poly(A)化 / 卵母細胞 / 転写後調節 / 神経機能 / リン脂質代謝 / Purkinje / Autophaggy / Sick House Syndrome / Purkinje cell / Organophosphate / lipid metabolism / Organophophate / Behavior / Brain Function / Gene Knockout Mice / Transgenic Mice / 高発現細胞 / NTE-DDVP / 眼球運動 / Transgenic mouse / 神経障害標的エステラーゼ / 神経障害エステラーぜ / 質量分析 / 複合体 / Acetylcholine Esterase / 複合体解析 / Myelin formation / Model for diseases / Embryo manipulation / Genetic engineering / Antisense DNA / Transgenic mice / 疾患モデル動物 / ミエリン塩基性タンパク質 / ミエリン形成 / 発生工学 / アンチセンスDNA / embryo / cDNA Library / 接合子型遺伝子発現 / ポリA鎖伸長 / 伸長 / ポリA鎖 / 翻訳 / fertilized egg / zygotic expression / poly(A) addition / traslation / preimplantation / 発現調節 / 接合子 / poly(A)付加 / deisease model / microsatellite / transgenic mouse / Psoriasis Vulgaris / Behcet's disease / susceptibility gene / genome anlaysis / human genome / ベーテェット病 / SNP / 尋常性乾鮮 / ヒト疾患 / マイクロサテライト / 尋常性乾癬 / ベーチェット病 / ゲノム解析 / ヒトゲノム / polyA addition / early embryo / 発現制御 / 一過性伸長 / MOD2 / マウス初期胚 / polyA付加 / マスウ / early embryos / ポリA配列 / 多分化能 / 主要組織適合抗原 / MHC / 遺伝子変異 / 発現抑制 / HLA抗原 / 再生 / HLA / 移植片拒絶 / ベータ２m遺伝子 / HLA発現低下 / NK細胞 / 遺伝子発現制御 / CRISPR/Cas9 / 遺伝子欠失 / HLA遺伝子 / 移植片拒絶回避 / iPS細胞 / 化学物質過敏症 / OPIDN / モデルマウス / ゲノム編集 / ROSA26 / esterase / PNPLA6 gene / 疾患モデルマウス / 巨大DNA領域 / II型制限酵素 / 微量DNA / 相同組換え / 血液 / BAC / 疾患感受性領域 / TAR法 / 制限酵素 / ETクローニング / DNA抽出 / poly(A)鎖付加 / 胚盤胞 / loxP系 / Cre / レポーター遺伝子 / 着床前胚 / 細胞系譜 / lacZ / EGFP / Cre-loxP系 / 飜譯制御 / ポリA付加 / RNA鎖伸長 / Polyadenylation / Cytoplasmic Polyadenylation / CPE / poly A / マウス受精卵 / 接合子型RNA … More Except Principal Investigator トランスジェニックマウス / マウス / ノックアウトマウス / Sez12 / 個体発癌 / Tbx1 / Dgcr2 / 22q11.2欠失症候群 / 遺伝子導入 / TGF-beta / 頭蓋底軟骨結合 / DGCR2 / Transgenic mouse / 形態形成 / 体細胞突然変異 / トランスクリプトーム解析 / 遺伝子解析 / DGCR2遺伝子 / TGF-betaシグナル / Df1 / 肥大軟骨細胞 / 遺伝学 / ミュータジェネシス / 口腔扁平上皮癌 / NOTCH1 / FOXL2 / αSU / MHC / HLA-B51 / 疾患モデル動物 / オンコジーン / BMP / GFP / 顎形態形成 / バイオマーカー / マウス遺伝学 / 関節炎 / 病態モデル / 実験動物学 / 疾患モデル / 疾患感受性 / HLA / GFPノックイン / 転写因子 / 下垂体 / 受精卵 / 遺伝子治療 / IL-12 / 突然変異 / 中枢神経系 / cーHaーras / ヒト疾患モデル / メチルニトロソウレア / PCR / 大規模細胞変異解析 / RNAシーケンス / DNAシーケンス / NOTCH / エクソーム解析 / 次世代シーケンス / PDXモデル / OSCC / Df1マウス / GFPノックインマウス / オミクス解析 / モデルマウス / バイオインフォーマティクス / 進化 / バイオインフォマティクス / 進化学 / 自然発生突然変異 / 動物モデル / SDG / 次世代シーケンシング / ゲノム解析 / 次世代影響評価 / ゲノム学 / 量的遺伝学 / 集団遺伝学 / 次世代リスク評価 / 変異率 / 自然変異 / 生物多様性 / 全ゲノム解読 / 実験分子進化学 / ゲノム機能解析 / 環境変異原 / Dgcr2ノックアウトマウス / 顎顔面形態形成 / 軟骨細胞 / 初代軟骨細胞 / TBX1 / X型コラーゲン / 初代培養軟骨細胞 / 腎機能 / 慢性腎疾患 / 漢方薬 / 血清クレアチニン濃度 / シスプラチンAKI / シスプラチン / 血清クレアチニン / 血清尿素窒素 / 急性腎障害 / 黄耆 / CRF / optogenetics / コルチコステロン / 光遺伝学 / トレーニング / 室傍核 / コルチコトロピン放出因子 / 眼球運動 / 運動学習 / ストレス / 経皮暴露 / 薬剤反応性 / 環境質定量化・予測 / 有害化学物質 / 発症リスク評価法 / 皮膚内代謝 / フタル酸エステル / シックハウス症候群 / ENUミュータジェネシス / 変異マウス / 自然炎症 / HRAS / 変異解析 / HRAS変異 / NOTCH1変異 / 大規模遺伝子解析 / Mutation analysis / Oral cancer / transcription / translation / poly (A) tail / maternal RNA / gene expression / embryo / fertilized oocyte / mouse / cDNA Library / 翻訳制御 / 接合子型遺伝子発現 / ポリA鎖伸長 / 着床前初期胚 / 翻訳 / 転写 / ポリA鎖 / 母性RNA / 遺伝子発現 / 初期胚 / Adenoma / Pituitary / αサブユニット / サンドスタチンレセプター / CDKインヒビター / PTTG / Pit1 / 下垂体前葉ホルモン / 下垂体腺腫 / 腫瘍 / endotherial cells / non-classical MHC class I / classical MHC class I / Immuno-Histochemistry / Expression analysis / Central Nervous System / H2 molecule / H2遺伝子 / 血管内皮細胞 / 非古典的クラスI分子 / 古典的クラスI分子 / 免疫染色 / 発現解析 / H2分子 / Bioartificial Kidney / Artifickal membrane / Gene transfection / Aquaporin 1 DNA / LLC-PK1 cells / Hybrid artificial tubules / Tubular epithelial cells / アクアポリン1 / ハイブリッド人工尿細胞 / バイオ人工腎臓 / 人工膜 / アクアポリン1遺伝子 / LLC-PK_1細胞 / ハイブリッド人工尿細管 / 尿細管上皮細胞 / Uveitis / Vogt-Koyanagagi-Harada's disease / molecular genetics / immune-mediate infammatory diseases / microsatellite / MICA^★009 / Behcet's disease / HLA-B51トランスジェニックマウス / MICA / ヒトゲノムプロジェクト / ぶどう膜炎 / Vogt-小柳-原田病 / 分子遺伝学 / 眼免疫病 / マイクロサテライト / MICA*009 / ベーチェット病 / IL- 1α / Disease-model / Concentric hypertrophy / Heart-specific / Cre-loxP system / 過剰発現 / IL-1 / IL-1α / 疾患モデルマウス / 肥大型心筋症 / 心臓特異的 / Cre-loxP系 / positional cloning / dorsal-ventral patterning / morphogenesis / medaka / ポジショナル・クローニング / 形態形式 / ポジショナルクローニング / 背腹軸 / メダカ / Somatic mutation / Tumor / c-Ha-ras gene / Exposure experiment / Cigarette smoke / 感受性 / トランスジェックマウス / 体細胞変化 / 発ガン / c-Ha-ras遺伝子 / 曝露実験 / シガレット煙 / ミエリン塩基性タンパク質 / アミロイド沈着 / 実験動物 / 挿入突然変異 / アンチセンスRNA / アンチセンスDNA / 高発癌系統 / 組織特異的発癌 / 血管内皮細胞腫 / ヒトc-Ha-ras / 腺腫瘍 / 脾臓腫瘍 / ヒトcーHaーras / BMPシグナル / TGF-βシグナル / 軟骨細胞分化 / ノックインGFP / 顎顔面骨格形成 / Neural crest cell / CT / 鼻中隔 / 関節軟骨 / 軟骨内骨化 / 22q11欠失症候群 / Sez12遺伝子 / マイクロアレー / マイクロアレイ / 遺伝子 / センノシド / 線虫 / 寿命延長 / 抗加齢 / ダイオウ / ENU / 炎症 / リン酸化 / シグナル伝達 / 自己炎症性症候群 / 相関解析 / ジェノタイピング / リシークエンシング / ゲノム / データベース / 多型 / ゲノタイピング / ゲノム多様性 / 次世代シークエンサー / DiGeorge症候群 / 顎顏面領域 / ノッケアウトマウス / 鼻中隔湾曲症 / 咬合異常 / 神経冠細胞 / 形態異常 / 顎顔面領域 / Anterior Pituitar / Cell to cell interaction / Immunohistochemistry / NOTCH ligand / Pituitary Adenoma / Translocation / Wnt signaling / NOTCH receptor / Pitutary Adenoma / Anterior Pituitary / Wntシグナル / Notchシグナル / haplotype / ET cloning / homologous recombination / Bacterial Artificial Chromosome(BAC) / RMCE / recombineering / ES cell / chosen locus / single copy Tg / association study / gene targeting / lacZ / 濾胞 / EGFP / プラスミド / electroporation / 卵巣 / ベータガラクトシダーゼ / DNA / RT-PCR / 胚盤胞 / トランスジェニック / 精巣 / リポソーム / サイトカイン療法 / 癌 / バイスペシフィック抗体 / キラーT細胞 / ヘルパーT細胞 / がん治療 / がん免疫 / p53 / セロトニン受容体 / H-ras / グルタミン酸受容体 / ドーパミン受容体 / ras / 免疫系 / ジーンターゲッティング / 標的遺伝子組換え / 高脂血症 / 高血圧 / キメラマウス / 標的遺伝子置換法 / ジ-ンタ-ゲッティング / モデル動物 / アザチロシン / ジメチルベンズアントラセン(DMBA) / メチルニトロソウレア(MNU) / オンコジ-ン / WTー1遺伝子 / NFー1遺伝子 / Hox3.5遺伝子 / p53の両側欠損 / がん抑制遺伝子の検証 / ES細胞 / 相同組換え法 / 血管肉腫 / 化学発癌 / 乳頭腫 / 遺伝子標的導入法 / アンチセンス / 家族性アミロイドポリニューロパチー / 生物機能モデル / 血管内皮腫 / オリゴヌクレオチドプローブ / 点突然変異 / ヒトHーras遺伝子 Less

Analyses for the new function of the neuropathy target esterase using genetically engineered mice.Principal Investigator
- Principal Investigator
  
  Kimura Minoru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tokai University
Expression characteristics of Sez12 gene, the murine homolog of DGCR2, in chondrocytes from 22q11.2 deletion syndrome model with knocked-in GFP
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokai University
Analysis of carcinogenesis mechanism using PDX model based on exome analysis in Japanese oral cancer
- Principal Investigator
  
  Ota Yoshihide
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokai University
Development of comprehensive identification of spontaneous mutations based on whole genome sequencing applicable for the assessment of low-dose mutagens.
- Principal Investigator
  
  Gondo Yoichi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Environmental impact assessment
- Research Institution
  Tokai University
Establishment of assessment method for onset risk of sick house syndrome based on skin metabolism
- Principal Investigator
  
  Hatanaka Tomomi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental risk control and evaluation
- Research Institution
  Josai University
  Tokai University
Influences of stresses to motor learning
- Principal Investigator
  
  KATOH Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental mechanisms and the body works
- Research Institution
  Tokai University
Elucidation of the mechanism of renal dysfunction improvement by Kampo treatment
- Principal Investigator
  
  ARAI Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Tokai University
The Sez12, mouse homolog of DGCR2 gene encoding within 22q11.2, contributes to enchondral ossification in skull base
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University
Oral cancer model of functional mutations in NOTCH1 and HRAS
- Principal Investigator
  
  OTA Yoshihide
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokai University
Towards the diagnosis method for the toxicity of organophosphorusPrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tokai University
Developing the Universal iPS cell lines using genetic engineering systemPrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  Tokai University
Sez12 gene contributes to the chondrocytes differentiation by modulating TGF-ß signaling during postnatal maxillofacial development.
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University
Molecular analysis of mast cell activation in mouse models for autoinflammatory syndromes and its use for anti-inflammatory drug development
- Principal Investigator
  
  ABE Koichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Analysis for the function of the candidate gene of Sick House Syndrome and development of disease model mousePrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tokai University
HLA genome diversity analyses by resequencing
- Principal Investigator
  
  SHIINA Takashi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokai University
Analysis of the inflammatory mechanisms caused by the Ali18 mutation in molecular and cellular levels
- Principal Investigator
  
  ABE Koichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Construction of molecular basis and clinical application of Kampo medicine
- Principal Investigator
  
  ARAI Makoto
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Tokai University
Molecular analysis of craio-facial abnormalities found in the Sez12 knockout mice
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University
Molecular pathology for functional differentiation of human pituitary adenomas : New development of NOTCH signaling pathway.
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Sez12ノックアウトマウスを用いた顎形態形成に関する研究
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University
疾患感受性ハプロタイプを検証する為の新規BACトランスジェニック手法の開発
- Principal Investigator
  
  OHTSHUKA Masato
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Tokai University
ヒト少量血液からの対象ゲノム領域クローニング新手法の開発Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Tokai University
Molecular pathology of the functional differentiation of the pituitary adenoma
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Cytoplasmic polyadenylation and deadenylation of maternal RNAs from fully-grown oocyte to 2-cell embryo stages in the mouse
- Principal Investigator
  
  SAKURAI Takayuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Depart.of Organ Regeneration, Graduate School of Med, Shinshu Univ.
  Tokai University
マウス卵巣への効率的な遺伝子導入法の開発
- Principal Investigator
  
  佐藤正宏
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Tokai University
Research for the Cellular RNA Elongation in Mouse Fertilized EggPrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  School of Medicine, Tokai University
Functional analysis of MHC class I molecules in the neuronal cells of central nervous
- Principal Investigator
  
  INOKO Hidetoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Tokai University
受精後の初期発生プログラムに連動するポリA鎖伸長母性RNAの網羅的アプローチPrincipal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokai University
マウス初期胚母性RNAの時期特異的ポリ(A)鎖伸長の意義Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokai University
Studies on molecular genetic mechanism of intractable immune-mediated inflammatory diseases of the eye by genomic analyses
- Principal Investigator
  
  OHNO Shigeaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  HOKKAIDO UNIVERSITY
  Yokohama City University
Development of Hybrid Bioartificial Tubules using Tubular Epithelial Cells
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
マウス初期胚発生における母性RNAのStage-specificな構造的変化Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokai University
Cre-loxP系を応用した哺乳動物胚における新しい細胞系譜解析法の開発Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Tokai University
Identification of the genes for human diseases by the nucleotide analyses in wide range and developing the model mouse for themPrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Tokai University
Production and analysis of transgenic mice exhibiting concentric hypertrophy in a heart using Cre-loxP system
- Principal Investigator
  
  SATO Masahiro
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University
Gene expression in early mouse embryo and its regulationPrincipal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Tokai University
マウス初期胚における母性RNA情報の伝達と消長Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokai University
Mapping and cloning of the Da mutant gene defective dorsal-ventral patterning
- Principal Investigator
  
  OZATO Kenjiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  NAGOYA UNIVERSITY
マウス初期胚におけるmRNA情報の変化とその制御Principal Investigator
- Principal Investigator
  
  木村穣
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
個体への簡便で効率的な遺伝子導入法の確立
- Principal Investigator
  
  佐藤正宏
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Tokai University
標的遺伝子組換えによる突然変異体の作成とその生体機能の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
  Kyushu University
ANALYSIS OF GENES EXPRESSED IN PREIMPLANTATION MOUSE EMBRYOS.Principal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Developmental biology
- Research Institution
  SCHOOL OF MEDICINE,TOKAI UNIVERSITY
IL-12と癌ペプチドを用いた担癌生体内腫瘍特異的免疫の分子制御法の確立
- Principal Investigator
  
  西村孝司
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
Studies on cigarettes smoke carcinogenesis using trensgenic mouse with human c-Ha-ras gene contained somatically activated transgenes.
- Principal Investigator
  
  MATUKI Hideaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Tokai University Junior College of Nursing and Medical Technology
Analysis of Genes Expressed in.2 cell-stage.Mouse.Embryos.Principal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokai University
腫瘍局所免疫(local help)の分子制御法の開発
- Principal Investigator
  
  西村孝司
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
相同組換え遺伝子導入による発癌機構の研究
- Principal Investigator
  
  井川洋二
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Medical and Dental University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
導入オンコジ-ンの体細胞突然変異誘発による個体発癌の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokai University
導入オンコジ-ンの体細胞突然変異によって起こる個体発癌の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokai University
活性化オンコジーンを導入したトランスジェニックマウスによる個体発癌の研究
- Principal Investigator
  
  KATSUKI Motoya
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokai University
Analysis of gene function using transgenic mice harboring antisense DNA.Principal Investigator
- Principal Investigator
  
  KIMURA Minoru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  School of Medicine, Tokai University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
活性化オンコジーンを導入したトランスジェニックマウスによる個体発癌の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokai University
活性化オンコジーンを導入したトランスジェニックマウスによる個体発癌の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokai University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University

[Book] シックハウス症候群マニュアル2013
- Author(s)
  木村穣
- Publisher
  東海大学出版会
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] マウスを用いた動揺病を引き起こす前庭 ─ 視覚環境条件の探索とその予防へのアプローチ2024
- Author(s)
  加藤明、中谷七海、志村史子、木村穣
- Journal Title
  
  臨床環境医学
  
  Volume: 32 Pages: 77-84
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06847
[Journal Article] ヒト神経障害エステラーゼ遺伝子導入細胞の樹立と有機リンの影響について2023
- Author(s)
  加賀谷徹、本杉奈美、水谷晃子、坂部貢、加藤明、田中正史、木村穣
- Journal Title
  
  臨床環境医学
  
  Volume: 32 Pages: 18-27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06847
[Journal Article] Potential UV-Protective Effect of Freestanding Biodegradable Nanosheet-Based Sunscreen Preparations in XPA-Deficient Mice2022
- Author(s)
  Hatanaka Tomomi、Ramphai Khampeeraphan、Takimoto Shun、Kanda Hiromi、Motosugi Nami、Kimura Minoru、Mabuchi Tomotaka、Oyama Midori、Takeuchi Tomoharu、Okamura Yosuke
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 2 Pages: 431-431
- DOI
  10.3390/pharmaceutics14020431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06847
[Journal Article] The mouse homolog of DGCR2 gene encoding within 22q11.2 contributes to enchondral ossification in skull base and its defect causes the severity in 22q11.2 deletion syndrome2018
- Author(s)
  Kajiwara, K., Aoyama, K., Uchibori, M., Ota, Y., Kimura, M., Tanigaki, K. and Elizabeth Illingworth
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery
  
  Volume: 76 (10) Issue: 10 Pages: e71-e72
- DOI
  10.1016/j.joms.2018.06.152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11460
[Journal Article] Microneedle pH Sensor: Direct, Label-Free, Real-Time Detection of Cerebrospinal Fluid and Bladder pH2017
- Author(s)
  Ganesh Kumar Mani, Kousei Miyakoda, Asuka Saito, Yutaka Yasoda, Kagemasa Kajiwara, Minoru Kimura, Kazuyosi Tsutiya.
- Journal Title
  
  ACS Appl. Mater. Interfaces
  
  Volume: 9 Issue: 26 Pages: 21651-21659
- DOI
  10.1021/acsami.7b04225
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11460
[Journal Article] AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through an ATG7-independent pathway2017
- Author(s)
  Akatsuka Hisako、Kuga Shuhei、Masuhara Kaori、Davaadorj Odontuya、Okada Chisa、Iida Yumi、Okada Yoshinori、Fukunishi Nahoko、Suzuki Takahiro、Hosomichi Kazuyoshi、Ohtsuka Masato、Tanaka Masafumi、Inoue Ituro、Kimura Minoru、Sato Takehito
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 491 Issue: 4 Pages: 1098-1104
- DOI
  10.1016/j.bbrc.2017.08.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-15K12215
[Journal Article] A mutation in NOTCH1 ligand binding region detected in patients with oral squamous cell carcinoma reduces NOTCH1 oncogenic effect2017
- Author(s)
  M. Uchibori, Ken-ichi Aoyama, Y. Ota, K. Kajiwara, M. Tanaka, M. Kimura
- Journal Title
  
  Oncology Reports
  
  Volume: 38 Issue: 4 Pages: 2237-2242
- DOI
  10.3892/or.2017.5870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K20614, KAKENHI-PROJECT-15K11302
[Journal Article] Identification of a novel HLA-C allele, HLA-C*03:313, in a Japanese Indivisual2016
- Author(s)
  Suzuki, S., Sato, T., Akatsuka, H., Kimura, M. and Shiina, T.
- Journal Title
  
  HLA
  
  Volume: 87 Pages: 186-187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290066
[Journal Article] Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice2016
- Author(s)
  Shin-ichiro Mugikura, Akira Katoh, Satoshi Watanabe, MinoruKimura, and KagemasaKajiwara
- Journal Title
  
  Biochemistory and Biophysics Reports
  
  Volume: 5 Pages: 120-126
- DOI
  10.1016/j.bbrep.2015.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462876
[Journal Article] Chemical Sensitivity-The Frontier of Diagnosis and Treatment2016
- Author(s)
  Sakabe, K., Kimura, M., Terayama, H., Tsunoda, M., Miyajima, E., Takano, H., Azuma, K., Mizukoshi, A., Matsuda, T., Mori, C., Kawakami, S., Miyata, M., Ishikawa, S. and Aizawa, Y.
- Journal Title
  
  Japanese Journal of Clinical Ecology
  
  Volume: 25 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12215
[Journal Article] Identification of a novel HLA-C allele, HLA-C*03:313, in a Japanese individual. HLA(Tissue Antigen)2016
- Author(s)
  S. Suzuki T. Sato, A. Akatsuka1, M. Kimura1 and T. Stiina
- Journal Title
  
  HLA (Tissue Antigen)
  
  Volume: 87 Issue: 3 Pages: 186-187
- DOI
  10.1111/tan.12750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290066
[Journal Article] シックハウス症候群原因物質の経皮吸収に及ぼすNTE活性の影響2015
- Author(s)
  畑中朋美、荻野瑛里奈、山村勇貴、本杉奈美、竹内絵理、坂部貢、杉野雅浩、従二和彦、木村穣
- Journal Title
  
  臨床環境医学
  
  Volume: 24 Pages: 88-93
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12215
[Journal Article] Novel cancer vaccination system based on human endo-β-N-Acetyl glucosaminidase gene delivery2014
- Author(s)
  Watanabe S, Haraguchi S, Nakamura S, Sakurai T, Mugikura S, Kajiwara K, Minoiru K, Sato M
- Journal Title
  
  Journal of Glycobiology
  
  Volume: 3 Issue: 01 Pages: 1-1
- DOI
  10.4172/2168-958x.1000106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-25462876
[Journal Article] Interaction between carbon nanotubes and human cell.2014
- Author(s)
  Tsuchiya, K., Iimori, S., Kajiwara, K. and Kimura, M.
- Journal Title
  
  Precision Engineering
  
  Volume: 38 Pages: 116-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C.2014
- Author(s)
  Umemura T, Ota M, Katsuyama Y, Wada S, Mori H, Maruyama A, Shibata S, Nozawa Y, Kimura T, Morita S, Joshita S, Komatsu M, Matsumoto A, Kamijo A, Kobayashi M, Takamatsu M, Yoshizawa K, Kiyosawa K, Tanaka E.
- Journal Title
  
  Hum Immunol.
  
  Volume: 75 Issue: 8 Pages: 822-826
- DOI
  10.1016/j.humimm.2014.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22133002
[Journal Article] Qualitative measurement of pain by analyzing the salivary alpha amylase.2014
- Author(s)
  Tsuchiya, K., Saidin, MYB., Inoue, T., Kajiwara, K and Kimura, M.
- Journal Title
  
  Precision Engineering
  
  Volume: 38 Pages: 257-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] Human leukocyte antigen class II haplotypes affect clinical characteristics and progression of type 1 autoimmune hepatitis in Japan.2014
- Author(s)
  Umemura T, Katsuyama Y, Yoshizawa K, Kimura T, Joshita S, Komatsu M, Matsumoto A, Tanaka E, Ota M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 6 Pages: e100565-e100565
- DOI
  10.1371/journal.pone.0100565
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22133002, KAKENHI-PROJECT-26460996
[Journal Article] Neuropathy Target Esterase (神経障害標的エステラーゼ）遺伝子導入マウスの作製2014
- Author(s)
  加賀谷徹、割田貴之、三浦浩美、大塚正人、大久保朋一、坂部貢、木村穰
- Journal Title
  
  臨床環境医学
  
  Volume: 23(1)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma2014
- Author(s)
  Ken-ichi Aoyama, Yoshihide Ota, Kagemasa Kajiwara, Noriaki Hirayama, Minoru Kimura
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 452 Issue: 4 Pages: 980-985
- DOI
  10.1016/j.bbrc.2014.09.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462876
[Journal Article] Qualitative measurement of pain by analysing the salivary alpha amylase2013
- Author(s)
  Kazuyoshi Tsuchiya, Mohd Yusri Bin Saidin, Takehiko Inoue, Kagemasa Kajiwara, Minoru Kimura
- Journal Title
  
  Precision Engineering
  
  Volume: 38 Issue: 2 Pages: 257-260
- DOI
  10.1016/j.precisioneng.2013.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462876
[Journal Article] KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan.2013
- Author(s)
  Nozawa Y, Umemura T, Joshita S, Katsuyama Y, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Tanaka E, Ota M.
- Journal Title
  
  PLoS One
  
  Volume: 12;8(12) Issue: 12 Pages: e83381-e83381
- DOI
  10.1371/journal.pone.0083381
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22133002
[Journal Article] Improvement of pronuclear injection-based targeted transgenesis (PITT) by iCre mRNA-mediated site-specific recombination2013
- Author(s)
  Ohtsuka M, Miura H, Hayashi H, Nakaoka H, Kimura M, Sato M, Gurumurthy CB, Inoko H
- Journal Title
  
  Transgenic Research
  
  Volume: 22 Issue: 4 Pages: 873-875
- DOI
  10.1007/s11248-013-9703-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700514, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24700435, KAKENHI-PROJECT-25290035, KAKENHI-PROJECT-24651064
[Journal Article] X-ray microtomographic visualization of Escherichia coli by metalloprotein overexpression2013
- Author(s)
  Mizutani, R., Taguchi, K., Ohtsuka, M., Kimura, M., Takeuchi, A., Uesugi, K. and Suzuki, Y
- Journal Title
  
  Journal of Synchrotron Radiation
  
  Volume: 20 Pages: 581-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] Improved loop-mediated isothermal amplification for HLA-DRB1 genotyping using RecA and a restriction enzyme for enhanced amplification specificity2013
- Author(s)
  Mitsunaga S, Shimizu S, Okudaira Y, Oka A, Tanaka M, Kimura M, Kulski JK, Inoue I, Inoko H
- Journal Title
  
  Immunogenet
  
  Volume: 65(6) Issue: 6 Pages: 405-415
- DOI
  10.1007/s00251-013-0690-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241049, KAKENHI-PROJECT-22510213, KAKENHI-PROJECT-23390191, KAKENHI-PROJECT-24651064
[Journal Article] Improvement of pronuclear injection-based targeted transgenesis (PITT) by iCre mRNA-mediated site-specific recombination2013
- Author(s)
  Ohtsuka, M., Miura, H., Hayashi, H., Nakaoka, H., Kimura, M.., Sato, M. and Gurumurthy , CB
- Journal Title
  
  Transgenic Research
  
  Volume: 111 Pages: 111-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] シックハウス症候群スクリーニングを視野に入れたマウス・ラット眼球運動研究の応用2012
- Author(s)
  木村穣(5/5)
- Journal Title
  
  臨床環境医学
  
  Volume: 21 Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590666
[Journal Article] Association of sick building syndrome with neuropathy target esterase (NTE) activity in Japanese.2012
- Author(s)
  Matsuzaka Y
- Journal Title
  
  Environmental Toxicology
  
  Volume: 18 Issue: 10 Pages: 111-222
- DOI
  10.1002/tox.21839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590304, KAKENHI-PROJECT-23390191, KAKENHI-PROJECT-24651064
[Journal Article] PITT: Pronuclear Injection-Based Targeted Transgenesis, a Reliable Transgene Expression Method in Mice2012
- Author(s)
  Ohtsuka, M., Miura, H., Sato, M., Kimura, M., Inoko H., Gurumurthy, CB.
- Journal Title
  
  Exp Anim.
  
  Volume: 61 Pages: 489-502
- NAID
  10031121853
- Data Source
  KAKENHI-PROJECT-24651064
[Journal Article] シックハウス症候群スクリーニングを視野に入れたマウス・ラット眼球運動研究の応用2012
- Author(s)
  木村穣(他5名)
- Journal Title
  
  臨床環境医学
  
  Volume: 21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Fluorescent transgenic mice suitable for multi-color aggregation chimera studies2012
- Author(s)
  Kimura M.(他6名)
- Journal Title
  
  Cell Tissue Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Fluorescent transgenic mice suitable for multi-color aggregation chimera studies2012
- Author(s)
  Ohtsuka M, Miura H, Gurumurthy CB, Kimura M, Inoko H, Yoshimura S, Sato M
- Journal Title
  
  Cell and Tissue Research
  
  Volume: 350 Issue: 2 Pages: 251-260
- DOI
  10.1007/s00441-012-1470-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700514, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-24700435, KAKENHI-PROJECT-24651064, KAKENHI-PLANNED-22133002
[Journal Article] Craniofacial analysis of mice deficient in Sez12, the murine homolog of the DGCR2 gene on chromosome 22q11.22011
- Author(s)
  Kajiwara, K., Kimura, M.
- Journal Title
  
  J.Physiol.Sci.
  
  Volume: 60, Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Production Technique and Design for Painless Injection Needle2011
- Author(s)
  Kimura M (1/4), Kajiwara K (4/4)
- Journal Title
  
  International Conference on Micro–Manufacturing
  
  Volume: (ICOMM) Pages: 469-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590666
[Journal Article] Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube2011
- Author(s)
  Kimura M. (他7名)
- Journal Title
  
  J Anat.
  
  Volume: 219 (5) Pages: 589-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Craniofacial analysis of mice deficient in Sez12, the murine homolog of the DGCR2 gene on chromosome 22q11.22011
- Author(s)
  Kajiwara, K., Kimura, M.
- Journal Title
  
  Journal of Physiological Sciences
  
  Volume: 61(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] IκBL, a novel member of the nuclear IκB family, inhibits inflammatory cytokine expression2011
- Author(s)
  Kimura M.(他6名)
- Journal Title
  
  FEBS Lett
  
  Volume: 585 (22) Pages: 3577-3581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Production Technique and Design for Painless Injection Needle2011
- Author(s)
  Kimura, M., Kajiwara, K.(他2名)
- Journal Title
  
  International Conference on Micro -Manufacturing,ICOMM 2011
  
  Pages: 469-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Craniofacial analysis of mice deficient in Sez12, the murine homolog of the DGCR2 gene on chromosome 22q11.22011
- Author(s)
  Kajiwara K., Kimura M.
- Journal Title
  
  Journal of Physiological Sciences
  
  Volume: 61(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590666
[Journal Article] Mapping of susceptibility locus for endometriosis within the HLA region using microsatellite markers in Japanese women2010
- Author(s)
  Kimura M.(他9名)
- Journal Title
  
  Tissue Antigens
  
  Volume: 75 (1) Pages: 65-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression2010
- Author(s)
  Kimura M. (他11名)
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38(22)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] A Novel method for constructing murine cDNA library enriched with maternal mRNAs exhibiting de novo independent post-fertilization polyadenylation2005
- Author(s)
  Sakurai T, Sato M, Kimura M
- Journal Title
  
  Biochem Biophys Res Commun 327
  
  Pages: 688-699
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] Temporary developmental arrest after storage of fertilized eggs at 4℃ : Effects on embryonic development, maternal mRNA processing and cell cycle2005
- Author(s)
  Sakurai, T., Kimura M, Sato, M.
- Journal Title
  
  Molecular Human Reproduction 11(5)
  
  Pages: 325-333
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370005
[Journal Article] Divers patterns of poiy(A) tail elongation and shortning of murine maternal mRNAs from fully-grown oocyte to 2-cell embryo stages2005
- Author(s)
  Sakurai T, Sato M, Kimura M
- Journal Title
  
  Biochem Biophys Res Commun 336
  
  Pages: 1181-1189
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] Divers patterns of poiy(A) tail elongation and shortning of murine maternal mRNAs from fully-grown oocyte to 2-cell embryo stages2005
- Author(s)
  Sakurai T, Sato M, Kimura M
- Journal Title
  
  Biochem Biophys Res Commun. 336
  
  Pages: 1181-1190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] Temporal developmental arrest after storage of fertilized mouse eggs at 4oC : Effects on embryonic development, maternal mRNA processing and cell cycle2005
- Author(s)
  Sakurai T, Kimura M, Sato M
- Journal Title
  
  Mol.Human Reprod 11
  
  Pages: 325-333
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] A novel method for constructing cDNA library Enriched with maternal mRNAs exhibiting de novo independent post-fertilization polyadenylation.2005
- Author(s)
  Sakurai T, Sato M, Kimura M
- Journal Title
  
  Biochem Biophys Res Commun. 327
  
  Pages: 688-699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] A novel method for constructing murine cDNA library enriched with maternal mRNAs exhibiting de novo independent post-fertilization polyadenylation.2005
- Author(s)
  T.Sakurai, M.Sato, M.Kimura
- Journal Title
  
  Biochem.Biophys.Res.Commun. 327(3)
  
  Pages: 688-699
- Data Source
  KAKENHI-PROJECT-16570181
[Journal Article] Diverse patterns of poly(A) tail elongation and shortning of murine maternal mRNAs from fully grown oocyte to 2-cell embryo stages.2005
- Author(s)
  Sakurai, T., Sato, M., Kimura M.
- Journal Title
  
  Biochem.Biophys.Res.Comm. 336
  
  Pages: 1181-1189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370005
[Journal Article] A Novel Method for Constructing Murine cDNA Library Enriched with Maternal mRNAs Exhibiting De Novo Independent Post-Fertilization Polyadenylation2005
- Author(s)
  Sakurai, T., Sato, M., Kimura M.
- Journal Title
  
  Biochem.Biophys.Res.Comm. 327
  
  Pages: 688-699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370005
[Journal Article] Comparative analysis of a 229 kb medaka genomic region, containing that zic1 and zic4 genes, with Fugu, and mouse.2004
- Author(s)
  Ohtsuka M, Kikuchi N, Ozato K, Inoko H, Kimura M
- Journal Title
  
  Genomics 83
  
  Pages: 1063-1071
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14209015
[Journal Article] A new mouse model for renal lesions produced by intravenous injection of diphtheria toxin A-chain expression plasmid.2004
- Author(s)
  Nakamura S, Terashima M, Kikuchi, N Kimura M, Maehara T, Saito A, Sato
- Journal Title
  
  BMC Nephrology 5
  
  Pages: 4-4
- Data Source
  KAKENHI-PROJECT-15658084
[Journal Article] Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence.2003
- Author(s)
  Anzai A, Shiina T, Kimura N, YanagiyaK, Kohara S, Shigenari A, Yamagata T, Kulski JK, NaruseTK, Fujimori Y, Fukuzumi Y,. Yamazaki M, Tashiro H, Iwamoto C, Umehara Y, Tmanishi T, Meyer A, Ikeo K, GojoboriT, BahramS, Inoko H
- Journal Title
  
  Proc Nat Acad Sci USA 100
  
  Pages: 7708-7713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14209015
[Journal Article] Identification of IkBL as the second Major Histocompatibility Complex-linked susceptibility locus for rheumatoid arthritis.2003
- Author(s)
  Okamoto K, Makino S, Yoshikawa Y, Takaki A, Nagatsuka Y, Ota M, Tamiya G, Kimura A, Bahrain S, Inoko H
- Journal Title
  
  Am J Hum Genet 72
  
  Pages: 303-312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14209015
[Journal Article] A basolateral sorting motif in the MICA cytoplasmic tail.2002
- Author(s)
  Suemizi H, Radosavljevic M, Kimura M, Sadahiro S, Yoshimura S Bahrain S, Inoko H
- Journal Title
  
  Proc Natl Acad Sci USA 99
  
  Pages: 2971-2976
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14209015
[Patent] 穿刺針、微量体液採取用冶具および微量薬液投与用冶具2012
- Inventor(s)
  槌谷和義、木村穣、梶原景正、坂元公則
- Industrial Property Rights Holder
  高電工業株式会社、学校法人東海大学
- Industrial Property Number
  2012-106453
- Filing Date
  2012-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Simple and Effective Gamma-Ray Exposure System for Low-Dose-Rate Long Exposure to Mice.2024
- Author(s)
  Gondo, Y and Kimura, M.
- Organizer
  Biological Effects and Application of Radiation
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] Toward a New Risk Assessment System for Low-Dose/Low Dose/Rate Long Exposure to Radiation.2024
- Author(s)
  Gondo, Y. Uchiyama, A., Yoneya, M., Tanaka, S., Komura, J.,Kimura, M., Ohno, M., Toki, H., Bando, M., Tsunoyama, Y., Matsumoto, Y., Maki, H and Shimada, Y
- Organizer
  Biological Effects and Application of Radiation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 前庭―視覚組み合わせ刺激がマウスに食欲不振を引き起こす2023
- Author(s)
  加藤明、木村穣
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 前庭―視覚組み合わせ刺激が引き起こす動揺病症状と先行刺激による動揺病抑制2023
- Author(s)
  Katoh, A., Nakaya, N., Shimura, F and Kimura, M
- Organizer
  日本生理学会第100回記念大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 動揺病を引き起こす前庭―視覚環境変化とその予防へのアプローチ2023
- Author(s)
  加藤明、木村穰
- Organizer
  第31回日本臨床環境医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 神経障害エステラーゼ遺伝子操作マウスの解析2023
- Author(s)
  木村穰, 赤塚尚子, 水谷晃子, 畑中朋美, 伊藤誠敏, 坂部貢, 加藤明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 神経障害エステラーゼ遺伝子変異マウスの解析2022
- Author(s)
  木村穣、赤塚尚子、伊藤誠敏、坂部貢、畑中朋美、加藤明
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 遺伝子操作マウスを用いた神経障害エステラーゼの遺伝子の機能解析2022
- Author(s)
  木村穣、赤塚尚子、坂部貢、畑中朋美、加藤明
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] フタル酸エステルの経費吸収におけるエステラーゼの機能解析2021
- Author(s)
  畑中朋美、大山翠、武内智春、馬淵智生、木村穰
- Organizer
  第29回日本臨床環境医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 神経障害エステラーゼのマウス脳における昨日2021
- Author(s)
  木村穣、加藤明、赤塚尚子、伊藤正敏、坂部貢
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] 神経障害エステラーゼ活性および細胞増殖に対する有機リンの影響について2021
- Author(s)
  加賀谷徹、本杉奈美、坂部貢、木村穣
- Organizer
  第29回日本臨床環境医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06847
[Presentation] エステル化合物の代謝に寄与する加水分解酵素の皮膚中濃度2019
- Author(s)
  小林鈴、鹿倉愛里彩、田村真由美、武内智春、井上貴暁、藤堂浩明、杉林堅次、青山謙一、太田嘉英、今川孝太郎、赤松正、木村穣、畑中朋美
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] ほ乳類など産仔数の少ない生物種における遺伝的多様性産出と適応放散戦略の検証2018
- Author(s)
  権藤洋一、福村龍太郎、小瀧逸人、石塚祐一、中井祐治、牧野茂、本杉奈美、木村穣、森一樹、久原哲、豊田敦、藤山秋佐夫
- Organizer
  先進ゲノム支援合同班会議
- Data Source
  KAKENHI-PROJECT-17H00789
[Presentation] The Mouse Homolog of DGCR2 Gene Encoding within 22q11.2 Contributes to Enchondral Ossification in Skull Base and Its Defect Causes the Severity in 22q11.2 Deletion Syndrome2018
- Author(s)
  Kagemasa Kajiwara, Kenichi Aoyama, Masahiro Uchibori, Yoshihide Ota, Minoru Kimura, Kenji Tanigaki and Elisabeth Anne Illingworth
- Organizer
  100th AAOMS Annual Meeting. Scientific Sessions and Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11460
[Presentation] ヒトNeuropathy Target Esterase高発現マウスとマウスホモログ遺伝子変異マウスの行動解析2018
- Author(s)
  木村穣、加藤明、阿部如子、本杉奈美、坂部貢
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] Influence of formaldehyde gas exposure to reflexive eye movements in mice Mechanisms for stimulus generalization of learned changes in the vestibulo-ocular reflex.2018
- Author(s)
  加藤明、酒井駿一、遊部雅生、立崎武弘、坂部貢、木村穣
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] Dgcr2は軟骨内骨化過程における肥大軟骨細胞への分化過程でTGF-betaシグナルを抑制性に制御する2018
- Author(s)
  梶原景正, 渡部聡, 青山謙一, 内堀雅博, 大澤侑子, 太田嘉英, 木村穣
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K11460
[Presentation] 自然発生生殖細胞系列突然変異のほ乳類の発生段階における起源2018
- Author(s)
  権藤洋一、福村龍太郎、小瀧逸人、石塚祐一、中井祐治、牧野茂、森一樹、久原哲、豊田敦、藤山秋佐夫、木村穣
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-17H00789
[Presentation] マウスモデルに基づく胚発生の極初期に個体発がんドライバー変異が生じる可能性の示唆2018
- Author(s)
  権藤洋一、木村穣
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H00789
[Presentation] 有機リンによるNTE(Neuropathy Target Esterase)の活性阻害について2017
- Author(s)
  阿部如子、田中正史、本杉奈美、伊藤誠敏、大久保朋一、木村穣
- Organizer
  生命科学系合同年次大会（第40回日本分子生物学会年会、第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] Mutational landscape of Japanese oral squamous cell carcinoma2017
- Author(s)
  青山謙一、太田嘉英、内堀雅博、梶原景正、木村穣
- Organizer
  日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-15K11302
[Presentation] エステル化合物の経皮吸収におけるcarboxylesteraseの役割―シックハウス症候群との関連性―2017
- Author(s)
  畑中朋美、井上貴暁、田中　享、藤堂浩明、杉林堅次、内堀雅博、青山謙一、太田嘉英、今川孝太郎、赤松正、宮坂宗男、坂部貢、木村穣
- Organizer
  第26回日本臨床環境医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] エステル化合物の経皮吸収に寄与する加水分解酵素の組織学的解析2017
- Author(s)
  井上貴暁、中里優花、太田嘉英、赤松　正, 宮坂宗男、木村　穣、Wesam R. Kadhum、田中　享、藤堂浩明、杉林堅次、畑中朋美
- Organizer
  日本薬剤学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] エステル化合物の経皮吸収におけるcarboxyesteraseの役割―シックハウス症候群との関連性―2017
- Author(s)
  畑中朋美、井上貴暁、田中亨、藤堂浩明、杉林堅次、内堀雅博、青山謙一、太田嘉英、今川孝太郎、赤松正、宮坂宗男、坂部貢、木村穣
- Organizer
  第２６回日本臨床環境医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] 22q11.2欠失症候群の骨格異常に関するDGCR2のTGF-betaシグナル制御メカニズム2017
- Author(s)
  梶原景正, 青山謙一, 内堀雅博, 斎藤雅幸, 弥栄聡介, 太田嘉英, 木村穣
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K11460
[Presentation] 日本人口腔扁平上皮癌に見いだされた変異型NOTCH1分子の発現解析2016
- Author(s)
  内堀雅博, 太田嘉英, 青山謙一, 梶原景正, 木村穣
- Organizer
  日本生化学会大会・日本分子生物学会年会合同大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K11302
[Presentation] シアル酸修飾制御はリソソーム内分解のほかオートファジー開始にも重要である2016
- Author(s)
  赤塚尚子、Odontuya Davaadorj、木村穣、鈴木崇弘、関島良樹、大野田秀樹、佐藤健人
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290066
[Presentation] ヒトNeuropathy Target Esterase遺伝子導入マウスを用いたシックハウス症候群関連物質の生体影響の解析2016
- Author(s)
  木村　穣、加藤　明、本杉奈美、大久保朋一、畑中朋美、坂部貢、田中正史
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] ヒト皮膚におけるエステル化合物の経皮吸収挙動－carboxylesterase皮膚内代謝の影響2016
- Author(s)
  畑中朋美、中里優花、井上貴暁、田中　享、藤堂浩明、杉林堅次、内堀雅博、太田嘉英、今川孝太郎、赤松正、宮坂宗男、坂部貢、木村　穣
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] 口腔扁平上皮癌由来の変異NOTCH1を導入したHEK293はNICDの発現と細胞増殖が低下する2016
- Author(s)
  内堀雅博, 青山謙一, 太田嘉英, 梶原景正, 田中正史, 木村穣
- Organizer
  日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K11302
[Presentation] The role of corticotropin releasing factor on motor learning.2016
- Author(s)
  Takeuchi E, Hatanaka T, Katoh A and Kimura M.
- Organizer
  10th FENS Forum 2016
- Place of Presentation
  Bella Center (Denmark, Copenhagen)
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] ヒトNeuropathy Target Esterase遺伝子導入マウスを用いたシックハウス症候群関連化学物質の生体影響の解析2016
- Author(s)
  木村穣、加藤明、本杉奈美、大久保朋一、畑中朋美、坂部貢、田中正史
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] ヒト皮膚におけるエステル化合物の経皮吸収挙動2016
- Author(s)
  畑中朋美、中村優花、井上貴暁、田中亨、藤堂浩明、杉林堅次、内堀雅博、太田嘉英、今川孝太郎、赤松正、宮坂宗男、坂部貢、木村穣
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] 22q11.2欠失症候群の骨格異常に関するDGCR2遺伝子のノックアウトマウスを用いた病因解析2016
- Author(s)
  梶原　景正, 青山　謙一, 内堀　雅博, 渡部聡, 金澤花帆, 太田　嘉英, 木村　穣
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県　パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K11460
[Presentation] ヒトにおけるフタル酸エステルの経皮吸収から見たシックハウス症候群について2016
- Author(s)
  畑中朋美、杉野雅浩、從二和彦、内堀雅博、太田嘉英、今川孝太郎、赤松正、宮坂宗男、坂部貢、木村穣
- Organizer
  第25回日本臨床環境医学会学術集会
- Place of Presentation
  郡山商工会議所（郡山）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K00625
[Presentation] ヒトにおけるフタル酸エステルの経皮吸収から見たシックハウス症候群について2016
- Author(s)
  畑中朋美、杉野雅浩，從二和彦，内堀雅博，太田嘉英，今川孝太郎，赤松正，宮坂宗男，坂部貢，木村穣
- Organizer
  第25回日本臨床環境医学会学術集会
- Place of Presentation
  郡山商工会議所（福島県郡山市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] Positive contribution of corticotropin releasing factor on motor learning.2016
- Author(s)
  Katoh A, Hatanaka T, Kimura M, Takeuchi E.
- Organizer
  15th MOLECULAR and CELLULAR COGNITION SOCIETY MEETING
- Place of Presentation
  Westin Gaslamp Quarter&Convention Center (USA, San Diego)
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] ホルムアルデヒドガス曝露による反射性眼球運動への影響2016
- Author(s)
  加藤明，三島亜希子，麥倉信一郎，立崎武弘，遊部雅生，坂部貢，木村穣
- Organizer
  第25回日本臨床環境医学会学術集会
- Place of Presentation
  郡山商工会議所会館（福島県郡山市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] Ambra1はT細胞レセプターに下流で制御されるミトコンドリアの生合成と品質管理に重要である2016
- Author(s)
  久我周平、赤塚尚子、大塚正人、木村穣、井ノ上逸朗、佐藤健人
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290066
[Presentation] ヒトNeuropathy Target Esteras遺伝子導入マウスを用いたシックハウス症候群関連化学物質の生体影響の解析2016
- Author(s)
  木村穣, 加藤明, 本杉奈美, 大久保朋一, 畑中朋美, 坂部貢, 田中正史
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K01603
[Presentation] The functional analysis of NOTCH1 mutations found in Japanese oral carcinom2015
- Author(s)
  KI Aoyama, Y Ota, M Uchibori, K Kajiwara, M kimura
- Organizer
  日本癌学会学術大会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K11302
[Presentation] シックハウス症候群におけるNTE活性の役割に関する研究ーフタル酸エステルの経皮吸収に及ぼす影響II2015
- Author(s)
  杉野雅浩、畑中朋美、荻野瑛里奈、従二和彦、青山謙一、内堀雅博、太田嘉英、今川孝太郎、宮坂宗男、竹内絵理、坂部貢、従二和彦、木村穣
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会合同大会
- Place of Presentation
  兵庫県神戸市、神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] シックハウス症候群原因物質の経皮吸収に及ぼすNTE活性の影響2015
- Author(s)
  畑中朋美、荻野瑛里奈、山村勇貴、本杉奈美、竹内絵理、坂部貢、杉野雅浩、従二和彦、木村穣
- Organizer
  第２４回日本臨床環境医学会学術集会
- Place of Presentation
  兵庫県神戸市、神戸ポートアイランド
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] マウスDgcr2遺伝子はTGF-βシグナルを介して分化軟骨細胞の増殖を制御する2015
- Author(s)
  梶原景正, 青山謙一, 内堀雅博, 清陸王, 渡部聡, 木村穣
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] 日本人口腔字扁平上皮癌に見いだされた変異型NOTCH1分子の発現解析2015
- Author(s)
  内堀雅博, 太田嘉英, 青山謙一, 梶原景正, 木村穣
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] NOTCH1 mutation found in Japanese oral carcinoma2015
- Author(s)
  KI Aoyama, Y Ota, M Uchibori, K Kajiwara, M kimura
- Organizer
  European Cancer Congress 2015
- Place of Presentation
  Wien Exhibition and Congress Center （オーストリア・ウィーン）
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11302
[Presentation] コーデン症候群患者由来iPS細胞の樹立と解析2015
- Author(s)
  赤塚尚子、大塚正人、木村穣、井ノ上逸朗、佐藤健人
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸市、神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290066
[Presentation] シックハウス症候群におけるNTE活性の役割に関する研究ーフタル酸エステルの経皮吸収に及ぼす影響I2015
- Author(s)
  畑中朋美、荻野瑛里奈、本杉奈美、竹内絵理、坂部貢、杉野雅浩、従二和彦、木村穣
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会合同大会
- Place of Presentation
  東京都港区、北里大学薬学部
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K12215
[Presentation] 線虫寿命モデルの網羅的解析を用いたダイオウ薬効に関わるヒト分子メカニズムの解明2013
- Author(s)
  梶原景正(1/6)、石井直明(4/6)、木村穣(5/6)、新井信(6/6)
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Year and Date
  2013-08-31
- Data Source
  KAKENHI-PROJECT-22590666
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のマウスホモログDgcr2のTGF-βシグナルへの影響2013
- Author(s)
  梶原景正、麥倉信一郎、渡部聡、木村穣
- Organizer
  日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] マウス繊維芽細胞においてSez12はTGF-ß シグナルに関与している2013
- Author(s)
  麥倉信一郎、渡邊聡、梶原景正、木村穣
- Organizer
  第36 回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] 有機リンの培養細胞に及ぼす効果について(1)2013
- Author(s)
  割田貴之、本杉奈美、田中正史、大久保朋一、坂部貢、木村穣
- Organizer
  第22回日本臨床環境医学会学術集会
- Place of Presentation
  東京（日本歯科大学東京短期大学）
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] Neuropathy target esterase(神経障害標的エステラーゼ)遺伝子導入マウスの作成2013
- Author(s)
  加賀谷徹、割田貴之、三浦浩美、大塚正人、大久保朋一、坂部貢、木村穣
- Organizer
  第22回日本臨床環境医学会学術集会
- Place of Presentation
  東京（日本歯科大学東京短期大学）
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のTGF-β/BMP シグナルとの相互作用2013
- Author(s)
  梶原景正、渡邊聡、麥倉信一郎、木村穣
- Organizer
  第36 回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のTGF-β/BMPシグナルとの相互作用2013
- Author(s)
  梶原景正、麥倉信一郎、渡部聡、木村穣
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] 雄性不妊を呈するヒト疾患モデルマウスでの造精機能回復の試み2013
- Author(s)
  本杉奈美,亀山洋子,木村穣
- Organizer
  第36 回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] pnpla6遺伝子と有機リン感受性ートランスジェニックマウス作製と遺伝子導入細胞の性質ー2013
- Author(s)
  加賀谷徹,大塚正人,三浦浩美,大久保朋一,田中正史,割田貴之,本杉奈美,坂部貢,梶原景正,加藤明, 吉川枝里,木村穣
- Organizer
  第36 回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] 線虫を用いたダイオウ薬効に関わるヒト分子メカニズムの網羅的解析2012
- Author(s)
  梶原景正(1/7)、木村穣(5/7)、石井直明(6/7)、新井信(7/7)
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-09-02
- Data Source
  KAKENHI-PROJECT-22590666
[Presentation] 線虫を用いたダイオウ薬効に関わるヒト分子メカニズムの網羅的解析2012
- Author(s)
  梶原景正、安田佳代、田中政之、林秀樹、木村穣、石井直明、新井信
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12, the Murine Homolog of DGCR2 Gene Laid within the Microdeletion of 22q11.2 Deletion Syndrome, Functions in the Endochondral Ossification2012
- Author(s)
  K.Kajiwara, S. Mugikura, S. Watanabe, M.Kimura
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] 穿刺時間に対する唾液中αアミラーゼ量変動2012
- Author(s)
  Yusri Mohd、槌谷和義、梶原景正、木村穣
- Organizer
  精密工学会大会学術講演会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] 新規レクチンをコードするSez12はT細胞増殖シグナルを調節する2012
- Author(s)
  麥倉信一郎、渡部聡、梶原景正、木村穣
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] The Sez12, Coding the C-type Lectin-like Domain-containing Membrane Protein, Plays a Regulatory Role in T Cell Growth2012
- Author(s)
  S. Mugikura, S. Watanabe, K.Kajiwara, M.Kimura
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のマウスホモログSez12遺伝子の軟骨細胞分化への影響2012
- Author(s)
  梶原景正、麥倉信一郎、渡部聡、木村穣
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] サブスタンスPによる注射針穿刺時の痛みの客観的評価手法の確立2012
- Author(s)
  モハマド・ユスリ、梶原景正、木村穣
- Organizer
  精密工学会大会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12, the Murine Homolog of DGCR2 Gene Laid within the Microdeletion of 22q11.2 Deletion Syndrome, Functions in the Endochondral Ossification2012
- Author(s)
  Kajiwara K (1/4), Kimura M (4/4)
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22590666
[Presentation] Targeted disruption of the mouse homolog of the DGCR2 gene, Sez12, causes a nasal septum abnormality and some dental problems in mice2011
- Author(s)
  梶原景正、木村穣
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] 顎顔面領域の形態形成に関わるDgcr2ホモログSez12とTbx1との比較解析2011
- Author(s)
  梶原景正、木村穣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] 顎顔面領域の形態形成に関わるDgcr2ホモログSez12とTbx1との比較解析2011
- Author(s)
  梶原景正(1/3)、木村穣(3/3)
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22590666
[Presentation] 顎顔面領域の形態形成に関わるDgcr2ホモログSez12とTbx1との比較解析2011
- Author(s)
  梶原景正、麥倉信一郎、木村穣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12遺伝子欠失マウスの免疫系細胞における細胞増殖能の検討2011
- Author(s)
  梶原景正、木村穣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12遺伝子欠失マウスの免疫系細胞における細胞増殖能の検討2011
- Author(s)
  麥倉信一郎、千葉朋希、渡部聡、梶原景正、木村穣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Ali14変異マウスを用いた受精におけるホスホリパーゼCγ2の機能解析2011
- Author(s)
  荻原早苗、Auke Boersma, 本杉奈美、中村健司、Susan Marschall, Martin Hrabe de Angelis, 木村穣、阿部幸一郎
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-22500392
[Presentation] Targeted disruption of the mouse homolog of the DGCR2 gene, Sez12, causes a nasal septum abnormality and some dental problems in mice2010
- Author(s)
  梶原景正、麥倉信一郎、木村穣
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] DGCR2遺伝子のマウスホモログSez12遺伝子ノックアウトマウスの胸腺細胞分化の解析2010
- Author(s)
  麥倉信一郎、梶原景正、木村穣
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] EndoGalCとtargeted toxin法の組み合わせを用いたCRISPR系でノックアウトされた遺伝子改変細胞濃縮法の開発
- Author(s)
  渡部聡、桜井敬之、中村伸吾、梶原景正、木村穣、佐藤正宏
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] 口腔扁平上皮癌にみられた変異型NOTCH1の性質は、機能変化を生じている可能性がある
- Author(s)
  青山謙一、太田嘉英、内堀雅博、金子明寛、梶原景正、木村穣
- Organizer
  第33回日本口腔腫瘍学会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] マウスDgcr２遺伝子は軟骨細胞の増殖分化制御により骨格形成に影響を与える
- Author(s)
  梶原景正、渡部聡、木村穰
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] NOTCH1 遺伝子変異による口腔扁平上皮癌の予後の検討
- Author(s)
  内堀雅博、青山謙一、太田嘉英、金子明寛、梶原景正、木村穣
- Organizer
  第33回日本口腔腫瘍学会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] NTE(神経障害標的エステラーゼ)遺伝子発現マウスと有機リン代謝
- Author(s)
  山村勇貴、本杉奈美、三浦浩美、大塚正人、大久保朋一、吉野美千代、笹川昇、坂部貢、木村穰
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] EndoGalCとtargeted toxinの組み合わせを用いたCRISPR系でノックアウトされた遺伝子改変細胞濃縮法の開発
- Author(s)
  渡部聡、桜井敬之、中村伸吾、梶原景正、木村穰、佐藤正宏
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24651064
[Presentation] iPS細胞樹立前後の同一性確認のためのNGSを用いた第4区域までのHLAタイピング
- Author(s)
  末上　伸二、小島　裕人、鈴木　進悟、尾崎　有紀、椎名　隆(ＣＡ)、光永　滋樹、猪子　英俊、佐治　博夫、木村　貴文
- Organizer
  第21回日本組織適合性学会近畿地方会
- Place of Presentation
  京都大学（京都）
- Data Source
  KAKENHI-PLANNED-22133002

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KIMURA Minoru 木村 穣

木村 穰 キムラ ミノル

木村 穣 キムラ ミノル

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Analyses for the new function of the neuropathy target esterase using genetically engineered mice.Principal Investigator

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Towards the diagnosis method for the toxicity of organophosphorusPrincipal Investigator

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Developing the Universal iPS cell lines using genetic engineering systemPrincipal Investigator

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Analysis for the function of the candidate gene of Sick House Syndrome and development of disease model mousePrincipal Investigator

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KIMURA Minoru 木村穣

木村穰キムラミノル

木村穣キムラミノル